51 results about "Sea-squirt" patented technology

The invention discloses a preparation method for polyaniline-coated sea squirt nano-cellulose conductive paper through in situ polymerization. The method comprises the following steps: subjecting extracted sea squirt cellulose to acid hydrolysis so as to prepare a sea squirt nano-cellulose suspension; then fully mixing an aniline monomer with the suspension, adding an oxidizing agent and an acid-doped mixed liquor and carrying out in situ polymerization so as to prepare a polyaniline-coated sea squirt nano-cellulose suspension; and subjecting the polyaniline-coated sea squirt nano-cellulose suspension to drying and film formation so as to obtain the sea squirt nano-cellulose conductive paper. The sea squirt nano-cellulose conductive paper prepared by using the method has the characteristics high conductivity, low cost, a simple synthetic method, low toxicity, etc.

The invention relates to a method for extracting microcrystalline cellulose from sea squirts and preparing lyotropic cholesteric crystal, which comprises the steps of: soaking the sea squirts with distilled water, cleaning and only reserving tunics with thin skin scraped out; soaking the tunics with strong base for 6-24h to remove protein and lipid; subjecting the tunics in a buffering solution at 40-90 DEG C to reaction for 1-5h, and repeating the step 2-8 times; placing obtained cellulose on watch glass for drying; crushing to a micrometer or millimeter level; pouring into a beaker containing a proper amount of concentrated acid for hydrolysis, stirring to react for 30min-6h, and adding a large amount of distilled water again for terminating the reaction; and repeatedly centrifuging and dialyzing to remove acid in suspension so as to ensure that the solution outside a dialysis bag to be neutral or subacid finally, and then evaporating for concentration to obtain the lyotropic cholesteric crystal. The method has simple reaction processes, easier control of technological method, rich raw material resources, low cost, good repeatability, environmental protection, no toxicity and lower cost, is easier for mass production, and can be applied to industrial production.

The low-cost preparation method for polypeptide sea squirts with sequence as formula (I), 666.3 molecular weight and anti-HBV function comprises: dipping with ethanol at normal temperature to prepare extract after ethanol recovery; extracting the extract with organic solvent to condense, separate and purify by in turn the chromatography with macroporous resin, silica gel with gradient elution with CHCl3, MeOH and H2O by ratio as 7:3:0.5, and Sephadex LH20; collecting and condensing the eluent with Rf as 0.2-0.3 for ultraviolet detection label in TLC.

The invention discloses a method for preparing gamma-linolenic acid-rich grease through sea squirt-associated Penicillium citrinum Asc2-4 fermentation. The method comprises inoculating a fermentation medium with sea squirt-associated Penicillium citrinum Asc2-4, carrying out fermentation under the oxygen condition to obtain Penicillium citrinum mycelia, and extracting gamma-linolenic acid-rich grease from the Penicillium citrinum mycelia. The sea squirt-associated Penicillium citrinum Asc2-4 is preserved in the Guangdong microbiology culture center (GDMCC) On July 16, 2016 and has a preservation number of GDMCC NO: 60059. The method utilizes an easily available medium, has stable fermentation conditions and has simple processes and a high yield. The produced grease has high unsaturated fatty acid oil content and especially has high gamma-linolenic acid content. The gamma-linolenic acid can be used for production of foods, medicines and cosmetics, has a wide application range and has a good promotion and application prospect.

The invention discloses a preparation method of a sea squirt nano cellulose ultrafiltration membrane. According to the method disclosed by the invention, sea squirt nano cellulose water suspension is prepared by using an acidolysis method; a common filter membrane is used as a substrate; the sea squirt nano cellulose water suspension is pumped and filtered to form the ultrafiltration membrane. The pore diameter size of the ultrafiltration membrane can be controlled through electrolytes including an acid, an alkali and salt and the like, so that micro-nano particles with different sizes are separated. The invention further discloses application of the ultrafiltration membrane in the aspects of protein concentration, oil-water separation and the like. The sea squirt nano cellulose ultrafiltration membrane prepared by the scheme can be used for effectively separating emulsified oil from proteins, and the preparation method is simple and feasible and low in cost, and has no toxin.

