392results about How to "Prolong the action time" patented technology

The invention relates to the field of traditional Chinese medicine effective component new dosage form pharmaceutical preparations, and discloses an M2 type macrophage membrane coated ROS responsive bionic nano drug delivery system, preparation and application. Mesoporous silica is used as a core to load a traditional Chinese medicine effective component, namely tripterine, and lipid components, namely PEGylated distearoyl phosphatidyl ethanolamine (DSPE-PEG), dioleoyl lecithin (DOPC), cholesterol and the like, are used as raw materials to prepare a ROS-responsive lipid coating, so that ROS-responsive tripterine mesoporous silica is formed. And then realizing bionic fusion with the M2 type macrophage membrane on the outer layer through an ultrasonic coating technology to prepare the M2 type macrophage membrane coated ROS responsive bionic mesoporous silica nano drug delivery system. The invention can realize targeted therapy of rheumatoid arthritis, and has the advantages of biological safety and the like.

The invention discloses a compound enzyme preparation for improving the absorption and utilization rate of a fertilizer and a preparation method thereof, and belongs to the technical field of enzyme preparations. The compound enzyme preparation is prepared from the following components in parts by weight: 100 parts of purified water, 6 to 8 parts of modified cellulase, 10 to 12 parts of immobilized protease, 10 to 12 parts of phosphatase, 10 to 14 parts of urease, 8 to 10 parts of nitrate reductase, 10 to 12 parts of pectinase, 8 to 10 parts of chitinase, 6 to 8 parts of xylanase, 10 to 12 parts of beta-glucosidase, 10 to 12 parts of superoxide dismutase and 4.5 to 6 parts of a microbial agent, the modified cellulase is obtained by chemically modifying cellulase; the immobilized protease is prepared by the following steps: adsorbing activated and coupled modified polylactic acid and a protease solution, crosslinking with glutaraldehyde, filtering, washing and drying. The compound enzyme preparation improves the fertilizer absorption and utilization rate of plants.

The invention relates to the technical field of biological medicines, in particular to a sulfonamide compound for treatment and an enantiomer thereof as well as a preparation method and application thereof, and has the beneficial effects that the provided sulfonamide compound and the enantiomer thereof have the characteristics of strong stability, longer action effect, better drug effect and the like; the compound is a better diuretic and new anti-encephaledema medicine.

A segment of short-sequence polypeptide which can be separated in vitro is obtained through screening, and the short-sequence polypeptide is applied to polypeptide drugs such as analogues or derivatives of GLP-1, so that the stability of the polypeptide drugs can be improved, the action time of the polypeptide drugs can be prolonged, and the biological activity of the polypeptide drugs can be improved.

The invention discloses a nasal gel for treating allergic rhinitis and a preparation method thereof, and relates to the technical field of medicines. The nasal gel for treating allergic rhinitis is prepared from double-sensitive double-network drug-loaded gel microspheres and a temperature-sensitive gel material, the double-sensitive double-network drug-loaded gel microspheres are prepared from sodium alginate, a temperature-sensitive polymer, lactoferrin, a traditional Chinese medicine extracting solution and calcium chloride, the temperature-sensitive gel material is prepared from silk fibroin, carboxymethyl chitosan, K-carrageenan and genipin; the double-sensitive double-network drug-loading gel microspheres are loaded in the temperature-sensitive gel material, and after the temperature-sensitive gel material enters the nasal cavity, the temperature-sensitive gel material is quickly converted into gel to be adhered to nasal cilia, so that the removal of the double-sensitive double-network drug-loading gel microspheres by the motion of the nasal cilia is reduced, and the gel microspheres can better release a double-layer drug-loading system; the acting time of the medicine in the nasal cavity is prolonged, the bioavailability of the medicine is improved, the allergic rhinitis is effectively treated, and uncomfortable symptoms are relieved.

