The invention provides a percutaneous nephroscope lithotripsy and lithotripsy training model and a preparation method thereof, and relates to the technical field of medical treatment. The percutaneous nephroscope lithotripsy and lithotomy training model comprises a container, an ultrasonic permeable material, simulated fat and a kidney, the container is filled with the ultrasonic permeable material, the kidney is wrapped by the simulated fat, the simulated fat is fixed in the ultrasonic permeable material, the simulated fat comprises chicken fat, leaf fat or animal fat, and the kidney is fixed in the simulated fat. The perirenal fat texture and perirenal substance filling can be fully simulated; and stones are fixed in the kidney calyx of the kidney. The training model is convenient to take materials, fully simulates touch and force feedback of real operation, and can be used for training of kidney ultrasound image recognition, puncture, expansion, lithotripsy and the like, so that medical staff can obtain real skill training touch, and surgical skills are improved; the training model is simple in training environment requirement, saves investment of sites, labor and the like, and realizes daily operation training.