102 results about "Royal jelly" patented technology

The invention relates to the technical field of small molecule peptide royal jelly production control, in particular to a small molecule peptide royal jelly production control method and system. Comprising the following steps: applying preset tiny pH disturbance to an enzymolysis reaction solution to obtain a pH change curve, and extracting transient response performance data; acquiring at least one auxiliary response data, and performing cross validation on the transient response performance data and the auxiliary response data to obtain a corrected pH value; monitoring the generation rate of the protein hydrolysate, and obtaining a reversely deduced pH value according to a pre-established enzyme pH-activity relation model; calculating a pH measurement reliability index based on the transient response performance data, the corrected pH value and the inversely deduced pH value; and self-adaptive adjustment is carried out according to the pH measurement reliability index. The problems of measurement deviation caused by aging of the pH probe in the production of the small molecule peptide royal jelly, reduction of the enzymolysis efficiency, damage to the product quality, increase of the production cost and the like caused by the measurement deviation are solved.

The utility model relates to the technical field of royal jelly processing equipment, in particular to a royal jelly concentration device, which comprises a concentration box, a front doorway is arranged on the concentration box, a box door is arranged at the doorway, a containing groove is arranged in the concentration box, an air blowing pipe is led to the concentration box, and an exhaust pipe is led out from the concentration box. A supporting frame is further installed on the upper portion of the interior of the concentration box, a dripping groove is further installed on the supporting frame, a plurality of evenly-distributed dripping small holes are formed in the lower portion of the dripping groove, and the dripping small holes are formed in the upper portion of the containing groove; a suction pipe is connected with the containing groove and the dripping groove, a suction pump is installed in the middle of the suction pipe, and the royal jelly in the containing groove can be conveyed into the dripping groove. The royal jelly concentration device has the advantages of high concentration efficiency and good product homogeneity.

The utility model provides a raw material cold storage device for royal jelly lozenge production, and relates to the royal jelly lozenge production field, the raw material cold storage device comprises a main body unit, the main body unit comprises a freezer body, the front side of the freezer body is hinged with a cabinet door through a hinge, and the inner cavity of the cabinet door is fixedly connected with toughened glass; an inner cavity of the freezer body is fixedly connected with a partition plate; the freezer body and the freezer door provide a refrigeration environment for royal jelly raw materials, freshness and quality of the royal jelly raw materials are kept, the tempered glass can enhance the strength and transparency of the freezer door, the situation inside the freezer body can be observed conveniently, and the containing groove, the polyvinyl chloride sealing frame and the polyvinyl chloride sealing plate are matched so that operation is convenient. The sealing connection between the food-grade plastic containing box and the partition plate is achieved, cold air leakage can be prevented, the situation that raw materials in other food-grade plastic containing boxes are polluted by external air when a door is opened to take a certain food-grade plastic containing box can also be prevented, and therefore the possibility that the royal jelly raw materials go bad is reduced, and losses are reduced.

This invention discloses a royal jelly purification device, relating to the field of royal jelly purification technology. It includes a purification cylinder containing a first filter assembly and a second filter assembly, with the first filter assembly positioned above the second filter assembly. The first filter assembly includes a first circular filter screen, horizontally arranged and fixedly installed within the purification cylinder. The second filter assembly includes a second circular filter screen, also horizontally arranged and fixedly installed within the purification cylinder. This invention features a novel design and simple operation. Through the arrangement of the first and second filter assemblies, the first filter assembly performs preliminary filtration and purification of the royal jelly, blocking larger impurities. The second filter assembly further filtration and purification of the royal jelly, blocking smaller impurities, resulting in excellent filtration and purification effects.

