470results about How to "Improve efficacy" patented technology

The invention provides a compound probiotic and qi and blood tonifying fermentation composition and a preparation method and application thereof, and relates to the technical field of microorganisms, the compound probiotic comprises plant lactobacillus KMHD-1 and bifidobacterium longum KMBGI 01, the compound probiotic is adopted for fermentation, the fermentation composition capable of tonifying qi and blood, improving immunity and improving energy can be prepared, and the preparation method is simple and convenient. And the compound probiotics are adopted to ferment the fermentation substrate, so that the variety and content of rare ginsenoside of ginseng can be effectively increased, the content of astragaloside and polysaccharide can be increased, and the efficacy of the product is further enhanced.

The invention is about a method of marking ink which is only used to defend fake. The composition of it is: lipidol or lipid, surface active agent, integration agent, water, buffering agent. Their mass percents are: 1,2-hexylene glycol: 5%-15%, butanol: 1-5%, DH-1: 5-10%, EDTA: 0.1-0.5%, MS-1: 0.1-1%, water: the rest. The process is: a. dissolving the colorant in water, b. put the correct percent of 1,2-hexylene glycol and butanol into the solvent, then dropping the MS-1 and EDTA solution when mixing the solvent for 30-50 min, c. put the rest precent of water into the printing ink box. The picture and word would be shown red fluorescence in the UV but blank in the usual light.

The invention discloses a method for immobilizing growth-promoting rhizobacteria by taking decarburized gangue-based biochar as a carrier, a solid waste-based microorganism immobilization ball prepared by the method and application of the solid waste-based microorganism immobilization ball, and relates to the technical field of solid waste utilization. The method comprises the following steps: preparing gangue-based zeolite by microwave activation and decarburization of coal gangue; preparing gangue-based biochar by utilizing phosphorus modification; and preparing the solid-waste-based microorganism solidification balls by utilizing an adsorption-embedding-crosslinking method. The decarburized gangue-based biochar is used as a carrier material for immobilizing the growth-promoting rhizosphere bacteria, and is used for restoring the sandy degraded soil in the northwest arid mining area. According to the technology, the survival time and functional activity of the growth-promoting rhizobacteria in the soil environment can be improved, and a new way is provided for consumption of bulk gangue solid waste. The method also has the technical advantages of improving the carbon source utilization rate of the gangue and increasing the phosphate fertilizer and the organic carbon library of the soil.

The invention provides a preparation method and application of magnesium L-threonate, and belongs to the technical field of medicines. The preparation method comprises the following steps: dissolving L-ascorbic acid in water, adding magnesium hydroxide and alkaline magnesium carbonate, stirring, dropwise adding hydrogen peroxide, heating, stirring and reacting, filtering a product, purifying and concentrating by temperature-sensitive molecularly imprinted hydrogel while the product is hot, adding an ethanol water solution into a concentrated solution, standing, crystallizing, filtering, washing and drying to obtain the magnesium L-threonate. And cooling the temperature-sensitive molecularly imprinted hydrogel after adsorption to room temperature, washing and repeatedly using the temperature-sensitive molecularly imprinted hydrogel. The magnesium L-threonate is simple in preparation method, high in purity and high in yield, meanwhile, the slow-release magnesium L-threonate is prepared, and the magnesium L-threonate is low in toxicity, good in biocompatibility, large in drug loading capacity, low in economic cost and good in drug effect and has wide application prospects in preparation of anti-depression drugs.

The invention belongs to the technical field of medicines, and provides application of Nintedanib and a plant-derived cyclic peptide and radix pseudostellariae cyclic peptide B combined medicine in preparation of a medicine for treating pulmonary fibrosis, the Nintedanib and the plant-derived cyclic peptide and radix pseudostellariae cyclic peptide B combined medicine can play a synergistic effect, and the inhibition effect on the pulmonary fibrosis process is remarkably improved. The toxic and side effects of diarrhea and intestinal mucosa injury caused by nintedanib are reduced, and a good choice is provided for clinical treatment of pulmonary fibrosis.

The invention relates to a fluxazole amide composition and a preparation method thereof. More specifically, the present invention relates to synergistic compositions of fluoxazole amides and methods of preparing stable and non-phytotoxic formulations, the synergistic composition comprises fluoxazole amide or an agrochemically acceptable salt thereof, an insecticide selected from diamides, at least one or more compounds selected from insecticides, fungicides and plant health additives, and an agrochemically acceptable excipient. The invention further relates to pesticidal compositions for controlling harmful pests in plants, which can be formulated, are environmentally safe, exhibit high efficacy, and act on disease resistance management or delay the development of disease resistance by employing a variety of modes of action, plant tolerance against insect pests, mites, fungal and bacterial diseases and abiotic stress is increased and the overall health and vigor of the treated plant is improved.

