75 results about "Alternaria" patented technology

The invention belongs to the technical field of microorganisms, and particularly relates to application of utilizing alternaria alternata to ferment pericarpium citri reticulatae so as to improve the content of total flavonoids and hesperidin in pericarpium citri reticulatae, which comprises the following steps: culturing alternaria alternata spore suspension in a PDB liquid culture solution to obtain alternaria alternata inoculation liquid; uniformly mixing the sterilized pericarpium citri reticulatae powder and the sterilized rice powder, adding the alternaria alternata inoculation liquid, fully and uniformly mixing, and then adding sterilized water; after uniform stirring, the mixture is placed in a constant-temperature incubator to be fermented and co-cultured, the fermentation temperature is 25-35 DEG C, and the fermentation time is 5-12 days. According to the method disclosed by the invention, the efficient capability of the alternaria alternata in the aspect of converting flavonoid components in the pericarpium citri reticulatae can be fully exerted, so that the content of total flavonoids and hesperidin in the pericarpium citri reticulatae is remarkably increased.

The invention discloses a pH and temperature dual stimulation response controlled release curcumin nano-pesticide and a preparation method and application thereof.The nano-pesticide comprises a carrier and curcumin loaded on the carrier, the carrier is N-isopropylacrylamide modified mesoporous silica, and the curcumin is a mixture of N-isopropylacrylamide modified mesoporous silica and N-isopropylacrylamide modified mesoporous silica and N-isopropylacrylamide modified mesoporous silica. N, N-isopropylacrylamide is polymerized on the surface of mesoporous silica through a polymerization reaction, and the preparation method comprises the following steps: (1) preparing a curcumin solution, adding modified mesoporous silica powder, fully dispersing, and slowly stirring at 20-25 DEG C under a dark condition until all white nanoparticles become yellow; and (2) collecting the nano-particles in the solution in the step (1), and drying to obtain the modified mesoporous silica drug-loaded particles. According to the curcumin nano-pesticide disclosed by the invention, the carrier N-isopropylacrylamide modified mesoporous silica is introduced, so that the stability, the leaf surface adhesion capability and the bactericidal performance on alternaria longibrachiata of curcumin are improved.

The application discloses application of BoDMR1 and BoDMR6 genes in cultivating disease-resistant broccoli varieties, an expression vector and a cultivating method, and relates to the technical field of plant molecular biology. A nucleotide sequence of a broccoli BoDMR1 gene is shown in SEQ ID No: 7, or a nucleotide after gene mutation of the nucleotide sequence shown in SEQ ID No: 7; and a nucleotide sequence of a broccoli BoDMR6 gene is shown in SEQ ID No: 8, or a nucleotide after gene mutation of the nucleotide sequence shown in SEQ ID No: 8. Through gene editing on endogenous BoDMR1 and / or BoDMR6 genes of plants, mutant plants showing resistance to diseases such as sclerotinia, black rot and alternaria blight can be obtained. Therefore, the application is beneficial to providing good resources for cultivating disease-resistant broccoli varieties.

The application discloses a bacillus velezensis A13 wettable powder and application thereof, and belongs to the technical field of biological pesticides. The application aims to solve the problems of limited prevention and treatment effect of existing seed treatment, high labor intensity of foliar spraying and short effective period. The wettable powder comprises a mother powder prepared from fermentation liquor and diatomite, and a dispersant, a wetting agent, a stabilizer and a protective agent, wherein the total addition amount of the dispersant and the wetting agent is 5%-14% of the mass of the mother powder, the addition amount of the protective agent is 0.5%-2% of the mass of the mother powder, and the addition amount of the stabilizer is 1%-3% of the mass of the mother powder. The application can be used for preventing and treating root diseases caused by panax quinquefolius rust rot fungus and leaf diseases caused by panax quinquefolius alternaria leaf spot fungus, and promoting plant growth.

The present invention provides a method for establishing a subcutaneous specific immunotherapy model of Alternaria allergic asthma mice using Alt a 1. The method comprises S1, using Alternaria crude extract (Alternaria) to perform nasal drops for sensitization and stimulation of mice; S2, using Alternaria, rAlt a 1 or nAlt a 1 protein to perform SCIT on the sensitized and stimulated mice respectively; S3, using Alternaria again to perform nasal drops for stimulation of the mice that have received SCIT. The method has a simple operation method, a moderate modeling time, a good model effect, and high repeatability, and is expected to be further promoted and used.

