280 results about "Cell processing" patented technology

The present disclosure relates to systems, devices, and methods for conditional execution within a cell processing system. In an embodiment, the present disclosure relates to a method of automatically executing a pre-programmed workflow defining a set of cell processing steps, determining whether a condition has been met based upon at least one measured parameter, and continuing, modifying, or stopping the workflow based upon the determination.

The present disclosure relates to systems, devices, and methods for automated fluid control within a cell processing system. In an embodiment, the present disclosure relates to a cartridge having a fluidic manifold comprising a first end panel, a second end panel, and a central panel connecting the first and second end panels, where each of the first and second end panels comprises a plurality of fluidic pathways model therein and a plurality of valves for controlling fluid flow through the plurality of fluidic pathways.

The present disclosure relates to systems, devices, and methods for automated cell sorting within a cell processing system. In an embodiment, the present disclosure relates to an automated cell sorting system comprising a cartridge having a cell sorting module, where the cell sorting module comprises a flow cell, and an instrument within a bay of a cell processing workcell, where the instrument comprises a magnetic array couplable to the flow cell, each of the magnets within the magnetic array having a width of w and being spaced apart by between about w / 3 to about 3 / 4w, and wherein the flow cell has a height of between about 1 / 12w to about 1 / 8w.

The present disclosure relates to systems, devices, and methods for conditional execution within a cell processing system. In an embodiment, the present disclosure relates to a method of automatically executing a pre-programmed workflow defining a set of cell processing steps, determining whether a condition has been met based upon at least one measured parameter, and continuing, modifying, or stopping the workflow based upon the determination.

The present disclosure relates to systems, devices, and methods for automated cell processing within a cell processing system. In an embodiment, the present disclosure relates to a cartridge comprising a bioreactor module comprising a bioreactor, a first thermal compartment positioned adjacent the bioreactor, and a second thermal compartment positioned adjacent the bioreactor, and a fluidic manifold coupling the first and second thermal compartments to the bioreactor.

The present disclosure relates to systems, devices, and methods for automated fluid control within a cell processing system. In an embodiment, the present disclosure relates to a cartridge having a fluidic manifold comprising a first end panel, a second end panel, and a central panel connecting the first and second end panels, where each of the first and second end panels comprises a plurality of fluidic pathways model therein and a plurality of valves for controlling fluid flow through the plurality of fluidic pathways.

The present disclosure relates to systems, devices, and methods for automated fluid control within a cell processing system. In an embodiment, the present disclosure relates to a cartridge having a fluidic manifold comprising a first end panel, a second end panel, and a central panel connecting the first and second end panels, where each of the first and second end panels comprises a plurality of fluidic pathways model therein and a plurality of valves for controlling fluid flow through the plurality of fluidic pathways.

Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

The present disclosure relates to systems, devices, and methods for controlling fluid flow within a cell processing system. In an embodiment, the present disclosure relates to a device having a rotor comprising one or more rollers configured to compress a first fluid conduit, a first lever arm defining a proximal portion and a distal portion, where the first lever arm comprises a first hinge at the proximal portion, and a second hinge in between the proximal portion and the distal portion, a spring coupled to the distal portion, and a second lever arm, where the first and second lever arms are aligned with the rotor and are configured to receive the first fluid conduit.

Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

The present application relates to the technical field of battery production, and provides a smart production line for a cylindrical cell, comprising, successively arranged in a processing direction, a cell loading station, a cathode current collector welding station, a cathode coating station, a cell in-casing station, a cathode post welding station, an anode current collector welding station, a current collector lateral welding station, a cover plate tack welding station, a cover plate seal welding station, a cell unloading station and a cell transfer mechanism. The present application reasonably distributes each processing station to more reasonably process and produce cells and, during the entire production process, the stations can cooperate with each other to efficiently complete production and effectively improve the yield and the degree of automation during the cylindrical cell processing procedures, reducing cylindrical cell production costs.

