Oral liquid synergistic agent for livestock, poultry and aquatic product, and preparation method thereof

A technology for aquatic animals and oral liquids, applied in medical raw materials derived from reptiles, medical preparations containing active ingredients, liquid delivery, etc., can solve problems such as limited immune effect, inconvenient vaccination, and uncertainty in epidemic prevention

Inactive Publication Date: 2008-12-03
雷清莲
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are many types of vaccines for various animal epidemics on the market, basically there are two main types, namely inactivated vaccines and attenuated vaccines. The immune characteristics of the vaccines, the time to produce immunity, the length of the immunity period, Vaccines produced by different manufacturers are different, which brings great inconvenience to farms when vaccinating. At the same time, the immune effect is very limited and uncertain, which brings great uncertainty to the prevention of epidemics.

Method used

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  • Oral liquid synergistic agent for livestock, poultry and aquatic product, and preparation method thereof
  • Oral liquid synergistic agent for livestock, poultry and aquatic product, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Embodiment one: preparation of oral liquid 1 of medicine of the present invention

[0014] (1) Weigh 10 grams of ginkgo biloba leaves, 15 grams of honeysuckle, 5 grams of echinacea, 10 grams of coriander root, 8 grams of purslane, 10 grams of plantain, 15 grams of rehmannia, 2 grams of snake gall, 10 grams of ox gall, aloe 40 grams, 25 grams of rock sugar, 10 grams of recombinant interferon, and 5 grams of aminovitamin.

[0015] (2) Add water to decoct the raw materials except genetic recombinant interferon and aminovitamin twice, add 8 times the amount of water for the first time, decoct for 2 hours, add 6 times the amount of water for the second time, decoct for 1 hour, combine Two decoctions, filtered to obtain the filtrate, concentrated into an extract with a specific gravity of 1.35, adding 85-95% edible glacial acetic acid for extraction, recovering the glacial acetic acid and concentrating, drying at 45-50°C to obtain a dry extract 55.1 gram;

[0016] (3) Grind...

Embodiment 2

[0018] Embodiment two: the oral liquid 2 preparation of medicine of the present invention

[0019] (1) Weigh 25 grams of ginkgo biloba leaves, 25 grams of honeysuckle, 20 grams of echinacea, 20 grams of coriander root, 20 grams of purslane, 20 grams of plantain, 25 grams of rehmannia, 5 grams of snake gall, 20 grams of ox gall, aloe 60 grams, 40 grams of rock sugar, 20 grams of recombinant interferon, and 15 grams of aminovitamin.

[0020] (2) Add water to decoct the raw materials except genetic recombinant interferon and aminovitamin twice, add 8 times the amount of water for the first time, decoct for 2 hours, add 6 times the amount of water for the second time, decoct for 1 hour, combine Two decoctions, filtered to get the filtrate, concentrated into an extract with a specific gravity of 1.35, adding 85-95% edible glacial acetic acid for extraction, recovering the glacial acetic acid and concentrating, drying at 45-50°C to obtain a dry extract 105.4 gram;

[0021] (3) Gri...

Embodiment 3

[0023] Embodiment three: medicine of the present invention has preventive effect to the porcine blue-ear disease of young pig

[0024] Get 30 young pigs, inject the same porcine PRRS vaccine to every young pigs, be divided into three groups at random, every group of 10, 1 group is feeding normally every day, 2 groups add 0.5 liters of oral liquid of the present invention 1,3 Add 0.5 liter of oral solution 2 of the present invention to the group.

[0025] After feeding for 2 days, a pig suffering from PRRS was added to each of the four groups, and the growth of young pigs in each group was observed.

[0026] The results are shown in Table 1. The results show that the medicine of the invention has obvious preventive and therapeutic effects on the piglet blue-ear disease.

[0027] The prevention and treatment effect of medicine of the present invention to the porcine blue-ear disease of young pig of table 1

[0028]

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Abstract

The invention discloses an oral liquid synergistic agent for vaccines of livestock, poultry and aquatic animals and a preparation method thereof. The oral liquid synergistic agent for the vaccines is prepared from the following materials by weight portion: 10 to 25 portions of ginkgo leaves, 15 to 25 portions of Japanese honeysuckle stem, 5 to 20 portions of echinacea purpurea root, 10 to 20 portions of cogongrass rhizome, 8 to 20 portions of purslane, 10 to 20 portions of plantain, 15 to 25 portions of rehmanniae, 2 to 5 portions of snake gall, 10 to 20 portions of ox gall, 40 to 60 portions of aloe, 25 to 40 portions of rock candy, 10 to 20 portions of gene recombinant interferon and 5 to 15 portions of amino vitamin. The oral liquid synergistic agent for the vaccines disclosed by the invention can be directly mixed with normal feed of animals or directly mixed with water drunk by the animals, thereby effectively improving the immunity of an organism and disease resistant capability of the livestock, the poultry and the aquatic animals and eliminating the mutual interference among the vaccines, strengthening the immune effect of the combined vaccine, improving the immunity of the vaccines and making organisms of the animals have good immune effects for the vaccines.

Description

【Technical field】 [0001] The invention relates to a veterinary pharmaceutical composition and a preparation method thereof. 【Background technique】 [0002] The aquaculture industry is an advantageous industry in our country with broad prospects for development. In recent years, the income of the aquaculture industry has grown rapidly, but every time a major animal epidemic occurs, it will cause huge losses to the aquaculture industry. According to estimates, the direct loss caused by animal disease and death in my country is nearly 40 billion yuan each year, which is equivalent to about 60% of the increase in the total output value of the aquaculture industry. [0003] As a big breeding country in my country, zoonotic diseases occur from time to time. Long-standing animal anthrax, tuberculosis, brucellosis, salmonellosis, rabies, and Japanese encephalitis are directly or indirectly derived from animals. In 2005, the first case of human infection with avian influenza appear...

Claims

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Application Information

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IPC IPC(8): A61K38/21A61K9/10A61P31/12A61P31/04A61P37/04A61K35/58A61K35/413A61K36/899A61K35/583
Inventor 谢兴荣刘治西唐兆新郭世宁汪连涛王芝武帮勇吴国辉陈胜叶亚多潘永发林仕
Owner 雷清莲
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