2539 results about "Dermatology" patented technology

The invention relates to the technical field of cosmetics, in particular to an acne-removing composition, lipidosome and a preparation method and application thereof. The acne-removing composition disclosed by the invention is prepared from the following components in parts by weight: 2 to 8 parts of nicotinamide, 1 to 5 parts of cortex magnoliae officinalis extract, 0.15 to 2.01 parts of glycyrrhizic acid, 0.1 to 2 parts of totarol and 0.01 to 0.15 part of hyssopus officinalis extract. The nano-carrier is adopted to wrap and deliver the acne removal composition, so that the solubility of the functional components is increased, the bioavailability of the functional components is improved, meanwhile, the irritation of the functional components is also improved, multi-target co-delivery and multi-mechanism acne removal are realized, and the acne removal composition has a remarkable acne removal effect.

The invention provides application of a turbellarian worm extract in preparation of a product for promoting wound healing, a biological agent for promoting the proliferation activity and / or migration ability of fibroblast NIH3T3, a biological agent for improving the wound healing rate and the decrustation time and a biological agent for improving the collagen fiber deposition type in the wound healing process. The biological preparation is used for promoting regeneration of skin appendage organs in the wound healing process. Wherein the extraction of the turbellarian worm extract comprises the steps of turbellarian worm cleaning, tissue crushing, alcohol extraction, centrifugal separation and concentration drying. The turbellarian worm extract has good capacity of promoting wound healing, and has the effects of effectively improving skin wound healing efficiency, shortening decrustation time, inhibiting scar formation in the wound healing process, promoting regeneration of skin appendage organs in the wound healing process and the like.

The invention belongs to the technical field of cosmetic efficacy evaluation, and discloses a sunscreen efficacy evaluation method and application thereof, and the method comprises the following steps: building a blank group; establishing a model group; establishing a sample group; performing constant-temperature incubation on the blank group, the model group and the sample group for a first period of time, recording a swimming track, and calculating swimming distance increment and after-sun burning pain relieving efficiency of each group of zebrafish; performing constant-temperature incubation on the blank group, the model group and the sample group for a second duration, recording the tail fin and dorsal fin area of the zebra fish, and calculating the sunburn prevention efficiency; performing constant-temperature incubation on the blank group, the model group and the sample group for a third period of time, recording the head melanin area of the zebra fish, and calculating the anti-sunburn efficiency; and grading the sunscreen effect of the sample. The method disclosed by the invention has the advantages of low cost, short test period, high reproducibility, high visualization degree, intuitive and understandable test result and the like, and can be used for accurately grading the sunscreen effects of chemical sunscreen agents, water-soluble sunscreen cosmetics and raw materials thereof from the whole animal level.

The invention relates to the technical field of exosomes, in particular to an exosome compound preparation with a hair growing effect and a preparation method of the exosome compound preparation. Comprising 12 to 22 parts of ginsenoside Rb1, 15 to 12 parts of biotin tripeptide-15, 8 to 15 parts of diammonium glycyrrhizinate, 50 to 70 parts of fish collagen peptide, 10 to 20 parts of soybean peptide, 0.5 to 4.5 parts of SHH protein, 0.5 to 2.5 parts of SMO inhibitor, 0.5 to 1.5 parts of HhSP protein, 5 to 10 parts of N-acetyl tyrosine, 0.1 to 2 parts of hyaluronic acid, 0.1 to 1 part of melatonin, 0.1 to 1 part of quercetin, 0.1 to 1 part of kaempferol, 0.1 to 1 part of tanshinone, 0.1 to 1 part of biotin and 0.1 to 1 part of vitamin A. The compound preparation is combined with exosomes from various sources, so that the hair papilla cell function is synergistically enhanced, and the damaged hair follicle structure is repaired.

