57 results about "Antimicrobial" patented technology

Feed additives including Chlamydomonas reinhardtii and a medium-chain fatty acid provide reduced risk of bacterial infection in animals. The feed additives are administered to animals in feed compositions.

A dynamic antimicrobial hydrogel based on natural receptor-ligand recognition, and a preparation method and use thereof are provided. A ligand vancomycin and a receptor AA-based material each are first modified with a modification material, and then a photoinitiator is added to prepare a hydrogel material under irradiation of ultraviolet (UV) light. In the hydrogel, a three-dimensional (3D) network structure is formed through crosslinking. After undergoing a fracture under an external pressure, the hydrogel can rapidly heal itself through crosslinking due to a ligand-receptor interaction and a multi-hydrogen-bond interaction, which bio-mimicks a natural ligand-receptor interaction to realize the dynamics of the hydrogel material. The high antiomicrobial activity of vancomycin imparts the functionality of the hydrogel material; and the physiologically-derived monomer improves the biocompatibility and reduces the biological toxicity.

A general formula for lysins based on which the activity and functionality are further screened and 24 lysins are identified and further investigated, nine of which are characterized. These lysins exhibit potent bactericidal activity, capable of lysing multiple species of Staphylococcus, Streptococcus, and / or Enterococcus; demonstrate robust environmental resistance and stability, retaining activity under varying temperatures, NaCl concentrations, pH levels, and in immune serum; and effectively treat localized and systemic infections. These lysins and their variants are promising as antimicrobial agents for eradicating bacteria, preventing bacterial infections, or treating bacterial infections (caused by genera Staphylococcus, Streptococcus, and / or Enterococcus).

The present invention relates to a peelable wound dressing system configured to maintain a controlled wound environment while enabling repeated access for treatment. The system includes a flexible base layer adhered to skin and a transparent peelable cover affixed by a resealable attachment mechanism. The cover is configured for multiple peel-and-reseal cycles, permitting wound inspection and treatment without removing the base layer. Optional features include antimicrobial agents in the base layer, anti-fog treatments in the cover, perforations or catheters for exudate drainage, and access pathways for lavage, infusion, or drug delivery. In some embodiments, sensor networks and wireless communication circuits are integrated into the cover or base to monitor wound and skin parameters, with power supplied by micro-batteries, passive RFID / NFC, or energy-harvesting elements. These features collectively improve infection control, visualization, treatment access, monitoring, and extended wear, addressing critical unmet needs in human and veterinary wound care.

Methods and systems are provided for infusing a crystalline and / or porous solid with a desired fluid, particularly an antimicrobial agent, as well as infused crystalline and / or porous solids produced thereby. Solids which may be infused with an antimicrobial agent according to the invention include erythritol, table salt, table sugar, baking soda, calcium carbonate, acetic acid, ascorbic acid, and marshmallow.

The utility model relates to the technical field of medicine delivery device, concretely to a kind of ureter delivery device suitable for antibacterial microsphere sustained release, including delivery structure and delivery pipe, delivery structure includes liquid storage cylinder, the left end of liquid storage cylinder is threadedly connected with cylinder cover, the left end of cylinder cover is equipped with connecting end, the input end of delivery pipe is equipped with the connecting sleeve threadedly connected with connecting end, piston for pushing antibacterial microsphere is equipped in liquid storage cylinder, the right side of piston is connected with push rod by bolt, the right end of push rod passes through the inner wall of liquid storage cylinder to outside, the lower portion of liquid storage cylinder is equipped with uniform speed drive structure for driving push rod left and right movement.The ureter delivery device suitable for antibacterial microsphere sustained release, the advancing speed of piston is controlled by uniform speed drive structure, and the physical speed-limiting effect of porous septum to microsphere passing is combined, antibacterial microsphere can be continuously released into urinary tract at constant and slow rate, overcome the problem of drug concentration sudden rise and sudden drop in traditional administration mode.

