23 results about "Cryptoxanthin" patented technology

The invention discloses a preparation method of a high-quality capsicum orange pigment. The preparation method comprises the following steps: drying and crushing pigment peppers, and then carrying out carbon dioxide supercritical extraction to obtain a gas phase and a liquid phase; introducing the gas phase into a separation kettle, and separating to obtain a liquid-phase substance containing capsicum orange pigment; and discharging the pressure in the extraction kettle to obtain a liquid phase as a capsanthin product. The yield of the obtained capsicum orange is 3.22%, the color value yield is 97.01%, and lambda is 0.8312; the content of carotenoid is 0.11%; the total organic content is less than 50ppm; the content of (zeaxanthin, beta-cryptoxanthin and beta carotene) is 90.62%; and the capsaicin content is 0.0009%.

The invention discloses application of a lycium barbarum Lb03G03224 gene in catalysis of esterification of free carotenoids, the nucleotide sequence of the lycium barbarum Lb03G03224 gene is as shown in SEQ ID NO: 1, and the amino acid sequence of encoded protein is as shown in SEQ ID NO: 2. According to the present invention, it is found that the zeaxanthin dipalmitate and the isomer 9 (Z)-zeaxanthin dipalmitate thereof can be generated when the Lb03G03224 gene is expressed in the engineering escherichia coli for generating beta-carotene, beta-cryptoxanthin and zeaxanthin, such that the zeaxanthin dipalmitate and the isomer 9 (Z)-zeaxanthin dipalmitate can be produced, the protein coded by the Lb03G03224 has the function of catalyzing esterification reaction of carotenoid containing free hydroxyl and fatty acid acyl donor, and has important application value in in-vitro biosynthesis of esterified carotenoid.

A capsicum annum extract composition (600) includes capsanthin in the range from 1%-1.5%, zeaxanthin in the range from 0.5% to 1%, and cryptoxanthin in the range from 0.1% to 0.5%. The composition is created, at least in part, from material spent from purifying carotenoids using counter current extractions, and the composition enhances skin, eyes, or hair.

The application discloses application of cryptoxanthin in preparation of a combination drug for treating lenalidomide-resistant multiple myeloma, and relates to the technical field of medicines.The application verifies the effect and potential mechanism of betaCRY in treating LEN-resistant MM through in-vivo and in-vitro experiments, specifically, betaCRY can inhibit the expression level of FSP1 protein in LEN-resistant tumors, thereby inducing the occurrence of ferroptosis, and then significantly reducing the activity of LEN-resistant tumor cells, and finally achieving the purpose of overcoming LEN tumor drug resistance.The discovery in the application proves that a plant extract serves as a new FSP1 inhibitor in the treatment of LEN-resistant MM cells, and provides a theoretical basis for further using betaCRY to treat LEN-resistant MM in clinic.Therefore, the application has a good application prospect in the field of treating drug-resistant MM.

Invention deals with a macular carotenoid formulation comprising Carotenoids, Lutein, Zeaxanthin, Meso Zeaxanthin, Beta Carotene, Alpha Carotene, Lycopene and Cryptoxanthin in a synergistic combination. The formulation helps in increasing macular pigment optical density (MPOD) related to prevention of age-related macular degeneration (ARMD). The formulation is used as a nutrient, nutraceutical or dietary supplement. The dietary supplement may be formulated as soft gel capsules, two-piece hard-shell capsules, liquid-fill capsules, tablets, effervescent granules, gummies, powder mixes, stick packs, beverages, emulsions, bakery products, dairy products, tinctures, oil suspensions, beadlets, powders, cold water-soluble powders, emulsions and granules or any combination thereof. The present invention can be used for the development of functional food, dietary plan and as a nutritional supplement. In exemplary embodiment, formulation is available in forms like oil suspension, beadlets, powders, cold water-soluble powders, emulsions and granules.

