21 results about "Subcutaneous fat" patented technology

The application discloses a path planning method for subcutaneous deep layer injection of a mandible, which comprises the following steps: determining a target region of a subcutaneous deep layer which needs to be filled or improved in contour based on three-dimensional anatomical data of a mandible; the subcutaneous deep layer refers to a loose connective tissue gap between a subcutaneous fat layer and an upper periosteum layer; planning a main path which is substantially parallel to a baseline of a lower edge of the mandible or substantially coincides with a preset mandible contour line in the target region; the main path is located in the subcutaneous deep layer; planning a plurality of branch injection paths based on the main path; the starting points of the branch injection paths are distributed at intervals along the main path and extend alternately to the outside of both sides of the main path; and all the paths form a wheat ear-shaped topological structure with the main path as a central axis and the branch injection paths extending to both sides. The method effectively avoids excessive concentration of fillers in any dimension, thereby significantly reducing the swelling degree of local tissues caused by pressure concentration and being beneficial to shortening the recovery time.

This invention discloses a selection method for meat geese that comprehensively considers feed conversion efficiency and subcutaneous fat properties, relating to the field of poultry genetics and breeding. The method includes the following steps: S1 determining feed conversion efficiency of meat geese; S2 determining subcutaneous fat properties of meat geese; S3 calculating the family mean values ​​for each trait; S4 analyzing the correlation and heritability of each trait; S5 constructing a comprehensive selection index for feed conversion efficiency and subcutaneous fat properties of meat geese; and S6 selecting breeding geese with high comprehensive selection indices. This invention utilizes individual measurements and single-cage determination of feed conversion efficiency in meat geese, establishes a three-point method for accurately measuring subcutaneous fat thickness, and constructs a comprehensive selection index for residual feed intake, subcutaneous fat percentage, and subcutaneous fat thickness. It provides a selection method that comprehensively considers feed conversion efficiency and subcutaneous fat properties in geese, simultaneously improving feed efficiency and reducing subcutaneous fat properties, achieving simultaneous selection and synergistic improvement of multiple traits, and significantly enhancing breeding efficiency.

A PTH1 ligand-binding nucleic acid complex that is delivered to a target organ to regulate expression or editing of a target gene, or a transcription or translation product thereof is provided. The PTH1 ligand-binding nucleic acid complex includes a nucleic acid having an antisense strand with an oligonucleotide having a nucleotide sequence 12 to 30 nucleotides in length, complementary to a target transcription product, is bound to a PTH1 ligand. Such nucleic acid complexes are useful for the treatment of diseases caused by such a gene. The ligand-binding nucleic acid complex can be delivered to an organ, tissue, or cell in which the PTH1 receptor is expressed, such as the kidney, bone, and subcutaneous fat tissue, or the vascular endothelial cells. Thus, such nucleic acid complexes are useful for treatment of diseases in such organs.

FIELD: plastic surgery.SUBSTANCE: under aseptic conditions and endotracheal anesthesia, hydropreparation of the subcutaneous fat tissue is performed with 0.04% ropivacaine solution 60.0 ml with adrenaline 1:100000, a skin incision in the area of the submammary groove of the mammary gland of 3.5–4.0 cm in length is made, the tissues are dissected layer by layer to the fascia of the pectoralis major muscle. A dissection is performed in the Chassignac space to the level of the lower pole of the areola or an incision is made in the skin in the area of the mammary gland along the lower semicircle of the areola, the tissues are perpendicularly dissected layer by layer to the fascia of the pectoralis major muscle. Next, dissection is performed in the Chassignac space to the level of the submammary groove, and the lateral edge of the right pectoralis major muscle is isolated. The retropectoral pocket for the implant is formed using blunt and sharp methods. The lower medial bundle of the pectoralis major muscle is mobilized to the level of 4 o'clock on a conventional clock dial for the right breast and to the level of 8 o'clock on a conventional clock dial for the left breast. Partial vertical myotomy of the free muscle flap is performed. The distal fragments of the pectoralis major muscle are fixed at three points to the posterior surface of the gland with an atraumatic Vikryl 2-0 thread at the level of the nipple-areolar complex. A silicone implant is placed into the formed pocket, and the implant is evenly distributed and centered within it.EFFECT: preventing uncontrolled cranialization of the pectoralis major muscle flaps during vertical myotomy in dual-plane augmentation mammoplasty.1 cl, 2 ex

The application discloses a prediction model of the risk of atherosclerosis of a type 2 diabetes patient and a construction method thereof, and the construction method comprises the following steps: obtaining general information, serum biochemical indexes and a brachial-ankle pulse wave velocity of the type 2 diabetes patient; calculating a ratio of visceral fat area and subcutaneous fat area of the patient; comparing the correlation of the general information and the serum biochemical indexes by using a single factor variance and a chi-square test method to obtain variables with statistical differences; determining influencing factors of the type 2 diabetes patient combined with atherosclerosis by using Spearman correlation analysis and multivariate logistic regression analysis; and constructing a logistic regression model: Logit (H) =-4.647+1.013*V / S+0.099*age-0.527*smoking+0.67*Hypertension-0.007*Cr, namely, the prediction model. The prediction model has good prediction performance and high clinical application value.

