7 results about "Liver fat" patented technology

The present application belongs to the field of nutritional composition and biological medicine technology, and particularly relates to a composition for protecting and preserving liver, a preparation method, application and product thereof. The composition of the present application is composed of extract of Silybum marianum, glucoraphanin and extract of Cynara scolymus. The composition of the present application can intervene the pathological process of liver injury from multiple dimensions such as antioxidation, anti-inflammation, regulation of lipid metabolism and repair of hepatocytes through synergistic effect of the three components, significantly reduces the levels of glutamic-pyruvic transaminase and glutamic-oxalacetic transaminase, reduces the accumulation of liver fat, improves the antioxidant capacity of the body, effectively prevents or improves alcoholic, chemical, non-alcoholic fatty and autoimmune liver injury, delays the progression of liver fibrosis, and comprehensively maintains the structural integrity and functional stability of the liver.

The present application discloses the use of FGF21 / GLP-1 fusion proteins in the preparation of a medicament for preventing and / or treating at least one of type 2 diabetes, obesity, steatohepatitis, and triglyceridemia. The FGF21 / GLP-1 fusion proteins of the present application are effective in treating at least one of type 2 diabetes, obesity, steatohepatitis, and triglyceridemia, and in particular, can reduce at least one of HbA1c, blood glucose, body weight, liver fat content, ALT, AST, glutamyl transpeptidase, triglyceride, total cholesterol, low-density lipoprotein cholesterol, or increase at least one of adiponectin, insulin sensitivity, and beta-cell function in the subject.

The application provides an application of ursodeoxycholic acid in preparation of an environmental stress induction caused fish disease related product, and the application comprises one of the following: an application in preparation of a drug for preventing an environmental stress induction related fish disease; an application in preparation of a drug for reducing, treating or assisting in treating an environmental stress induction related fish disease; and an application in preparation of a feed, a feed raw material, a feed additive or a feed composition for improving an environmental stress induction related fish disease. The application proves by experiments that adding a certain dose of ursodeoxycholic acid in the feed can significantly relieve pathological damage of liver of crucian caused by environmental stress factors such as ammonia nitrogen and nitrite, including reducing hepatocyte vacuolization, karyopyknosis and inflammatory cell infiltration, and reducing pathological deposition of liver fat.

The present application relates to the field of medicine, and particularly relates to a traditional Chinese medicine composition for preventing, treating and improving non-alcoholic fatty liver, alcoholic fatty liver and obesity and application thereof; the composition is composed of chuanqiong, xiangfu, mayi, jineijin, baizhi, baicaoren, aloe or dahuang, cheqiancao, chixiaodou, meigui, yujin, wumei, biejia, zhizi and taizishen, based on the compatibility concept of "warm and hot dissolving, multi-target intervention", a three-dimensional treatment network of soothing liver and regulating qi, regulating qi and eliminating stagnation, moistening the intestines and defecation, promoting blood circulation to soften the liver and clearing heat and invigorating the spleen is constructed; the composition can be made into various oral preparations, and the animal test proves that the composition can effectively reduce liver fat deposition, improve liver function and related metabolic indicators, and has high safety, and is suitable for long-term conditioning.

This invention belongs to the field of traditional Chinese medicine preparations, specifically relating to a traditional Chinese medicine composition for weight loss, its preparation method, and its application. The traditional Chinese medicine composition of this invention is made from the following raw materials in parts by weight: 15-25 parts Angelica sinensis, 8-12 parts Astragalus membranaceus, 8-12 parts Citrus reticulata peel, and 8-12 parts Nelumbo nucifera leaf. In this invention, Angelica sinensis is the principal herb, promoting blood circulation and unblocking collaterals; Astragalus membranaceus is the assistant herb, tonifying qi and promoting digestion; Citrus reticulata peel is the adjuvant herb, regulating qi and resolving phlegm; and Nelumbo nucifera leaf is the guiding herb, clearing heat and promoting diuresis. The entire formula works synergistically to resolve phlegm, promote diuresis, strengthen the spleen, and soothe the liver. Animal experiments have shown that the composition of this invention can significantly reduce weight gain, fat accumulation, and liver fat content in obese mice, improve oral glucose tolerance, and reduce serum triglyceride and low-density lipoprotein cholesterol levels. At the same time, it can significantly restore the diversity of intestinal flora α, increase the abundance of beneficial bacteria and reduce the abundance of harmful bacteria, effectively improve the intestinal flora disorder induced by a high-fat diet in mice, and the remodeled intestinal flora can play a role in weight loss. Thus, this invention provides a safe, effective, and palatable new traditional Chinese medicine compound solution for metabolic disorders and intestinal microecological imbalance.