86 results about "Subcutaneous fat" patented technology

The invention discloses an endoscope pneumoperitoneum pressure system based on AI image evaluation and an intelligent adjusting method, and the method comprises the steps: 1, obtaining an original image of the abdominal cavity of a patient through CT equipment, carrying out the standardization processing of the original image, generating a standardized CT image data set, and constructing a three-dimensional dynamic model of the abdominal cavity of the patient based on an AI algorithm; in the second stage, quantitative analysis of subcutaneous fat thickness, visceral organ volume and operable space volume is carried out on the three-dimensional dynamic model by adopting an AI segmentation algorithm, and a personalized pneumoperitoneum pressure target value Ptarget and an adjustment threshold range are generated through a machine learning model in combination with basic illness state data of the patient; in the third stage, working data are collected in real time through a built-in sensor of the endoscope system, and the working data are input into the reinforcement learning model to dynamically calculate a pressure adjusting instruction delta P; through deep fusion of the AI technology and system closed-loop control, the intelligent level of the endoscope system is remarkably optimized, good hardware support is provided, and the function of optimizing the operation environment and effect is achieved.

The present invention features methods of manipulating subdermal fat in a treatment area. Such methods include inserting a needle (e.g., a micro-coring needle) through the dermis to the subdermal fat layer in order to excise a portion of tissue from the treatment area. These insertions result in a portion of the dermis and a portion of the subdermal fat to enter into the needle. Removal of the needle results in excision of the portion of dermis and subdermal fat that entered into the needle.

The near-infrared wearable subcutaneous fat metabolism monitoring device comprises a flexible substrate, a multi-wavelength NIR light source array, a photoelectric detector, a motion artifact suppression module, a wireless transmission unit, a fixing band and a photonic crystal enhanced detector, and the flexible substrate comprises a biocompatible layer, an optical window array and a pressure sensing layer. The wavelength of the multi-wavelength NIR light source array is 760nm / 850nm / 930nm / 980nm, the photoelectric detector is high-sensitivity InGaAs, the motion artifact suppression module is provided with an embedded signal processing module, the embedded signal processing module contains a motion artifact elimination algorithm, the wireless transmission unit is BLE5.0, the fixing band is connected with the flexible substrate, and the flexible substrate is connected with the fixed band. A first subcutaneous fat oxidation characteristic database based on time-frequency analysis is established by installing a fat oxidation dynamic fingerprint spectrum technology, FODS = summa 850980d [mu] a (lambda, t) dt.e-j2pif0tdt (f0 = 0.05 Hz) FODS = summa 850980dtd [mu] a (lambda, t). E-j2pif0tdt (f0 = 0.05 Hz), metabolic oscillation characteristics are extracted through wavelet-Hilbert transform, and a metabolic activity quantitative evaluation core algorithm WO2023 / 123456 is realized.

The application discloses a path planning method for subcutaneous deep layer injection of a mandible, which comprises the following steps: determining a target region of a subcutaneous deep layer which needs to be filled or improved in contour based on three-dimensional anatomical data of a mandible; the subcutaneous deep layer refers to a loose connective tissue gap between a subcutaneous fat layer and an upper periosteum layer; planning a main path which is substantially parallel to a baseline of a lower edge of the mandible or substantially coincides with a preset mandible contour line in the target region; the main path is located in the subcutaneous deep layer; planning a plurality of branch injection paths based on the main path; the starting points of the branch injection paths are distributed at intervals along the main path and extend alternately to the outside of both sides of the main path; and all the paths form a wheat ear-shaped topological structure with the main path as a central axis and the branch injection paths extending to both sides. The method effectively avoids excessive concentration of fillers in any dimension, thereby significantly reducing the swelling degree of local tissues caused by pressure concentration and being beneficial to shortening the recovery time.