The invention provides an acne-removing composition containing ceramide, a preparation method of the acne-removing composition and an acne-removing product, and the acne-removing composition is prepared from the following components in parts by weight: 5 to 10 parts of plant extract, 1 to 3 parts of ceramide, 1 to 3 parts of gentiopicroside-vitamin C eutectic, 1 to 3 parts of compound polysaccharide and 0.3 to 0.7 part of transdermal enhancer. The plant extract is prepared from a herba dendrobii fruticosae flower extract, a lasiocarpus trifoliatus extract and a hedera rhododendron extract in a mass ratio of 1: (1-3): (2-4); the compound polysaccharide is prepared from tremella polysaccharide, tamarind seed polysaccharide and ganoderma lucidum polysaccharide in a ratio of 1: (3-5): (0.5-0.8); the transdermal enhancer is prepared from a cucumber extract and a salvia miltiorrhiza root extract in a mass ratio of 1: (1-3). The plant extracts in the acne-removing composition take effect synergistically, the acne-removing effect is achieved from multiple aspects of bacteriostasis, anti-inflammation and oil control, the purpose of efficiently removing acnes without relapse is achieved, and the natural plant extracts are mild and non-irritant, do not cause burden to the skin and have good application prospects.

The invention relates to a whitening and soothing composition, a nano microemulsion containing the same and a preparation method of the nano microemulsion. The whitening and soothing composition comprises a litchi fruit extract, a quercus root extract, a malt extract and palmitoyl tripeptide-5. According to the functional composition, the litchi fruit extract, the oak root extract, the malt extract and the palmitoyl tripeptide-5 are creatively combined for use, so that the functional composition has excellent skin whitening and soothing effects, and the four components have an obvious synergistic interaction effect in the aspects of whitening and soothing the skin; the functional composition can be widely applied to cosmetics with related functions. The nano micro-emulsion prepared from the functional composition is subjected to shearing emulsification and then high-pressure micro-jet treatment, so that the prepared nano micro-emulsion is better in stability and better in appearance property, and the nano micro-emulsion can stably play a role in whitening and relieving for a long time.

1. Name of the design product: Phototherapy Beauty Instrument (HY-80R). 2. Use of the design product: For phototherapy and beauty treatment of human skin. 3. Design key points of the design product: Lies in the shape. 4. Picture or photo that best shows the design key points: Perspective view.

The invention relates to the technical field of daily chemicals, and particularly discloses a scalp oil control composition for preventing alopecia seborrhoeica as well as a preparation method and application of the scalp oil control composition. The scalp oil control composition is prepared from the following main components: nicotinamide, capryloyl glycine, piralinone ethanolamine salt, betaine salicylic acid, lemon peel extract, white willow bark extract and rice fermentation filtrate. All the components have a synergistic effect, and the effects of controlling oil, protecting hair and preventing alopecia seborrhoeica are achieved. The preparation method disclosed by the invention is simple and convenient, and the obtained product is high in bioavailability of active ingredients, good in hair care effect and low in irritation, has the effects of caring hair, strengthening hair roots, regulating scalp micro-ecology and preventing seborrheic alopecia, and can be widely applied to related washing and care products for preventing seborrheic alopecia.

The invention pertains to the technical field of biomedical engineering and pharmacology and, without being limited thereto, specifically relates to a composition that enables the healing of full-thickness and chronic wounds (particularly in the foot region) observed in individuals suffering from diabetic disease.

The invention relates to a composition with antioxidant and brightening effects and capable of delaying skin saccharification as well as a preparation method and application of the composition, and belongs to the field of cosmetics. The composition comprises an ormosia henryi bark extract, tetrahydrocurcumin, a mirabilis jalapa extracting solution, a surfactant, polyol, phospholipid and a solvent. The composition provided by the invention has good illumination stability and high-temperature stability, and the composition provided by the invention is high in bioavailability, and has good antioxidant and brightening effects and lipofuscin and RAGE level inhibition effects.

The invention relates to composition of urolithins comprising urolithins and pectin and formulations of urolithins, specifically chewable formulations, comprising urolithins and a gelling agent. The invention further comprises compositions and chewable formulations comprising urolithins in combination with other active ingredients and processes for the preparation of such compositions and formulations. The invention further comprises methods of using such compositions and formulations in the treatment of conditions and diseases and for the promotion of health and performance, such in the improving muscle function.

