1583 results about "Chinese herbs" patented technology

The invention belongs to the technical field of medicinal and edible Chinese herbal medicine alcoholic drink, and particularly relates to lactobacillus plantarum and application thereof in fermentation of ginsenoside. The lactobacillus plantarum is specifically lactobacillus plantarum L100, and the preservation number of the lactobacillus plantarum L100 is CGMCC (China General Microbiological Culture Collection Center) No. 34425. The lactobacillus plantarum L100 has the function of converting and preparing the rare ginsenoside, basic components of ginseng can be directionally converted into high-value rare ginsenoside (such as Rg3, Rg5 and Rh1), and particularly, the lactobacillus plantarum L100 has extremely high specificity on generation of F5 and Rh10. Ginseng fermentation liquor obtained by fermenting ginseng through lactobacillus plantarum L100 and extracting solutions of medicinal and edible components such as codonopsis pilosula, astragalus membranaceus, liquorice and cistanche deserticola are used for preparing the liqueur, and a liqueur product with potential effects in the aspects of oxidation resistance, inflammation resistance, immunoregulation and the like is obtained.

The invention discloses a Chinese herbal medicine intelligent drip irrigation regulation and control system based on end-cloud cooperation, and relates to the technical field of agricultural intelligent irrigation, and the system comprises an edge equipment end which is deployed in a Chinese herbal medicine planting area, comprises a multi-mode sensor module, a communication module and an irrigation execution mechanism, and is used for collecting soil humidity, illumination intensity and meteorological data in real time, and sending the collected data to a cloud server; and the drip irrigation valve is controlled through the irrigation executing mechanism. According to the Chinese herbal medicine intelligent drip irrigation regulation and control system based on end-cloud collaboration, through an end-cloud collaboration architecture and a hierarchical decision-making mechanism, the drip irrigation regulation and control accuracy and real-time performance in a Chinese herbal medicine planting environment are improved. A local AI inference engine of the edge equipment end is combined with a dynamic learning module, an optimization instruction can be automatically generated during network fluctuation, dependence on real-time communication of the cloud end is reduced, and continuity and reliability of irrigation operation in complex terrains are ensured.

The invention discloses a traditional Chinese medicine prescription evaluation system and method based on artificial intelligence, and belongs to the technical field of traditional Chinese medicine prescription evaluation. The data preprocessing module is used for preprocessing the data related to the Chinese herbal medicines to obtain preprocessed data; the feature extraction module is used for extracting key features of the preprocessed data to obtain a key feature data set; the model training module is used for constructing a neural network model, training the neural network model through the key feature data set, and generating an evaluation model; the evaluation module is used for acquiring the traditional Chinese medicine formula in real time and inputting the traditional Chinese medicine formula into an evaluation model to generate an evaluation result; and the result output module is used for visually displaying the evaluation result and generating a prescription optimization suggestion. Through the method, rapid, accurate and objective evaluation of the traditional Chinese medicine formula can be realized, and technical support is provided for modernization and internationalization of traditional Chinese medicines.

The invention provides a Chinese herbal medicine indication discovery method and system based on hypergraph convolution. The method is mainly based on two hypergraph convolutions, and makes full use of biological knowledge features of effective components and target spots, high-dimensional Chinese herbal medicine-effective component association and target spot-indication association including molecular fingerprints of the effective components, sequence information of the target spots and high-order features in hypergraphs. The method is low in model complexity and low in power consumption; the association relationship between the Chinese herbal medicine and the indications in the network can be accurately predicted, and reliable technical support is provided for finding the indications of the Chinese herbal medicine.

The invention provides a Chinese herbal medicine raw material industrial extraction process temperature monitoring system, and relates to the technical field of traditional Chinese medicine industrial extraction, and the system comprises a multi-dimensional sensing module, an intelligent control module, a self-adaptive execution module, a data co-processing module and an anti-interference module. The multi-dimensional sensing module synchronously collects temperature field distribution and extracts environment and effective component feedback parameters; a dynamic temperature control model based on a heat sensitivity feature library and a process knowledge library is built in the intelligent control module, and multi-source data is coupled and analyzed to generate an adaptive regulation and control instruction; the self-adaptive execution module regulates the heat transfer medium, the heating unit and the cooling unit in a closed-loop linkage manner; the data co-processing module is used for realizing data storage, correlation analysis and full-link tracing; and the anti-interference module suppresses data noise. The system solves the problems that an existing system is single in monitoring dimension, poor in adaptability and weak in interference resistance, temperature control precision and product batch consistency are improved, it is guaranteed that the extraction process is stable, and reliable support is provided for industrial extraction of Chinese herbal medicine materials.