The present disclosure relates to systems, devices, and methods for electroporating. In an embodiment, the present disclosure relates to an electroporation system, comprising at least one electroporation chamber, each electroporation chamber comprising a first electrode and a second electrode, a plurality of ports comprising an inlet port at a first portion of each electroporation chamber, and an outlet port at a second portion of each electroporation chamber, a fluid conduit arranged between the first electrode and the second electrode, the fluid conduit being in fluid communication with the inlet port and the outlet port, and an automated system for electroporation operatively connected to the first electrode and the second electrode of the at least one electroporation chamber.

The present disclosure relates to systems, devices, and methods for automated cell processing within a cell processing system. In an embodiment, the present disclosure relates to a cartridge comprising a bioreactor module comprising a bioreactor, a first thermal compartment positioned adjacent the bioreactor, and a second thermal compartment positioned adjacent the bioreactor, and a fluidic manifold coupling the first and second thermal compartments to the bioreactor.

The present disclosure relates to systems, devices, and methods for automated cell sorting within a cell processing system. In an embodiment, the present disclosure relates to an automated cell sorting system comprising a cartridge having a cell sorting module, where the cell sorting module comprises a flow cell, and an instrument within a bay of a cell processing workcell, where the instrument comprises a magnetic array couplable to the flow cell, each of the magnets within the magnetic array having a width of w and being spaced apart by between about w / 3 to about 3 / 4w, and wherein the flow cell has a height of between about 1 / 12w to about 1 / 8w.

The present disclosure relates to systems, devices, and methods for spinoculation and counterflow centrifugal elutriation. In an embodiment, the present disclosure relates to a cartridge in an automated system, comprising a liquid transfer bus, a module fluidically coupled to the liquid transfer bus, the module comprising two sub-modules, each configured to perform separate cell processing steps, and at least one selector valve configured to direct fluid to at least one of the sub-modules.

Disclosed herein are cell processing systems, devices, and methods thereof. A system for cell processing may comprise a plurality of instruments each independently configured to perform one or more cell processing operations upon a cartridge, and a robot capable of moving the cartridge between each of the plurality of instruments.

The invention relates to the technical field of lithium cell spot welding, and particularly discloses a spot welding device for lithium cell processing and production, which comprises a workbench, a working frame is fixed on the top of the workbench, a moving frame is arranged on the surface of the working frame, a spot welding head is arranged on the surface of the moving frame, and a cell part is arranged on the top of the workbench. Connecting sheets are uniformly distributed at the top of the battery core piece; the device further comprises a placing assembly and a weight monitoring part, the placing assembly is arranged on the surface of the workbench, the number of the battery cells is judged by monitoring the weight of the battery cells, the purpose of monitoring the number of the battery cells is achieved, the advancing direction and position of the spot welding head are detected in advance through the pressure monitoring part, and monitoring of the spot welding direction of single-row and double-row battery packs is facilitated; manual direction observation and an intelligent numerical control mode are replaced, stability and simplicity are achieved, meanwhile, the spot welding pressure needed by the spot welding head is judged according to the thickness, monitored by the abutting base, of the connecting piece, and current can penetrate through materials to enable the welding portion to reach the needed melting temperature.

The utility model discloses a laminated battery cell and preparation equipment thereof, the laminated battery cell is prepared by folding a battery cell structure, the battery cell structure comprises a first pole piece, a diaphragm and a second pole piece, the first pole piece is located on one side of the diaphragm, and the first pole piece is connected with the diaphragm through a normal-temperature normal-pressure conductive adhesive; and the second pole pieces are alternately arranged on the sides, away from the first pole pieces, of the diaphragms, and the second pole pieces are connected with the diaphragms through normal-temperature and normal-pressure conductive adhesives. The normal-temperature and normal-pressure conductive adhesive disclosed by the utility model has relatively good adhesion performance at normal temperature and normal pressure, and also has relatively good conductivity, so that the problem of poor battery performance caused by high-temperature and high-pressure thermal compounding of a pole piece and a diaphragm in the existing laminated cell processing process is solved, the condition of poor liquid absorption effect and interface of the battery is improved, and the service life of the battery is prolonged. And the battery performance is improved.

