8 results about "Type diabetes" patented technology

The invention relates to the technical field of medical biology, in particular to a chronic pancreatitis complication risk grading system based on exosome transcriptome data, and aims to solve the problems that existing chronic pancreatitis (CP) typing lacks molecular basis, complication risk prediction is weak and clinical transformation is poor. According to the system, plasma exosomes are extracted and sequenced, a functional characteristic gene set is constructed in combination with pancreas single cell data, CP is divided into three risk increasing subtypes by using a COCA algorithm, and finally 12 core miRNAs are screened to construct a BPNN diagnosis model. The invention proves that the plasma exosome can be used for staging classification of chronic pancreatitis for the first time, miRNA non-invasive accurate layering illness conditions can be detected through qPCR, the risk of fatty diarrhea and 3c type diabetes mellitus can be predicted, and the non-invasiveness, convenience, classification accuracy and result repeatability of the plasma exosome have clinical application and transformation advantages.

The invention discloses a traditional Chinese medicine composition for treating middle-jiao type diabetes as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 15-30 parts of herba eupatorii, 10-20 parts of radix astragali, 8-15 parts of radix codonopsis, 1-3 parts of gypsum, 6-12 parts of radix rehmanniae preparata, 6-12 parts of radix rehmanniae recen, 9-15 parts of Chinese yam, 18-30 parts of radix trichosanthis, 12-20 parts of rhizoma anemarrhenae, 12-20 parts of radix ophiopogonis, 9-15 parts of dendrobe, 9-15 parts of radix polygonati officinalis, 3-6 parts of safflower, 3-6 parts of coptis chinensis, 9-15 parts of radix scrophulariae, 9-15 parts of dogwood, 6-10 parts of liquorice and 9-15 parts of seville orange flower. , 9-15 parts of loquat flower, 6-12 parts of penthorum chinense pursh and 6-12 parts of angelica keiskei. The traditional Chinese medicine composition is suitable for nourishing yin, moistening the lung, clearing the stomach, clearing heat, moistening dryness and promoting the secretion of saliva or body fluid, has a positive regulation effect on blood sugar and blood fat of diabetes patients, and is used for middle-digestion diabetes.

The present application relates to the technical field of biotechnology, and discloses a plant Lactobacillus plantarum XKFY202518 and application of the plant Lactobacillus plantarum XKFY202518 in preparation of a type 2 diabetes auxiliary preparation for improving insulin resistance and regulating blood lipid, the plant Lactobacillus plantarum XKFY202518 has a preservation number of CGMCC No.34745 in China General Microbiological Culture Collection Center, and a preservation date of June 3, 2025.The plant Lactobacillus plantarum XKFY202518 separated by the present application can effectively reduce the fasting blood glucose level, insulin level, total cholesterol level, triglyceride level, low-density lipoprotein cholesterol level, alanine aminotransferase level and aspartate aminotransferase level of a diabetic mouse, and increase the high-density lipoprotein cholesterol level of the mouse serum, thereby improving the hyperglycemia and hyperlipidemia symptoms of a type 2 diabetes mouse.

The invention belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine composition for treating upper digestion type diabetes and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: 25 to 35 parts of herba eupatorii, 25 to 35 parts of radix codonopsis, 25 to 35 parts of radix rehmanniae recen, 25 to 35 parts of radix puerariae, 25 to 35 parts of radix trichosanthis, 20 to 30 parts of radix ophiopogonis, 15 to 25 parts of rhizoma coptidis, 15 to 25 parts of radix adenophorae, 15 to 25 parts of rhizoma anemarrhenae, 15 to 25 parts of rhizoma polygonati, 15 to 25 parts of poria with hostwood, 15 to 25 parts of corn stigma, 15 to 25 parts of folium mori, 5 to 15 parts of fructus schizandrae and 5 to 10 parts of liquorice root. The traditional Chinese medicine composition provided by the invention can be used for effectively treating the upper-digestion diabetes mellitus on the basis of the main pathogenesis of the upper-digestion diabetes mellitus according to medication experience and traditional Chinese medicine theories.

