20 results about "Pyridoxine" patented technology

The application belongs to the technical field of molecular biology, and particularly relates to metabolic markers for distinguishing hypertrophic cardiomyopathy and left ventricular hypertrophy and application. The application analyzes the metabolome of hypertrophic cardiomyopathy (HCM) patients, left ventricular hypertrophy (LVH) patients caused by non-hypertrophic cardiomyopathy and healthy people, finds that carnitine C16:2, carnitine C14:0, carnitine C16:0, carnitine C18:0 and carnitine C18:1 are differentially expressed in HCM patients and LVH patients, pyridoxine phosphate, ito acid, adenosine monophosphate, adenosine diphosphate and adenosine triphosphate are differentially expressed in HCM patients and healthy people, lysine base, methyl glutamic acid, acetyl proline, malate semialdehyde and citramalate are differentially expressed in LVH patients and healthy people, and ROC curve analysis shows excellent prediction effect, strong specificity and high sensitivity.

The present disclosure provides compositions and methods for providing a health benefit to a growing animal comprising administering a food composition to the animal, wherein the food composition includes a brain development blend. The brain development blend generally comprises DHA, EPA, taurine, choline, thiamine, riboflavin, pantothenic acid, niacin, pyridoxine, vitamin B12, and folic acid.

The present invention aims to provide an oral composition that has an astringent sensation while effectively suppressing discoloration over time. [Solution] An oral composition comprising (A) component: pyridoxine or a salt thereof, (B) component: fluorine-containing compound, and (C) component: an anionic surfactant, wherein the content of component (B) is such that when converted to a fluoride ion concentration it is 1000 to 4000 ppm, and the content of component (C) is such that it is 0.05 to 5% by mass, preferably further comprising (D) component: at least one selected from the group consisting of saccharin sodium, sucralose, xylitol, erythritol, maltitol, acesulfame potassium, trehalose, and mannitol, and more preferably further comprising (E) component: at least one selected from the group consisting of tocopherol acetate and tocopherol nicotinate.

The present invention aims to provide a cosmetic containing a pyridoxine and having excellent stability and usability. The cosmetic of the present invention is characterized by comprising: (A) pyridoxine, a salt or a derivative thereof; (B) ethyl ascorbic acid; and (C) a higher fatty acid or a higher alcohol which is liquid at 25°C.

The present invention aims to provide an oral composition in which discoloration over time caused by pyridoxine or its salts is suppressed, and bitterness is reduced. [Solution] The present invention provides an oral composition comprising (A) component: pyridoxine or a salt thereof, and (B) component: a fluorine-containing compound, wherein the content of component (A) is 0.11 to 0.95% by mass, and the content of component (B) is such that when converted to a fluoride ion concentration, it is 1000 to 20000 ppm, and preferably further comprising (C) component: at least one sweetener selected from the group consisting of saccharin sodium, sucralose, xylitol, erythritol, maltitol, acesulfame potassium, trehalose, and mannitol.

The present invention provides an oral composition that can effectively suppress the bitter taste after use, even when pyridoxine or a salt thereof is used. [Solution] An oral composition comprising (A) component: pyridoxine or a salt thereof, and (B) component: inorganic powder, wherein the content of component (A) is 0.01% to 3% by mass, and the content of component (B) is 0.01% or more and less than 15% by mass.

A composition contains Nicotinamide and Vitamin B6, for example pyridoxine. The composition may be an oral nutritional composition, for example an infant formula, a follow up formula, a nutritional supplement, an oral nutritional supplement, a food product. The composition can be administered to an individual in need thereof for promoting muscle growth and / or for maintaining and / or increasing muscle function and / or muscle mass in infants and children. For example, the composition can be useful for increasing muscle function and / or muscle mass by modulating muscle stem cells.

This invention belongs to the field of enzyme engineering technology, specifically relating to an EcCAT mutant of catalase and its applications. The mutant is obtained by mutating at least one amino acid from the following positions in SEQ ID NO:1: Ile (126th position), Ser (167th position), Val (199th position), Gly (200th position), Asn (201st position), Phe (206th position), Ala (211th position), Phe (214th position), Gly (273rd position), Ala (389th position), Phe (391st position), Leu (407th position), and Gly (410th position). Compared to wild-type catalase, the EcCAT mutant of this invention exhibits higher catalytic efficiency. When used in combination with pyridoxine 5'-phosphate oxidase, the whole-cell catalytic synthesis of pyridoxal 5'-phosphate can be completed in just 5 hours, with a conversion rate exceeding 99%.