The invention relates to the technical field of biology, in particular to a promoter with real skin specificity and application thereof. The promoter provided by the invention is selected from a promoter of any one or more of the following genes: GPN, FOS or APO. The promoter with true skin specificity provided by the invention can specifically express a target gene in dermis and remove off-target expression of liver and subcutaneous lipid membrane muscle at the same time, the promoter sequence is shorter than that of a broad-spectrum promoter, and the human hGPN promoter can be more safely applied clinically.

This invention discloses a selection method for meat geese that comprehensively considers feed conversion efficiency and subcutaneous fat properties, relating to the field of poultry genetics and breeding. The method includes the following steps: S1 determining feed conversion efficiency of meat geese; S2 determining subcutaneous fat properties of meat geese; S3 calculating the family mean values ​​for each trait; S4 analyzing the correlation and heritability of each trait; S5 constructing a comprehensive selection index for feed conversion efficiency and subcutaneous fat properties of meat geese; and S6 selecting breeding geese with high comprehensive selection indices. This invention utilizes individual measurements and single-cage determination of feed conversion efficiency in meat geese, establishes a three-point method for accurately measuring subcutaneous fat thickness, and constructs a comprehensive selection index for residual feed intake, subcutaneous fat percentage, and subcutaneous fat thickness. It provides a selection method that comprehensively considers feed conversion efficiency and subcutaneous fat properties in geese, simultaneously improving feed efficiency and reducing subcutaneous fat properties, achieving simultaneous selection and synergistic improvement of multiple traits, and significantly enhancing breeding efficiency.

The abdominal wall retractor for the observation hole of the laparoscope comprises a first retraction arm and a second retraction arm, the first retraction arm and the second retraction arm are hinged through a hinged shaft, and the first retraction arm comprises a first retraction arm front section, a first retraction arm middle section and a first retraction arm rear section. The end part of the rear section of the first retraction arm is fixedly connected with a first operation ring; the second retraction arm comprises a second retraction arm front section, a second retraction arm middle section and a second retraction arm rear section, the end part of the second retraction arm rear section is fixedly connected with a second operation ring, and the end part of the first retraction arm front section is movably connected with a first retraction rod and a second retraction rod; and the end part of the front section of the second retracting arm is movably connected with a third retracting rod and a fourth retracting rod. The utility model has the beneficial effects that the abdominal wall of the observation hole and the subcutaneous fat layer can be expanded, and the anterior sheath layer and the peritoneal layer can be better exposed, so that the peritoneal layer and the anterior sheath layer can be better sutured under direct vision, related complications of a puncture hole are avoided, the use is safe and reliable, and the operation time of medical personnel is saved.

The application discloses a kind of based on near infrared multiband detection abdominal fat distribution analysis device and method, it is related to fat analysis field, the spectrum of the information of subcutaneous adipose tissue (SAT) mainly reflected by close-range probe acquisition, accurate estimation is combined with pre-training model individualized subcutaneous fat profile parameter. Then, these parameters are used to drive an optical forward propagation model, dynamically predict and generate the SAT contribution spectrum of the individual at the remote probe. Finally, subtract this accurate prediction SAT contribution signal from the mixed spectrum collected by the remote probe, thereby effectively stripping the strong background noise. The signal-to-noise ratio of the residual spectrum obtained is significantly improved, and the visceral fat index can be accurately analyzed through a special correction model, solving the core technical problem that VAT cannot be measured due to SAT signal interference.

The present invention relates to a peptide having a lipolytic effect, and more particularly, to a composition for preventing, ameliorating or treating obesity comprising the peptide. The peptide having a lipolytic efficacy according to the present invention has excellent effects of reducing intracellular lipid droplets, reducing orange peel tissue, improving skin roughness, and reducing the interface length between dermis and subcutaneous fat layer, and can be used variously in the field of prevention, improvement, or treatment of obesity.