The invention relates to a preparation for preventing and / or treating sugarcane leukosis and application thereof, and relates to the technical field of biological agents. The preparation comprises bacillus mucilaginosus, bacillus megatherium, bacillus laterosporus, alternaria tenuissima activator protein, calcium acetate, magnesium sulfate and glucose. The preparation has a relatively good prevention and / or treatment effect on the sugarcane bacterial leaf streak, and also can promote the growth of the sugarcane at the same time.

The invention discloses a Mitschhia pastoris strain for delaying early leaf falling of pears and application of the Mitschhia pastoris strain, and belongs to the technical field of microorganisms. The preservation number of the strain is CGMCC (China General Microbiological Culture Collection Center) NO.31969, and the preservation date is September 13, 2024. The invention has the following beneficial effects: the provided metschhia pastoris is separated from the surface of healthy pear fruit, is harmless to human body, has high safety, has strong bacteriostatic activity, and can effectively inhibit the growth of pear early leaf falling pathogenic bacteria such as fruit-growing anthracnose, alternaria alternata and clostridium microneoshell. The plant senescence retardant overcomes the defects of an existing plant growth regulator, and the application range of the plant senescence retardant is widened.

The present application relates to a kind of new compound and its preparation method and application, specifically 1-substituted phenyl-5-methyl-1 H Preparation and application of pyrazole-3-formamide derivatives. The structural formula of the compound 1-substituted phenyl-5-methyl-1 H Pyrazole-3-formamide derivatives is as shown in formula I. Wherein, R1 selected from: 4-chloro or 2,4-dichloro;R2 selected from: H, methyl, methoxy, cyclopropyl;R3 selected from: 3-methylphenyl, 3-nitrobenzyl, 4-nitrobenzyl, 4-chlorophenyl, 2-(5-chloro-1 H Indole-3-yl) ethyl, N-(4-chlorophenyl)-2-phenyl. Test shows that the compound of the application shows good antifungal activity to grape cavity fungus (Botryosphaeria dothidea) (Botryosphaeria dothidea), Pythium aphanidermatum (Pythium aphanidermatum), Fusarium oxysporum (Fusarium oxysporum), Gray pear spot fungus (Gymnosporangium japonicum), Alternaria alternata (Alternaria alternata), Sclerotinia sclerotiorum (Sclerotinia sclerotiorum), Botrytis cinerea (Botrytis cinerea), and has wide application prospect. Botryosphaeria dothidea Pythium aphanidermatum Fusarium oxysporum Phyricularia grisea Alternaria nees Sclerotinia sclerotiorum Botrytis cinerea ​​​​​​​

This invention belongs to the field of biotechnology, specifically disclosing a rapid sporulation method for *Alternaria ginseng*. The method involves activating and culturing *Alternaria ginseng* in PDA medium at 25°C in the dark for 10 days. Mycelial cakes are then collected from the colony edges using a punch. These mycelial cakes are inoculated onto a sporulation medium and cultured in a sealed dark environment at 22°C for 4 days. After making crisscross cuts 1 cm from the center of the colony, the cells are treated with ultraviolet light for 9 minutes. The culture dish is then left uncovered and placed at 22°C. Finally, the cells are cultured in a light incubator at 70% relative humidity for 12 hours followed by 12 hours in the dark, resulting in rapid sporulation at the cuts. Compared to existing technologies, this invention significantly shortens the sporulation cycle (5 days), greatly saving time and costs.

This invention belongs to the field of pharmaceutical technology, and relates to the use of a combination of sour cherry powder and celery seed powder, and complexes containing this composition. Specifically, the sour cherry powder and celery seed powder composition is used in the preparation of drugs for treating or regulating intestinal flora imbalance caused by hyperuricemia. The preparation method of this composition is as follows: pitting sour cherries, freezing them separately with liquid nitrogen, grinding them into powder using a pulverizer, and sieving them separately to obtain sour cherry powder and celery seed powder; mixing the obtained sour cherry powder and celery seed powder at a ratio of (0.5~3):1. This invention discusses the diversity, richness, and evenness of intestinal flora through diversity analysis, community bar chart analysis, and Venn diagram analysis. The results show that this composition can increase beneficial bacteria (Prevotella, Mulliez, Lactobacillus, etc.), reduce harmful bacteria (Alternaria), improve the structure of intestinal flora, and maintain the balance of intestinal flora.

