137 results about "Edema" patented technology

The invention discloses a glioma radiotherapy postoperative risk assessment method based on a magnetic resonance image, particularly relates to the field of glioma radiotherapy patient health risk assessment, and is used for solving the problem that an existing assessment mode depends on manual interpretation and is difficult to predict bad clinical outcomes in advance. The method comprises the following steps: performing clinical data gridding reconstruction on a corticoid use cycle of a patient and tumor molecular typing, and combining morphological characteristics of an edema region in a magnetic resonance image to generate time-aligned clinical comprehensive characteristic vectors; mining a frequent association item set between the comprehensive feature vector and the pathological process to construct a mapping relation model; establishing a probability graph reasoning model of the bad outcome based on the pathological process vector sequence and the probability weight; and integrating the two types of models to form a causal reasoning network, and inputting a target patient feature vector to calculate an accumulated risk value of reaching a bad outcome. According to the method, an interpretable individual risk assessment result can be output, and a basis is provided for postoperative follow-up visit and intervention.

This disclosure relates to a catheter system that for precisely positioning fluid flow restrictors within a blood vessel. In particular, this disclosure provides a catheter system that includes a sheath with a first fluid flow restrictor mounted thereto, and a catheter that is slidably disposed within the sheath and has a second fluid flow restrictor mounted thereto. Inside a blood vessel, the sheath and the catheter are separately slidable, thereby allowing the first and second fluid flow restrictors to be positioned at precise locations within the blood vessel.

The invention discloses a central vein vascular access complication risk management method and related equipment. The method comprises the steps that based on basic physiological information and edema related information of a patient, ideal pressure values of different edema parts of the patient are determined through a treatment pressure decision model, and the treatment pressure decision model is obtained through training according to historical clinical treatment data; displaying the ideal pressure values of the different edema parts of the patient; in the binding process, the actual pressure value between the bandage and the skin of the patient is obtained, and the actual pressure value is displayed. The problems that in the prior art, complication supervision of a patient after a central venous catheter is implanted through a peripheral vein and infusion port implantation stays in static inquiry, the response speed is low, emergency situations cannot be recognized in time, the data collection mode is single, and the evaluation accuracy is insufficient can be solved.

The invention relates to the technical field of neurotrauma prognosis image analysis, and discloses a craniocerebral trauma prognosis prediction analysis system based on a three-dimensional model. According to the system, multi-scale segmentation and topology construction are carried out on a craniocerebral three-dimensional image of a patient, the morphological evolution rate of a trauma area is tracked, and key signal events in the trauma evolution process are accurately recognized in combination with an edema signal change curve. The system further quantitatively analyzes dynamic deviations associated with the integrity of normal brain tissue fiber bundles when a signal event occurs, thereby generating a lesion propagation path and mapping it to functional network nodes of a standard brain map, ultimately identifying a prognostic key brain network. According to the technical scheme, key event capture and path foresight prediction in the dynamic propagation process of the secondary injury after the craniocerebral trauma are realized, and the accuracy of prognosis evaluation is improved.

The invention discloses a human brain specific fluid flow direction identification method comprising the following steps: S1, multi-input network model construction: using a decoder to segment a task, and introducing a boundary detection task; high-density lesions and surrounding edema in the medical image are accurately segmented according to the Vi < T > and an attention mechanism; s2, fluid mechanics model construction and parameter setting, focus classification and risk quantification: optimizing time windows of two times of CT scanning; constructing a three-dimensional geometric model of high-density lesions, peripheral edema and normal brain tissue RO I; constructing initial physical field distribution; setting boundary conditions corresponding to a vascular rupture source and a focus drainage area; and dynamically adjusting the time step length based on the flow velocity and the diffusion coefficient. The invention provides a human brain specific fluid flow direction identification method, which combines image high-dimensional features with a multi-physics field coupling model, and reveals the heterogeneity of human brain specific fluid-blood conversion and contrast agent leakage in absorption and peripheral edema expansion modes.

