163 results about "Royal jelly" patented technology

The invention relates to a whitening and anti-aging composition suitable for sensitive skin and application of the whitening and anti-aging composition, and belongs to the technical field of cosmetics. The composition comprises bakuchiol, hydrolyzed royal jelly protein, a radix pseudostellariae extract and a golden camellia flower extract as active ingredients. The bakuchiol has the effects of resisting aging, resisting oxidation, resisting inflammation and the like; the hydrolyzed royal jelly protein can help to relieve skin discomfort, preserve moisture, enhance the skin barrier function and the like; the golden camellia flower extract has the effects of resisting light aging, whitening skin, fading spots, resisting inflammation and relieving allergy, and the radix pseudostellariae extract has the effects of resisting inflammation, resisting oxidation, resisting aging and the like. According to the composition disclosed by the invention, through reasonable blending of the components, synergistic interaction can be realized, the effects of resisting inflammation, whitening and delaying senescence are remarkably improved, and the composition contains natural components, is mild and non-irritant, is suitable for sensitive skin and can be applied to various cosmetics.

The invention belongs to the technical field of cosmetics, and particularly relates to a camellia-seed oil composition with anti-oxidation and whitening effects and application of the camellia-seed oil composition. The camellia seed oil composition comprises the following components in parts by weight: 1-8 parts of camellia seed oil, 0.5-5 parts of hydrolyzed royal jelly protein and 1-5 parts of fermented cynara plantaginis seed oil. According to the composition, the camellia seed oil, the hydrolyzed royal jelly protein and the fermented plantain herb seed oil are organically combined, and the composition with the anti-oxidation and whitening effects is researched and developed. Experiments and exploration find that the three components are matched with one another in a preferable dosage range of the whitening composition, an ideal synergistic effect can be achieved, free radicals can be effectively resisted, skin aging can be delayed, uneven skin color can be remarkably improved, color spots can be remarkably lightened, and a good whitening effect can be achieved.

The utility model discloses an unfreezing device for royal jelly processing, which belongs to the technical field of royal jelly unfreezing and comprises a water bath box for storing hot water for unfreezing royal jelly and a storage tank for storing royal jelly, an inverted U-shaped support plate is welded on the top surface of the water bath box, and a linear motor is mounted on the inner top wall of the support plate. A moving part of the linear motor is fixedly connected with a connecting plate, an inverted-U-shaped connecting frame is welded to the bottom face of the connecting plate, limiting bearings are fixedly connected to the two side walls of the connecting frame in an embedded mode, inner rings of the limiting bearings are in interference fit with connecting rods with square channels, square inserting rods are slidably connected to the inner walls of the connecting rods, and rotating blocks are welded to the end faces of the inserting rods. According to the royal jelly unfreezing device disclosed by the utility model, the royal jelly is fully heated and unfrozen, so that the unfreezing effect of the unfreezing device on the royal jelly is improved.

The invention discloses bioactive gel for accelerating wound healing. The gel is prepared from the following raw materials in percentage by weight: 0.8%-1% of bomer 980, 5%-5.5% of glycerol, 15%-20% of white vaseline, 51.7%-55% of phosphate buffer, 1.8%-2% of nano royal jelly acid, 2%-3% of recombinant III type human collagen, 0.4%-0.5% of sodium hyaluronate, 1%-3% of sodium alginate, 20%-25% of polyethylene glycol-400, 1.5%-3% of dopamine-methacrylamide copolymer, 0.5%-0.8% of nano silver and 0.3%-0.5% of phenoxyethanol. The nano royal jelly acid and the nano silver have a synergistic antibacterial effect, so that the inhibition effect on drug-resistant bacteria such as MRSA and pseudomonas aeruginosa is remarkably improved, and meanwhile, the wound epithelization can be accelerated and scar formation can be reduced through the dual effects of the recombinant III type collagen and the acetylated sodium hyaluronate. The defects that a traditional dressing is narrow in antibacterial spectrum, single in repairing effect, poor in environmental adaptability and the like are overcome, and the dressing is particularly suitable for complicated wounds such as diabetic foot ulcer and second-degree burn.

