76 results about "Bacteriostatic agent" patented technology

The application discloses a pH-responsive degradable composite bacteriostatic film derived from waste bone powder extract and a preparation method thereof. The main components of the film are collagen and hydroxyapatite extracted from waste bone powder, citric acid monohydrate-betaine and lactic acid-betaine eutectic solvent, and in addition, purple corn anthocyanin is used as a pH response agent, and citric acid monohydrate-betaine eutectic solvent is used as a crosslinking agent and a bacteriostatic agent. In the preparation process, collagen and hydroxyapatite are mixed with an aqueous solution of eutectic solvent and heated, and after the system is reduced to room temperature, the anthocyanin aqueous solution is added, mixed, and ultrasonic defoaming is performed, then the film forming liquid is poured into a clean mold, vacuum dried, and cooled to remove the film. The pH-responsive degradable composite film prepared based on the above method has good properties, not only has the characteristics that the overall color changes with the microenvironment pH, but also has good mechanical strength, bacteriostasis and degradability, and has wide application potential in many fields such as food preservation.

This invention relates to the field of disinfection device technology, specifically to an air sterilizer that facilitates the addition of biological antibacterial agents. The device includes a base, a filter cartridge detachably mounted on the upper end of the base, a top cover plate detachably mounted on the upper end of the filter cartridge, an exhaust motor fixedly mounted on the inner end of the top cover plate, exhaust blades rotatably mounted on the inner end of the top cover plate, a support cylinder fixedly mounted on the inner end of the base, and multiple output cylinders fixedly mounted on the surface of the support cylinder. A suction device for extracting the biological antibacterial agent is provided between the support cylinder and the storage cylinder. This device uses the exhaust motor to drive the exhaust blades to form a stable airflow, and utilizes the linkage structure of the central tube, crown gear, and passive cylinder to actively bring the refined biological antibacterial agent into the air circulation channel. The biological antibacterial agent is forced to be transported into the filter cartridge under the action of the airflow and discharged with the airflow, thereby significantly improving the diffusion speed and coverage of the biological antibacterial agent in the air.

The present invention relates to the field of biological fermentation application technology, and in particular, to use of a milk peptide fermentation product in regulating skin microecological balance. The milk peptide fermentation product selectively regulates the growth of Staphylococcus epidermidis and inhibits the growth of Staphylococcus aureus and Escherichia coli. It was discovered for the first time that the milk peptide fermentation product has a selective bacteriostatic effect on skin microorganisms. The experimental results show that the milk peptide fermentation product has an inhibitory effect on Escherichia coli and Staphylococcus aureus, but has no effect on the normal growth of Staphylococcus epidermidis. This characteristic is obviously different from common broad-spectrum chemical bacteriostatic agents, and the use of the milk peptide fermentation product is more conducive to maintaining the balance of skin microbiota.

The present application relates to the technical field of pesticides, and discloses a chromene aryl hydrazide derivative, a preparation method and application thereof, a structural general formula of the chromene aryl hyydrazide derivative is as formula (I); the preparation method is as follows: taking p-hydroxybenzaldehyde as raw material, and obtaining the chromene aryl hydrazide compound through substitution reaction, cyclization reaction, oxidation reaction, acylation reaction and hydrazinolysis reaction. The chromene aryl hydrazide compound is used for preparing an agricultural bacteriostatic agent. The present application combines aryl hydrazine and chromene skeleton by using the pharmacophore splicing principle in medicinal chemistry, and designs and synthesizes a series of chromene aryl hydrazide compounds. The bacteriostatic activity test result shows that the compounds have excellent bacteriostatic activity, and can be used as active ingredients for preparing a plant pathogenic fungus fungicide.

The application discloses an anti-inflammatory soothing repair polypeptide composition containing tripeptide-125 and a preparation method and application thereof, and relates to the technical field of cosmetic polypeptides. The efficacy components of the composition comprise palmitoyl tripeptide-8, acetyl dipeptide-1 cetylester and tripeptide-125. The anti-inflammatory soothing repair polypeptide composition is prepared by using the efficacy components, a solvent, a solubilizer and a bacteriostatic agent, and has good anti-inflammatory, soothing and skin barrier repair performance.

