1788 results about "Dermatology" patented technology

The invention relates to the technical field of cosmetics, in particular to an acne-removing composition, lipidosome and a preparation method and application thereof. The acne-removing composition disclosed by the invention is prepared from the following components in parts by weight: 2 to 8 parts of nicotinamide, 1 to 5 parts of cortex magnoliae officinalis extract, 0.15 to 2.01 parts of glycyrrhizic acid, 0.1 to 2 parts of totarol and 0.01 to 0.15 part of hyssopus officinalis extract. The nano-carrier is adopted to wrap and deliver the acne removal composition, so that the solubility of the functional components is increased, the bioavailability of the functional components is improved, meanwhile, the irritation of the functional components is also improved, multi-target co-delivery and multi-mechanism acne removal are realized, and the acne removal composition has a remarkable acne removal effect.

The invention relates to the technical field of exosomes, in particular to an exosome compound preparation with a hair growing effect and a preparation method of the exosome compound preparation. Comprising 12 to 22 parts of ginsenoside Rb1, 15 to 12 parts of biotin tripeptide-15, 8 to 15 parts of diammonium glycyrrhizinate, 50 to 70 parts of fish collagen peptide, 10 to 20 parts of soybean peptide, 0.5 to 4.5 parts of SHH protein, 0.5 to 2.5 parts of SMO inhibitor, 0.5 to 1.5 parts of HhSP protein, 5 to 10 parts of N-acetyl tyrosine, 0.1 to 2 parts of hyaluronic acid, 0.1 to 1 part of melatonin, 0.1 to 1 part of quercetin, 0.1 to 1 part of kaempferol, 0.1 to 1 part of tanshinone, 0.1 to 1 part of biotin and 0.1 to 1 part of vitamin A. The compound preparation is combined with exosomes from various sources, so that the hair papilla cell function is synergistically enhanced, and the damaged hair follicle structure is repaired.

The invention relates to a whitening and soothing composition, a nano microemulsion containing the same and a preparation method of the nano microemulsion. The whitening and soothing composition comprises a litchi fruit extract, a quercus root extract, a malt extract and palmitoyl tripeptide-5. According to the functional composition, the litchi fruit extract, the oak root extract, the malt extract and the palmitoyl tripeptide-5 are creatively combined for use, so that the functional composition has excellent skin whitening and soothing effects, and the four components have an obvious synergistic interaction effect in the aspects of whitening and soothing the skin; the functional composition can be widely applied to cosmetics with related functions. The nano micro-emulsion prepared from the functional composition is subjected to shearing emulsification and then high-pressure micro-jet treatment, so that the prepared nano micro-emulsion is better in stability and better in appearance property, and the nano micro-emulsion can stably play a role in whitening and relieving for a long time.

The invention relates to the technical field of daily chemicals, and particularly discloses a scalp oil control composition for preventing alopecia seborrhoeica as well as a preparation method and application of the scalp oil control composition. The scalp oil control composition is prepared from the following main components: nicotinamide, capryloyl glycine, piralinone ethanolamine salt, betaine salicylic acid, lemon peel extract, white willow bark extract and rice fermentation filtrate. All the components have a synergistic effect, and the effects of controlling oil, protecting hair and preventing alopecia seborrhoeica are achieved. The preparation method disclosed by the invention is simple and convenient, and the obtained product is high in bioavailability of active ingredients, good in hair care effect and low in irritation, has the effects of caring hair, strengthening hair roots, regulating scalp micro-ecology and preventing seborrheic alopecia, and can be widely applied to related washing and care products for preventing seborrheic alopecia.

The invention relates to composition of urolithins comprising urolithins and pectin and formulations of urolithins, specifically chewable formulations, comprising urolithins and a gelling agent. The invention further comprises compositions and chewable formulations comprising urolithins in combination with other active ingredients and processes for the preparation of such compositions and formulations. The invention further comprises methods of using such compositions and formulations in the treatment of conditions and diseases and for the promotion of health and performance, such in the improving muscle function.