The invention belongs to the technical field of biomedical materials, and particularly relates to a hydrogel wound dressing and a preparation method and application thereof. The hydrogel wound dressing disclosed by the invention can be matched with a sound-sensitive agent by utilizing the temperature-sensitive shrinkage performance of the temperature-sensitive compound monomer, and shows ultrasonic thermal response shrinkage performance, specifically, the hydrogel wound dressing can be rapidly heated and remarkably shrunk under the ultrasonic action to promote wound shrinkage, so that wound healing is accelerated. The obvious potential is embodied in the aspects of promoting the repair of the wound infected by the drug-resistant bacteria and the repair of the wound infected by the drug-resistant bacteria and diabetes mellitus. When the prepared hydrogel wound dressing is used, the contraction degree of the hydrogel wound dressing can be controlled by adjusting the ultrasonic time in the treatment process, and protection and treatment effects on drug-resistant bacteria wounds are achieved in a programmed mode. Meanwhile, the fixing structure of the hydrogel can anchor added drugs such as a sound-sensitive agent and the like, and the action time of the drugs is prolonged.

The invention belongs to the technical field of veterinary preparations, and particularly relates to a tilmicosin premix and a preparation method thereof. The tilmicosin premix is prepared from the following raw materials: tilmicosin, a polylactic acid-glycolic acid copolymer, lecithin, modified hydroxypropyl methyl cellulose, grafted polyvinylpyrrolidone, polyethylene glycol and an antioxidant, a solid dispersion is formed through lecithin and grafted polyvinylpyrrolidone, the solubility and stability of tilmicosin are enhanced, polylactic acid-glycolic acid copolymer nano-microspheres are prepared through a double-emulsion solvent evaporation method, slow release of drugs is achieved, dodecyl modified hydroxypropyl methyl cellulose and polyethylene glycol are combined, and the sustained release effect is achieved. The solubility and the slow release characteristic are further enhanced. The activity of the granular premix is effectively preserved, and the granular premix is convenient to use and transport.

The invention belongs to the field of preparation of sedation maintaining agents, and particularly relates to a sedation maintaining agent administrated through oral mucosa and a preparation method of the sedation maintaining agent. Bamboo leaf polysaccharide and pigskin collagen peptide are heated and mixed with chlorogenic acid and butyl acetate under the catalytic action of lanthanum nitrate, and the obtained moisturizing adhesive has biocompatibility, can be stably adhered to oral mucosa and can promote salivary secretion of children; nanoparticles obtained through freeze spray drying are uniformly dispersed in a copolymer solution containing sodium salicylate and polyacrylate, and the obtained nervous system regulator can balance excitability of sympathetic nerves and parasympathetic nerves of children; the emotion relieving composition contains modified felwort powder obtained through esterification reaction, the modified felwort powder is mixed with a moisturizing adhesive and a nervous system regulator, and the prepared sedation maintaining medicament administrated through the oral mucosa protects oral health of children in the oral operation anesthesia process, is free of irritation, improves anxiety emotion and does not affect postoperative awakening.

The invention provides a composite water dispersible granule containing emamectin benzoate and a preparation process thereof, and belongs to the technical field of pesticide preparation. The preparation process comprises the following steps: preparing a modified carrier material; preparing a light controlled release carrier material; and preparing the composite water dispersible granule. The light controlled-release carrier material is prepared by taking bentonite as a raw material, and when the carrier material is used for loading pesticide raw material components, pesticide raw material molecules can be slowly released from pores and surfaces of the bentonite, so that the release speed of the pesticide is effectively controlled, the action time of the pesticide is prolonged, and the pesticide effect is improved. In addition, methyl cinnamate is grafted on the surface of a modified carrier material to prepare a light controlled-release carrier material, and after the light controlled-release carrier material is loaded with an insecticide raw medicine, the release rate of the insecticide raw medicine is reduced under the irradiation of strong light, so that the situation that the pesticide effect is reduced due to light degradation after the insecticide liquid is released can be avoided.