The invention relates to the technical field of daily chemical industry, and discloses a moisturizing and soothing composition and application thereof.The moisturizing and soothing composition comprises, by weight, 20-25% of C14-16 sodium olefin sulfonate, 20-25% of C14-16 sodium alkyl sulfonate, 20-25% of C14-16 sodium alkyl sulfonate, 10-20% of C14-16 0.3%-0.7% of a cationic polymer; a litchi pericarp extract; an aloe extract; and a rosemary extract; wherein the total weight percentage of the litchi peel extract, the aloe extract and the rosemary extract is 1.9%-3.3%. The components are compounded, the cationic polymer and the anionic surfactant are utilized to construct a deposition system, and the three plant extracts with specific total content are cooperated, so that the retention rate of active ingredients in scalp is effectively increased, and the problem that moisturizing and soothing ingredients are easy to wash away is solved. The invention also provides a preparation method combining hot preparation and cold preparation, and the stability of the system and the activity of the extract are ensured by homogenizing the phase A at high temperature and adding the phase E at low temperature. The composition can be used for preparing shampoo products for moisturizing or relieving scalp.

The invention relates to the technical field of lipidosome compounds, in particular to a cosmetic lipidosome compound with an anti-allergy effect and a preparation method of the cosmetic lipidosome compound. The preparation method of the cosmetic liposome compound with the anti-allergy effect comprises the steps of preparation of a wrapping modification modifier, preparation of wrapping modification liposome and preparation of the cosmetic liposome compound. Efficient allergy relieving is achieved through the synergistic effect of the hovenia dulcis thunb extract and the white willow bark extract. The former inhibits release of inflammatory factors and scavenges free radicals, the latter reduces synthesis of prostaglandin and promotes epidermal renewal, and the former and the latter form a dual anti-inflammatory network, cooperate with lipid, regulate water and oil and accelerate inflammation regression. Meanwhile, the two extracts are wrapped by lipidosome, and a modifier formed by zein and fucoidin is combined, so that the stability of the lipidosome is enhanced, the percutaneous delivery efficiency and the percutaneous absorption effect of the components are improved through multiple effects, and it is ensured that the active components effectively exert the anti-allergy effect.

The present invention relates to the technical field of daily chemical technology, and specifically provides a whitening and freckle-removing cream. The freckle-removing cream comprises the following components in parts by weight: water, glycerin, mineral oil, antioxidant microcapsules, polydimethylsiloxane, sodium ascorbyl phosphate, niacinamide, a plant compound extract, essence, and cetearyl alcohol. The present invention adds natural plant extract ingredients, which is safe and effective. A circulation device is used to promote the effective combination of active ingredients, so that the active ingredients can quickly penetrate into the inner layer of the skin, thereby improving the transdermal absorption ability of the active ingredients. A unique encapsulation technology is used to firmly adhere the active ingredients to the skin surface, thereby effectively lightening facial spots, removing dullness from the skin, and restoring luster.

A low-cost, in-line process for treating a fibrous web with a lotion is provided. The process generally involves passing a web through a nip formed by a pair of opposed surfaces, where one of the surfaces has been treated with a lotion having a penetration hardness greater than 5.0 mm. As the web passes through the nip, the lotion is transferred from one of the opposed surfaces to the surface of the web. In certain instances, the web may have a textured surface and only a portion of the web's textured surface is treated with a lotion.

The present invention relates to the technical field of cosmetics, and discloses a whitening and freckle-removing essence and a preparation method thereof. The whitening and freckle-removing essence is formed by mixing additives such as nicotinamide, EDTA, L-lactic acid, citric acid, baicalein inclusion complex, etc. The baicalein inclusion complex has a coated structure. Since the skin surface carries a negative charge and the coating layer of the baicalein inclusion complex contains chitosan, it can be adsorbed on the skin surface through electrostatic action, producing a sustained-release effect, and then targeted release, so as to improve the whitening effect of the essence. In addition, after being encapsulated, baicalein can have good compatibility with other substances in the formula. Moreover, the linolenic fatty acid chain in the structure of the chitosan derivative has excellent antioxidant, anti-inflammatory and other effects, which can reduce the phenomenon of scar formation on the skin due to inflammation.