The invention provides novel compounds of formula (I), stereoisomers and pharmaceutically acceptable salts thereof: (wherein: Q is a lipophilic, zinc chelating moiety which is selective for Zn2+ ions; L1 is a covalent bond or a C1-6 alkylene chain in which one or more -CH2- groups of the alkylene chain are optionally replaced by a group independently selected from -CO- and -NR4- (where R4 is H or C1-3 alkyl); Y is selected from the following groups: (II) and (III) (where each R5 is independently H or C1-3 alkyl; and R6 is H or C1-3 alkyl); L2 is a covalent bond or a C1-6 alkylene chain in which one or more -CH2- groups of the alkylene chain are optionally replaced by a group independently selected from -CO- and -NR7- (where R7 is H or C1-3 alkyl); R is -OH, -O-C1-6 alkyl, -O-(CH2)p-O-CO-C1-6 alkyl (where p is an integer of 1 or 2) or -O-CH(CH3)-O- CO-C1-6 alkyl; each R1 is independently selected from halogen and C1-3 alkyl; each R2 is independently selected from halogen and C1-3 alkyl; R3 is H or C1-3 alkyl; n is an integer of 0 or 1; and m is an integer of 0 or 1). The compounds according to the invention are selective zinc chelators that find use as adjuvants in the treatment of bacterial infections and / or bacterial biofilms that harbour such infections. For use in such treatment, the compounds are used in combination with an antibacterial agent, for example a β-lactam antibiotic. The invention further provides a triple combination therapy for use in the treatment of bacterial infections and / or bacterial biofilms which comprises co-administration of the compounds to a subject in combination with a β-lactam antibiotic and a serine β-lactamase inhibitor.

This invention is related to the fields of medical biotechnology, nanobiotechnology, and nanomedicine. It involves a nanomedicine product that can release HOC1 (hypochlorous acid) at the tumor site in a controlled manner to treat lung cancer. HOC1 is a potent antimicrobial and antitumor agent that can target tumor tissues while minimizing damage to healthy tissues. The produced nanoparticles have a two-layer structure: the inner layer contains alginate, PFP (perfluoropentane), and Ca(OCl)2 to release HOC1, and the outer layer has a chitosan coating with folate and salicylic acid for targeting and proton release. The production process involves nanoemulsion and coating with the ionic gelation technique. When the nanoparticles are delivered to the lungs and targeted to cancer cells with folate, ultrasound radiation triggers the release of HOC1 to induce apoptosis and destroy cancer cells effectively, reducing side effects and improving treatment outcomes for lung cancer patients.

A disinfection cap is described for connection to a medical connector, the disinfection cap including a housing having a top wall and sidewall forming a cavity, a blockage feature disposed on the top wall of the cavity, the blockage feature for fluidly blocking a hub of a luer connector, disinfectant or antimicrobial agent disposed within an open cell foam structure within the cavity. The open cell foam structure releasing the disinfectant or antimicrobial agent as the open cell foam structure is depressed by the hub of the luer connector.

A method for dyeing a fabric has the steps of adding a fabric to a jet dyeing machine containing water, adding a scouring agent to the jet dyeing machine, heating the water and cooling the water, removing the water from the jet dyeing machine and refilling with water, agitating the fabric in the jet dyeing machine, adding a dye, a leveling agent, and a dispersing agent to the jet dyeing machine, heating the refilled water and cooling the refilled water, removing the refilled water from the jet dyeing machine and refilling with water, heating the refilled water to a certain temperature, agitating the fabric in the jet dyeing machine, adding a surfactant to the jet dyeing machine, maintaining the refilled water at the certain temperature and cooling the refilled water, removing the refilled water from the jet dyeing machine and removing the fabric from the jet dyeing machine.

The present invention provides novel mitochondria-targeted Atovaquone compounds (Mito-ATO), a mitochondria-targeted derivative of Atovaquone, and methods of using such compounds. Methods of treating cancer using mito-ATO are also provided. Methods of enhancing an anti-tumor immune response by administering mito-ATO are further provided.

A multispectral photonic imaging system and associated methods are disclosed for classifying wound tissue and generating customized therapeutic wound dressings. The system employs wavelength-specific optical sources and integrated image sensors to capture multispectral reflectance data from a wound, enabling computational classification of distinct tissue types such as granulation, slough, and necrosis. A three-dimensional (3D) digital model of the wound is constructed using spatial data from depth sensors. The classified 3D wound model facilitates automated design of patient-specific dressings, featuring heterogeneous regions tailored with therapeutic compounds like antimicrobial agents, analgesics, collagen scaffolds, and hydrogel matrices precisely aligned to corresponding tissue classifications. Additional imaging modalities, including thermal and ultrasound sensors, can be integrated to enhance classification accuracy and inform targeted therapeutic placement, providing a comprehensive and personalized approach to wound management for medical and veterinary applications.