The invention discloses low-temperature processing equipment for preparing freeze-dried powder from royal jelly, and relates to the field of low-temperature processing.The low-temperature processing equipment comprises a bin body, bin doors are arranged at the front end and the rear end of the bin body, a support is vertically arranged in the bin body, four telescopic rods are arranged in the support, and every two telescopic rods on the same side form a group; inserting blocks are arranged at the opposite ends of the two telescopic rods in each set, springs are arranged on the outer surfaces of the telescopic rods, and trays are placed at the top ends of the multiple supports. By arranging a series of structures, the equipment automation is improved, the efficiency is improved, during royal jelly feeding, manual intervention is reduced, dust is prevented from falling into pulp during manual feeding, the cleanliness of royal jelly is ensured, the situation that bubbles affect the quality and yield of freeze-dried powder after freeze-drying is avoided, and the production efficiency is improved. The royal jelly liquid is prevented from generating heat to influence the activity after being blended and filtered, and meanwhile, the royal jelly liquid is pre-cooled in advance, so that subsequent quick freezing is facilitated, and an ice crystal structure is formed.

The invention belongs to the technical field of biological medicines, and particularly relates to a royal jelly acid derivative and a synthesis method, a pharmaceutical composition and application thereof. The royal jelly acid derivative is a compound shown as a formula (I), or an enantiomer, a diastereoisomer and a tautomer thereof, or a solvate or a pharmaceutically acceptable salt thereof. A series of royal jelly acid derivatives with novel structures are constructed by using a natural component royal jelly acid derived from royal jelly as an initial raw material, the royal jelly acid derivatives can play a role in resisting pulmonary fibrosis by inhibiting the activity of fibroblasts, the effect of the royal jelly acid derivatives is equivalent to that of pirfenidone, and the royal jelly acid derivatives are expected to be developed into candidate drugs for resisting pulmonary fibrosis. The ceramide NP has excellent effects in anti-inflammatory, anti-allergic and itching-relieving aspects, has a better effect than known ceramide NP, and can be used for preparing health care products, cosmetics and medicines. And # imgabs0 #.

The invention relates to the technical field of small molecule peptide royal jelly production control, in particular to a small molecule peptide royal jelly production control method and system. Comprising the following steps: applying preset tiny pH disturbance to an enzymolysis reaction solution to obtain a pH change curve, and extracting transient response performance data; acquiring at least one auxiliary response data, and performing cross validation on the transient response performance data and the auxiliary response data to obtain a corrected pH value; monitoring the generation rate of the protein hydrolysate, and obtaining a reversely deduced pH value according to a pre-established enzyme pH-activity relation model; calculating a pH measurement reliability index based on the transient response performance data, the corrected pH value and the inversely deduced pH value; and self-adaptive adjustment is carried out according to the pH measurement reliability index. The problems of measurement deviation caused by aging of the pH probe in the production of the small molecule peptide royal jelly, reduction of the enzymolysis efficiency, damage to the product quality, increase of the production cost and the like caused by the measurement deviation are solved.

The utility model relates to the technical field of royal jelly processing equipment, in particular to a royal jelly concentration device, which comprises a concentration box, a front doorway is arranged on the concentration box, a box door is arranged at the doorway, a containing groove is arranged in the concentration box, an air blowing pipe is led to the concentration box, and an exhaust pipe is led out from the concentration box. A supporting frame is further installed on the upper portion of the interior of the concentration box, a dripping groove is further installed on the supporting frame, a plurality of evenly-distributed dripping small holes are formed in the lower portion of the dripping groove, and the dripping small holes are formed in the upper portion of the containing groove; a suction pipe is connected with the containing groove and the dripping groove, a suction pump is installed in the middle of the suction pipe, and the royal jelly in the containing groove can be conveyed into the dripping groove. The royal jelly concentration device has the advantages of high concentration efficiency and good product homogeneity.