The present invention relates to a novel method for isolating capsanthin and several other carotenoids from paprika oleoresin, a concentrated extract of paprika fruit (Capsicum annuum). In another aspect, the invention relates to the use of mild non-aqueous and aqueous saponification methods for isolating highly pure capsanthin and other carotenoids from paprika oleoresin at temperatures of about 20-50°C. In another aspect, the invention relates to a saponification method that results in a crystalline mixture of capsanthin, β-carotene, β-cryptoxanthin, and zeaxanthin, which can be separated by solvent extraction and crystallization to obtain highly pure capsanthin and other carotenoids.

This invention belongs to the field of citrus cultivation technology, specifically relating to a method for increasing the β-cryptoxanthin content in mandarin oranges through artificial lighting. This invention involves applying specific wavelengths of artificial lighting to fully mature mandarin orange trees, including Satsuma mandarins, during the period from late September (Autumn Equinox) to the harvest season when natural daylight hours are shorter. This effectively increases the β-cryptoxanthin content in mandarin oranges. Furthermore, the method described in this invention is simple, easy to implement, low-cost, and suitable for widespread application.

To provide an oral composition which comprises at least one carotenoid selected from the group consisting of capsanthin, β-cryptoxanthin, zeaxanthin, and β-carotene and has an excellent bone resorption-inhibiting action.SOLUTION: There is provided an oral composition which comprises at least one carotenoid selected from the group consisting of capsanthin, β-cryptoxanthin, zeaxanthin, and β-carotene and a black ginger (Kaempferia parviflora) extract.SELECTED DRAWING: None

The invention relates to the technical field of molecular markers, in particular to an SNP molecular marker related to the beta-cryptoxanthin content character of sweet corn and application of the SNP molecular marker. High performance liquid chromatography is used for detecting the beta-cryptoxanthin content character of the sweet corn kernels, QTL positioning is conducted through the beta-cryptoxanthin content character of the kernels, it is found that one major QTL related to the beta-cryptoxanthin content of the sweet corn kernels exists on the sixth chromosome of the corn, the major QTL is between SNP loci Chr677689205 and Chr682556175, and the major QTL can be used for detecting the beta-cryptoxanthin content of the sweet corn kernels. The SNP locus Chr677988878 has the advantages that the phenotype contribution rate of the SNP locus Chr677988878 to the content of the beta-cryptoxanthin in the corn kernels is 17.04%, the SNP locus Chr677988878 is closely linked with the content of the beta-cryptoxanthin in the corn kernels, the SNP locus can be used for predicting the content of the beta-cryptoxanthin in the sweet corn kernels, and technical support is provided for molecular marker-assisted breeding.

The invention discloses yarrowia lipolytica genetically engineered bacteria for producing lutein as well as a construction method and application of the yarrowia lipolytica genetically engineered bacteria. According to the invention, the Cu < 2 + > induced promoter pMT2 is introduced, and the lycopene is differentially regulated on the time scale to carry out epsilon-cyclization reaction and beta-cyclization reaction, so that the content of by-product beta-carotene is greatly reduced; by introducing a cipB scaffold protein strategy, a high-efficiency electron transport protein complex for converting alpha-carotene into xanthophyll is constructed, and the content of an intermediate product alpha-cryptoxanthin is effectively reduced; by introducing a synthetic route of cytochrome P450 monooxygenase cofactor heme, the activity of a key catalytic enzyme is improved, and the yield of xanthophyll is effectively improved. The Yarrowia lipolytica engineering strain can utilize common carbon sources and nitrogen sources, the shake flask yield of xanthophyll can reach 93 mg / L after fermentation culture, and the Yarrowia lipolytica engineering strain is an excellent strain with high xanthophyll yield and has great industrial application prospects.