The instant disclosure relates to methods for removing color from artificially colored hair. The methods include a two-step process: (I) applying a reducing composition to hair that has been colored with oxidation dyes and rinsing the reducing composition from the hair; and (II) applying an alkalizing composition to the hair and rinsing the alkalizing composition from the hair. The step can be carried out in either order. The methods effectively remove color from artificially hair in a quick and gentle manner without employing an oxidizing agent.

A system for dispensing hair care formulations including a communication device that includes processing circuitry capable of taking a photo of a user's hair, uploading the photo into an application on a communication device, applying an algorithm to the photo to detect one or more hair features, sensing one or more environmental conditions with one or more sensors, and recommending a hair care treatment regimen of one or more hair care formulas based on the one or more hair features, and the one or more environmental conditions. The system also includes one or more cartridges containing one or more hair care formulas, and a dispensing device configured to dispense one or more hair care formulas from the one or more cartridges based on the hair care treatment regimen.

The invention provides a compound nystatin ointment and a preparation method thereof, and relates to the technical field of medicine preparation, the compound nystatin ointment comprises active ingredients of nystatin, neomycin sulfate, triamcinolone acetonide and permethrin, and the formula comprises liquid paraffin, white vaseline, wool fat, hexadecanol, PEG-30 dipolyhydroxystearate and glyceryl monoisostearate. According to the compound nystatin ointment preparation prescription process disclosed by the invention, the phenomenon of ointment matrix layering in the use process of commercially available products is mainly solved. According to a pharmaceutical research test, the stability of the compound nystatin ointment is superior to that of a commercially available original development agent, the ointment body character and the stability of active ingredients can be kept under the conditions of high temperature, high humidity, low temperature, freeze thawing and illumination, the maximum single impurity content and the total impurity content in the product are not obviously increased, and the quality is controllable. And meanwhile, an in-vitro transdermal test (IVPT) accidentally finds that the retention amount of related active ingredients is higher than that of the original development agent, and the drug effect is obviously improved. Through clinical test research, the compound nystatin ointment disclosed by the invention can be used for effectively treating external otitis caused by bacteria sensitive to neomycin, fungi sensitive to nystatin and ear mites sensitive to permethrin of dogs and cats.

The present invention relates to a functional cosmetic composition comprising plant exosomes derived from ginseng as an active ingredient and a functional cosmetic containing the same. Ginseng exosomes have a bilipid layer structure and are rich in ginsenosides Rb1 and Rg1, which influence skin improvement and whitening. It has been proven that these powerful functional materials, ginsenosides Rb1 and Rg1, are absorbed in large quantities through ginseng exosomes into skin cells, enhance the synthesis of collagen and hyaluronic acid in skin cells, and have the efficacy of inhibiting melanin synthesis. Therefore, the ginseng exosomes rich in ginsenosides Rb1 and Rg1, presented in the present invention, can be beneficially used in functional cosmetic compositions for skin aging prevention, skin whitening, wrinkle improvement and skin cell regeneration.

The invention relates to the technical field of cosmetics, and particularly discloses emulsion type foaming cleaning scrub cream with a skin care effect and a preparation method of the emulsion type foaming cleaning scrub cream. The scrub cream is prepared from the following raw material components in percentage by mass: 8 to 15 percent of glycerol, 0.2 to 0.9 percent of sodium hydroxide, 0.3 to 0.8 percent of citric acid, 0.03 to 0.2 percent of EDTA (Ethylene Diamine Tetraacetic Acid) disodium, 0.5 to 1.5 percent of an auxiliary agent, 1.5 to 3.0 percent of a thickening agent A, 1.5 to 3.0 percent of a thickening agent B, 5.86 to 1457 percent of an emollient, 12 to 22 percent of a surface active foaming agent, 0.8 to 3.0 percent of an emulsifying agent, 2.5 to 13 percent of a cutin stripping agent, 0.7 to 1.3 percent of a preservative, 0.32 to 0.92 percent of a skin conditioning agent and the balance of water, the skin conditioner is a mixture prepared from sodium hyaluronate, tocopherol, papain, nicotinamide, carnosine, panthenol and phytosterol oleate.

