53 results about "Liver parenchyma" patented technology

The invention discloses a full-automatic ultrasonic liver fat content detection method and system based on double nakagami. The method comprises the following steps: S1, acquiring a B-mode image of an ultrasonic liver and IQ envelope data of an original RF signal; s2, carrying out image segmentation on the B-mode image through a deep learning segmentation method, and segmenting liver parenchyma and blood vessel regions in the image; s3, performing post-processing on a result after image segmentation to obtain a candidate curved-edge trapezoid ROI region only containing liver parenchyma; s4, inputting IQ envelope signal position area data corresponding to the candidate ROI area into a double-nakagami mixed distribution model, and estimating and optimizing model parameters through an algorithm to obtain the fat content in the specified ROI area; according to the invention, full-automatic quantitative detection of the ultrasonic liver fat content is realized, and a doctor or a user is helped to complete detection of the liver fat content on the premise of not depending on ultrasonic clinical knowledge.

The invention provides an intraoperative real-time navigation system based on digital twinning, and relates to the technical field of digital twinning, and the system comprises a data collection module which is used for obtaining the three-dimensional form data of a liver and a biliary tract through an intraoperative ultrasonic imaging device, and collecting the elastic modulus distribution parameters of liver parenchyma and a bile duct wall; the construction registration module is used for constructing a real-time digital twin in the liver and gall area based on the three-dimensional form data and the elastic modulus distribution parameters, and carrying out multi-mode non-rigid registration on the digital twin and the liver surface topography and the vascular structure which are subjected to optical coherence tomography in the operation; therefore, a dynamic space mapping relation between the organ structure and the image data is established. According to the method, real-time navigation in the operation is realized through digital twinning, the obstacle avoidance path is updated, and the safety and efficiency in the operation are improved.

The invention discloses a liver point cloud registration method and device based on a Transform architecture, relates to the technical field of three-dimensional point cloud registration, and aims to solve the problems that mechanical characteristics of various liver tissues and geometric characteristics of point clouds are not comprehensively considered in the process of calculating rigid body and non-rigid body transformation in the existing registration technology, the difference between liver parenchyma and vasculature is ignored, and the registration accuracy is poor. And the registration effect is not good due to the interference of factors such as posture, gravity and pneumoperitoneum pressure. The method comprises the steps of obtaining a first point cloud and a second point cloud, preprocessing the first point cloud through a preset finite element analysis solver and a preset deformation condition to generate a third point cloud, and processing the first point cloud, the second point cloud and the third point cloud in combination with a liver point cloud registration model based on a Transform architecture to generate a liver point cloud registration result. According to the method, different modal features are fused by adopting a Transform architecture suitable for the point cloud, and the potential matching relationship among the modals can be captured, so that the registration effect is improved.

The invention relates to a TransUNet liver parenchyma image segmentation method based on an attention mechanism, and the method comprises the steps: introducing AxialAttention and a residual connection mode in TransUNet, solving a problem of information loss in skip connection through the method, better capturing a long-range dependence relation between positions in a liver parenchyma feature map, and improving the segmentation accuracy of the liver parenchyma image. The accuracy and expression ability of the liver parenchyma segmentation model are improved.

The application discloses a kind of intraoperative real-time navigation and force feedback system based on single-hole laparoscope, it is related to intelligent surgical navigation technical field, to solve the current in single-hole laparoscopic liver cancer resection, when liver parenchyma is disconnected, it is easy to damage intrahepatic vessel and cause active bleeding or diffuse bleeding, and the existing hemostasis method is difficult to consider effective hemostasis and avoid damage key structure, leading to the technical problem of high surgical risk, including multimodal perception module, intelligent processing and control module, augmented reality navigation module, and adaptive force feedback execution module.The application realizes the accurate distinction of diffuse bleeding of liver parenchyma and active bleeding of intrahepatic blood vessel by designing bleeding type adaptive determination algorithm based on multi-feature coupling, calculates the multi-dimensional characteristics such as hemoglobin concentration change rate, flow rate and uniformity by optical analysis of fluid perception unit in real time, and carries out intelligent identification by using adaptive determination algorithm trained by clinical data.