The present invention relates to a cocrystal of 1,1-dioxo-3,3-dibutyl-5-phenyl-7-methylthio-8-(N-{(R)-α-[N-((S)-1-carboxypropyl) carbamoyl]-4-hydroxybenzyl}carbamoylmethoxy)-2,3,4,5-tetrahydro-1,2,5-benzothiadiazepine (odevixibat) and pyridoxine. The invention also relates to a pharmaceutical composition comprising said cocrystal, and to its use in the treatment of various conditions as described herein.

FIELD: biotechnology.SUBSTANCE: modified composition of a nutrient medium for inducing the formation of soybean regenerated plants in vitro, including ammonium nitrate (NH4NO3) – 1650 mg / l; potassium nitrate (KNO3) – 1900 mg / l; calcium chloride dihydrate (CaCl2×2H2O) – 440 mg / l; magnesium sulfate (MgSO4×7H2O) – 370 mg / l; potassium phosphate (KH2PO4) – 170 mg / l; disodium salt of ethylenediaminetetraacetic acid (Na2 EDTA) – 37.3 mg / l; ferrous sulfate (FeSO4×7H2O) – 27.95 mg / l; boric acid (H3VO3) – 6.2 mg / l; manganese sulfate (MnSO4×4H2O) – 22.3 mg / l; zinc sulfate (ZnSO4×H2O) – 8.6 mg / l; sodium molybdate (Na2MoO4×2H2O) – 0.25 mg / l; copper sulfate (CuSO4×5H2O) – 0.025 mg / l; thionyl chloride (CoCl2×H2O) – 0.025 mg / l; agar-agar – 7000 mg / l, according to the invention the following components are additionally introduced: glycine – 1.0 mg / l; mesoinositol – 120 mg / l; ascorbic acid – 3.0 mg / l; nicotinic acid – 1.0 mg / l; pyridoxine-HCl – 1.5 mg / l; thiamine-HCl – 1.0 mg / l; biotin – 0.03 mg / l; sucrose – 25000 mg / l; 6-BAP – 1.0 mg / l; indole-butyric acid (IBA) – 1.5 mg / l; starch – 9000 mg / l; activated carbon – 3.0 mg / l; water is the rest.EFFECT: expanding the range of nutrient medium compositions for inducing the formation of soybean regenerated plants in vitro.1 cl, 3 tbl

To provide an oral composition that can suppress discoloration over time. [Solution] An oral composition comprising (A) component: pyridoxine or a salt thereof, and (B) component: a nonionic surfactant, wherein the content of component (A) is 0.01% by mass or more and less than 0.5% by mass, the content of component (B) is 0.01% or more and less than 1%, and the ratio of the content of component (B) to the content of component (A) ((B) / (A)) is 0.5 or more and less than 20.

The main purpose of the present inventors is to provide a technique for suppressing inflammation, in particular, in aging tissues within the oral cavity.　The present inventors have found that an oral composition containing at least one selected from the group consisting of β-glycyrrhetinic acid, glycyrrhizic acid, ascorbic acid, tocopherol nicotinate, tocopherol acetate, pyridoxine, cobalamin, retinol, retinol acetate, riboflavin, phylloquinone, calciferol, anthraquinone, menaquinone-4, and L-aspartic acid, and chemically acceptable salts thereof, quercetin, genistein, fisetin, nobiletin, kaempferol, apigenin, and naringenin, and glycosides thereof, and methyl hesperidin can suppress inflammation, in particular, in aging tissues within the oral cavity.

This invention discloses a recombinant bacterium for synthesizing pyridoxal phosphate, its construction method, and its applications. The encoding genes for pyridoxal kinase (PdxK) and pyridoxine oxidase (PdxH) are coupled to an ATP cycle and / or an oxygen cycle, and then introduced into mutant *E. coli* via a recombinant vector and / or gene substitution to construct the recombinant bacterium for pyridoxal phosphate synthesis. The recombinant bacterium can utilize less ATP as a cofactor, weakening the degradation pathways of pyridoxine and pyridoxal phosphate, effectively increasing the yield of pyridoxal phosphate and the conversion efficiency of pyridoxine / pyridoxine phosphate. The recombinant bacterium constructed using the method of this invention for producing pyridoxal phosphate has advantages such as low raw material costs, mild reaction conditions in the biotransformation method, simple process, and high production efficiency, and has good prospects for industrial application.