The application discloses a self-help putting-on and taking-off device for pressure socks for obese patients with venous edema, which comprises a base, a lifting mechanism arranged on the upper end face of the base, an installation ring arranged on the working end of the lifting mechanism, a preloading support mechanism for bearing and rolling up the pressure socks movably arranged on the installation ring, a plurality of unrolling mechanisms for releasing the rolled-up pressure socks to the lower leg of a patient movably arranged on the inner side of the installation ring, and a control button arranged below the heel of the patient on the upper end face of the base. The device is simple in structure and reasonable in design, and a patient can easily complete the auxiliary operation of putting on the pressure socks alone, thereby reducing the dependence of the patient on the bending ability of the waist and abdomen, the gripping ability of the hands and the assistance degree of nursing personnel when putting on the pressure socks. Meanwhile, the control button is arranged below the heel, and the patient can complete the starting through the stepping mode, so that the operation mode is more in line with the actual use scene of the patient with inconvenient movement.

The LNTPI is a surgical instrument used to cut through fibrotic and edematous tissue to define the natural tissue plane of dissection. After defining the natural tissue plane, it is designed to move or carefully insinuate tissues along these natural planes without cutting the tissue, so that targeted organs or parts thereof could be viewed and reached during laparoscopic procedures. The following features make the LNTPI unique compared to standard blunt dissectors used in laparoscopy: 1. The tip of the LNTPI is coarse and not smooth. The tip has diagonal, spiral ridges from the sides which are carried onto the tip converging as a single spiral at the center of the tip, creating a pattern resembling that of a screw; 2. The ridges of the LNTPI are comprised of asymmetrical triangular ridges with an acute angle at the apex that may be leaning along with or against the rotation of the spiral; 3. The tip of the LNTPI is made of tungsten carbide metal instead of stainless steel; 4. Dissection can be done in the usual up, down, left, and right motions as standard dissectors; 5. The side of the LNTPI can be used to "peel" tissue by using the ridges on its side combined with a twisting movement. This maneuver cannot be performed using standard dissectors; and 6. The tip of the LNTPI can perform circumferential dissection when used with a twisting movement causing it to engage tissue like a "drill" along the natural tissue plane. The ridges that converge into a single spiral at the tip of the invention appear like a screw and with the proper twisting movement have a similar effect on tissue. Because of the texture, design, and material used for the tip of the LNTPI, it has the following advantages over standard dissectors: The LNTPI can engage tissues more easily even if the tissues are slippery due to the presence of blood or fluids. The LNTPI can be used to engage tissues through a twisting motion which motion allows the tissues to be engaged in a specific manner that defines natural tissue dissection planes. The LNTPI can insinuate / "peel" tissue by using the side spiral ridges in combination with a twisting movement. The LNTPI can perform circumferential dissection by using the tip and the convergence of the spiral ridges at the center of the tip in combination with a twisting movement. The transfer of lateral shear force to the tissue at various angles (45, 90, and 180 degrees) when using the LNTPI is significantly higher whether the motion is by a sweeping motion or twisting of the instrument, allowing it to insinuate better than standard instruments, especially in a wet field. Hand movements needed in insinuating tissue using the LNTPI are different from the usual hand movements when using standard dissection instruments. The hand movements in using LNTPI require less muscular effort and repetitiveness, thus preventing muscle fatigue and repetitive use injury among surgeons. The instrument is reusable, as compared to dissectors that have fabric at the tip, which must be disposed of and replaced once the fabric tip fully absorbs the blood or other fluid in the wet tissue surface.