[Problem] Fucoxanthin extracted from wakame seaweed (Undaria pinnatifida) is effective as an anti-obesity active agent. However, fucoxanthin is contained in mature (adult) brown algae in a small amount, and accordingly, it takes a long time and high cost to obtain fcoxanthin in an amount sufficient for practical use. Further, an anti-obesity active agent showing a stronger effect has been desired. It is, therefore, an object of the present invention to specify a carotenoid exhibiting anti-obesity activity stronger than that of fucoxanthin and to provide an anti-obesity active agent and an anti-obesity method which use the caritenoid.[Means to Solve the Problem] Intensive and extensive studies have been made as to what carotenoid has an anti-obesity activity stronger than that of fucoxanthin and what material should be used in order to economically obtain such a carotenoid. As a result, the answer has been found that the carotenoid is fucoxanthinol. “Sea squirt (ascidian)” is a generic name of marine animals which belong to class Ascidiacea, subphylum Urochordata (Tunicata), phylum Chordata and which live nationwide. As described above, sea squirt (ascidian) is abundantly found as resources. In the present invention, fucoxanthinol is extracted particularly from internal organs and hard skins of sea squirt (ascidian), and it has been revealed that fucoxanthinol exhibits strong anti-obesity activity.

The invention relates to an artificial optimized culture method for sea squirts, microalgae and stichopus japonicus. The artificial optimized culture method for sea squirts, microalgae and stichopus japonicus is a bio-remediation technology for realizing self-purification of a culture water body and a sustainable marine product culturing method by utilizing a biological mutual benefit mechanism of a seawater polyculture system. The bait microalgae are inoculated in culture seawater; and the stichopus japonicus and the sea squirts are put into the culture water body with increased microalgae biomass. The inorganic nutritive salt in the seawater is converted into the microalgae biomass through the bioconversion of the microalgae so as to provide abundant bait for cultured organisms and simultaneously increase the concentration of dissolved oxygen in the water body. The sea squirts filtrate a large amount of sea water to remove grains and excess microalgae in the water body and settle a large quantity of aqueous layer particulate organic matters into a substrate in the form of feces and false faces. The demersal stichopus japonicus with a detritus food habit ingest the organic debris, benthic diatoms and microorganisms in the substrate so as to improve a substrate environment and reduce water body pollution. The artificial optimized culture method for sea squirts, microalgae and stichopus japonicus utilizes the polyculture system to promote the culture proliferation of the stichopus japonicus, carry out the self-purification and remediation of the culture water body, and realize the sustainable development of stichopus japonicus culture industry.

The invention relates to the technical field of cloud computing, in particular to a cloud task scheduling method, device, equipment and storage medium based on a Saussurea involucrata group. The method comprises the following steps: acquiring a to-be-scheduled cloud task set and a cloud resource set, and establishing a sea squirt group according to the cloud task set and the cloud resource set; fitness calculation is carried out on all the dolio-sea squirt individuals in the dolio-sea squirt group, and position information updating is carried out on all the dolio-sea squirt individuals in thedolio-sea squirt group according to the calculation result; fitness calculation is conducted on all the dolio-sea squirt individuals with the updated position information, and a fitness calculation result is obtained; according to a fitness calculation result, determining a target sea squirt individual with the maximum fitness value, and taking the current position information of the target sea squirt individual as a task scheduling optimal solution; and scheduling the cloud tasks in the cloud task set to the cloud resources corresponding to the cloud resource set according to the task scheduling optimal solution. According to the invention, multi-objective balanced optimization of cloud task scheduling is realized.

The present invention relates to a traditional Chinese medicine composition for treating chronic gastritis and enteritis. The composition is prepared from the following Chinese medicine raw materials by weight: 10 g of radix curcumae; 11 g of magnolia obavata; 15 g of fruit of immature citron; 18 g of malt; 8 g of coptis chinensis franch; 14 g of angelica sinensis; 10 g of white conioselium chinensis; 13 g of the root bark of the peony tree; 22 g of endothelium corneum gigeriae galli; 18 g of sea squirt; 14 g of fructus amomi; 10 g of fructus amomi rotundus; 12 g of citrus chirocarpus; 15 g of licorice; 16 g of fried white atractylodes rhizome; 25 g of ginseng; 28 g of white hyacinth bean; 14 g of poria; and 17 g of the fruit of Chinese wolfberry. The use of each medicine is resulted from a plurality of clinical prescriptions. By taking the medicine, the medicine starts from the human body overall, treats both symptoms and root causes, has the effects of moving qi and warming the middle, promoting digestion and invigorating the stomach, relaxing tension and relieving pain, astringing and stopping bleeding, and cooling blood and detoxifying. Proved by hundreds of clinical trials, the medicine has obvious treatment effect on the treatment of chronic gastritis, and the cure rate is high.

