3187results about How to "Low cost of treatment" patented technology

This invention provides methods for non-invasively monitoring patients with congestive heart failure (CHF) and for reporting and / or warning of changes in the patients' status. The methods gather physiological data and combine the data into parameters by which the severity of CHF can be judged. Preferred parameters include periodic breathing and heart rate variability. This invention also provides systems for carrying out these methods which permit patients to engage in their normal daily activities. Preferably, physiological data analysis is performed by a portable electronic unit carried by the patients.

The present invention relates to an ultrasound treatment clamp. The ultrasound treatment clamp comprises ultrasound therapy applicators and handles connected to the ultrasound therapy applicators. The handles are clamp-shaped. The two ultrasound therapy applicators with their central axes overlapping each other are mounted face to face on the two clamps of the clamp-shaped handles respectively. A parallel moving mechanism for keeping the two ultrasound therapy applicators in parallel when moving along with clamps is connected between the two clamps. The present invention has a compact structure, a convenient operation, a low treatment cost, a capability of quickly causing a coagulative necrosis of the diseased part. Furthermore, the present invention has an abroad use in treating many kinds of diseases.

The present invention relates to the use of compounds such as compounds of the xanthenone acetic acid class such as 5,6-dimethylxanthenone-4-acetic acid (DMXAA) for the treatment of cancer, wherein the compounds are administered gastrointestinally, preferably orally. More particularly, the invention is concerned with the use of such compounds, wherein the compound is delivered to the site of action in the patient to be treated in two or more doses.

A high-resistance buffer layer and a window layer (transparent conductive film) are successively formed by the MOCVD method to obtain the same output characteristics as in conventional film deposition by the solution deposition method and to simplify a film deposition method and apparatus. Thus, the cost of raw materials and the cost of waste treatments are reduced to attain a considerable reduction in production cost.After a metallic base electrode layer 1B and a light absorption layer 1C are formed in this order on a glass substrate 1A, a high-resistance buffer layer 1D and a window layer 1E are successively formed in this order in a multi layer arrangement on the light absorption layer 1C of the resultant semifinished solar cell substrate by the MOCVD method. Consequently, a film deposition method and apparatus are simplified and the cost of raw materials and the cost of waste treatments can be reduced.

The invention discloses a functional health-preserving treasure composition. By adopting the functional health-preserving treasure composition, the problems of poor health care effects and relatively large side effects existing in the prior art can be solved. The functional health-preserving treasure composition is characterized by comprising the following components in percentage by weight: 25-35% of foods and medicines for enriching qi and blood, 15-25% of foods and medicines for tonifying yang and astringing, 15-25% of foods and medicines for activating blood circulation and dissipating blood stasis, 5-15% of foods and medicines for nourishing the heart and tranquilizing mind, 5-15% of foods and medicines for tonifying yin and invigorating the stomach and 1-5% of foods and medicines for warming interior and removing toxicity. By adopting the functional health-preserving treasure composition disclosed by the invention, the immunity of a human body can be significantly enhanced, and the disease resistance can be strengthened so as to ensure that the physique of the human body can be significantly superior to that of the general population, and cold catching times and frequencies can be greatly reduced.

The invention discloses a TCR<->(T Cell Receptor) / PD-1<-> double-negative T cell and a construction method thereof. Separated peripheral blood mononuclear cells are activated into T cells and TCRs and PD-1 are knocked out through a CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) / Cas9 gene editing technology; the TCR<-> / PD-1<-> double-negative T cell is separated through a magnetic bead. The TCR<-> / PD-1<-> double-negative T cell prepared by the invention can be used for adoptive cell immunotherapies of tumors, including DC-CIK (Cytokine-Induced Killer), CTL (Cytotoxic T-Lymphocyte), TIL (Tumor Infiltrating Lymphocytes), CART (Chimeric Antigen Receptor Therapy) and the like. The TCR<-> / PD-1<-> double-negative T cell disclosed by the invention can be selected from other homologous and xenogenous healthy donators, so that the cell gets rid of limitation of current disease conditions of patients when being applied to the adoptive cell therapy; the cell can be prepared in a large batch in advance and the therapy cost is reduced.

