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126results about How to "Stable production" patented technology

Adaptive AI fault diagnosis model fusing reinforcement learning and industrial equipment predictive maintenance system

The invention relates to the technical field of fault diagnosis models, and discloses an adaptive AI fault diagnosis model fusing reinforcement learning and an industrial equipment predictive maintenance system. Comprising an industrial equipment data acquisition and preprocessing module, a reinforcement learning-fused adaptive fault diagnosis model module, an equipment health degree evaluation and residual life prediction module, a predictive maintenance decision and execution module and a system management and integration module, and the output end of the industrial equipment data acquisition and preprocessing module is electrically connected with the input end of a self-adaptive fault diagnosis model module fusing reinforcement learning. According to the system, data during equipment operation are effectively collected, the equipment health degree evaluation module is matched to convert the feature deviation degree into 0-100 visual scores, the health trend visualization unit displays changes through a broken line diagram and a thermodynamic diagram, fault risk points are marked, historical backtracking and multi-equipment comparison are supported, non-professional personnel can also rapidly judge the equipment state, and the equipment health degree evaluation module is matched to convert the feature deviation degree into 0-100 visual scores. And the equipment management efficiency is improved by 30%.
Owner:HANGZHOU MENGJUE TECHNOLOGY CO LTD

Precision mold with inner side back-off core-pulling mechanism

A precision mold provided with an inner side back-off core-pulling mechanism belongs to the field of thermoplastic plastic forming molds, and realizes first separation of a fixed mold plate and a movable mold plate and later separation of the movable mold plate and a movable mold base plate by utilizing the matching effect of mold opening force and a damping pin, and drives a sliding connecting piece to move by utilizing the separation of the movable mold base plate so as to promote a sliding insert to return for core pulling. And the first core-pulling insert and the second core-pulling insert are separated from the inner side inverted buckle in a sliding manner, so that smooth demolding of the inner side inverted buckle of a product is realized, the mold space is saved, the mold cost is saved, the mold structure is simplified, the stability of the production process of a plastic product is ensured, the production efficiency is improved, and the reject ratio is reduced.
Owner:DALIAN LUANYI PRECISION ENG

Wine peach kernel decoction pieces and preparation method thereof

The invention discloses wine peach kernel decoction pieces and a preparation method thereof, and the method comprises the following steps: adding 10-20% by mass of yellow wine into peeled and cleaned peach kernels, uniformly stirring, and moistening at room temperature for 20-40 minutes to enable the yellow wine to be soaked and absorbed; and placing the moistened peach kernels in a drum-type herbal medicine roaster, frying at 100-140 DEG C for 10-20 minutes until the water content is 3-12%, and cooling to obtain the wine peach kernel decoction pieces with wine aroma. The wine peach kernel decoction pieces prepared by the method disclosed by the invention have the extract content of 21-31% and the amygdalin content of 2.4-3.6%, and are suitable for large-scale stable production.
Owner:SICHUAN VITA BIOTECHNOLOGY CO LTD

Final assembly equipment for spot welding and cutting automatic machine

ActiveCN224059177UFlexible adjustment of movement methodsPrecise motion control capabilitiesOther manufacturing equipments/toolsHydraulic cylinderMachine
The utility model relates to the technical field of spot welding and cutting, and discloses spot welding and cutting automatic machine general assembly equipment which comprises a first supporting plate, the upper surface of the first supporting plate is fixedly connected with a first hydraulic cylinder, the output end of the first hydraulic cylinder is fixedly connected with a first die, the interior of the first supporting plate is fixedly connected with a first connecting rod, and the first connecting rod is fixedly connected with a second die. And the outer wall of the first connecting rod is slidably connected to the interior of the first mold, a second supporting plate is fixedly connected to the lower surface of the first connecting rod, a sliding assembly is arranged on the lower surface of the second supporting plate, and the sliding assembly is used for driving materials to slide. According to the utility model, the electric push rod is started to drive the second mold to slide, so that the first sliding block slides along with the sliding of the second mold, finally, the purpose of sliding the second mold is realized, and when parts with different specifications and shapes are required to be combined by a general assembly, the pressing and sliding assembly can flexibly adjust the action mode according to the assembly process.
Owner:KUNSHAN YUDENGYI AUTOMATION CO LTD