The present invention provides a Shatian pomelo white skin layer debitterizing technology, and belongs to the field of pomelo peel processing technologies, and the technology comprises the following steps: peeling and dicing a Shatian pomelo to obtain a Shatian pomelo white skin layer, debitterizing the Shatian pomelo white skin layer, soaking and rinsing the debittered Shatian pomelo white skin layer, and then drying to obtain a finished product. The Shatian pomelo white skin layer is used as a research object, the debitterizing rate and the sensory score are used as index values, the influence of a single debitterizing method (blanching, saline water and enzymolysis) and a composite debitterizing method (blanching saline water compounding and blanching enzymolysis compounding) on the white skin layer debitterizing effect is explored, and the result shows that the blanching saline water compounding debitterizing effect (hot water for 2 minutes, 4% salt soaking for 4 hours and clear water soaking for 1 hour) is optimal; at the moment, the debitterizing rate is as high as 80.1%, the sensory score is 90, and the treatment time is shortened by 29% compared with that of a single debitterizing method.

The invention relates to the technical field of skin care products, and discloses an anti-aging and whitening composition and a preparation method thereof.The anti-aging and whitening composition comprises anti-aging and whitening components, whitening synergistic components, moisturizing and repairing components and deionized water, and the anti-aging and whitening components comprise botryine, ergothioneine and Ectoine; wherein the mass ratio of the glassine to the ergothioneine to the ectoine is (1.2 to 2.0) to (0.4 to 0.7) to (1.0 to 1.5); the whitening synergistic component comprises one or more of nicotinamide, glabridin and tranexamic acid; the moisturizing and repairing component is prepared from one or more of sodium hyaluronate, ceramide NP, glycerol and 1, 3-butanediol. Experiments show that the mass ratio of the glassine to the ergothioneine to the ectoine is (1.2-2.0): (0.4-0.7): (1.0-1.5), so that the glassine, the ergothioneine and the ectoine show a remarkable synergistic effect (in some cases, the synergistic index CIlt is 0.85), and the anti-aging and whitening functions of the composition containing the glassine, the ergothioneine and the ectoine are improved.

The invention provides a soothing composition and application thereof in cosmetics, the soothing composition is composed of LIPOCIRE A PELLETS, Ectoine, a centella asiatica extract, Symcalmin, a purslane extract and panthenol, the composition utilizes a non-soothing component LIPOCIRE A PELLETS to be combined with a plurality of soothing active components, the action effect of each soothing component is fully exerted, human body tests show that the soothing composition has the effect of relieving the pain of a human body, and the soothing composition has the effect of relieving the pain of the human body. The composition can significantly improve the water content of the skin cuticle, reduce the skin transdermal water loss rate and the skin color a * value, and has significant synergistic effects in improving the moisturizing, repairing, soothing and other aspects of the soothing components.

The disclosure relates to compositions and methods for altering the color of hair, the compositions comprising at least one organic acid and / or a salt thereof, and at least one solvent.

The scar removing cream is prepared from the following raw materials in percentage by weight: 30 to 80 percent of silica gel component, 5 to 30 percent of solvent, 0.1 to 10 percent of emulsifying agent, 1 to 5 percent of thickening agent, 0.01 to 10 percent of extract / synergistic component, 0.1 to 20 percent of medicament component, 1 to 50 percent of moisturizing component, 0.01 to 0.1 percent of growth factor, 0.1 to 2 percent of other component, 0.01 to 0.5 percent of preservative and 0.1 to 2 percent of pH (Potential of Hydrogen) regulator. The traditional Chinese medicine composition has the effects of improving skin repair, whitening and diminishing inflammation, accelerates skin elasticity recovery and reduces scars.

