351 results about "Antimicrobial" patented technology

The present disclosure relates generally to antimicrobial gels. In particular, the present disclosure relates to an antimicrobial gel comprising a eutectic solvent and a gelling agent which can be used as a drug delivery vehicle for antimicrobial agents, including for the topical delivery of antimicrobial agents to the skin of a subject. The present disclosure also relates to processes for preparing the antimicrobial gel, and to methods, uses and compositions comprising the antimicrobial gel.

A composition having an additive or component having an antimicrobial or a preservative property, and 3-phenylpropanol or a member of the phenylpropanoid family is provided. A composition having a polymer, an organic acid, and 3-phenylpropanol or a member of the phenylpropanoid family is provided as well as a method(s) of using.

An image forming apparatus includes: a forming unit configured to form an image on a sheet by forming a plurality of toner images using a plurality of types of toner, and transfer the plurality of toner images onto the sheet, or transfer the plurality of toner images onto the sheet via an intermediate transfer member; and a controller configured to control the forming unit to form a formed image and an antimicrobial pattern on the sheet based on first image data representing the formed image, wherein at least one first toner out of the plurality of types of toner is antimicrobial toner that includes an antimicrobial agent, at least one second toner out of the plurality of types of toner is non-antimicrobial toner that does not contain the antimicrobial agent, and the antimicrobial pattern is formed using the first toner.

The invention relates to the technical field of coatings, and discloses a UV-curable water-based coating and a preparation method thereof. The UV-cured water-based paint is prepared by taking water-based polyurethane acrylate emulsion and water-based epoxy modified acrylic resin as main raw materials, adding functional aids such as a modified antibacterial agent, an inorganic filler, a photoinitiator and a silane coupling agent, and mixing. Wherein the modified antibacterial agent utilizes the synergistic effect among a benzoxazine structure, a quaternary ammonium salt structure, a thiazole structure and a carbon-carbon double bond to endow the coating with excellent antibacterial performance, so that the application field of the coating is widened, and the coating has certain application prospects in the aspects of wooden furniture, plastic products, printing and packaging and the like.

Novel compositions are described, each comprising at least one active constituent that has a 12-carbon atom backbone as a 12-carbon chain base structure having at least a sub-terminal nitrogen and no terminal amino group. One of the active constituents is Boc-12-Ado-OH (BOA) and / or N,N-dimethyldodecylamine N-oxide (LO). Novel particle or liposomal compositions comprising at least BOA and / or LO may be prepared with an emulsifier and / or lipid and optionally a biopolymer, and may be formulated into pharmaceutically acceptable formulations and / or medicaments with or without one or more pharmaceutically acceptable carriers or excipients for utilization as an antimicrobial against one or more microbial pathogens. The novel antimicrobial compositions have broad-spectrum growth inhibitory or other destructive activity against microbial pathogens, biofilms produced by one or more pathogens, and biofilm infections.

Feed additives including Chlamydomonas reinhardtii and a medium-chain fatty acid provide reduced risk of bacterial infection in animals. The feed additives are administered to animals in feed compositions.

The invention belongs to the technical field of polyurethane elastomers, and particularly relates to a modified polyester polyol, an antibacterial polyurethane microporous elastomer and a preparation method of the elastomer. The modified polyester polyol is prepared by adopting graft modification Ag (at) SiO2, and the antibacterial polyurethane microporous elastomer is prepared from the modified polyester polyol. The antibacterial polyurethane microporous elastomer is mainly prepared by mixing and curing a component A and a component B, the component A mainly comprises conventional polyester polyol and modified polyester polyol, and the component B mainly comprises conventional polyester polyol, polyether polyol and isocyanate; according to the antibacterial polyurethane microporous elastomer and the preparation method thereof provided by the invention, the prepared polyurethane microporous elastomer is long-acting and stable in antibacterial performance and uniform in dispersion, and keeps excellent physical and mechanical properties and a microporous structure at the same time.

The present invention relates to an antimicrobial oligomer and to an antimicrobial coating composition comprising said antimicrobial oligomer. The present invention also relates to a medical device comprising the antimicrobial coating composition and to a method for coating said coating composition on a medical device.