The invention provides an immunogenicity prediction method and device based on multimode fusion and a storage medium. The method comprises the following steps: constructing a multimode prediction model; obtaining each data set; correspondingly training a multi-modal prediction model based on each data set to obtain a trained multi-modal prediction model; fusing the trained multi-modal prediction models, and constructing an immunogenicity comprehensive evaluation model; forming an intelligent immunogenicity prediction system based on the trained multi-modal prediction model and the immunogenicity comprehensive evaluation model; and performing immunogenicity prediction on the to-be-predicted protein based on the immunogenicity prediction intelligent system to obtain a test result, the test result comprising the immunogenicity risk score of the to-be-predicted protein and the potential immunogenicity T cell epitope on the to-be-predicted protein. According to the method, the effect of directionally optimizing the immunogenicity on the basis of the prediction result can be achieved, and the drug effect and safety of protein biological drugs can be improved.

The invention belongs to the technical field of cosmetic raw materials, and particularly provides a composition containing kava pepper and mung bean seed extracts, a preparation method and application. The preparation method of the mung bean seed extract is specifically optimized, for example, a lactobacillus plantarum strain, a lactobacillus johnsonii strain and a lactobacillus acidophilus strain are compounded and used for fermenting sprouted mung bean liquid, and a fermentation culture medium, fermentation environment conditions and the like are optimized; the nutritional ingredients of protein, glycine, inorganic salt and the like in the prepared mung bean seed extract are effectively improved, so that the prepared composition containing the kava pepper and the mung bean seed extract and the cosmetics thereof can show excellent effects of moisturizing and repairing, resisting inflammation, resisting aging, instantly calming, easing pain and the like.

The invention discloses a preparation process and application of magnolol-loaded plant exosomes, and relates to the technical field of plant exosomes. Magnolol is extracted from a magnolia officinalis plant material through ultrasonic assistance, the plant exosomes are obtained from fresh ginger by using an ultracentrifugation method, and the plant exosomes are further modified through palmitic acid and polyethylene glycol, so that the magnolol-loaded plant exosomes are obtained. And finally, preparing the magnolol-loaded plant exosome by virtue of an incubation method. The magnolol can be protected from being damaged by gastric acid and digestive enzymes through membrane structure wrapping of the plant exosome, the stability of the magnolol in the digestive tract is improved, and it is further verified through mouse experiments that the magnolol-loaded plant exosome can be beneficial to regulation of intestinal flora.

The invention provides a preparation method of 11-seed fermentation oil and fermentation liquor with multiple effects, and belongs to the technical field of fermentation. The method comprises the following steps: S1, preparing recombinant saccharomycetes; s2, jointly fermenting lactobacillus, recombinant saccharomycetes and 11 seed oil; s3, separating an oil phase and a water phase, and taking the oil phase; and S4, dehydrating the oil phase to obtain the 11-seed fermentation oil. And S5, further refining the water phase to obtain the 11-seed fermentation liquor. The 11-seed fermented oil prepared by transforming a microbial metabolic network is rich in dihydroquercetin, and has multiple effects of resisting oxidation, resisting wrinkles, tightening, repairing cells and the like. In the fermentation process of the 11-seed fermentation oil, 11-seed fermentation liquor can be obtained, and the fermentation liquor has multiple effects of resisting oxidation, relieving, moisturizing, resisting wrinkles, tightening and the like.

The present invention belongs to the field of medical technology related to the extraction and application of natural drug components, discloses a white peony extract for treating hyperuricemia, a preparation method thereof and an application thereof, and provides a preparation method of a white peony extract for treating hyperuricemia, wherein the obtained white peony extract has a good therapeutic effect on a hyperuricemia animal model; mainly inhibiting uric acid production by inhibiting the activity of xanthine oxidase in serum and liver, while downregulating the levels of renal tissue proteins URAT1 and GLUT9, and upregulating the levels of renal tissue proteins OAT1 and OAT3 to reduce uric acid reabsorption and promote uric acid excretion, thereby achieving the purpose of reducing uric acid levels. Furthermore, the white peony extract is synergistically used with the currently commonly used uric acid-lowering drug allopurinol to develop a more effective and safe uric acid-lowering treatment plan.

