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276 results about "Rhizoma Coptidis" patented technology

Therefore, other common names of this herb are coptis rhizome, rhizoma coptidis, Chinese gold thread, Chuan lian, coptidis rhizoma, coptis chinensis root, coptis goldthread, etc. Commercially most of them are from cultivation and mainly produced in Sichuan, Yunnan, and Hubei.

UPLC (Ultra Performance Liquid Chromatography) map construction method and identification method for rhizoma menispermi medicinal material and formula granules

The invention discloses a rhizoma menispermi medicinal material and formula granule UPLC (Ultra Performance Liquid Chromatography) identification method, which is characterized in that specified values of relative retention time of the rhizoma menispermi medicinal material and formula granule are determined through a high performance liquid chromatography, and the relative retention time of a corresponding test solution is respectively within + / -10% of the corresponding specified values of the rhizoma menispermi medicinal material and formula granule. The method can effectively identify the rhizoma menispermi medicinal material and the formula granules, can be used for identifying rhizoma menispermi and counterfeit berba aristolochiae mollissimae and subprostrate sophora medicinal materials and formula granules, and can also be used for identifying rhizoma coptidis, cortex phellodendri, caulis sinomenii and other medicinal materials containing alkaloid components and formula granules. The method overcomes the defects of the existing method, and has the characteristics of simplicity in operation, good stability, rich chromatographic peak information amount, good repeatability and high stability.
Owner:劲牌持正堂药业有限公司 +1

Traditional Chinese medicine compound and preparation for reducing blood uric acid and relieving pain and preparation method thereof

The invention discloses a traditional Chinese medicine compound and preparation for reducing blood uric acid and relieving pain and a preparation method of the traditional Chinese medicine compound, belongs to the technical field of traditional Chinese medicine compounds, and solves the technical problem that at present, a medicine which does not have side effects and is used for treating hyperuricemia is lacked. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 10-30 parts of cortex phellodendri, 5-20 parts of rhizoma coptidis, 15-30 parts of rhizoma atractylodis, 20-40 parts of semen coicis, 10-30 parts of radix cyathulae, 10-30 parts of pawpaw, 3-5 parts of fried fructus evodiae, 15-50 parts of radix astragali, 5-15 parts of The traditional Chinese medicine composition has the effects of reducing blood uric acid, resisting inflammation and relieving pain, is reasonable in compatibility, complements each other and has a synergistic effect, and the effects of reducing blood uric acid, resisting inflammation and relieving pain are increased.
Owner:TEACHING HOSPITAL OF CHENGDU UNIV OF T C M

Traditional Chinese medicine gel plaster for treating gouty arthritis and preparation method thereof

The invention provides a traditional Chinese medicine gel patch for treating gouty arthritis and a preparation method thereof. The traditional Chinese medicine gel patch for treating gouty arthritis comprises at least a gel layer loaded with traditional Chinese medicine extracts; the traditional Chinese medicine extracts comprise the following raw materials: coix seed, phellodendron amurense, clematis root, radix scutellariae, atractylodes lancea, radix ophiopogonis, radix scutellariae, acer scutellariae, radix scutellariae, radix aconiti kusnezoffii, radix strychnii, frankincense, myrrh, angelica sinensis, safflower, cyathula root, radix paeoniae rubra, radix smilacis gracile, radix striatae, eucalyptus glomeratae, sophora flavescens, andrographis paniculatae, radix lobeliae, rhizoma coptidis, radix scutellariae, cassia twig, zanthoxylum bungeanum, and borneol; and a matrix of the gel layer comprises the following raw materials in parts by weight: silk fibroin, polyvinyl pyrrolidone, azido-polyethylene glycol-carboxylic acid, 1-ethynylcyclopropylcarboxylic acid, 2,5-dicarboxylic acid-3,4-ethylenedioxythiophene, and glycerol. The traditional Chinese medicine gel plaster of the present invention can achieve good therapeutic effects through percutaneous absorption.
Owner:GUANGZHOU HEYI MEDICAL TECH CO LTD

Pueraria qinlian decoction vesicle-like nanoparticles as well as extraction method and application thereof

The invention discloses a Gegen Qinlian decoction vesicle-like nanoparticle as well as an extraction method and application thereof, and belongs to the technical field of biological medicines. The method comprises the following steps: preparing a radix puerariae qinlian decoction stock solution; placing at 4-8 DEG C for 12-15 hours to obtain a gelatinous substance; carrying out low-speed centrifugation at 4-8 DEG C, and taking supernate, so as to obtain crude extract of the vesicle-like nanoparticles of the radix puerariae, radix scutellariae and rhizoma coptidis decoction; carrying out ultracentrifugation at 4-8 DEG C, discarding the supernatant, and carrying out PBS resuspension precipitation to obtain a crude product of the vesicle-like nano-particles of the Gegen Qinlian decoction; and centrifuging 16000g at the temperature of 4-8 DEG C for 10-15 minutes, taking supernate, and filtering by using a 0.22 mu m filter membrane, so as to obtain the vesicle-like nanoparticles of the Gegen Qinlian decoction. According to the Gegen Qinlian decoction vesicle-like nanoparticles as well as the extraction method and the application thereof, the bioavailability and the targeting property of effective components in the Gegen Qinlian decoction are remarkably improved through a nanocrystallization technology, the concentration of the medicine at the ulcerative colitis part is enhanced, and the treatment effect is effectively improved.
Owner:NORTHWESTERN POLYTECHNICAL UNIV