The invention relates to the technical field of daily chemical industry, and discloses a moisturizing and soothing composition and application thereof.The moisturizing and soothing composition comprises, by weight, 20-25% of C14-16 sodium olefin sulfonate, 20-25% of C14-16 sodium alkyl sulfonate, 20-25% of C14-16 sodium alkyl sulfonate, 10-20% of C14-16 0.3%-0.7% of a cationic polymer; a litchi pericarp extract; an aloe extract; and a rosemary extract; wherein the total weight percentage of the litchi peel extract, the aloe extract and the rosemary extract is 1.9%-3.3%. The components are compounded, the cationic polymer and the anionic surfactant are utilized to construct a deposition system, and the three plant extracts with specific total content are cooperated, so that the retention rate of active ingredients in scalp is effectively increased, and the problem that moisturizing and soothing ingredients are easy to wash away is solved. The invention also provides a preparation method combining hot preparation and cold preparation, and the stability of the system and the activity of the extract are ensured by homogenizing the phase A at high temperature and adding the phase E at low temperature. The composition can be used for preparing shampoo products for moisturizing or relieving scalp.

The instant disclosure relates to methods for removing color from artificially colored hair. The methods include a two-step process: (I) applying a reducing composition to hair that has been colored with oxidation dyes and rinsing the reducing composition from the hair; and (II) applying an alkalizing composition to the hair and rinsing the alkalizing composition from the hair. The step can be carried out in either order. The methods effectively remove color from artificially hair in a quick and gentle manner without employing an oxidizing agent.

A system for dispensing hair care formulations including a communication device that includes processing circuitry capable of taking a photo of a user's hair, uploading the photo into an application on a communication device, applying an algorithm to the photo to detect one or more hair features, sensing one or more environmental conditions with one or more sensors, and recommending a hair care treatment regimen of one or more hair care formulas based on the one or more hair features, and the one or more environmental conditions. The system also includes one or more cartridges containing one or more hair care formulas, and a dispensing device configured to dispense one or more hair care formulas from the one or more cartridges based on the hair care treatment regimen.

The invention provides a compound nystatin ointment and a preparation method thereof, and relates to the technical field of medicine preparation, the compound nystatin ointment comprises active ingredients of nystatin, neomycin sulfate, triamcinolone acetonide and permethrin, and the formula comprises liquid paraffin, white vaseline, wool fat, hexadecanol, PEG-30 dipolyhydroxystearate and glyceryl monoisostearate. According to the compound nystatin ointment preparation prescription process disclosed by the invention, the phenomenon of ointment matrix layering in the use process of commercially available products is mainly solved. According to a pharmaceutical research test, the stability of the compound nystatin ointment is superior to that of a commercially available original development agent, the ointment body character and the stability of active ingredients can be kept under the conditions of high temperature, high humidity, low temperature, freeze thawing and illumination, the maximum single impurity content and the total impurity content in the product are not obviously increased, and the quality is controllable. And meanwhile, an in-vitro transdermal test (IVPT) accidentally finds that the retention amount of related active ingredients is higher than that of the original development agent, and the drug effect is obviously improved. Through clinical test research, the compound nystatin ointment disclosed by the invention can be used for effectively treating external otitis caused by bacteria sensitive to neomycin, fungi sensitive to nystatin and ear mites sensitive to permethrin of dogs and cats.

The present invention relates to a functional cosmetic composition comprising plant exosomes derived from ginseng as an active ingredient and a functional cosmetic containing the same. Ginseng exosomes have a bilipid layer structure and are rich in ginsenosides Rb1 and Rg1, which influence skin improvement and whitening. It has been proven that these powerful functional materials, ginsenosides Rb1 and Rg1, are absorbed in large quantities through ginseng exosomes into skin cells, enhance the synthesis of collagen and hyaluronic acid in skin cells, and have the efficacy of inhibiting melanin synthesis. Therefore, the ginseng exosomes rich in ginsenosides Rb1 and Rg1, presented in the present invention, can be beneficially used in functional cosmetic compositions for skin aging prevention, skin whitening, wrinkle improvement and skin cell regeneration.

