593 results about "Humans tissues" patented technology

Systems and methods herein generally relate to prolonging viability of bodily tissue, especially an organ such as a lung, by adjusting pressure as needed to maintain a constant pressure within the organ even during external pressure fluctuations due, for example, to transportation of the organ in an airplane. The systems and methods herein can include an electronic pump that pumps gas into an organ and a mechanical pressure regulator to release gas based on organ pressure.

This document generally describes methods and systems for generating digital reconstructions of tissue from humans or other species. The method can, for example, include receiving, at a computing system, image data of a tissue sample, where one or more sections of the tissue sample are stained with hematoxylin and eosin (H&E), registering the image data to generate registered image data, identifying tissue subtypes based on application of a machine learning model to the registered image data, annotating the identified tissue subtypes to generate annotated image data, and determining a digital volume of the tissue sample in three dimensional (3D) space based on the annotated image data. The disclosed technology can provide for single-cell analysis and other analysis of tissue samples, such as early detection of cancer in human tissue samples.

The invention discloses a PD-L1 immunohistochemical quality control product and a preparation method thereof, and relates to the technical field of biology. The PD-L1 immunohistochemical quality control product comprises cell slices prepared from a plurality of different types of tumor cells, the cell section comprises a positive quality control product and a negative quality control product which are marked by different colors. In the invention, different tumor cells are creatively adopted as raw materials of the quality control product, the quality control product can be efficiently and quickly prepared, and the limitation of the source of a human tissue sample is overcome; a BSA sealing buffer solution is used for soaking the section, so that long-term stable production of a quality control product can be realized, the dyeing background is reduced, and the dyeing effect is enhanced; besides, by preparing the cell slices with various proportions and different staining intensities, the quality control on the staining of the antibody can be ensured, and guidance can also be provided for accurate interpretation, namely comprehensive and accurate quality control and interpretation guidance are provided for the staining of the antibody, false negative and false positive are effectively eliminated, and the method has great clinical significance.

The invention relates to a pulmonary nodule minimally invasive needle biopsy excision device, and relates to the technical field of medical instruments. The system comprises a mechanical arm electrically connected with CT equipment, navigation auxiliary equipment, a puncture assembly detachably connected with the mechanical arm and used for puncturing human tissue, a sampling assembly for sampling tissue at a nodule and a marking assembly for marking the sampling position; the puncture assembly comprises a mounting base detachably connected with the mechanical arm and a puncture needle arranged on the mounting base, and the end of the puncture needle is sharp. The puncture needle is arranged in a hollow mode, the sampling assembly comprises a rotary cutting cylinder rotationally arranged in the puncture needle and a power part for driving the rotary cutting cylinder to rotate, a first rotary cutting opening is formed in the puncture needle, a second rotary cutting opening is formed in the rotary cutting cylinder, and the first rotary cutting opening movably corresponds to the second rotary cutting opening. The biopsy sampling device has the advantages that the sampling amount of each biopsy sampling is conveniently increased, the puncture sampling frequency is reduced, and meanwhile the radiation dosage is reduced.

According to the anastomosis nail releasing device and the suturing device, a driving assembly, a needle pushing plate and a containing cavity used for containing anastomosis nails in the anastomosis nail releasing device are sequentially stacked, that is, the needle pushing plate serves as a boundary, so that structures between the driving assembly and the containing cavity do not interfere with each other, on one hand, no other structures exist in the containing cavity, and on the other hand, no other structures exist in the containing cavity; therefore, the containing cavity can contain larger anastomosis nails, the larger anastomosis nails can penetrate through thick human tissue, even if the containing cavity can contain anastomosis nails of various sizes, the application range of the product is widened, and the product can be applied to more operation scenes. On the other hand, no other structure is arranged in the cavity for installing the driving assembly, so that enough space is provided for installing the driving assembly with a complex structure or a large size, the driving assembly has strong driving force, and the anastomosis nail driven by the driving assembly can more effectively penetrate through the human tissue; therefore, effectiveness and reliability of product sewing are guaranteed.