A composition is provided that includes hydrolyzed collagen, at least one biguanide, at least one vicinal diol, and at least one chelating agent. The composition exhibits at least 2-log reduction of planktonic microbes within 24 hours. Methods of using the composition are also provided.

To provide a detection method capable of rapidly detecting drug-resistant bacteria, bacteria of the genus Staphylococcus, and bacteria of the genus Pseudomonas; a method for providing an index for selecting an antimicrobial agent for bacteria; and a primer set usable in these methods.SOLUTION: The detection method for drug-resistant bacteria, bacteria of the genus Staphylococcus, and bacteria of the genus Pseudomonas according to the present disclosure comprises a step of performing nucleic acid amplification of target genes (1) to (3) and (4) below for a target sample, and detecting drug-resistant bacteria, bacteria of the genus Staphylococcus, and bacteria of the genus Pseudomonas in the sample: (1) the mecA gene; (2) the spa gene of Staphylococcus aureus; (3) the tuf gene and / or the rpoB gene of bacteria of the genus Staphylococcus; and (4) the 16S rRNA gene of bacteria of the genus Pseudomonas.SELECTED DRAWING: Figure 1

A spinal implant includes a base and a coating film disposed on the base and including a calcium phosphate-based material and an antimicrobial agent. A surface of the base includes a first region in which the coating film is disposed and a second region exposed from the coating film.

The present invention pertains to use of sodium diacetate (NaHAC2) as an antimicrobial agent against bacteria growing in biofilms. The aspects of the invention include a wound care product comprising sodium diacetate, a kit comprising a wound care product, and a method of treating an infected wound.

A novel active agent-eluting hemostatic agent and methods of use and manufacture thereof are presented. A polymer, such as gelatin, is used as the base for a hemostatic agent. The gelatin is crosslinked with a chemical crosslinker, such as a carbodiimide, in the presence of an active agent. The active agent may be an anesthetic or antimicrobial, such as an antibiotic. The novel process allows for the active agent to be both covalently bound to the gelatin as well as be trapped within cages in the gelatin that are formed from the crosslinking. This dual measure allows for controlled and sustained release of the active agent from the hemostatic agent to reduce surgical site infections.

A dynamic antimicrobial hydrogel based on natural receptor-ligand recognition, and a preparation method and use thereof are provided. A ligand vancomycin and a receptor AA-based material each are first modified with a modification material, and then a photoinitiator is added to prepare a hydrogel material under irradiation of ultraviolet (UV) light. In the hydrogel, a three-dimensional (3D) network structure is formed through crosslinking. After undergoing a fracture under an external pressure, the hydrogel can rapidly heal itself through crosslinking due to a ligand-receptor interaction and a multi-hydrogen-bond interaction, which bio-mimicks a natural ligand-receptor interaction to realize the dynamics of the hydrogel material. The high antiomicrobial activity of vancomycin imparts the functionality of the hydrogel material; and the physiologically-derived monomer improves the biocompatibility and reduces the biological toxicity.

The microorganism strain Pediococcus acidilactici TAK 589 CoccobEst is a new antimicrobial and antioxidant probiotic, CoccobEst inhibits the growth of the enteropathogens L. monocytogenes, E. coli, S. enteritidis, S. typhimurium, S. sonnei, S. aureus, E. faecalis and C. sakazakii, but does not inhibit lactobacilli of natural intestinal microbiota. The strain's antimicrobial properties are enhanced by periplasmic peptidoglycan hydrolases with proteolytic activity. CoccobEst is used as a zootechnieai feed additive to prevent bacterial infections in the gastrointestinal tract of farm animals and pets and to prevent and reduce diarrhea. CoccobEst has highly active antioxidant defense system, increasing the redox activity of glutathione and reducing oxidative stress in cells. Therefore, CoccobEst is used as a food supplement or functional food for humans to prevent bacterial infections of the gastrointestinal tract and to prevent and reduce oxidative stress. In addition, CoccobEst is used as a starter culture in fermentation of vegetables.

