4 results about "Mammalian tissue" patented technology

The disclosure provides an antimicrobial composition comprising hypohalous acid and a salt of an organic acid, as well as methods of use for disinfecting mammalian tissue, including wounds and burns, and other uses.

Aspect and embodiments relate to a tissue mimicking material, a clinical phantom including a tissue mimicking material and a method of manufacture of a tissue mimicking material. One aspect provides a tissue mimicking material comprising: an elastomeric solid foam. The foam comprises gas pockets dispersed in an elastomeric material matrix and a liquid lubricant arranged within the gas pockets of the elastomeric solid foam. Aspects and embodiments recognise that a self lubricating tissue mimicking material provides a mechanism to emulate particular in vivo mammalian tissues. The modified foam material in accordance with aspects has various physical properties and characteristics which can be tuned or refined to simulate the characteristics of a mammalian tissue which the foam is intended to mimic.

Optical, geometric, and / or physiological characteristics of a mammal and / or a pregnant mammal's abdomen may be used to determine a personalized calibration formula for the respective mammal or pregnant mammal's abdomen. This personalized calibration formula may be used to analyze or evaluate light transmission data corresponding to an optical signal that is detected by a photodetector and converted into the light transmission data to determine an oximetry value for the mammal, pregnant mammal, and / or fetus. The optical signal may be a composite of light that was incident on the mammal or pregnant mammal's abdomen her fetus. On some occasions, an image of the mammal's tissue and / or the pregnant mammal's abdomen may be received and used to generate a tissue model of the respective mammal's tissue or maternal abdomen. The tissue model may be used to generate, or adjust, the personalized calibration formula.

The present technology provides compounds as well as compositions including such compounds useful in targeted radiotherapy of cancer and / or mammalian tissue overexpressing prostate specific membrane antigen ("PSMA") where the compounds are represented by the following Formulas (I), or a pharmaceutically acceptable salt thereof (IA), or a pharmaceutically acceptable salt thereof (II), or a pharmaceutically acceptable salt thereof, wherein M1 is independently at each occurence an alpha-emitting radionuclide. Equivalents of such compounds are also disclosed.