To provide an oil-soluble pigment emulsified preparation which uses alkenylsuccinic acid esterified starch having high emulsion stability and color tone stability during storage.SOLUTION: An oil-soluble pigment preparation is an oil-in-water type emulsified composition including an aqueous phase containing alkenylsuccinic acid esterified starch and a water-soluble polysaccharide, and an oil phase containing an oil-soluble pigment, where a pH of the aqueous phase is 3.5 or lower. The oil-soluble pigment desirably includes xanthophylls such as astaxanthin, capsanthin, canthaxanthin, cryptoxanthin, zeaxanthin, fucoxanthin, lutein, capsicum pigment (alternatively: paprika pigment), marigold pigment, orange pigment, phaffia pigment, and haematococcus algae pigment.SELECTED DRAWING: None

The invention discloses application of cryptoxanthin in preparation of a combined medicine for treating lenalidomide-resistant multiple myeloma, and relates to the technical field of medicines. The effect and potential mechanism of the beta CRY in treating LEN drug-resistant MM are verified through in-vivo and in-vitro experiments, specifically, the beta CRY can induce ferroptosis by inhibiting the expression level of FSP1 protein in LEN drug-resistant tumors, then the activity of LEN drug-resistant tumor cells is remarkably reduced, and finally the purpose of overcoming LEN tumor drug resistance is achieved. The discovery in the invention proves the treatment effect of the plant extract as a novel FSP1 inhibitor in LEN drug-resistant MM cells, and provides a theoretical basis for further clinical treatment of LEN drug-resistant MM by using beta CRY. Therefore, the invention has a good application prospect in the field of treatment of drug-resistant MM.

A Capsicum annum extract composition (600) includes capsanthin in the range from 50% to 80%, zeaxanthin in the range from 5% to 15%, and cryptoxanthin in the range from 1% to 5%.

This method for confirming nutrient attenuation of a frozen food is characterized by including a step for performing an acceleration test on a frozen food at a temperature of 0°C or higher and under a high-pressure condition of 90 MPa or greater, and a step for analyzing nutrients contained in the frozen food subjected to the acceleration test. The method is further characterized in that the nutrient to be confirmed is at least one of retinol, α-carotene, β-carotene, β-cryptoxanthin, vitamin D, α-tocopherol, vitamin K, vitamin B1, vitamin B2, niacin, vitamin B6, vitamin B12, folic acid, pantothenic acid, biotin, vitamin C, n-3-based polyunsaturated fatty acids, and n-6-based polyunsaturated fatty acids.

The invention belongs to the technical field of citrus planting, and particularly relates to a method for increasing the content of beta-cryptoxanthin in broad-peel citrus through artificial light supplement. According to the method, under the condition that the natural sunshine time is shortened from the last ten-day period of September (the solar term of autumn equinox) to the harvesting period every year, facility full-ripening cultivation broad-peel citrus trees including satsuma oranges are subjected to light supplementing treatment of a specific wavelength type, and the content of beta-cryptoxanthin in the broad-peel citrus can be effectively increased; the cost is low.

The invention relates to the technical field of bioengineering, in particular to application of a ZNF451 expression inhibitor in preparation of a cis-platinum drug-resistant osteosarcoma drug. The invention provides an application of a ZNF451 expression inhibitor in preparation of a cis-platinum drug-resistant osteosarcoma drug. The cis-platinum drug-resistant osteosarcoma drug comprises the ZNF451 expression inhibitor. The key effect of SUMO E3 ligase ZNF451 in osteosarcoma drug resistance is determined for the first time, and a traditional Chinese medicine active component beta-cryptoxanthin with a function of selectively inhibiting ZNF451 is found. The component not only can have a synergistic effect with cis-platinum to reverse the cis-platinum resistance of osteosarcoma, but also provides a new target site and a molecular marker for clinically predicting and improving the treatment effect of a patient. The innovative strategy brings a new hope for osteosarcoma treatment, and particularly provides a more effective solution for the problem of cis-platinum drug resistance.

