16results about How to "Increase disorder" patented technology

The invention discloses a traditional Chinese medicine tea drink for preventing and treating oral mucosa diseases and a preparation method of the traditional Chinese medicine tea drink. The traditional Chinese medicine tea drink is prepared from 10-15 parts of radix astragali, 8-12 parts of radix codonopsis, 6-10 parts of radix salviae miltiorrhizae, 5-9 parts of radix angelicae sinensis, 3-6 parts of fructus psoraleae, 6-9 parts of rhizoma polygonati, 6-9 parts of radix adenophorae, 6-10 parts of rhizoma atractylodis macrocephalae, 5-9 parts of radix ophiopogonis, 3-5 parts of radix glycyrrhizae, 4-6 parts of pericarpium citri reticulatae and 5-8 parts of herba taraxaci. Aiming at the core pathogenesis of low immunity, long-term deficiency, long-term deficiency and kidney-yang insufficiency of patients suffering from oral mucosa diseases, qi tonifying, blood activating and kidney-qi strengthening are taken as a core treatment method, the formula is scientific and reasonable, all the medicinal materials act synergistically, the overall immune function of the body is adjusted, T lymphocyte subpopulation imbalance and cell factor network disorder are improved, and the curative effect is good. The oral mucosa microcirculation is improved, local inflammation is relieved, the immunity of a patient is improved fundamentally, the recurrence rate of oral mucosa diseases is reduced, and the problems that an existing tea drink is not high in pertinence and limited in curative effect are solved. The tea drink is appropriate in taste, good in compliance, high in safety and suitable for people with various oral mucosa diseases and low immunity.

The utility model belongs to the technical field of cooking equipment, and particularly provides a cooking utensil and a silencing component. In order to solve the problem that air noise is large when an existing cooking utensil exhausts air, the cooking utensil comprises a machine body, a machine cover and a silencing component. The machine body is provided with a cooking cavity. The machine cover is used for opening and closing the cooking cavity, and an exhaust channel is formed in the machine cover and used for exhausting gas in the cooking cavity. The silencing component is embedded into the exhaust channel, a silencing channel is defined by the silencing component and the peripheral wall of the exhaust channel, and the through-flow area of the silencing channel is alternately increased and decreased, so that the flow speed of gas is repeatedly increased and decreased, and the wind noise is reduced.

This invention belongs to the field of pharmaceutical technology, and relates to the use of a combination of sour cherry powder and celery seed powder, and complexes containing this composition. Specifically, the sour cherry powder and celery seed powder composition is used in the preparation of drugs for treating or regulating intestinal flora imbalance caused by hyperuricemia. The preparation method of this composition is as follows: pitting sour cherries, freezing them separately with liquid nitrogen, grinding them into powder using a pulverizer, and sieving them separately to obtain sour cherry powder and celery seed powder; mixing the obtained sour cherry powder and celery seed powder at a ratio of (0.5~3):1. This invention discusses the diversity, richness, and evenness of intestinal flora through diversity analysis, community bar chart analysis, and Venn diagram analysis. The results show that this composition can increase beneficial bacteria (Prevotella, Mulliez, Lactobacillus, etc.), reduce harmful bacteria (Alternaria), improve the structure of intestinal flora, and maintain the balance of intestinal flora.

The application discloses a modified polypropylene material and a preparation method and application thereof. The modified polypropylene material contains the following raw materials in percentage by mass: 25-32% of homopolymerization polypropylene, 34-42% of modified copolymerization polypropylene, 13-25% of inorganic filler, 5-13% of toughening agent, 5.4-7.5% of coupling agent and 0.4-0.6% of stabilizer; wherein, the coupling agent contains at least two primary amine groups, and the modified copolymerization polypropylene contains aldehyde groups. The modified polypropylene material has a reversible cross-linking macromolecular network structure formed by mutual cooperation between the raw materials, and has excellent comprehensive performance in the aspects of improving the strength, low-temperature resistance, toughness and processing performance of the modified polypropylene material.

The application relates to the biological field, in particular to a lactobacillus fermentum zhangweizhuang cell lysate for regulating macrophage polarization and assisting PD-1 inhibitor to inhibit liver cancer development. The ZW18 cell lysate is a cell lysate containing various metabolites prepared from lactobacillus fermentum ZW18 with a preservation number of CGMCC No. 23549 through fermentation, heat treatment and ultrasonic lysis treatment, and the metabolites at least contain active ingredients: extracellular polysaccharide of greater than or equal to 2200 mg / L, amino acid of greater than or equal to 70 mmol / L and flavonoid of greater than or equal to 150 g / L. The ZW18 cell lysate can induce M1 type polarization of macrophages, can assist PD-1 inhibitor to inhibit liver cancer development in cooperation with the PD-1 inhibitor, can regulate intestinal flora imbalance caused by liver cancer, and can be used for preparing a combined preparation with the PD-1 inhibitor.