The present invention proposes a Chinese medicine composition for treating allergic rhinitis, and a preparation method and application thereof, which belong to the field of pharmaceutical technology. Ag-graphene oxide is adsorbed on in vitro proliferated γδT cells, a Chinese medicine fermentation product obtained by fermentation and extraction of Xanthium sibiricum, Astragalus, Poria, Magnolia officinalis, and Mentha is prepared, berberine and quercetin are prepared into eutectic powder, the three are mixed and added into water, probiotics, carboxymethyl chitosan, poloxamer 407 and poloxamer 188 are added, and mixed evenly to prepare a Chinese medicine composition for treating allergic rhinitis, which has a good effect of improving allergic rhinitis, adopts a method of combining traditional Chinese and Western medicine, reduces inflammatory response, enhances the immune function of patients, improves the clinical symptoms of patients with allergic rhinitis, reduces the long-term recurrence rate, reduces the use of drugs, improves the quality of life, and reduces the risk of developing asthma, and has broad application prospects.

The invention relates to a preparation method of a white tea fermentation product with moisturizing, anti-aging and soothing effects as well as a product and application thereof. The preparation method comprises the following steps: mixing dry white tea leaves with water, soaking, and then carrying out heat extraction and solid-liquid separation to obtain a white tea extracting solution; inoculating the sterilized culture medium containing the white tea extracting solution with compound lactobacillus, and performing primary fermentation to obtain a primary fermentation product; mixing the primary fermentation product, a sorghum rice extract and a Chinese wolfberry fruit extract, performing sterilization treatment, inoculating compound yeast, and performing secondary fermentation to obtain a secondary fermentation product; and sterilizing the secondary fermentation product, cooling, and carrying out solid-liquid separation to obtain the white tea fermentation product. The preparation method of the white tea fermentation product is simple in process, industrial production is easy to realize, and the prepared fermentation product is mild and non-irritant in component and high in safety, has excellent moisturizing, anti-aging and soothing effects, and can be used as a preparation raw material to be added into skin care products and cosmetics.

The invention relates to the field of functional food processing, and discloses a qi-tonifying and blood-activating dietary therapy formula based on the theory of qi and blood in traditional Chinese medicine, which comprises astragalus membranaceus, angelica sinensis, red dates, lycium barbarum, lycium ruthenicum, ginseng, salvia miltiorrhiza, mulberry, lucid ganoderma, cordyceps mycelium, rhodiola rosea, American ginseng, acanthopanax, grape seed extract and chrysanthemum. Through a compound formula based on the theory of qi and blood in traditional Chinese medicine, and by combining various core medicinal materials and functional plants such as the astragalus membranaceus, the angelica sinensis, the ginseng, the lucid ganoderma, the rhodiola rosea and the fructus lycii, the multi-level effects of tonifying qi, enriching blood, activating blood, resisting oxidation and regulating immunity are achieved. The technical effects of comprehensively regulating qi and blood and improving body immunity and resistance are achieved through the synergistic effect of the compound components, compared with a scheme of regulating qi and blood by depending on a single component in the prior art, the compound formula remarkably improves the overall drug effect, solves the problems that a single component is limited in regulating function and insufficient in curative effect, and is suitable for popularization and application. Therefore, the requirements of modern people on comprehensive conditioning and immunity enhancement are met.

The invention relates to the technical field of biology, in particular to a cytokine fusion protein and application thereof. The invention provides a cytokine fusion protein and application thereof. The expression problem of the membrane-bound IL-2 in NK cells is solved, and the membrane expression efficiency of the membrane-bound IL-2 is remarkably improved; according to the membrane binding IL-2 provided by the invention, the in-vivo drug effect and the in-vivo continuity of the CAR-NK are remarkably improved.

The invention discloses an ROS-responsive prostate cancer targeting prodrug as well as a preparation method and application thereof, and belongs to the technical field of biological medicines. The prodrug is formed by covalently linking a prostate cancer targeting peptide SYEELR, a ROS (reactive oxygen species) response type ketal thiol (TK) connexon and an active molecule Devimistat. The preparation method comprises the following two steps: firstly, coupling Devimistat with a TK linker to obtain an intermediate Dev-TK, and then coupling the intermediate Dev-TK with an SYEELR peptide fragment to obtain a target product. The prodrug can specifically break and release Devimistat in a tumor high active oxygen microenvironment, and active targeting delivery is realized by virtue of the SYEELR peptide. The invention provides a novel prostatic cancer treatment strategy with accurate targeting, controllable release, enhanced curative effect and toxicity reduction potential.