The utility model provides a raw material cold storage device for royal jelly lozenge production, and relates to the royal jelly lozenge production field, the raw material cold storage device comprises a main body unit, the main body unit comprises a freezer body, the front side of the freezer body is hinged with a cabinet door through a hinge, and the inner cavity of the cabinet door is fixedly connected with toughened glass; an inner cavity of the freezer body is fixedly connected with a partition plate; the freezer body and the freezer door provide a refrigeration environment for royal jelly raw materials, freshness and quality of the royal jelly raw materials are kept, the tempered glass can enhance the strength and transparency of the freezer door, the situation inside the freezer body can be observed conveniently, and the containing groove, the polyvinyl chloride sealing frame and the polyvinyl chloride sealing plate are matched so that operation is convenient. The sealing connection between the food-grade plastic containing box and the partition plate is achieved, cold air leakage can be prevented, the situation that raw materials in other food-grade plastic containing boxes are polluted by external air when a door is opened to take a certain food-grade plastic containing box can also be prevented, and therefore the possibility that the royal jelly raw materials go bad is reduced, and losses are reduced.

This invention discloses a royal jelly purification device, relating to the field of royal jelly purification technology. It includes a purification cylinder containing a first filter assembly and a second filter assembly, with the first filter assembly positioned above the second filter assembly. The first filter assembly includes a first circular filter screen, horizontally arranged and fixedly installed within the purification cylinder. The second filter assembly includes a second circular filter screen, also horizontally arranged and fixedly installed within the purification cylinder. This invention features a novel design and simple operation. Through the arrangement of the first and second filter assemblies, the first filter assembly performs preliminary filtration and purification of the royal jelly, blocking larger impurities. The second filter assembly further filtration and purification of the royal jelly, blocking smaller impurities, resulting in excellent filtration and purification effects.

The utility model discloses a royal jelly collecting device which comprises a collecting assembly, the collecting assembly comprises a connecting pipe, a first piston is installed on the surface of an inner cavity of the upper side of the connecting pipe in a sliding mode, a pressing column is fixedly installed on the outer surface of the upper end of the first piston, a spring is arranged on the outer side of the pressing column, and a connecting column is fixedly installed on the outer surface of the lower end of the first piston. A second piston is fixedly installed on the outer surface of one end of the connecting column, a collecting pipe is fixedly installed on the outer surface of one end of the connecting pipe, the pressing column is pushed to drive the first piston and the second piston to slide on the inner wall of the connecting pipe through the arranged collecting assembly, meanwhile, the spring is stretched, then the collecting pipe is placed in a honeycomb of a queen bee cell, and at the moment, the pressing column is loosened; due to the fact that the first piston and the second piston are driven by the elastic force of the spring to slide and reset, royal jelly in the honeycomb is sucked into the inner cavity of the upper side of the connecting pipe, and by means of the structure, royal jelly collection is achieved, damage to a queen bee cell is reduced, and the royal jelly collection efficiency and quality are improved.

The special royal jelly filtering device comprises a box body and a flow guide plate, the bottom of an inner cavity of the box body is movably connected with a transmission shaft through a sealing bearing, the lower surface of the box body is fixedly connected with a main motor, the main motor is connected with the lower end of the transmission shaft through a coupler, and the upper end of the transmission shaft is fixedly connected with the lower surface of a filtering cylinder through a connecting piece. The base is fixedly connected to the bottom of an inner cavity of the box through a supporting rod, the guide plate is slidably connected to the inner side face of the box through a main sliding block, the outer side face of the guide plate is fixedly connected with a heating assembly, the upper surface of the guide plate is fixedly connected with a limiting plate, and the inner side face of the limiting plate is slidably connected with the outer side face of a filter cartridge. According to the royal jelly filtering device, through cooperation of the main motor, the transmission shaft, the positioning ring, the partition plate and the limiting plate, the filtering cylinder can stably rotate in the box body, then royal jelly in the filtering cylinder can be rapidly filtered under the action of centrifugal force, and the royal jelly filtering efficiency of the device is improved.