To provide a technology that can easily and stably provide a subcutaneous fat model having a well-developed subcutaneous fat layer and uniformly containing mature adipocytes. [Solution] A method for producing a subcutaneous fat model, comprising the step of culturing adipose stem cells or adipose progenitor cells by shaking them in a culture insert having a liquid-permeable membrane with a pore diameter of 3 μm or more at the bottom surface using a shaker, thereby producing a subcutaneous fat layer uniformly containing mature adipocytes.

The invention discloses an abdominal fat distribution analysis device and method based on near-infrared multi-band detection, relates to the field of fat analysis, and accurately estimates individualized subcutaneous fat profile parameters by combining a pre-training model through a spectrum which is acquired by a near-distance detector and mainly reflects subcutaneous fat (SAT) information. And then, driving an optical forward propagation model by using the parameters, and dynamically predicting and generating a due SAT contribution spectrum of the individual at the long-distance detector. And finally, subtracting the accurately predicted SAT contribution signal from a mixed spectrum collected by a long-distance detector, thereby realizing effective stripping of strong background noise. According to the residual spectrum obtained in this way, the signal-to-noise ratio of visceral fat (VAT) signals is remarkably increased, visceral fat indexes can be accurately analyzed through a special correction model, and the core technical problem that the VAT cannot be measured due to SAT signal interference is solved.

A PTH1 ligand-binding nucleic acid complex that is delivered to a target organ to regulate expression or editing of a target gene, or a transcription or translation product thereof is provided. The PTH1 ligand-binding nucleic acid complex includes a nucleic acid having an antisense strand with an oligonucleotide having a nucleotide sequence 12 to 30 nucleotides in length, complementary to a target transcription product, is bound to a PTH1 ligand. Such nucleic acid complexes are useful for the treatment of diseases caused by such a gene. The ligand-binding nucleic acid complex can be delivered to an organ, tissue, or cell in which the PTH1 receptor is expressed, such as the kidney, bone, and subcutaneous fat tissue, or the vascular endothelial cells. Thus, such nucleic acid complexes are useful for treatment of diseases in such organs.

The invention discloses a medical-grade transmission method blood oxygen ring which comprises a main board used for monitoring human body blood oxygen saturation data and a lithium battery used for providing a power source, the main board and the lithium battery are packaged on the inner side of an upper ring body and the inner side of a lower ring body respectively, and a power line is arranged at the output end of the lithium battery. The power line penetrates through the upper ring, the lower ring is installed on a power supply interface of the main board, a transmitting tube and a receiving tube are arranged at the two ends of the main board respectively, the transmitting tube is used for transmitting red light and infrared light to penetrate through a finger pulp to detect the oxyhemoglobin saturation, the receiving tube is used for receiving transmission light signals after penetrating through finger pulp tissue, and the transmitting tube and the receiving tube are distributed at an included angle of 110 degrees. According to the medical-grade transmission-method blood oxygen ring, a transmission-type method is adopted for penetrating through the finger pulp, the blood oxygen saturation degree is measured according to the intensity of transmission light attenuated after penetrating through the skin, the fat layer and the capillary bed, scattering interference of an optical signal by bone tissue and the subcutaneous fat layer is avoided, and the accuracy of a measurement result is improved.

The present application belongs to the field of livestock and poultry breeding and feed processing technology, and particularly relates to a feed additive, a nutritional supplement, a feed and application thereof. The present application provides application of p-coumaric acid in improving carcass and meat quality, improving feed conversion rate, reducing fat deposition of livestock and poultry and improving fat metabolism of livestock and poultry. The results of the examples show that p-coumaric acid can effectively improve the feed conversion efficiency of growing pigs in the growth stage, which provides a reference for reducing feed waste in production and realizing cost reduction and benefit increase of animal husbandry; under the premise of not reducing or even improving the growth performance and slaughter rate of growing and fattening pigs, the p-coumaric acid can reduce the fat thickness, improve the pig carcass rating, improve the meat quality, and is beneficial to realize efficient production of high-quality pork and improve the market competitiveness of pork in China; the p-coumaric acid can also reduce the blood lipids of chickens, reduce fatty liver and reduce subcutaneous fat deposition, maintain normal metabolism of chickens and improve the health of chickens.