The utility model discloses a royal jelly collecting device which comprises a collecting assembly, the collecting assembly comprises a connecting pipe, a first piston is installed on the surface of an inner cavity of the upper side of the connecting pipe in a sliding mode, a pressing column is fixedly installed on the outer surface of the upper end of the first piston, a spring is arranged on the outer side of the pressing column, and a connecting column is fixedly installed on the outer surface of the lower end of the first piston. A second piston is fixedly installed on the outer surface of one end of the connecting column, a collecting pipe is fixedly installed on the outer surface of one end of the connecting pipe, the pressing column is pushed to drive the first piston and the second piston to slide on the inner wall of the connecting pipe through the arranged collecting assembly, meanwhile, the spring is stretched, then the collecting pipe is placed in a honeycomb of a queen bee cell, and at the moment, the pressing column is loosened; due to the fact that the first piston and the second piston are driven by the elastic force of the spring to slide and reset, royal jelly in the honeycomb is sucked into the inner cavity of the upper side of the connecting pipe, and by means of the structure, royal jelly collection is achieved, damage to a queen bee cell is reduced, and the royal jelly collection efficiency and quality are improved.

The application discloses a kind of β-hairpin structure self-assembly capture antibacterial peptide J-1-RF and its application, it is related to biological medicine technical field.The amino acid sequence of the β-hairpin structure self-assembly capture antibacterial peptide J-1-RF is as shown in SEQ ID NO.4.The application selects the broad-spectrum antibacterial short peptide J-1 derived from honeybee royal jelly as template peptide, designs and transforms according to the amino acid sequence characteristics of short peptide J-1, obtains hydrophilic and hydrophobic amino acid alternately arranged structure unit, and uses it as self-assembly peptide fiber skeleton. D PG and RRRF two turning sequences are used for β-hairpin peptide design, so that it has the dual effect of antibacterial and bacterial capture.The β-hairpin structure self-assembly capture antibacterial peptide J-1-RF provided by the application can form fiber network structure, has good bacteriostatic effect and high stability, and has excellent biocompatibility, which provides effective technical support for developing new antibacterial drugs.

The present application relates to a kind of whitening anti-aging composition suitable for sensitive skin and its application, belong to the technical field of cosmetics.The composition includes Psoralea corylifolia phenol, hydrolyzed royal jelly protein, radix notoginseng extract and camellia sinensis var. assamica flower extract as active ingredient.Psoralea corylifolia phenol has the effects of anti-aging, antioxidant and anti-inflammatory, etc.;Hydrolyzed royal jelly protein can help to relieve skin discomfort, moisturizing, enhance skin barrier function, etc.;Camellia sinensis var. assamica flower extract has the effects of anti-photoaging, whitening and anti-inflammatory soothing, while radix notoginseng extract has the effects of anti-inflammatory, antioxidant and anti-aging, etc.The composition of the present application can synergistically enhance the effects of anti-inflammatory, whitening and anti-aging by reasonable allocation of the above components, and the composition contains natural components, is mild and non-irritating, suitable for sensitive skin, and can be applied to various cosmetics.

The application provides a Pickering emulsion with slow-release antibacterial function and a preparation method and application thereof, and relates to the technical field of Pickering emulsions. Raw materials of the Pickering emulsion include royal jelly extract liquid and yizhi essential oil in a volume ratio of 1.5-2.5:1, and the volume fraction of the yizhi essential oil in the Pickering emulsion is 60%-70%, the royal jelly extract liquid is obtained by dispersing royal jelly protein extract in water, and the obtained dispersion liquid has a protein concentration of 40-50 mg / mL. The Pickering emulsion takes the royal jelly protein extract as a natural particle stabilizer, and loads the yizhi essential oil, and through accurate control of the volume fraction of the yizhi essential oil and the protein concentration in the royal jelly extract liquid, excellent antibacterial, antioxidant activity and volatile component slow-release characteristics are exhibited. The Pickering emulsion can not only be used as a nutritionally fortified 3D printing food base material for patients with difficulty in swallowing, but also be used as an active additive for pharmaceutical preparations and cosmetics, and has wide application value.

The invention discloses a preparation method and application of enzymolysis royal jelly capable of whitening skin, fading spots and resisting wrinkles, and belongs to the technical field of enzymolysis of royal jelly. The technical problem to be solved is that the existing royal jelly zymolyte is lack of research having the effects of whitening, fading spots and resisting wrinkles. The key point of the technical scheme is that the preparation method of the enzymolysis royal jelly comprises the following steps: (1) mixing and homogenizing royal jelly and water, and adjusting the pH value to obtain a royal jelly solution; (2) adding compound protease into the royal jelly solution for enzymolysis, and performing enzyme deactivation and solid-liquid separation to obtain royal jelly enzymatic hydrolysate; the compound protease in the step (2) is fig protease, chymotrypsin and flavourzyme.

