12 results about "Cryptoxanthin" patented technology

The invention discloses application of a lycium barbarum Lb03G03224 gene in catalysis of esterification of free carotenoids, the nucleotide sequence of the lycium barbarum Lb03G03224 gene is as shown in SEQ ID NO: 1, and the amino acid sequence of encoded protein is as shown in SEQ ID NO: 2. According to the present invention, it is found that the zeaxanthin dipalmitate and the isomer 9 (Z)-zeaxanthin dipalmitate thereof can be generated when the Lb03G03224 gene is expressed in the engineering escherichia coli for generating beta-carotene, beta-cryptoxanthin and zeaxanthin, such that the zeaxanthin dipalmitate and the isomer 9 (Z)-zeaxanthin dipalmitate can be produced, the protein coded by the Lb03G03224 has the function of catalyzing esterification reaction of carotenoid containing free hydroxyl and fatty acid acyl donor, and has important application value in in-vitro biosynthesis of esterified carotenoid.

The application discloses application of cryptoxanthin in preparation of a combination drug for treating lenalidomide-resistant multiple myeloma, and relates to the technical field of medicines.The application verifies the effect and potential mechanism of betaCRY in treating LEN-resistant MM through in-vivo and in-vitro experiments, specifically, betaCRY can inhibit the expression level of FSP1 protein in LEN-resistant tumors, thereby inducing the occurrence of ferroptosis, and then significantly reducing the activity of LEN-resistant tumor cells, and finally achieving the purpose of overcoming LEN tumor drug resistance.The discovery in the application proves that a plant extract serves as a new FSP1 inhibitor in the treatment of LEN-resistant MM cells, and provides a theoretical basis for further using betaCRY to treat LEN-resistant MM in clinic.Therefore, the application has a good application prospect in the field of treating drug-resistant MM.

This invention belongs to the field of citrus cultivation technology, specifically relating to a method for increasing the β-cryptoxanthin content in mandarin oranges through artificial lighting. This invention involves applying specific wavelengths of artificial lighting to fully mature mandarin orange trees, including Satsuma mandarins, during the period from late September (Autumn Equinox) to the harvest season when natural daylight hours are shorter. This effectively increases the β-cryptoxanthin content in mandarin oranges. Furthermore, the method described in this invention is simple, easy to implement, low-cost, and suitable for widespread application.

To provide an oral composition which comprises at least one carotenoid selected from the group consisting of capsanthin, β-cryptoxanthin, zeaxanthin, and β-carotene and has an excellent bone resorption-inhibiting action.SOLUTION: There is provided an oral composition which comprises at least one carotenoid selected from the group consisting of capsanthin, β-cryptoxanthin, zeaxanthin, and β-carotene and a black ginger (Kaempferia parviflora) extract.SELECTED DRAWING: None

The invention relates to the technical field of molecular markers, in particular to an SNP molecular marker related to the beta-cryptoxanthin content character of sweet corn and application of the SNP molecular marker. High performance liquid chromatography is used for detecting the beta-cryptoxanthin content character of the sweet corn kernels, QTL positioning is conducted through the beta-cryptoxanthin content character of the kernels, it is found that one major QTL related to the beta-cryptoxanthin content of the sweet corn kernels exists on the sixth chromosome of the corn, the major QTL is between SNP loci Chr677689205 and Chr682556175, and the major QTL can be used for detecting the beta-cryptoxanthin content of the sweet corn kernels. The SNP locus Chr677988878 has the advantages that the phenotype contribution rate of the SNP locus Chr677988878 to the content of the beta-cryptoxanthin in the corn kernels is 17.04%, the SNP locus Chr677988878 is closely linked with the content of the beta-cryptoxanthin in the corn kernels, the SNP locus can be used for predicting the content of the beta-cryptoxanthin in the sweet corn kernels, and technical support is provided for molecular marker-assisted breeding.