The invention provides a micro-pulse peristaltic pump type diabetes insulin pump which comprises a shell, a micro-pump medicine bin assembly, a micro motor and a gear assembly are arranged in the shell, and the micro-pump medicine bin assembly is detachably connected with the shell; a medicine bin containing insulin and a micro peristaltic pump used for pumping the insulin are arranged in the micro pump medicine bin assembly, and the two ends of a pump pipe of the micro peristaltic pump are connected with the medicine bin and an external medicine conveying guide pipe respectively. The micro motor is a flat motor, and the ratio of the diameter to the length of an armature of the micro motor is 8: 1. The insulin pump is different from a plunger type insulin pump existing in the current market, a power device adopts a micro peristaltic pump and is combined with a micro flat torque type motor, a speed reducing mechanism does not need to be arranged, the output torque is effectively increased in a limited space, and the dual requirements of the insulin pump for high-precision and low-power-consumption driving are met; the equipment is obviously simplified, and the weight of the equipment is reduced. Meanwhile, flexible supplement of liquid medicine can be achieved through the detachable medicine bin, the medicine bin can be repeatedly used, and the material consumption is reduced.

The invention discloses a traditional Chinese medicine composition for treating lower digestion type diabetes as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises fortune eupatorium herb, rehmannia root, trichosanthes root, Chinese yam, astragalus root, figwort root, dwarf lilyturf tuber, tree peony bark, oriental waterplantain rhizome, tuckahoe, dogwood, safflower, turmeric, Chinese magnoliavine fruit, liquoric root, monkshood, cassia twig, dendrobium flower, glossy privet fruit, epimedium herb, corn stigma and hippophae rhamnoides leaf. Through reasonable compatibility of the traditional Chinese medicinal materials, the traditional Chinese medicinal composition with a remarkable treatment effect on the lower digestion type diabetes mellitus is obtained.

The invention discloses toxin-expelling and kidney-tonifying paste for preventing diabetes from being converted into diabetic kidney and a preparation method of the toxin-expelling and kidney-tonifying paste. The application is prepared by the following steps: mixing raw materials including radix rehmanniae, angelica sinensis, raw rhizoma atractylodis macrocephalae, radix scrophulariae, rhizoma anemarrhenae and raw rhubarb according to a specific ratio, grinding into powder, adding a blender to prepare paste, and then preparing into a cylindrical medicinal cake. The preparation method is simple and convenient to use. Based on the traditional Chinese medicine dialectical theory, aiming at the pathogenesis of'yin deficiency and internal heat 'of patients with constipation type diabetes mellitus, when the application is used, acupoint application is combined with the effects of traditional Chinese medicines, the functions of viscera are conditioned, microcirculation is improved, and gastrointestinal stimulation caused by oral administration of medicines is avoided. Clinical tests show that the ointment can remarkably improve the symptoms of yin deficiency and internal heat and reduce the level of early renal injury markers, is good in safety and provides an effective traditional Chinese medicine non-drug intervention means for preventing and treating diabetic kidney diseases.

The invention relates to the technical field of diabetes, in particular to a multi-source data generation system for diabetes management decision support, comprising a multi-source data acquisition module, a preprocessing module, a decision analysis module, a classification module and a display module, the preprocessing module is connected with the multi-source data acquisition module, the decision analysis module is connected with the preprocessing module, and the classification module is connected with the display module. The classification module is connected with the decision analysis module, the display module is connected with the decision analysis module, a patient can input diabetes types into the decision analysis module through the classification module, and the decision analysis module can adjust a decision rule base in the decision analysis module according to the diabetes types input by the patient. Therefore, the system can help the patient to give accurate treatment suggestions according to different types of diabetes mellitus of the patient.