Disclosed in the present invention is a use of royal jelly extracellular vesicles (RJEVs) in the preparation of a pharmaceutical composition for treating wounds in individuals suffering from diabetes, wherein the pharmaceutical composition comprises at least one carrier, and the at least one carrier has the characteristics of adhering to the skin of the individuals.

A herbal composition for supporting restoration of digestive system function comprising the following components: a Leucaena leucocephala extract, an eleutherin extract component from Eleutherine bulbosa, an Andrographis paniculata extract, a Panax vietnamensis extract, a Pouzolzia zeylanica extract, a first herbal mixture extract, a second herbal mixture extract, a sugar, a salt, a honey, a royal jelly, a vegetable oil, and a plant powder. Method for producing the composition comprising: (i) preparing materials; (ii) creating a base mixture; (iii) creating a first temporary mixture; (iv) creating a second temporary mixture; (v) creating a third temporary mixture; (vi) creating a fermented mixture; and (vii) packaging the fermented mixture to obtain the herbal composition for supporting restoration of digestive system function.

This invention discloses a skin cream for chapped hands and feet and its preparation process, belonging to the field of skin cream preparation technology. The skin cream is composed of ginseng leaf and stem extract, royal jelly, glycerin, octadecanol, glyceryl stearate, liquid paraffin, sodium lauryl sulfate, ethylparaben, fragrance, and purified water in a specific mass ratio. Its preparation process includes steps such as heating and melting the oil and water phases separately, emulsifying and stirring, cooling and adding active ingredients, and aging. This product, through the synergistic effect of moisturizing and active repairing ingredients, can effectively relieve dry and cracked skin, promote healing, and has the advantages of stable formula, gentle skin feel, and high safety.

The application relates to a preparation method and application of royal jelly acid double-wrapped bodies, and belongs to the technical field of cosmetics. The royal jelly acid double-wrapped body prepared by the application is obtained by co-wrapping royal jelly acid by phospholipid lipids and hydroxypropyl-beta-cyclodextrin, and the double-wrapping system of the hydroxypropyl-beta-cyclodextrin and the liposome improves the loading capacity of the royal jelly acid, has good stability, can significantly improve the solubility of the royal jelly acid, and is convenient for application in cosmetics; compared with pure royal jelly acid, the royal jelly acid double-wrapped body prepared by the application has more excellent skin permeability and more excellent effect of improving the content of type IV collagen of skin, and can provide mechanical support for skin and maintain the young state of skin.

1. Name of the product in this design: Packaging Box (Kanglaoda Brand Astragalus Ginseng Royal Jelly Oral Liquid). 2. Purpose of this design: For packaging the corresponding product of Kanglaoda brand Astragalus Ginseng Royal Jelly Oral Liquid. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

Pharmaceutical or cosmetic composition comprising the following components: a) a dermatologically suitable carrier material, b) a first active substance, and c) a second active substance; wherein d) the first active substance comprises royal jelly; and e) the second active substance comprises retinol, a retinol analogue or a mixture thereof.

The application discloses a kind of pure natural royal jelly freeze-dried powder detection methods, it is related to quality detection technical field, the method includes the following steps: collecting the multi-dimensional original data of royal jelly freeze-dried powder, data is handled to generate data matrix, from data matrix extraction key feature index set, to index set is analyzed and evaluated to generate authenticity score, generate digital detection report and quality spectrum, based on detection result is continuously optimized.The application, by fusing near-infrared spectrum, microscopic image, physicochemical activity and block chain traceability and other multi-source heterogeneous data, intelligent evaluation is carried out using knowledge graph and lightweight multi-modal network, realizes the multi-dimensional, high-precision analysis of the pure nature, naturalness and adulteration of royal jelly freeze-dried powder.