The application provides an intelligent grading method and system for diffuse liver lesions in ultrasound images, and belongs to the technical field of medical image processing.The method comprises the following steps: multi-dimensional quality evaluation and grading and shunt control of the ultrasound image; liver parenchyma segmentation and positioning of the region of interest; multi-scale parallel texture feature extraction and cross-scale attention fusion; quantitative ultrasound feature calculation and multi-source integration; synchronous output of fatty liver grading and liver fibrosis staging results by a double-task collaborative grading network, training loss containing ordinal consistency constraint to ensure medical rationality; and lesion heat map visualization and longitudinal monitoring trend analysis.The application realizes collaborative grading by utilizing the histological correlation of two lesions, and improves the diagnostic accuracy and objectivity.

This invention discloses a liver image recognition system and method based on graph neural networks, belonging to the field of medical image processing and intelligent recognition technology. It includes a liver image receiving module for receiving liver image data and performing slice processing, grayscale standardization, and spatial location information association processing on the liver image data to generate standardized liver image data. In this invention, by performing slice processing, grayscale standardization, and spatial location information association processing on the liver image data, a unified correspondence is formed between multiple liver image slices in three dimensions: slice number, grayscale expression, and spatial location. Results of liver parenchyma regions, candidate abnormal regions, and boundary transition regions are extracted. The adjacency relationships, grayscale variation relationships, and boundary continuity relationships of adjacent regions within the same slice are uniformly organized, thereby improving the data orderliness, regional discrimination ability, and completeness of the expression of relationships within a single slice of multi-slice liver images.

The present application relates to cell preparation process in the field of bioengineering, disclose a kind of high-efficiency preparation mouse primary hepatocyte method, comprising: perfusion needle is placed in reverse direction to liver direction through inferior vena cava, utilize the blood vessel clamp with elastic micro-tooth damping surface to lock the perfusion needle and inferior vena cava wall;The overflow damping of hepatic portal vein outflow end is dynamically regulated by blood vessel clamp, to construct controlled positive pressure permeation environment in liver vascular bed;Collagenase solution is radially permeated to liver parenchyma using the environment, the present application makes enzyme solution radial deflection and cross blood sinus barrier into di's cavity by constructing micro-pressure environment, eliminate the digestion dead zone originally due to flow path preference, ensure that enzyme molecule and extracellular matrix are uniformly contacted in global dimension, realize the collaborative promotion of tissue cutting efficiency and total amount of cell release, ensure that the output cell population has highly consistent physiological state.

This invention discloses a method for preparing a co-loaded dual-gene targeted delivery system and its application, involving the construction and preparation of a dual-gene (pHNF4α, pFOXA3) delivery system. This delivery system can target myofibroblasts (MFs) and activated hepatic stellate cells (aHSCs) and can be used for gene therapy of liver fibrosis. This invention synthesizes the targeting carrier material PEI. 25K -PEG 2K -pPB, through electrostatic adsorption, combines with pHNF4α and pFOXA3 to form a co-loaded dual-gene targeted delivery system, F4α / A3@PP-pPB. This delivery system, through the targeting group pPB, binds to MFs (metacellular matrix cells) that lead to excessive accumulation of extracellular matrix in fibrotic livers and to PDGFR (polydimethylformamide) highly expressed on the surface of aHSCs. On the one hand, it inhibits the activation of aHSCs; on the other hand, it transdifferentiates MFs into hepatocyte-like cells (iHep). These two modes, while combating liver fibrosis, can also achieve a certain degree of liver function reconstruction through transdifferentiated iHep cells, providing new ideas and methods for the effective treatment of liver fibrosis.

Problem: To provide an ultrasound diagnostic apparatus that allows a user to easily perform correction work on a data group. According to the solution, the invention discloses ultrasonic diagnosis equipment. The ultrasound diagnostic apparatus performs: selecting a first contrast image 2114 at a first staining time period T1, a second contrast image 211a at an early stage T2 after the staining time period T1, from among a plurality of contrast images acquired from a cross section containing a target of a subject to which a contrast agent has been administered, and a third contrast image 2212 at a later stage T3 after the early stage T2; calculating a difference [Delta] 1 between the average brightness of the target and the average brightness of the liver parenchyma in the contrast image 2114, a difference [Delta] 2 between the average brightness of the target and the average brightness of the liver parenchyma in the contrast image 211a, and a difference [Delta] 3 between the average brightness of the target and the average brightness of the liver parenchyma in the contrast image 2212; and if the differences [Delta] 1, [Delta] 2, and [Delta] 3 are all positive (or all negative), generating a WO image based on variations in the average brightness of the target over time to determine whether the contrast agent has been expelled from the target.

