1360 results about "Lycopene" patented technology

A new method and system for desorption ionization is described and applied to the ionization of various compounds, including peptides and proteins present on metal, polymer, and mineral surfaces. Desorption electrospray ionization (DESI) is carried out by directing charged droplets and / or ions of a liquid onto the surface to be analyzed. The impact of the charged particles on the surface produces gaseous ions of material originally present on the surface. The resulting mass spectra are similar to normal ESI mass spectra in that they show mainly singly or multiply charged molecular ions of the analytes. The DESI phenomenon was observed both in the case of conductive and insulator surfaces and for compounds ranging from nonpolar small molecules such as lycopene, the alkaloid coniceine, and small drugs, through polar compounds such as peptides and proteins. Changes in the solution that is sprayed can be used to selectively ionize particular compounds, including those in biological matrices. In vivo analysis is demonstrated.

Disclosed are nutritional formulas, including reconstitutable powders, comprising carbohydrate, protein and a lipid component containing a polyunsaturated fatty acid; and from about 0.25 to about 10 ppm, by weight of the total oil content of the infant formula, of a combination of lutein, lycopene, and beta-carotene with preferred weight ratios of the lutein to beta-carotene of from about 0.0196:1 to about 59:1, the lycopene to beta-carotene of from about 0.00805:1 to about 114:1, and the lutein to lycopene of from about 0.0117:1 to about 108:1. Also disclosed are methods of providing nutrition using the disclosed formulas. The nutritional formulas provide improved product stability and color characteristics.

The invention relates to plant transcription factor polypeptides, polynucleotides that encode them, homologs from a variety of plant species, and methods of using the polynucleotides and polypeptides to produce transgenic plants having advantageous properties, including increased soluble solids, lycopene, and improved plant volume or yield, as compared to wild-type or control plants. The invention also pertains to expression systems that may be used to regulate these transcription factor polynucleotides, providing constitutive, transient, inducible and tissue-specific regulation.

The methods of the invention can be used to protect against lymphocyte DNA damage and free-radical associated disorders in a subject. The methods of the present invention can be used to increase the antioxidant capacity in both the aqueous and lipid compartments, decrease DNA oxidation, decrease lipid peroxidation, and increase antioxidant nutrient levels in the circulation. The protective effect of the physiologic dose of the mixed carotenoid supplement is rapid, consistent and cumulative.

A spectroscopic method, preferably Raman scattering, is used to rapidly determine the general health or stress status of living plants and plant products, including agricultural crops, forests, and harvested fruits and vegetables. In the preferred embodiments, carotenoid levels are used to provide an indication of oxidative deterioration. Based upon the results of the analysis, further action may or may not be taken, for example, in terms of choosing, picking, harvesting or sorting the agricultural product in accordance with the carotenoid level. Concentration levels of an analyte substance can be determined relative to an external standard, to each other, or relative to another substance in the item being analyzed. Carotenoids such as lycopene, beta-carotene, lutein, violaxanthin, neoxanthin, antheraxanthin, and zeaxanthin are determined according to the invention, through other plant components may be analyzed such as other terpenes, polyenes, chlorophyll, proteins, starches, sugars, overall nitrogen levels, flavonoids, and vitamins. The hardware associated with the invention may be field portable or mounted on a piece of equipment such as a harvester or sorter.

A new method and system for desorption ionization is described and applied to the ionization of various compounds, including peptides and proteins present on metal, polymer, and mineral surfaces. Desorption electrospray ionization (DESI) is carried out by directing charged droplets and / or ions of a liquid onto the surface to be analyzed. The impact of the charged particles on the surface produces gaseous ions of material originally present on the surface. The resulting mass spectra are similar to normal ESI mass spectra in that they show mainly singly or multiply charged molecular ions of the analytes. The DESI phenomenon was observed both in the case of conductive and insulator surfaces and for compounds ranging from nonpolar small molecules such as lycopene, the alkaloid coniceine, and small drugs through polar compounds such as peptides and proteins. Changes in the solution that is sprayed can be used to selectively ionize particular compounds, including those in biological matrices. In vivo analysis is demonstrated.