The use of a postbiotic of Bifidobacterium brevis 207-1 (GDMCC No. 60962) or a composition containing the postbiotic in the preparation of a medicine or a food product. The medicine or food product is used for preventing and / or ameliorating diseases and / or symptoms related to fat gain in a subject. The diseases and / or symptoms are selected from weight gain, obesity, fatty liver, fat accumulation (e.g., visceral fat accumulation and subcutaneous fat accumulation), abnormal lipid metabolism, or any combination thereof. The medicine or food product can promote the fat breakdown and / or inhibit the fat absorption, maintain or reduce the body weight and / or BMI of the subject, increase the satiety of the subject, and reduce the food intake of the subject.

This invention discloses a method for removing hair from animal skin suitable for food processing, belonging to the field of food processing technology. The method employs a two-stage process of "pretreatment + targeted hair removal." First, glycosidase pretreatment degrades the protein-polysaccharide complex in the intercellular spaces of the epidermal cells, clearing the permeation barrier without damaging subcutaneous fat. Then, charge adaptation technology is used, utilizing enzymatic hydrolysis to naturally lower the pH of the system. Initially, the enzyme molecules carry the same charge as the hair follicle permeation channels, enhancing permeation efficiency. Later, as the pH decreases, the charge of the enzyme molecules reverses, targeting and binding with the charge of the matrix surrounding the hair follicle, achieving hair removal. This method overcomes the limitation of two-sided permeation, achieving highly efficient one-sided permeation hair removal, avoiding the need for degreasing and preserving subcutaneous fat to the maximum extent. Furthermore, the process completely avoids the use of chemical additives that pose food safety risks or damage flavor. It offers high hair removal efficiency and minimal loss of skin collagen, providing a safe and efficient hair removal solution for animal skin food processing.

This invention discloses a microwave ablation handpiece with cryotherapy, comprising a handpiece body, a microwave radiation unit, a cooling circulation unit, a temperature sensor, and a control circuit. One end of the handpiece body is the operating end, and the handpiece body has an inner cavity. The microwave radiation unit is disposed in the inner cavity, and the microwave radio frequency unit is connected to an external microwave energy source via a radio frequency line to enable the microwave radiation unit to emit 2.45 GHz microwave energy. The cooling circulation unit has a cooling circulation chamber surrounding the microwave radiation unit, and the cooling circulation chamber can be vented into or drained with coolant. The temperature sensor is disposed in the inner cavity to sense the real-time temperature of the cooling circulation unit. The control circuit receives the temperature from the temperature sensor. With these features, it can selectively act on subcutaneous fat without damaging the epidermis and dermis; it can precisely control the temperature, ensuring that the temperature in contact with the epidermis is within a safe range; it has efficient energy penetration, shortening the treatment time per session; and it can operate for extended periods.

The application discloses a non-invasive continuous intra-abdominal pressure monitoring device and a monitoring method. The monitoring bag is provided with a U-shaped seat at both ends, and a tensioning assembly is arranged in the U-shaped seat. The two ends are connected with a waistband through mounting buckles, elastic buckles and connecting buckles. A cylindrical chamber with a ring-shaped pad and a diaphragm is arranged on one side of the monitoring bag, and is connected with an observation column with a scale. The cylindrical chamber is filled with low-viscosity silicone oil. The ring-shaped pad is used to tension the local skin to isolate the subcutaneous fat layer damping, and the intra-abdominal pressure drives the displacement of a piston plate in the observation column through the diaphragm and the silicone oil. A rotating adjusting bolt is used to change the distance between an elastic switch and the piston plate to set a threshold value. When the piston plate touches the switch, a buzzer alarm is triggered. An operating bolt is used to drive a rotating shaft and a steel wire pull rope to move a rectangular sliding block, so that the span of the mounting buckle is adjusted to regulate the binding tension. A ratchet and pawl pair is used to prevent the reverse loosening of the rotating shaft, and the locking can be released by pressing a pressing block. The application avoids the boundary relaxation caused by tissue creep and the transmission loss caused by fat damping, and accurate continuous intra-abdominal pressure monitoring data is obtained.