Chinese sage herb traditional Chinese medicine composition and application thereof

The invention discloses a Chinese sage herb traditional Chinese medicine composition and application thereof, and relates to the technical field of traditional Chinese medicine, the Chinese sage herb traditional Chinese medicine composition comprises radix sophorae flavescentis, cortex phellodendri, herba violae, coptis chinensis, radix scutellariae, dandelion, rheum officinale, fructus kochiae, cortex dictamni, fructus cnidii, raspberry, leonurus, hairyvein agrimony and radix cyathulae, the traditional Chinese medicine composition has the effects of soothing liver and spleen to relieve damp heat, clearing lower jiao to remove stasis and turbidity; rhizoma coptidis, radix scutellariae, herba violae and herba taraxaci have the effects of clearing heat, purging fire, eliminating dampness, detoxifying, relieving restlessness and relieving itching; rheum officinale and motherwort are combined to purge and clear heat and promote blood circulation to remove blood stasis. The raspberry, the hairyvein agrimony and the fructus cnidii are combined to tonify deficiency, tonify qi and warm the kidney, so that evil is eliminated, and yin and blood are not injured; the cortex dictamni and the fructus kochiae dispel wind, arrest itching, kill parasites and detoxify; the medicines are combined to achieve the effects of clearing heat, drying dampness, dispersing blood stasis, tonifying deficiency, killing parasites and relieving itching.
Owner:程玲

Microbial agent for preventing and treating fructus aurantii scab and preparation method thereof

The invention relates to the technical field of agricultural biology, and discloses a microbial agent for preventing and treating fructus aurantii scab and a preparation method of the microbial agent. The microbial agent comprises the following raw materials in percentage by weight: 10-13% of paenibacillus mucilaginosus; 15%-20% of trichoderma sp. 7%-10% of paecilomyces lilacinus; 5%-8% of bacillus pumilus; 7%-9% of mycorrhizal fungi; 5%-8% of streptomyces; 5%-9% of a coptis chinensis extract; 4%-7% of a sophora flavescens extract; 2%-4% of realgar; 1%-3% of a rheum officinale extract; 10%-13% of soybean meal; 5%-8% of a water-soluble fertilizer; 7%-9% of potassium fulvate; 1%-3% of chitosan; 0.5%-1% of trace elements; 3%-8% of humic acid; the raw materials are subjected to microbial flora amplification culture, plant antibacterial component light-shielding mixing and low-temperature mixing to effectively protect the microbial activity of the microbial agent, and step-by-step operation can avoid damage of high temperature and mechanical shearing to microorganisms, so that the microbial activity of the microbial agent is effectively protected. And the loss of microbial active ingredients is reduced by vacuum drying and low-temperature granulation processes.
Owner:INST OF PLANT PROTECTION JIANGXI ACAD OF AGRI SCI

Traditional Chinese medicine composition for promoting sleep and growth as well as preparation method and application of traditional Chinese medicine composition

The invention discloses a sleep-aiding and growth-promoting traditional Chinese medicine composition which is mainly prepared from the following traditional Chinese medicine raw materials by weight: 10-30 g of astragalus membranaceus, 5-15 g of roasted rhizoma atractylodis macrocephalae, 2-8 g of pericarpium citri reticulatae, 10-20 g of codonopsis pilosula, 5-15 g of rhizoma cimicifugae, 2-8 g of radix bupleuri, 2-8 g of angelica sinensis, 10-30 g of radix rehmanniae, 5-15 g of honey-fried licorice root, 10-20 g of Chinese yam, 5-15 g of cortex moutan, 5-15 g of rhizoma alismatis, 5-15 g of dogwood, 1-5 g of cinnamon, 5-15 g of poria cocos and 2-8 g of myristica fragrans. The traditional Chinese medicine is prepared from 5-15 g of radix aucklandiae, 1-5 g of rhizoma coptidis, 2-8 g of fructus amomi, 5-15 g of fructus crataegi, 5- Correspondingly, the invention further discloses a preparation method and application of the traditional Chinese medicine composition for helping sleep and growth. The traditional Chinese medicine composition has outstanding curative effects on poor sleep quality, slow growth, short body, easy cold constitution and adenoid hypertrophy at the same time, and has the effect of treating multiple diseases by one medicine.
Owner:FOSHAN GAOMING DISTRICT HOSPITAL OF TRADITIONAL CHINESE MEDICINE

