The invention discloses a Lactobacillus plantarum M1-UVs29 with an accession number of CGMCC No.2591. The Lactobacillus plantarum M1-UVs29 can be isolated from fermented meat products of various resources, such as preserved ham, sausage, salami, Xuanwei ham and the like, and is obtained after induced mutation and optimization. The Lactobacillus plantarum M1-UVs29 is a new strain of the induced mutation and isolation and has superior safety and minimal toxic and side effects, and can relieve classical clinical symptoms of coronary heart diseases, atherosclerosis, hyperlipemia and the like and treat cardiovascular diseases of various coronary heart diseases, atherosclerosis, hyperlipemia and the like incurred by hyperlipemia in a safe and effective way. The Lactobacillus plantarum M1-UVs29 is applied to the production of beverages, and health products of dairy products, fermented milk, acidsoy milk and the like and food additives. The obtained products of beverages, health products and food additives, containing the fermented Lactobacillus plantarum M1-UVs29 or metabolins, cell debris or secretions thereof, can effectively degrade cholesterol self-cumulated by human bodies and self-contained by food.