The invention discloses a mobile multifunctional health examination all-in-one machine. The all-in-one machine comprises a worktable, a main unit box, a base, an advertisement screen, a sphygmomanometer, a fat measurement handle, a storage box, a printer, an electrocardio box, a touch screen, a thermometer, a controller, a glucometer and an oximeter. The advertisement screen and the touch screen are connected into a whole to form an integrated structure, the touch screen and the sphygmomanometer are both installed on the worktable, and the fat measurement handle is installed on a front panel of the main unit box; the electrocardio box is arranged on a side panel of the main unit box, and an electrocardiograph is arranged in the electrocardio box; a thermometer box is arranged at the left edge of the worktable; two concave cavities where the glucometer and the oximeter can be placed are embedded in the worktable; the storage box is arranged in the middle of the front panel of the main unit box, the printer is arranged in the storage box, and the controller controls the printer to print health examination reports of users. The all-in-one machine has the advantages of integrating multiple functions, being high in integration degree and automation degree and convenient to move and the like.