The present application relates to a seaweed residue-based electrochemical biosensor and a preparation method thereof, which uses seaweed residue as raw material and chitosan as crosslinking agent, and prepares carbon aerogel CAs through sol-gel, vacuum freeze-drying and high-temperature carbonization process, and uses the CAs modified electrode (CAs / GCE) for DA detection. The present application uses high-temperature pyrolysis of nitrogen in seaweed residue to increase the disorder of C in CAs, which can effectively increase the active sites for dopamine detection and improve the electrochemical detection activity of the sensor for DA. CAs do not contain substances harmful to organisms or polluting to the environment, which not only solves the problems of high cost and limited application range of other raw materials, but also solves the problems of high value-added development and utilization of waste seaweed residue.

This invention discloses a method for preparing and applying crude and homogeneous polysaccharides of *Mesona chinensis* that regulate *Bacteroides*. The method includes the following steps: pulverizing *Mesona chinensis* herb, extracting by reflux with deionized water, filtering out the residue, concentrating to 1 / 4 of the volume, adding ethanol to 80% by volume, stirring evenly, letting stand overnight, centrifuging the precipitate, washing three times with anhydrous ethanol, ethyl acetate, and acetone respectively, dissolving in an appropriate amount of deionized water, and freeze-drying to obtain crude *Mesona chinensis* polysaccharide. The obtained crude *Mesona chinensis* polysaccharide is diluted with deionized water and dialyzed using dialysis bags in the range of 7000D, 100000D, 300000D, and 500000D respectively. The solutions are combined, concentrated, and freeze-dried to obtain homogeneous polysaccharides of *Mesona chinensis* with different molecular weights. The prepared crude and homogeneous polysaccharides of *Mesona chinensis* have good antioxidant capacity and can promote the growth of *Bacteroides* in the gut. In vitro experiments verified that the metabolites of *Mesona chinensis* polysaccharide have good lipid-lowering activity.

The present application discloses a polysaccharide for preventing, treating or improving chronic constipation, and a preparation method and application thereof. The polysaccharide can improve or restore intestinal barrier integrity, increase the expression amount of colon tight junction proteins, regulate the proportion of intestinal microbe beneficial flora, increase the content of short-chain fatty acids, improve gastrointestinal motility, regulate intestinal oxidative stress, increase the fecal water content and intestinal transport rate of constipation subjects, reduce intestinal tissue damage, and the like, thereby being capable of being used for preventing, treating or improving chronic constipation. In addition, the polysaccharide has the advantages of high safety and good curative effect.

The utility model provides a kind of high-efficiency air cooler, including main body, the lower four corners of main body are evenly installed with support foot, the inner wall of main body is installed with two partitions, the inside space of main body is divided into multiple chambers by two partitions, the side of each chamber is communicated and is provided with fan. The utility model is provided with cooling mechanism in the inside of each chamber, i. e. by being provided with guide vane to the wind that enters is guided, so that wind is more concentrated, after cooling and cooling down by cooling pipe, blow to multiple trapezoidal fins, trapezoidal fin can increase the turbulence of air flow, improve heat transfer coefficient;Wavy fin can extend the flow path of air between fin, increase heat exchange time, finally after the heat exchange of heat exchange pipe, greatly improve the heat exchange efficiency, satisfy greater cooling demand, and do not need to add fan and other equipment, reduce energy consumption.

The application discloses a coal-based hard carbon negative material of a sodium ion battery and a preparation method thereof, and the preparation method is as follows: coal powder and starch are uniformly mixed to obtain a coal-based hard carbon precursor; then the precursor is placed in a high-temperature and high-pressure device, the device is heated and pressurized, and the precursor is cross-linked and pre-carbonized, so that the cross-linking degree between the starch and the coal powder is greatly improved; then, the pre-carbonized material after treatment is secondarily crushed, after the crushing is completed, the material is placed in a high-temperature and inert gas atmosphere for carbonization, and finally, the coal-based hard carbon negative material with excellent performance is obtained. The coal-based hard carbon product interlayer distance can be obviously improved, the electrochemical performance of the coal-based hard carbon is improved, and the processing technology is simplified.

The application discloses a silicon-carbon composite material and a preparation method and application thereof, and belongs to the field of electrochemical energy storage. The silicon-carbon composite material comprises a silicon-based active substance and a low-crystallization carbon matrix, the low-crystallization carbon matrix coats and / or disperses the silicon-based active substance; and the Raman spectrum ID / IG value of the low-crystallization carbon matrix is greater than 1.2. The low-crystallization carbon matrix has high disorder degree and toughness, can better adapt to the volume expansion and shrinkage of silicon in the charging and discharging process, maintains the integrity of the electrode structure, and thus significantly improves the cycle stability; the low-crystallization carbon surface contains more defects and functional groups, which is helpful to form a stable and dense SEI film, reduces the side reaction in the cycle process and the irreversible consumption of active lithium.

