483 results about "Antimicrobial" patented technology

The present disclosure relates generally to antimicrobial gels. In particular, the present disclosure relates to an antimicrobial gel comprising a eutectic solvent and a gelling agent which can be used as a drug delivery vehicle for antimicrobial agents, including for the topical delivery of antimicrobial agents to the skin of a subject. The present disclosure also relates to processes for preparing the antimicrobial gel, and to methods, uses and compositions comprising the antimicrobial gel.

A device includes a central body having an array of scrubbing features that extend away from a first surface of the central body. The array of scrubbing features is arranged in wave-shaped pathways extending radially from a first end of the pathways at an interior of the central body toward a second end of the pathways at a periphery of the central body. The array of scrubbing features includes a first set of scrubbing features extending a first height away from the first surface and a second set of scrubbing features extending a second height away from the first surface. The device has a unitary structure made of silicone and infused with an antimicrobial agent. The device is configured to be more durable and have a longer use time than conventional bath and shower devices thereby mitigating climate change.

A composition having an additive or component having an antimicrobial or a preservative property, and 3-phenylpropanol or a member of the phenylpropanoid family is provided. A composition having a polymer, an organic acid, and 3-phenylpropanol or a member of the phenylpropanoid family is provided as well as a method(s) of using.

A device includes a central body having an array of scrubbing features that extend away from a first surface of the central body. The array of scrubbing features is arranged in wave-shaped pathways extending radially from a first end of the pathways at an interior of the central body toward a second end of the pathways at a periphery of the central body. The array of scrubbing features includes a first set of scrubbing features extending a first height away from the first surface and a second set of scrubbing features extending a second height away from the first surface. The device has a unitary structure made of silicone and infused with an antimicrobial agent. The device is configured to be more durable and have a longer use time than conventional bath and shower devices thereby mitigating climate change.

The invention refers to an antimicrobial, exfoliating and seboregulating hydrosoluble composition comprising a combination of diallyl disulphide modified oxide (DDMO) and alpha hydroxyethanoic acid (glycolic acid), which acts removing bacteria affecting the skin including those caused by acne, said composition also provides deep cleansing, exfoliating action, reduces epidermal cohesion facilitating cellular change, preventing the occurrence of several forms of acne in the skin and additionally producing seboregulating effects by avoiding blockage of sebaceous glands.

A composition having an additive or component having an antimicrobial or a preservative property, and 3-phenylpropanol or a member of the phenylpropanoid family is provided. A composition having a polymer, an organic acid, and 3-phenylpropanol or a member of the phenylpropanoid family is provided as well as a method(s) of using.

In one aspect, nutraceutical compositions, methods of preparation and methods of use comprise a nutraceutical composition comprising an antimicrobial hevamine A-related protein from Momordica balsamina alone or in combination with one or more nutraceutical ingredients. In another aspect, a method of preventing or treating a microbial infection in a plant comprises applying an effective amount of a composition containing the hevamine A-related protein to a whole plant, plant part, or media in which the plant is growing. In a further aspect, the present application provides a transgenic plant stably transformed with a polynucleotide encoding the hevamine A-related protein.

Provided are compositions and methods for selectively reducing the amount of antibiotic resistant and / or virulent bacteria in a mixed bacteria population, or for reducing any other type of unwanted bacteria in a mixed bacteria population. The compositions and methods involve targeting bacteria that are differentiated from other members of the population by at least one unique clustered regularly interspaced short palindromic repeats (CRISPR) targeted DNA sequence. The compositions and methods can be readily adapted to target any bacteria or any bacteria plasmid, or both.

An image forming apparatus includes: a forming unit configured to form an image on a sheet by forming a plurality of toner images using a plurality of types of toner, and transfer the plurality of toner images onto the sheet, or transfer the plurality of toner images onto the sheet via an intermediate transfer member; and a controller configured to control the forming unit to form a formed image and an antimicrobial pattern on the sheet based on first image data representing the formed image, wherein at least one first toner out of the plurality of types of toner is antimicrobial toner that includes an antimicrobial agent, at least one second toner out of the plurality of types of toner is non-antimicrobial toner that does not contain the antimicrobial agent, and the antimicrobial pattern is formed using the first toner.