The present invention aims to provide a liquid oral composition that has an astringent sensation, effectively suppresses discoloration over time, and improves the sour taste during use. [Solution] The present invention relates to a liquid oral composition comprising (A) component: pyridoxine or a salt thereof, (B) component: glycerin, and (C) component: at least one selected from the group consisting of sorbitol, propylene glycol, and polyethylene glycol, wherein the ratio of the content (mass%) of component (B) to the content (mass%) of component (C) is less than 1, more preferably (D) component: a predetermined sweetener, and even more preferably (E) component: at least one selected from the group consisting of tocopherol acetate and tocopherol nicotinate.

The application belongs to the technical field of flame-retardant materials, and discloses a bio-based flame-retardant ultraviolet-resistant polyvinyl alcohol composite material and a preparation method thereof. The method is as follows: bio-based flame-retardant ultraviolet-resistant agent N,N'-bis(DOPO-pyridoxylmethyl) p-phenylenediamine (denoted as DPP) is prepared through Schiff base condensation and P-H nucleophilic addition reaction by taking pyridoxal phosphate, p-phenylenediamine and 9,10-dihydro-9-oxa-10-phospha-phenanthrene-10-oxide as raw materials, and the high-performance composite material is prepared by adding the bio-based flame-retardant ultraviolet-resistant agent into a polyvinyl alcohol system. In the composite material, the phosphorus-nitrogen active components released by thermal decomposition of DPP can quench gas phase combustion free radicals, and simultaneously catalyze dehydration and crosslinking of the polyvinyl alcohol matrix to form a continuous and dense carbon layer with high graphitization, so that gas-coagulation dual-phase synergistic flame retardation is realized; the aromatic conjugated structure endows the composite material with intrinsic excellent ultraviolet resistance; the strong hydrogen bonds between DPP and polyvinyl alcohol molecular chains construct a physical crosslinking network, which not only improves the crystallinity and thermal stability of the composite material, but also significantly enhances the mechanical properties.

To provide a toothpaste composition that can suppress discoloration over time. [Solution] A toothpaste composition comprising (A) component: pyridoxine or a salt thereof, and (B) component: one or more nonionic surfactants selected from the group consisting of polyoxyethylene hydrogenated castor oil, polyoxyethylene alkyl ether, polyglycerin fatty acid ester, alkyl glycoside, polyoxyethylene sorbitan fatty acid ester, sucrose fatty acid ester, sugar alcohol fatty acid ester, alkylolamide, fatty acid ethanolamide, sorbitan fatty acid ester, polyoxyethylene polyoxypropylene block copolymer, and polyoxyethylene polyoxypropylene fatty acid ester, wherein the content of component (A) is 0.01% by mass or more and less than 0.2% by mass.

This invention relates to the non-therapeutic use of one or more lipids for stimulating the gut microbiota to produce certain vitamins. The invention also relates to a nutritional supplement product comprising one or more lipids for stimulating the gut microbiota to produce certain vitamins. Lipids of particular interest are lauric acid (C12:0), oleic acid (C18:1), and linoleic acid (C18:2), and vitamins of particular interest are riboflavin and pyridoxine.

In a composition combining (A) pyridoxine salts, etc. and (B) heparinoids, the photostability of (A) pyridoxine salts, etc. is improved while maintaining the effect of improving the skin barrier function. [Solution] (A) One or more selected from the group consisting of pyridoxine, its derivatives and pharmaceutically acceptable salts thereof, (B) Heparin-like substances, and (C) Nicotinamide, A topical skin preparation composition containing [a specific ingredient].

The present application relates to a kind of production of Fermentation Medium of trichotoxin and a kind of fermentation method for improving the yield of trichotoxin, belong to biological fermentation technical field.The present application uses pea starch, glucose as carbon source, uses soybean meal, corn serum as nitrogen source, with suitable inorganic salt (sodium chloride, dipotassium hydrogen phosphate, potassium dihydrogen phosphate, ammonium sulfate, magnesium sulfate, sodium selenite), metabolic auxiliary factor (pyridoxine) and amino acid, prepare a kind of suitable for bacillus subtilis production trichotoxin Fermentation Medium, the cost of the Fermentation Medium is low, and compared with the Fermentation Medium for producing trichotoxin in prior art, the yield of trichotoxin is significantly improved, provides new train of thought for the cost reduction and benefit increase in the process of large-scale production of trichotoxin.