This application discloses a method for preparing a polyepoxysuccinic acid-modified sulfur quantum dot scale inhibitor and antibacterial agent, belonging to the field of water treatment nanomaterials. The method includes: preparing nitrogen-doped sulfur quantum dots; reacting polyepoxysuccinic acid or its derivatives with nitrogen-doped sulfur quantum dots to obtain a composite product; purifying the composite product; and concentrating, drying, and grinding the purified composite product to obtain the scale inhibitor and antibacterial agent. This application modifies the surface functional groups of sulfur quantum dots with polyepoxysuccinic acid or its derivatives, endowing the product with abundant active functional groups. This allows the product to inhibit the formation of calcium carbonate scale through chelation solubilization, crystal form regulation, and adsorption dispersion mechanisms, while retaining the intrinsic antibacterial properties of sulfur quantum dots, effectively inhibiting bacterial growth in water while inhibiting scale formation. This preparation method is environmentally friendly, with mild reaction conditions, and the resulting scale inhibitor and antibacterial agent has good reservoir compatibility, making it suitable for high-salinity and high-temperature environments in oil fields.

The application discloses application of eugenol in preparation of a bacteriostatic agent for enhancing symbiotic nitrogen fixation efficiency of legume-rhizobium, and relates to the field of agricultural microorganisms. ‑1 The application is safe and non-inhibiting to seed germination of Medicago polymorpha and target rhizobium LL2 in a concentration range of 500-1000 muL / L ‑1 of eugenol, can significantly reshape rhizosphere microbial community structure by selectively inhibiting competitive microorganisms such as bacillus and streptomyces in soil, and is environment-friendly and free of antibiotic residue risk, thereby providing a green and efficient new approach for improving symbiotic nitrogen fixation efficiency of legume-rhizobium.

This invention relates to the field of vegetable fermentation processing technology, specifically a fermentation method for pickling selenium-enriched arrow-shaped white cabbage with zero nitrite content. The method includes the following steps: selecting selenium-enriched arrow-shaped white cabbage with a selenium content of 0.05-0.6 mg / kg, washing, removing impurities, and cutting it, then drying it with sterile air until there is no free water on the surface; layering the treated selenium-enriched arrow-shaped white cabbage into a sealed fermentation tank, and activating an adjustable pressing device to compress the material until it is completely submerged below the fermentation liquid surface. This invention utilizes directional lactic acid bacteria-dominated fermentation and a strong anaerobic environment to completely inhibit nitrate-reducing bacteria, resulting in nitrite content far below national standards. The synergistic effect of the selenium-enriched protective liquid and the anaerobic environment significantly enhances the nutritional value of the product. Simultaneously, it employs low-salt fermentation, without adding preservatives or using chemical antibacterial agents, and the adjustable pressing device prevents the raw materials from floating and deteriorating, reducing losses.

An analgesic, antipruritic, tissue-regenerating, wound-healing, and antibacterial ointment and its preparation method are disclosed. This invention relates to the field of traditional medicine and skin antibacterial preparations. It comprises the following components by weight: 400-600 parts sesame oil, 30-80 parts beeswax, 25-100 parts a plant-based medicinal composition, 5-25 parts an animal-based medicinal composition, 1-5 parts a mineral-based medicinal composition, and 0.1-0.3 parts an antibacterial agent. The plant-based medicinal composition includes elm branches, willow branches, purple gromwell root, and jujube branches; the animal-based medicinal composition includes dragon's blood and earthworm; the mineral-based medicinal composition is red silver pearl powder; and the antibacterial agent is chlorhexidine acetate. Using pure natural Chinese medicinal herbs as core raw materials, with a reasonable formulation and stable preparation process, it has rapid analgesic, antipruritic, hemostatic, antibacterial, tissue-regenerating, and wound-healing effects. It has significant effects on acute trauma, burns, and chronic, difficult-to-heal wounds, is safe and non-irritating, and has controllable quality.