A method has been invented for separating components of a wastewater stream, the stream containing water, oil (e.g. heavy oil and / or light oil), undesirable organic material (solid and / or liquid), and contaminating solids, the method including feeding a wastewater stream to a first pre-treatment unit producing a first pretreated stream, feeding the first pretreated stream to a first centrifuge for centrifugal separation, producing a first liquid centrifuged stream, and a second liquid stream, and feeding the first liquid centrifuged stream to a second centrifuge producing a resultant centrifuged stream of recoverable oil and a water phase centrifuged stream which can be treated further or fed back to a source for re-use. The source may be a facility from the group including refineries, chemical plants, paper mill plants, and oil and gas processing facilities.

A spiral reverse osmosis membrane element of the present invention includes a plurality of bag-shaped reverse osmosis membranes, permeated liquid passage members arranged inside the reverse osmosis membranes, and a plurality of feed liquid passage members interposed between the reverse osmosis membranes, those membranes and passage members being wound around an outer surface of a hollow pipe in a manner that only the interiors of the reverse osmosis membranes communicate with through-holes formed in the surface of the hollow pipe. Each of the feed liquid passage members is a mesh member having series of quadrilateral meshes formed by a plurality of linear members crossing each other. Two opposite cross-points out of four cross-points of each of the quadrilateral meshes are in line in parallel with an axial direction of the hollow pipe. And relations 2 mm<=X<=5 mm and X<=Y<=1.8X are both satisfied where X denotes a distance between the cross-points in a direction perpendicular to the axial direction of the hollow pipe and Y denotes a distance between the cross-points in the axial direction of the hollow pipe.

A medical filtering machine for the hemodialysis is composed of main body with console panel, blood loop consisting artery loop and vein loop, liquid-supplementing loop, water channel system and operation-control system. Said water channel system consists of reverse osmosis jointer, heat exchanger, heater, gear pump, deaerating unit, two concentrated liquid pumps, mixer, ion concentration monitor, volume balance and ultrafiltration unit, and endotoxin filter.

The invention discloses a motor function rehabilitation monitoring system based on a wireless body area network. The system comprises a sensor terminal node, a wireless gathering node, a wireless body area network gateway, a personal terminal, a remote medical terminal and an information feedback system, wherein the sensor terminal node comprises a medical sensor, a signal conditioning circuit, a microprocessor unit and a wireless transceiver unit which are sequentially connected, the medical sensor sends collected data into the signal conditioning circuit for preprocessing, and the wireless transceiver unit is controlled to perform wireless transmission after the data is processed by the microprocessor unit; the data collected by the sensor terminal node sequentially passes through the wireless gathering node and the wireless body area network gateway and is respectively transmitted into the personal terminal and the remote medical terminal, and the data is transmitted into the information feedback system after being processed by the remote medical terminal, and is displayed by a 3D model built through the information feedback system. The monitoring system can be used for monitoring the exercise rehabilitation situation of a patient in real time, providing reasonable guidance and advices for subsequent rehabilitation training and improving the rehabilitation training effect.

The invention discloses a medicament for treating deficiency of kidney, frequent micturition, urgent urination and prostatitis, which is prepared from 38 Chinese medicinal herbs: common curculigo rhizome, tuber fleeceflower root, ginseng, hippocamp, common macrocarpium fruit, malaytea scurfpea, siberian solomonseal rhizome, hairy antler, songaria cynomorium herb, root of red-rooted salvia, sevenlobed yam rhizome, epimedium, astragalus, raw rehmannia root, prepared rehmannia root, cochinchnese asparagus root, ophiopogon root, shizandra berry, medlar, cinnamomvine, white poria, seal's genitals, hawthorn fruit, raspberry, chaff flower root, platycladi seed, eucommia bark, Chinese angelica, medicinal indianmulberry root, south dodder seed, desertliving cistanche, polygala root, phellodendron, anemarrhena root, cassia bark, placenta, prepared common monkshood daughter root and black sesame seed. The medicament has the advantages of addressing both symptoms and root causes along with appropriate compatibility, good curative effect, short treatment course, high cure rate, low recurrence rate, no toxic or side effect, convenience for application, low treatment cost and the like.