The present disclosure provides a delivery system comprising a fibrous substrate with continuous pores and a composition homogenously bonded to the pores. The fibrous substrate comprises at least a predetermined percentage of cotton and one or more materials selected from the group of consisting spandex, nylon, silver and antimicrobial mesh. The composition comprises a predetermined percentage of beeswax and a predetermined percentage of mineral oil. The predetermined percentage of beeswax is greater than the predetermined percentage of mineral oil.

A device includes a central body having an array of scrubbing features that extend away from a first surface of the central body. The array of scrubbing features is arranged in wave-shaped pathways extending radially from a first end of the pathways at an interior of the central body toward a second end of the pathways at a periphery of the central body. The array of scrubbing features includes a first set of scrubbing features extending a first height away from the first surface and a second set of scrubbing features extending a second height away from the first surface. The device has a unitary structure made of silicone and infused with an antimicrobial agent. The device is configured to be more durable and have a longer use time than conventional bath and shower devices thereby mitigating climate change.

The invention relates to the technical field of coatings, and discloses a UV-curable water-based coating and a preparation method thereof. The UV-cured water-based paint is prepared by taking water-based polyurethane acrylate emulsion and water-based epoxy modified acrylic resin as main raw materials, adding functional aids such as a modified antibacterial agent, an inorganic filler, a photoinitiator and a silane coupling agent, and mixing. Wherein the modified antibacterial agent utilizes the synergistic effect among a benzoxazine structure, a quaternary ammonium salt structure, a thiazole structure and a carbon-carbon double bond to endow the coating with excellent antibacterial performance, so that the application field of the coating is widened, and the coating has certain application prospects in the aspects of wooden furniture, plastic products, printing and packaging and the like.

A securement device for an infant including a lower layer having a silicone adhesive and a center opening configured to receive an umbilical cord of the infant. An upwardly extending first securement tab and an upwardly extending second securement tab are positioned on opposing sides of the center opening. The first securement tab and the second securement tab define a bridge capturing an umbilical line. The lower layer includes a first antimicrobial, and the first securement tab includes a second antimicrobial.

Provided are compositions and methods for selectively reducing the amount of antibiotic resistant and / or virulent bacteria in a mixed bacteria population, or for reducing any other type of unwanted bacteria in a mixed bacteria population. The compositions and methods involve targeting bacteria that are differentiated from other members of the population by at least one unique clustered regularly interspaced short palindromic repeats (CRISPR) targeted DNA sequence. The compositions and methods can be readily adapted to target any bacteria or any bacteria plasmid, or both.

A method of decellularization of animal tissue, comprising the steps of: mechanical homogenization of animal-derived tissue, incubation of the homogenized tissue from step a) in a solution of trypsin and EDTA, subjecting the filtered tissue to incubation in a PBS buffer solution with a pH in the range of 7.2-7.6 containing a non-ionic detergent at a concentration of 4 - 2% and NH4OH at a concentration of 0.2 - 0.08%, rinsing the tissue with a PBS buffer solution containing an antimicrobial agent, incubation in a deoxyribonuclease solution at a concentration of 0.001 to 0.003% (w / v), rinsing the decellularized tissues obtained with a PBS buffer solution containing an antimicrobial agent, wherein the non-ionic detergent is a compound with a molecular weight of 596 g / mol and additional steps of incubating the tissue in the solution PBS buffer with a pH of 7.2- 7.6 containing a non-ionic detergent at a concentration of 1.5-0.5% and NH4OH ata concentration of 0.2-0.08%, where the incubation is carried out at a temperature below room temperature for 36-48h, and incubation of the tissue in a PBS buffer solution with a pH of 7.2-7.6 containing a non- ionic detergent at a concentration of 0.75-0.25% and NH4OH at a concentration of 0.2-0.08%, where the incubation is carried out at a temperature below room temperature for 36-48h. Bioink containing decellularized tissue of animal origin.

