The invention relates to acne cream capable of effectively removing acnes and lightening acne marks. The acne cream comprises water, glycerinum, butanediol, a hamamelis virginiana extract, an aloe vera extract, neopentyl glycol diheptanoate, octanoic acid/capric acid triglyceride, meadowfoam seed oil, squalane, macadimia nut oil, butyrospermum parkii kotschy grease, nicotinamide polydimethylsiloxane, cetostearyl alcohol, cetearyl glucoside, sorbitan olivate, cetearyl olivate, sodium hyaluronate, dipotassium glycyrrhizinate, oligopeptides-1, arbutin, L-ascorbyl dipalmitate, a calendula extract,a lavender extract, an acroloyl-dimethyl taurine amino/VP copolymer, a sodium acrylate/acroloyl-dimethyl taurine sodium copolymer, isohexadecane, polysorbate-80, fullerene, an angelica sinensis extract, p-hydroxyacetophenone, 1,2-hexanediol, sweet orange flower oil and EDTA (Ethylene Diamine Tetraacetic Acid). The acne cream is prepared through a series of procedures and has the characteristics of good acne treatment effect, no acne mark, no side effect, and the like.