Devices and methods can be used for artificial cardiac pacing and / or resynchronization. For example, this document provides improved electrodes for stimulating and sensing electrical activity of the heart, and provides pacing and resynchronization systems incorporating such electrodes. While the devices and methods provided herein are described primarily in the context of pacing, it should be understood that resynchronization can additionally or alternatively be performed in an analogous manner, and that the scope of this disclosure includes such subject matter.

The invention discloses a PD-1 gene recombinant virus. The collection number of the recombinant virus Lenti-PD-1-Puro is CCTCC No:V201601. According to the PD-1 gene recombinant virus, PD-1gRNA sequences are cloned into a retrovirus plasmid Lenti-CRISPR / Cas9-Puro, and a PD-1 recombinant virus plasmid Lenti-CRISPR / Cas9-PD-1-Puro is obtained; then the PD-1 recombinant virus plasmid Lenti-CRISPR / Cas9-PD-1-Puro, a plasmid pSPAX and pMD2.G are jointly transfected by 293T cells, and packaging of the recombinant virus Lenti-PD-1-Puro is completed. After T cells of peripheral blood of tumor patients are infected by the PD-1 recombinant virus, PD-1 on the T cells is successfully knocked out, the inhibitory state of the T cells of the tumor patients is relieved, the capacity of attacking tumor cells of the T cells embellished by the PD-1 recombinant virus is recovered accordingly, and the effect of immune cell treating is achieved.

Disclosed is a Chinese medicament for treating lumbago caused by deficiency of the kidney, wherein the recipe includes pubescent angelica root, large-leaf gentian root, Chinese angelica root, root of herbaceous peony, prepared rhizome of rehmannia each 12g, Loranthus mulberry mistletoe 18g, drynaria, eucommia bark, achyranthes root, pilose asiabell root, dipsacus root, Clematis chinensis each 15g, ledebouriella root, rhizome of Sichuan lovage each 9g, astragalus root 30g, cinnamon twig 6g, bitter cardamon, lindera root each 12g, asaryl, processed radix aconiti each 15g, prepared aconite root, dried ginger each 18g, curculigo rhizome, epimedium each 12g, spatholobus stem, safflower, curcuma aromatica, red peony root each 10g. The Chinese medicament has simplified recipe, easy preparing process and low price.

The invention discloses a Chinese herbal medicine for treating cellulitis. The Chinese herbal medicine is prepared from the following medicines in parts by weight: 25-35 parts of honeysuckle, 25-35 parts of wild chrysanthemum, 25-35 parts of dandelion, 15-25 parts of Philippine violet herb, 5-15 parts of semiaquilegia adoxoides makino, 25-35 parts of goldthread root, 25-35 parts of radix scutellariae, 25-35 parts of amur corktree bark, 15-25 parts of cape jasmine, 15-25 parts of climbing groundsel herb, 10-25 parts of broomjutre sida herb and 15-25 parts of all-grass of Japanese violet. The Chinese herbal medicine is prepared by adding 1800 parts by weight of water, after the water is boiled, decocting the medicines with slow fire for 20-30 minutes, filtering the decoction and collecting the supernatant, adding 1800 parts by weight of water and decocting the supernatant three times, uniformly mixing the supernatant decocted three times, then bottling the supernatant respectively and sterilizing the supernatant under a high temperature for later use. Honeysuckle is taken as the monarch, dandelion and wild chrysanthemum are taken as the ministers, Philippine violet herb, semiaquilegia adoxoides makino, goldthread root and radix scutellariae are taken as the assistants, and amur corktree bark, cape jasmine, climbing groundsel herb, broomjutre sida herb and all-grass of Japanese violet are taken as the guides. The Chinese herbal medicine has the following beneficial effects: the Chinese herbal medicine is convenient to prepare and use, is safe and does not have side effects.