The invention discloses yarrowia lipolytica genetically engineered bacteria for producing lutein as well as a construction method and application of the yarrowia lipolytica genetically engineered bacteria. According to the invention, the Cu < 2 + > induced promoter pMT2 is introduced, and the lycopene is differentially regulated on the time scale to carry out epsilon-cyclization reaction and beta-cyclization reaction, so that the content of by-product beta-carotene is greatly reduced; by introducing a cipB scaffold protein strategy, a high-efficiency electron transport protein complex for converting alpha-carotene into xanthophyll is constructed, and the content of an intermediate product alpha-cryptoxanthin is effectively reduced; by introducing a synthetic route of cytochrome P450 monooxygenase cofactor heme, the activity of a key catalytic enzyme is improved, and the yield of xanthophyll is effectively improved. The Yarrowia lipolytica engineering strain can utilize common carbon sources and nitrogen sources, the shake flask yield of xanthophyll can reach 93 mg / L after fermentation culture, and the Yarrowia lipolytica engineering strain is an excellent strain with high xanthophyll yield and has great industrial application prospects.

The invention discloses application of cryptoxanthin in preparation of a combined medicine for treating lenalidomide-resistant multiple myeloma, and relates to the technical field of medicines. The effect and potential mechanism of the beta CRY in treating LEN drug-resistant MM are verified through in-vivo and in-vitro experiments, specifically, the beta CRY can induce ferroptosis by inhibiting the expression level of FSP1 protein in LEN drug-resistant tumors, then the activity of LEN drug-resistant tumor cells is remarkably reduced, and finally the purpose of overcoming LEN tumor drug resistance is achieved. The discovery in the invention proves the treatment effect of the plant extract as a novel FSP1 inhibitor in LEN drug-resistant MM cells, and provides a theoretical basis for further clinical treatment of LEN drug-resistant MM by using beta CRY. Therefore, the invention has a good application prospect in the field of treatment of drug-resistant MM.

A Capsicum annum extract composition (600) includes capsanthin in the range from 50% to 80%, zeaxanthin in the range from 5% to 15%, and cryptoxanthin in the range from 1% to 5%.

The invention belongs to the technical field of food detection, and discloses a method for simultaneously detecting various carotenoids in egg yolk. According to the method, the C30 reversed-phase chromatographic column is creatively adopted, and an optimized binary mobile phase gradient elution procedure is combined, so that the problem of co-elution of structural analogues (especially lutein and zeaxanthin) is successfully solved. The method provided by the invention realizes simultaneous baseline separation of five main carotenoids, namely lutein, zeaxanthin, cantharidin yellow, beta-cryptoxanthin and beta-carotene, peak shapes are sharp and symmetrical, the separation degree is obviously superior to that of a traditional C18 chromatographic column method, and a solid foundation is laid for accurate quantification.

A Capsicum annum extract composition (600) includes capsanthin in the range from 50% to 80%, zeaxanthin in the range from 5% to 15%, and cryptoxanthin the range from 1% to 5%.

The method for confirming nutrient attenuation in frozen food according to the present invention is characterized by comprising: a step for performing an accelerated test on frozen food at a temperature of 0 DEG C or more and a high pressure of 90 MPa or more; and a step for analyzing the nutrients contained in the frozen food after the accelerated test. The method is also characterized in that the nutrient to be confirmed is at least one of the following: retinol, alpha-carotene, beta-carotene, beta-cryptoxanthin, vitamin D, alpha-tocopherol, vitamin K, vitamin B1, vitamin B2, nicotinic acid, vitamin B6, vitamin B12, folic acid, pantothenic acid, biotin, vitamin C, n-3 polyunsaturated fatty acids and n-6 polyunsaturated fatty acids.

The present application relates to the technical field of molecular markers, in particular to a SNP molecular marker related to the beta-cryptoxanthin content trait of sweet corn and application thereof. The present application detects the beta-cryptoxanthin content trait of sweet corn kernels by using high performance liquid chromatography, and positions QTL by using the beta-cryptoxanthin content trait of kernels, finds that there is one major QTL related to the beta-cryptoxanthin content of sweet corn kernels on the 6th chromosome of corn, which is between SNP sites Chr6_77689205 and Chr6_82556175, and the contribution rate of the QTL to the beta-cryptoxanthin content phenotype of kernels is 17.04%, the SNP site Chr6_77988878 is closely linked to the beta-cryptoxanthin content of kernels, and the SNP site can be used for predicting the beta-cryptoxanthin content of sweet corn kernels, and provides technical support for molecular marker assisted breeding.