The present invention belongs to the technical field of skin care, and discloses a skin repair composition and a skin care product, wherein the skin repair composition comprises the following components by weight percentage: 30-50% wheat germ oil, 1-5% ceramide 3, 1-10% sodium hyaluronate, and 40-60% bifid yeast fermentation product lysate. The present invention utilizes bifid yeast fermentation product lysate to help restore the activity of fibroblasts and keratinocytes, repair cell damage and protect the components in the extracellular matrix ECM, and further strengthens the damage repair speed of ECM by compounding sodium hyaluronate and ceramide, helps cells and extracellular matrix maintain a healthy state and quickly repair damage, and helps strengthen intercellular lipids and cell adhesion at the same time, and finally helps form a good skin surface sebum film through the synergistic effect of wheat germ oil and sodium hyaluronate, and the four cooperate with each other to significantly improve the skin repair effect.

The invention provides an automatic high-speed unmanned aerial vehicle rocket boosting launching vehicle system. The automatic high-speed unmanned aerial vehicle rocket boosting launching vehicle system comprises an in-situ steering remote control electric lifting vehicle, a plurality of launching vehicle supporting leg assemblies, an inclined lifting launching support assembly, a launching front dumping support assembly, a rocket boosting launching support assembly, a braking ground pestle support assembly and a ground protection plate assembly. Compared with the prior art, the automatic high-speed unmanned aerial vehicle rocket boosting launching vehicle system can be switched between the folded state and the unfolded state, is flexible to use, high in reliability, high in environmental adaptability, wide in applicable aircraft type and rapid and safe to unfold and fold, and the shapes and positions of related devices can be designed in advance according to the model of an unmanned aerial vehicle so as to adapt to the unmanned aerial vehicle; man-machine efficiency is high, 1-2 persons can operate with light force, operation is easy, and the device can be widely used in the field of launching of unmanned aerial vehicles with rocket-assisted takeoff; and in addition, unmanned aerial vehicle transfer can be achieved with an operation frame of the high-speed unmanned aerial vehicle.

The invention discloses a lactobacillus rhamnosus composition for relieving gastrointestinal diarrhea and application of the lactobacillus rhamnosus composition, the composition is composed of a probiotic mixture, a prebiotic mixture and a carrier, the probiotic mixture is composed of lactobacillus plantarum JY055 bacterial powder, lactobacillus rhamnosus JM039 bacterial powder and lactobacillus rhamnosus JY027 bacterial powder, and the prebiotic mixture is composed of lactobacillus plantarum JY055 bacterial powder, lactobacillus rhamnosus JM039 bacterial powder and lactobacillus rhamnosus JY027 bacterial powder. The prebiotic mixture comprises inulin, xylitol, lactulose, resistant dextrin, a hawthorn extract and a dandelion extract, and the carrier is modified montmorillonite. The composition for relieving gastrointestinal diarrhea provided by the invention is composed of a mixture of three probiotics and prebiotics, and the probiotics are adhered to small intestinal mucosa epithelial cells to form a mycoderm and form an intestinal barrier, so that colonization and growth of harmful bacteria are prevented, self-protection of intestinal epithelial cells is enhanced, and the damaged intestinal barrier is repaired; the prebiotic mixture provides a breeding place and nutrient elements for growth and breeding of the probiotics, and the efficacy can be improved through mutual cooperation of the prebiotic mixture and the probiotics.

The invention discloses a Baoyuan decoction for relieving fatigue and regulating immunity and a preparation method thereof, and relates to the technical field of traditional Chinese medicine. The preparation method comprises: crushing ginseng, astragalus, licorice and cinnamon to obtain raw material A; mixing raw material A with extraction solvent 1, adding mixed enzyme, extracting, filtering to obtain extract 1 and filter residue 1; mixing filter residue 1 with water to obtain filter residue liquid, stirring and passing ozone treatment, filtering, washing, drying, and obtaining raw material B; mixing raw material B with extraction solvent 2, extracting, and combining extracts to obtain extract 2; mixing extract 1 and extract 2 uniformly, centrifuging, taking supernatant, adding water, and obtaining the Baoyuan decoction for relieving fatigue and regulating immunity. The present invention optimizes the extraction process, improves the efficacy, obtains better anti-fatigue effect and immunity improvement effect, and reduces the dosage of medication and improves patient compliance.