The invention discloses a chenopodium ambrosioides seed endophytic fungus Alternaria alstroemia HZ132. The endophytic fungus Alternaria alstroemia HZ132 is preserved in Guangdong Microbial Culture Collection Center with the preservation number of GDMCC No. 66913, and the preservation number of the endophytic fungus Alternaria alstroemia HZ132 in Guangdong Microbial Culture Collection Center is GDMCC No. 66913. The strain has strong capabilities of solubilizing phosphorus, producing indoleacetic acid, producing siderophores and resisting cadmium, is inoculated with HZ132 under cadmium stress, can significantly promote plant growth and enhance cadmium resistance of plants, and has important significance in plant-microorganism combined remediation of heavy metal contaminated soil.

The present disclosure provides a method for reducing methane emissions from a ruminant comprising administering to the ruminant a composition comprising a fungal strain, biomass from the fungal strain, a culture supernatant from the fungal strain wherein the fungal strain comprises at least one vanadium-dependent haloperoxidase (VHPO) with an amino acid sequence having at least 80% identity with an amino acid sequence selected from the group consisting of SEQ ID NOs: 3-100 and a combination thereof. The present disclosure also provides a method for reducing methane emissions with a fungal strain belonging to a genus selected from the group consisting of Alternaria, Ascomycota, Bipolaris, Cadophora, Cladorrhinum, Clohesyomyces, Darksidea, Didymella, Dothideomycetes, Drechslera, Exserohilum, Epicoccum, Exophiala, Gaeumannomyces, Gliomastix, Helotiales, Keissleriella, Laburnicola, Lachnum, Leptodontidium, Magnaporthiopsis, Mollisia, Neocamarosporium, Oidiodendron, Ophiosphaerella, Penicillium, Phaeosphaeria, Phialophora, Phoma, Pleosporales, Poaceascoma, Septoriella, Slopeiomyces, Sordariales, Trametes, Trematosphaeria, Trichoderma, and Tricladium.

The invention provides a Trichoderma harzianum strain, which is named Trichoderma harzianum, is preserved in China General Microbiological Culture Collection Center (CGMCC), has a preservation number of CGMCC No.41725, and has a preservation date of December 20, 2024. The Trichoderma harzianum strain is named as Trichoderma harzianum, is preserved in China General Microbiological Culture Collection Center (CGMCC), and has a preservation number of CGMCC No.41725. The sequence of the rDNA-ITS is as shown in SEQ ID NO: 1; the sequence of TEF-1alpha is as shown in SEQ ID NO: 2, and the sequence of RPB2 is as shown in SEQ ID NO: 3. The trichoderma harzianum strain disclosed by the invention can be used for inhibiting the activity of E. tucutricum, B. sorokiniana, A. alternania and B. zecoola, can be used for generating auxin and gibberellin, and can be used for promoting the growth of silage corn and preventing and treating the leaf spot disease of the corn alternaria in alpine regions of Qinghai province. The trichoderma harzianum strain disclosed by the invention has the advantages that the activity of the E. tucutricum, the B. sorokiniana, the A. alternania and the B. zecoola can be inhibited, and the growth of the silage corn can be promoted.

The invention relates to a biofungicide based on the bacterium Pseudomonas lini strain S57, RGM 2930 CChRGM (Chilean Collection of Microbial Genetic Resources) for agricultural use, especially in saline-boric environments. The biofungicide can be developed as solid and liquid formulations. Where the strain S57, has fungicidal properties against the phytopathogenic fungi Botrytis cinerea. Fusarium oxysporum, Monilinia fructicola, Alternaria sp., Geotrichum candidum, and Macrophomina phaseolina, both in the presence and absence of saline-bone conditions.

The invention discloses antibacterial protein from bacillus amyloliquefaciens BS-3 and application of the antibacterial protein, and belongs to the technical field of microorganisms and genetic engineering. The invention discloses a bacteriostatic protein from bacillus amyloliquefaciens BS-3. The amino acid sequence of the bacteriostatic protein is as shown in SEQ ID NO. 7. The antibacterial protein from the bacillus amyloliquefaciens BS-3 can inhibit colletotrichum acutatum, alternaria rubra and pestalotiopsis microspora.