The present invention describes an improved commercial process for the production of carotenoid-cyclodextrin complexes and formulation of the complex for human ingestion. Complexation with cyclodextrins (e.g., α-cyclodextrin, β-cyclodextrin, γ-cyclodextrin, or HP-β-cyclodextrin) significantly improves the uptake of carotenoids (e.g., lycopene, lutein, or zeaxanthin) and their mixtures in vitro. The method for making such complexes includes forming a carotenoid / cyclodextrin complex; freezing drying said carotenoid / cyclodextrin complex; and blending said freeze-dried carotenoid / cyclodextrin complex with a mixture of lecithin and a vegetable oil or a vegetable oil suitable for soft gelatin capsules. The cyclodextrin / carotenoid complex can be formed in a molar ratio of between about 0.5:1.0 and 10:1. In vivo, in a human study, the lutein / γ-cyclodextrin complex formulated in lecithin-oil or oil showed a better absorption of lutein, as compared to the free lutein-oil formulation.

The present invention is directed to carotenoid-containing compositions and methods for improving bone or respiratory health in a subject comprising administering to the subject a combination of lycopene, beta-carotene, and beta-cryptoxanthin.

The invention relates to a method for preparing lycopene microcapsule, belonging to food engineering technique. It comprises following steps: (1) putting compound emulsifier and water into solid lycopene powder, grinding in ball grinder to form emulsion; (2) dissolving wall material into water, stirring and getting wall material solution; (3) mixing said lycopene emulsion with wall material, homogenizing with colloid mill; (4) spray drying homogenized mixing liquid and getting lycopene microcapsule. The invention is characterized by simple process, no organic solvent residual, high productivity, and suitability for large production. The produced lycopene microcapsule is characterized by sphere shape, pink color, homogenous granular size, smooth surface, no smelly odor, good fluidity, good water solubility, high content of lycopene, restoration at normal temperature and packed with polyethylene film bag of 0.2mm, and long storage period of more than 4 months.

A dietary supplement is created, comprised of material from the following nutrients, vitamins, herbs, minerals, and food and plant substances and food and plant derivatives: lycopene, vitamin E, selenium, green tea, coenzyme Q10, garlic, folic acid, vitamin C, curcumin, seaweed, Cordyceps sinsensis mushroom, Lentinus edodes (shiitake) mushroom, and Ganoderma lucidum (reishi) mushroom. The composition is administered orally for individuals who wish to reduce their risk of disease, particularly cancer-risk.

The invention relates to the technical field of genetic engineering, and discloses a recombinant yeast strain as well as a construction method and an application thereof. The recombinant yeast strain has the knockout gene gal1, gal7, gal10 or gal80, and the knockout gene ypl062w, and contains 2-4 gene segments integrated to the genome through the yeast homologous recombination. According to the invention, the yeast strain with the knockout genes is established, an optimized host cell is provided for producing lycopene, and functional genes crtE, crtB and crt I with different sources for synthetizing lycopene, and the specific yeast endogenous genes are selected, and integrated to the genome of the yeast strain with the knockout gene through the modular design, and thus a brand-new recombinant strain with high yield of lycopene is obtained.

The invention relates to a preparation method for stable water soluble carotenoid dry powder, the organic solvent of acetone or isopropanol dissolved with carotenoid component is added into an aqueous phase solvent containing a surfactant and adjuvant-stabilization component to be sufficiently mixed under sufficient stirring, then the organic solvent in the mixed solvent is removed and an auxiliary forming accessory which is one to twelve times of the carotenoid component by mass is added to be evenly stirred and treated with sponging frying to obtain the powder product. The preparation method is simple and easy, complex operation such as high pressure homogenization is not needed, and the procedures are less, therefore, the method is applicable to various carotenoid components containing Beta-carotene, astaxanthin, lutein, corn pigment and lycopene, etc. The method has the advantages that the performance of the products is good, the grain diameter of the powder product can be in the range of 90 to 170 nm, and the product can be evenly dispersed in water and form a stable and transparent carotenoid water dispersoid solvent.

