The invention discloses an efficient inactivation method for microorganisms on the surface of a sterile
bottle, which comprises the following steps: S1, cleaning the surface of the sterile
bottle by using clear water and a neutral
cleaning agent, and
drying the surface by using
compressed air until no
residual moisture exists; s2, 250-260 nm low-pressure mercury lamp equipment is fixed to the side wall of the refrigerating chamber, a lamp tube and the bottom face of a sterile
bottle are kept horizontal, the
radiation range covers the bottom of the bottle, the input
voltage is 200-240 V, and the working frequency is 50-60 Hz; s3, adjusting the
power output of the low-pressure mercury to be 30-80% of the rated power, recording the initial
irradiance value range to be 10-50 [mu] W / cm < 2 >, and measuring and calibrating the
irradiance by using a standard irradiatometer; s4, a low-pressure mercury lamp is started to continuously irradiate the bottom face of the sterile bottle, the
irradiation time is calculated according to the inactivation dosage and the actually-measured
irradiance, the low-pressure mercury lamp is fixed to the side wall of the refrigerating chamber, it is ensured that a lamp tube and the bottom face of the sterile bottle are kept horizontal, the distance and the included angle are controlled, and uniform and effective covering of
UVC radiation on the bottom face of the sterile bottle is achieved; therefore,
irradiation dead angles can be eliminated to the greatest extent.