The application discloses a kind of β-hairpin structure self-assembly capture antibacterial peptide J-1-RF and its application, it is related to biological medicine technical field.The amino acid sequence of the β-hairpin structure self-assembly capture antibacterial peptide J-1-RF is as shown in SEQ ID NO.4.The application selects the broad-spectrum antibacterial short peptide J-1 derived from honeybee royal jelly as template peptide, designs and transforms according to the amino acid sequence characteristics of short peptide J-1, obtains hydrophilic and hydrophobic amino acid alternately arranged structure unit, and uses it as self-assembly peptide fiber skeleton. D PG and RRRF two turning sequences are used for β-hairpin peptide design, so that it has the dual effect of antibacterial and bacterial capture.The β-hairpin structure self-assembly capture antibacterial peptide J-1-RF provided by the application can form fiber network structure, has good bacteriostatic effect and high stability, and has excellent biocompatibility, which provides effective technical support for developing new antibacterial drugs.

The present application relates to a kind of whitening anti-aging composition suitable for sensitive skin and its application, belong to the technical field of cosmetics.The composition includes Psoralea corylifolia phenol, hydrolyzed royal jelly protein, radix notoginseng extract and camellia sinensis var. assamica flower extract as active ingredient.Psoralea corylifolia phenol has the effects of anti-aging, antioxidant and anti-inflammatory, etc.;Hydrolyzed royal jelly protein can help to relieve skin discomfort, moisturizing, enhance skin barrier function, etc.;Camellia sinensis var. assamica flower extract has the effects of anti-photoaging, whitening and anti-inflammatory soothing, while radix notoginseng extract has the effects of anti-inflammatory, antioxidant and anti-aging, etc.The composition of the present application can synergistically enhance the effects of anti-inflammatory, whitening and anti-aging by reasonable allocation of the above components, and the composition contains natural components, is mild and non-irritating, suitable for sensitive skin, and can be applied to various cosmetics.

The application provides a Pickering emulsion with slow-release antibacterial function and a preparation method and application thereof, and relates to the technical field of Pickering emulsions. Raw materials of the Pickering emulsion include royal jelly extract liquid and yizhi essential oil in a volume ratio of 1.5-2.5:1, and the volume fraction of the yizhi essential oil in the Pickering emulsion is 60%-70%, the royal jelly extract liquid is obtained by dispersing royal jelly protein extract in water, and the obtained dispersion liquid has a protein concentration of 40-50 mg / mL. The Pickering emulsion takes the royal jelly protein extract as a natural particle stabilizer, and loads the yizhi essential oil, and through accurate control of the volume fraction of the yizhi essential oil and the protein concentration in the royal jelly extract liquid, excellent antibacterial, antioxidant activity and volatile component slow-release characteristics are exhibited. The Pickering emulsion can not only be used as a nutritionally fortified 3D printing food base material for patients with difficulty in swallowing, but also be used as an active additive for pharmaceutical preparations and cosmetics, and has wide application value.

The invention discloses a preparation method and application of enzymolysis royal jelly capable of whitening skin, fading spots and resisting wrinkles, and belongs to the technical field of enzymolysis of royal jelly. The technical problem to be solved is that the existing royal jelly zymolyte is lack of research having the effects of whitening, fading spots and resisting wrinkles. The key point of the technical scheme is that the preparation method of the enzymolysis royal jelly comprises the following steps: (1) mixing and homogenizing royal jelly and water, and adjusting the pH value to obtain a royal jelly solution; (2) adding compound protease into the royal jelly solution for enzymolysis, and performing enzyme deactivation and solid-liquid separation to obtain royal jelly enzymatic hydrolysate; the compound protease in the step (2) is fig protease, chymotrypsin and flavourzyme.

Disclosed in the present invention is a use of royal jelly extracellular vesicles (RJEVs) in the preparation of a pharmaceutical composition for treating wounds in individuals suffering from diabetes, wherein the pharmaceutical composition comprises at least one carrier, and the at least one carrier has the characteristics of adhering to the skin of the individuals.

A herbal composition for supporting restoration of digestive system function comprising the following components: a Leucaena leucocephala extract, an eleutherin extract component from Eleutherine bulbosa, an Andrographis paniculata extract, a Panax vietnamensis extract, a Pouzolzia zeylanica extract, a first herbal mixture extract, a second herbal mixture extract, a sugar, a salt, a honey, a royal jelly, a vegetable oil, and a plant powder. Method for producing the composition comprising: (i) preparing materials; (ii) creating a base mixture; (iii) creating a first temporary mixture; (iv) creating a second temporary mixture; (v) creating a third temporary mixture; (vi) creating a fermented mixture; and (vii) packaging the fermented mixture to obtain the herbal composition for supporting restoration of digestive system function.