The invention belongs to the technical field of agriculture, and particularly relates to a degerming and seedling formation solution, a preparation method, an application method and a method for promoting seed germination and seedling formation. The degerming and seedling formation solution provided by the invention comprises gibberellic acid, indoleacetic acid, naphthylacetic acid, coptis chinensis and carbendazim, and the combination of coptis chinensis extract, carbendazim and growth hormone (gibberellic acid, indoleacetic acid and naphthylacetic acid) in a specific proportion has a synergistic inhibition effect on alternaria alternata and has a promotion effect on seed germination and seedling formation. The invention provides the preparation method of the degerming and seedling forming solution, and the application is simple. According to the application method of the degerming and seedling forming solution, the operation steps are simple, convenient and efficient, and the seedling forming efficiency is remarkably improved. The result of the embodiment shows that the germination rate of the Sinojackia xylocarpa seeds reaches 100% after the optimal treatment is performed for 15 days, and the survival rate of the seed seedlings reaches 96.67% after the optimal treatment is performed for 30 days.

This invention belongs to the field of biological agent technology, specifically relating to a strain of *Trichoderma*, a biocontrol agent, a bio-organic fertilizer, and methods and applications for controlling plant diseases. This invention provides a strain of *Trichoderma* P11, with accession number CCTCC NO: M 2024648. The *Trichoderma* P11 of this invention can enhance positively correlated disease resistance genes in plants. PnCAD , PnSN1 , PnDEFL1 The relative expression level of *Trichoderma* P11 was increased, enhancing the activity of disease resistance-related enzymes SOD, POD, and CAT. Furthermore, *Trichoderma* P11 could damage the cell membrane of pathogens, inhibiting their growth. *Trichoderma* P11 also exhibits good rhizosphere colonization ability. The results of the examples show that *Trichoderma* P11 of the present invention can reduce the incidence of root rot in Panax notoginseng fields and can also antagonize various pathogens such as *Pseudomonas aeruginosa*, *Pseudomonas oryzae*, *Geotrichum candida*, *Early Blight of Tomato*, *Phytophthora indicum*, *Phytophthora capsici*, and *Alternaria spiralis*.

The invention relates to the technical field of molecularly imprinted polymers of alternaria toxin, in particular to a multi-monomer molecularly imprinted polymer of alternaria toxin and a preparation method and application thereof.The preparation method comprises the steps that template molecules, functional monomers, a cross-linking agent and an initiator with the required amount are mixed step by step and then subjected to ultrasonic treatment and prepolymerization, and a prepolymerization mixed solution is obtained; carrying out water bath heating on the pre-polymerized mixed solution, and then carrying out polymerization reaction to obtain a polymerization product; and eluting and drying the polymerization product to obtain the multi-monomer alternaria toxin molecularly imprinted polymer. The multi-monomer molecularly imprinted polymer is prepared by taking the alternaria toxin or a structural analogue thereof as a template and polymerizing functional monomers, and the multi-monomer molecularly imprinted polymer of the alternaria toxin is uniform spherical particles, large in specific surface area and provided with a large number of pores, has high selectivity, rapid combination and strong enrichment capacity on the alternaria toxin, and can be used for preparing the multi-monomer molecularly imprinted polymer of the alternaria toxin and the preparation method of the multi-monomer molecularly imprinted polymer of the alternaria toxin. The method can be applied to the detection technology of fungaltoxin polluted by tomatoes, peppers and other fruits and vegetables, and the detection precision is improved.

The application discloses a pesticide composition containing fluopyram and application of the pesticide composition in prevention and treatment of apple alternaria leaf spot, and belongs to the technical field of pesticides. A volatile oil extract of Alpinia galanga and a volatile oil extract of Eupatorium fortunei are obtained, and in indoor tests, the colony diameters of apple Alternaria alternata are all reduced, which indicates that the volatile oil extract of Alpinia galanga and the volatile oil extract of Eupatorium fortunei can inhibit the mycelium growth of apple Alternaria alternata. The volatile oil extract is used as a synergistic extract, combined with fluopyram, and added with various additives to prepare the pesticide composition containing fluopyram. In field tests, the disease index of fruit trees is all reduced, which indicates that apple Alternaria alternata is inhibited, and the relative prevention and treatment efficiency of the compound group is the highest and reaches 80.05%. The pesticide composition containing fluopyram is prepared by compounding fluopyram and the synergistic extract containing the volatile oil extract of Alpinia galanga and the volatile oil extract of Eupatorium fortunei, the pesticide composition can better inhibit apple Alternaria alternata, and is suitable for development of a pesticide for preventing and treating apple alternaria leaf spot.