The utility model discloses a cell clamping mechanism and a cell processing device, the cell clamping mechanism comprises a frame, a clamping assembly and a support piece, the clamping assembly is installed on the frame, the clamping assembly comprises two upper clamping arms and two lower clamping arms, one upper clamping arm is correspondingly arranged above the lower clamping arm, and the other upper clamping arm is correspondingly arranged above the lower clamping arm. The two upper clamping arms and the two lower clamping arms can move relatively so as to clamp or loosen the two ends of the battery cell; and the supporting piece is connected to the clamping assembly and is positioned between the two lower clamping arms so as to support the middle part of the battery cell. According to the technical scheme, the battery cell clamping mechanism can clamp the two ends of the battery cell through the clamping arms on the two sides respectively, the middle of the battery cell is supported through the supporting piece, and the situation that the middle of the battery cell is bent due to the gravity effect, and then the position precision of the battery cell is affected is avoided; the problem that positive plates, negative plates and diaphragms which are stacked in a battery cell are slightly staggered is solved, rapid and stable grabbing and placing can be achieved, the carrying efficiency is improved, and the subsequent processing quality is guaranteed.

The present disclosure relates to systems and methods for monitoring pressure during automated cell processing. An illustrative method for monitoring pressure within a fluid device of an automated cell processing system includes coupling a fluid device having an air vent to a cell processing instrument. Next, the method includes transferring liquid between the fluid device and the instrument, determining a liquid transfer rate between the fluid device and instrument and an airflow rate through the air vent of the fluid device, and estimating an internal pressure of the fluid device based on the airflow rate and the liquid transfer rate. The fluid device may be a liquid transfer device, the instrument may be a liquid transfer instrument, and the system may facilitate liquid transfer between the liquid transfer device and a cell processing cartridge via the liquid transfer instrument.

The present disclosure relates to systems, devices, and methods for automated fluid transfer. In an embodiment, the present disclosure relates to a system for fluid transfer between a fluid device and a cartridge for cell processing. The system comprises a first portion comprising an instrument head coupled to a gantry, the instrument head comprising a pneumatic actuator, a peristaltic pump, and a gripping feature for receiving the fluid device. The peristaltic pump may be configured to engage compressible fluidic tubing of a fluid pump module of the fluid device to transfer the fluid between the fluid device and the cartridge. The system further comprises a second portion comprising a docking station for receiving the cartridge. In some variations, movement of the pneumatic actuator relative to the fluid pump module causes occlusion of the compressible fluidic tubing of the fluid pump module by the peristaltic pump.

The utility model relates to the technical field of battery production, in particular to a battery cell pre-welding and cutting magnetic suspension production line and a battery production system. The battery cell pre-welding and cutting magnetic suspension production line comprises a magnetic suspension conveying assembly, a feeding assembly, a tab welding assembly, a tab cutting assembly, a rubberizing assembly and a discharging assembly. The magnetic suspension conveying assembly comprises a conveying line and a plurality of rotor carriers, the feeding assembly, the tab welding assembly, the tab cutting assembly, the rubberizing assembly and the discharging assembly are sequentially arranged at intervals in the conveying direction of the conveying line so as to form a plurality of cell processing stations on the conveying line, and the rotor carriers circularly move on the conveying line; and the battery cells are driven to shuttle to different battery cell processing stations along the conveying direction of the conveying line. The magnetic suspension conveying assembly replaces a traditional conveying mode, the rotor carrier flows back smoothly, the conveying time is saved, the automation degree is high, personnel investment is reduced, the occupied area is small, and the conveying efficiency between stations of the battery assembly line is effectively improved.

The invention discloses a ZYNQ series FPGA self-repairing structure based on a self-adaptive redundancy strategy, which comprises a logic end and a processor end, the logic end and the processor end perform signal interaction through an AXI bus, and a PCAP interface is adopted to complete the configuration of the logic end. The logic end is divided into a plurality of logic function areas, and each area comprises three identical function cells and an interconnection cell. And the processor end comprises a self-repairing controller, a fault responder, a read-back refreshing controller and an external memory DDR (Double Data Rate). The invention provides a ZYNQ self-repairing design method based on the structure, functional cells can change redundancy modes according to different radiation environments, detection and repairing of cell-level and molecular-level faults are achieved, reliability and flexibility of operation of a ZYNQ series FPGA system are improved, and therefore the universal ZYNQ self-repairing design method is provided for design and development personnel.