The invention relates to mussel mucin-hyaluronic acid nanogel and a preparation method and application thereof and a pharmaceutical composition, and belongs to the field of biomedical materials, the structural formula of the mussel mucin-hyaluronic acid nanogel is # imgabs0 #, Mussel mucin is a mussel mucin molecule, and n is the number of repetitive units. The mussel mucin-hyaluronic acid nanogel can be swelled in a water-based medium to form a three-dimensional space net-shaped structure, pharmaceutical active molecules are better entrapped, lysine and dopa groups in the structure can be tightly combined with the surface or mucous membrane of an organism through electrostatic interaction, hydrogen-bond interaction and oxidative crosslinking, so that the bioavailability of the mussel mucin-hyaluronic acid nanogel is improved, and the bioavailability of the mussel mucin-hyaluronic acid nanogel is improved. The carrier has good biological adhesion, can prolong the residence time of the carrier on an organism or mucous membrane surface, and promotes drug absorption. The mussel mucin-hyaluronic acid nanogel can also be used as a drug storage cavern, so that the slow release effect of drugs is improved, the action time of the drugs is prolonged, and the administration frequency is reduced.

The invention belongs to the field of medicines, and discloses a crystal of difloxacin and a salt-based compound thereof, the grain size of the crystal is 200nm-10mu m, and the crystal is of a sheet structure. The crystal provided by the invention has the particle size of 200nm-10mu m, is of a sheet structure, can stably exist in water in a suspension form, has the advantages of long acting time and small irritation, does not block a needle head, and can be prepared into preparations with various concentrations. Meanwhile, the invention also discloses a preparation method of the crystal.

The invention belongs to the technical field of seedling raising substrates, and particularly relates to a seedling raising substrate based on straw and cow dung and a preparation method thereof.The seedling raising substrate based on straw and cow dung is prepared from, by weight, 20-40 parts of dry cow dung, 20-40 parts of straw segments, 10-20 parts of ferroferric oxide composite water-absorbent resin, 6-8 parts of EM bacteria and 40-60 parts of field soil. The preparation method comprises the following steps: grafting a silane coupling agent on the surface of ferroferric oxide, then carrying out polymerization reaction on the surface of the ferroferric oxide grafted with the silane coupling agent and acrylic acid to generate ferroferric oxide-sodium polyacrylate particles, and the ferroferric oxide-sodium polyacrylate particles are magnetic particles. And the surfaces of the ferroferric oxide-sodium polyacrylate particles have abundant carboxyl (-COOH) and sodium carboxylate (-COONa) functional groups. The functional groups can form hydrogen bonds or ionic bonds with water molecules, so that the hydrophilicity and water absorption of the surfaces of the particles are improved.

The invention relates to the field of plant growth regulators, in particular to an ultramicro-granulated energy-gathered humic acid composite preparation which is prepared from the following raw materials in parts by weight: 50-80 parts of ultramicro-granulated energy-gathered humic acid, 10-30 parts of nanoscale metal oxide, 5-20 parts of a microbial agent, 1-10 parts of a plant growth regulator and 5-15 parts of a slow release agent. According to the invention, ultrafine particle shaped humic acid, nano-scale metal oxide, a microbial agent, a plant growth regulator and a slow-release agent are organically combined. The effect of the soil conditioner is far better than that of a single component or a traditional soil conditioner.

The invention discloses a compound plant stress-resistant agent as well as a preparation method and application thereof. The compound plant stress-resistant agent comprises a compound of glycine betaine and polyglutamic acid, wherein the mass ratio of the glycine betaine to the polyglutamic acid is 1: (0.1-2). The preparation method of the composite plant stress-resistant agent comprises the following steps: mixing polyglutamic acid or a solution thereof with glycine betaine in ethanol to obtain a mixed solution, adjusting the pH value of the mixed solution to 3.0-6.0, carrying out an ultrasonic reaction to obtain a reaction solution, adding absolute ethyl alcohol into the reaction solution, stirring, filtering, and drying the precipitate to obtain the composite plant stress-resistant agent. The compound plant stress-resistant agent can be applied to crops in a foliage spraying or root irrigation mode, the growth conditions of grain crops such as corn, peanuts, celery and grapes and / or economic crops under adversity stress such as drought, low temperature and high salt are remarkably relieved, and the crop yield is increased.