Embodiments of the present application relate to a pedicle screw loosening evaluation method and device based on no phantom QCT bone density measurement. The method comprises: acquiring quantitative computed tomography (QCT) image data of a lumbar vertebra of a patient; based on a no phantom calibration technology, performing bone density calibration and measurement on CT values of paraspinal muscles and subcutaneous fat in the lumbar vertebra QCT image data; segmenting a vertebral body region and a pedicle screw channel region of the CT image sequence of the patient through a preset neural network model; determining the bone density of the pedicle screw channel region, combining with finite element biomechanical analysis to evaluate the pull-out force of the pedicle screw implantation; and determining a risk level according to the pull-out force and a preset loosening risk evaluation rule. The technical solution of the embodiments of the present application can evaluate the risk of postoperative screw loosening, pull-out and other complications without relying on external phantoms to evaluate local bone density.

This invention proposes a CT medical image processing and recognition method and system for sarcopenia. The method includes: acquiring CT images and performing image preprocessing; establishing a task-driven closed-loop fitness function based on sarcopenia pathological image feature enhancement parameters, and using an adaptive particle swarm optimization algorithm to enhance sarcopenia pathological features; using a multi-scale adaptive Gaussian filter combination to enhance the edges of the adaptively enhanced image, and using a segmentation model for pixel-level segmentation to identify and locate the image regions corresponding to skeletal muscle, subcutaneous fat, and visceral fat. This invention combines traditional particle swarm optimization with an adaptive optimization strategy targeting sarcopenia features. It can automatically adjust the enhancement strategy according to image contrast and noise level, and with multi-scale adaptive Gaussian filtering, intelligently enhance muscle edges according to tissue density, clearly distinguishing skeletal muscle from fat and viscera, and improving the problem of inconsistent image quality under different original image acquisition conditions.

A method for reducing a subcutaneous fat deposit or a visceral fat deposit in vivo by contacting the fat deposit with a composition of latanoprost encapsulated in a liposome formed solely of egg phosphatidylcholine (EggPC) or palmitoyloleoyl phosphatidylcholine (POPC). Also disclosed are methods for treating steatoblepharon, proptosis, and obstructive sleep apnea associated with excess upper airway fat by injecting into the eyelid, intraconal space, and upper airway fat deposit, respectively, the composition of latanoprost encapsulated in an EggPC or POPC liposome.

Disclosed catheter insertion systems enable the user to identify the location of the needle based on the electrical properties of subcutaneous tissue relative the electrical properties of other fluids such as blood or air. Disclosed systems can include one or more of the following features: 1) the catheter assembly is modular (e.g., the catheter can be connected and disconnected from the detection unit at will); 2) the detection unit employs an electrical circuit that allows for the discernment between subcutaneous tissue and blood; 3) the system assists the end user with catheter advancement. Some embodiments can be used to insert catheters into a spaces where the needle passes first through subcutaneous fat and muscle before entering fluid or air.

FIELD: medicine.SUBSTANCE: invention relates to simulators for practicing skills of applying surgical sutures to the skin and techniques of tying surgical knots. The simulator includes a multi-layer cushion simulating human tissues, a simulation of vessels in the tissues, and has a rectangular shape with rounded edges measuring 20 by 15 cm and a height of 1.8 cm. The simulator is made of hypoallergenic polymers and contains four layers simulating human tissues - epidermis, dermis, subcutaneous fat, muscles. Vessels of various diameters, filled with a liquid imitating blood, run in the subcutaneous layer. A flap of PVC artificial leather having a skin texture, treated with liquid release wax IZHWAX SP, is placed on a platform with legs measuring 25 by 20 cm. A part in the form of a side 1.75 mm high, printed on a 3D printer, is placed on the flap. A nylon stretch mesh with a density of 110 g / m2 is stretched over the part. The stretch mesh is fixed to the platform with clamps. A part in the form of an outer side with 'ears' 17 mm high, printed on a 3D printer, is installed on the mesh. The entire structure is completely pressed against the base using clamps so that the nylon mesh remains stretched. Platinum silicone rubber of appropriate parameters is poured into a separate container. The components are mixed and coloured with a dye for epoxy resin, and after the last layer hardens, all the existing 3D-printed sides and other parts are separated. The excess stretch mesh is cut off.EFFECT: possibility of performing training of intramuscular injection, layer-by-layer dissection of the simulator layers with a scalpel down to the underlying layers and applying sutures in hard-to-reach places, in particular on the muscle layer, fascia, aponeurosis.1 cl, 1 dwg

The present application belongs to the field of medical devices and physiological signal detection technology, and relates to a pulse wave analysis method and system based on piezoelectric dynamics characteristics. The present application compensates for the attenuation of the subcutaneous tissue on the pulse wave through active acoustic detection, emits high-frequency mechanical vibration waves at the end of diastole using multi-frequency voltage pulses, and receives reflected echoes to construct an equivalent acoustic impedance transfer function and an acoustic inverse compensation filter. The present application restores the true arterial vessel wall dynamics by performing frequency domain deconvolution operation on the original pulse wave signal, locates key physiological event points, estimates the local pulse wave propagation speed using a single-point piezoelectric sensor without the need for multi-point measurement. In combination with the fluid mechanics equation, the present application separates the forward incident wave and the backward reflected wave, calculates the absolute amplitude ratio to evaluate the vascular compliance, effectively eliminates the interference of subcutaneous fat and muscle tissue, improves the accuracy and reliability of the evaluation, and provides a new tool for cardiovascular function evaluation.