Long-casting-time production method of food-grade tinplate

The invention belongs to the technical field of metallurgy, and particularly relates to a long-casting-time production method of food-grade tinplate. The tinplate comprises the following chemical components in percentage by mass: 0.040%-0.060% of C, less than or equal to 0.020% of Si, 0.20%-0.30% of Mn, less than or equal to 0.015% of P, less than or equal to 0.0080% of S, 0.025%-0.040% of Al, less than or equal to 0.060% of Cr, less than or equal to 0.060% of Cu, less than or equal to 0.060% of Ni, less than or equal to 0.010% of Nb, less than or equal to 0.010% of V, less than or equal to 0.010% of Ti, less than or equal to 0.0030% of B and the balance of iron and inevitable impurities. The production method comprises the steps of converter smelting, LF furnace refining, RH furnace net circulation and continuous casting protective pouring. On the basis of ensuring the cleanliness of the molten steel, the casting times are increased to more than 30, the production efficiency is high, and the product quality is good.
Owner:RIZHAO STEEL HLDG GROUP

A CNC machine tool tool wear monitoring method and system based on acoustic vibration sensing technology

The application discloses a kind of CNC machine tool tool wear monitoring method and system based on acoustic vibration sensing technology, which comprises: obtaining tool number, processing state from machine tool;Cutting vibration signals in the machining process of machine tool are collected by acoustic vibration sensor;The cutting vibration signals are preprocessed, time domain characteristic indexes and frequency domain characteristic indexes are extracted, and a comprehensive wear coefficient is calculated;According to the interval where the comprehensive wear coefficient is located, the state of the tool is judged;If the tool reaches the failure level, a prompt signal is sent out.The method is suitable for detecting common tool failure states and can be used in machine tools with different tool tooth numbers, different speeds and different machining processes.These indicators can be effectively used to evaluate tool wear in actual manufacturing processes, and play a crucial role in improving production capacity and promoting high-quality production.
Owner:YINGTAI LISHENG (SUZHOU) TECH CO LTD

Automatic dust cleaning structure of cement rotary kiln burner

The utility model relates to an automatic dust cleaning structure of cement rotary kiln burner, including cement rotary kiln burner structure, is provided with air cannon automatic dust cleaning pipe fitting structure at the top of cement rotary kiln burner structure, air cannon automatic dust cleaning pipe fitting structure includes the dust cleaning main pipe set between the cylinder structure and anchor fastener at the top of cement rotary kiln burner structure, the dust cleaning spray head body structure of uniform distribution setting on the dust cleaning main pipe upper portion and the air cannon gas transmission pipeline connected in the dust cleaning main pipe rear end and the air cannon gas transmission pipeline connection air cannon generating device. This structure can clean the top dust in time in operation, reduces the dust of burner center line subsidence under the adverse environment of burner, improves the clinker section burning quality and reduces the damage of burner protection layer caused by artificial cleaning, guarantees the normal operation of burner, ensures the stable production of kiln section burning system, improves the production economic benefits.
Owner:安徽芜湖海螺建筑安装工程有限责任公司

Application of PpWRKY53 transcription factor in improving heat resistance of Chinese pear fruits

The invention discloses an application of a PpWRKY53 transcription factor in improving heat resistance of Chinese pear fruits, the transcription factor is a positive regulatory factor of Chinese pears responding to high temperature stress, overexpression of the transcription factor PpWRKY53 gene in the Chinese pear fruits can significantly reduce hydrogen peroxide accumulation and membrane lipid peroxidation caused by high temperature, effectively alleviate water stain type browning symptoms of the fruits, and improve the heat resistance of the Chinese pears. The fruit hardness is improved. The invention provides a key gene resource for creating new germplasm of heat-resistant Chinese pears and breeding new varieties with high-temperature-resistant characteristics, and has important scientific and application values for ensuring stable production of summer Chinese pear industry and improving fruit quality and economic benefits.
Owner:YANGZHOU UNIV