The invention provides an oral cavity soluble film solution based on a nano-carrier and a preparation method of an oral cavity soluble film. According to the method, a nano-carrier technology, microcapsule multilayer coating, a low-temperature electrochemical polymerization method and an ultrasonic dispersion technology are utilized, and uniform distribution and multi-stage slow release of a medicine in an oral instant film are achieved. According to the invention, active pharmaceutical ingredients are firstly wrapped by a nano-carrier, and then a multi-layer composite coating structure is formed by a microcapsule technology, so that drug release effects at different stages are realized. And then, uniformly mixing the microcapsule nano-drug particles with a film-forming substrate, depositing layer by layer to form a film through a low-temperature electrochemical polymerization method, and carrying out low-temperature drying treatment. The soluble film disclosed by the invention has good biocompatibility and mechanical strength, and can be gradually dissolved in an oral cavity, and the medicine is released according to a set stage, so that a long-acting oral care or treatment effect is realized. The method avoids the use of high temperature and organic solvents, is environment-friendly and safe, and is suitable for delivery systems of various oral drugs.

The invention belongs to the technical field of oral preparations, and particularly relates to a collagen composition for brightening skin and a preparation method thereof. The collagen composition is prepared from the following raw materials in parts by weight: 40 to 60 parts of fish collagen peptide, 2 to 5 parts of arbutin extract, 0.1 to 0.5 part of black pepper extract, 3 to 6 parts of glutathione, 1 to 3 parts of ellagic acid, 1 to 2 parts of shea butter, 3 to 5 parts of antioxidant, 1 to 2 parts of squalane, 1 to 2 parts of ceramide, 0.5 to 1 part of sodium bicarbonate, 5 to 10 parts of beta-cyclodextrin, 1 to 3 parts of lecithin and 0.5 to 1 part of silicon dioxide. According to the invention, the polyethylene glycol grafted aminated nano cellulose magnetic carrier is used for immobilizing the enzyme, so that the thermal stability and denaturation resistance of the enzyme are improved, the crosslinking is optimized, the enzyme activity is retained, the recovery process is simplified, the cost is reduced, the yield and quality of the collagen peptide are improved, active ingredients are protected through nanocrystallization and embedding technologies, and the absorption efficiency and the product stability are enhanced.

The invention belongs to the field of medicines, and particularly relates to a difloxacin microcrystal suspension injection which comprises water and a difloxacin crystal existing in the water in a suspension state. The particle size of the difloxacin crystal is 200 nm to 10 [mu] m, and the difloxacin crystal is of a sheet structure. The particle size of the difloxacin crystal in the difloxacin microcrystalline suspension injection provided by the invention is 200nm-10mu m, the difloxacin crystal is of a sheet structure, the crystal can stably exist in a liquid carrier in a suspension form, and after being prepared into the injection, the difloxacin microcrystalline suspension injection has the advantages of long acting time, small irritation and no blockage of a needle tube, and can be prepared into preparations with various concentrations. Meanwhile, the invention also provides a preparation method of the suspension injection.

The present invention proposes a Chinese medicine composition for treating allergic rhinitis, and a preparation method and application thereof, which belong to the field of pharmaceutical technology. Ag-graphene oxide is adsorbed on in vitro proliferated γδT cells, a Chinese medicine fermentation product obtained by fermentation and extraction of Xanthium sibiricum, Astragalus, Poria, Magnolia officinalis, and Mentha is prepared, berberine and quercetin are prepared into eutectic powder, the three are mixed and added into water, probiotics, carboxymethyl chitosan, poloxamer 407 and poloxamer 188 are added, and mixed evenly to prepare a Chinese medicine composition for treating allergic rhinitis, which has a good effect of improving allergic rhinitis, adopts a method of combining traditional Chinese and Western medicine, reduces inflammatory response, enhances the immune function of patients, improves the clinical symptoms of patients with allergic rhinitis, reduces the long-term recurrence rate, reduces the use of drugs, improves the quality of life, and reduces the risk of developing asthma, and has broad application prospects.