The application discloses a pet nest pad carbon fiber bacteriostatic and odor-resistant composite fabric, and belongs to the technical field of functional textile fabrics for pet homes. In view of the breeding pain points that bacteria and fungi are easily bred in the nest pad where pets lie for a long time, the odor of pet sweat and excrement residues is heavy, ordinary nest pad fabrics are not bacteriostatic and odor-resistant, odor residues and mildew pilling occur after washing, and pet skin is easily infected and allergic, modified carbon fiber and polyester skin-friendly fibers are blended and woven, a surface stain-resistant and breathable coating is compounded, and the blending mass ratio of carbon fiber is strictly limited to 10%-15%. The application relies on the physical bacteriostatic and adsorptive properties of carbon fiber, long-acting adsorption of pet odor, humidity and excrement residue odor, inhibition of the breeding and reproduction of bacteria and fungi, fabric wear resistance and pilling resistance, water washing resistance, no obvious attenuation of bacteriostatic and odor-resistant performance after 50 times of washing, no chemical bacteriostatic agent residues, no stimulation and no toxicity, adaptation to long-term lying of various pets such as cats and dogs, protection of pet skin health, and no pet odor pollution in indoor homes.

The present application belongs to the technical field of eye drops, and particularly relates to a pet in-situ gel sustained-release eye drop. The present application provides a pet in-situ gel sustained-release eye drop aiming at the problem that the in-situ gel sustained-release eye drop with significant sustained-release effect and suitable for physiological characteristics of pet eyes has not been developed in the prior art, and the pet in-situ gel sustained-release eye drop comprises main drugs, response materials, pH regulators, osmotic pressure regulators, bacteriostatic agents, thickening agents and water for injection in a mass ratio of 0.05-5.0:0.1-2.0:0.1-5.0:0.5-5.0:0.01-0.5:0.005-1.0:94.0-97.0. The present application provides an in-situ gel sustained-release eye drop with significant sustained-release effect and suitable for physiological characteristics of pet eyes, which is suitable for dogs and cats of all ages, including young pets, old pets and pets with sensitive eyes, has no obvious drug contraindications, has a wide application range and high practicability.

The application provides a kind of taro seedling transplanting planting method using wheat stubble, first, preparation substrate and seedling container, the substrate contains sandy soil, granular slow-release fertilizer, chelated slow-release fertilizer, bacteriostatic agent, rooting agent, the seedling container includes seedling bag and seedling box;Select the seed ball or lateral bud of taro for seedling, and transplant to wheat stubble and plant;After transplanting, regular fertilization and watering, until the taro grows to maturity.The application proposes two seedling transplanting methods suitable for baimiao taro, wherein the seed ball seedling method can shorten the field growth period of taro;Another lateral bud seedling transplanting method not only shortens the field growth period of taro, but also reduces the seedling cost and increases the propagation coefficient.The application shortens the growth cycle by using seedling transplanting, and makes up for the influence on the later yield.Summer high temperature and high humidity and diseases can also be inspected and treated by seedling transplanting in seedling stage, greatly reducing the proportion of seedlings with diseases, further reducing the incidence of field diseases.

The invention relates to a jam inner core used in cheese food and a preparation method thereof. The jam inner core comprises the following components in parts by weight: 10-40 parts of water, 5-20 parts of cream cheese, 10-30 parts of cream, 40-55 parts of jam, 0.5-2 parts of a stabilizer, 0.5-1 part of a thickener and 0.01-0.1 part of a bacteriostatic agent. According to the scheme provided by the invention, the jam inner core has good flowability under the condition that a large amount of jam is added into the jam inner core, and the jam inner core can keep a relatively low pH value under the condition that the jam inner core does not contain an acidity regulator, so that the shelf life can be prolonged.