The invention discloses Ganji san and a preparation method thereof; the ingredients of the Ganji san are as follows by weight parts: 3-10 parts of rangooncreeper fruit, 3-10 parts of Chinese gall, 3-10 parts of sea squirt, 3-10 parts of liquorice, 3-10 parts of narcissus, 3-10 parts of semen brassicae, 3-10 parts of common yam rhizome, 3-10 parts of red orpiment, 0.1-1 part of cinnabar and 0.1-0.6 part of mercurous chloride; the preparation steps of the Ganji san are as follows: the rangooncreeper fruit, the Chinese gall, the sea squirt and the liquorice are placed in an oven for being baked for 1-3 minutes; and then the narcissus, the narcissus and the common yam rhizome are added in for being baked for 20-60 seconds and are taken out; the red orpiment is powdered, and is mixed with the cinnabar and the mercurous chloride and the other raw materials, and then the mixture is crushed; the powder is sterilized and is packed into bags with 5g each one.

The invention discloses a preparation method of sea squirt low molecular polypeptides. The preparation method comprises the following steps: immersing and cleaning sea squirts, crushing the sea squirts by using a crusher, adding to an industrial grade colloid mill, carrying out ultramicro crushing to a particle size of 30-50mum, uniformly mixing with water having a volume 2-6 times the volume of obtained particles, adding to a centrifuge, continuously centrifuging at 8000-12000rpm for 30min, removing the obtained supernatant, adding the obtained precipitate and water having a volume 2-6 times the volume of the obtained precipitate to a biological enzymatic hydrolysis pot, carrying out enzymatic hydrolysis under conditions comprising a temperature of 37-55DEG C and a pH value of 7.5-8.0 for 2-6h, processing the obtained enzymatic hydrolysis product by a 2KD ultrafilter membrane, carrying out nanofiltration membrane concentration of the part having a molecular weight below 2KD in the product, and carrying out spray drying to obtain the finally-finished sea squirt low molecular polypeptides, wherein the addition amount of a composite enzyme in the above enzymatic hydrolysis reaction is 0.2-2% of the amount of a raw material. The part having a molecular weight above 2KD in the enzymatic hydrolysis product returns to the biological enzymatic hydrolysis pot for enzymatic hydrolysis.

The invention discloses an energy-optimized virtual machine deployment method and system. The method comprises the following steps: step 1, determining a virtual machine deployment target and constraint conditions thereof; 2, determining deployment solution calculation initialization parameters; step 3, population initialization is carried out, so that the dolio-sea squirt individuals are in one-to-one correspondence with deployment solutions of the virtual machines; 4, according to the virtual machine deployment target and the constraint conditions of the virtual machine deployment target, calculating the fitness of each scabbard individual in the initialized population; 5, determining a food source, a leader and a follower to obtain an updated population; 6, calculating and updating thefitness of each scabbard individual in the population, and determining a food source; and 7, repeating the steps 5-6, and outputting the food source position in the current population as a final virtual machine deployment optimal solution. According to the method, exploration behaviors and development behaviors in the iteration process are balanced through the group optimization model of the Sashimi, and the virtual machine deployment effect of energy optimization is achieved while the globality and diversity are guaranteed.

The invention relates to the technical field of bionics application, and particularly discloses an underwater bionic sea squirt soft robot which comprises an integral shell, a plurality of bubble drivers, a controller and a storage battery; the bubble drivers are arranged outside the integral shell, and the controller and the storage battery are arranged inside the integral shell; each bubble driver comprises a bubble shell, an elastic skin, a magnet and an electromagnet, wherein one end of the bubble shell is connected with the integral shell and is provided with the magnet, the other end ofthe bubble shell is an elastic surface, the electromagnet is arranged on the elastic surface, and an opening used for draining water and feeding water is further formed in one side of the bubble shell; the controller is connected with the electromagnets and the storage battery and used for controlling power-on and power-off of the electromagnets, and the electromagnets can interact with the magnets to generate relative motion so as to drive the elastic skins to deform. The problems that in the prior art, an underwater robot is large in driving noise, large in size, low in concealment and the like are solved.

The invention discloses sea squirt-associated Penicillium citrinum Asc2-4. The sea squirt-associated Penicillium citrinum Asc2-4 is preserved in the Guangdong microbiology culture center on July 16, 2016 and has an accession number GDMCC NO: 60059. The sea squirt-associated Penicillium citrinum Asc2-4 is high gamma-linolenic acid yield filamentous fungus which is separated from sea squirt internal organs and is purified based on a potato extract glucose medium. The sea squirt-associated Penicillium citrinum Asc2-4 has a fast growth speed and strong vitality. The grease prepared through the sea squirt-associated Penicillium citrinum Asc2-4 fermentation has high gamma-linolenic acid content. The sea squirt-associated Penicillium citrinum Asc2-4 has a good industrial application prospect.