Provided herein are phenazine degrading agents, methods and systems for interfering with viability of bacteria and related antimicrobial and compositions.

The present disclosure generally concerns antimicrobial natural compositions that are based on combinations of extracts, e.g. plant extracts. More specifically, the present disclosure provides antimicrobial compositions comprising at least one saponin extract, an extract from at least one plant species selected from the genus Styrax (a Styrax extract), the genus Myroxylon (a Miroxylon extract), the genus Myrocarpus (a Myrocarpus extract) and mixtures thereof, and at least one additional plant extract from an additional plant source, the saponin extract being from a saponin source different from said plant species of the genera Styrax, Myroxylon, or Myrocarpus, and from said additional plant source.

Described herein are systems, methods, and devices for antimicrobial susceptibility testing (AST) directly from blood samples. A system for enriching samples includes a housing configured to receive sample containers, sample preparation cartridges, and AST cartridges, for processing and testing samples using one or more centrifuges, pipetting systems, a controller, AST subsystem, magnet station, microscope, and heater disposed inside the housing. The system is configured to transfer a sample from a blood sample container into a processing tube in a sample preparation cartridge using a septum and needle-based pipetting system. Upon transfer of the sample, the system performs steps to separate, enrich, and concentrate pathogens in the sample for rapid detection. The system then dispenses aliquots of the enriched sample into antimicrobial-containing reaction wells in an AST cartridge, acquires images of each reaction well after incubation, and determines pathogen susceptibility to antimicrobials based on analyzing the acquired images.

Provided are compositions and methods for selectively reducing the amount of antibiotic resistant and / or virulent bacteria in a mixed bacteria population, or for reducing any other type of unwanted bacteria in a mixed bacteria population. The compositions and methods involve targeting bacteria that are differentiated from other members of the population by at least one unique clustered regularly interspaced short palindromic repeats (CRISPR) targeted DNA sequence. The compositions and methods can be readily adapted to target any bacteria or any bacteria plasmid, or both.

Provided are compositions and methods for selectively reducing the amount of antibiotic resistant and / or virulent bacteria in a mixed bacteria population, or for reducing any other type of unwanted bacteria in a mixed bacteria population. The compositions and methods involve targeting bacteria that are differentiated from other members of the population by at least one unique clustered regularly interspaced short palindromic repeats (CRISPR) targeted DNA sequence. The compositions and methods can be readily adapted to target any bacteria or any bacteria plasmid, or both.

Novel compositions are described, each comprising at least one active constituent that has a 12-carbon atom backbone as a 12-carbon chain base structure having at least a sub-terminal nitrogen and no terminal amino group. One of the active constituents is Boc-12-Ado-OH (BOA) and / or N,N-dimethyldodecylamine N-oxide (LO). Novel particle or liposomal compositions comprising at least BOA and / or LO may be prepared with an emulsifier and / or lipid and optionally a biopolymer, and may be formulated into pharmaceutically acceptable formulations and / or medicaments with or without one or more pharmaceutically acceptable carriers or excipients for utilization as an antimicrobial against one or more microbial pathogens. The novel antimicrobial compositions have broad-spectrum growth inhibitory or other destructive activity against microbial pathogens, biofilms produced by one or more pathogens, and biofilm infections.

Feed additives including Chlamydomonas reinhardtii and a medium-chain fatty acid provide reduced risk of bacterial infection in animals. The feed additives are administered to animals in feed compositions.