This invention discloses a plant extract compound antibacterial agent and its application in feminine hygiene products. The raw materials of this plant extract compound antibacterial agent, by weight percentage, include 0.5%~5% antibacterial agent and 0.5%~30% synergistic agent; wherein the antibacterial agent is selected from Magnolia officinalis extract, and the synergistic agent is selected from at least one of Cypress twig extract and Podocarpus macrophyllus extract. This plant extract compound antibacterial agent, by combining the above-mentioned antibacterial agent and synergistic agent, can further broaden the antibacterial spectrum, compensate for the insufficient inhibitory effect of single plant extracts on specific strains, enhance the stability of active ingredients, reduce the risk of activity degradation due to pH and temperature changes during product storage and use, and distinguish itself from chemically synthesized and inorganic antibacterial agents. Its mechanism of action is gentle, inhibiting pathogenic bacteria and effectively maintaining the microecological balance of the feminine hygiene area, avoiding problems such as mucosal dryness and sensitivity caused by long-term use.

This invention relates to an antibacterial agent derived from the peel of *Guiqi* mango and its preparation method, belonging to the field of natural product nanoparticle technology. The method aims to solve the technical problem of how to simultaneously achieve efficient co-extraction of water-soluble and lipid-soluble antibacterial components in a continuous process, and to immediately stabilize easily oxidized components, as well as to construct a high-encapsulation-rate nanoparticle antibacterial agent. The key technical points are: after mixing dried mango peel powder, β-cyclodextrin, and deionized water, a high-voltage pulsed electric field is used to simultaneously achieve cell wall disruption extraction and in-situ molecular inclusion of active ingredients; subsequently, the obtained inclusion extract is mixed with chitosan hydrochloride solution, and then ion cross-linked by adding sodium tripolyphosphate aqueous solution to construct composite nanoparticles; finally, after ethanol aging, centrifugation purification, and redispersing in buffer solution, the final product in nanoparticle form is obtained. The antibacterial agent prepared by this method can be used in the fields of preservation and antibacterial activity.

This invention relates to a compound antibacterial agent and its application in open plant tissue culture. The active ingredients of the compound antibacterial agent include rifampin, kasugamycin, ticarcillin sodium clavulanic acid, and tetrachloroisophthalonitrile. The compound antibacterial agent can synergistically inhibit Agrobacterium rhizogenes or Rhodotorula glutinis, contaminating bacteria that are easily generated during plant tissue culture.

This invention discloses an oral suspension of an anti-tuberculosis drug and its preparation method. The oral suspension contains an anti-tuberculosis drug, a suspending agent, a surfactant, an antibacterial agent, an antioxidant, a flavoring agent, and a pH adjuster. It has technical advantages such as stable physical and chemical properties, uniform content, and easy long-term storage.

The application relates to the technical field of medical materials, in particular to an antioxidant and bacteriostatic chitosan hydrogel and a preparation method thereof. The method is characterized in that lipoic acid is first grafted on a chitosan molecular chain to prepare modified chitosan; then the modified chitosan is mixed with a functional additive, a photo irradiation is performed to initiate ring-opening crosslinking of a lipoic acid disulfide five-membered ring, meanwhile, a mercapto-dithiol exchange reaction occurs between mercapto groups on the surface of the functional additive and a disulfide bond, and a three-dimensional network hydrogel is rapidly formed; the functional additive is prepared through ultraviolet light reaction of mercapto titanium oxide microspheres, a synergistic bacteriostatic agent and a modifier, and a three-dimensional bacteriostatic network layer is formed on the surface of the titanium oxide microspheres; the chitosan hydrogel prepared by the method has excellent antibacterial performance and good antioxidant performance, is suitable for the biomedical field such as wound dressings, tissue engineering scaffolds and drug sustained-release carriers, and has a wide application prospect.

