The invention relates to a pregabalin controlled release preparation, and a preparation method thereof. The pregabalin controlled release preparation comprises following ingredients, by weight, 30 to 75% of pregabalin, 5 to 40% of a filling material, 5 to 30% of a sustained-release material, 1 to 10% of an adhesive, and the balance an auxiliary material. The auxiliary material is one or more selected from magnesium stearate, talc, superfine silica powder, cetanol, octadecanol, liquid paraffin, stearic acid, sodium bicarbonate, magnesium carbonate and calcium carbonate; the sustained-release material is one or a mixture of more selected from ethyl cellulose, carbomer, polycarbophil, alginate, hydroxypropyl methyl cellulose, polyacrylic resin, and carnauba wax. The pregabalin controlled release preparation is capable of prolonging residence time of medicine in stomach, releasing long-lasting release and absorption of medicine, and further increasing bioavailability of medicine.