This invention discloses a skin cream for chapped hands and feet and its preparation process, belonging to the field of skin cream preparation technology. The skin cream is composed of ginseng leaf and stem extract, royal jelly, glycerin, octadecanol, glyceryl stearate, liquid paraffin, sodium lauryl sulfate, ethylparaben, fragrance, and purified water in a specific mass ratio. Its preparation process includes steps such as heating and melting the oil and water phases separately, emulsifying and stirring, cooling and adding active ingredients, and aging. This product, through the synergistic effect of moisturizing and active repairing ingredients, can effectively relieve dry and cracked skin, promote healing, and has the advantages of stable formula, gentle skin feel, and high safety.

The application relates to a preparation method and application of royal jelly acid double-wrapped bodies, and belongs to the technical field of cosmetics. The royal jelly acid double-wrapped body prepared by the application is obtained by co-wrapping royal jelly acid by phospholipid lipids and hydroxypropyl-beta-cyclodextrin, and the double-wrapping system of the hydroxypropyl-beta-cyclodextrin and the liposome improves the loading capacity of the royal jelly acid, has good stability, can significantly improve the solubility of the royal jelly acid, and is convenient for application in cosmetics; compared with pure royal jelly acid, the royal jelly acid double-wrapped body prepared by the application has more excellent skin permeability and more excellent effect of improving the content of type IV collagen of skin, and can provide mechanical support for skin and maintain the young state of skin.

Process for the preparation of a stable and controlled release colloidal system of components of royal jelly, wherein said system is characterized by extracting the components of royal jelly and simultaneously encapsulating in a liposome-cyclodextrin combined carrier, to obtain a controlled release, taking advantage of the particular characteristics of both carriers, namely: the ability of cyclodextrins to encapsulate polyphenols and their enhanced skin penetration capacity, and the ability of liposomes to encapsulate a large number of components of various degrees of polarity, for local component transport and controlled release rate.

The present invention discloses a composition for improving sleep, preventing and treating anxiety, delaying aging and its preparation method. The composition includes lily, lemon balm, liquorice, mulberry, Poria, spinach seed, sea buckthorn, lotus seed core, roxburghii, alpinia oxyphylla, valerian root, acanthopanax senticosus, red rose, light bamboo leaf, snow lotus, gastrodia elata, passion flower, ergothioneine, dihydroquercetin, gamma-aminobutyric acid, casein peptide, royal jelly, pea peptide, tea theanine, fish collagen peptide and Haematococcus pluvialis powder. The composition of the present invention rationally proportions each component, and patient takes and is easy to carry, and is effective. In addition, the preparation method process of the composition is simple, stable and reliable in performance, high in production efficiency, low in production cost, and has broad application prospects.

1. Name of the product in this design: Packaging Box (Kanglaoda Brand Astragalus Ginseng Royal Jelly Oral Liquid). 2. Purpose of this design: For packaging the corresponding product of Kanglaoda brand Astragalus Ginseng Royal Jelly Oral Liquid. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

Pharmaceutical or cosmetic composition comprising the following components: a) a dermatologically suitable carrier material, b) a first active substance, and c) a second active substance; wherein d) the first active substance comprises royal jelly; and e) the second active substance comprises retinol, a retinol analogue or a mixture thereof.

The application discloses a kind of pure natural royal jelly freeze-dried powder detection methods, it is related to quality detection technical field, the method includes the following steps: collecting the multi-dimensional original data of royal jelly freeze-dried powder, data is handled to generate data matrix, from data matrix extraction key feature index set, to index set is analyzed and evaluated to generate authenticity score, generate digital detection report and quality spectrum, based on detection result is continuously optimized.The application, by fusing near-infrared spectrum, microscopic image, physicochemical activity and block chain traceability and other multi-source heterogeneous data, intelligent evaluation is carried out using knowledge graph and lightweight multi-modal network, realizes the multi-dimensional, high-precision analysis of the pure nature, naturalness and adulteration of royal jelly freeze-dried powder.