The present invention discloses a fully automatic ultrasound liver fat content detection method and system based on double Nakagami, comprising: S1. acquiring B-mode images of an ultrasound liver and IQ envelope data of an original RF signal; S2. performing image segmentation on the B-mode image using a deep learning segmentation method to segment out the liver parenchyma and vascular regions in the image; S3. post-processing the image segmentation results to obtain a candidate curved-edge trapezoidal ROI region containing only the liver parenchyma; S4. inputting the IQ envelope signal position area data corresponding to the candidate ROI region into a double Nakagami mixed distribution model, and estimating and optimizing the model parameters through an algorithm to obtain the fat content in the specified ROI region; the present invention realizes fully automatic quantitative detection of ultrasound liver fat content, which helps doctors or users complete the detection of liver fat content without relying on ultrasound clinical knowledge.

The invention discloses a construction method of an echinococcus alveolar mouse infection model, and belongs to the technical field of animal model construction. The construction method comprises the following steps: selecting a 6-8-week-old female mouse, anesthetizing, removing epidermal hair at the thoracic and abdominal positions, determining the position of the left leaf of the mouse liver under the guidance of an ultrasonic probe, and directly injecting the head segment of the alveolar echinococcosis with good activity into the liver parenchyma through auxiliary observation of the ultrasonic probe; the head section of the alveolar echinococcosis is extracted from gerbil mice infected with the alveolar echinococcosis. According to the ultrasonic-assisted modeling method disclosed by the invention, mechanical injury of liver tissue and nonspecific inflammation caused by invasive operation are avoided, noninvasive dynamic monitoring is realized, the success rate and survival rate of modeling are effectively improved, the operation time is shortened, meanwhile, injury to the liver and other visceral organs is reduced, and experimental errors are reduced.

This application discloses a method, apparatus, device, and medium for automatic liver scanning path planning. The method includes acquiring human body point cloud data, reconstructing the human body surface based on the point cloud data, determining the position information of the liver probe based on image data of the rib positions, and estimating the probe posture based on the position information and the human body surface to form a planned path for automatic liver scanning. This application first uses position planning to make the scanning path more reasonable, enabling the detection of not only liver parenchyma but also intrahepatic vascular diseases. Then, it uses pose planning to allow for a smaller angle when the probe adheres to the skin, improving ultrasound image quality.

The present invention discloses a liver point cloud registration method and device based on the Transformer architecture, which relates to the technical field of three-dimensional point cloud registration, and is used to solve the technical problem that the existing registration technology fails to comprehensively consider the mechanical properties of various liver tissues and the geometric properties of point clouds in the process of calculating rigid and non-rigid body transformations, ignores the differences in liver parenchyma and vascular system, and the interference of factors such as body posture, gravity, and pneumoperitoneum pressure, resulting in poor registration effect. The method includes obtaining a first point cloud and a second point cloud, pre-processing the first point cloud through a preset finite element analysis solver and preset deformation conditions to generate a third point cloud, and processing the first point cloud, the second point cloud, and the third point cloud in combination with a liver point cloud registration model based on the Transformer architecture to generate a liver point cloud registration result. The present invention adopts a point cloud Transformer architecture suitable for fusing different modal features, which can capture the potential matching relationship between each modality, thereby improving the registration effect.

The invention discloses a hepatic artery radiofrequency ablation method and ablation catheter. The ablation method comprises the steps that a target puncture point is positioned, and a radial artery puncture channel and an interventional ablation environment are established; guiding an ablation catheter to enter a target treatment point corresponding to the target artery branch; adjusting the end shape of the ablation section tube; the ablation catheter comprises an ablation section, a conveying section, a connecting section and a signal section. The catheter is inserted through a vascular intracavity path, penetrates into the hepatic artery or a near-end branch of the hepatic artery, targets autonomic nerves around the hepatic artery to carry out temperature control type radiofrequency ablation, and has the advantages of accurate positioning, safe control, uniformity of energy release and tissue adaptability; by adjusting the fitting posture of the spiral structure of the ablation section and adapting to the characteristic parameters such as the curvature direction, the tortuosity and the opening angle of the hepatic artery, it is ensured that the metal electrode can be effectively fitted with the tube wall to transmit radio frequency energy, meanwhile, the punching rate is reduced, liver parenchyma puncture injury is avoided, and meanwhile systemic intervention such as blood pressure regulation and metabolic function regulation is achieved.