Novel compositions are described, each comprising at least one active constituent that has a 12-carbon atom backbone as a 12-carbon chain base structure having at least a sub-terminal nitrogen and no terminal amino group. One of the active constituents is Boc-12-Ado-OH (BOA) and / or N,N-dimethyldodecylamine N-oxide (LO). Novel particle or liposomal compositions comprising at least BOA and / or LO may be prepared with an emulsifier and / or lipid and optionally a biopolymer, and may be formulated into pharmaceutically acceptable formulations and / or medicaments with or without one or more pharmaceutically acceptable carriers or excipients for utilization as an antimicrobial against one or more microbial pathogens. The novel antimicrobial compositions have broad-spectrum growth inhibitory or other destructive activity against microbial pathogens, biofilms produced by one or more pathogens, and biofilm infections.

The disclosure provides for novel antimicrobial agents, methods of making, and methods of use thereof.

Provided herein are laminated films with active agents, such as volatile anti-microbial agents, suitable for use as food packaging materials. Also provided herein are bags made from such laminated films, as well as methods of manufacturing such laminated films.

A composition having an additive or component having an antimicrobial or a preservative property, and 3-phenylpropanol or a member of the phenylpropanoid family is provided. A composition having a polymer, an organic acid, and 3-phenylpropanol or a member of the phenylpropanoid family is provided as well as a method(s) of using.

This invention is a high-potency medicinal oil composition and industrial processing method designed to prevent and treat acute and chronic respiratory tract infections, including sinusitis and tonsillitis, in a manner that breaks down the drug-resistant properties of pathogens (Antimicrobial A89. የ65ራርት1ረሰ6). The invention has a well-established framework for producing a precise 1 liter (1000 ML) pure liquid product with consistent quality.

A formulation for manufacturing an antimicrobial article, said formulation comprising 25 to 75 weight parts of a PVC resin; 20 to 40 weight parts of a plasticizer; 10 to 30 weight parts of a solvent diluent; 0.001 to 1% by weight, and preferably 0.001 to 0.3% by weight of a singlet oxygen generating dye.

An antimicrobial illumination system utilizes non- ultraviolet (non-UV) visible light, centered around 405 nm, to inhibit bacteria, fungi, mold, and yeast on stored food, cannabis, and healthcare products. Metal-clad printed circuit boards (MCPCBs ) of various geometries embed the LEDs and are integrated into lids, countertops, tabletops, and storage enclosures. The system provides continuous or intermittent antimicrobial illumination that is safe in occupied environments and preserves product quality without UV-induced degradation.The MCPCB integrates antimicrobial functionality, structural support, and thermal management in a single unit suitable for food, cannabis, and healthcare storage, as well as cosmetic and therapeutic uses.

OCR10KL (09 / 03 / 2569) This invention proposes a glove product with a nanoemulsion solution applied to the surface, composed of polymers. Long chain antimicrobial agents, antimicrobial enhancers, stabilizers, and intermediates containing... The preparation process involves mixing the stabilizers and intermediates together, then adding the polymer. The long-chain antimicrobial agent is mixed thoroughly, and then an enhancer is added to the resulting solution. Disinfection is achieved by mixing the components thoroughly and allowing them to set, resulting in a nanoemulsion solution. The solution is then used... The obtained nanoemulsion was prepared as gloves with the nanoemulsion solution applied to the surface.

Novel compositions and systems for closure of wounds with antimicrobial effectiveness are disclosed. The compositions provide devices of improved flexibility and elasticity and are readily applied to wound sites or over wound closure devices. The present invention is also directed to a novel platinum catalyst for use in such compositions. The catalyst provides for rapid curing on topical surfaces such as skin and bonds to such surfaces in about 2 -5 minutes.