The invention relates to an exosome composition for improving sleep quality. The exosome composition comprises a lavender exosome, a chamomile exosome and a saffron crocus exosome. The exosome composition disclosed by the invention can be used for improving the expression level of GABA (gamma-aminobutyric acid) related proteins of neuronal cells, promoting the expression of brain-derived neurotrophic factors (BDNF) of the neuronal cells, promoting the synaptic growth of the neuronal cells, improving the CL <-> level of the neuronal cells and inhibiting the inflammatory factor level of microglial cells. The exosome composition disclosed by the invention can be used for improving sleep quality reduction caused by various body discomfort, and has a more obvious using effect than that of the same Chinese herbal medicine extract.

The invention relates to the technical field of Chinese herbal medicine cultivation, in particular to a Chinese herbal medicine cultivation system which comprises an environment monitoring and regulation module, a health monitoring and early warning module, an intelligent scheduling and response module and a data analysis module. The environment monitoring and regulation module monitors environment parameters in a cultivation environment in real time; the health monitoring and early warning module monitors health conditions of Chinese herbal medicines in real time and analyzes diseases and insect pests or nutrition problems; the intelligent scheduling and response module optimizes resources of a cultivation environment; the data analysis module analyzes the growth trend and environmental adaptability of the Chinese herbal medicines based on the optimized growth conditions and cultivation environment resources of the Chinese herbal medicines, and generates cultivation suggestions; according to the method, corresponding measures can be identified and taken as early as possible, so that the outbreak of plant diseases and insect pests is avoided or reduced, and the growth quality and yield of plants are optimized.

The preparation method comprises the following steps: (1) mixing Chinese herbal medicine powder and a waterproof agent according to a ratio, sieving and uniformly stirring; (2) adding a proper amount of sticky powder and water, mashing into a ball, repeatedly beating and kneading into uniform mud, wrapping with a preservative film, and putting in a shade place for fermenting the mud; (3) kneading the fermented fragrant mud to be round, buckling the fragrant mud into the fragrant bead mold coated with the release agent, compacting, drawing the mold, and scraping off redundant parts; 4) placing the demolded aromatic beads in a dark, dry and ventilated place for drying in the shade, and repeatedly turning over; (5) hollowing out along the axis, and grinding and polishing to prepare the mixed aromatic beads; and 6) baking the polished mixed aromatic beads to prepare the waterproof Chinese herbal medicine mixed aromatic beads. The waterproof agent is added into the synthetic aromatic beads, then the waterproof agent is transferred to the surface through baking, and meanwhile, the interface interaction between the waterproof agent and the synthetic aromatic beads is enhanced, so that the synthetic aromatic beads are tightly wrapped by the waterproof agent, and the waterproof and lasting waterproof effects are achieved.

The invention relates to the technical field of Chinese herbal medicine fermentation, and discloses a mixed strain fermentation method for efficient conversion of non-medicinal parts of traditional Chinese medicine, which comprises the following steps: constructing an intelligent fermentation system comprising a plurality of independent fermentation units, respectively culturing different strains such as aspergillus niger, bacillus subtilis, saccharomyces cerevisiae and the like in each fermentation unit, the online sensor is integrated in the system and used for monitoring key fermentation parameters in real time, and a fermentation model and an optimization algorithm are arranged in the system and can automatically adjust fermentation conditions. An intelligent fermentation system comprising a plurality of independent fermentation units is constructed, precise classification pretreatment and mixing according to a specific ratio are carried out on rhizoma polygonati stems and leaves and gentian stems and leaves, and an intelligent control system is utilized to dynamically regulate and control the fermentation process, so that the synergistic effect of different strains such as aspergillus niger, bacillus subtilis and saccharomyces cerevisiae is fully exerted, and the fermentation efficiency is improved. The dissolution rate and the conversion rate of active ingredients in the non-medicinal part of the traditional Chinese medicine are improved.

