The invention discloses an anti-inflammatory and anti-aging body
lotion and a preparation method thereof, and relates to the technical field of
skin care products. The preparation method comprises the following steps: firstly, carrying out oxidation treatment on beta-
cyclodextrin by using
sodium periodate, and introducing an active
aldehyde group on a glucose unit of the beta-
cyclodextrin, so as to form
aldehyde beta-
cyclodextrin with a unique function; the cavity structure of the beta-cyclodextrin has efficient embedding capacity, and the hydrophobic coenzyme Q10 can be tightly wrapped in the beta-cyclodextrin; the preparation method comprises the following steps:
grafting adipic acid dihydrazide onto a
hyaluronic acid skeleton to form hydrazinized
hyaluronic acid with reaction activity; the
hyaluronic acid is subjected to specific cross-linking reaction with
aldehyde beta-cyclodextrin through hydrazino on the surface of the hyaluronic acid, a micro-
capsule structure with a dynamic
covalent bond-
hydrazone bond is formed, a three-stage
delivery mode of
stable storage, intelligent release and accurate action is formed, active ingredients can be effectively protected, intelligent release can be achieved according to the pH value characteristic of
skin, and the
skin care effect is achieved. The inflammatory reaction is relieved, and the anti-inflammatory and anti-aging effects are achieved. The body
lotion prepared by the invention has anti-inflammatory and anti-aging effects.