The invention belongs to the technical field of biology, and particularly relates to a sheep heart peptide composite nutritional product with balanced nutrition and a preparation process thereof, the sheep heart peptide composite nutritional product comprises the following components by mass percent: 10-30% of sheep heart peptide powder, 15-35% of whey protein powder, 5-15% of fructo-oligosaccharide, 3-10% of ginseng powder, 1-5% of vitamin C, 2-8% of royal jelly freeze-dried powder, and the balance of other auxiliary materials. The preparation method comprises the following steps: respectively sieving the raw materials, and then putting into a three-dimensional mixer; uniformly mixing, transferring to a subpackaging workshop, and subpackaging into small packages by using automatic quantitative subpackaging equipment; and shrinking, packaging, boxing and warehousing. According to the sheep heart peptide composite nutritional product prepared by the preparation method disclosed by the invention, various indexes meet related standard requirements through detection, and the sheep heart peptide composite nutritional product has good performance in the aspects of stability test, efficacy verification and the like and has a wide market application prospect.

The invention discloses a composite natural plant bee feed additive and application thereof, and relates to the technical field of bee feed additives. The rosemary powder and the thyme powder are combined to serve as the composite natural plant bee feed additive, and the prepared bee feed additive has multiple functions of nutrition supply, immunoregulation, antibiosis, antivirus, efficient mite killing and the like; the compound application of the rosemary and the thyme provides a new thought for solving the technical bottleneck of'nutrition-health-safety 'collaborative management of the bee colony. The rosmarinus officinalis and the thyme are combined to be used as the bee feed additive, and have a synergistic effect on inhibiting parasitism of the large bee mites and the small bee mites and improving the yield of the royal jelly.

The utility model provides a royal jelly ultra-high pressure treatment device, which relates to the field of ultra-high pressure treatment devices and comprises a device base, a hydraulic cylinder is arranged on the upper side of the device base, two ends of the hydraulic cylinder are connected with a first high pressure container and a second high pressure container, and guide ports are arranged on the upper sides of the first high pressure container and the second high pressure container. The two ends of the hydraulic cylinder are movably connected with a first push rod and a second push rod, the outer end of the first push rod is connected with a first piston, the outer end of the second push rod is connected with a second piston, and the first piston and the second piston are slidably connected into the first high-pressure container and the second high-pressure container respectively. The taking and placing assembly comprises a fixing frame, an electric push rod is connected to the inner side of the fixing frame, a sealing plug is connected to the lower end of the electric push rod, and meanwhile a hanging basket is connected to the lower end of the sealing plug through a connecting rod. According to the utility model, food to be processed is convenient to take and place, and the high-pressure processing efficiency is improved.

The invention discloses a royal jelly oil control composition. The preparation method of the royal jelly oil-control composition comprises the following steps: freeze-drying collected fresh royal jelly, then putting the material into a supercritical extraction kettle, and introducing CO2 containing an ethanol additive for extraction to obtain a royal jelly fat-soluble component; adding the royal jelly fat-soluble component, capryloyl glycine and ethanol into a reaction kettle, vacuumizing, then adding a carbon dioxide / nitrogen mixture, pressurizing and stirring; removing the pressure, and carrying out rotary evaporation to remove ethanol to obtain a crude product; adding a solvent into the crude product, and stirring and dissolving under ultrasound; centrifuging, and taking supernate, so as to obtain the royal jelly oil control composition. According to the royal jelly oil control composition, a water-soluble supramolecular layered micelle structure is formed through the intermolecular non-covalent bond effect, so that the problem that the composition is insoluble in water is solved, continuous release of active ingredients is realized through a non-covalent bond network, and the bioavailability is improved.

The invention relates to beekeeping, in particular to a process for producing royal jelly.The process, according to the invention, includes the introduction into the breeding family of frames equipped with qeen cells with transferred larvae and the daily feeding of the nurse bees, in the absence of a maintenance honey flow, with a mixture of sugar syrup and a biostimulator, for 3 days, after which the frames are removed from the hive to collect the royal jelly, and the procedure is repeated twice, at the same time the biostimulator is an aqueous solution containing: D-glucuronic acid, potassium hydroxide, choline chloride and water.