The present invention provides a salt-tolerant actinomycete in saline-alkali land and its application, named as strain NHKJ0003, which has been deposited in the General Microbiological Center of China Microbiological Culture Collection Committee on April 26, 2024, with a deposit number of CGMCC No.30450, and a deposit address of No. 3, Yard No. 1, Beichen West Road, Chaoyang District, Beijing, Institute of Microbiology, Chinese Academy of Sciences, and taxonomic name Streptomyces rochei. The strain can inhibit Fusarium oxysporum, Pseudomonas aeruginosa and Alternaria alternata. Compared with traditional chemical pesticides for preventing and controlling plant diseases, it has significant prevention and control effects, no pollution to the soil, green and environmentally friendly, and has broad application prospects.

The invention discloses a grape wine color protection method based on alternaria MG1, and belongs to the technical field of fermented wine brewing. According to the method, alternaria MG1 is taken as a research object, a phenylpropane metabolic pathway of alternaria MG1 is activated through various stimulation methods such as ultraviolet radiation, exogenous addition of oligomeric proanthocyanidins, co-culture with other endophytic filamentous fungi and the like, and the alternaria MG1 and saccharomyces cerevisiae are subjected to mixed fermentation, so that an optimal color protection process for grape wine color is explored. The invention deeply discusses the influence of the mixed fermentation on the color and the related quality characteristics of the wine, provides a new theoretical support and a process optimization strategy for the application of the multi-strain synergistic fermentation based on the grape endophyte in wine brewing, and has important guiding significance for production practice.

The present invention relates to a method for controlling or preventing infestation of a plant by a phytopathogenic microorganism of the genus Fusarium, Aceturium, Corynespora, Alternaria or Colorospora, the method comprising applying a combination or composition to the plant, its locus or its propagation material in any desired sequence or at the same time, the combination or composition comprises as component (A) a compound of formula (A-1) and as component (B) a compound of formula (B-1). Compositions suitable for use in the invention are also disclosed. (A-1) is greater than (B-1).

The invention discloses a paenibacillus polymyxa S437 strain and an application thereof. The name of the bacterial strain is Paenibacillus polymyxa S437, and the preservation number of the bacterial strain is GDMCC No: 66085. The strain S437 has a good disease prevention effect on banana soft rot, and the disease prevention effect reaches 85% or above. The bacterial strain S437 has a wider antibacterial spectrum, and can effectively inhibit the growth of various pathogenic fungi and bacteria, such as fusarium, fusarium solani and the like which cause plant basal stem rot or fusarium wilt, colletotrichum which causes plant anthracnose, and alternaria, melanospora, interphaga, fusarium and the like which cause plant leaf spot bacteria; and S437 has a good antibacterial effect on banana soft rot bacteria. The strain S437 can avoid potential adverse effects of chemical pesticides on the environment and crop safety, and has potential commercial development and application values in biological prevention and control practice of diseases.

The invention discloses a plant endophyte Microcera larvarum ML-5 and application of the plant endophyte Microcera larvarum ML-5 in prevention and treatment of carya illinoensis diseases, and belongs to the technical field of microorganism application. The preservation number of the plant endophyte is CCTCC (China Center for Type Culture Collection) NO: M 2025636, and the preservation number of the plant endophyte is CCTCC NO: M 2025636. The compound can effectively inhibit carya illinoensis black spot colletotrichum gloeosporioides, carya illinoensis leaf spot alternaria, fusarium oxysporum, white rot, fusarium oxysporum and watermelon gummy stem blight. The plant diseases caused by the pathogenic bacteria can be prevented and treated. The plants can be colonized in the plants to form a symbiotic relationship with the plants, so that the immunity of the plants is enhanced, and invasion of pathogenic bacteria is effectively resisted. The endophytic fungi can promote plant growth, improve yield and quality, and bring sustainable development to agricultural production. Therefore, prevention and treatment of diseases by using the plant endophytic fungi is an important direction of agricultural green prevention and control in the future.