The invention relates to a composition for a pesticide, an insecticide and application of the insecticide, the composition comprises emamectin benzoate and a bamboo vinegar diluent, and the bamboo vinegar diluent is obtained by diluting bamboo vinegar with water. The insecticide comprises the composition for the pesticide, and the insecticide is applied to prevention and treatment of lepidoptera pests, mites, coleoptera pests and homoptera pests, especially to prevention and treatment of plutella xylostella. In the composition disclosed by the invention, the bamboo vinegar diluent is used as a synergist to improve the pesticide effect of the emamectin benzoate, so that the pesticide containing the composition can improve the effect of preventing and treating lepidoptera pests, mites, coleoptera pests and homoptera pests, particularly has a remarkable effect of preventing and treating plutella xylostella, and further has a remarkable effect of preventing and treating the emamectin benzoate. According to the insecticide, the dosage of the emamectin benzoate can be reduced, the drug resistance of pests can be overcome and delayed, and meanwhile, the risk levels of environmental pollution, pesticide residues and the like can be reduced.

The invention discloses an agkistrodon halys peptide composite probiotic solid beverage and a preparation method of the agkistrodon halys peptide composite probiotic solid beverage. Comprising the following raw materials in parts by weight: 12 to 17 parts of ginseng oligopeptide powder, 12 to 17 parts of soybean oligopeptide powder, 5 to 10 parts of agkistrodon halys peptide powder, 10 to 15 parts of ganoderan, 15 to 20 parts of fructo-oligosaccharide, 15 to 20 parts of glucose, 8 to 12 parts of cranberry powder, 0.5 to 1.5 parts of anhydrous citric acid, 5 to 10 parts of bifidobacterium bifidum BGN4, 7 to 13 parts of gamma-aminobutyric acid, 5 to 10 parts of yeast beta-glucan and 0.04 to 0.07 part of vitamin E. According to the solid beverage, various active peptides such as the agkistrodon halys peptide, the ginseng oligopeptide and the soybean oligopeptide are compounded with the probiotics and the dietary fibers, the bioavailability of all the components is improved, absorption of peptide substances can be promoted through the activity of the probiotics, and meanwhile the immunity of the organism can be remarkably enhanced through the synergistic effect of various functional components.

The invention discloses a mulberry linder hyphae tea bag with mulberry leaf and Fuzhuan tea as fermentation material and a preparation method thereof, and the preparation method steps are as follows: S1: activating the mulberry linder bevel mother species and inoculating it into a solid culture medium, and optimizing the quality under the stimulation of high and low concentration difference of inorganic selenium and the stress of mulberry leaf and Fuzhuan tea steaming extractant; S2: inoculating the mulberry linder hyphae mother species into a solid-liquid mixed fermentation agent culture medium for fermentation and culturing under the dual effects of low-solubility inorganic selenium stress and mulberry leaf and Fuzhuan tea golden flower fungus steaming extractant protection stimulation; S3: inoculating the mulberry linder solid-liquid mixed fermentation agent into the bagged pure mulberry leaf and Fuzhuan tea optimized fermentation material sterilized at high temperature under a sterile environment, and then moving it into a solid-state fermentation room for constant temperature, constant humidity and low carbon dioxide for culturing; S4: preparation of mulberry linder hyphae tea bag. The invention fundamentally solves the problems of bitter taste, poor taste, and difficulty in long-term storage in the existing mulberry leaf and Fuzhuan tea, and the prepared mulberry linder hyphae tea bag has better health care effect.

The invention discloses a natural plant anti-dandruff composition as well as a preparation method and application thereof, and relates to the technical field of daily necessities. The natural plant anti-dandruff composition comprises the following components: a chamaecyparis obtusa extract and a camellia seed cake extract, wherein the total mass of the natural plant anti-dandruff composition is 100%, the content of the chamaecyparis obtusa extract is 10-90%, and the content of the camellia seed cake extract is 10-90%. The raw materials of the natural plant anti-dandruff composition are natural and easy to obtain, the preparation method is green and safe, and the prepared composition has multiple effects of removing dandruff, controlling oil, relieving itching and the like, can effectively control dandruff, is friendly to scalp, does not irritate the scalp, is not prone to generating drug resistance, and has a good application prospect. The method has good efficacy, safety and practical feasibility.