The invention relates to the technical field of target detection, and discloses a Chinese herbal medicine and foreign matter detection method and system, a storage medium and a product. Based on a Chinese herbal medicine and foreign matter detection model, whether foreign matter exists in the to-be-detected image or not is judged according to the to-be-detected image, and the Chinese herbal medicine and foreign matter detection model is an improved YOLOv8 model. According to the Chinese herbal medicine and foreign matter detection method provided by the invention, the adopted model is an improved YOLOv8 model, and the feature extraction capability, the detection precision and the detection speed of the model are improved while the light weight of the model is realized.

The invention discloses a Chinese herbal medicine knowledge graph construction method and system, and the method comprises the steps: collecting structured data and unstructured data, and generating a drug property and pharmacology data table; extracting property and flavor channel tropism attributes of the medicinal materials, generating a medicinal property triple and a pharmacological triple, and establishing preliminary cross-domain association; defining logical constraints and compatibility rules of nature and flavor channel tropism, and constructing a causal reasoning chain; performing spatial semantic mapping on the channel tropism attributes and the pharmacological entities to generate a dynamic cross-layer mapping relationship; using an attribute graph database to store node types and edge types, and constructing a hybrid index; new data streams are collected in real time, the atlas is updated, and an intelligent decision-making interface and a visual interaction platform are provided. Through multi-source fusion, dynamic association, efficient storage and closed-loop optimization, the problems of semantic segmentation, update lag and low retrieval efficiency in traditional Chinese medicine digitization are solved, and scientific and real-time technical support is provided for traditional Chinese medicine modernization research, accurate medication and new medicine research and development.

The present invention belongs to the field of agricultural technology, and in particular to a method for converting Chinese medicine residues into Chinese herbal medicine organic fertilizer using a cobalt-iron catalyst. The method comprises the following steps: (1) synthesizing a cobalt-iron catalyst; (2) mixing and pyrolyzing the Chinese medicine residues and the cobalt-iron catalyst; (3) activating the pyrolysis product to obtain the Chinese herbal medicine organic fertilizer. The process of the present invention is simple and easy to operate, and the prepared cobalt-iron catalyst has excellent catalytic performance and good cyclic stability, and can efficiently and quickly convert the Chinese medicine residues into Chinese herbal medicine organic fertilizer. At the same time, the prepared Chinese herbal medicine organic fertilizer has good water solubility, is rich in abundant plant growth nutrients, and has the effect of increasing production and increasing efficiency of Chinese herbal medicine.

The present invention relates to the technical field of agricultural fertilizers, and discloses a biofertilizer synthesized from Chinese herbal medicines, a preparation method and an application thereof, wherein the biofertilizer is prepared by combining herbal extracts such as astragalus, dandelion, forsythia, gallnut, and liquorice with Chinese herbal medicine residues such as honeysuckle residue, tobacco residue, malt residue, yeast residue, sophora flavescens residue, coptis chinensis residue, and stemonae residue, and is combined with organic fertilizers and nitrogen, phosphorus, and potassium fertilizers, and is fermented by composite microorganisms. The obtained biofertilizer is not only comprehensive in nutrients and easy to absorb, but also rich in natural antibacterial, anthelmintic substances and active microorganisms, which helps to promote crop growth and enhance disease and insect resistance. At the same time, long-term use can improve soil structure, enhance soil fertility and microecological balance, and reduce the use of chemical fertilizers and pesticides, thereby achieving the effects of increased production and efficiency, green environmental protection, and sustainable development.

The invention relates to the technical field of toothpaste preparation, in particular to hydrolyzed procyanidine-containing Chinese herbal medicine nursing toothpaste as well as a preparation method and application thereof.The preparation method of the hydrolyzed procyanidine-containing Chinese herbal medicine nursing toothpaste comprises the following preparation steps: adding a humectant, a thickening agent, a surfactant, a sweetening agent and a preservative into deionized water, and uniformly stirring; uniformly stirring to obtain a mixed solution; adding the abrasive into the mixed solution, and uniformly stirring to obtain paste; and adding the active microcapsules into the paste, uniformly stirring, carrying out vacuum degassing, and filling to obtain the Chinese herbal medicine nursing toothpaste containing hydrolyzed procyanidine. The Chinese herbal medicine care toothpaste is fused with hydrolyzed procyanidine, and shows excellent oral care performance. The oral care solution has obvious inhibition capability on a plurality of common oral pathogenic bacteria, has extremely high bacteriostasis rate, and can effectively block bacterial breeding and maintain oral health from the source. Meanwhile, the toothpaste is excellent in deodorization effect and capable of rapidly decomposing oral cavity peculiar smell molecules and remarkably improving oral cavity freshness.