The utility model provides a royal jelly ultra-high pressure treatment device, which relates to the field of ultra-high pressure treatment devices and comprises a device base, a hydraulic cylinder is arranged on the upper side of the device base, two ends of the hydraulic cylinder are connected with a first high pressure container and a second high pressure container, and guide ports are arranged on the upper sides of the first high pressure container and the second high pressure container. The two ends of the hydraulic cylinder are movably connected with a first push rod and a second push rod, the outer end of the first push rod is connected with a first piston, the outer end of the second push rod is connected with a second piston, and the first piston and the second piston are slidably connected into the first high-pressure container and the second high-pressure container respectively. The taking and placing assembly comprises a fixing frame, an electric push rod is connected to the inner side of the fixing frame, a sealing plug is connected to the lower end of the electric push rod, and meanwhile a hanging basket is connected to the lower end of the sealing plug through a connecting rod. According to the utility model, food to be processed is convenient to take and place, and the high-pressure processing efficiency is improved.

The invention discloses a royal jelly oil control composition. The preparation method of the royal jelly oil-control composition comprises the following steps: freeze-drying collected fresh royal jelly, then putting the material into a supercritical extraction kettle, and introducing CO2 containing an ethanol additive for extraction to obtain a royal jelly fat-soluble component; adding the royal jelly fat-soluble component, capryloyl glycine and ethanol into a reaction kettle, vacuumizing, then adding a carbon dioxide / nitrogen mixture, pressurizing and stirring; removing the pressure, and carrying out rotary evaporation to remove ethanol to obtain a crude product; adding a solvent into the crude product, and stirring and dissolving under ultrasound; centrifuging, and taking supernate, so as to obtain the royal jelly oil control composition. According to the royal jelly oil control composition, a water-soluble supramolecular layered micelle structure is formed through the intermolecular non-covalent bond effect, so that the problem that the composition is insoluble in water is solved, continuous release of active ingredients is realized through a non-covalent bond network, and the bioavailability is improved.

The invention relates to beekeeping, in particular to a process for producing royal jelly.The process, according to the invention, includes the introduction into the breeding family of frames equipped with qeen cells with transferred larvae and the daily feeding of the nurse bees, in the absence of a maintenance honey flow, with a mixture of sugar syrup and a biostimulator, for 3 days, after which the frames are removed from the hive to collect the royal jelly, and the procedure is repeated twice, at the same time the biostimulator is an aqueous solution containing: D-glucuronic acid, potassium hydroxide, choline chloride and water.

The application discloses a preparation method and application of royal jelly acid, and belongs to the technical field of chemical synthesis, and solves the problem that the preparation of royal jelly acid in the prior art cannot have simple steps and mild conditions. The method comprises the following steps: 9-bromo-1 nonene and acrylic acid are subjected to esterification reaction under the action of an organic solvent and an alkali, so that acrylic acid-8-nonene-1-yl ester is obtained, and the structural formula is shown as formula I; under the action of a catalyst, the acrylic acid-8-nonene-1-yl ester is subjected to olefin metathesis reaction, so that a compound with a structural formula shown as formula II is obtained; after hydrolysis reaction under alkaline conditions, acidification is performed, so that royal jelly acid is obtained. The method provided by the application has the advantages of wide raw material sources, relatively low price, improved synthesis efficiency and product yield, reduced equipment cost and production risk, and is beneficial to the implementation of industrialized production.

1.The name of the design product: packaging box (ginseng royal jelly). 2.The use of the design product: mainly used for product packaging. 3.The design points of the design product: the combination of shape, pattern and color. 4.The picture or photo that best shows the design points: perspective view. 5.The design claimed contains color.

The application discloses a royal jelly quality evaluation method based on bacteriostatic activity, and belongs to the technical field of bioengineering and food quality evaluation. The method evaluates the quality of royal jelly by determining the bacteriostatic activity of the royal jelly. Specifically, the royal jelly to be measured is diluted to 10% volume concentration, then the bacteriostatic activity of the diluted royal jelly on indicator bacteria is determined by adopting a filter paper method, and the quality grade of the royal jelly to be measured is determined according to the bacteriostatic ring diameter. The quality of the royal jelly is evaluated by determining the bacteriostatic activity of the royal jelly, the influence of water content, 10-HDA and freshness on the quality of the royal jelly is considered in principle, the method has the characteristics of simple operation and intuitive evaluation, and is easy to popularize and apply, thereby laying an important foundation for the quality detection technology of royal jelly.