The invention relates to the technical field of medical apparatuses and instruments, and discloses a biopsy needle which comprises a shell. The near end of the inner needle tube is connected with an inner tube seat, and the inner tube seat is movably arranged in the shell; the inner needle tube is sleeved with the outer needle tube, the near end of the outer needle tube is connected with an outer tube seat, and the outer tube seat is movably arranged in the shell; the rotating mechanism is arranged in the shell and comprises a driving assembly and a transmission assembly in transmission connection with the driving assembly; wherein after the inner tube seat and the outer tube seat are triggered to complete sampling, the inner tube seat and the outer tube seat are both connected with the transmission assembly; by operably driving the rotating mechanism for multiple times, multiple times of synchronous rotation of the inner tube base and the outer tube base can be achieved. According to the biopsy needle provided by the invention, the biopsy needle can be relatively conveniently rotated so as to obtain a target tissue sample thoroughly separated from human tissues, and meanwhile, the range of influence on the human tissues around the target tissue when the biopsy needle is rotated is reduced.

The invention relates to a method for processing medical images of human tissue of an area of a patient's body and in particular of the breast by means of a medical imaging device (1) comprising a microwave probe array consisting of K>1 probes spaced apart from one another, the array comprising P>1 different configurations defining transmitting probes and receiving probes for one or more position(s) around the area, in which the transmitting probes are configured to transmit microwave signals so as to illuminate an area of the body and the receiving probes are configured to receive microwave signals after scattering and reflection in the area, the probes being capable, in a complementary manner, of being configured to transmit and receive simultaneously.

The invention relates to the technical field of anesthesia operation simulation, in particular to an anesthesia operation simulation system based on a VR technology. The system comprises a basic training module, an analysis and evaluation module and a real simulation module. The basic training module simulates a human body model to carry out basic operation training, the analysis and evaluation module establishes an evaluation model of student basic operation by taking operation accuracy, normalization and proficiency as evaluation indexes, and the real simulation module establishes a virtual model of surgical instruments and human body tissues and organs by utilizing a VR technology. Trainees are trained to formulate a reasonable anesthesia scheme according to the illness state, the operation type and the physical condition of a patient and use pathophysiological knowledge to understand and process the illness state change of the patient, personalized feedback is formulated for each trainee according to a training result, and feedback adjustment is performed on basic training and real simulation of the trainees, so that the training efficiency is improved. Therefore, learning and training can be carried out in a more targeted manner, and the learning efficiency is improved.

The invention discloses a far-infrared functional photobiotin composite material, an acupoint patch prepared from the far-infrared functional photobiotin composite material and application of the acupoint patch, and belongs to the technical field of far-infrared medical materials. The photobiotin composite material is prepared from the following components in parts by weight: 25 to 45 parts of modified stone needle, 20 to 30 parts of medical stone, 10 to 20 parts of germanite, 5 to 10 parts of silicon dioxide and 5 to 10 parts of aluminum oxide. The modified stone needle is prepared by processes of bentonite interlayer chambering, LaFe perovskite / TiO2 quantum dot intercalation, Prussian blue analogue loading and the like. The composite material has a far infrared emission characteristic and can generate resonance absorption with human tissues, negative oxygen ions are released through quantum dot photocatalysis, and a porous structure adsorbs inflammatory factors, namely LaFe perovskite / TiO2 quantum dot photocatalysis and cooperates with stone needle far infrared radiation to destroy bacterial cell membranes; and the medical stone releases trace elements to inhibit bacterial activity. The prepared acupoint patch is compounded with a medical pressure-sensitive adhesive through a compression molding process to generate micro-current to stimulate a TRPV1 ion channel, so that the treatment of facial paralysis, hypertension and diabetes mellitus is realized.

The invention discloses an antibacterial breathable dressing patch and a preparation method thereof, and belongs to the field of medical dressings, the antibacterial breathable dressing patch comprises a Janus type dressing patch layer which is a composite film containing a hydrocolloid matrix, pH response antibacterial microspheres and bioactive glass nanoparticles; the super-hydrophobic electrostatic spinning outer layer is a super-hydrophobic electrostatic spinning fiber membrane, and the super-hydrophobic electrostatic spinning outer layer and the Janus type dressing skin-attaching layer are compounded to form an asymmetric Janus structure, intellectualization and precision of the antibacterial effect are achieved, and the risks of cytotoxicity and bacterial drug resistance possibly caused by long-term exposure to an antibacterial agent are reduced to the maximum extent; a multi-mechanism and synergistic antibacterial defense system is constructed, more comprehensive and firm protection is provided for wounds, the air permeability and moisture permeability are excellent, a dry and moist ideal healing environment is created for the wounds, the biocompatibility is good, the use safety is high, the wound healing agent is mild to human tissues, the irritation is low, the allergic reaction risk is small, the safety is high, and the wound healing effect is good. The long-term use is facilitated.