The invention relates to the field of pharmacy, and discloses a Chinese herbal medicine and marine extract combined antibacterial and anti-inflammatory pharmaceutical composition which comprises the following components in parts by weight: 5-10 parts of baicalin extract; 3 to 7 parts of an andrographolide extract; 2-5 parts of sulfated brown algae polysaccharide; 0.2 to 1 part of sponge extract; wherein the baicalin extract is derived from roots of scutellaria baicalensis and is obtained by extracting with an ethanol-water mixed solvent; the andrographolide extract is derived from the whole herb of andrographis paniculata and is obtained by extracting with an ethanol-water mixed solvent; the sulfated fucoidan is derived from fucoidan and is prepared by enzymolysis and alcohol precipitation methods; the sponge extract is derived from sponge and is obtained by organic solvent extraction, separation and purification. By adopting the technical scheme of synergistically compounding the Chinese herbal medicine active ingredients and the marine extract, the technical effects of destroying a biological membrane barrier and removing stubborn infection lesions in treatment of bacterial vaginitis, candida vaginitis associated biological membrane infection and cervicitis are achieved.

The invention discloses application of rehmannia extracellular vesicles in preparation of a medicine for improving breast cancer bone metastasis bone injury, and belongs to the technical field of biological medicine. The preparation method comprises the following steps: cleaning the root tuber of a fresh rehmannia plant, adding a PBS (Phosphate Buffer Solution), crushing, and filtering by gauze to remove large-particle impurities; performing high-speed centrifugation on the filtrate to remove insoluble residues, then performing ultra-high-speed centrifugation to collect precipitates, re-suspending the precipitates, purifying the precipitates by adopting PEG (Polyethylene Glycol), and centrifugally collecting the precipitates, thereby obtaining the rehmannia extracellular vesicles. The rehmannia extracellular vesicles can effectively target bones, promote proliferation of bone-related cells and remarkably reduce bone injury caused by bone metastasis of breast cancer; bone protection treatment is carried out on breast cancer bone metastasis through the Chinese herbal medicine vesicles sourced from rehmannia, a safe and effective treatment scheme is provided for improving the pathological osteolysis problem caused by breast cancer bone metastasis, a new thought and technical support are provided for prevention and treatment of tumor bone metastasis related diseases, and good clinical transformation prospects are achieved.

The invention belongs to the technical field of biological bacterial fertilizers, and discloses a Chinese herbal medicine carrier-based multifunctional microbial bacterial fertilizer, which comprises a microbial strain group, a Chinese herbal medicine active component group, an organic matter and nutrition carrier, mineral elements and auxiliary components, and a functional synergist. Through the synergistic interaction of Chinese herbal medicine active ingredients and functional microbial flora, breeding of harmful bacteria in soil is inhibited, synthesis of acetylcholin esterase of nematodes is interfered, a continuous cropping disease occurrence chain is blocked from the source, and meanwhile, organic acid and flavonoid substances slowly released by a Chinese herbal medicine carrier are utilized to activate resistance gene expression of a plant system, so that the disease resistance of the nematodes is improved. The tolerance threshold of crops to high temperature, cold damage and diseases is enhanced; in the composite carrier, humic acid and diatomite are crosslinked through hydrogen bonds to form a stable granular structure, the cation exchange capacity and porosity of soil are effectively improved, the strong hydration capacity of polyglutamic acid is combined to lock nutrients and moisture, and development of meristem of a root system and proliferation of capillary roots are promoted.