The invention discloses a construction method of a spontaneous lupus adipositis animal model, which comprises the following steps: constructing keratinocytes with genotypes of PPAR [gamma] flox / flox- / -Krt5-CreERT < 2 + > / -Adipoq-Cre < + > / -and PPAR [gamma] flox / flox- / -Krt5-CreERT < 2 + > / -Adipoq-CreERT < 2 + > / -and fat cells into a conditional PPAR [gamma]-active receptor gamma gene knockout mouse, so as to construct the animal model with the spontaneous lupus adipositis animal model. Then knocking out PPAR gamma genes in keratinocytes and adipocytes by using a gene knockout activator, so that the mice spontaneously have the phenotypes of lupus septicaemia, including local skin unhairing, lipoatrophy, persistent skin lesion, proteinuria and serum autoantibodies; histological examination finds that lobular adipositis, glomerular volume increase, mesangial cell hyperplasia, inflammatory cell infiltration, glomerular IgG deposition and the like are mainly caused by dermal immune cell infiltration and subcutaneous fat layer lymphocyte infiltration, clinical symptoms of patients with lupus adipositis are simulated, and an important tool is provided for related research of lupus adipositis.

The invention discloses a method for constructing a prediction model for subcutaneous fat hyperplasia caused by insulin injection. The method comprises the following steps: S1, selecting a plurality of participants for questionnaire survey according to inclusion standards; s2, performing ultrasonic inspection on all participants; s3, performing feature screening on the predicted variables by adopting LASSO regression; s4, developing a fat hyperplasia prediction model by using three algorithms of random forest, extreme gradient lifting and logistic regression, and selecting the fat hyperplasia prediction model with the optimal performance for research; and S5, explaining the influence of the predictive variables on the fat hyperplasia prediction model through an SHAP method. According to the method, a machine learning-based insulin injection-induced fat hyperplasia prediction model is created, the constructed extreme gradient lifting machine learning model shows relatively high efficiency in the aspect of predicting the occurrence of fat hyperplasia of the diabetic patient, and the diabetic patient with high-risk fat hyperplasia can be accurately identified.

The application belongs to the technical field of poultry breeding, and discloses siRNA for targeted inhibition of chicken PLCD4 gene expression and application thereof; the siRNA comprises PLCD4-853, PLCD4-528 and PLCD4-1870; the siRNA for targeted inhibition of chicken PLCD4 gene expression can effectively reduce the expression of the chicken PLCD4 gene after being introduced into chicken primary subcutaneous adipocytes, and the inhibition efficiency is more than 50%, and the knockdown efficiency is very high; the siRNA can be used for identifying gene functions by specifically knocking down the expression of the chicken PLCD4 gene in vitro, and can be applied to genetic selection of high-quality broiler subcutaneous fat deposition as a molecular marker, and has great economic value and scientific research value.

The utility model discloses auxiliary equipment convenient for insulin injection, which relates to the technical field of medical assistance and comprises an equipment main body, a through hole is arranged above the back of the equipment main body, and a color distinguishing strip is connected above the outer surface of the equipment main body. Through the arrangement of the color distinguishing strip, the first distinguishing plate, the second distinguishing plate and the date distinguishing block, the seven iridescent colors on the color distinguishing strip correspond to the characters from the weekly one to the weekly day on the date distinguishing block respectively, and therefore the position needing to be injected on the day is determined, for example, insulin injection needs to be conducted in the weekly one; if not, a red color distinguishing strip is arranged or a date distinguishing block in a round-line shape is arranged, and insulin injection should be carried out on the left upper abdomen; according to the insulin injection device, mistaken injection, missed injection and mistaken injection of insulin injection can be reduced, subcutaneous induration caused by improper insulin injection of a diabetic patient is reduced, and complications such as infection, bruise and subcutaneous lipoatrophy of an injection part are reduced.