The invention relates to the technical field of cosmetics, and particularly discloses emulsion type foaming cleaning scrub cream with a skin care effect and a preparation method of the emulsion type foaming cleaning scrub cream. The scrub cream is prepared from the following raw material components in percentage by mass: 8 to 15 percent of glycerol, 0.2 to 0.9 percent of sodium hydroxide, 0.3 to 0.8 percent of citric acid, 0.03 to 0.2 percent of EDTA (Ethylene Diamine Tetraacetic Acid) disodium, 0.5 to 1.5 percent of an auxiliary agent, 1.5 to 3.0 percent of a thickening agent A, 1.5 to 3.0 percent of a thickening agent B, 5.86 to 1457 percent of an emollient, 12 to 22 percent of a surface active foaming agent, 0.8 to 3.0 percent of an emulsifying agent, 2.5 to 13 percent of a cutin stripping agent, 0.7 to 1.3 percent of a preservative, 0.32 to 0.92 percent of a skin conditioning agent and the balance of water, the skin conditioner is a mixture prepared from sodium hyaluronate, tocopherol, papain, nicotinamide, carnosine, panthenol and phytosterol oleate.

The invention relates to the technical field of skin care products, and discloses an anti-aging and whitening composition and a preparation method thereof.The anti-aging and whitening composition comprises anti-aging and whitening components, whitening synergistic components, moisturizing and repairing components and deionized water, and the anti-aging and whitening components comprise botryine, ergothioneine and Ectoine; wherein the mass ratio of the glassine to the ergothioneine to the ectoine is (1.2 to 2.0) to (0.4 to 0.7) to (1.0 to 1.5); the whitening synergistic component comprises one or more of nicotinamide, glabridin and tranexamic acid; the moisturizing and repairing component is prepared from one or more of sodium hyaluronate, ceramide NP, glycerol and 1, 3-butanediol. Experiments show that the mass ratio of the glassine to the ergothioneine to the ectoine is (1.2-2.0): (0.4-0.7): (1.0-1.5), so that the glassine, the ergothioneine and the ectoine show a remarkable synergistic effect (in some cases, the synergistic index CIlt is 0.85), and the anti-aging and whitening functions of the composition containing the glassine, the ergothioneine and the ectoine are improved.

The disclosure relates to compositions and methods for altering the color of hair, the compositions comprising at least one organic acid and / or a salt thereof, and at least one solvent.

The invention relates to the technical field of cosmetics, in particular to an efficient anti-aging composition and a skin care product containing the composition. The invention discloses an efficient anti-aging composition which is prepared from the following raw materials in parts by mass: 12-15 parts of oil-based concentrated active ingredients, 25-35 parts of base collagen liquid, 15-18 parts of Ectoine, 12-16 parts of TWEEN 20 and 22-25 parts of isosorbide dimethyl ether, and the oil-based concentrated active ingredients are prepared from safflower seed oil, an extract of flowers / leaves / stems of herba lysimachiae, an extract of radix astragali membranaci, ubiquinone and vitamin E; the base collagen liquid comprises XVII type collagen, VII type collagen and IV type collagen. Aiming at the problems that an existing skin care product cannot effectively reduce skin wrinkles, improve skin compactness, reduce skin sagging and prevent skin aging for a long time, the composition disclosed by the invention realizes long-term aging resistance from epidermis to dermis, effectively reduces wrinkles, improves compactness and improves skin sagging.

The invention relates to a Kava pepper root extract with soothing, repairing and anti-wrinkle effects as well as a preparation method and application thereof, and belongs to the technical field of biological medicines and cosmetics. According to the method, hydroxypropyl-cyclodextrin and / or sulfobutyl-cyclodextrin are / is used as an extracting agent to fully extract the main functional component kavain in the kava pepper root powder, and a fat-soluble component kavain is clathrated by using the hydrophilicity and clathration effect of hydroxypropyl-cyclodextrin and sulfobutyl-cyclodextrin, so that the extraction efficiency of kavain is improved, and the yield of kavain is increased. The extract which contains the kavain and is soluble in water is obtained. The mixture of polyaluminum chloride and diatomite is used as an impurity removal agent to fully remove unstable components and pigments in the crude extract, and the prepared kavain extract has high purity and extraction rate, and has good solubility in water and good stability. The kava pepper root extract and the centella asiatica extract are combined to achieve a synergistic repairing effect, and the composition can be widely applied to the industries of biological medicine, cosmetics and the like.