Cosmetic composition comprising a conjugated compound consisting of a hexyl secondary alcohol, a polyether organic polymer and, optionally, a C2-C22 hydrocarbon chain, saturated or unsaturated, cis or trans, linear or branched, with at least two carboxyl groups and its use for removing subcutaneous fat deposits.

This invention provides a deep learning-based fat and muscle segmentation method and system based on Slicer, applied in the field of data processing technology. This application preprocesses preoperative CT image data of the target patient to generate skeletal muscle image features, subcutaneous adipose tissue image features, and visceral adipose tissue image features; preprocesses the training sample set, adjusting window width and level and normalizing it to generate target training image data; trains a pre-defined fat and muscle segmentation model based on a deep learning network using the target training image data to generate a target fat and muscle segmentation model; processes the skeletal muscle image features, subcutaneous adipose tissue image features, and visceral adipose tissue image features based on the target fat and muscle segmentation model to generate target image segmentation information; and processes the target image segmentation information and the target patient's gene detection information to generate preoperative warning information for the target patient.

This invention proposes a method for analyzing muscle tissue in sarcopenia patients based on CT images. The method includes acquiring abdominal CT images of the same subject; performing pixel-level segmentation on the preprocessed CT images to distinguish and locate muscle, subcutaneous fat, and visceral fat regions; calculating changes in area and / or volume of each tissue and changes in HU value based on the output results of the same subject at different time points; performing longitudinal quantitative analysis and comparison based on a timeline; and outputting visualized labeled results. This invention assesses the tissue regions and changes of three core components: muscle, subcutaneous fat, and visceral fat. It quantifies the assessment results using multiple dimensions such as pixel count, actual physical area or volume, grayscale density, and standard deviation. The assessment is comprehensive, objective, and repeatable, meeting the needs of precise clinical assessment. It can intuitively identify key pathological changes such as muscle loss and fat infiltration, providing a reliable basis for early intervention.

The application discloses a special device for abdominal cavity opening suture, and belongs to the technical field of medical instruments. The device aims to solve the problems of traditional suture instruments, such as difficult closure of the inner incision, risk of mis-suture of adjacent organs, lack of real-time tension feedback and visual guidance function, and the like, in patients with thick subcutaneous fat tissue due to the limited depth of entry. The device comprises a guide sheath, a puncture execution mechanism and a tissue clamping assembly. The device realizes non-axial puncture through the deflection outlet and the arc transition section, the tissue clamping assembly clamps the inner incision edge, and the double-line loop suture structure enhances the gripping force, so that accurate operation can be guided and ensured and organ damage can be avoided. The suture device can effectively improve the accuracy, safety and standardization degree of abdominal wall suture of patients with thick fat layer, and reduce the risk of postoperative complications.

This invention relates to the field of medical testing device technology, and particularly to a signal acquisition and processing system and method for a multi-reaction zone implantable sensor. The signal acquisition and processing method for a multi-reaction zone implantable sensor is characterized by the following steps: S10: Retrieving stored clinical sample data, extracting subcutaneous fat layer depth range data for different users from the clinical sample data, and performing fusion analysis on the subcutaneous fat layer depth range data for all users. This invention employs a dual adaptation principle of constructing a universal range using clinical data and real-time detection to lock onto individual fat layer depth. Combined with a stable sensor fixation design, it automatically filters effective electrical signals from the target area and converts them into detection results. This solves the problems of high operational difficulty, cumbersome steps, and low user experience when relying on users to independently adjust the sensor implantation depth. Simultaneously, it adapts to individual differences and acquisition location variations, meets the needs of special populations, and improves detection accuracy and convenience.

This invention provides the application of fuscin acid in the preparation of weight loss, lipid reduction, and metabolism improvement products, offering a new use for fuscin acid. It can effectively reduce subcutaneous fat weight, decrease the whitening degree of brown adipose tissue, reduce the size of adipocytes in visceral adipose tissue, improve the fatty liver phenotype, improve glucose tolerance, and reduce serum TG and TC levels, without affecting the weight of brown adipose tissue and muscle tissue, providing an effective solution for safe and effective weight loss using traditional Chinese medicine extracts.