The present invention is to provide an electromagnetic wave shielding material including a transparent substrate and a convex pattern layer composed of a conductive composition formed in a prescribed pattern on the transparent substrate, wherein the conductive composition contains conductive particles and a binder resin; and in observation of a transverse cross section of the convex pattern layer by electron microscopic photography, at least a part of the conductive particles has a fused continuation and a method for manufacturing the same. The electromagnetic wave shielding material and the method for manufacturing the same include a configuration capable of achieving a lower surface resistivity in an electromagnetic wave shielding material which is required to achieve a much more reduction in a line width of the pattern, specifically, a reduction to a line width of not more than 30 μm, and more preferably not more than 15 to 20 μm and a treatment method capable of reducing the surface resistivity by an easy and short-time treatment.

The present invention is concerned with delivering a pharmaceutical composition to the brain of a mammalian subject for treating brain diseases or disorders. The process includes the steps of: (i) providing a dispersion of the pharmaceutical composition as particles having an average particle size of from about 150 nm to about 100 microns, and (ii) administering the dispersion to the mammalian subject for delivery to the brain of a portion of the pharmaceutical composition by cells capable of reaching the brain. The dispersion of the pharmaceutical composition as particles, for example, can be phagocytised or adsorbed by the cells prior or subsequent to administration into the mammalian subject. The dispersion of the pharmaceutical composition can be administered to the central nervous system or the vascular system. After administration, the loaded cells transport the pharmaceutical composition as particles into the brain.

The invention discloses a medical grinding cutter. The cutter comprises a knife tube component and a grinding head, wherein the grinding head is mounted at the front end of the knife tube component; the grinding head can be driven for pitching and self-rotation; the tail end of the grinding head in the circumference direction is hinged to an inner knife tube in a transmission manner; a flexible transmission section is positioned at the front end of the inner knife tube and used to be hinged to the tail end of the grinding head, and can transfer torque. According to the invention, the medical grinding cutter adopts a direct hinging structure to transfer the transmission between the inner knife tube and the grinding head, can conduct a pitching motion, and adopts a flexible transmission structure to compensate axial deviation caused by pitching and transmission; the transmission structure is simple, and the transmission chain is shorter, which facilitates stable control, so that the operative efficiency is improved; the medical grinding cutter also adopts a structure capable of adjusting both the pitching and circumferential positions of the grinding head, so that the universal orientation adjustment is realized; the medical grinding cutter has a good adaptation to an operative site and higher precision; the operative process efficiency can be improved; the pain of the patients can be minimized, and meanwhile, the treatment cost can be reduced.

The invention provides a long-acting microsphere injection as an antidiabetic medicament, the long-acting microsphere injection comprises liraglutide, PLGA (poly(lactic-co-glycolic acid)), excipients and a surfactant, and the invention simultaneously relates to a preparation method of the injection. Liraglutide long-acting sustained-release microspheres provided by the invention are designed to perform subcutaneous injection once every 28 days, thereby greatly reducing treatment burden on a patient, improving medication compliance and reducing treatment cost; simultaneously, results of in vitro release studies, animal experiments and the like prove that the obtained sustained-release microspheres can slowly release a medicament for a long time in vitro and in vivo.

A method for decreasing or shortening the length of time required to complete a surgical procedure by the application of hyaluronic acid to the surgical site, and for wound management by topical application of hyaluronic acid to a wound by syringe through a thin film dressing. The method of wound management results in accelerated wound healing time. The solution of hyaluronic acid may include an effective amount of a polysulfated glycosaminoglycan for stimulating macrophage activity at the surgical wound site.