FIELD: plastic surgery.SUBSTANCE: under aseptic conditions and endotracheal anesthesia, hydropreparation of the subcutaneous fat tissue is performed with 0.04% ropivacaine solution 60.0 ml with adrenaline 1:100000, a skin incision in the area of the submammary groove of the mammary gland of 3.5–4.0 cm in length is made, the tissues are dissected layer by layer to the fascia of the pectoralis major muscle. A dissection is performed in the Chassignac space to the level of the lower pole of the areola or an incision is made in the skin in the area of the mammary gland along the lower semicircle of the areola, the tissues are perpendicularly dissected layer by layer to the fascia of the pectoralis major muscle. Next, dissection is performed in the Chassignac space to the level of the submammary groove, and the lateral edge of the right pectoralis major muscle is isolated. The retropectoral pocket for the implant is formed using blunt and sharp methods. The lower medial bundle of the pectoralis major muscle is mobilized to the level of 4 o'clock on a conventional clock dial for the right breast and to the level of 8 o'clock on a conventional clock dial for the left breast. Partial vertical myotomy of the free muscle flap is performed. The distal fragments of the pectoralis major muscle are fixed at three points to the posterior surface of the gland with an atraumatic Vikryl 2-0 thread at the level of the nipple-areolar complex. A silicone implant is placed into the formed pocket, and the implant is evenly distributed and centered within it.EFFECT: preventing uncontrolled cranialization of the pectoralis major muscle flaps during vertical myotomy in dual-plane augmentation mammoplasty.1 cl, 2 ex

The application discloses a prediction model of the risk of atherosclerosis of a type 2 diabetes patient and a construction method thereof, and the construction method comprises the following steps: obtaining general information, serum biochemical indexes and a brachial-ankle pulse wave velocity of the type 2 diabetes patient; calculating a ratio of visceral fat area and subcutaneous fat area of the patient; comparing the correlation of the general information and the serum biochemical indexes by using a single factor variance and a chi-square test method to obtain variables with statistical differences; determining influencing factors of the type 2 diabetes patient combined with atherosclerosis by using Spearman correlation analysis and multivariate logistic regression analysis; and constructing a logistic regression model: Logit (H) =-4.647+1.013*V / S+0.099*age-0.527*smoking+0.67*Hypertension-0.007*Cr, namely, the prediction model. The prediction model has good prediction performance and high clinical application value.

The use of a postbiotic of Bifidobacterium brevis 207-1 (GDMCC No. 60962) or a composition containing the postbiotic in the preparation of a medicine or a food product. The medicine or food product is used for preventing and / or ameliorating diseases and / or symptoms related to fat gain in a subject. The diseases and / or symptoms are selected from weight gain, obesity, fatty liver, fat accumulation (e.g., visceral fat accumulation and subcutaneous fat accumulation), abnormal lipid metabolism, or any combination thereof. The medicine or food product can promote the fat breakdown and / or inhibit the fat absorption, maintain or reduce the body weight and / or BMI of the subject, increase the satiety of the subject, and reduce the food intake of the subject.

The invention provides a biomarker for predicting the treatment response of an ovarian cancer patient to a VEGFR (vascular endothelial growth factor receptor) inhibitor and application of the biomarker, and finds that the fat volume of the ovarian cancer patient can be used as the biomarker for predicting the curative effect of the VEGFR inhibitor to tumors. Based on two markers of visceral fat volume and subcutaneous fat volume, an SAS trajectory analysis model is constructed, and clinical benefit people of an ovarian cancer VEGFR inhibitor treatment scheme are screened out; further in-vitro co-culture and in-vivo animal experiments prove that the existence of fat cells can specifically enhance the anti-tumor effect of the VEGFR inhibitor, and clinical correlation is explained from a biological mechanism; the invention provides a new tool and theoretical basis for realizing individualized precise medication of ovarian cancer targeted therapy.