Traditional Chinese medicine composition for treating liver cirrhosis and preparation method thereof

The invention discloses a traditional Chinese medicine composition for treating liver cirrhosis and a preparation method thereof, and belongs to the technical field of anti-liver cirrhosis traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: 10g of polyporus umbellatus, 10g of herba artemisiae scopariae, 10g of radix bupleuri, 10g of charred rheum officinale, 10g of rhizoma coptidis, 10g of charred radix scutellariae, 10g of fructus gardeniae, 15g of herba hyperici japonici, 10g of radix curcumae, 10g of rhizoma alismatis, 10g of radix paeoniae rubra, 10g of radix salviae miltiorrhizae, 10g of cortex magnoliae officinalis, 10g of fructus aurantii, 10g of rhizoma cyperi, 10g of rhizoma sparganii, 10g of rhizoma curcumae, 20g of plantain herb, 10g of turtle shell, 10g of pericarpium arecae, 25g of oven earth and 2g of charred colla corii asini. By providing the traditional Chinese medicine composition formula for treating the liver cirrhosis, the effective rate and the cure rate of the medicine for treating the liver cirrhosis are improved.
Owner:ZHONGSHAN SECOND PEOPLES HOSPITAL

Traditional Chinese medicine composition for improving cognition, emotion, memory and depression state as well as preparation method and application of traditional Chinese medicine composition

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for improving cognition, emotion, memory and depression states and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following components in parts by mass: radix scutellariae, rhizoma coptidis, radix puerariae, rhizoma anemarrhenae, bitter gourd, rhizoma zingiberis, stiff silkworm, American ginseng and radix notoginseng. Wherein the radix scutellariae and the rhizoma coptidis are monarch drugs and mainly attack the core pathogenesis; the radix puerariae, the rhizoma anemarrhenae and the pseudo-ginseng serve as ministerial drugs, assist monarch drugs and treat secondary pathogenesis; bitter gourd, rhizoma zingiberis, stiff silkworm and American ginseng are used as adjuvant drugs to regulate drug properties and treat and treat both symptoms and root causes; and radix puerariae and pseudo-ginseng are used as conductant drugs for guiding channels or harmonizing the drugs. The traditional Chinese medicine composition disclosed by the invention can be used for preventing and treating cognitive disorder, mood disorder and depressive state caused by metabolic disorder. The traditional Chinese medicine composition is small in side effect, high in individuation and suitable for being taken for a long time, and has an obvious treatment effect.
Owner:NINGXIA MEDICAL UNIV

Traditional Chinese medicine composition for treating chronic atrophic gastritis and preparation method and application thereof

The invention belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating chronic atrophic gastritis and a preparation method and application thereof. According to the technical scheme, the traditional Chinese medicine composition is characterized by being prepared from, by weight, 10-50 parts of radix codonopsis, 5-20 parts of roasted rhizoma atractylodis macrocephalae, 5-10 parts of rhizoma pinellinae praeparata, 2-8 parts of rhizoma coptidis, 8-40 parts of poria cocos, 5-15 parts of radix salviae miltiorrhizae, 3-6 parts of rhizoma zingiberis, 5-15 parts of rhizoma cyperi, 1-20 parts of radix actinidiae chinensis and 1-5 parts of radix glycyrrhizae preparata. The traditional Chinese medicine composition provided by the invention can improve the pathological morphology of stomach tissues, increase the expression of PG I and the ratio of PG I to PG II, reduce the level of inflammatory factors and improve the atrophy degree of gastric mucosa, and is used for treating stomachache, distention and fullness, anorexia, gastric noisy and other symptoms caused by spleen and stomach qi deficiency, qi stagnation and blood stasis and damp-toxin interjunction of patients with chronic atrophic gastritis.
Owner:GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI

Sand removing and cleaning device for coptis chinensis

The utility model discloses a coptis chinensis sand removing and cleaning device, which belongs to the technical field of coptis chinensis cleaning and comprises a box body, a partition plate is fixedly connected to the inner wall of the box body, a plurality of first through holes are formed in the surface of the partition plate, and a first conveying assembly is arranged on the inner wall of the box body. The first conveying assembly comprises two first rotating shafts, two transmission wheels, a transmission belt, a plurality of shifting nets and a first motor, a second conveying assembly is arranged on the inner wall of the box body, the box body is arranged, so that rhizoma coptidis is conveniently soaked, silt conveniently flows into the box body under the action of a partition plate and a first through hole, and the first conveying assembly and the second conveying assembly are arranged; and water flow drives silt to be discharged through a sewage draining opening, the water flow is kept at a certain cleanliness, the cleaning effect is improved, a first conveying assembly is arranged, so that a plurality of transmission belts conveniently drive a shifting net to move, and the soaked coptis chinensis is conveniently pushed to move.
Owner:HENAN HUAXIA MEDICINAL MATERIALS CO LTD