A battery-powered door lock

This utility model discloses a battery-powered door lock, including a base, a circuit board, a power supply module, a conductive spring, and a power supply cover. The base has a power supply mounting hole and an electronic control mounting cavity; the circuit board is disposed in the electronic control mounting cavity; the power supply module is inserted into the power supply mounting hole along its depth direction, and a conductive part is disposed on the outer side of the power supply module; the conductive spring is disposed on the base and located at the bottom of the power supply mounting hole, one end of the conductive spring is connected to and conducts electricity with the circuit board, and the other end of the conductive spring abuts against the conductive part of the power supply module; the conductive spring can apply a force to disengage the power supply module from the power supply mounting hole; the power supply cover is detachably disposed on the base and can cover or open the opening of the power supply mounting hole.
Owner:ZHONGSHAN YANGGE LOCK CO LTD

Self-circulation water replenishing device for tailing overflow of magnetic separator

The utility model relates to the technical field of coal dressing, in particular to a magnetic separator tailing overflow self-circulation water replenishing device which comprises a magnetic separator, a feeding port of the magnetic separator is connected with a dilute medium barrel through a feeding pipe, a water pump is arranged on the feeding pipe, a water inlet of the dilute medium barrel is connected with a water replenishing pipeline, and an overflow pipe of the magnetic separator is located above an opening of the dilute medium barrel. An overflow pipe of the magnetic separator is connected with one end of a backflow pipeline, the other end of the backflow pipeline is located above the dilute medium barrel and close to an opening of the dilute medium barrel, and water overflowing from the overflow pipe of the magnetic separator flows into the dilute medium barrel through the backflow pipeline under the action of gravity. According to the utility model, water overflowing from the overflow pipeline of the magnetic separator can automatically flow to the dilute medium barrel to be used as replenished water, so that the circulation of water resources in the coal dressing system is realized, the use of external water is reduced, additional equipment is not needed, and unnecessary power consumption is effectively reduced, energy is saved and consumption is reduced while the production process is stabilized.
Owner:XINWEN MINING GROUP

Molding method of magnesium oxide-based carbon dioxide adsorbent suitable for large-scale preparation

The invention discloses a forming method of a magnesium oxide-based carbon dioxide adsorbent suitable for large-scale preparation. The forming method comprises the following steps: calcining a magnesium-containing precursor to prepare porous magnesium oxide raw powder; the preparation method comprises the following steps: carrying out impregnation modification on magnesium oxide raw powder and an alkali metal salt solution to obtain wet mixed thick slurry, drying the slurry, and carrying out secondary calcination to obtain modified adsorbent raw powder; and mixing the raw powder with deionized water, a forming aid and the like to prepare a plastic wet material, and performing extrusion-spheronization balling, drying and calcining to obtain regular spherical adsorbent particles. The formed adsorbent prepared through the method has the advantages of being controllable in particle size, high in mechanical strength, good in adsorptive property after being formed, excellent in cycling stability and the like, can be used for CO2 chemical adsorption trapping of CO2-containing gas under the medium-temperature condition, and is good in CO2 adsorptive property, economical efficiency of the technological method and environmental protection performance, the process technology is easy to amplify, and the method is suitable for industrial production. The method is suitable for industrial large-scale production.
Owner:ZHEJIANG UNIV OF TECH

An extrusion blow molded article having high rigidity and a method of making the same

The application discloses an extrusion blow molding product with high rigidity and a preparation method thereof, and relates to the technical field of packaging materials. The extrusion blow molding product comprises the following components in percentage by weight: bimodal polyethylene 25-85%, unimodal polyethylene 15-75%. The application effectively improves the technical defects of narrow temperature window, uneven wall thickness, melt easy sagging, blow breaking, large flash and the need to reform the bottle blowing equipment when using bimodal polyethylene alone by blending bimodal polyethylene with unimodal polyethylene and adjusting the blow molding process. Meanwhile, the high rigidity of bimodal polyethylene is retained, the compression strength of the prepared blow molding product can be increased by 20% at most compared with the unimodal polyethylene product, the product weight per unit area is reduced by 7-8%, and the raw material cost can be greatly reduced.
Owner:GUANGZHOU LIBAI TECH GRP CO LTD