The invention relates to a bicycle or scooter helmet (2), notable in that it consists of a shock-absorbing layer (2a) of expanded polypropylene (EPP) that is waterproof and monolithic, the surface of the monolithic helmet (2) is self-cleaning, and the composition of the expanded polypropylene includes antimicrobial agents, such as silver ions or ceramic microspheres, and the internal surface of the helmet (2) is continuous, without any recessed or raised elements. Figure for the abstract: Fig. 9

Provided in the present invention are an antimicrobial whitening composition, a white synthetic leather substrate and a preparation method therefor, and an antimicrobial synthetic leather. The antimicrobial whitening composition comprises a cationic antimicrobial agent, an antimicrobial organic substance and a solvent, wherein the cationic antimicrobial agent comprises at least one of a polymeric quaternary ammonium compound, polyethyleneimine, chitosan, a biguanide compound and a polymeric biguanide; and the antimicrobial organic substance comprises at least one of a terpene compound and a derivative thereof, a phenolic compound, an essential oil, an antifungal agent, a preservative and a disinfectant. The man-made leather prepared by means of the antimicrobial whitening composition of the present invention has good performance in terms of both long-lasting antimicrobial properties and maintaining a high whiteness.

The present disclosure provides a delivery system 1 comprising a fibrous substrate 10 with continuous pores 13 and a composition homogenously bonded to the pores 13. The fibrous substrate 10 comprises at least a predetermined percentage of cotton and one or more materials selected from the group of consisting spandex, nylon, silver and antimicrobial mesh. The composition comprises a predetermined percentage of beeswax and a predetermined percentage of mineral oil. The predetermined percentage of beeswax is greater than the predetermined percentage of mineral oil.

The invention relates to a pyruvate kinase-targeted compound shown as a formula I, a preparation method and application thereof, and application of the pyruvate kinase-targeted compound serving as a plant antibacterial agent, and part of the pyruvate kinase-targeted compound shows excellent bactericidal activity.

A disinfection tip is described for disinfecting a threaded connector of a syringe. The disinfection tip includes a cylindrical outer housing, a substantially cylindrical inner housing extending from a distal wall of the outer housing, a distal chamber defined by the outer sidewall of the inner housing, the inner wall of the outer housing and the distal wall of the outer housing, the distal chamber being in fluid communication with the cavity, the distal chamber retaining a disinfectant or antimicrobial agent when the disinfection tip is disposed within an outer wall of the luer connector of the syringe and, at least one jet orifice radially disposed on the inner rim in fluid communication with the distal chamber allowing for fluid to pass from the distal chamber through the jet orifice directing the disinfectant or antimicrobial agent towards a center of the outer housing when the disinfection tip is further inserted into the luer connector of the syringe, the insertion of the disinfection tip causing the volume of the distal chamber to reduce and expel disinfectant or antimicrobial agent through the at least one jet orifice.

A general formula for lysins based on which the activity and functionality are further screened and 24 lysins are identified and further investigated, nine of which are characterized. These lysins exhibit potent bactericidal activity, capable of lysing multiple species of Staphylococcus, Streptococcus, and / or Enterococcus; demonstrate robust environmental resistance and stability, retaining activity under varying temperatures, NaCl concentrations, pH levels, and in immune serum; and effectively treat localized and systemic infections. These lysins and their variants are promising as antimicrobial agents for eradicating bacteria, preventing bacterial infections, or treating bacterial infections (caused by genera Staphylococcus, Streptococcus, and / or Enterococcus).

The invention relates to a medical treatment unit, in particular a dental treatment unit, comprising a water leading system and a measurement unit for the quantitative measurement of an antimicrobial agent content in water contained in the water leading system.

Peptides for use in systems that prevent the interaction of the FadA protein released from the Fusobacterium nucleatum (F. nucleatum) bacterium with E-cadherin, which has a carcinogenic effect, or the inhibition of the microorganism with antimicrobial agents and that will inhibit the carcinogenesis mechanisms of F. nucleatum infection and enable the development of therapeutic systems against infections that may occur due to the decreased immunity of patients undergoing cancer treatment with the use of peptides with anti-cancer and antimicrobial properties by developing ten peptides with FadA protein binding energy greater than −11.6 kcal / mol. Peptides with anticancer and antimicrobial properties allow the development of therapeutic systems to prevent F. nucleatum infection, to prevent cancer development after F. nucleatum infection, or to develop therapeutic systems against infections that occur due to the decreased immunity of cancer patients due to cancer treatment.