Composite plant polypeptide composition with functions of repairing pancreas and reducing blood sugar

The invention discloses a composite plant polypeptide composition with the effects of repairing pancreas and reducing blood sugar. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10 to 50 parts of ginsenoside, 5 to 30 parts of radix astragali seu hedysari extract, 3 to 20 parts of radix rehmanniae polysaccharide, 2 to 15 parts of radix trichosanthis alkaloid, 5 to 25 parts of rhizoma dioscoreae polysaccharide, 5 to 30 parts of bitter gourd polypeptide, 3 to 20 parts of folium mori alkaloid, 8 to 40 parts of rhizoma polygonati polysaccharide, 5 to 25 parts of fructus hippophae flavone, 10 to 35 parts of wheat germ peptide, 2 to 15 parts of coptis berberine, 10 to 45 parts of corn stigma polysaccharide and 3 to 20 parts of saussurea involucrata polyphenol. 1-10 parts of sophora flavescens total alkaloids, 5-25 parts of a dendrobium extract, 5-30 parts of a radix puerariae extract, 8-35 parts of L-arabinose and 10-40 parts of small molecule peptides; 20 to 100 parts of collagen peptide and 15 to 80 parts of albumin peptide; 5-50 parts of microcrystalline cellulose, 3-30 parts of fructo-oligosaccharide and 0.5-5 parts of magnesium stearate; the limitation of single sugar control or simple component mixing in the prior art is broken through, a synergistic system of plant active components and functional polypeptides is constructed, and the purity and retention rate of the plant active components are improved by optimizing the extraction process.
Owner:孟云富

Flavor-modifying preparation method of Wanchu granules

InactiveCN119909023AAntipyreticHydroxy compound active ingredientsBiotechnologyPicrorhiza scrophulariiflora
The invention discloses a flavoring preparation method of Wanchu granules, and belongs to the field of medicine preparation, and the flavoring preparation method comprises the following steps: S1, forming first mixed powder from rhizoma picrorhizae, rhizoma coptidis, catechu and fragrant ink; s2, in-vitro cultured calculus bovis is mixed with the first mixed powder to form second mixed powder; s3, forming bear gall powder liquid; s4, forming ox gall paste; s5, forming a third mixture from the ox gall paste and the bear gall powder liquid; s6, mixing the rape flower honey filtrate, the second mixed powder and the third mixture, granulating through a granulator, drying and finishing; and S7, mixing the borneol and artificial musk particles obtained in the step S6. According to the invention, not only is the taste modifying effect of the Wanchu granules greatly improved, but also the heat clearing effect of the Wanchu granules is improved.
Owner:CHENGDU YANGTIAN WANYING PHARM CO LTD

Mongolian medicine composition for treating hepatitis B and preparation method thereof

The invention provides a Mongolian medicine composition for treating hepatitis B and a preparation method of the Mongolian medicine composition. The composition is prepared from the following components in parts by weight: 75 to 85 parts of saffron, 75 to 85 parts of trogopterus dung, 65 to 75 parts of gardenia jasminoides, 45 to 55 parts of cortex phellodendri, 45 to 55 parts of dianthus chinensis, 55 to 65 parts of gypsum, 55 to 65 parts of scabiosa, 55 to 65 parts of calamine, 55 to 65 parts of caulis akebiae, 25 to 35 parts of rhizoma coptidis, 25 to 35 parts of fructus gardeniae, 25 to 35 parts of calomel, 25 to 35 parts of bunge corydalis herb, 45 to 55 parts of elecampane, 45 to 55 parts of rose and 55 to 65 parts of calculus bovis factitius. The Mongolian medicine composition for treating hepatitis B is prepared from multiple raw materials, meanwhile, the added coptis chinensis and rose flowers are treated through a specific extraction mode and a specific fermentation mode, and the prepared Mongolian medicine composition for treating hepatitis B has an excellent hepatitis B treatment effect.
Owner:KORQIN RIGHT WING ZHONGQI WANGBUHE MENGYI HOSPITAL CO LTD

Traditional Chinese medicine composition for reducing blood pressure and preventing heart diseases

