The invention relates to a rhesus monkey erythrocyte adsorber, belonging to the field of medicine science. According to the rhesus monkey erythrocyte adsorber, rhesus monkey erythrocytes replace human Rh positive O erythrocytes, the rhesus monkey erythrocytes are washed by 4 DEG C normal saline and 37 DEG C normal saline, so that immune antibodies or natural antibody attaching to the surfaces of the erythrocytes can be removed, after antigenicity detection, cell sediment is added into a cylindrical adsorber made of a material with high biocompatibility till 4/5 of the volume is occupied, then 3.5% of mannitol erythrocyte preserving fluid is added, so that the concentration of the erythrocyte achieves 80%, shaking is carried out gently for uniform mixing, the opening is sealed, and the product is stored at 4 DEG C for regular use, wherein a screen is arranged at the opening of a purifier, so that a line of defense for preventing cell debris from being filtered out is formed, after the plasma is filtered, Rh antibodies are combined with Rh positive rhesus monkey erythrocytes to form a fixed compound, the broken erythrocyte debris and the macromolecular compound combined with the broken erythrocyte debris are blocked by the screen of the purifier, and the plasma with morbid substance removed is filtered by the purifier and then conveyed back, so that the purpose of treating blood-group-incompatible haemolytic diseases is achieved by eliminating Rh antibodies of the plasma.