The invention relates to the technical field of microbial fermentation, and discloses a metabolite fingerprint spectrum construction method of a probiotic fermentation type Chinese herbal medicine preparation. The method is realized by sequentially executing a metabolite data acquisition process, a chromatographic data preprocessing process, a metabolite fingerprint spectrum modeling process, a spectrum construction optimization process and a metabolite fingerprint spectrum generation process. In the metabolite data acquisition process, original metabolite data of the probiotic fermented Chinese herbal medicine preparation is acquired; in the chromatographic data preprocessing process, original metabolite data is subjected to signal processing and feature extraction, and preprocessed chromatographic data is obtained; in the metabolite fingerprint modeling process, a preliminary fingerprint is constructed based on the preprocessed chromatographic data; in the atlas construction optimization process, parameter optimization and accuracy improvement are carried out on the initial fingerprint atlas, and the optimized fingerprint atlas is obtained; in the metabolite fingerprint spectrum generation process, the optimized fingerprint spectrum is integrated, and a final metabolite fingerprint spectrum is generated.

The invention relates to the technical field of seedling planting machines, and provides a Chinese herbal medicine seedling planting machine which comprises a moving frame, a handle is fixedly connected to one side of the top end of the moving frame, and moving wheels are arranged at the bottom end of the moving frame; a motor is started to drive a belt to rotate, the belt drives a second rotating wheel to rotate, the second rotating wheel drives a rotating rod to rotate, the rotating rod drives a rotating belt to rotate, the rotating belt drives a rake rod to climb on soil, and the soil is loosened, so that a conical soil inserting head can be more easily inserted into the soil; the harrow rod can stir hard objects such as branches or stones on soil, then the hard objects are shoveled up through the harrow rod, then the harrow rod is driven to convey upwards through rotation of the rotating belt, and when the harrow rod is located at the top end of the rotating belt, the hard objects in the harrow rod slide into the collecting box to be collected through inertia of the hard objects. Therefore, the conical soil inserting head can be prevented from being contacted with a hard object when being inserted into the soil to damage the port of the conical soil inserting head so as to influence planting.

The invention discloses a traditional Chinese medicine composition for resisting giant frog blue eye disease pathogen Elizabeth mileli and application of the traditional Chinese medicine composition, and relates to the technical field of aquaculture disease prevention and treatment. It is found for the first time that the radix scutellariae has a good effect of inhibiting the Elizabeth mille, and the herba houttuyniae does not have the effect of inhibiting the Elizabeth mille but can enhance the inhibiting effect of the radix scutellariae on the Elizabeth mille, that is, the herba houttuyniae has a synergistic enhancement effect; the traditional Chinese medicine composition of the radix scutellariae and the herba houttuyniae is expected to be applied to treatment of the blue eye disease of the giant spiny frog, and the Chinese herbal medicine composition is used for replacing antibiotics in the breeding process.

The invention relates to the field of insomnia treatment, in particular to a traditional Chinese medicine composition for treating insomnia caused by upper heat, lower cold and middle-jiao deficiency, which comprises the following Chinese herbal medicines: smoked plum, processed monkshood, cassia twig, ginseng, angelica sinensis, asarum, rhizoma zingiberis, pericarpium zanthoxyli, golden cypress, coptis chinensis, bitter wine, polished round-grained rice, honey, lily, tuber fleeceflower stem, hericium erinaceus, polygala tenuifolia and poria with hostwood. The pill is prepared from a traditional Chinese medicine composition of dark plum, processed monkshood, cassia twig, ginseng, angelica sinensis, asarum, rhizoma zingiberis, pericarpium zanthoxyli, golden cypress, coptis chinensis, bitter wine, polished round-grained rice, honey, lily, tuber fleeceflower stem, hericium erinaceus, polygala tenuifolia and poria with hostwood. The traditional Chinese medicine composition can comprehensively improve insomnia symptoms caused by upper heat, lower cold and middle-jiao deficiency, and is quick in effect taking, high in safety and small in side effect.

The present invention discloses an intelligent automatic medicine dispensing device, which belongs to the technical field of medical equipment, and comprises a horizontal moving module, a vertical moving module is installed on the horizontal moving module, a moving seat is installed on the moving screw rod of the vertical moving module, a plurality of storage boxes are installed on the outside of the vertical plate, the docking box is installed on the outside of the moving seat through a pneumatic driving structure, a collecting box is connected to the bottom of the docking box, and during the transportation process, it only needs to continuously transport gas to the inside of the docking pushing capsule through a secondary through pipe, and the gas will push the storage baffle to tilt when entering the inside of the docking pushing capsule, and the storage baffle will make the Chinese herbal medicine located in the storage box quickly fall into the collecting box for collection when it is tilted, and there is no need to repeat the medicine taking process for multiple times, and the pneumatic simple collecting mechanical arm is driven by gas as a whole, with a small load, and is easy to maintain and use.