The invention belongs to the technical field of polyurethane elastomers, and particularly relates to a modified polyester polyol, an antibacterial polyurethane microporous elastomer and a preparation method of the elastomer. The modified polyester polyol is prepared by adopting graft modification Ag (at) SiO2, and the antibacterial polyurethane microporous elastomer is prepared from the modified polyester polyol. The antibacterial polyurethane microporous elastomer is mainly prepared by mixing and curing a component A and a component B, the component A mainly comprises conventional polyester polyol and modified polyester polyol, and the component B mainly comprises conventional polyester polyol, polyether polyol and isocyanate; according to the antibacterial polyurethane microporous elastomer and the preparation method thereof provided by the invention, the prepared polyurethane microporous elastomer is long-acting and stable in antibacterial performance and uniform in dispersion, and keeps excellent physical and mechanical properties and a microporous structure at the same time.

The present invention relates to an antimicrobial oligomer and to an antimicrobial coating composition comprising said antimicrobial oligomer. The present invention also relates to a medical device comprising the antimicrobial coating composition and to a method for coating said coating composition on a medical device.

A composition is provided that includes hydrolyzed collagen, at least one biguanide, at least one vicinal diol, and at least one chelating agent. The composition exhibits at least 2-log reduction of planktonic microbes within 24 hours. Methods of using the composition are also provided.

To provide a detection method capable of rapidly detecting drug-resistant bacteria, bacteria of the genus Staphylococcus, and bacteria of the genus Pseudomonas; a method for providing an index for selecting an antimicrobial agent for bacteria; and a primer set usable in these methods.SOLUTION: The detection method for drug-resistant bacteria, bacteria of the genus Staphylococcus, and bacteria of the genus Pseudomonas according to the present disclosure comprises a step of performing nucleic acid amplification of target genes (1) to (3) and (4) below for a target sample, and detecting drug-resistant bacteria, bacteria of the genus Staphylococcus, and bacteria of the genus Pseudomonas in the sample: (1) the mecA gene; (2) the spa gene of Staphylococcus aureus; (3) the tuf gene and / or the rpoB gene of bacteria of the genus Staphylococcus; and (4) the 16S rRNA gene of bacteria of the genus Pseudomonas.SELECTED DRAWING: Figure 1

A spinal implant includes a base and a coating film disposed on the base and including a calcium phosphate-based material and an antimicrobial agent. A surface of the base includes a first region in which the coating film is disposed and a second region exposed from the coating film.

The present invention pertains to use of sodium diacetate (NaHAC2) as an antimicrobial agent against bacteria growing in biofilms. The aspects of the invention include a wound care product comprising sodium diacetate, a kit comprising a wound care product, and a method of treating an infected wound.

A novel active agent-eluting hemostatic agent and methods of use and manufacture thereof are presented. A polymer, such as gelatin, is used as the base for a hemostatic agent. The gelatin is crosslinked with a chemical crosslinker, such as a carbodiimide, in the presence of an active agent. The active agent may be an anesthetic or antimicrobial, such as an antibiotic. The novel process allows for the active agent to be both covalently bound to the gelatin as well as be trapped within cages in the gelatin that are formed from the crosslinking. This dual measure allows for controlled and sustained release of the active agent from the hemostatic agent to reduce surgical site infections.

A dynamic antimicrobial hydrogel based on natural receptor-ligand recognition, and a preparation method and use thereof are provided. A ligand vancomycin and a receptor AA-based material each are first modified with a modification material, and then a photoinitiator is added to prepare a hydrogel material under irradiation of ultraviolet (UV) light. In the hydrogel, a three-dimensional (3D) network structure is formed through crosslinking. After undergoing a fracture under an external pressure, the hydrogel can rapidly heal itself through crosslinking due to a ligand-receptor interaction and a multi-hydrogen-bond interaction, which bio-mimicks a natural ligand-receptor interaction to realize the dynamics of the hydrogel material. The high antiomicrobial activity of vancomycin imparts the functionality of the hydrogel material; and the physiologically-derived monomer improves the biocompatibility and reduces the biological toxicity.