10 results about "Dipicolinic acid" patented technology

The invention discloses a preparation method of a dipicolinic acid anhydride solution, which comprises the following steps: 1, adding acetic anhydride into a reaction kettle, heating, adding dipicolinic acid, mixing, and further heating for reaction; 2, after the reaction is finished, acetic anhydride and acetic acid are recycled in a distillation mode; and 3, the reaction liquid without acetic anhydride and acetic acid is subjected to vacuum rectification, the obtained fraction flows into a receiving kettle in a gaseous state during rectification, the receiving kettle is filled with a solvent capable of dissolving dipicolinic acid anhydride, the mass of the distilled material is determined through a weighing method, and the mass fraction of the product in the solution is 10-15%. The method has the advantages that the process route is simple, the steps are few, the acetic anhydride is convenient and environment-friendly to reuse, the production cost is effectively reduced, and the product purity is high and can reach 99% or above. And the solution is low in water content and more convenient to use, and meets the requirements of additives of lithium ion battery electrolytes.

A water-soluble automatic dishwashing detergent pouch includes an automatic dishwashing detergent composition that is enclosed by a water-soluble film. The automatic dishwashing detergent composition includes dipicolinic acid and / or salt thereof; and from above about 0 g to less than about 8.0 g silicate salt, with the level of silicate salt being less than about 3.0 wt. % of the automatic dishwashing detergent composition. The weight ratio of dipicolinic acid and / or salt thereof to silicate salt is greater than about 5:1.

Methods for selecting a microbe for co-formulation with a carrier are provided. In some examples, the methods include identifying a microbe that comprises one or more dipicolinic acid (DPA) synthase genes, a microbe that expresses one or more DPA synthase proteins, and / or a microbe that produces DPA; and selecting the microbe for co-formulation with a carrier. The methods optionally include co-formulating the selected microbe with the carrier. In some examples, the methods include detecting one or more DPA synthase genes or one or more DpaA and / or DpaB proteins in a microbe. In other examples, the methods include detecting DPA in a microbe or medium containing a microbe, for example, utilizing a fluorescence assay. Microbial compositions including one or more microbes that comprise one or more DPA synthase genes, express one or more DPA synthase proteins and / or produce DPA are also provided.

A water-soluble automatic dishwashing detergent pouch that contains the combination of dipicolinic acid and / or salt thereof together with polyaspartate.

The invention discloses a construction method, a construction structure and application of a picolinic acid electrochemical sensor based on an intramolecular DNA nano machine. The construction method comprises the following steps: preparing an X-type DNA nano structure, constructing a sandwich composite probe SSC, constructing an electrochemical sensing interface for detecting picolinic acid, and quantitatively detecting picolinic acid in a bacterial sample. According to the electrochemical sensor for detecting the dipicolinic acid, the reaction probe is immobilized by using an X-type nano bracket XSP, an intramolecular DNA nano machine is constructed, efficient signal output is performed through catalytic oxidation reduction cycle amplification, sensitive detection of the dipicolinic acid released by bacterial spores is realized, and the detection limit is as low as 7.4 pM. The research has important application value in the aspects of prevention, diagnosis and treatment of diseases such as anthrax.

The invention relates to the technical field of material analysis, relates to a low-temperature separation and sampling process for metal elements in a fluorine-containing polymer, and aims to solve the problem that the metal elements in fluorine-containing polymer particles are difficult to fully digest and avoid loss and interference during separation and sampling. The low-temperature separation and sampling process for the metal elements in the fluorine-containing polymer comprises the following steps: putting a fluorine-containing polymer sample, a grinding ball and a digestion solution into a digestion tank, and sealing; starting a ball milling digestion program; after the reaction is finished, filtering the reaction liquid, and fixing the volume to obtain a to-be-measured liquid for measuring the content of the metal elements; the digestion solution comprises a main digestion solution and an additive, and the main digestion solution comprises nitric acid and hydrogen peroxide; the additive comprises ammonium nitrate, dipicolinic acid and boric acid. According to the low-temperature separation and sampling process for the metal elements in the fluorine-containing polymer, provided by the invention, on the basis of the synergistic effect of mechanical ball milling and chemical digestion, fluorine-containing polymer particles can be fully digested at a relatively low temperature, and meanwhile, impurities can be prevented from being introduced under the closed condition of the digestion tank.

The invention belongs to the technical field of immunoassay and biosensing, and provides a preparation method and application of an electrochemiluminescence sensor based on a self-luminous europium-based metal organic framework. A europium-based metal organic framework is adopted as an electrogenerated chemiluminescence material, and an organic ligand 2, 6-dipicolinic acid utilizes an antenna effect to improve an intramolecular energy transfer path, so that europium ions are efficiently sensitized, and a high-strength electrogenerated chemiluminescence signal is obtained. Nitrogen-doped carbon-coated copper-cobalt alloy balls are adopted as a co-reaction accelerant, on one hand, a high-conductivity nitrogen-doped carbon layer can improve the migration rate of charges, on the other hand, a copper-cobalt bimetallic catalyst active center can promote generation of more strong-oxidizing-property triethylamine free radicals, and the luminous efficiency of the europium-based covalent organic framework is further improved. A layer-by-layer self-assembly technology is utilized to construct a signal enhanced electrochemiluminescence sensor, and sensitive and rapid detection of carbohydrate antigen 724 is realized.

The present invention relates to a water-soluble automatic dishwashing detergent pouch that contains the combination of dipicolinic acid and / or salt thereof together with sulphonated carboxylate polymer.

The invention discloses a preparation method and application of a Ni-Eu-DPA three-dimensional coordination framework crystal material, and relates to a preparation method and application of a three-dimensional coordination framework crystal material. The problems that in the existing aromatic ketone alpha-H deuteration field, the photocatalytic light excitation state service life is short, the energy utilization rate is low, the reaction selectivity needs to be improved, the deuterium source is expensive, and the conditions are harsh are solved. The preparation method comprises the following steps: 1, dissolving Ni (ClO4) 2.6 H2O in water, then adding dipicolinic acid, heating and stirring to obtain a system A; 2, Eu (NO3) 3.6 H2O is dissolved in water, then picolinic acid is added, heating and stirring are conducted, and a system B is obtained; and 3, mixing the system A and the system B, transferring the mixture into a polytetrafluoroethylene reaction kettle for solvothermal reaction, and naturally cooling to room temperature to separate out light green flaky crystals. The photocatalyst is applied to the selective deuteration reaction of aromatic ketone alpha-H.

The present invention discloses a tetraazacyclic Tb(III) complex containing a triphenylamine fluorophore, a synthesis method thereof and applications thereof, belonging to the field of biomedicine. In the present invention, triphenylamine is used as an energy donor, which is connected to a tetraazacyclic ring with three amide arms through an amide bond to obtain a ligand TPA-Cy, and the ligand reacts with Tb<supgt;3+< / supgt; to obtain a tetraazacyclic Tb(III) complex containing a triphenylamine fluorophore, namely TPA-Cy-Tb. This complex can enhance fluorescence in aqueous solution to respond and recognize the biomarker dipicolinic acid of anthrax spores, and the lowest detection limit reaches 72 nM. The prepared TPA-Cy-Tb can be used to prepare a fluorescence probe for the quantitative detection of anthrax spores in the environment. The present invention has the advantages of cheap synthesis raw materials, simple synthesis process, easy separation procedure, high yield, stability and easy preservation. The fluorescence probe of the complex of the present invention can specifically be activated by DPA to have a fluorescence response and is used for the quantitative detection of anthrax spores, and has excellent biological application prospects.