The utility model relates to the technical field of beauty instruments, and particularly discloses skin care equipment which comprises a working head, the front end of the working head can be in contact with the skin, and the skin care equipment further comprises a radio frequency working module which comprises a plurality of electrodes and is used for outputting radio frequency current to the skin; the light working module comprises a light emitting device, and the light working module is used for emitting light rays with the wavelength ranging from 630 nm to 1940 nm; and the controller is electrically connected with the radio frequency working module and the optical working module and is used for outputting a control instruction for controlling the radio frequency working module and the optical working module to work simultaneously so as to perform light irradiation and radio frequency current action on the skin. Therefore, the controller outputs a control instruction for controlling the radio frequency working module and the optical working module to work simultaneously, so that the light irradiation and the radio frequency current effect can be carried out cooperatively. The synergistic effect can give play to the advantages of the two, and the skin care effect is enhanced.

To provide a topical skin preparation that effectively promotes collagen production within the skin, exhibits excellent usability, and effectively enhances post-use stratum corneum moisture content.SOLUTION: A topical skin preparation comprises niacinamide, a heparin-like substance, dipotassium glycyrrhizinate, a collagen peptide, a yeast extract, and glycylglycine. It is preferable that the topical skin preparation further contains hydrogenated soybean phospholipids and phytosterols. It is more preferable that the topical skin preparation has a niacinamide content of 5 mass% or more. It is also preferable that the topical skin preparation further contains at least one plant extract selected from Arnica montana and Plantago major.SELECTED DRAWING: Figure 1

Jammed oil-in-water emulsion toothpaste compositions. Jammed oil-in-water emulsion toothpaste compositions with unexpectedly high yield stress values and / or high opacity without the use of a solid opacifier. Jammed oil-in-water emulsion toothpaste compositions with a hydrophobic phase with a particular droplet size of from about 0.4 microns to about 1000 microns, which can lead to toothpaste compositions with unexpectedly high yield stress values and / or high opacity without the use of a solid opacifier.

A method of treating psoriatic arthritis in a patient by administering an IL-23 specific antibody, e.g., guselkumab, in a clinically proven safe and clinically proven effective amount and the patient achieves significant ACR20 / 50 / 70, PASI70 / 90 / 100, MDA, HAQ-DI, SF-36 PCS, MCS, LEI / dactylitis, PASDAS, GRACE, mCPDAI, DAPSA or RAPID3 improvement as measured 16, 24, 32, 40 and 48 weeks after initial treatment.

The invention provides a nomeline nasal-brain delivery preparation for transnasal region mucosa administration, and an auxiliary material mixture of the nasal-brain delivery preparation comprises 1) phospholipid, and 2) any one of diluent ethyl oleate, isopropyl myristate, sesame oil or castor oil; optionally, the auxiliary material mixture can also comprise 3) a dissolving agent such as ethanol or diethylene glycol monoethyl ether, the auxiliary material mixture is a non-aqueous system, and a solution prepared from the mixture of the two or three auxiliary materials can be absorbed by the nasal meatus olfactory mucosa after being administrated through the nasal region mucosa, can be quickly conducted to the brain olfactory bulb region along olfactory nerves and cerebrospinal fluid, and can be used for treating the brain olfactory bulb. The problems that the peripheral side effect is high due to poor brain targeting of the medicine, the medicine takes effect slowly and the like are solved.

The present invention relates to an extract of the above-ground part of plantago major, to a method for obtaining same, to cosmetic compositions containing same, and to various cosmetic uses.

The invention belongs to the field of cosmetics, and discloses an anti-wrinkle soothing composition, application of the anti-wrinkle soothing composition and a cosmetic. Comprising the following components in parts by weight: 15-20 parts of hydroxypropyl tetrahydropyrantriol, 10-15 parts of tetrahydromethylpyrimidine carboxylic acid, 5-10 parts of a leukocyte extract, 5-20 parts of a leontopodium alpinum callus extract solution and the balance of a bifidus yeast fermentation product filtrate, through reasonable compounding of the five components, synthesis of collagen and elastin can be effectively promoted, and good anti-wrinkle and soothing effects are achieved.

The invention discloses a spot-fading, whitening and skin-tightening composition and a preparation method thereof, and particularly belongs to the technical field of cosmetics. The composition is prepared from an extract of bark of the cissampelos maculata, hydroxyl pinacolone 9-cis-retinoate, sclareolide, tetrahydromagnolol and a quercetin dimer. The composition provided by the invention can significantly reduce the skin melanin content, improve the skin brightness and significantly improve the skin elasticity and compactness, all the components have a synergistic effect, the effects of spot fading, whitening and skin tightening are effectively achieved, the preparation process provided by the invention is stable and controllable, and the composition is suitable for large-scale production and has wide application prospects. A novel efficient skin care composition and an application scheme are provided for the field of cosmetics.