The invention provides an intelligent ultrasonic body fat management system and method based on full-link data fusion, and relates to the technical field of digital health management. According to the system, an ultrasonic intervention module collects physical field coupling data and subcutaneous fat thickness data by utilizing a physical field sensing and in-situ measurement technology; the physiological monitoring module acquires whole body metabolic behavior data by using a physical sign tracking technology; the fusion decision module constructs a full-link fusion data set by using a space-time alignment technology, and identifies a dominant factor through a causal analysis algorithm to generate a feedback control instruction; and the execution response module analyzes the instruction by utilizing a self-adaptive control technology and generates physical field modulation output and interaction strategy window output. Through multi-dimensional data fusion and attribution closed loop, precise management from treatment perception and behavior tracking to software and hardware cooperative regulation is realized, and the problems of process black box and data island in the prior art are solved.

The invention discloses a force control method of a subcutaneous soft tissue surgical robot, which relates to the technical field of medical robots and comprises the following steps: acquiring a soft tissue ultrasonic echo data set, executing sound velocity calibration analysis, generating an actual sound velocity value, performing nonlinear correction on the actual sound velocity value by using a tissue viscoelasticity compensation factor, and outputting a real-time corrected sound velocity value. And performing thickness conversion according to the soft tissue ultrasonic image and the real-time corrected sound velocity value to obtain an actual fat thickness value, and performing differential operation on the actual fat thickness value and the zero pressure reference value to form a subcutaneous fat layering deformation quantity. According to the method, sound velocity calibration analysis and nonlinear correction are carried out on the soft tissue ultrasonic echo data set, meanwhile, the depth attenuation compensation model is constructed to carry out accurate modeling on the deep muscle correction deformation quantity, and controllability and safety of complex soft tissue operation in the operation process are improved.

The use of an RINL gene and an antagonist thereof in the treatment of obesity. Specifically provided is the use of an RINL gene or an encoded protein thereof. The RINL gene or the encoded protein thereof is used for one of the following: (1) as a marker for diagnosing, detecting or prognosing obesity; (2) in the preparation of a reagent or kit for diagnosing or detecting obesity; or (3) in the preparation of a drug for treating obesity. RINL-KO significantly improves glucose tolerance and insulin resistance of obese mice, ameliorates the accumulation of subcutaneous fat and visceral fat thereof, alleviates the inflammation of adipose tissue thereof, and greatly improves the health of the mice. Therefore, an RINL antagonist has the potential to efficiently treat obesity. It is proposed for the first time that RINL is used as a new target in the preparation of a drug for treating obesity, which is of great significance for new drug screening, and also provides a new idea for the treatment of obesity.

The invention discloses lignin-triiodothyronine self-assembled particles as well as a preparation method and application thereof. The lignin-triiodothyronine composite nano particles are prepared from lignin and triiodothyronine in a joint self-assembly mode. Experiments prove that single in-situ injection of the lignin-triiodothyronine composite nanoparticles can increase the expression of subcutaneous adipose tissues UCP-1 of normal diet fed mice and reduce adipose cells; single in-situ injection can increase the expression of subcutaneous adipose tissue UCP-1 of a mouse fed with short-term high-fat diet, reduce the weight of adipose tissue, increase the energy consumption of the mouse and improve the glucose tolerance of the mouse; multiple times of in-situ injection can improve obesity and fatty liver caused by long-term high-fat diet. The lignin-triiodothyronine composite nanoparticle provided by the invention has a good application prospect in treating, relieving or improving obesity or metabolic diseases related to the obesity.

