This invention relates to a synthesis method of acetylation di-starch adipate, which takes starch, acetic anhydride, hydrochloric acid, sodium hydroxide, adipic acid as raw materials in water medium, and conducts eight steps of preparing chemicals, conditioning, alkalization, neutralization, washing, drying, screening, and packaging to obtain the product, which has white powder particles, DS of 0.01~0.07, 6% paste E point viscosity of 500 ~ 3000BU. Compared with similar product on the market, the invention has good viscosity, transparency, replacement, shear resistant, heat resistant, and the produced food has good water storage, absorbent, expansion, so it is suitable for sauces and leisure food.