The invention discloses a microcapsule as well as a preparation method and application thereof. The microcapsule comprises a capsule core and a capsule wall, the capsule core is wrapped in the capsule wall, the capsule core contains an active component, the elastic modulus of the microcapsule and the thickness of the capsule wall meet the following formula: Y = 0.42 X < 2 >-0.92 X + T, Y is the elastic modulus of the microcapsule, and the unit is GPa; x is the thickness of the capsule wall, and the unit is [mu] m; t is 1 + / -0.1; the elastic modulus of the microcapsule is obtained by testing the mechanical property of the microcapsule by adopting a nanoindentor, and the thickness of the capsule wall is obtained by testing the frozen section of the microcapsule by adopting a scanning electron microscope. The microcapsule provided by the invention is suitable for pavement asphalt, and can effectively improve the self-repairing efficiency of a pavement asphalt material; in addition, in the asphalt construction process, the emission of asphalt smoke can be effectively reduced, and the pollution to the environment is reduced.

The invention discloses a podophyllotoxin triazole ether derivative as well as a preparation method and application thereof, belongs to the technical field of chemical pharmacy, and particularly relates to a podophyllotoxin triazole derivative and application of the podophyllotoxin triazole ether derivative in preparation of antitumor drugs. A series of novel 1, 2, 3-triazole podophyllotoxin derivatives are designed and synthesized by combining a triazole structure with a podophyllotoxin matrix through click chemistry reaction, the dynamic characteristics of podophyllotoxin are optimized by introducing the triazole structure, and the anti-cancer effect and druggability of podophyllotoxin are improved. Molecular docking shows that the series of compounds have relatively strong binding energy to AKT1 and tubulin and can inhibit tubulin / AKT1 in a targeted manner, and in-vitro anti-tumor activity research shows that the molecules have very strong inhibitory activity to proliferation of human colon cancer cell strains, and a new strategy can be provided for structural derivatization of podophyllotoxin. # imgabs0 #

The invention belongs to the technical field of bacteriostatic agents, and particularly relates to lemongrass essential oil microcapsules, a preparation method thereof, a bacteriostatic agent and application. The preparation method comprises the following steps: by taking lemongrass essential oil as a core material and Arabic gum and beta-cyclodextrin as wall materials, mixing the lemongrass essential oil, the Arabic gum and the beta-cyclodextrin, and preparing the lemongrass essential oil micro-capsule by adopting a spray drying method; the mass ratio of the Arabic gum to the beta-cyclodextrin is (0.5-2): 1, and the mass ratio of the total amount of the Arabic gum and the beta-cyclodextrin to the lemongrass essential oil is (4-6): 1. And then mixing the lemongrass essential oil microcapsules with starch and ethanol, granulating and drying to obtain the antibacterial patch. The lemongrass essential oil microcapsule disclosed by the invention is stable in quality, the action time of the lemongrass essential oil is prolonged, the purpose of long-acting bacteriostasis is achieved, and the technical defect of short action time of a lemongrass essential oil antibacterial agent in the prior art is overcome.

The invention discloses an advanced reactor core system and a water replenishing method, and belongs to the technical field of reactor equipment, the advanced reactor core system comprises a reactor core pressure system and at least two safety injection systems, and each safety injection system comprises a water replenishing mechanism and a water injection mechanism. The effect of automatically adjusting the flow is achieved through the multiple sets of water passing holes formed in the water outlet pipe in the water supplementing container from top to bottom, the flow of cooling liquid conveyed to the pressure container through the water supplementing container is better matched with the requirement, the water supplementing continuity is improved, the acting time of the water supplementing container is greatly prolonged, and therefore the system pressure is reduced, and the system safety is improved. It is ensured that the low-pressure water injection mechanism can be put into operation before the water supplementing container lacks water, namely, the input pressure of the low-pressure water injection pump is reduced, the structure is simple, the action time of passive injection is prolonged, dependence on an emergency power supply at the initial stage of an accident is reduced, and meanwhile the requirements for pump flow and a pressure head are reduced; and the reliability and economical efficiency of the safety injection system are obviously improved.