The invention discloses a traditional Chinese medicine composition for reducing blood pressure and preventing heart diseases, and belongs to the technical field of traditional Chinese medicine preparation, and the traditional Chinese medicine composition is prepared from the following raw materials: selfheal, radix puerariae, eucommia ulmoides, salvia miltiorrhiza, ligusticum wallichii, radix paeoniae rubra, fructus trichosanthis, coptis chinensis, semen cassiae, angelica sinensis, radix paeoniae alba, rhizoma polygonati, dogwood, rhizoma atractylodis macrocephalae, poria cocos, radix cyathulae, radix curcumae, hawthorn and rheum officinale. The traditional Chinese medicine composition is suitable for people suffering from hypertension in the early stage, the middle stage and the later stage, has a good multi-target-point, targeted and broad-spectrum blood pressure lowering effect and a defecation effect, and can also protect the heart function, so that the risk of cardiovascular and cerebrovascular disease complications caused by hypertension lesion is reduced.
Owner:李广东

Anti-alcohol composition as well as preparation method and application thereof

The invention discloses a hangover alleviating composition and a preparation method and application thereof, and belongs to the technical field of hangover alleviating, the hangover alleviating composition is prepared by taking hovenia acerba flavone, pueraria flavone and mulberry polysaccharide as functional components and taking chaff fruit polysaccharide as a synergist, the hovenia acerba flavone, pueraria flavone and mulberry polysaccharide play a hangover alleviating effect, and the hangover alleviating effect is achieved. The chaff fruit polysaccharide is used for synergism, so that the sobering time is greatly shortened, and the sobering effect is improved.
Owner:PINGDINGSHAN UNIVERSITY

Cell active peptide composition for resisting acnes and regulating skin micro-ecology, preparation method of cell active peptide composition and application of cell active peptide composition in medicine and beauty

InactiveCN119074893ARemoval of keratinizationRegulating MicroecologyOrganic active ingredientsCosmetic preparationsDipeptidePolylysine
The invention relates to a cell active peptide composition for resisting acnes and regulating skin micro-ecology, a preparation method thereof and application of the cell active peptide composition in medicine and beauty, and belongs to the technical field of medicine and beauty. The composition disclosed by the invention is prepared from a rhizoma coptidis extract, hydrolyzed zinc hyaluronate, azelaic acid, nisin, polylysine, palmitoyl tripeptide-8, palmitoyl tripeptide-5, dipeptide-15, capryloyl glycine, a lactobacillus fermentation extract and a bifidus yeast fermentation product lysate. The composition can balance peripheral androgen and reduce excessive secretion of sebum; hair follicle keratinization is removed, and pores are dredged; pathogenic bacterium infection is inhibited; acne injuries such as acne pits, acne marks, scars and pigmentation are repaired; the skin micro-ecology is balanced; the pores are shrunk. The composition is applied to skin beauty and skin medicine to effectively reduce the oil spot area, the oil intensity, the acne volume and the acne a value, and has the effects of resisting acnes and regulating the skin micro-ecology.
Owner:ZHUHAI GOLDEN PEPTIDE BIOTECHNOLOGY CO LTD +1

Composition for regulating scalp micro-ecology and application thereof

The invention discloses a composition for regulating scalp micro-ecology, which comprises a component A and a component B, the component A is prepared from the following components in parts by weight: 5 to 15 parts of amur corktree bark extract, 3 to 14 parts of rhizoma coptidis root extract, 5 to 15 parts of radix sophorae flavescentis extract, 2 to 8 parts of rhus chinensis insect gall extract, 2 to 18 parts of fructus cnidii extract, 3 to 10 parts of pericarpium zanthoxyli extract, 1 to 5 parts of camphor tree root extract, 3 to 12 parts of ginger root extract, 5 to 15 parts of radix polygoni multiflori extract and 5 to 25 parts of swertia japonica extract; 10-30 parts of a Chinese arborvitae twig and leaf extract; the component B is prepared from the following components in parts by weight: 70 to 90 parts of cocamidopropyl-PG-sodium dimethyl ammonium chloride phosphate, 10 to 30 parts of sodium isostearoyl lactylate and 1 to 10 parts of dichlorobenzyl alcohol; the weight ratio of the component A to the component B is 10: 1. The composition can effectively regulate scalp micro-ecological balance, remarkably inhibit overgrowth and reproduction of common harmful bacteria on scalp, protect or moderately promote growth of beneficial bacteria on scalp, maintain healthy flora structure and diversity, fundamentally improve scalp health by recovering and maintaining the balance state of scalp micro-ecology, and improve scalp quality. The shampoo has multiple good effects of controlling oil, preventing alopecia, relieving itching and removing dandruff.
Owner:GUANGDONG DIMEI NEW MATERIAL TECH CO LTD

Traditional Chinese medicine composition for treating diabetic kidney disease as well as pharmaceutical preparation and application of traditional Chinese medicine composition