The invention discloses a Qingyuan chicken feed production process, which comprises: 1, raw material preparation: selecting the following raw materials by weight: 40-50 parts of corn, 20-30 parts of soybean meal, 10-15 parts of wheat bran, 5-10 parts of fish meal, 3-5 parts of bone meal, 2-4 parts of shell powder, 3-6 parts of a Chinese herbal medicine additive, 0.5-1 part of composite vitamins, and 0.5-1 part of composite minerals, wherein the Chinese herbal medicine additive is prepared from radix astragali, radix codonopsis, poria cocos, rhizoma atractylodis macrocephalae, fructus crataegi, fructus hordei germinatus and medicated leaven; 2, pretreating the raw materials, respectively screening and removing impurities from the corn, the soybean meal and the wheat bran, and crushing the fish meal, the bone meal and the shell powder; by reasonably matching various raw materials and particularly adding the specially prepared Chinese herbal medicine additive, the immunity of the Qingyuan chickens can be improved, diseases can be reduced, and the use amount of medicines in the breeding process can be reduced.

The invention discloses a method for extracting active ingredients of traditional Chinese medicinal materials based on ultralow-temperature crushing and deep eutectic solvent synergy, a tableted candy for dispelling effects of alcohol and protecting liver and a preparation method of the tableted candy. The ultralow-temperature crushing and deep eutectic solvent synergy extraction technology is combined, and the active ingredients of the traditional Chinese medicinal materials with homology of medicine and food are extracted at low temperature; the method comprises the following steps: firstly, quickly freezing a raw material by using liquid nitrogen and mechanically crushing the raw material to improve the cell wall breaking rate, then stirring and mixing a deep eutectic solvent based on choline chloride and glycerol with water to reduce the viscosity of the solvent for extraction, and carrying out ultrasonic extraction, filtration, macroporous adsorption resin recovery and other steps to obtain a high-purity extract. According to the preparation method, the extraction rate of active substances in the traditional Chinese medicinal materials is increased, and extracts of multiple medicinal and edible Chinese herbal medicines such as lucid ganoderma, radix puerariae, hawthorn and olive are compounded into the tablet candy, so that liver injury caused by alcohol is effectively improved, and side effects caused by long-term administration of medicines can be effectively avoided.

The invention belongs to the field of shampoo, and discloses hair-blacking and alopecia-stopping Chinese herbal medicine shampoo and a preparation process thereof. The shampoo cream is prepared from the following raw materials in parts by weight: 10 parts of cacumen biotae, 10 parts of Chinese honey locust, 110 parts of soapberry, 6 parts of szechwan chinaberry fruit, 5 parts of lucid ganoderma, 5 parts of pine needle, 5 parts of eclipta, 5 parts of garden balsam stem, 5 parts of tea seed powder, 5 parts of rhizoma drynariae, 5 parts of glossy privet fruit, 5 parts of mulberry leaf, 4 parts of duckweed, 3 parts of polygonum multiflorum, 3 parts of angelica sinensis, 3 parts of tribulus terrestris and 2 parts of ginseng. The hair-loss-preventing and hair-growing shampoo has the comprehensive effects of preventing hair loss and growing hair, namely activating hair follicle activity, promoting hair cell proliferation and improving scalp microcirculation through the components such as the radix polygoni multiflori preparata and the cacumen biotae. The hair blackening and brightening agent contains eclipta, mulberry leaves and the like, can promote melanin synthesis, inhibit decomposition, repair damaged hair and enhance hair gloss. The effects of controlling oil, removing dandruff, relieving itching, resisting inflammation, nourishing and conditioning are achieved.

The invention provides a desert sand land liquorice planting method, and belongs to the technical field of Chinese herbal medicine planting. The desert sand land licorice planting method comprises the following steps that wheat crops are sown from April to May, a regulating agent is sprayed when the plant height of the wheat crops is 14-18 cm so that the wheat crops can not grow any more, and licorice is sown between rows of the wheat crops. The wheat crops are planted in advance, growth of the wheat crops is inhibited at the proper plant height, a wind-shield wall can be formed, the field evaporation capacity can be reduced through proper shielding, the survival rate of the direct-seeding liquorice in the desert sand land is increased, and follow-up growth of the liquorice is not affected.