The invention discloses a biological tissue internal temperature microwave chromatography method and system, and belongs to the technical field of microwave measurement. The problem that the internal temperature of the biological tissue cannot be accurately obtained by adopting a microwave radiation temperature measurement technology nowadays is solved. The method comprises the following steps: acquiring environmental thermal radiation rates under different environmental conditions, and acquiring temperature distribution data of a human tissue profile to be subjected to temperature measurement along with depth change under different environmental conditions by utilizing a real three-dimensional anatomical model, a heat conduction equation and a thermal radiation equation of the human tissue to be subjected to temperature measurement; calculating dielectric constants of the human tissue to be subjected to temperature measurement under different frequencies, and obtaining radiation brightness temperature data of different frequencies under different environmental conditions by combining the temperature distribution data and a real three-dimensional anatomical model of the human tissue to be subjected to temperature measurement; constructing a brightness temperature-temperature conversion matrix by adopting a least square method; and acquiring brightness temperature data of different frequencies of human tissue to be subjected to temperature measurement, substituting the brightness temperature data into the brightness temperature-temperature conversion matrix, and performing inversion to obtain temperatures of different depths of the human tissue to be subjected to temperature measurement. The method is suitable for temperature measurement.

Methods, systems, apparatuses and computer program products are for creating a body heat generation model of a user. A wearable device, such as a ring, is worn by the user. The method includes measuring finger skin temperatures with the wearable device, with at least one temperature sensor, and thereafter with an inverse problem-solving principle, a model is generated. Inner heat flux originating from the user's tissues is one component, and outer heat flux including cooling factors created by ambient temperature around the user and movements made by the user are other components. Thereafter, a thermal cross-sectional 2-dimensional map is constructed, including the finger tissue temperatures using heat convection information of the human tissue, and the result is a body heat generation model of the user. From the obtained model, an indicator of health or wellbeing information of the user may be determined.

Disclosed are a method and device for analyzing human tissue on the basis of a medical image. A tissue analysis device generates training data including a two-dimensional medical image and volume information of tissue by using a three-dimensional medical image, and trains, by using the training data, an artificial intelligence model that obtains a three-dimensional size, volume, or weight of tissue by dividing at least one or more normal or diseased tissues from a two-dimensional medical image in which a plurality of tissues are displayed overlapping on the same plane. In addition, the tissue analysis device obtains a three-dimensional size, volume, or weight of normal or diseased tissue from an X-ray medical image by using the artificial intelligence model.

The invention discloses a human tissue ultrasonic image processing method and device, equipment and a medium, which are applied to the technical field of medical ultrasonic image processing, and comprise the following steps: acquiring a human tissue ultrasonic image under the current treatment depth; performing feature extraction on the human tissue ultrasonic image through a ResNet network to obtain human tissue feature images of different semantic hierarchies, and performing semantic segmentation based on the human tissue feature images of different semantic hierarchies through a UNet network to obtain pixel position information of different human tissues; according to the method, when it is determined that treatment prohibited tissues exist under the current treatment depth based on pixel position information of different human tissues, injury risk prompting is performed based on the treatment prohibited tissues under the current treatment depth, so that different human tissues can be quickly and accurately identified through a ResNet and UNet mixed model, and the treatment prohibited tissues can be quickly and accurately identified through the ResNet and UNet mixed model. Therefore, the interference between the current treatment depth and the treatment-prohibited tissue can be quickly and accurately judged and prompted, and the treatment safety is improved.

An acellular product may be derived from human placenta and may be used in various scenarios for wound healing. Because the product may be acellular, the product may be processed for storage and transportation with minimal degradation. The product may include various scaffolding such as biomaterials or human tissue, and the scaffolding may be infused with various plasmas and agents. The cell-free treatment may maintain the biological activity of many therapeutic agents found within cells and may possess multiple structural components to support cellular attachment. The structural components or scaffolds may function as a reservoir of highly diffusible chemotactic and cellular-programming factors that may be useful to treat injury and disease.