The invention relates to the technical field of cosmetics, in particular to an efficient anti-aging composition and a skin care product containing the composition. The invention discloses an efficient anti-aging composition which is prepared from the following raw materials in parts by mass: 12-15 parts of oil-based concentrated active ingredients, 25-35 parts of base collagen liquid, 15-18 parts of Ectoine, 12-16 parts of TWEEN 20 and 22-25 parts of isosorbide dimethyl ether, and the oil-based concentrated active ingredients are prepared from safflower seed oil, an extract of flowers / leaves / stems of herba lysimachiae, an extract of radix astragali membranaci, ubiquinone and vitamin E; the base collagen liquid comprises XVII type collagen, VII type collagen and IV type collagen. Aiming at the problems that an existing skin care product cannot effectively reduce skin wrinkles, improve skin compactness, reduce skin sagging and prevent skin aging for a long time, the composition disclosed by the invention realizes long-term aging resistance from epidermis to dermis, effectively reduces wrinkles, improves compactness and improves skin sagging.

The invention relates to an anti-inflammatory and analgesic external composition, a preparation method and application thereof and a gel preparation, and belongs to the technical field of external pharmaceutical compositions.The anti-inflammatory and analgesic external composition is prepared from, by weight, 3-8 parts of loxoprofen sodium, 500-1000 parts of fried semen brassicae, 300-500 parts of fructus arctii and 10-30 parts of liquorice. The semen brassicae is warm in nature and pungent in taste, belongs to the lung channel, and has the effects of benefiting qi and removing stasis; the fructus arctii is cold in nature, pungent and bitter in taste, belongs to lung and stomach channels and has the effects of detoxifying and promoting eruption, the fructus arctii and the fructus arctii are cold in nature and warm in nature, mutual in medicine property, pungent and divergent in taste and have the effect of transdermal enhancement of the medicine effect, the liquorice is neutral in nature and sweet in taste, belongs to the heart, lung, spleen and stomach channels and has the effects of relieving spasm and pain and harmonizing all the medicines, and the liquorice, the fructus arctii and the liquorice can synergistically play the effects of stimulating menstrual flow and relieving pain. And with the cooperation of loxoprofen sodium, the synergistic interaction effect is achieved in the aspects of diminishing inflammation and relieving pain.

Provided are hair care formulations that protect the hair follicles and scalp of a subject from negative effects of hair dyeing. The hair care formulations include an antioxidant, a melanin stimulant, an anti-irritation component, a sebum modulator, a scalp repair component, and an anti-inflammatory agent. Several of these components are derived from natural sources, such as extracts from the roots of the Ononis spinosa flower, from mandarin orange fruit, and from seeds of the Schinus terebinthifolia tree. The formulations also include peptides used for melanin stimulation and scalp repair. Also provided are kits containing the scalp protection formulation, along with methods of using the scalp protection formulation. Also provided are formulations supporting hair pigmentation, hair growth, hair length, and hair health.

The invention discloses an anti-infection ointment for promoting healing of burns and scalds and other wound surfaces and a preparation method thereof, the anti-infection ointment comprises active components and auxiliary materials, the active components comprise 0.2-3 parts by weight of ganoderma lucidum chitosan, 0.2-5 parts by weight of recombinant III type collagen, 0.1-2 parts by weight of zinc and 0.5-8 parts by weight of a Cur-Mg compound; the Cur-Mg compound is a compound of Cur-Mg (at) PP hydrogel, antibacterial polyphenol and boric acid ester bond hydrogel. Compared with the prior art, the ointment disclosed by the invention has the advantages of good antibacterial property, high wound healing promoting speed, reduction of scar formation and the like through a synergistic effect of multiple components, and realizes slow release of active components and good wound microenvironment regulation through a hydrogel system.