This application provides a method for forming an antimicrobial coating on the surface of an implantable device and the implantable device itself. The method for forming an antimicrobial coating on the surface of an implantable device includes the following steps: placing the implantable device in an isolation box; setting an antimicrobial carrier assembly on the outer surface of the isolation box and / or the inner surface of a sterile barrier packaging; placing the isolation box in the sterile barrier packaging and sealing it to obtain a packaging system; sterilizing the packaging system with ethylene oxide; and vacuum dehydrating the ethylene oxide-sterilized packaging system. This method utilizes the antimicrobial carrier assembly in the packaging structure to diffuse an antimicrobial agent onto the surface of the implantable device during the sterilization and dehydration cycle, enabling the originally uncoated implantable device to acquire stable and controllable surface antimicrobial properties, thereby improving the antimicrobial capability of the implantable device.

An integrated disinfection device is described syringe assembly having two integrated disinfection units assembled to a syringe for disinfecting and sterilizing corresponding medical connectors, specifically access ports of corresponding medical connectors. The integrated disinfection unit includes a first cup and a second cup. The first cup having a chamber containing a first absorbent material, a first disinfectant or an antimicrobial agent in the first cup, and a first peelable seal. The second cup having a chamber containing a second absorbent material, a second disinfectant or an antimicrobial agent in the second cup, and a second peelable seal. A threaded connection is disposed on the bottom exterior surface of the first cup having threads that are sized and pitched to engage threads of a luer lock collar on the distal end of the syringe barrel to allow the first cup to be connected to the syringe assembly. The second cup and the syringe assembly are interlocked through interference fit or snap fit of the thumb press of the syringe and ledge of the second cup.

[0061] Ready-to-use tile / stone adhesive formulations that at least include an acrylic-styrene low- medium Tg latex binder, an acrylic-styrene high temperature resistant latex binder, an acrylic- styrene high Tg latex binder and a liquid hydraulic cement binder The present RTU adhesives may further include one or more of the following: a tackifier, in-can stabilizer present, anti-microbial, adhesion promoter, sand, pigment, one or more fiber materials, one or more thickeners, one or more filler materials, and / or a crosslinker. The invention is further directed to methods of bonding tile to a substrate using the various RTU adhesives of the invention in combination with an alkaline activator solution, as well as bonding systems that include the present RTU adhesives of the invention in combination with an alkaline activator solution.

Disclosed herein is a method of treating a surface. Such a method can comprise at least: (a) providing a liquid composition comprising at least a solvent, antimicrobial agent, and alpha-glucan derivative, and (b) contacting the liquid composition with a surface, thereby providing antimicrobial activity to the surface. Further disclosed are compositions comprising various alpha-glucan derivatives, and applications of using these derivatives.

The invention relates to a method for obtaining a gramicidin S extract from spore-forming Bacillus belonging to the genus Aneurinibacillus, characterised by comprising a solid-liquid extraction step using a solvent selected from the group comprising lactic acid, acetic acid, a biosurfactant extract obtained from corn steep liquors, or combinations thereof, at a temperature equal to or less than 40 °C. The invention also relates to the use of the gramicidin S extract obtained as an antimicrobial agent in the cosmetic and agrochemical industries, and as an antibiotic in the pharmaceutical industry.

The invention relates to a double-layered nanofibre diabetic toe / heel / foot protective galosh and production method, which is bio-based thermoplastic polyurethane and chitosan-based, aloe vera-enriched, simultaneously exhibiting antimicrobial / antifungal properties, wound healing-inducing, soft, ergonomic, porous, breathable, low moisture retention capacity, high air and water vapour permeability, double-layered nanofibre diabetic toe / heel / foot protective galosh and their production method.

The application discloses a multimodal antibacterial biological heterojunction, a preparation method and application thereof, and comprises the following steps: S1, preparing a dispersion liquid of single-layer Ti3C2 nanosheet; S2, preparing Fe and Cu doped metal organic framework material: FeCu-MOF; S3, compounding the single-layer Ti3C2 nanosheet and the FeCu-MOF to prepare the multimodal antibacterial biological heterojunction. The MXene / FeCu-MOF heterojunction is innovatively constructed, the band structure and near-infrared plasmonic effect are regulated, the directional transfer of electric charges is effectively promoted, the chemical dynamic therapy (CDT) and photodynamic therapy (PDT) effects are significantly enhanced, and the synergistic effect with photothermal therapy (PTT) is generated. The application designs a new multimodal non-antibiotic treatment strategy, which can realize efficient killing and removal of methicillin-resistant Staphylococcus aureus.