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating diabetic kidney diseases and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 10 to 60 parts of raw radix astragali seu hedysari, 5 to 30 parts of rhizoma polygonati, 5 to 30 parts of rhizoma dioscoreae, 5 to 30 parts of fructus corni, 3 to 15 parts of rhizoma coptidis, 5 to 30 parts of ramuli euonymi, 5 to 30 parts of fructus arctii and 3 to 15 parts of leech. The traditional Chinese medicine composition preferably selects the raw material medicines and compatibility thereof, focuses on strengthening spleen and middle warmer, tonifying spleen and kidney, strengthening spleen and reinforcing kidney, clearing heat and removing toxicity, gives full play to the treatment characteristics of multi-component, multi-path and multi-target synergistic effect of traditional Chinese medicines, and can obviously improve clinical healing of patients with diabetic kidney diseases. The early-stage small-scale clinical observation shows that the prescription for invigorating spleen, tonifying kidney, clearing heat and harmonizing collaterals can effectively improve clinical symptoms and traditional Chinese medicine syndromes of patients with diabetic kidney diseases, reduces UACR values, and has good popularization and application values.
Owner:SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M

Application of rhizoma coptidis alkaloid in preparation of medicine for down-regulating liver TREM2 expression

The invention relates to application of coptis alkaloid in preparation of a medicine for down-regulating liver TREM2 expression, and belongs to the technical field of biological medicine. Animal experiments prove that the rhizoma coptidis alkaloid has the effects of improving liver pathological injury, lipid droplet deposition, liver function impairment, fatty degeneration, iron overload and inflammatory response caused by MASH, and meanwhile, the expression level of TREM2 is improved.
Owner:GUANGZHOU UNIVERSITY OF CHINESE MEDICINE

Hypoglycemic traditional Chinese medicine composition for inhibiting metabolic inflammation and preparation method of hypoglycemic traditional Chinese medicine composition

The invention discloses a blood-glucose-reducing traditional Chinese medicine composition for inhibiting metabolic inflammation and a preparation method of the blood-glucose-reducing traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20-40 parts of herba eupatorii, 5-7 parts of rhizoma coptidis, 10-20 parts of ginseng, 10-20 parts of poria cocos, 10-20 parts of roasted rhizoma atractylodis macrocephalae, 5-7 parts of honey-fried licorice root, 10-20 parts of agastache rugosus, 8-10 parts of radix aucklandiae, 12-22 parts of radix puerariae, 8-10 parts of stiff silkworm, 10-20 parts of ramulus euonymi, 10-20 parts of ramulus mori and 2-5 parts of cortex cinnamomi. The traditional Chinese medicine composition disclosed by the invention can be used for inhibiting the proinflammatory factor IL-6 level (Plt; 0.05), increasing the level of anti-inflammatory factor IL-22 (Plt; in small intestine tissues of rats with type 2 diabetes, the traditional Chinese medicine composition disclosed by the invention can be used for relieving inflammation infiltration; immunohistochemical detection results show that the traditional Chinese medicine composition can improve the expression level of AHR and IL-22 in small intestine tissues, provides a scientific basis for inhibiting metabolic inflammation by using a detoxification and turbidity dissolving method so as to improve insulin resistance and treat type 2 diabetes, and also provides a new treatment idea and drug selection.
Owner:GUIYANG COLLEGE OF TRADITIONAL CHINESE MEDICINE

Traditional Chinese medicine composition and patch for treating tourette syndrome of children

The invention relates to a traditional Chinese medicine composition and patch for treating tourette syndrome of children, and belongs to the technical field of traditional Chinese medicine compositions.The traditional Chinese medicine composition is prepared from calcined oyster shell, semen boitae, radix bupleuri, rhizoma gastrodiae, radix paeoniae alba, rhizoma curcumae longae, periostracum cicada, honey-fried licorice root, rhizoma zingiberis, szechwan chinaberry fruit, rhizoma coptidis, fructus evodiae, uncaria and the like. The preparation method of the patch provided by the invention comprises the following steps: mixing radix bupleuri, uncaria rhynchophylla and the like, and performing alcohol extraction to obtain an alcohol extraction extract; performing water extraction on platycladi seeds, gastrodia elata and the like to obtain water extract; mixing the calcined oyster shell powder, the alcohol extract, the water extract and the hydrogel matrix to obtain a medicine carrying layer; the medicine carrying layer and the permeation enhancing layer are attached, and the patch is obtained after plastic packaging. The composition disclosed by the invention is reasonable in compatibility, has a good treatment effect on the tourette syndrome of children, and is stable in curative effect and good in transdermal absorption efficiency.
Owner:GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI

Coptis transplanter missing planting detection and compensation system and method based on multi-sensor fusion