The utility model discloses a hepatic parenchyma blood flow blocking and lifting device used in hepatic resection, which comprises a soft ring, one side of the soft ring is fixedly connected with an air bag, the outer side of the air bag is fixedly connected with an outer fixing soft ring, one side of the outer part of the air bag is fixedly connected with a first mounting seat, and the first mounting seat is fixedly connected with a second mounting seat. One side of the first mounting seat is fixedly connected with a second mounting seat, one end of the second mounting seat is fixedly connected with a third mounting seat, and one side of the third mounting seat is fixedly connected with a gas injection lifting belt. The air injection lifting belt comprises a focus, the tightness of the soft ring is adjusted by injecting air into the air bag through a medical injector, partial hepatic blood flow blocking is achieved, a surgical assistant can clamp the traction base of the air injection lifting belt through a common surgical operation instrument, multi-directional lifting traction is conducted on the liver, and the focus can be conveniently exposed.

The invention discloses a porta hepatis anatomy and hepatic parenchyma dissection identification method and system based on laparoscope video deep learning. On one hand, the porta hepatis anatomy and hepatic parenchyma dissection identification method based on laparoscope video deep learning comprises the following steps: collecting a recorded video stream data set; performing annotation processing on the video stream data set to obtain a preprocessed video stream data set; performing video clip segmentation and overlapping segment editing processing on the preprocessed video stream data set to obtain target video stream data; and a training operation step identification algorithm is adopted to carry out identification processing on the steps of porta hepatis anatomy and hepatic parenchyma dissection operation in the target video stream data, so that an operation step identification auxiliary result is obtained. On the other hand, the invention provides a porta hepatis anatomy and hepatic parenchyma dissection recognition system based on laparoscope video deep learning. The method has the advantage of being capable of assisting a clinician in formulating an operation scheme so as to reduce the complexity and risk degree of an operation.

The present invention relates to a covered stent for intrahepatic portal shunt capable of adaptively adjusting the length of the covering, comprising a tubular frame and a covering, wherein the covering comprises an upper self-curling segment of the covering, an intermediate fixed segment of the covering, and a lower self-curling segment of the covering which are connected in sequence, wherein the intermediate fixed segment of the covering is fixed on the tubular frame, and the upper self-curling segment of the covering and the lower self-curling segment of the covering are coated on the tubular frame, and the tubular frame is located below the covering to form a lower bare stent. After the covered stent of the present invention is placed, the covered stent is expanded by balloon dilation, and the self-curling segments of the covering at both ends naturally curl toward the middle, and stop curling when obstructed, so that the length of the covering is consistent with the liver parenchyma area, greatly reducing the adverse effects caused by the inconsistency between the covering length and the actual required length, and reducing the occurrence of complications.

This invention relates to a method, system, and storage medium for processing liver imaging data based on Gd-EOB-DTPA enhanced MRI. By acquiring multi-phase Gd-EOB-DTPA enhanced MRI image data and clinical laboratory data, the method standardizes and extracts regions of interest from the liver parenchyma and reference tissues, calculates and selects the optimal combination of MRI image parameters, and fuses these image parameters with blood biochemical indicators to construct a multimodal feature set. A model library is built using linear support vector machines, weighted K-nearest neighbors, and efficient logistic regression. Model training, validation, and testing are completed through stratified sampling and cross-validation to obtain a stable and reliable liver function grading assessment model, ultimately achieving intelligent, non-invasive, and quantitative assessment of ALBI grading. Compared with existing technologies, this invention has advantages such as being non-invasive, precise, standardized, interpretable, and easily clinically translated.

The application discloses a method for motion interaction of liver parenchyma and intrahepatic blood vessels and blood in a virtual surgery scene, mainly comprising: generation of a visual liver body model and an intrahepatic blood vessel body model; generation of a liver parenchyma body model; generation of a dense mesh of the intrahepatic blood vessel body model by means of a gmsh software, and generation of an intra-blood vessel blood model composed of a blood flow particle set; establishment of a liver parenchyma motion model based on PBD, and motion trends of the liver parenchyma and the intrahepatic blood vessels under the action of an external force, which are used to represent the motion of the liver parenchyma under the action of the external force, and the motion of the blood vessels and the blood particles caused by the deformation of the liver parenchyma, and simultaneously contain the flow of the blood particles under the condition of cutting; and realization of the motion constraints between the intrahepatic blood vessels and the liver parenchyma, and the motion constraint conditions of the blood flow in the blood vessels under the action of the external force in the virtual surgery scene. The method fully considers the motion characteristics of the liver and the blood vessels under the action of the force.