The invention belongs to the technical field of microbial engineering, and discloses bifidobacterium animalis subsp. Lactis JJKK012 capable of producing exopolysaccharides and application of the bifidobacterium animalis subsp. Lactis JJKK012. The problem that the bifidobacterium animalis subsp. Lactis capable of producing exopolysaccharides at high yield and simultaneously exerting antibacterial and immunoregulation effects is lacked at present is solved. The preservation number of the animal bifidobacterium subsp. Lactis JJKK012 is CGMCC (China General Microbiological Culture Collection Center) No.35555, the viable count of the strain is greater than or equal to 1 * 10 < 11 > CFU / g, and the content of exopolysaccharides reaches 856.5 mg / L. The bifidobacterium animalis subsp. Lactis JJKK012 disclosed by the invention can be used for effectively activating RAW264.7 macrophages and exerting a function of enhancing immunity; meanwhile, the strain has good acid resistance, gastrointestinal fluid tolerance, antibacterial ability and cell adhesion ability, and has the function of regulating intestinal flora.

The invention relates to the technical field of biological medicines, in particular to application of tangeretin in preparation of a medicine for activating an aromatic hydrocarbon receptor pathway. The invention provides application of tangeretin in preparation of a medicine for activating an aromatic hydrocarbon receptor pathway. Specifically, the tangeretin effectively activates an aromatic hydrocarbon receptor pathway by promoting aromatic hydrocarbon receptor nuclear translocation and / or up-regulating expression of downstream target genes. The activated aromatic hydrocarbon receptor pathway further up-regulates the expression of tight junction protein and / or inhibits the expression of proinflammatory factors, thereby achieving the efficacy of improving intestinal barrier injury and / or regulating intestinal flora disorder. Therefore, the tangeretin can be used as a medicine for preventing or treating diseases, disorders or symptoms related to the activity of the aromatic hydrocarbon receptor, and particularly has important application value in the aspects of improving intestinal barrier injury and / or regulating intestinal flora disorder.

The application relates to the field of building materials, and particularly discloses a coal gangue activation treatment method, calcined coal gangue prepared by the method and application, the treatment method comprises the following steps: pretreatment: crushing and screening coal gangue to obtain coal gangue particles; pretreatment: treating the coal gangue particles in a eutectic solvent, and performing ultrasonic auxiliary treatment for 2-3 hours, and obtaining pretreated coal gangue after washing, the eutectic solvent comprises HBA components and HBD components, the HBA components are selected from a mixture of choline chloride and an amide compound, and the HBD components are selected from a mixture of a carboxylic acid compound and a polyhydric alcohol mixture; calcination: calcining the pretreated coal gangue at 400-450 DEG C to obtain calcined coal gangue, and the application further discloses the calcined coal gangue prepared by the method, and the application has the characteristics of realizing coal gangue activation treatment at a lower energy consumption.

This invention belongs to the field of magnetic functional materials technology, specifically relating to an amorphous nanocrystalline ribbon and its preparation method. The amorphous nanocrystalline ribbon is composed of the following raw materials in the indicated mass percentages: Nb 5.6-6.5 wt%, Si 9.5-10.5 wt%, B 1-2 wt%, Cu 0.5-1 wt%, Co 0.1-0.2 wt%, Zr 0.05-0.1 wt%, rare earth elements 0.4-1.5 wt%, high-entropy oxide 0.5-1.0 wt%, with the balance being Fe. The high-entropy oxide is prepared by adding ferric chloride, cobalt chloride, nickel chloride, manganese chloride, and scandium chloride to diethylene glycol, heating and stirring under sealed conditions, followed by centrifugation, washing, drying, and calcination to obtain the high-entropy oxide. The amorphous nanocrystalline ribbon prepared by this invention exhibits high magnetic permeability, low coercivity, and high stability within the temperature range of -40℃ to +150℃.

The invention relates to application of dihydromyricetin in preparation of a medicine for preventing or treating amyotrophic lateral sclerosis. Through specific natural active ingredient selection and pharmacological mechanism integration, dihydromyricetin is used as an active ingredient for preparing the ALS treatment medicine, and the nerve protection effect is achieved by directly utilizing the inherent pharmacological characteristics of dihydromyricetin; dihydromyricetin resists nerve injury induced by neurotoxin BMAA, acts on motor neuron denaturation in a targeting manner, remarkably improves axonal structure injury, effectively blocks oxidative stress mediated nerve injury chain reaction by reducing the content of lipid peroxide and improving the activity of antioxidant enzyme, and meanwhile, effectively inhibits oxidative stress mediated nerve injury chain reaction by reducing the content of lipid peroxide and improving the activity of antioxidant enzyme. By means of multi-dimensional regulation and control of a neurotransmitter system and ALS related genes, systematic neuroprotection from morphology and biochemical indexes to the molecular level is achieved.