The present invention relates to an antimicrobial coating composition comprising, based on the total weight of the coating composition, 30-60% by weight of a polyester resin, 3-15% by weight of a curing agent, 0.1-5% by weight of an antimicrobial agent, 0.1-15% by weight of a pigment, and the balance being a solvent. The present invention further relates to an antimicrobial coated steel sheet comprising a steel sheet and an antimicrobial coating layer formed on at least one surface of the steel sheet, the antimicrobial coating layer containing an antimicrobial agent in at least a part thereof, the antimicrobial agent having a content ratio Z / (M+Ca) of 0.1-0.5, M being Ca, Ba, Mg, Zn, Ni, Fe or Al, and Z being P, As, V or Si. The antimicrobial coating composition according to the present invention contains an antimicrobial agent. When the composition forms a coating layer, the antimicrobial agent is concentrated on the surface of the coating layer, so that microorganisms adsorbed on the surface of the coating film together with moisture are effectively killed by hydroxyl radical species and hydroxide anions generated on the surface of the coating film. Thus, a coated steel sheet using the antimicrobial coating composition according to the present invention has excellent design properties as well as excellent processability, chemical resistance, etc.

A polypeptide corresponding to the amino acid sequence SEQ ID No 1, wherein said polypeptide has antimicrobial activity; An antimicrobial composition, comprising said polypeptide, and optionally a second antimicrobial agent and a carrier; Use of the antimicrobial composition to inhibit the growth and proliferation of Gram-positive and Gram-negative bacteria.

A solid material including a matrix, dispersed in which are microparticles of at least one antimicrobial agent for preventing, limiting and / or eliminating the contamination of the material and / or the contamination of a composition which is in contact with the material for at least a given time, and / or preventing, eliminating and / or slowing down the formation of biofilms on the surface of the material, wherein the antimicrobial agent is an oxide of at least one positively charged metal ion and the antimicrobial agent does not migrate out of the material. Also, the use of such material for manufacturing an article, to the process for manufacturing the article, and to the article obtained. In particular, the article is selected from stoppers, lids, seals, caps, covers, plugs and valves intended for sealing bottles, flasks, jars, cans, canisters, barrels, tanks, or various containers used for packaging and / or storing food products, dietetic products, cosmetic products, dermatological products or pharmaceutical products.

Provided herein are hydrogels that include a plurality of amine-containing antimicrobial agents within the interiors of the hydrogels. The antimicrobial agents are connected to the hydrogel interiors via dynamic covalent imine bonds, and the hydrogel is engineered to facilitate controlled release of the antimicrobial agents. Also provided are methods for forming the provided hydrogels, and for using the hydrogels to treat a subject suffering from a microbial infection.

In some aspects, disclosed herein are compounds of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions thereof. In some aspects, the compounds and compositions provided herein may be used to modulate the activity of Staphylococcus aureus. Also provided are methods of administering compounds and composition provided herein to a patient in need thereof, for example, for the treatment or prevention of diseases or disorders.

A universal cap for connection to a medical connector facilitates easier alignment and engagement of the cap with a threaded male or female Luer medical connector and enhances connector disinfection. A split collar projection projects axially from the closed end wall of the cap toward the open bottom and includes at least one pair of opposed parallel fan-shaped chuck fingers / forks terminating at a projection end. The inner wall of each chuck finger defines a split flange cantilever, respectively. The inner wall and the outer wall of each collet finger define a split thread, each of which is dimensioned to mate with a respective corresponding thread mating of a Luer connector. An antibacterial agent infused absorbent material is oriented between the split flange and the cap bottom. When the cap is attached to the Luer connector, the absorbent material compresses the offset split flange and deflects the collet finger / fork to more easily align and engage the cap with the Luer medical connector and enhance connector disinfection.