The invention belongs to the technical field of food detection, and discloses a method for simultaneously detecting various carotenoids in egg yolk. According to the method, the C30 reversed-phase chromatographic column is creatively adopted, and an optimized binary mobile phase gradient elution procedure is combined, so that the problem of co-elution of structural analogues (especially lutein and zeaxanthin) is successfully solved. The method provided by the invention realizes simultaneous baseline separation of five main carotenoids, namely lutein, zeaxanthin, cantharidin yellow, beta-cryptoxanthin and beta-carotene, peak shapes are sharp and symmetrical, the separation degree is obviously superior to that of a traditional C18 chromatographic column method, and a solid foundation is laid for accurate quantification.

A Capsicum annum extract composition (600) includes capsanthin in the range from 50% to 80%, zeaxanthin in the range from 5% to 15%, and cryptoxanthin the range from 1% to 5%.

The present invention relates to a novel process for the isolation of capsorubin and several other carotenoids from capsicum oleoresin, which is a concentrated extract of capsicum fruit (Capsicum annuum). In another aspect, the present invention relates to the use of mild non-aqueous saponification processes and aqueous saponification processes for separating high purity capsorubin and other carotenoids from capsicum oleoresins at temperatures of about 20 DEG C to 50 DEG C. In another aspect, the present invention relates to a saponification process that produces a crystalline mixture of capsorubin, beta-carotene, beta-cryptoxanthin and zeaxanthin, which can be separated by solvent extraction and crystallization to provide high purity capsorubin as well as other carotenoids.

The capsicum extract composition (600) comprises capsanthin in the range of 1-1.5%, zeaxanthin in the range of 0.5-1%, and cryptoxanthin in the range of 0.1-0.5%. The composition is produced, at least in part, from materials consumed from purifying carotenoids using countercurrent extraction, and the composition is for strengthening the skin, eyes, or hair.

The method for confirming nutrient attenuation in frozen food according to the present invention is characterized by comprising: a step for performing an accelerated test on frozen food at a temperature of 0 DEG C or more and a high pressure of 90 MPa or more; and a step for analyzing the nutrients contained in the frozen food after the accelerated test. The method is also characterized in that the nutrient to be confirmed is at least one of the following: retinol, alpha-carotene, beta-carotene, beta-cryptoxanthin, vitamin D, alpha-tocopherol, vitamin K, vitamin B1, vitamin B2, nicotinic acid, vitamin B6, vitamin B12, folic acid, pantothenic acid, biotin, vitamin C, n-3 polyunsaturated fatty acids and n-6 polyunsaturated fatty acids.

The present application relates to the technical field of molecular markers, in particular to a SNP molecular marker related to the beta-cryptoxanthin content trait of sweet corn and application thereof. The present application detects the beta-cryptoxanthin content trait of sweet corn kernels by using high performance liquid chromatography, and positions QTL by using the beta-cryptoxanthin content trait of kernels, finds that there is one major QTL related to the beta-cryptoxanthin content of sweet corn kernels on the 6th chromosome of corn, which is between SNP sites Chr6_77689205 and Chr6_82556175, and the contribution rate of the QTL to the beta-cryptoxanthin content phenotype of kernels is 17.04%, the SNP site Chr6_77988878 is closely linked to the beta-cryptoxanthin content of kernels, and the SNP site can be used for predicting the beta-cryptoxanthin content of sweet corn kernels, and provides technical support for molecular marker assisted breeding.

The invention provides an application of cryptoxanthin in treating acute lung injury, and belongs to the technical field of application of cryptoxanthin. The invention provides an application of Cryptoxanol in treatment of acute lung injury, the Cryptoxanol can be used independently or combined with other medicinal components for use, and can be prepared into tablets, capsules, electuary, drops, granules or injections for use. The Cryptotaxol can be applied to treatment of acute lung injury, a theoretical research basis is provided for application of Cryptotaxol to treatment of acute lung injury, and meanwhile, verification is further carried out by adopting mouse experiments, and theoretical and experimental basis is provided for clinical research.