3 results about "Cancer surgery" patented technology

The application belongs to the technical field of biomedical materials, and discloses a acutine-chitosan / calcium carbonate hemostatic sponge as well as a preparation method and application thereof. The acutine and chitosan are condensed to obtain acutine-chitosan, and then the acutine-chitosan is reacted with sodium carbonate, calcium hydroxide and urea to form the acutine-chitosan / calcium carbonate hemostatic sponge. In-vivo and in-vitro experiments verify that the sponge can be used for hemostasis and antibiosis, and due to the pH sensitivity of the acutine-chitosan, the acutine can be intelligently controlled to be released under acidic conditions (cancer acidic environment), so that the sponge can be used for rapid hemostasis during cancer surgery, and also helps to prevent recurrence of liver cancer after surgery. Therefore, the multifunctional acutine-chitosan / calcium carbonate hemostatic sponge of the application provides a 'one-stop' synergistic strategy for intraoperative hemostasis and postoperative prevention of tumor recurrence of liver cancer, and has great clinical application potential.

This invention provides an application of *Lactobacillus paracasei* IOB413 metabiotic and its composition in gastric cancer, belonging to the field of microbial technology. *Lactobacillus paracasei* IOB413 has the preservation number CGMCC No. 16022. Its metabiotic can inhibit gastric cancer progression by suppressing epithelial-mesenchymal transition in tumor cells and regulating the IL-6 / JAK2 / STAT3 signaling pathway. The composition with folic acid has a synergistic effect, more effectively reducing tumor volume and lowering the levels of pro-inflammatory factors and tumor markers. It has high safety and is suitable as an adjuvant therapy before and after gastric cancer surgery, providing a new approach to gastric cancer treatment.

This invention relates to the field of postoperative assessment technology, and more particularly to a quantitative assessment method, system, and storage medium for emergency colon cancer surgery. It includes: collecting postoperative recovery data from patients, including preliminary indicators such as the time point of bowel function recovery, the range of bowel movement frequency fluctuations, and the intensity of overall physical activity; combining time series analysis and activity intensity information to identify potential high-risk time points; based on the comparison results of the high-risk time point set with preset thresholds, data fusion analysis of the interaction of preliminary indicators to construct a comprehensive recovery trend vector, and determining recovery pattern classification through pattern matching; based on the recovery pattern classification, constructing a dynamic adjustment matrix, adjusting the weights of each indicator, and calculating the overall recovery score through weighted average; and generating a personalized intervention adjustment sequence based on the relationship between the overall recovery score and the preset threshold. This invention solves the problems of strong subjectivity and poor real-time performance in postoperative recovery assessment, and achieves accurate and personalized recovery assessment and intervention adjustment.