The invention discloses a nicosulfuron-containing herbicidal composition and application thereof. The herbicidal composition is prepared from the following components: nicosulfuron, amicarbazone, and dimethyltetrachloroisooctyl ester as well as a dispersant, an emulsifier, a wetting agent, a thickening agent, an antifreeze, and a dispersion medium, wherein the dosage form belongs to a dispersed oil suspension agent. Through the combination of the three active ingredients, the herbicidal composition has an obvious synergistic effect, the use amount of pesticides is reduced, the cost and environmental pollution are reduced, the drug resistance of corn field weeds can be delayed by the application of the composition, and the control spectrum is expanded.

The invention relates to the technical field of pesticide preparations, and discloses a pesticide preparation containing Se-CDs, benzylaminopurine and triacontanol, the pesticide preparation is a nanometer suspending agent prepared from benzylaminopurine raw medicine, triacontanol raw medicine, a Se-CDs nanometer material and an auxiliary agent, and the particle size D90 of solid particles in the nanometer suspending agent is smaller than or equal to 800 nm; the auxiliary agent comprises a wetting dispersant, a thickening agent, a rheological agent, an anti-freezing agent, a preservative, a defoaming agent and deionized water, and the wetting dispersant is composed of an anionic-nonionic wetting dispersant SP-SC3219 and a weak cationic wetting dispersant SP-SC3275. According to the invention, the problems of large grinding particle size and long grinding time of a pesticide composition containing benzylaminopurine in the preparation and grinding process of a suspending agent and the problem of unstable fusion of Se-CDs with nano particle size and a suspending agent with micron particle size are solved, and the particle size stability and appearance stability of the preparation are improved.

The invention belongs to the technical field of pharmaceutical preparations, and relates to an oral solid pharmaceutical composition containing irbesartan and a preparation method thereof. Irbesartan particles are prepared by adopting a wet granulation process, levamlodipine besylate particles are prepared by adopting a dry granulation process, the irbesartan particles and the levamlodipine besylate particles are mixed, a filling agent adopted in the dry granulation process is microcrystalline cellulose, and the mass ratio of irbesartan to levamlodipine besylate is (150-300): (2-4). The content uniformity of the levamlodipine besylate can meet the standard, and the stability of the composition can be improved.

The invention discloses a hair loss prevention and hair growth composition, a preparation method thereof, and a hair care cosmetic containing the hair loss prevention and hair growth composition, which is composed of the following components: 1-2 parts of ginger root extract; 1-2 parts of Polygonum multiflorum extract; 2.58-8.3 parts of skin auxiliary conditioner; 0.56-2.1 parts of hair auxiliary conditioner; 0.1-2 parts of preservative; 5-15 parts of moisturizer; 70-85 parts of water. The above composition can effectively improve the hair microenvironment, inhibit sebum secretion, and prolong the hair survival cycle through the cooperation of the skin auxiliary conditioner and the ginger root extract. While comprehensively preventing hair loss, the hair auxiliary conditioner and the Polygonum multiflorum extract are used to regulate the blood supply of the key parts of the hair follicle cycle growth, enhance the vitality of the hair, and strengthen the hair roots, thereby achieving a comprehensive solution to various problems such as seborrheic alopecia, neurotic alopecia, diffuse alopecia, and nutritional alopecia.

The invention relates to a biotin receptor targeted photosensitizer or a pharmaceutically acceptable salt thereof, the biotin receptor targeted photosensitizer has a structure of the following general formula (I): # imgabs0 # (I), and a group R is a diamine derivative group of biotin and is defined in the specification. The invention further relates to preparation and application of the biotin receptor targeted photosensitizer and a medicine box containing the biotin receptor targeted photosensitizer.

The invention provides a preparation method and application of a skin care product rich in ergothioneine and nicotinamide, and belongs to the technical field of skin care products.According to the scheme, an ergothioneine solution is treated with a stabilizer, the pH value of a nicotinamide solution is adjusted, tea polyphenol is added, stability is improved, specific temperature, humidity and containers are specified in the storage link, and deterioration is prevented; ergothioneine and nicotinamide synergistically exert multiple effects to meet various requirements of consumers, the preparation process is scientific and reasonable, segmented stirring and temperature control are performed, specific components are added and treated, the product quality is ensured, finally, a high-temperature instantaneous sterilization method is adopted, the product safety and stability are ensured, the microbial index standard is met, and in a word, the preparation method is suitable for industrial production. The invention has obvious advantages and wide market prospect.