The invention discloses a sea squirt cellulose blending modified pullulan-grafted pineapple fiber packaging film. The packaging film is prepared from, by weight, 115-120 parts of pineapple leaf fiber, 5.6-6 parts of composite cellulase, 2.8-3 parts of nanometer magnesia particles, 4.3-4.4 parts of citric acid, 18-19 parts of sea squirt cellulose, 21-22 parts of pullulan, 4-5 parts of carbon nanotube-TiO2 composite material, 5-6 parts of polygonum cuspidatum extract, 11-12 parts of bamboo fiber, 17-18 parts of superfine starch, 4-5 parts of glyceryl stearate, 2-3 parts of kappa carrageenan, an appropriate amount of water and an appropriate amount of deionized water. According to the packaging film, the pullulan which is grafted with the carbon nanotube-TiO2 composite material and subjected to blending modification of sea squirt cellulose is adopted for combining a nanosized pineapple leaf cellulose solution and other ingredients, all the materials are subjected to ultrasonic-assisted emulsifying shearing to prepare a homogeneous film solution which is used for preparing the pineapple cellulose film, and the pineapple cellulose film has certain antibacterial and light degradation properties and good air permeability, stretching resistance and fracture resistance.

The invention discloses a pair of quinazolinone alkaloid enantiomers, and a preparation method and application thereof. Penicillium canescens SYSU-MS4829 is preserved in the Guangdong Microbial Culture Collection Center on July 11, 2018 with the preservation number of GDMCC 60402, and the Penicillium canescens SYSU-MS4829 can ferment to produce compounds with the structures shown in a formula (I)and a formula (II) (please see the specification for the formula (I) and the formula (II)). The Penicillium canescens SYSU-MS4829 is isolated from sea squirts in Daao Bay, Shenzhen, and can metabolizeto produce the compound quinazolinone alkaloid enantiomers (+ / -)-penicamide A with the anti-inflammatory activity, optical voidness compounds (+)-penicamide A and (-)-penicamide A obtained after division of the Penicillium canescens SYSU-MS4829 have the same good anti-inflammatory effect and both can effectively inhibit production of NO by an LPS-induced inflammatory cell RAW264.7, and IC50 is 35.1 [mu]M, 47.5 [mu]M and 27.2 [mu]M respectively; meanwhile, all compounds have no cellular poison to the cell RAW264.7; therefore, a racemic compound (+ / -)-penicamide A and the optical voidness compounds (+)-penicamide A and (-)-penicamide A have good potential as anti-inflammatory drugs and can be used for preparing anti-inflammatory drugs.

The invention discloses a sea squirt polypeptide pharmaceutical composition as well as a preparation method and application thereof. The composition comprises the following components in parts by weight: 0.001-0.01 parts of sea squirt polypeptide (the amino acid sequence is LysGlyLysIle Glu His) and 5-8 parts of phyllanthus urinaria alcohol extract. The invention further discloses application of the sea squirt polypeptide pharmaceutical composition in the preparation of medicine for treating hepatitis B. By adopting the sea squirt polypeptide pharmaceutical composition, relatively good drug synergism is played from pharmacological functions of multiple points, and the disadvantage of simple recipe is overcome.

The invention discloses a cancer treatment drug which comprises sea squirt polypeptide and cis-platinum. The invention further discloses an application of a combination of the sea squirt polypeptide and the cis-platinum in preparation of the cancer treatment drug. The combination of the sea squirt polypeptide and the cis-platinum shows an obvious synergetic effect and can improve treatment efficacy of the cis-platinum on a liver cancer patient and life quality of the liver cancer patient. The combined medication scheme provides a new treatment clue and a scheme for clinical liver cancer treatment and has great development potentials and application prospects for the clinical liver cancer treatment.

The invention relates to a medicament for treating gastropathy, which is prepared from traditional Chinese herbs of radix bupleuri processed with vinegar, cynanchum glaucescens, Chinese angelica, roasted white atractylodes rhizome, poria, mint, fructus aurantii, radix curcumae, peony tree root bark, fructus gardeniae, motherwort, roasted rhizoma atractylodis, uncooked wheat seed, roasted Chinese yam, sea squirt, rhizoma corydalis, golden cypress, Tribulus terrestris L, liquorice and the like. The medicament can be made into capsules and can sooth the liver and regulate vital energy, regulate stomach and relieve pan and has good treatment effect on gastritis, hyperacidity, bad appetite and the like without any obvious side effects.