The invention provides a temporomandibular artificial joint replacement device, a preparation method and a surgical robot system.The temporomandibular artificial joint replacement device is characterized in that a mandibular fixing support is fixedly connected with the outer side face of the mandible of the human body, a temporal bone fixing support is fixedly connected with the outer side face of the temporal bone of the human body, a containing cavity is formed in a glenoid fossa liner, and a spherical joint head is movably arranged in the containing cavity; a base layer, a variable-rigidity elastic buffer layer and a surface layer are sequentially arranged on the inner wall of the containing cavity in the thickness direction of the side wall of the glenoid fossa liner. By means of the temporal-mandibular artificial joint replacement device, efficient simulation of the temporal-mandibular joint replacement device on a real human body temporal-mandibular joint structure can be achieved, the structural strength and the use comfort of the temporal-mandibular artificial joint replacement device are improved, and based on artificial intelligence and a surgical robot auxiliary technology, the device is simple in structure and convenient to use. The preparation function of the temporomandibular artificial joint replacement device matched with the human tissue structure and the automatic assembly surgical operation are achieved.

The depth-controllable suturing nail device comprises a handle, a handle cap, an elastic tube, an inhaul cable and a sliding ring, the handle cap is rotatably connected to one end of the handle, a rotation driving assembly is arranged on the handle cap and is in transmission connection with the handle, the rotation driving assembly comprises an indicating block, one end of the elastic tube is connected to the handle, and the other end of the elastic tube is connected to the inhaul cable. The inhaul cable is slidably arranged in the elastic tube in a penetrating mode, one end of the inhaul cable is connected with a suturing nail assembly, the sliding ring is slidably arranged on the handle and is in transmission connection with the other end of the inhaul cable, and when the handle and the sliding ring rotate around the handle cap, the sliding ring can drive the suturing nail assembly to rotate through the inhaul cable. The handle can drive the indicating block of the rotation driving assembly to move in the length direction of the handle. The more the rotation turns of the handle are, the longer the moving distance of the indicating block is, an operator can conveniently master the depth of the suturing nail assembly implanted into the human tissue, and the operator is assisted in accurately and efficiently completing the operation.

The invention relates to a puncture robot breakthrough tissue state identification method based on human body parameter estimation, and the method comprises the following steps: S1, constructing a mathematical model of human body tissues of a far-end patient, and the mathematical model comprises a coupling relation between multiple layers of tissues and dynamic characteristics of the tissues; s2, according to the mathematical model constructed in the step S1, needle point data in the puncture process are collected in real time through a sensor, online parameter identification is conducted on model parameters, and the model parameters are updated in real time to reflect actual changes of tissue in the puncture process; s3, the mutation moment of the parameters in the puncture process is detected according to the model parameters updated in real time in the step S2, and the mutation moment is the moment when the deviation between the model parameters at a certain moment and a historical mean value exceeds a set threshold value, and it is judged that the moment is the moment when the needle tip breaks through the tissue layer. Compared with the prior art, the puncture robot has the advantages that the accuracy and safety of the puncture robot in the operation process are improved, and the like.

The growth factor profile, connective tissue matrix constituents, and immunoprivileged status of urodele extracellular matrix (ECM) and accompanying cutaneous tissue, plus the presence of antimicrobial peptides there, render urodele-derived tissue an ideal source for biological scaffolds for xenotransplantation. In particular, a biological scaffold biomaterial can be obtained by a process that entails (A) obtaining a tissue sample from a urodele, where the tissue comprises ECM, inclusive of the basement membrane, and (B) subjecting the tissue sample to a decellularization process that maintains the structural and functional integrity of the extracellular matrix, by virtue of retaining its fibrous and on-fibrous proteins, glycoaminoglycans (GAGs) and proteoglycans, while removing sufficient cellular components of the sample to reduce or eliminate antigenicity and immunogenicity for xenograft purposes. The resultant urodele-derived biomaterial can be used to enhance restoration of skin homeostasis, to reduce the severity, durations and associated damage caused by post-surgical inflammation, and to promote progression of natural healing and regeneration processes. In addition, the biomaterial promotes the formation of remodeled tissue that is comparable in quality, function, and compliance to undamaged human tissue.

The invention provides a temperature field reconstruction method and device for biological tissue. The method comprises the following steps: constructing a target biological tissue heat transfer finite element model under the influence of a heat source, calculating initial three-dimensional temperature field distribution based on initial parameters, acquiring real-time temperatures of multiple points near the target biological tissue by utilizing a temperature sensor array optical fiber, and performing inversion calculation on tissue heat transfer parameters based on the real-time temperatures to obtain a tissue heat transfer finite element model. And reconstructing three-dimensional temperature field distribution based on the updated heat transfer parameters. The temperature sensor array optical fiber can enter a human body along with the interventional needle and be close to a target tissue in an operation, can be correspondingly bent or twisted along with advancing of the interventional needle, and has good biocompatibility, so that real-time temperatures of multiple points near the target human tissue can be collected in the operation, and the temperature sensor array optical fiber can be used for detecting the temperature of the target human tissue. And accurate real-time three-dimensional temperature field distribution can be obtained based on a finite element model and inversion calculation, so that accurate real-time feedback information can be provided for doctors in an operation, and the safety and effectiveness of the operation are improved.