The invention discloses a rhizoma coptidis transplanter miss-planting detection and compensation system and method based on multi-sensor fusion, the system comprises a sensing layer, a control layer and an execution layer, the sensing layer is used for collecting multi-source planting data of each planting period of a rhizoma coptidis transplanter; the control layer is used for processing the multi-source planting data collected by the sensing layer in each planting period, calculating a planting state estimation value of the current planting period after each planting period is finished, and judging whether the current planting period is planting missing or not; and the execution layer is used for controlling the coptis transplanter to return to the missing planting point to execute complementary planting operation after the control layer judges that the current planting period is missing planting. The method is implemented based on the system. The method has the advantages that the problems that a traditional instantaneous signal detection method is poor in reliability and high in misjudgment rate in a complex farmland environment are fundamentally solved, and therefore high-reliability missing planting detection and accurate automatic compensation are achieved.
Owner:WUHAN VOCATIONAL COLLEGE OF SOFTWARE & ENG (WUHAN OPEN UNIV)

Detoxifying and stasis-removing traditional Chinese medicine composition, capsule and preparation method thereof

The invention discloses a detoxifying and stasis-removing traditional Chinese medicine composition, a capsule and a preparation method thereof. The traditional Chinese medicine composition for detoxifying and removing stasis is prepared from the following raw materials in parts by mass: 285 to 315 parts of radix scutellariae, 185 to 215 parts of rhizoma coptidis, 185 to 215 parts of radix sophorae flavescentis, 225 to 255 parts of fructus forsythiae, 225 to 255 parts of radix salviae miltiorrhizae, 185 to 215 parts of rhizoma polygoni cuspidati, 285 to 315 parts of herba artemisiae scopariae and 185 to 215 parts of pericarpium citri reticulatae. The traditional Chinese medicine composition has the major functions of clearing heat and drying dampness, purging fire and removing toxin, and activating blood and removing stasis. The traditional Chinese medicine is suitable for acne vulgaris (excessive heat in lung and stomach and damp-heat in stomach and intestine). Particularly, the skin lesion degree, the number of inflammatory skin lesions, the skin lesion color, the smooth and bright face and other symptoms are obviously improved.
Owner:BEIJING LINGRUI WEIYE TECH CO LTD +1

Traditional Chinese medicine compound extract for repairing oral mucosa, extraction method of traditional Chinese medicine compound extract, oral mucosa repairing preparation and preparation method of oral mucosa repairing preparation

The invention relates to the technical field of traditional Chinese medicine extraction and preparation, in particular to a traditional Chinese medicine compound extract for repairing oral mucosa, an extraction method of the traditional Chinese medicine compound extract, an oral mucosa repairing preparation and a preparation method of the oral mucosa repairing preparation. The traditional Chinese medicine compound extract is prepared from 4.8% of radix scutellariae, 4.3% of cortex phellodendri, 4.0% of radix notoginseng, 4.5% of rhizoma coptidis, 4.4% of indigo naturalis, 4.3% of nacre mother of pearl, 25.0% of radix arnebiae seu lithospermi, 4.3% of fructus cnidii, 35.6% of aloe, 4.3% of cortex magnoliae officinalis, 4.3% of dandelion, 0.1% of borneol and 0.1% of camphor, natural Chinese herbal medicine ingredients are adopted, side effects of chemical drugs are reduced, adverse reactions possibly caused by long-term use of hormone drugs are avoided, the traditional Chinese medicine compound extract is suitable for long-term use, and the traditional Chinese medicine compound extract is free of toxic and side effects. The heavy metal content is strictly controlled to ensure that the product safety reaches the standard required by the drug administration department.
Owner:SICHUAN UNIV

Thin-layer chromatography method for identifying radix angelicae lateralis preparata component in rhizoma coptidis paste and application of thin-layer chromatography method

The invention relates to the technical field of traditional Chinese medicine detection, and particularly discloses a thin-layer chromatography method for identifying radix angelicae lateralis preparata components in rhizoma coptidis paste and application of the thin-layer chromatography method. The thin-layer chromatography method provided by the invention comprises the following steps: preparing a test solution: adding methanol water into coptis chinensis paste, heating and melting, and then refluxing and stirring; storing at 0 + / -5 DEG C; then, dichloromethane-n-butyl alcohol with the volume ratio of (2.5-3.5): 1 is adopted as an eluent, silica gel column filtration is performed to obtain a filtrate, and the filtrate is evaporated to dryness and dissolved to obtain a test solution; preparing a reference solution; and detection: respectively dripping the solutions on the same silica gel G thin-layer plate, putting the silica gel G thin-layer plate into a developing cylinder to be developed by taking ethyl acetate-isopropanol with the volume ratio of (3-5): 1 as a developing solvent, and inspecting under a light source of 360-370nm. The thin-layer chromatography method provided by the invention can be used for rapidly and accurately identifying the radix angelicae lateralis preparata component in the rhizoma coptidis paste, and a theoretical basis is provided for quality control of the rhizoma coptidis paste.
Owner:SHANTOU MEBO PHARMA CO LTD

Slow-release composition for solving ruminant rumen acidosis as well as preparation method and application thereof