The invention relates to the technical field of gene engineering, and discloses a recombinant yeast strain, and a construction method and application thereof. In the recombinant yeast strain, gal1, gal7, gal10 and ypl062w genes are knocked out, and the recombinant yeast strain comprises 9 gene segments which are integrated to the genome by yeast homologous recombination. The construction method comprises the following steps: constructing a four-knock-out yeast strain to provide an optimized host cell for producing beta-carotin, selecting lycopene cyclases crtY from different sources, and carrying out modular design to integrate functional genes crtE crtB and crtI of the specific-source synthetic lycopene, specific yeast endogenous genes and the like to the four-knock-out yeast strain genome, thereby obtaining a brand-new recombinant strain capable of producing beta-carotin at high yield.

A method for quickly extracting lycopene belongs to the technical field of food ingredients. The present invention extracts lycopene from raw materials rich in lycopene. After preliminary treatment of the raw materials rich in lycopene, ultrasonic / microwave collaborative technology is used to assist solvent reflux to extract lycopene, and the lycopene oleoresin is obtained after concentration. products; and recover solvents. The method of the invention has simple steps, greatly shortens the extraction time, and avoids the loss of lycopene during the extraction process; the extraction rate is high, and the highest extraction rate can reach 97%; the extraction process adopts a closed system, consumes less solvent, reduces costs, and at the same time increases It ensures the safety of production; using microwave as the heating source, the energy directly acts on the extraction system, reducing the waste of energy and having the characteristics of energy saving.

The invention discloses a beta-carotene micro-capsule and the preparation method thereof. The beta-carotene comprises one of lycopene, lutein, zeaxanthin and astaxanthin or the mixture thereof, belonging to the fields of drugs and health care products. The beta-carotene micro-capsule is composed of the following raw materials by weight proportions: beta-carotene: lipid material: capsule material: emulsifier: water equals to 1:1-20:1-20-1-10:80-100. The invention adopts a two-phase emulsion spray drying method to prepare the beta-carotene micro-capsule, which has good light and thermal stability and water-solubility or water dispersivity.

The invention provides a method for brewing a yellow wine using enzyme preparation and multi-bacteria, characterized in that: the concrete steps are that: soaking glutinous rice in clean water and adding lipase; steaming the glutinous rice and cooling, and adding alpha-amylase and neutral protease into the mixture and incubating and liquefying the mixture; adjusting the pH of mash and adding acid-resistant glucoamylase and incubating, saccharifying and cooling the mixture; adding bran koji, saccharomyces cerivisiae, ester-producing yeast and saccharifying and fermenting the mixture until the alcohol content is 12 degrees; continuously fermenting the mixture until the alcohol content is larger than 15 degrees and squeezing and filtering the mixture; adding stachyose, oligoisomaltose, honey,medlar leach solution and lycopene antioxidant into the filtered solution; processing the above mixture using a microwave alcoholic ripening machine and adding diatomite absorbent into the mixture and quickly freezing the mixture to clarify the mixture and then using a diatomite filter machine to filter the mixture and finally using membrane micro-straining technology to strain and degerm the product. The advantages of the invention are that: the wine taste is rich and strong; the wine body is full and soft and the wine is a health-care wine capable of adjusting the micro-ecological balance of the human digestive system.

The invention relates to the field of medical preparations, in particular to an enteric solid preparation containing lycopene, resveratrol or melatonin and a preparation method of the enteric solid preparation. The enteric solid preparation comprises one or more of lycopene, resveratrol and melatonin as an active ingredient, water-soluble and / or enteric carrier adjuvants or other pharmaceutic adjuvants. The water-soluble carrier adjuvants can be used as water-soluble solid dispersoid carriers; and the enteric carrier adjuvants are enteric polymers and can be used as enteric solid dispersoid carriers or enteric coating film materials. The lycopene, the resveratrol and the melatonin of the enteric solid preparation have favorable dissolubility in the intestinal tract, so that the medicament, namely, the enteric solid preparation, can be rapidly dissolved and released in the intestinal tract, and thus absorption and bioavailability of the lycopene, the resveratrol and the melatonin are increased. The enteric solid preparation containing the lycopene, the resveratrol and the melatonin can be suitable for application and industrial production of oral preparations, such as tablets, particles, pellets, capsules, enteric capsules, enteric coating tablets, enteric coating pellets, enteric coating particles and the like.

