8 results about "Cancer surgery" patented technology

The application belongs to the technical field of biomedical materials, and discloses a acutine-chitosan / calcium carbonate hemostatic sponge as well as a preparation method and application thereof. The acutine and chitosan are condensed to obtain acutine-chitosan, and then the acutine-chitosan is reacted with sodium carbonate, calcium hydroxide and urea to form the acutine-chitosan / calcium carbonate hemostatic sponge. In-vivo and in-vitro experiments verify that the sponge can be used for hemostasis and antibiosis, and due to the pH sensitivity of the acutine-chitosan, the acutine can be intelligently controlled to be released under acidic conditions (cancer acidic environment), so that the sponge can be used for rapid hemostasis during cancer surgery, and also helps to prevent recurrence of liver cancer after surgery. Therefore, the multifunctional acutine-chitosan / calcium carbonate hemostatic sponge of the application provides a 'one-stop' synergistic strategy for intraoperative hemostasis and postoperative prevention of tumor recurrence of liver cancer, and has great clinical application potential.

This invention provides an application of *Lactobacillus paracasei* IOB413 metabiotic and its composition in gastric cancer, belonging to the field of microbial technology. *Lactobacillus paracasei* IOB413 has the preservation number CGMCC No. 16022. Its metabiotic can inhibit gastric cancer progression by suppressing epithelial-mesenchymal transition in tumor cells and regulating the IL-6 / JAK2 / STAT3 signaling pathway. The composition with folic acid has a synergistic effect, more effectively reducing tumor volume and lowering the levels of pro-inflammatory factors and tumor markers. It has high safety and is suitable as an adjuvant therapy before and after gastric cancer surgery, providing a new approach to gastric cancer treatment.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for replenishing qi, enriching blood, tonifying spleen and nourishing kidney as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 2 to 12 parts of radix angelicae sinensis, 5 to 20 parts of radix codonopsis, 5 to 20 parts of radix astragali seu hedysari, 2 to 12 parts of rhizoma atractylodis macrocephalae, 2 to 15 parts of poria cocos, 3 to 13 parts of colla corii asini, 3 to 13 parts of tortoise-shell glue, 2 to 12 parts of herba cistanche, 5 to 15 parts of radix rehmanniae praeparata, 3 to 15 parts of rhizoma polygonati, 3 to 13 parts of herba epimedii, 2 to 12 parts of fructus crataegi, 5 to 15 parts of arillus longan, 2 to 12 parts of fructus ligustri lucidi, 2 to 6 parts of fructus schisandrae chinensis and 1 to 5 parts of cortex cinnamomi. The traditional Chinese medicine composition has the main effects of replenishing qi, enriching blood, tonifying spleen and nourishing kidney, is used for rehabilitation after cancer surgery or chemotherapy and used for resisting cancer relapse, is particularly used for patients with spleen and kidney deficiency type cachexia after cancer surgery or chemotherapy, and improves the problems of emaciation, insomnia, inappetence, mental fatigue and tiredness and the like of the patients with the patients with the spleen and kidney deficiency type cachexia after cancer surgery or chemotherapy.

The invention discloses a target detection method in a robot-assisted laparoscopic colon cancer surgery, relates to the technical field of target detection, and aims at improving a YOLOv13 model in an application scene of the robot-assisted laparoscopic colon cancer surgery. The distinguishing capability of the model on fine-grained features such as lymph node edges and tumor textures is enhanced, and the problem of confusion of tiny targets and backgrounds is solved; average pooling preprocessing and double-branch differentiation downsampling are adopted, small target details and large target high response areas are reserved at the same time in the downsampling process, high-quality feature input is provided for subsequent BiFPN, and the problem of small target feature loss is solved; through bidirectional feature interaction, CARAFE up-sampling and P3-B3 same-layer jump connection, the weight of low-resolution low-layer features is enhanced, the problem of multi-scale target detection imbalance is solved, and especially the detection precision of tiny lymph nodes is improved.

The present application is suitable for the technical field of plant extraction and separation, and provides a polysaccharide compound with clear molecular structure, which is suitable for treating patients with advanced cancer (surgical conditions have been lost, survival time is only three to six months, and chemotherapy conditions are still available), comprising: S1, drying and crushing Ganoderma lucidum; S2, mixing with water in a sealed container to extract effective components under high temperature and high pressure; S3, removing residues from the concentrated liquid with effective components; and S4, preparing the residue-removed concentrated liquid into a certain concentration to obtain polysaccharide with effective components through column chromatography. The polysaccharide with effective components has good water-soluble performance, is easy to be absorbed by the human body, has antitumor efficacy, and has efficacy in preventing the occurrence of tumors in humans, especially when used in combination with chemotherapy drugs, the toxic and side effects of the chemotherapy drugs on the human body can be eliminated, and the control, reduction, and elimination of tumor cells are all supported by corresponding experimental data.

This invention relates to the field of postoperative assessment technology, and more particularly to a quantitative assessment method, system, and storage medium for emergency colon cancer surgery. It includes: collecting postoperative recovery data from patients, including preliminary indicators such as the time point of bowel function recovery, the range of bowel movement frequency fluctuations, and the intensity of overall physical activity; combining time series analysis and activity intensity information to identify potential high-risk time points; based on the comparison results of the high-risk time point set with preset thresholds, data fusion analysis of the interaction of preliminary indicators to construct a comprehensive recovery trend vector, and determining recovery pattern classification through pattern matching; based on the recovery pattern classification, constructing a dynamic adjustment matrix, adjusting the weights of each indicator, and calculating the overall recovery score through weighted average; and generating a personalized intervention adjustment sequence based on the relationship between the overall recovery score and the preset threshold. This invention solves the problems of strong subjectivity and poor real-time performance in postoperative recovery assessment, and achieves accurate and personalized recovery assessment and intervention adjustment.

The subject matter of the present invention is novel fluorescent compounds useful for marking tumor tissue, methods for their preparation, and their use as monitoring or diagnostic tools or tools for assisting cancer surgery.

Disclosed herein a method of visualizing and treating a cancer in a subject in need thereof, the method comprising: administering to the subject a tumor homing agent and a nerve homing agent. The technology described herein provides direct visualization of tissue, cells, and margins and direct visualization of nerves simultaneously in surgical settings and pathology samples in order to improve surgical outcomes in cancer surgeries and reduce comorbidities for patients.