Energy-saving drying equipment for compound fertilizer production

The utility model discloses an energy -saving compound fertilizer production is with drying equipment, including fixed bolster and transverse installation's drying pipeline, and the both sides of pipeline are equipped with inlet pipe and discharge pipe respectively, is equipped with conveying device inside, and the top is linked with the heat supply device below through hot gas delivery structure, and the inner wall of drying pipeline is coated heat -proof coating and reduces heat loss, and the electric butterfly valve at inlet pipe place can accurate control feed quantity, and the guide vane of discharge pipe is convenient for material discharge. Conveying device adopts the spiral structure with wear -resisting ceramic coating, prolongs the life, and hot gas delivery fan is frequency conversion formula, and heat supply device is equipped with automatic temperature control system, can adjust hot gas delivery capacity and temperature according to need, and main conveying pipeline is wrapped with heat -insulating cotton and reduces heat loss. Besides, the equipment guarantees the leakproofness through graphite sealing washer, and the stability is promoted to the damping rubber block of bearing seat, and the anti -skid cat ladder of fixed bolster guarantees the operation safety, effectively improves energy utilization efficiency and production safety.
Owner:广东福利龙复合肥有限公司

Aluminum beryllium enhanced high-conductivity heat-resistant aluminum alloy material and preparation method thereof

The invention discloses an aluminum beryllium enhanced high-conductivity heat-resistant aluminum alloy material and a preparation method thereof, and belongs to the technical field of metallurgical wire rod processing. The aluminum beryllium enhanced high-conductivity heat-resistant aluminum alloy material is prepared from the following components in percentage by weight: 0.12 to 0.16 percent of Si, 0.15 to 0.35 percent of Fe, 0.005 to 0.10 percent of Cu, 0.35 to 0.85 percent of Zr, 0.2 to 0.45 percent of Y, 0.15 to 0.35 percent of Er, 0.005 to 0.03 percent of B, 0.001 to 0.02 percent of Ti, 0.03 to 0.05 percent of Be, less than or equal to 0.5 percent of other impurities and the balance of Al. According to the aluminum alloy single wire, the specific raw material composition is adopted, namely, multiple elements such as Zr, Y, Er and Be are compositely added, and the proportion of the elements is strictly controlled, so that the prepared aluminum alloy single wire achieves synergistic improvement of high strength, high conductivity and excellent heat resistance.
Owner:TEBEN ELECTRICAL EQUIPMENT GROUP CO LTD +1

Blending process of hemp fiber and Sorona fiber

PendingCN122128847AImprove spinnabilityMeet the needs of useYarnPolymer scienceNatural fiber
This invention relates to a blending process for hemp fiber and sorona fiber, belonging to the technical field of blending and processing of natural fibers and bio-based elastic fibers. The blending process for hemp fiber and sorona fiber of this invention includes the following steps: raw material selection → pre-spinning process → post-spinning process → packaging. This invention solves the problems of poor spinnability, high breakage rate, and stiffness and wrinkling in pure wet-spun hemp through specific proportions and wet spinning processes, achieving high-count, stable, and high-quality production. This significantly improves spinnability, enhances yarn quality, and greatly improves hand feel and comfort, achieving high elasticity and comfort to meet user needs.
Owner:ZHEJIANG JINYUAN FLAX

Full-period drainage and mining method suitable for low-pressure low-yield shale gas horizontal well