The invention relates to the technical field of biological-high polymer material composite fiber membranes, and particularly discloses a method and device for rapidly preparing royal jelly nanofibers through an electronic spinning technology. Chitosan is taken and added into an acetic acid aqueous solution to obtain a chitosan solution; adding polyvinyl alcohol into deionized water to obtain a polyvinyl alcohol solution; blending the chitosan solution and the polyvinyl alcohol solution to obtain a spinning solution I; taking deionized water, and adjusting the pH value of the deionized water to a limited acidity through acetic acid to obtain acidity water; dissolving royal jelly in acidity water to obtain a royal jelly solution; mixing the royal jelly solution with the spinning solution I to obtain a spinning solution II; performing ultrasonic treatment on the spinning solution II to obtain a spinning solution III; filling the spinning solution III into an injector; wrapping a spinning receiving film on a rotary collector of the spinning machine; the received royal jelly nanofiber is subjected to gradient dehumidification and drying, and a royal jelly nanofiber finished product is obtained. The preparation method has the characteristics that active ingredients are not damaged, the release rate of bioactive substances is not influenced, and the product quality is good.

The invention relates to the technical field of royal jelly filling, and provides a royal jelly low-temperature filling device and technology.The royal jelly low-temperature filling device comprises a royal jelly storage barrel, a cooling water machine and a royal jelly suction head, a filling structure is arranged at the bottom of the royal jelly storage barrel, the royal jelly low-temperature filling device further comprises a cooling interlayer and a royal jelly conveying pipeline, and the cooling interlayer is arranged on the inner side wall of the royal jelly storage barrel; a water outlet of the cooling-water machine is communicated with the cooling interlayer, a separation sleeve is fixedly connected in the slurry storage barrel and internally divided into a pipeline moving-out cavity and a circulating water discharging cavity, a water inlet of the cooling-water machine is communicated with the circulating water discharging cavity, the slurry conveying pipeline is arranged in the pipeline moving-out cavity, and the slurry suction head is communicated with one end of the slurry conveying pipeline. The other end of the slurry conveying pipeline penetrates through the pipeline to move out of the cavity, and the outer side of the slurry conveying pipeline is sleeved with a low-temperature sleeve. According to the technical scheme, the problem that it is difficult to ensure that royal jelly is always in a low-temperature environment in the royal jelly taking, storing and filling processes in the prior art is solved.

The utility model relates to the technical field of filtering devices, and discloses a filtering device for royal jelly processing, which comprises a shell, a sliding rail is fixedly connected to the middle of the shell, a sliding strip is slidably connected to the interior of the sliding rail, a rack is fixedly connected to the side surface of the sliding strip, and a mounting box is fixedly connected to the front side of the sliding rail. A gear is rotatably connected to the middle of the mounting box, a support is fixedly connected to the side face of the shell, a motor is fixedly connected to the side face of the support, a mounting frame is rotatably mounted on the surface of the rotating disc, rollers are rotatably connected to the middle of the mounting frame, and a moving frame is fixedly connected to the end of a sliding strip. Through rotation of the motor, rotation of the turntable and movement of the mounting rack, the moving frame is forced to move back and forth, the sliding strip moves back and forth, the rack moves along with the sliding strip, the gear rotates in the mounting box, the filter screen rotates along with the gear, royal jelly falls on the filter screen, the royal jelly can be thrown out, and the filtering efficiency is improved.