The invention discloses a food packaging bag and a preparation method thereof, and belongs to the technical field of packaging bags, the food packaging bag is prepared from the following raw materials in parts by weight: 28-38 parts of polylactic acid, 2-12 parts of poly-2, 5-butylene furandicarboxylate, 2-5 parts of POSS-based compatibilizing component and 0.6-1.2 parts of modified zero-valent nano-iron, the preparation method of the packaging bag comprises the following steps: mixing the polylactic acid, the poly-2, 5-butylene furandicarboxylate, the POSS-based compatibilizing component and the modified zero-valent nano-iron, and uniformly stirring; the preparation method comprises the following steps: respectively drying 1, 3, 5-butylene furandicarboxylate in an oven at 80 DEG C for 12 hours, then adding the dried 1, 3, 5-butylene furandicarboxylate, the POSS-based compatibilizing component and the modified zero-valent nano-iron into a mixer, stirring for 30 minutes, transferring into a screw extruder, carrying out melt extrusion to obtain composite material particles, preparing the composite material particles into a food packaging film by adopting a tape casting method, and then cutting to obtain the food packaging bag. The packaging bag not only has good biodegradability, but also has good mechanical properties and an excellent fresh-keeping effect.

The invention provides a preparation method of a two-dimensional nanobelt. The two-dimensional manganese risedronate nanobelt (RMn-NBs) is prepared from Mn < 2 + > and risedronate sodium by using a coordination self-assembly technology. The raw materials are cheap and easy to obtain, and the preparation process is simple, easy to operate and good in controllability. The two-dimensional risedronate manganese nanobelt can inhibit a hypoxia-inducible factor / vascular endothelial growth factor (HIF-1alpha / VEGF) through risedronate sodium so as to enhance the radiotherapy effect; meanwhile, Fenton-like reaction of Mn < 2 + > is utilized to amplify oxidative stress mediated by radiotherapy, a GMP-AMP synthetase stimulating factor (cGAS-STING) pathway of an interferon gene ring is synchronously activated, secretion of I-type interferon is promoted, ICD (immunogen cell death) is effectively induced, and the immunogen cell death rate is increased. And the effects of CD8 + T cell dependent systemic anti-tumor immunity and checkpoint blocking immunotherapy on primary and metastatic tumors are greatly enhanced. The RMn-NBs is used as a novel nanoscale in-situ radiotherapy vaccine, and has good biocompatibility and treatment effect.

The invention relates to the field of agricultural pest control, and discloses a composite pest control agent based on a plant extract as a core. Comprising 15%-25% of honeysuckle extract, 10%-20% of podophyllum hexandrum extract, 15%-25% of camellia peel extract, 10%-20% of wikstroemia indica extract, 10%-20% of senecio scandens extract, 10%-20% of lycoris radiate extract, 1%-3% of a synergist, 5%-10% of an emulsifier and a solvent. According to the invention, a plurality of plant extracts are fused, and effective prevention and control of a plurality of fungi, bacterial diseases and pests are realized through accurate optimization of the ratio. Compared with a current technology which only adopts a single plant extract, the method has the advantages that the comprehensive prevention and treatment efficiency is remarkably improved, the problems of limited prevention and treatment range and poor multi-pest control effect are successfully solved, and the blank in the research and application field of the compound plant extract prevention and treatment agent is filled.

