13 results about "Anti-Microbial Agents" patented technology

The present invention relates to pyridine-2-thiol 1-oxide derivatives and their use as antimicrobial agents in infectious diseases of mammals (humans and animals) caused by fungi or bacteria, in particular belonging to the Mycobacteriaceae family, especially diseases caused by Mycobacterium abscessus or Mycobacterium tuberculosis.

Described herein are hydrogel-coated surgical meshes and their use in hernia repair, reconstructive surgery, and other surgical procedures. In one aspect, the hydrogel-coated meshes comprise at least one antibiotic or antimicrobial agent for the treatment of hernia repair surgery. In one aspect, the hydrogel coated meshes provide localized, sustained antimicrobial activity for the treatment of surgical site infections. In one aspect, the hydrogel coated meshes provide localized, sustained prophylactic antimicrobial activity for the prevention of surgical site infections. In another aspect, the hydrogel coating may optionally include one or more additional therapeutic components, such as anti-inflammatory compounds or growth factors, to facilitate and enhance recovery following hernia repair, reconstructive procedures, or other surgeries.

Provided herein are methods and compositions for modulating a microorganism's response to an antimicrobial agent. In one embodiment, the method comprises contacting the microorganism with an antimicrobial agent and bicarbonate. In one embodiment, provided herein are methods for treating a microbial infection comprising administering to a subject in need an effective amount of (i) bicarbonate and (ii) an antimicrobial agent. Also provided herein are methods of screening for antimicrobial compounds.

This invention provides a method and product for preparing a high-performance oil-based synthetic coolant, comprising: pretreatment, mixing polyalphaolefin, ester base oil, and synthetic ester in a mass ratio of 4:3:3 to obtain a composite base oil; pre-stirring and dispersion, including adding the pretreated composite base oil to a reaction vessel and stirring while simultaneously introducing an inert gas for protection; stepwise addition and reaction of additives, including sequentially adding a composite lubricating additive, a rust-inhibiting and anti-corrosion composite agent, an antioxidant, an antifoaming agent, and an antimicrobial agent; constant-temperature aging to obtain a mixture; purification and refining, under the protection of an inert gas, sequentially passing the aged mixture through a filter membrane for two-stage filtration; and final product testing, with the coolant passing performance testing being the high-performance oil-based synthetic coolant. This method is mild, simple to operate, and low in energy consumption, possessing environmentally friendly characteristics of low volatility and low pollution, meeting the stringent operating conditions of modern manufacturing.

The present invention concerns a new strain of an anti-Clostridium Lactiplantibacillus plantarum and its use for hard cheese protection as an antimicrobial agent.

The present invention primarily relates to the use of a mixture as defined herein as an antimicrobial agent. Moreover, it relates to a mixture as defined herein for use as an antimicrobial agent, to a personal care product, a pharmaceutical product, a home care product or an industrial or institutional cleaning product or a precursor thereof comprising one or more compound(s) of formula (I) as defined herein, and to a mixture comprising or consisting of (i) one or more compound(s) of formula (I) as defined herein and (ii) one or more further antimicrobial agent(s). Finally, it relates to a method as defined herein (i) for inhibiting or preventing the growth of one or more microorganisms on a mammal's skin, and / or (ii) for inhibiting or preventing the growth of one or more microorganisms in a personal care product, a pharmaceutical product, a home care product or an industrial or institutional cleaning product or a precursor thereof, and / or (iii) for inhibiting or preventing the growth of one or more microorganisms on / in a surface.

The invention relates to a compound of formula (I), a composition comprising the compound of formula (I) and a use of the compound of formula (I) as an antimicrobial agent. The invention also relates to a compound of formula (I) for use in treating a bacterial disease or infection in a subject, a method for treating a plant to control a disease, and a method for producing a compound of formula (I).

The present invention relates to compositions and methods for the use of polymerase chain reaction (PCR) as a reporter assay for rapid and simultaneous bacterial identification and phenotype testing for antimicrobial susceptibility (AST). The current invention uses a strategy that has shown the ability for multiplexing and for handling polymicrobial samples for antimicrobial susceptibility testing.

A composition is described comprising a polydiorganosiloxane; a silver material; and at least 1% by weight of an oxygen-containing metal filler of silicone, titanium, zirconium, or combinations thereof. The crosslinked composition may have a higher tensile strength than the same composition without the oxygen-containing metal filler. In some embodiments, the polydiorganosiloxane comprises a nonfunctional polydiorganosiloxane. In another embodiment, a method of manufacturing an adhesive article is described, comprising providing a layer of a polydiorganosiloxane composition on a substrate (e.g., a release liner), wherein the layer comprises a nonfunctionalized polydiorganosiloxane and a silver material; and subjecting the layer of the polydiorganosiloxane composition to radiation treatment, thereby crosslinking the layer of the polydiorganosiloxane composition.

A method of controlling an optical sensor exposed to a high-fouling water source from a food or beverage production operation can include introducing clean water into a flow chamber of the optical sensor. The optical sensor can measure an absorbance of the clean water and a cleanliness value can be determined based on the measured absorbance. If the cleanliness value is beyond a cleanliness threshold, a deep cleaning is performed on the optical sensor. Otherwise, if the cleanliness value is within the cleanliness threshold, a measurement sample from the food or beverage production operation can be introduced into the optical sensor and a concentration of an antimicrobial agent in the measurement sample determined.

Compositions and methods for reducing microbial population on the surface of whole raw materials to be used in ethanol production. Whole raw materials to be used in ethanol production may have surface contamination with microbial populations that can interfere with the ethanol production process. The compositions comprise one or more antimicrobials capable of reducing microbial population when applied to the surface of the whole raw material.

This invention belongs to the field of antifouling coating technology, and relates to a copper-free antifouling coating and its preparation method. The coating comprises a specific mass fraction of a resin mixture, an antimicrobial agent, fillers, additives, and a solvent. The specific steps are as follows: A specific mass fraction of the resin mixture, pigments, fillers, additives, and solvent is mixed and then dispersed for the first time to obtain a resin and pigment / filler mixture solution; subsequently, a specific mass fraction of the antimicrobial agent is added to the resin and pigment / filler mixture solution, and a second dispersion is performed to finally obtain the copper-free antifouling coating. The coating exhibits excellent antifouling effect and adhesion performance, and its low surface energy further enhances its anti-biofouling ability; simultaneously, its degradation products are all small molecules with good biocompatibility, which can be naturally decomposed in the marine environment without the risk of secondary pollution, meeting the green development needs of marine antifouling materials.

A composition for oral care is provided having a medium chain triglyceride, a hydrophobic anti-microbial agent, and a hydrophobic flavoring agent.