The present application provides an endophytic bacterial strain with a high camptothecin yield, which is Alternaria temuissima ZCMUKL-S1, deposited as CCTCC NO: M2021189, or Alternaria citricancri ZCMUKL-S2, deposited as CCTCC NO: M2021190, or Aspergillus versicolor ZCMUKL-S3, deposited as CCTCC NO: M2021191. The endophytic bacterial strain has a high yield of camptothecin, wherein the yield of camptothecin per unit dry mycelium powder of Aspergillus versicolor ZCMUKL-S3 is as high as 116 μg / g, which is the highest yield of camptothecin produced by endophytic bacterial strains reported at present, and has potential application value for its industrial production. In addition, the endophytic bacterial strain which can produce high camptothecin provided by the present application has good genetic stability.

The invention discloses a primer combination and a kit for detecting alternaria alternata and application of the primer combination and the kit. The primer combination comprises a primer pair and crRNA, wherein the nucleotide sequence of the primer pair comprises a sequence as shown in SEQ ID NO. 1 and a sequence as shown in SEQ ID NO. 2; the nucleotide sequence of the crRNA comprises a sequence as shown in SEQ ID NO. 7. The invention also provides a kit for detecting the alternaria alternata. According to the primer combination and the kit disclosed by the invention, accurate and rapid identification of the alternaria alternata can be realized; the detection sensitivity is extremely high; in addition, the method is simple and convenient to detect, can be used for field identification of alternaria alternata and can also be used for detection of access ports, so that the method has a wide application prospect.

The invention relates to the technical field of natural antibacterial compounds, in particular to an antibacterial compound, a preparation method and application thereof and a pesticide agent. The antibacterial compound is selected from compounds shown in the following structural formula: the compound has an inhibition effect on methicillin-resistant staphylococcus aureus and other drug-resistant bacteria, staphylococcus aureus, escherichia coli, salmonella, pseudomonas aeruginosa and other bacteria, and alternaria, fusarium, colletotrichum and other fungi; the compound can be applied as broad-spectrum antibacterial, broad-spectrum antifungal and drug-resistant bacterium resistant drugs.

The invention belongs to the technical field of agricultural microorganisms, and particularly relates to bacillus BFI-L3 with a broad-spectrum antibacterial effect and application of the bacillus BFI-L3. The invention discloses bacillus velezensis BFI-L3, which is bacillus velezensis, and the preservation number of the bacillus velezensis BFI-L3 is CGMCC (China General Microbiological Culture Collection Center) No.35399. The strain has broad-spectrum antibacterial activity, has a remarkable antibacterial effect on camellia anthracnose, botryosphaeria, alternaria and other pathogenic fungi, and can synchronously prevent and control the compound diseases of the tea garden. The strain also has plant growth promoting ability, VOCs generated by the strain can significantly promote the growth of arabidopsis thaliana, and high-quality microbial resources are provided for green prevention and control of tea gardens and biological prevention and control of plant diseases.

The application relates to a Burkholderia gladioli NDG19 and an application of the Burkholderia gladioli NDG19 in disease resistance, and belongs to the technical field of microorganisms. The Burkholderia gladioli NDG19 is preserved in the Guangdong Provincial Microbial Culture Collection Center on July 31, 2023, the strain preservation number is 63701, and the preservation address is No. 59 Building, 5th Floor, Guangzhou, Guangzhou, China. The Burkholderia gladioli NDG19 provided in the application can effectively inhibit the growth and reproduction of Fusarium oxysporum and Alternaria tenuis, and can effectively prevent and treat plant fusarium wilt such as sharp banana fusarium wilt and melon root rot of cucurbitaceae crops, solves the problems of environmental pollution and food safety caused by chemical fungicides, the strain has the functions of iron carrier production, phosphorus dissolution and potassium dissolution, can effectively improve the utilization rate of phosphorus and potassium in soil as a biological bacterial fertilizer, promotes the growth of plants, is safe and environment-friendly, and has a wide application prospect.

This invention discloses a lysinibacillus macroides bacterium that degrades Alternaria alternata toxins and its applications, belonging to the field of microbial technology. The lysinibacillus macroides is deposited at the China Center for Type Culture Collection (CCTCC), Wuhan University, Hubei Province, with accession number CCTCC No. M20241816. This invention is the first to obtain a lysinibacillus macroides bacterium that can effectively reduce and degrade Alternaria alternata toxins, which helps improve the quality of agricultural products (including aquatic products).