According to the present invention, fat and caloric content of processed cheeses can be reduced by the replacement of a portion fat content normally found in processed cheeses with an equal amount of emulsified liquid shortening composition comprising dietary fiber gel, water and lipid. The result is that fat and caloric content of processed cheeses can be manipulated with minimal effect on taste and texture. Furthermore, these emulsified mixtures, or “emulsified liquid shortening compositions comprising dietary fiber gel, water and lipid”, can further comprise functional foods such as high omega three and omega six oils and pure omega three and omega six fatty acids, medium chain triglyceride, beta carotene, calcium estearate, vitamin E, bioflavonoids, fagopyritrol, polyphenolic antioxidants of vegetable origin, lycopene, luteine and soluble fiber, for example Beta-Glucan derived from yeast, and other soluble fibers derived from grain, flax seed, and other vegetable and fruit fiber sources, and any combination thereof. Hence, in addition to reducing fat and caloric content of processed cheeses, further health benefits can be achieved by replacing a portion of fat with emulsified liquid shortening compositions comprising dietary fiber gel, water and lipid.

This invention is directed to a multi-vitamin and mineral supplement tailored to men and post-menopausal women, pre-menopausal women, and athletes which supplies the right amount of the right micronutrients at the right time to assure adequate intake of micronutrients needed for disease prevention and protection against nutritional losses and deficiencies due to lifestyle factors and common inadequate dietary patterns. The multi-vitamin and mineral supplement is comprised of vitamin A, vitamin C, vitamin D, vitamin E, vitamin K, vitamin B1, vitamin B2, niacinamide, vitamin B6, vitamin B12, biotin, pantothenic acid, iron, iodine, magnesium, zinc, selenium, copper, chromium, potassium, choline, lycopene, and co-enzyme Q-10.

The invention belongs to the fields of animal nutrition and feed science, relates to a diet preparation technique for the production of functional mutton which is rich in lycopene and conjugated linoleic acid (CLA) by mutton sheep, and is applicable to mutton sheep at the fattening period. The diet comprises the following raw materials: corn, tomato pomace, soybean meal, cotton meal, wheat bran, sunflower meal, corn stalk, and the like. Because tomato pomace that is rich in lycopene and linoleic acid is added into the diet, not only the mutton produced by the mutton sheep at the fattening period contains lycopene, but also the content of conjugated linoleic acid (CLA) in the mutton is increased, which can enhance mutton sheep immunity and reduce feed cost.

The invention relates to the technical field of gene engineering, and discloses a recombinant yeast strain, and a construction method and an application thereof. The recombinant yeast strain is obtained through the following steps: knocking out gal1, gal7, gal10 and ypl062w genes, integrating three gene fragments a genome through yeast homologous recombination, further knocking out an rox1 gene, and further integrating two gene fragments to the yeast genome. The gene knockout yeast strain constructed in the invention provides optimized host cells for production of lycopene; and combined functional genes crtE, crtB and crtI having specific sources and used for synthesizing the lycopene and specific yeast endogenous genes are selected and are integrated to the gene knockout strain genome through modular designing, so the brand new recombinant strain for highly yielding lycopene is obtained.

The invention discloses comprehensive nutrition powder and a preparation method thereof. The comprehensive nutrition powder is characterized by comprising the following raw materials: vitamin B1, vitamin B2, vitamin B6, pantothenic acid, vitamin B12, vitamin C, vitamin A, vitamin K, vitamin D, vitamin E, biotin, folic acid, calcium, magnesium, iron, zinc, selenium, chromium, copper, manganese, corn fiber flour, inulin, soy isolate protein powder, black bean peel extract, Agaricus blazei Murill extract, soya bean lecithin, phaseolus calcaratus extract, L-carnitine, beta carotene, lycopene, citrus extract, vanadium, acerola cherry extract, grape seed extract, maltodextrin, essence, aspartame and acesulfame. The comprehensive nutrition powder refers to a rich nutrition food which is researched directionally, can be highly matched with low sugar diet and fitting exercise to form a conditioning scheme which specially aims at treating obesity and three highs, can achieve a comprehensive and obvious rehabilitation effect of weight loss and reduction of three highs, and is easy to popularize in a large scale.