This invention provides a method, system, and device for constructing a 3D-printed liver model based on image data, comprising: acquiring CT and MRI image data of an individual patient; performing multimodal image segmentation on the CT and MRI image data to obtain structural segmentation images; fusing the structural segmentation images to obtain a liver and tumor anatomical structure model; performing three-dimensional reconstruction on the liver and tumor anatomical structure model to obtain a target three-dimensional visualization model; and 3D printing the target three-dimensional visualization model. This application integrates CT and MRI imaging modalities to obtain more comprehensive and accurate liver anatomical information. CT provides clear images of the liver parenchyma and blood vessels, while MRI provides more sensitive soft tissue contrast and tumor detection. The combination of the two can compensate for the shortcomings of a single imaging technology, improving the realism and information content of the model.

The present invention discloses a method for intelligent segmentation and recognition of liver CT images, comprising the following steps: S1. Using a liver segmentation model to segment the liver parenchyma region of an abdominal CT image to obtain a liver mask; S2. Multiplying the liver mask with the original input abdominal CT image to obtain a liver localization image; S3. Inputting the liver localization image into the liver segmentation model, which then performs Couinaud segmentation on the liver region. The present invention also discloses an intelligent segmentation and recognition model for liver CT images. The present invention can achieve more accurate liver segmentation recognition results.

Compositions and methods for delivering oleoylethanolamide (OEA) in a bioavailable formulation that reduces lipid accumulation in the liver of a subject. Described herein is a novel OEA formulation that allows the transport of the compound to the liver parenchyma, where this natural lipid amide exerts an anti-steatotic effect. This formulation has significantly higher oral bioavailability than either unformulated OEA or a different formulation of OEA (Levagen®-OEA). Furthermore, oral administration of the novel OEA formulation attenuates hepatic steatosis occurring in a mouse model of human metabolic syndrome. The composition is useful for treating human non-alcoholic hepatic steatosis.

The invention discloses a covered stent and a medical instrument assembly. The covered stent comprises a stent body, an outer-layer covering film and an inner-layer covering film. The stent is of a hollow structure and comprises a covered section and a bare section which are communicated with each other. The outer layer covering film is arranged in the circumferential direction of the outer side of the covering film section and extends in the axial direction of the covering film section. The inner-layer covering film is arranged in the circumferential direction of the inner side of the covering film section and extends in the axial direction of the covering film section; the end, close to the bare section, of the inner-layer covering film is connected with the end, close to the bare section, of the outer-layer covering film in a sealed mode, and an adjusting cavity with an opening is formed between the inner-layer covering film and the outer-layer covering film. And the ductility of the outer-layer covering film is smaller than that of the inner-layer covering film. By injecting and extracting a medium into and from the adjusting cavity, the inner-layer covering film can move under the influence of the pressure of the medium, and deformation of the outer-layer covering film is reduced. When the covered stent is applied to connection of portal veins and hepatic veins of the liver, in the deformation process of the inner-layer covering film, the outer-layer covering film can be basically unchanged, so that liver parenchyma can be protected to the maximum extent, and damage to the liver parenchyma is reduced.

The application discloses a kind of respiratory compensation method, device, equipment and storage medium, the method is decomposed into rigid displacement movement and non-rigid deformation movement for respiratory movement, and compensation and correction are carried out respectively for the characteristics of the two movements.For rigid movement, blood vessels are wrapped by liver parenchyma, and the rigid movement of blood vessels can be replaced by the liver. By tracking the centroid trajectory of the liver region in the X image sequence, the motion trajectory curve of the blood vessel can be quickly obtained, and the initial blood vessel road map is driven. Next, for the deformation correction of the blood vessel, the bending energy of the guide wire in the blood vessel lumen is calculated, and the structural features with higher energy are selected to drive the elastic registration of the image region at different times, and the non-rigid deformation compensation of the blood vessel is completed. The method can effectively and quickly track the surgical instrument in the blood vessel and reduce the dependence on contrast medium.