This invention discloses a dyeing process for antibacterial polyester fabric, belonging to the field of textile dyeing and finishing technology. The process first pre-shapes the polyester fabric using a hot air setting machine, then prepares a dyeing working solution containing disperse dyes, dispersing and leveling agents, and reactive antibacterial finishing agents. The fabric is then placed in a high-temperature, high-pressure dyeing machine for simultaneous dyeing and antibacterial treatment. By controlling the pH value of the dye solution, the heating rate, and the heat preservation parameters, the dye and antibacterial components are simultaneously dyed and fixed. After dyeing, the fabric undergoes sequential washing, reduction cleaning, neutralization, and cationic color fixing treatments. Finally, it is dried in sections and stretched for setting, resulting in the antibacterial polyester fabric. This invention integrates the dyeing process with antibacterial finishing, improving the compatibility of dyes and antibacterial agents, enhancing the fabric's antibacterial durability and color fastness, and is compatible with conventional textile dyeing and finishing equipment. It allows for wastewater recycling, combining high production efficiency and environmental friendliness, and is suitable for industrial-scale mass production.

This invention belongs to the technical fields of biomedicine and daily chemical care industries. It discloses the preparation and application of an antibacterial extract containing Gleditsia sinensis thorns and a formulated combination. Gleditsia sinensis thorns are extracted with 60%–75% ethanol via ultrasonic extraction followed by ethyl acetate extraction, and the extract is purified by column chromatography to obtain a Gleditsia sinensis thorn extract. Eucalyptus leaves and camphor leaves are extracted with supercritical CO2 and purified to obtain essential oils. Sophora flavescens, Gentiana scabra, Lygodium japonicum root, Houttuynia cordata, and Cnidium monnieri are extracted with 70%–85% ethanol via ultrasonic extraction, and the crude extracts are purified using macroporous adsorption resin to obtain extracts. By utilizing the natural antibacterial components of Gleditsia sinensis thorns and its formulated combination, the formulated antibacterial agent not only exhibits high efficiency in inhibiting common bacteria and fungi but also shows good effects against some microorganisms that are difficult to inhibit with traditional chemical antibacterial agents. Compared with traditional chemical antibacterial agents, Gleditsia sinensis thorns and the formulated antibacterial agent, based on natural plant extracts, significantly improve environmental friendliness and safety during use.

This invention discloses a high-strength, environmentally friendly, antibacterial particleboard and its preparation method, belonging to the field of novel functional artificial board technology. The particleboard utilizes a coordination reaction between 4-vinylbenzoic acid and rare earth lanthanum to construct a rare earth coordinated organic shell layer in situ on the surface of nano-copper oxide. Then, using a mercapto-ene click chemistry reaction, the vinyl-containing core-shell nano-copper oxide is covalently bonded and fixed onto mercapto-modified montmorillonite sheets. Stable liquid antibacterial agents are prepared by reacting these agents with sodium silicate solution and polyethylene glycol solution, respectively, and added to the core and surface particleboard. This not only achieves synergistic antibacterial and anti-leaching effects but also utilizes the alkalinity of sodium silicate to accelerate the curing of diphenylmethane diisocyanate in the core layer, achieving simultaneous curing of the core and surface layers of the board, thus improving the board's performance and environmental friendliness.

This invention relates to the field of antimicrobial peptide technology, specifically to an antimicrobial peptide for maintaining oral flora balance, its preparation method, and its application. The antimicrobial peptide for maintaining oral flora balance according to this invention includes any one of the following polypeptides (a)-(e): (a) a polypeptide whose amino acid sequence includes the amino acid sequence shown in SEQ ID NO. 1; (b) an amino acid sequence composed of amino acid residues shown in SEQ ID NO. 1; (c) a polypeptide formed by substituting and / or deleting and / or adding one or more amino acid residues to the amino acid sequence defined in (a) or (b); (d) a polypeptide having 99% or more, 95% or more, 90% or more, 85% or more, or 80% or more homology to the amino acid sequence defined in (a) or (b); (e) a polypeptide obtained by modifying the N-terminus and / or C-terminus of any one of the polypeptides defined in (a)-(d). The antimicrobial peptides of this invention, used to maintain oral flora balance, exhibit antibacterial and bactericidal activity against oral pathogens while not affecting the normal growth of beneficial bacteria. This balance is maintained, protecting gum health and freshening breath. These antimicrobial peptides are suitable for preparing oral antibacterial agents and related oral care products, regulating the balance of the oral microecology, and thus used to prevent and treat oral diseases, especially dental caries, periodontitis, oral mucosal diseases, and oral cancer. The antimicrobial peptides of this invention are relatively short, making chemical synthesis easier and allowing for direct synthesis into high-purity products. They also exhibit clear effects and have wide applications.