According to the full-period drainage and mining method suitable for the low-pressure and low-yield shale gas horizontal well, the mode of'coiled tubing and electric submersible pump 'in the initial stage is adopted to rapidly drain accumulated liquid in a shaft, the flowback rate is increased, and efficient gas testing is achieved; the liquid carrying capacity of the gas well is improved in a middle-stage pipe column optimization and'pipe column optimization + 'composite drainage and production mode, and stable production of the gas well is facilitated; according to the method, the design is reasonable, the application range is wide, operation is convenient, the measure construction period is shortened, and efficient production of the low-pressure and low-yield shale gas horizontal well can be achieved.
Owner:CHINA PETROLEUM & CHEMICAL CORP +1

Food packaging bag raw material conveying structure

ActiveCN224408142Uincrease profitless cost increaseProcess engineeringFood packaging
The application discloses a food packaging bag raw material conveying structure and relates to the field of food packaging bags, which comprises a conveying cavity, one end of the conveying cavity is provided with an inspection plate, one end of the inspection plate is provided with an output device, the output end of the output device is in transmission connection with one end of an auger, the auger is rotationally connected to one end of the inspection plate, the top end of the conveying cavity is provided with an inlet, and a screening structure is arranged in the inlet. In the application, the plastic particles required to be transmitted to the food packaging bag production equipment can be screened according to requirements, and the plastic particles that do not meet the standards can be treated until the size meets the standards. In this way, the utilization rate of raw materials is improved, the cost increase caused by material waste is reduced, and the uniform particles are easier to control parameters in processing, so that the production process is more stable.
Owner:上海上源印务有限公司

Method and system for depicting water invasion dominant channel space of fractured-porous gas reservoir

PendingCN121995530AImprove the shortcomings of identification methodsAccurate judgmentDesign optimisation/simulationProbabilistic CADSoil scienceReservoir water
The invention belongs to the technical field of gas reservoir exploration, and particularly relates to a method and a system for depicting a water invasion dominant channel space of a fractured-porous gas reservoir. The method comprises the following steps: establishing a dual-medium fine geological model, wherein the dual-medium fine geological model comprises a matrix porosity model and a discrete fracture network model; obtaining a matrix permeability model according to the matrix porosity model, and obtaining a fracture permeability model according to the discrete fracture network model; matrix heterogeneity characterization parameter gridding is carried out based on the matrix permeability model, and fracture heterogeneity characterization parameter gridding is carried out based on the fracture permeability model. According to the method, the near-wellbore zone water invasion channel or the seepage barrier can be accurately judged, the whole gas reservoir water invasion channel or the area to be subjected to water invasion can be predicted, the influence of human factors is reduced, and the method is visual, fine, high in calculation efficiency and high in accuracy for the crack-pore type reservoir. And predicting the geometrical morphology and spatial configuration relation of the water invasion channel with comprehensive evaluation parameters.
Owner:CHINA NAT PETROLEUM CORP +3

Meta-aramid fibrid and preparation method thereof

The invention discloses meta-aramid fibrid and a preparation method thereof, the meta-aramid fibrid comprises, by dry weight, 90.0-99.5 wt% of meta-aramid resin and 0.5-10.0 wt% of an amphiphilic block copolymer additive, and the additive comprises at least one of p-N-methyl pyrrolidone or N, N-dimethyl pyrrolidone or N, N-dimethyl pyrrolidone or N, N-dimethyl pyrrolidone or N, N-dimethyl pyrrolidone or N, N-dimethyl pyrrolidone or N, N-dimethyl pyrrolidone or N, N-dimethyl pyrrolidone or N, N-dimethyl pyrrolidone or N, N-dimethyl pyrrolidone. A first block having an affinity for N, N-dimethylacetamide; and at least one second block having an affinity for water. The preparation method comprises the following steps: adding an additive into a meta-aramid resin polymerization liquid to form a composite resin polymerization liquid; injecting the composite liquid into a precipitation bath composed of N-methyl pyrrolidone or N, N-dimethylacetamide and water through a dispersing device, and after precipitation, carrying out solid-liquid separation, washing and drying to obtain the fibrid. Through the synergistic effect of a specific additive and a precipitation bath system, the microstructure of the fibers is actively regulated and controlled, and the specific surface area and the surface roughness of the fibers are improved, so that the tensile strength and the internal bonding strength of finished paper are remarkably enhanced, and meanwhile, the inherent high-temperature-resistant, flame-retardant and insulating properties of meta-aramid fibers are kept.
Owner:WUJIANG YAXIMA TEXTILE CO LTD

