The present invention provides methods for treating tumors in subjects by using a
recombinant interferon (rSIFN-co), and optionally, methods for treating
solid tumors, such as
lung cancer, among others, with or without prior
surgery, and as a first line or second line monotherapy or in combination with one or more other anti-tumor therapies. The present invention further provides non-
surgical methods for eliminating tumors or reducing tumor sizes in subjects, and / or preventing postoperative
tumor recurrence and / or metastases in subjects by using the
recombinant interferon (rSIFN-co) which comprises a unique
spatial configuration, alone or in conjunction with radiotherapy,
chemotherapy, and / or one or more anti-tumor drugs such as biological agents, targeted drugs, small molecules,
Traditional Chinese Medicine (TCM) and the like.