The invention relates to an extracellular vesicle composition for aiding sleep as well as a preparation method and application thereof. The composition comprises two or more of passion flower extracellular vesicles, chamomile extracellular vesicles and liquorice extracellular vesicles. According to the extracellular vesicle composition, a combined formula is adopted, and the CL-level of cells is improved, the expression level of GABA related proteins is improved, the expression of brain-derived neurotrophic factors (BDNF) of the cells is promoted, and the synaptic growth of neuronal cells is promoted in a multi-dimensional combined mode that the passiflora edulis is compounded with multiple Chinese herbal medicine extracellular vesicles; the sleep-aiding pillow has the advantages that multi-aspect efficient sleep-aiding effects can be realized, sleep time can be shortened, and sleep quality can be improved. Meanwhile, the extracellular vesicle composition disclosed by the invention adopts nano-scale raw materials, has good permeability, and is more easily absorbed and ingested by cells and skin to play a role.

The invention is applicable to the technical field of toothpaste preparation, and particularly relates to mild stain-removing and whitening toothpaste containing diatomite and coconut shell carbon and a preparation method of the mild stain-removing and whitening toothpaste. The mild stain-removing and whitening toothpaste comprises 9-30% of Changbai Mountain diatomite abrasive, 32-38% of sorbitol, 2-4% of sodium lauroyl silicate, 2-3% of polyethylene glycol 400 and 0.5-2% of coconut shell carbon. The toothpaste is prepared from the following components in percentage by weight: 0.6 to 1 percent of polyvinylpyrrolidone, 0.5 to 0.8 percent of honeysuckle flower extract, 0.5 to 0.7 percent of pseudo-ginseng extract, 0.5 to 0.8 percent of xanthan gum, 0.1 to 0.2 percent of 1, 2-hexanediol, 0.5 to 0.8 percent of essence and water. The diatomite and coconut shell carbon used in the invention are refined natural food-grade raw materials, do not contain chemical components, have low hardness, are suitable for children and sensitive people, and do not damage enamel; the selected Changbai Mountain diatomite and coconut shell carbon with the iodine value of 1500-3000 have a synergistic effect, and the Chinese herbal medicine extract is added to assist in degerming; the adsorption, whitening and deodorizing capabilities of the toothpaste are greatly improved, and the toothpaste can quickly remove stains, whiten and remove bad breath.

The invention discloses a holothurian culture feed additive and a preparation method thereof, and belongs to the technical field of aquaculture. According to the technical scheme, the holothurian culture feed additive comprises the following components in percentage by mass: 45%-55% of fish meal, 2%-3% of butyric acid bacteria, 25%-30% of compound probiotics, 2%-4% of a Chinese herbal medicine extract, 8%-12% of a fermentation substrate, 10%-15% of seaweed meal, 0.5%-1% of vitamin E, 0.5%-1% of selenium yeast and the balance of a carrier, the compound probiotics are composed of lactic acid bacteria, bacillus and photosynthetic bacteria according to the mass ratio of 2: 1: 1; the Chinese herbal medicine extract is a mixture of astragalus polysaccharide and an asarum extract in a mass ratio of 3: 1; through the synergistic effect of the fish meal, the compound probiotics, the Chinese herbal medicine extract and other components, nutrition balance and intestinal flora regulation and control are achieved, the problems of slow growth, intestinal diseases and water quality pollution caused by traditional feed are effectively solved, and the sea cucumber feed has the advantages that the survival rate of sea cucumbers is increased, and the culture benefits are increased.

The invention discloses a fermented Chinese herbal medicine preparation for improving eggshell quality and a preparation method of the fermented Chinese herbal medicine preparation, Chinese herbal medicines mainly comprise motherwort, folium artemisiae argyi, radix isatidis and jujube powder, and fermentation probiotics mainly comprise bacillus subtilis, bacillus coagulans, enterococcus faecalis, lactobacillus plantarum and saccharomycetes. The fermented traditional Chinese medicine preparation produced by the invention has the effects of improving intestinal health and immunity and improving oxidation resistance and stress resistance of laying hens in laying hen production, so that the egg quality and eggshell quality of the laying hens are improved.