The utility model belongs to the technical field of medical instruments, and particularly relates to an endoscope and an insertion part thereof. A working channel is arranged in the insertion part, a first suction hole is formed in the peripheral surface of the far end of the insertion part, and the first suction hole penetrates through the side wall of the insertion part and is communicated with the working channel; the peripheral face of the far end of the insertion part protrudes in the radial direction to form a protruding structure, the first suction hole is located in one side of the protruding structure, and the protruding structure exceeds the first suction hole in the radial direction. By means of the protruding structure, the gap can be formed between the first suction hole and the human tissue, the part, provided with the first suction hole, of the insertion part is prevented from being attached to the human tissue, the risk that the first suction hole is blocked by the human tissue is reduced, and the problem that blockage occurs when secretions are sucked out through the insertion part is solved.

The invention discloses a human tissue scaffold spliced by medical modules. The human tissue scaffold is formed by splicing a plurality of medical modules. Compared with the prior art, the method has the advantages that 1, the medical module finished product can better meet the sterile requirement after quality inspection, the medical module finished product is spliced and rapidly implanted into the body on the operation site, the operation time is greatly shortened, the module can be flexibly, rapidly and accurately repaired and manually assembled in the operation according to actual requirements, the operation is simple and convenient, and the clinical popularization value is high; 2, the titanium clip module is accurately configured, the position and the number of titanium clips can be flexibly adjusted according to the specific form of the tissue in the operation and the size of the residual cavity, and accurate positioning of the radiotherapy after the operation is ensured;

Systems and methods are disclosed for receiving a target electronic image corresponding to a target specimen, the target specimen comprising a tissue sample of a patient, applying a machine learning system to the target electronic image to identify a region of interest of the target specimen and determine an expression level of, category of, and / or presence of a biomarker in the region of interest, the biomarker comprising at least one from among an epithelial growth factor receptor (EGFR) biomarker and / or a DNA mismatch repair (MMR) deficiency biomarker, the machine learning system having been generated by processing a plurality of training images to predict whether a region of interest is present in the target electronic image, the training images comprising images of human tissue and / or images that are algorithmically generated, and outputting the determined expression level of, category of, and / or presence of the biomarker in the region of interest.

The invention discloses an umbilical vein catheterization virtual-entity fusion training system based on a novel material, and relates to the technical field of medical simulation training. According to the system, a dynamic three-dimensional umbilical vein anatomical model is constructed through the virtual simulation unit, the entity operation unit adopts a bionic gradient material to simulate neonatal umbilical tissue, and the binding force feedback unit realizes tactile-visual dual-channel interaction. Comprising a multi-source coupling coordinate calibration algorithm, a viscoelastic layered deformation transmission algorithm and the like, and the problems of insufficient operation authenticity and feedback lagging in traditional training are solved by dynamically matching virtual and entity operation spaces and simulating real tissue mechanical response. The novel material preparation unit realizes mechanical property matching with human tissues through a nano-composite process, and the environment simulation unit can reproduce various pathological scenes. The immersion and effectiveness of operation training are remarkably improved, and the method is suitable for standardized training of medical staff in the neonatology department.

The invention discloses an ultrasonic imaging system for accurately acquiring a heart section under any body position. The ultrasonic imaging system comprises a plurality of two-dimensional ultrasonic arrays, a multi-channel ultrasonic signal acquisition module and a three-dimensional ultrasonic imaging module, wherein the spatial positions of the two-dimensional ultrasonic arrays are randomly distributed; the plurality of two-dimensional ultrasonic arrays, the multi-channel ultrasonic signal acquisition module and the three-dimensional ultrasonic imaging module are connected in sequence; wherein the plurality of two-dimensional ultrasonic arrays comprise: a plurality of ultrasonic transducer arrays form regional line scanning or regional surface scanning or cross surface scanning; according to the invention, more detailed images are provided for doctors, so that the lesion can be more accurately positioned and evaluated; the problems that in wearable ultrasonic heart imaging, correct imaging sections are difficult to collect, and the imaging sections change in movement can be solved. The device is not only suitable for heart, but also suitable for brain, liver, kidney, bladder, aorta abdominalis, inferior vena cava and other human tissues and parts.

