The invention relates to a method for cultivating coprinus comatua by utilizing fungus dregs in the edible fungus production field, which is characterized by utilizing the leftovers, namely fungus dregs, of the edible fungi instead of cottonseed hulls to cultivate the coprinus comatua, utilizing the method of biological fermentation to treat the fungus dregs and adding bran and other nutrients toform culture media, and effectively realizing cultivation of the coprinus comatua through the process flows of bagging, sterilizing, inoculating, hypha fermenting, cultivating, bag removing, soil covering, fruiting and harvesting, etc., wherein, the leftovers of the edible fungi are used for cultivating oyster mushrooms and needle mushrooms, etc. The method not only realizes resource of the organic wastes and reduces pollution of the organic wastes on the environment by developing and utilizing the leftovers of the edible fungi and conforms to the requirement on striving to develop circular economy encouraged by the state, but also greatly reduces the usage amount of the cottonseed hulls and other substances for cultivation, effectively lowers the production cost of the coprinus comatua, increases the cultivation benefits and ensures the biological conversion ratio to be more than 80%. The method utilizes the wastes and attains two objectives, thus being suitable for popularization andapplication in the rural areas.