A flybar hook member dedicated to a package substrate

ActiveCN224411956UEasy to fixSimplify fixityProduction lineScrew thread
The utility model provides a kind of flybar hook component special for packaging substrate, and "7" shape is constituted by connecting hook and fixed base plate through vertical connecting rod, hook is composed of first vertical section, second vertical section and horizontal connecting section, and first vertical section connects vertical rod.Flybar fixing assembly of hook contains first screwing screw, threaded hole and spring piece.Fixed base plate contains base plate ontology, at least one second screwing screw and threaded hole, can firmly fix backlight sheet, solve the problems of inconvenient operation, position inflexibility and poor monitoring of existing flybar hook component special for packaging substrate.Its detachable structure makes backlight sheet installation and disassembly convenient, improves efficiency.Precise fixing backlight sheet in flybar middle, simulates actual environment, monitoring is more real, it is convenient to find problem, improves product quality and consistency.In addition, the hook can also fix various production materials, has universality, reduces production cost, reduces interruption and quality problem, improves the stability and reliability of VPTH production line.
Owner:SHANGHAI MEADVILLE SCI & TECH

Multi-roll oiling device and use thereof

The application belongs to the technical field of chemical fiber and textile, and discloses a multi-roller oiling device and application thereof. The multi-roller oiling device comprises an oil nozzle, an oiling pump, a first oil roller, a second oil roller and a skin pressing roller which are located in the wire passing channel of the oil nozzle. The second oil roller is located below the first oil roller, the rightmost sides of the two are located on the same vertical plane and are located on the right side of the left side wall, and the rotating directions of the two are the same. The skin pressing roller is located on the right side of the second oil roller, a gap is left between the two, and the rotating directions of the two are opposite. The left side wall of the oil nozzle is provided with an oil inlet and an oil outlet, the upper surface of the protruding part of the oil nozzle is provided with a C-shaped groove connected with the oil outlet, and the first oil roller is embedded in the C-shaped groove. The cross section of the first oil roller is composed of a center circle and a plurality of C-shaped lines. The preparation method of the profiled fiber is as follows: polyester melt extrusion, cooling and forming, oiling and winding and forming. The quality and efficiency of the preparation of the profiled fiber are improved.
Owner:JIANGSU DELI CHEM FIBER CO LTD

Recombinant genetically engineered bacterium of yarrowia lipolytica as well as construction method and application of recombinant genetically engineered bacterium

The invention relates to the technical field of microorganisms, in particular to recombinant genetically engineered bacteria of yarrowia lipolytica as well as a construction method and application of the recombinant genetically engineered bacteria. The succinic acid production performance of the recombinant genetically engineered bacterium of yarrowia lipolytica is remarkably improved, high succinic acid yield and production intensity are achieved, the recombinant genetically engineered bacterium can be applied to stable and efficient production of succinic acid, the performance of the recombinant genetically engineered bacterium is stable, and the recombinant genetically engineered bacterium can be suitable for large-scale industrial production of succinic acid.
Owner:CHINA PETROLEUM & CHEMICAL CORP +1

A catalyst settling system with good running stability and settling effect

The utility model relates to the field of petroleum chemical technology, concretely relates to a catalyst settlement system stable in operation and good in settlement effect, including clarification mechanism, sludge buffer tank, feed pipeline, sludge tank, backflow pipeline, overflow pipeline, filter press, filtrate tank and sludge discharge pipeline, the clarification mechanism includes a plurality of settlement tanks that are arranged side by side from front to back in proper order and the clarification tank that is arranged at the end of clarification mechanism, the bottom of clarification tank is provided with special ammonium sulfate solution discharge pipeline, is provided with ammonium sulfate solution pump on the ammonium sulfate solution discharge pipeline, the end of ammonium sulfate solution discharge pipeline extends to ammonium sulfate tank area, the outlet end of ammonium sulfate solution pump is equipped with a branch pipeline, this branch pipeline is connected with the feed inlet on the top of filtrate tank through regulating valve, the bottom outlet of filtrate tank is connected with the inlet of clarification mechanism through filtrate pump. The catalyst settlement system is stable in operation, and the downstream device operation cycle is prolonged.
Owner:LIHUA YIHUIHAI NEW MATERIALS (LIJIN) CO LTD