The invention belongs to the technical field of biological medicines, and particularly relates to an isaridin cyclic ester peptide derivative as well as a preparation method and application thereof. Tests prove that the derivative shows good anti-inflammatory and antithrombotic activity, even the activity is higher than that of a positive control drug, in addition, a natural compound derived from marine microorganisms has the characteristics of difficulty in resistance generation, high safety and the like, and tests also prove that the cytotoxicity of the compound disclosed by the invention is low. Meanwhile, the isaridin cyclic depsipeptide derivative disclosed by the invention is extracted from sea squirt-associated epiphytic fungi, can be fermented on a large scale by utilizing microorganisms, has the characteristics of simple production process, short period, low product cost and the like, and has a wide application prospect.

The invention discloses a preparation method of a sun-proof clothing material. According to the technical scheme, the preparation method comprises the following steps of extracting sea squirt cellulose from the tunica of sea squirt, then mixing the sea squirt cellulose with cotton cellulose according to a certain proportion, adding a mixture into a solution of butyl titanate and absolute ethyl alcohol, and then adding a softener and 2, 2', 4, 4'-tetrahydroxybenzophenone, and performing ultrasonic stirring, filtration, washing and drying to obtain the sun-proof clothing material. The sun-proofclothing material prepared by the method can prevent ultraviolet radiation, can also reflect infrared rays (heat energy), and also has the advantage of comfortable wearing.

The invention discloses a preparation method and a product of sea squirt cellulose fiber spinning solution. The spinning solution is prepared by placing sea squirt cellulose in a proper solvent and dissolving and defoaming under the conditions of certain temperature and stirring. The sea squirt cellulose has a rich raw material resource; and the preparation process of the sea squirt cellulose fiber spinning solution has the advantages of simplicity, environmental friendliness, good repeatability, easiness in large-scale production, low cost and suitability for industrial production.

The invention relates to a wireless channel attenuation model fitting method based on a quantum sea squirt group. The wireless channel attenuation model fitting method specifically comprises the following steps: setting the parameters of the Nakagami-m distribution and obtain an accurate data set of the Nakagami-m inverse cumulative distribution; initializing the quantum position and position of the sea squirt group;; carrying out fitness evaluation on all sea squirt positions, and determining the quantum position and position of the food; updating the quantum rotation angle, the quantum position and the position of the selected sea squirt in sequence according to the first strategy or the second strategy; Sequentially updating the quantum rotation angle, the quantum position and the position of the selected sea squirt according to a third strategy; Carrying out fitness evaluation on all sea squirt positions, and updating the quantum position and position of the food; Wherein the finally output food position is the optimal coefficient of the fitting equation, and obtaining the Nakagami-. And m is an optimal fitting equation of the inverse cumulative distribution function. The method has the advantages of higher fitting precision, higher fitting speed and wider application range.

The invention provides a preparation method of a sea squirt compound and an intermediate thereof, and particularly provides a preparation method of a novel compound QT9 and a method for preparing thesea squirt compound by using the QT9. The method is high in reaction selectivity and high in yield, the obtained compound is easy to purify, the defects that a plurality of intermediates are oily substances and the reaction selectivity is poor in the prior art are overcome, and the method is particularly suitable for industrial production.

The invention discloses a method for preparing a sea squirt nanocrystalline cellulose / rubber nanocomposite with a one-pot process. According to the method, natural latex is diluted at the room temperature, and an emulsifier is slowly dropwise added; a sea squirt nanocrystalline cellulose suspension and emulsified natural latex are blended, and a premix is obtained; formic acid is slowly dropwise added to the premix, and hydrogen peroxide is slowly added for a reaction; after the reaction ends, the pH value is adjusted to 6-8, solidification, blanching, dewatering and drying are performed, and a sea squirt nanocrystalline cellulose / rubber mixture is obtained; the mixture and a vulcanizing agent are mixed in an open mill and left for vulcanizing formation. The problem of poorer strength due to physical interaction of two interfaces in the prior art is solved, and the prepared rubber nanocomposite has excellent properties such as high strength, high modulus, high wear resistance and the like and can more sufficiently play the strengthening effect of nanocrystal cellulose.

The invention discloses a sea squirt antioxidant polypeptide and a preparation method thereof. The amino acid sequence of the antioxidant polypeptide is Ile-Ser-Trp. The preparation method comprises the following steps: carrying out enzymolysis on sea squirt inner capsule meat blocks serving as a raw material by using compound protease, separating, purifying, and freeze-drying to obtain the antioxidant polypeptide. The antioxidant polypeptide relieves side effects possibly caused by artificial antioxidants, provides a new natural antioxidant, and can replace traditional synthetic food antioxidants.