The invention relates to a manufacturing method of a bracketless invisible appliance. The manufacturing method comprises the following steps: obtaining the oral data of a patient and establishing a three-dimensional model for an oral cavity of the patient according to the oral data, wherein the three-dimensional model comprises tooth data and gum data; designing a correction scheme, adjusting the position of a tooth to be corrected to a target correction position and obtaining a dental model; generating a cutting line on the dental model; forming the three-dimensional dental model into an entity dental model in a quick forming mode or a 3D printing mode and covering a diaphragm on the entity dental model in a vacuum diaphragm pressing way; cutting the entity dental model coated with the diaphragm by taking the cutting line of the three-dimensional dental model as a cutting path and demolding the diaphragm after the completion of cutting so as to form the appliance. The bracketless invisible appliance is obtained by the manufacturing method. The bracketless invisible appliance and the manufacturing method thereof have the advantages of high processing efficiency, large bearing capacity and difficulty in breakage.

The invention discloses a Chinese medicinal preparation for treating urolithiasis, which is prepared from niter, chicken's gizzard-membrane, alum, gardenia jasminoides, Japanese climbing fern spore, longhairy antenoron herb, cluster mallow fruit, herba pyrrosiae, virgate wormwood herb, amber, cuttlebone, pangolin scales, cowherb seed, spreading hedyotis herb, frankincense, myrrh, white paeony root, lalang grass rhizome, clematis root, corydalis root, radix curcumae, talc, pink herb, medicinal cyathula root, giant knotweed rhizome, astragalus, mongolian dandelion herb, mole cricket, plantain seed, herba polygoni avicularis, yellow croaker ear-stone, common burreed rhizome, zedoary, gleditsia thorn, dried orange peel, ephedra, oriental waterplantain rhizome, chinese waxgourd peel, notoginseng root, agaric, Chinese eaglewood, akebia stem, rhubarb and India madder root in a certain weight ratio. The Chinese medicinal preparation can be prepared into any common oral administration formulation. In a formula of the Chinese medicinal preparation, the medicaments have the good synergistic effect on the curative effect through reasonable compatibility, so the effects of inducing diuresis, treating stranguria and removing urinary calculus are achieved better, and the symptoms are removed. Compared with the prior art, the Chinese medicinal preparation has the advantages of quick response, high cure rate, relapse prevention, no toxic or side effect, low treatment cost and easy acceptance by patients.

The invention discloses medicinal liquor for treating rheumatic arthritis and chronic infectious arthritis, which comprises the following raw materials in parts by weight: 33-38 parts of Chinese parsnip root, 8-13 parts of asarum, 28-33 parts of the root of bidentate achyranthes, 28-33 parts of ligusticum sinense oliver, 28-33 parts of notopterygium root, 28-33 parts of radix angelicae pubescentis, 23-28 parts of prepared monkshood, 28-33 parts of cassia twig, 28-33 parts of pawpaw, 28-33 parts of radix clematidis, 28-33 parts of cortex acanthopanacis, 28-33 parts of semen coicis, 28-33 parts of corydalis tuber, 28-33 parts of large-leaved gentian, 4-9 parts of long-noded pit viper, 28-33 parts of the root of fangji, 28-33 parts of rhizoma typhonii, 28-33 parts of ligusticum wallichii, 28-33 parts of zaocys dhumnade, and 7000-8000 parts of 50-60-degree white wine. The medicinal liquor disclosed by the invention has the advantages of being low in cost, high in curative rate and free from toxic and side effects; stimulation of the existing medicines on gastric mucosa is overcome; simultaneously, the medicinal liquor disclosed by the invention also has the functions of tonifying liver and kidney.

The invention discloses a special premix for heavy milker perinatal period, which comprises the following steps: drying traditional medicine additive; grinding; sieving with 200 order; mixing evenly; mixing vitamin evenly; mixing the traditional medicine additive and vitamin evenly; mixing microelement and health products evenly; getting mixture; adding into slow release agent; sieving with 80 order sieve; getting the product. This premix possesses distinctive curative effect and low cost.