The invention belongs to the technical field of cosmetics, and relates to a multichannel multi-target accurate delivery anti-allergy soothing nano-composite and a preparation method and application thereof, glycyrrhizic acid, bisabolol, 4-tert-butyl cyclohexanol and hydroxyphenyl propionamide benzoic acid are selected as anti-allergy soothing functional components. Comprising the following raw materials in percentage by mass: 0.1-5wt% of glycyrrhetinic acid; 0.1 to 10 weight percent of bisabolol; 0.001 wt% to 1 wt% of 4-tert-butyl cyclohexanol; 0.01 to 1 wt% of hydroxyphenyl propionamide benzoic acid; 10 to 50 wt% of an emulsifier; 1 to 20 wt% of a liquid lipid; 1 to 10 wt% of a co-emulsifier; 10 to 30 wt% of a polyol; and the balance of water. The sum of the mass percentages of the components is 100%. According to different passages of different active ingredients, the four active ingredients are simultaneously loaded in the same composition, so that multi-passage and multi-target accurate delivery can be realized, the skin can be timely and efficiently relieved from the source, the uncomfortable symptoms of the skin can be solved, and the immunity of the skin can be improved.

The invention discloses a wet tissue liquid for improving hemorrhoid symptoms, a wet tissue, a production method and application, the wet tissue liquid comprises asiaticoside, a sophora flower charcoal extract, bisabolol, a honeysuckle flower extract, a rosemary extract, ceramide NP, D-panthenol, potassium cocoyl glycinate, citric acid, sodium citrate and purified water, and the wet tissue comprises spunlace non-woven fabric. The wet tissue liquid is loaded on a non-woven fabric, the production process of the wet tissue liquid comprises a pretreatment stage, a preparation stage and a filtering stage, and the produced wet tissue liquid is applied to hygienic products for improving hemorrhoid symptoms. The sophora flower charcoal extract is used for the haemorrhoids wet tissue liquid to achieve the effects of stopping bleeding, cleaning and mildly easing pain; double natural extracts are compounded to replace preservatives, traditional single symptom relief is upgraded to symptom treatment, mucous membrane repair and barrier protection, disease deterioration and recurrence risks are reduced, and the composition is free of chemical preservatives, free of irritant surface activity and suitable for being used by people with hemorrhoid symptoms.

The invention relates to a composition for preventing and improving skin aging and a cosmetic containing the same. The composition comprises a red rice extract and PDRN. The composition disclosed by the invention has a synergistic effect on promoting the generation of type I collagen, so that skin aging can be remarkably prevented and / or improved.

To provide a composition for hair capable of improving the volume of hair while suppressing the entanglement of hair, and to provide a hair treatment method using the composition for hair.SOLUTION: This composition for the hair is obtained by formulating (A) an amino acid-based cationic surface active agent with (B) one or more kinds selected from pantothenic acids, vitamin C or its salts, vitamin B3 or its salts and vitamin B6 or its salts. The hair treatment method uses the composition for hair.SELECTED DRAWING: None

Disclosed herein are devices, wound dressings and methods for determining the pH of fluid or a wound exudate at a wound. Example devices include a device comprising a surface configured to contact the fluid or wound and a pH indicator covalently bound thereto or applied to the surface, wherein the pH indicator has a first colour prior to contact with the fluid or the wound exudate and changes colour as a function of the pH of the fluid or wound exudate. Example devices include a device which indicates wound exudate loading within a wound dressing and wound dressing comprising an absorbent layer and a moisture indicator which indicates would exudate loading within the dressing, wherein the visibility of the moisture indictor changes as a result of a physical transformation of a first material within the dressing. Systems, devices, and methods are provided for monitoring wound status and progression by measuring pH levels indicated by pH-sensitive wound dressings. In some implementations, a wound is monitored by capturing an image of the pH-sensitive wound dressing and processing the captured image to determine the color of a pH indicator included on the wound dressing. The color of the indicator is determined in terms of RGB values from the image, and a pH value for the wound dressing is calculated from the dressing RGB values. The calculated pH value is then relayed to a user to be used as an indicator of wound status or health.