The invention discloses an HBV infected mouse model and a construction method and application thereof, and the construction method comprises the following steps: step 1, taking a healthy female HBV-Tg mouse with a positive HBV marker as a liver donor, taking out the liver through an operation, and cutting the liver into small blocks; step 2, taking a healthy female NPG mouse with severe combined immunodeficiency as a receptor animal, pulling the maximum leaf of the liver to the outside of the abdominal cavity through an operation, placing a liver tissue block of the HBV-Tg mouse on the exposed liver parenchyma surface of the NPG mouse, performing auxiliary fixation, then returning the liver back to the abdominal cavity, and then suturing; 3, the copy number of HBV DNA in NPG mouse serum is measured, and if the two continuous detection values are remarkably higher than the background value and the index can be continuously maintained at a certain level in the subsequent observation period, the HBV infected mouse model is successfully constructed. According to the invention, the process from donor sampling to receptor transplantation can be completed within several hours, and the model can be verified through serological detection 1-2 weeks after operation, so that the modeling period is greatly shortened.

The invention discloses a respiration compensation method, device and equipment and a storage medium, and the method decomposes respiration movement into rigid displacement movement and non-rigid deformation movement, and performs compensation and correction according to the characteristics of the two kinds of movement. For rigid motion, the blood vessel is wrapped by liver parenchyma, the rigid motion of the blood vessel can be replaced by the liver, the mass center track of the liver area in the X image sequence is tracked, a motion track curve of the blood vessel can be rapidly obtained, and an initial blood vessel path map is driven. Next, for the deformation correction of the blood vessel, calculating the bending energy of a guide wire in the lumen of the blood vessel, and screening out the structural characteristics of the part with higher energy, so as to drive the elastic registration of an image region at different moments, and complete the non-rigid deformation compensation of the blood vessel. The method can be used for effectively, quickly and continuously tracking the surgical instruments in the blood vessel and reducing the dependence on a contrast agent.

The application discloses a kind of cross-region MASH identification systems based on multi-frame ultrasonic image, it is related to image classification technical field, including: data acquisition module, for obtaining liver ultrasonic image and IQ envelope original data;Region identification module is used to extract maximum connected domain according to liver parenchyma mask chart, and determines the ROI region of each frame IQ envelope original data according to the maximum connected domain;Matrix generation module is used to divide grid to ROI region, calculate the shape parameter m of each grid corresponding Nakagami distribution, generate fat content distribution matrix;Fat weight generation module is used to input level weighting to each frame IQ envelope original data of ROI region using fat content distribution matrix, generate each frame weighted IQ signal;Classification identification module is used to extract features of multiple frames weighted IQ signal, input sequence modeling in Transform module, and carry out multi-classification identification based on sequence, obtain image recognition result.The application improves the capture ability of scattered lesions.

The invention discloses a flexible cushion block for exposing a liver parenchyma fracture surface, the flexible cushion block is suitable for being cushioned below the liver to lift the liver so as to expose the parenchyma fracture surface of the liver, the flexible cushion block is a flexible material piece, the flexible cushion block is generally in a triangular prism shape, the flexible cushion block is provided with an upper side edge and two lower side edges, and the upper side edge and the lower side edge are arranged on the upper side edge and the lower side edge respectively. An upper curved surface is formed at the upper side edge of the flexible cushion block, the middle part, in the length direction of the upper side edge, of the upper curved surface is sunken to the two ends, in the length direction of the upper side edge, of the upper curved surface, and a lower curved surface is formed between the two lower side edges; and the middle parts of the lower curved surfaces in the normal direction of the two lower side edges are concaved on the two sides of the normal direction of the two lower side edges. According to the embodiment of the invention, the flexible cushion block for exposing the liver parenchyma fracture surface can lift the liver to expose the fracture surface, and has the advantages of convenience in operation, convenience in operation, high reliability and the like.

The invention relates to the technical field of Mongolian medicines, discloses a Mongolian medicine composition for treating a liver-heat-type liver disease, and aims to solve the problems that when an existing Mongolian medicine scheme is used for treating complex diseases with liver parenchyma injury and liver and gall dysfunction, the synergism of liver heat clearing and liver and gall dysfunction is insufficient, and overall intervention is difficult. The Mongolian medicine composition is prepared from twenty-one medicinal materials including bunge corydalis herb, coptis chinensis, fructus gardeniae, bistort rhizome, bear gall powder, fructus choerospondiatis, radix aucklandiae, flos caryophyllata, amomum tsao-ko, myristica fragrans and the like. The traditional Chinese medicine composition is prepared by adopting a staged extraction process, comprehensively plays the effects of protecting the liver, lowering transaminase, benefiting the gallbladder, relieving jaundice and improving the gastrointestinal function, and shows better comprehensive treatment effect and safety on drug-induced, alcoholic and non-alcoholic fatty liver injuries.