According to various examples, a radio access network controller is described comprising a processor configured to determine whether a mobile terminal is located at a center region of a radio cell of a communication network or an edge region of the radio cell, and control the communication network to serve the mobile terminal by a plurality of radio units of a plurality of radio cells using coherent joint transmission by allocating the same time, frequency, code and spatial resources, if the processor determines that the mobile terminal is in the edge region of the radio cell and control the communication network to serve the mobile terminal by one radio unit of the radio cell using single-cell processing if the processor determines that the mobile terminal is in the center region of the radio cell.

The invention belongs to the technical field of biology, and discloses a micro-fluidic chip for in-situ single-cell non-label imaging of an upright Raman microscope. Comprising a quartz substrate subjected to surface treatment, a detachable cell chamber, a glass sheet provided with a through hole and a gravity flow channel control system, the cell chamber is used for cell culture before in-situ cell imaging, after cell culture is completed, the cell chamber is taken off, the glass sheet is bonded with the quartz substrate, the glass sheet is used for packaging a chip, and the gravity flow channel control system is used for controlling the gravity flow channel. The gravity flow channel control system is connected with the through hole and is used for guiding fluid to flow in the chip; the micro-fluidic chip can effectively package living cells and is compatible with a forward Raman microscope, so that in-situ unlabeled Raman imaging of single cells under the microscope is realized, experimental operation is simplified, more efficient cell treatment and real-time monitoring capabilities are provided, imaging stability and accuracy are improved, and the micro-fluidic chip is suitable for large-scale popularization and application. The method is of great significance to application of drug screening, biochemical research and the like.

The present invention provides: a package for aseptically preparing many kinds of substances and containers for a cell processing device and reducing workload of mutually connecting the containers; a cell manufacturing method using the same; and a management system for manufacturing the package.

The invention discloses a cell processing method and device, a terminal, network side equipment and a readable storage medium, and belongs to the technical field of communication, and the cell processing method comprises at least one of the following steps: the terminal executes cell selection or cell reselection according to first priority information; the terminal requests the network side equipment to update a target cell of the terminal to a second cell in which the terminal resides currently, wherein the target cell is a cell which receives the radio resource control release message for the last time; wherein the first priority information is used for representing at least one of the following: the priority of the target cell of the terminal is highest; the frequency point where the target cell of the terminal is located has the highest priority; the terminal satisfies at least one of the following items: supporting to monitor a wake-up signal; the monitor is configured to monitor a wake-up signal.

The invention relates to a method for controlling a single cell and a single liquid drop based on light, which realizes capture of a target single cell and export of the single liquid drop on a micro-fluidic chip by combining an optical tweezers technology and a photoinduced bubble technology, and comprises the following steps: introducing a sample to be detected into a main channel of the micro-fluidic chip; using an optical tweezers technology to control a target single cell and dragging the target single cell into a side chamber; excluding non-target single cells; replacing liquid to treat the target single cell; a target product forms a single liquid drop by utilizing a photoinduced bubble technology and is guided out. The technical problems that in the prior art, single cells and single liquid drops cannot be accurately controlled at the same time, and separation and culture of intracellular bacteria cannot be achieved are solved.

The structural formula of the sodium ion battery positive electrode material is NaxFey (PO4) 2P2O7, x is more than or equal to 3.92 and less than or equal to 4.2, y is more than or equal to 2.8 and less than or equal to 3, and x-y is more than or equal to 1.1 and less than or equal to 1.4. The preparation method comprises the following steps: calcining a precursor and then cooling, or calcining the precursor and then quenching, or heating and calcining the precursor and then quenching and tempering; and S2, crushing the semi-finished product obtained by sintering in the step S1. The sintering method of the sodium ferric phosphate pyrophosphate is substantially improved, the heating-cooling process is controlled, the structure of the positive electrode material is improved, the structural formula of the positive electrode material is controlled to be NaxFey (PO4) 2P2O7, 3.92 < = x < = 4.2, 2.8 < = y < = 3 and 1.1 < = x-y < = 1.4, the tap density and the specific capacity of the sodium ferric phosphate pyrophosphate are improved, and the sodium ferric phosphate pyrophosphate has more excellent cell processing performance.