This invention provides peony-shaped gold nanoparticles with an uneven core-shell structure, their preparation method, and applications. We first prepare 50 nm
diameter gold nanospheres, then add HAuCl₄, and perform
centrifugation and stirring to finally obtain the target product. This structure significantly improves
surface roughness and increases the distribution density of electromagnetic "hot spots" while ensuring good
particle stability, thereby enhancing the sensitivity of the SERS
signal.