This invention provides a modified antibacterial polyurethane condom and its preparation method. The modified antibacterial polyurethane condom includes a polyurethane substrate layer and a functional coating. The polyurethane substrate layer includes a konjac glucomannan-polyurethane composite, a composite antibacterial agent, and modified nano-zinc oxide. The functional coating includes chitosan quaternary ammonium salt and hyaluronic acid. The chitosan quaternary ammonium salt in the functional coating is connected to the polyurethane substrate layer via covalent bonds formed through biocatalysis, and these covalent bonds are formed through the biocatalytic action of laccase. This modified antibacterial polyurethane condom exhibits low allergenicity, long-lasting antibacterial effect, and good mechanical properties.

The present application relates to a kind of bacteriophage lytic enzyme LysSPYS2, containing bacteriophage lytic enzyme composition and its application, bacteriophage lytic enzyme LysSPYS2 sequence is as shown in SEQ ID No.1, the bacteriophage lytic enzyme has high-efficiency, broad-spectrum bactericidal effect;It has lytic effect to a variety of bacteria, can be used as bacteriostatic agent;Further, the bacteriophage lytic enzyme is combined with polymyxin B, can exert synergistic antibacterial effect, significantly reduce the amount of antibiotic;The bacteriophage lytic enzyme can also be used with Magnolol, realize outstanding bacteriostatic effect.

The present application belongs to the field of preparation, and particularly relates to a compound emulsion and a preparation method thereof. The compound emulsion provided by the present application comprises the following components: simethicone, procaine hydrochloride, polyoxyl 40 stearate, glycerin monostearate, sodium carboxymethyl cellulose, a bacteriostatic agent, a pH regulator, a flavoring agent and water; wherein the content of the simethicone is 4 g%, the content of the procaine hydrochloride is 0.3%, the content of the polyoxyl 40 stearate is 0.8-1%, the content of the glycerin monostearate is 0.8-1%, and the content of the sodium carboxymethyl cellulose is 0.6-1.6%; the pH of the compound emulsion is 4.8-5.2, the emulsion droplet particle size D 10 is 1-3 microns, the emulsion droplet particle size D 50 is 3-6 microns, and the emulsion droplet particle size D 90 is 6-20 microns. The compound emulsion contains both the simethicone with defoaming capacity and the procaine hydrochloride with local anesthetic effect, and the emulsion has suitable particle size distribution and stable quality.

The present application relates to a kind of fish slice fresh-keeping toughening deployment method, which is sequentially prepared by fish slice pretreatment, composite fresh-keeping toughening deployment liquid, ultrasonic assisted infiltration, gradient wet heat protein shaping and vacuum deep cold storage process. The deployment liquid is compounded by edible salt, white granulated sugar, trehalose, composite phosphate, composite toughening regulator, crosslinking accelerator, natural antioxidant and bacteriostatic agent. After low-temperature ultrasonic infiltration of fish slice, wet heat pre-hardening, gradient cooling rearrangement, ice water quenching and repeated shaping are used in a step-by-step process, and protein structure solidification is completed under constant pressure. Through the synergistic effect of functional components and multiple processes, the present application can significantly reduce the thawing juice loss rate of fish slice, improve water holding capacity and texture toughness, inhibit fat oxidation and microbial reproduction, and keep the fish meat elastic and tough without being dry and tasteless. The present application effectively solves the technical defects of existing fish slice fresh-keeping and toughening.