A spinneret

ActiveCN224411973Ubalanced productionefficient production
The utility model provides a kind of spinneret, belong to textile machinery technical field.Its structure includes: a plurality of shunt cone is arranged to form array in the upper end of spinneret body, the shape of the array is regular hexagon, there are a plurality of spinneret hole in the periphery of each shunt cone;Every two adjacent shunt cone is arranged at equal intervals;Every two adjacent spinneret hole is arranged at equal intervals.The utility model is designed with new structure, can optimize the spinning process of fiber, improve the dispersion uniformity and surface quality of fiber.Through the structure design and material selection of spinneret, realize efficient, stable fiber production.The spinneret includes spinneret body and multiple spinneret holes arranged on the spinneret body.The shape, size and arrangement of spinneret hole are carefully designed to achieve uniform dispersion of fiber.At the same time, spinneret body is made of high-temperature-resistant and wear-resistant material to ensure stability in high temperature and high pressure environment.
Owner:BEIJING DONGCHEN RUIFENG CHEM

Gelled cell as well as preparation method and application thereof

The invention discloses a gelled cell as well as a preparation method and application thereof. Relates to the field of synthetic biology and biomedicine. The gelated cell is a cell structure without cell viability, and comprises: a carrier cell framework comprising a cell membrane which retains the membrane protein content, the type and the lipid order of an original carrier cell; the intracellular hydrogel is formed in situ in the carrier cell framework through supramolecular host-guest interaction or cross-linking reaction, and is fused with the inner surface of a cell membrane; the antibacterial substance is loaded in the intracellular hydrogel; wherein pores are distributed on the cell membrane, the intracellular hydrogel is communicated with the external environment through the pores, and the loaded antibacterial substances are exposed. The gelated cell provided by the invention can simultaneously realize targeted delivery, contact sterilization and endotoxin adsorption, and avoids the problem of secondary inflammation caused by release of endotoxin in traditional antibiotic therapy and the problem of membrane protein loss or disordered arrangement in a cell membrane coating technology.
Owner:SHENZHEN UNIV

A rolling process for eliminating flaw detection noise of high-strength aluminum alloy plate with low alloy content

This invention provides a rolling process for eliminating noise during flaw detection of high-strength aluminum alloy sheets with low alloy content. The process employs a three-stage homogenization heat treatment: heating at 40℃ / h to 400-405℃ and holding for 3 hours; heating at 40℃ / h to 445-460℃ and holding for 10-24 hours; heating at 10℃ / h to 492-496℃ and holding for 8-24 hours; and then rolling at 420℃. The rolling process uses 9-15 passes, with the first three passes being rapid rolling and the last three passes using a large reduction (greater than 17% reduction per pass) for rapid rolling. The middle passes use a large reduction for rapid rolling, while the remaining passes use a small reduction for slow rolling. The final rolling temperature is not lower than 410℃. The thick plates obtained by this rolling process have a uniform microstructure along the thickness direction, small grain size, pass non-destructive testing, and possess high strength, plasticity, and fracture toughness.
Owner:SHANDONG NANSHAN ALUMINUM +1