This invention discloses a method for removing hair from animal skin suitable for food processing, belonging to the field of food processing technology. The method employs a two-stage process of "pretreatment + targeted hair removal." First, glycosidase pretreatment degrades the protein-polysaccharide complex in the intercellular spaces of the epidermal cells, clearing the permeation barrier without damaging subcutaneous fat. Then, charge adaptation technology is used, utilizing enzymatic hydrolysis to naturally lower the pH of the system. Initially, the enzyme molecules carry the same charge as the hair follicle permeation channels, enhancing permeation efficiency. Later, as the pH decreases, the charge of the enzyme molecules reverses, targeting and binding with the charge of the matrix surrounding the hair follicle, achieving hair removal. This method overcomes the limitation of two-sided permeation, achieving highly efficient one-sided permeation hair removal, avoiding the need for degreasing and preserving subcutaneous fat to the maximum extent. Furthermore, the process completely avoids the use of chemical additives that pose food safety risks or damage flavor. It offers high hair removal efficiency and minimal loss of skin collagen, providing a safe and efficient hair removal solution for animal skin food processing.

This invention discloses a microwave ablation handpiece with cryotherapy, comprising a handpiece body, a microwave radiation unit, a cooling circulation unit, a temperature sensor, and a control circuit. One end of the handpiece body is the operating end, and the handpiece body has an inner cavity. The microwave radiation unit is disposed in the inner cavity, and the microwave radio frequency unit is connected to an external microwave energy source via a radio frequency line to enable the microwave radiation unit to emit 2.45 GHz microwave energy. The cooling circulation unit has a cooling circulation chamber surrounding the microwave radiation unit, and the cooling circulation chamber can be vented into or drained with coolant. The temperature sensor is disposed in the inner cavity to sense the real-time temperature of the cooling circulation unit. The control circuit receives the temperature from the temperature sensor. With these features, it can selectively act on subcutaneous fat without damaging the epidermis and dermis; it can precisely control the temperature, ensuring that the temperature in contact with the epidermis is within a safe range; it has efficient energy penetration, shortening the treatment time per session; and it can operate for extended periods.

The invention relates to application of a horseradish tree leaf extract in preparation of fat-reducing medicines or functional foods, and belongs to the technical field of medicines. The application comprises the following steps that S1, mice are evenly divided into five groups according to the weight of the mice after being fed for one week under the conditions of constant temperature and humidity, each group comprises eight mice, and the five groups comprise a normal control Con group, a high-fat and high-cholesterol HFC model group, a low-dose moringa oleifera leaf extract L-MOL intervention group, a high-dose moringa oleifera leaf extract H-MOL intervention group and a positive drug rosiglitazone RSG intervention group; s2, except the normal control Con group, high-fat feed is administered to other groups, administration is performed in an intragastric administration mode at ten o'clock in the morning every day, the weight of the mice is observed and recorded, and continuous administration is performed for 60 days; s3, stopping taking medicine for 24 hours after the step S2, anesthetizing and sampling blood, dissecting after cervical vertebra dislocation and killing, dissecting the abdomen of the mouse, taking a picture, and recording the subcutaneous fat weight and the white fat weight of the abdomen of each group of mouse. The moringa oleifera leaf extract provided by the invention shows an excellent fat reducing effect.

The invention discloses a multispectral fusion warm needle moxibustion application depth and tissue response monitoring system, and belongs to the technical field of medical image processing and traditional Chinese medicine diagnosis and treatment assistance. The system comprises a multispectral image acquisition and adaptive registration module, a spectrum fusion and depth feature extraction module, an organization level response analysis and depth estimation module and a closed-loop feedback regulation and visual output module. Visible light, near infrared and thermal infrared spectrum images are synchronously collected, multi-scale spectrum fusion is carried out based on principal component analysis, multi-level thermal response accurate monitoring of subcutaneous tissue is achieved, tissue depth distribution is estimated through a deep learning network, a skin surface layer, a corium layer, a subcutaneous fat layer and a muscle fascia layer are divided, and the subcutaneous tissue is obtained. Thermal response parameters of each layer are calculated, a closed-loop feedback mechanism adaptively adjusts the collected parameters according to a monitoring result and optimizes moxibustion application suggestions, and standardized, precise and intelligent technical support is provided for needle warming moxibustion treatment.