The invention relates to a hollow fiber ultrafiltration composite membrane composed of the components in the following weight percent: 15-25% of membrane material, 5-15% of pore-making agent, 55-75% of organic solvent and 5-10% of lithium chloride; the membrane material is a mixture of chitosan and one of polysulfone, polyether sulfone, polyacrylonitrile, polymethyl methacrylate, or cellulose triacetate, wherein the chitosan accounts for 1-5% of the total weight of the raw material, and the average molecular weight of chitosan ranges from 300,000 to 1,000,000; the pore-making agent is one of polyvinylpyrrolidone, polyethyleneglycol, or polyvinyl alcohol, or a mixture thereof; and the organic solvent is one of N-methyl-2-pyrrolidone, dimethyl fomamide, dimethyl acetamide, or dimethyl sulfoxide. The invention has good bioactivity, biocompatibility, anti-coagulation property and other properties.

The invention provides a fusion protein used for detecting and treating human I-type diabetes mellitus and human II-type diabetes mellitus and obesity as well as a preparation and an application of the fusion protein. The fusion protein contains a human FGF21 or a mutant thereof and a human IgG2-Fc (hinge region -CH2-CH3) or a human IgG2-Fc mutant ( T250Q / M428L and T307Q / N434A), can improve the living condition of the obesity patients, reduce the blood sugar level of diabetics, effectively reduce aggregation and degradation of the FGF21 protein, and meanwhile prolong in vivo half-life period of the FGF21, and especially through the fusion of the FGF21 and the mutant and the IgG-Fc (T250Q / M428L and T307Q / N434A) mutant, the affinity with FcRn is enhanced, and in vivo half-life period of the FGF21 is further prolonged.

The invention discloses a normal full nutrient, which is characterized by being prepared into powder by using the following materials: zymolytic rice flour, polypeptide, caseinsodium, lactalbumin, malto dextrin, vegetable oil, milk powder, dietary fibers, mineral premix, vitamin premix and the like. The normal full nutrient is characterized in that: proteins and carbohydrates, which have high bioavailability and are easy to digest, are used to quickly and timely supplement nutrients and energy, which are required by the human body, so that the synthesis and repair of the tissues of the human body can be improved; and various of dietary fibers are added into the product, the gastrointestinal diseases such as astriction and diarrhea can be regulated in a bidirectional manner and the cure success rate of serious patients and the overall conditions of patients can be improved. Meanwhile, according to the gastrointestinal tract stress difference between serious patients in clinic, a low-permeability formula suitable for early intestinal nutritional support is designed for better improving and increasing the adaptability of gastrointestinal tracts.

The preparation method includes the following steps: modifying hepatic target compound onto degradable polymer (chitosan, polylysine, glucosan, agar, polyglutamic acid-benzyl ester, polyalanine) with biological compatibility, and adopting ion exchange or ultrasonic emulsification process to obtain the invented nano hepatic target bio-degradable medicine carrier material. The hepatic target nano particle solution has good target performance for liver, the medicine enriched rate in the liver can be up to 75%, and its slowly-released administration can be up to above 15 days.

The invention relates to 3D navigation equipment for non-invasive real-time operation positioning, which is characterized by comprising a laser positioning system and a space positioning device, wherein the laser positioning system is composed of a laser driving device, a work server, a digital signal shunt and a display, the laser driving device is in Bluetooth communication with the work server, and the work server, the digital signal shunt and the display are electrically connected; and the space positioning device is composed of a fixing slide rail, a two-way slide rail, a two-degree-of-freedom fixing slide block, a two-degree-of-freedom two-way slide block, a laser positioning rod and an operation channel which are mutually matched. According to the invention, path planning before an operation is realized through a computer, and an operation path can be spatially positioned accurately by visualized real-time registering of a focus point in the operation by the laser positioning system as well as the angle and depth control of the space positioning device; and the system is suitable for minimally-invasive orthopedic operations of any parts of patients.