The invention discloses a noninvasive deep time domain interference electrical stimulation system and method applied to spinal cord rehabilitation, and belongs to the technical field of medical instruments. Difference frequency current is output through the two groups of electrode pairs connected to the electrical stimulator body, so that time domain interference stimulation is generated for the spine, and difference frequency envelope is generated in human tissue. Moreover, the lead wire connected with the electrode is provided with the length scale, so that measurement can be conveniently carried out on the skin on the surface of the spine, and the placement position of the electrode on the surface of the back skin can be quickly determined. The invention further provides an electrical stimulation parameter optimization method, an optimal electrode placement scheme can be quickly generated for a target object, and the difficulty of performing spinal cord rehabilitation by using noninvasive deep time domain interference electrical stimulation clinically is greatly simplified.

The invention discloses a method and device for judging the ablation effect of an ablation system and the ablation system. The ablation system comprises a spherical catheter, a back polar plate and an energy release device. The spherical catheter comprises a catheter body and a spherical head end arranged on the catheter body, and a plurality of electrodes are arranged at the spherical head end. Firstly, a current overall loop impedance value of multiple electrodes from a human body to a back electrode plate is obtained, ablation effective power is calculated according to the current overall loop impedance value, and then the ablation effect is judged according to the ablation effective power. In this way, the effective power acting on the human tissue can be accurately calculated, and therefore the ablation effect can be accurately evaluated.

The invention relates to a physical therapy equipment parameter optimization method based on a terahertz technology, which comprises the following steps of: constructing a frequency stepping and pulse width combination mechanism of terahertz irradiation parameters to adapt to microscopic heterogeneity of water molecule distribution in human tissues, and exciting a tissue area which is originally in a low response state by expanding an absorption window range; setting an irradiation duration and duty ratio strategy, enabling a part of the tissue structure to generate reversible conformational deformation under terahertz micro-thermal stimulation, and regulating and controlling a scattering path and an interference state of local terahertz waves by utilizing the conformational deformation; the method has the beneficial effects that the microcosmic non-uniform tissue area is activated by utilizing the high-selectivity absorption characteristic of terahertz waves on water molecules and biological polar groups and through a combined mechanism of frequency stepping and pulse width, and the coupling efficiency and biological effect strength of energy in target tissue are remarkably improved.

The invention discloses harmless treatment equipment for human tissue waste, and belongs to the technical field of harmless treatment of medical waste. The device comprises an incinerator, wherein the incinerator comprises a furnace body of which the top is provided with an opening; the incineration grinding assembly comprises a lower grinding disc rotationally mounted at the bottom of the furnace body and an upper ceramic grinding disc mounted at the upper part of the furnace body through a plurality of suspension rods; and the heat cycle crushing assembly comprises a conical crushing barrel with a small bottom opening end fixed to the circular truncated cone hole, a crushing motor fixed to the top of the cover body in a sealed mode, a crushing blade fixed to the bottom end of a rotating shaft of the crushing motor, and heat cycle fan blades fixed to the upper portion of the rotating shaft of the crushing motor. According to the equipment, a small amount of human tissue waste can be subjected to local harmless treatment, firstly, the human tissue waste with large particles is crushed through the crushing motor and the crushing blades, then incineration and grinding are conducted through the incineration and grinding assembly, and finally harmless ash residues are formed.

The invention relates to the technical field of biopsy sampling, and discloses a gastroenterology biopsy sampler which comprises a biopsy sampling head and a gastroscope head body located on one side of the biopsy sampling head, a sampling hole is formed in the gastroscope head body, and the biopsy sampling head is slidably connected into the sampling hole. The biopsy sampling head is internally provided with a sampling port, one end of the sampling port is provided with an adsorption hole, the adsorption hole is communicated with the biopsy sampling head, and the other end of the sampling port is slidably connected with an arc-shaped cutter; an elastic assembly is fixed to the inner wall of the biopsy sampling head, the cutting position of an arc-shaped cutter connected to a sampling opening in a sliding mode can be adjusted, human tissue in the sampling opening can be conveniently cut, the purpose that a human tissue incision is smooth in the cutting process can be achieved, the sampling wound surface of the human tissue can be reduced, and the sampling efficiency is improved. A sampling part is not prone to bleeding, wound healing is not affected, and therefore the sampling effect is improved.