Anti-gcdfp-15 monoclonal antibodies, methods of making and uses thereof

PendingCN122587067Aavoid risk factorsImprove stability
The application relates to an anti-GCDFP-15 monoclonal antibody and a preparation method and application thereof, and belongs to the technical field of immunology. The anti-GCDFP-15 monoclonal antibody provided by the application has the amino acid sequence of a heavy chain variable region as shown in SEQ ID NO. 1 and the amino acid sequence of a light chain variable region as shown in SEQ ID NO. 2. The nucleotide sequences of the heavy chain variable region and the light chain variable region of the monoclonal antibody are also provided, and the monoclonal antibody can be prepared by using genetic engineering technology. The monoclonal antibody prepared by the application has the advantages of stable property, high experimental repeatability and high titer, is suitable for immunological detection, and can specifically recognize the GCDFP-15 protein expressed in human skin and breast tissue.
Owner:SINOTECH BIOTECHNOLOGY (SUZHOU) CO LTD +1

A process for the production of a clotrimazole intermediate (2-chlorophenyl)diphenylmethanol

ActiveCN117623865BNot easy to formAcid and base stableOrganic compound preparationHydroxy compound separation/purificationDiphenylmethanolBenzoic acid
The application belongs to the technical field of medical intermediates, and relates to a production method of a clotrimazole intermediate (2-chlorophenyl)diphenylmethanol. In the method, 2-methyltetrahydrofuran or cyclopentyl methyl ether is used as a reaction solvent, an ethyl o-chlorobenzoate solution is added dropwise into a phenyl magnesium bromide solution with a concentration of 2.5-3.5 M under the conditions of 60-80 DEG C and inert atmosphere, the reaction is continuously carried out after the dropwise addition is completed, a water solution of a quenching agent is added after the reaction to quench, then, liquid separation is carried out, and the organic phase after the liquid separation is concentrated to obtain a crude product; the crude product is refined by using a reaction solvent and petroleum ether, and (2-chlorophenyl)diphenylmethanol is obtained. The production method can efficiently and stably produce high-quality (2-chlorophenyl)diphenylmethanol, reduces production cost and safety hazards, and can be used for large-scale industrial production.
Owner:SHANDONG KEXIN PHARM CO LTD

Method for adding simulation function to DCS analog quantity template

PendingCN122197246Aavoid failureAdd simulation functionDesign optimisation/simulation
The present application relates to papermaking technical field, specifically to a kind of method for increasing simulation function of DCS analog template, comprising the following steps: S1: simulation value variable and physical address numerical variable selection;S2: simulation value variable range limit, manually input value in the range of the corresponding field device range;S3: simulation value variable is converted to 0-10000 range of numerical value according to engineering range by CIP arithmetic operation instruction, then 0-10000 range numerical variable is transmitted to original program physical address setting;S4: picture setting: simulation enable, simulation mode and simulation value input;S5: simulation mode permission user setting.The present application increases simulation function, optimizes system, facilitates debugging and maintenance equipment, meets production continuous requirement, stable production, avoids the failure of field signal or equipment maintenance, chain trip, this method is to increase simulation function on the basis of original analog quantity control module, simulation value can be input manually through DCS, reduce downtime, or the influence of maintenance instrument.
Owner:DONGGUAN JINZHOU PAPER IND

Method and device for acoustically monitoring the operating state of a catalytic cracking unit

This invention provides an acoustic monitoring method and device for the operating status of a catalytic cracking unit. The catalytic cracking unit includes a multi-stage wing valve, each stage comprising multiple wing valves. The method includes: acquiring acoustic signals of the wing valves during a certain operating time; performing data preprocessing on the acoustic signals to obtain processed acoustic signals; determining the flow rate percentage of each wing valve during the operating time based on the processed acoustic signals; and determining the operating status of the wing valves during the operating time based on the flow rate percentages of the wing valves. The operating status of the wing valves during the operating time is used to characterize the operating status of the catalytic cracking unit. The acoustic monitoring method and device for the operating status of the catalytic cracking unit of this invention have the advantage of accurately determining the operating status of the wing valves through the flow rate percentages of each wing valve, thereby guiding the adjustment of process parameters of the catalytic cracking unit, providing a basis for production operation, and enabling the catalytic cracking unit to maintain stable production.
Owner:CHINA PETROLEUM & CHEMICAL CORP +1