The invention relates to the technical field of feed additives, in particular to a sustained-release composition for solving ruminant rumen acidosis as well as a preparation method and application of the sustained-release composition. The composition is prepared from the following components in parts by weight: 30 to 60 parts of complex microbial inoculant capsules, 10 to 30 parts of thiamine, 5 to 15 parts of light calcium carbonate, 5 to 15 parts of magnesium oxide, 8 to 18 parts of sodium bicarbonate, 2 to 5 parts of rare earth elements, 3 to 8 parts of rhizoma coptidis, 5 to 15 parts of rhizoma atractylodis macrocephalae, 4 to 9 parts of poria cocos and 2 to 5 parts of rhizoma corydalis. The complex microbial inoculant capsule at least comprises parabacteroides dieldrii, bacillus subtilis, bacillus licheniformis, enterococcus faecalis and lactobacillus rosenbergii; the rare earth element is a mixture of lanthanum nitrate and cerous nitrate, and the mass ratio of lanthanum nitrate to cerous nitrate is 1: 1. The composition can be used for preventing and treating ruminant rumen acidosis, can be slowly released in the stomach due to the slow release effect, and does not need to be used as a feed additive all the time.
Owner:CHENGDU ZHONGKE LIYUAN BIOTECHNOLOGY CO LTD +2

Traditional Chinese medicine probiotic composition for improving type 2 diabetes mellitus as well as preparation method and application of traditional Chinese medicine probiotic composition

The invention belongs to the technical field of pharmaceutical compositions, and discloses a traditional Chinese medicine probiotic composition for improving type 2 diabetes and a preparation method and application thereof. The composition is obtained by fermenting a traditional Chinese medicine composition with a compound probiotic liquid, wherein traditional Chinese medicine components in the traditional Chinese medicine composition liquid comprise, by weight, 5-10 parts of radix puerariae, 2-3 parts of honey-fried licorice roots, 3-4 parts of radix scutellariae and 3-4 parts of coptis chinensis, and the composite probiotic liquid is obtained by mixing a lactobacillus plantarum liquid and a pediococcus pentosaceus liquid according to the volume ratio of (0.3-3): 1. The traditional Chinese medicine probiotic composition provided by the invention contains probiotics (lactobacillus and the like), and the intervention of the radix puerariae, the rhizoma coptidis, the radix scutellariae and the liquorice can promote the growth of intestinal probiotics, regulate the alteration of intestinal flora and improve the clinical treatment effect of patients with type 2 diabetes mellitus.
Owner:XIHUA UNIV

Coptis processing, desliming and drying equipment and using method thereof

The invention relates to the technical field of rhizoma coptidis processing, in particular to rhizoma coptidis processing, desliming and drying equipment and a use method of the rhizoma coptidis processing, desliming and drying equipment. The processing assembly comprises a support, a first moving unit, a collecting unit, a belt conveyor, two lifting rotating units, a plurality of cleaning brushes, a second moving unit, a cleaning box, a first heating plate, a stirring unit, a water inlet unit and a drainage pump, and the lifting rotating units drive the cleaning brushes to move downwards and rotate to clean soil on coptis chinensis; after the collecting unit is full, the first moving unit drives the collecting unit to move to the position above the belt conveyor; the coptis chinensis is gradually put on a belt conveyor, and then secondary cleaning is conducted; the second moving unit drives the cleaning box to move below the stirring unit and the water inlet unit; the water inlet unit adds water into the cleaning box, meanwhile, the stirring unit conducts slow stirring, coptis chinensis is washed, soil is cleaned away, and therefore stubborn soil attached to coptis chinensis rhizomes can be effectively cleaned.
Owner:SHIZHU TUJIA AUTONOMOUS COUNTY HUAWEI HUANGLIAN PURCHASE & SALES CO LTD

Chinese wolfberry fruit compound fermentation liquor as well as preparation method and application thereof

The invention relates to fructus lycii compound fermentation liquor as well as a preparation method and application thereof, and belongs to the technical field of fermentation. According to the preparation method, fructus lycii, rhizoma coptidis, radix notoginseng, radix astragali seu hedysari, rhizoma bletillae, fructus chebulae and rhizoma dioscoreae are mixed and subjected to high-temperature extraction, ackermania muciniphila ATCC BAA-835 is utilized for primary fermentation, lactobacillus paracasei is utilized for secondary fermentation, and the obtained compound fermentation liquor has the advantages that the effect of improving the anti-inflammatory effect is achieved in a complex DSS + bound stress compound type inflammatory bowel disease injury model; according to the invention, all-around protection effect is shown, the efficacy of the lactobacillus plantarum is obviously better than that of unfermented raw materials, any single strain fermented product and a contrast product fermented by adopting strains reported in literature in the same proportion, and important technical support and product prototype are provided for developing functional food for inflammatory bowel diseases and related neuropsychiatric diseases.
Owner:JIANGNAN UNIV