A dietary supplement including a unique combination of fruits, vegetables, herbs, and optionally vitamins, minerals and specialty ingredients. The supplement can include a fruit ingredient, a vegetable ingredient and an herbal ingredient, wherein the fruit ingredient is at least one of pomegranate and citrus bioflavonoids, wherein the vegetable ingredient is at least one of asparagus, lutein, lycopene and watercress, and wherein the herbal ingredient is at least one of basil, oregano and rosemary. The supplement can be administered to subjects to correct a dietary deficiency of phytochemicals and other nutrients, improve the amount of antioxidants in the subject, and decrease free radical damage in the subject.

The invention discloses a production method of lycopene microcapsule, providing a production method for realizing lycopene encapsulated emulsion by spray drying on the basis of the physical and chemical properties of lycopene. The method comprises the following steps: blending wall material solution, blending core material solution, homogenizing after the core material solution is mixed with the wall material solution, carrying out spray drying on emulsion, measuring lycopene microcapsule solubility, carrying out stability test and the like. Preferably, the preparation step of the lycopene microcapsule also comprises: an ultrasound assisted high-pressure homogenizing method is adopted to prepare the emulsion; and homogenized emulsion is performed with spray drying to obtain the lycopene microcapsule which has high solubility and favorable stability for light, heat and oxygen.

The process of extracting and separating lycopene from tomato includes the steps of: preparing tomato dry powder; filling tomato dry powder to ensure the flow and homogeneous distribution of supercritical CO2; starting extracting and separating device and regulating the flow rate of CO2 and entrainer and pressure in the two stage separator; extracting and separating lycopene continuously at flowing supercritical CO2 condition; and discharging product. The present invention has high extracting and separating speed, high extracting efficiency, high purity of separated product, low running cost and no pollution.

The invention discloses a solid dispersion of beta-carotene and the preparation method thereof. The beta-carotene comprises one of lycopene, lutein, zeaxanthin and astaxanthin or the random mixture of the materials, belonging to the fields of drugs and health care products. The solid dispersion of beta-carotene is composed of the following raw materials by preferred weight proportions: beta-carotene: polymer: additive equals to 1:3-10:0-5. The invention adopts a melting method and a solvent method to prepare the solid dispersion of beta-carotenen, which has good light and thermal stability and water-solubility or water dispersivity. The products can be prepared into tablets, capsules, pills, oral intake liquid and beverages.

The invention discloses a preparation method of multi-functional and lycopene-contained edible oil, which is simple in technique and can greatly improve the lycopene content in a cis structure and can result in a plurality of alimentary and sanitarian matters in the edible oil. The preparation method of the invention comprises the following steps: (I) firstly, oxidative factors removing: under inert gas atmosphere, removing the air or volatile impurities in the edible oil that can result in oxidation; (II) then, adding lycopene and at the same time heating to 100-200 DEG C, until the lycopene and the edible oil mixing evenly, and then cooling to the normal temperature; (III) adding other required alimentary and sanitarian matters after being cooled to the normal temperature. The edible oil prepared is well suitable for the Chinese food habits, the lycopene in which can be effectively absorbed by human body in the routine diet, so that people can fully utilize a plurality of functions of lycopene, such as antioxidant capacity, free radicals scavenging capacity and repairing cells, anti-aging, anticancer and cancer prevention and so on, thus makes positive effects to the health of human body.

The invention discloses an anti-aging cosmetic composition containing lycopene. The cosmetic composition is prepared from an oil phase composed of one or more oily components and lycopene, a mixed emulsifier composed of one or more emulsifiers and water, wherein the ratio of the mass of lycopene to the total mass of the oily components is (0.1-5):1,000, an HLB value of the mixed emulsifier is a weighted mean value of HLB values of all the emulsifiers composing the mixed emulsifier, the value taking interval of the HLB value of the mixed emulsifier is 8-18, and the mass ratio of the oil phase to the mixed emulsifier is 1:(0.05-1). According to the anti-aging cosmetic composition, all the ingredients are matched according to a specific proportion, the free radical scavenging capacity of lycopene can be fully achieved, after lycopene is percutaneously absorbed, excessive accumulation of free radicals can be fundamentally inhibited, and an anti-oxidant system of the skin is enhanced, so that aging is delayed.