The invention relates to the technical field of traditional Chinese medicine compositions, and discloses a traditional Chinese medicine compound composition for adjuvant therapy of cancers and a preparation method thereof. Comprising the following traditional Chinese medicine components in parts by weight: 5-10 parts of scorpio, 10-20 parts of royal jelly freeze-dried powder, 5-15 parts of ginseng, 10-20 parts of rhizoma polygonati, 10-30 parts of astragalus membranaceus, 5-15 parts of dendrobium officinale, 10-20 parts of rehmannia, 5-15 parts of lucid ganoderma, 10-30 parts of oldenlandia diffusa, 10-20 parts of radix ophiopogonis, 5-15 parts of dogwood, 10-20 parts of codonopsis pilosula, 5-15 parts of liquorice, 0.1-0.5 part of selenium yeast, 5-15 parts of edible tulip, 10-20 parts of hawthorn, 5-15 parts of chrysanthemum and 10-30 parts of dandelion. And 3-10 parts of cinnamon. The scorpion, the pseudobulbus cremastrae seu pleiones and other components can directly inhibit tumor cell proliferation and induce apoptosis; the selenium yeast can scavenge free radicals and inhibit tumor angiogenesis. The royal jelly freeze-dried powder, the ginseng, the astragalus membranaceus, the lucid ganoderma and the like can activate immune cells, improve the immune monitoring ability of a body and relieve immunosuppression caused by radiotherapy and chemotherapy.

The utility model discloses a royal jelly freeze-drying device. A box body; the bottom plate is arranged in the box body in a sliding manner; the winding rollers are symmetrically arranged at the bottom end of the box body and are in running fit; the thin film is fixedly mounted on the winding roller and movably connected to the bottom plate; the rubber block is arranged in the box body in a sliding mode and abuts against the thin film. According to the royal jelly freeze-drying device provided by the utility model, the box body and the bottom are matched to form a tray, so that royal jelly can be directly poured into the box body to be freeze-dried, the end face of the bottom plate is covered by the matching of the winding roller and the thin film, and the freeze-dried royal jelly is adhered to the thin film; according to the royal jelly freeze-drying device, the film is wound in one direction by driving one winding roller, so that royal jelly is separated from the film, the royal jelly can be pushed out of the box body by driving the bottom plate to move upwards, the problem that freeze-dried royal jelly is attached to a tray and is difficult to take out is solved, the production efficiency of the royal jelly is improved, and the workload of workers is reduced.

The application provides a preparation method of small molecule enzyme hydrolysis royal jelly with improved absorption, and belongs to the technical field of royal jelly preparation. The method comprises the following steps: (1) preparing a royal jelly aqueous solution; (2) taking the royal jelly aqueous solution, adjusting the pH value to 7-8, then adding sea cucumber hydrolytic enzyme and aminopeptidase, performing enzyme hydrolysis, sterilizing, and obtaining enzyme hydrolysate 1; (3) taking the enzyme hydrolysate 1, adjusting the pH value to 1-2, adding pepsin, performing enzyme hydrolysis, sterilizing, and freeze-drying to obtain the small molecule enzyme hydrolysis royal jelly. The small molecule enzyme hydrolysis royal jelly prepared by the method has a peptide segment molecular weight less than or equal to 1000 Da, wherein the proportion of the peptide segment molecular weight less than or equal to 500 Da is greater than or equal to 80%, the small molecule enzyme hydrolysis royal jelly is easy to be absorbed and utilized by the human body, and has high bioavailability.

The utility model provides a filtering device for royal jelly processing, which solves the problems that the continuously added royal jelly applies pressure to a filter screen to cause local elastic deformation of the filter screen, so that a gap between a concave area of the filter screen and a scraper blade is increased, the scraping and sweeping effect of partial area is invalid, filter residues cannot be effectively scraped off to block the filter screen, and the service life of the filter screen is prolonged. The filtering efficiency of the royal jelly is influenced. The corrugated pipe coupling is arranged between the output shaft of the driving motor used for driving the arc-shaped scraping plate and the driving shaft, and the corrugated pipe coupling is pre-compressed during initial installation, so that the arc-shaped scraping plate is pressed to abut against the first filter screen, and when the first filter screen is concave downwards, the corrugated pipe coupling axially stretches out and draws back to compensate displacement; the arc-shaped scraping plate is always attached to the surface of the first filter screen, the situation that a gap between the concave area of the first filter screen and the arc-shaped scraping plate is increased, consequently, the scraping and sweeping effect of part of the area is invalid is avoided, and therefore the situation that filter residues cannot be effectively scraped, the first filter screen is blocked, and the royal jelly filtering efficiency is affected is avoided.