The invention belongs to the technical field of biological materials, and particularly relates to a multifunctional beauty microneedle for improving skin photoaging and a preparation method and application thereof. According to the invention, water-soluble hyaluronic acid and chitosan / beta-sodium glycerophosphate temperature-sensitive hydrogel are used as a polymer of a microneedle substrate layer, and the polymer comprises exosome of human adipose-derived mesenchymal stem cells and epigallocatechin gallate. When the microneedle is inserted into the skin, hyaluronic acid is quickly dissolved after contacting with tissue fluid, the needle tip is implanted into the skin, and the CS / beta-GP temperature-sensitive hydrogel is in a solid-gel-like state and can slowly release two cosmetic active ingredients in a long-acting manner under the influence of environment temperature and humidity; the facial mask has the effects of promoting tissue regeneration, reducing hyperpigmentation, replenishing water, preserving moisture, resisting oxidation, delaying skin aging and the like, so as to achieve the medical beauty effects of reducing wrinkles, whitening, preserving moisture, rejuvenating the face and the like. The microneedle provided by the invention can be further prepared into a patch, and is beneficial to treatment of wrinkles and stains at specific parts.

The invention provides an application of polylactic acid and a copolymer thereof in preparation of a medicine for promoting nerve growth and repairing, the molecular weight of the polylactic acid and the copolymer thereof is 400-300k Da, and the medicine has the following effects: 1) promoting growth of nerve cells and nerve tissues; 2) promoting the repair of nerve cells and nerve tissues; 3) treating or preventing peripheral nerve injury, spinal cord injury, peripheral neuropathy and neuritis; preferably, the molecular weight is in the range of 5000 to 100 k Da. The invention discovers that polylactic acid and the copolymer thereof have a protection effect on nerves for the first time, and can promote growth of the nerves and repair of nerve injury.

The invention provides a preparation method of a biological functional agent containing bioactive components, which comprises the following steps: dispersing the bioactive components in water; adding the zeolite-loaded titanium dioxide composite material, absolute ethyl alcohol, isopropyl triisostearoyl titanate and polyvinylpyrrolidone into the mixed solution, stirring at the temperature of 65-75 DEG C to obtain a mixed solution containing bioactive components, stirring for 80-100 minutes, and centrifugally drying to obtain the composite material. According to the preparation method of the biological functional agent containing the bioactive components, the loading capacity of the bioactive components on the carrier is improved, the stability of the bioactive components is improved, and the slow release effect is enhanced, so that the preparation efficiency and performance of the biological functional agent are improved; wide prospects are provided for application in the fields of medicines, cosmetics, environmental protection and the like.

The invention provides a modified oxygen-releasing nano peroxide for degrading organic pollutants, a composite oxygen-releasing material, a preparation method and an application. The modified oxygen-releasing nano peroxide comprises an oxygen-releasing nano peroxide, a pH regulator, a polyvinyl alcohol-poly (N-isopropylacrylamide) membrane layer and a cross-linked chitosan membrane layer, the polyvinyl alcohol-poly (N-isopropylacrylamide) membrane layer wraps the oxygen-releasing nano peroxide and the pH regulator, and the cross-linked chitosan membrane layer wraps the oxygen-releasing nano peroxide and the pH regulator. The polyvinyl alcohol-poly (N-isopropylacrylamide) film layer is coated with the cross-linked chitosan film layer. The modified oxygen-releasing nano peroxide is high in purity and good in dispersity, the content of dissolved oxygen in a water body can be kept stable for a long time, and the influence on the pH value of the environment is small.

The invention discloses a vehicle-mounted gear shifting control center control injection mold, which belongs to the field of injection molding of automotive upholstery and comprises a positioning plate, a connecting column fixedly connected to one side of a top plate, a movable mold fixedly connected to the other end of the connecting column, a fixed mold connected to the other side of the movable mold and an ejection unit connected between the positioning plate and the movable mold. The ejection unit comprises a plurality of guide columns II which are fixedly connected between the positioning plate and the movable mold; according to the scheme, the rotating circular scraper can be in all-dimensional contact with the outer surface of the ejector pin, dirt on the surface is cleaned more uniformly, automatic cleaning of the dirt on the outer surface of the ejector pin is achieved, the situation that the dirt is carried into a gap when the ejector pin enters a movable mold is avoided, and the action time of lubricating oil is prolonged; the lubricating part sprays lubricating oil to the cleaned ejector pin to achieve automatic lubrication, the ejector pin can be cleaned and lubricated in the mold injection molding process, the production efficiency of the mold is improved, and manpower resources are saved.