This invention belongs to the technical field of monitoring methods, specifically disclosing a method for clinical monitoring of craniocerebral diseases based on electromagnetic field biodetection technology. The method includes preparing four electrode pads, which are respectively fixed to the left and right sides of the patient's brain, the forehead, and the occipital region. The electrode pads are then connected to a monitor. Based on the detection data from the four electrode pads, the monitor obtains detection parameters at each time point: R1 represents the perturbation coefficient generated by the left and forehead electrode pads, R2 represents the perturbation coefficient generated by the right and forehead electrode pads, R3 represents the perturbation coefficient generated by the left and occipital region electrode pads, R4 represents the perturbation coefficient generated by the right and left sides electrode pads and the occipital region electrode pads, and R5 represents the perturbation coefficient generated by the left and right sides electrode pads or the perturbation coefficient of the entire brain. The method assesses the degree of edema, the presence of hemorrhage, or fluid accumulation. Using four electrodes positioned at different locations in the brain allows for targeted, three-dimensional, multi-parameter detection of lesions in different parts of the brain.

The invention discloses an ancient moxibustion beauty method based on moxibustion therapy and facial acupoint stimulation and a matched device, relates to the technical field of traditional Chinese medicine beauty, and aims at improving facial complexion and conditioning skin through natural physical means. The device comprises a shell, a wooden plug cap, a vent hole, a stone needle base and the like, and a round hole and a stone needle tank opening are formed in the end face of the stone needle base to ensure uniform permeation of heat. The temperature is controlled by placing the moxa cones and adjusting the ventilation holes, and dynamic needle warming moxibustion stimulation is achieved by fitting face acupuncture points with the help of the curved surface design of the bottoms of the stone needles. The traditional Chinese medicine composition has the effects of promoting blood circulation, relieving edema, regulating qi and blood and relieving nerves, and finally, the problems of dull and loose skin color and the like are radically solved. Chemical stimulation is abandoned, far infrared rays are released through the natural stone needle material, the traditional Chinese medicine meridian theory is combined, beauty maintaining and young keeping from inside to outside are achieved, and safety, adaptability and long-term effect are achieved.

The invention belongs to the technical field of drug carriers, and particularly relates to a magnetic nano-drug carrier which is prepared by the following steps: selecting traditional Chinese medicine raw materials and auxiliary raw materials, and selecting corresponding equipment for treating the raw materials; traditional Chinese medicine raw materials are pretreated, effective components are extracted through ultrasonic and reflux combination, and finally an extracting solution is purified and concentrated; preparing through a coprecipitation method; the flexible traditional Chinese medicine dressing is prepared by taking anti-inflammatory, analgesic, blood-activating and blood-stasis-removing active ingredients of 19 traditional Chinese medicines as cores and combining with the local magnetic response enrichment characteristic of the magnetic nano-carrier, the flexible traditional Chinese medicine dressing is attached to a pressurized silica gel pad of a PCI postoperative wrist strap for use, local directional enrichment of the active ingredients of the traditional Chinese medicines in a wound is promoted through the magnetic carrier, and the wound healing effect is improved. The pressurizing silica gel pad has the synergistic effects of resisting inflammation, easing pain, improving microcirculation and dredging collaterals and restoring the pulse, solves clinical pain points such as inflammation edema, obvious pain and unsmooth local blood supply of a wrist puncture wound after the PCI operation, and meets the requirements of flexibility, ventilation and fitting of the pressurizing silica gel pad at the same time.

The utility model provides a scrotum support for a detumescence lymphatic pad of a male lymphedema patient, which relates to the technical field of medical tools and comprises a waistband, connecting bands and a support body, the connecting bands are connected to two sides of the front end of the waistband, and the support body is connected below the connecting bands; the support body is in a concave shape and comprises outer screen cloth and a lymph drainage pad, the lymph drainage pad is arranged on the inner side of the outer screen cloth, multiple sets of protruding particles are arranged and distributed on the inner side of the lymph drainage pad, and an adjusting piece is arranged on the outer side of the outer screen cloth; the waist support is tied on the waist through the waistband and connected with the support body through the connecting belt for limiting, the support body is prevented from falling off, the support body acts on the hypogastrium and scrotum lymphedema area of a male patient, and through the concave lymphatic drainage pad and the convex particles distributed in an arrayed mode, lymphatic backflow is promoted, and the problem of lymphadema fibrosis is solved. The product adapts to the structure requirement of male external genitalia, and the treatment quality is improved.

The invention relates to the field of treatment instruments, and discloses a pressure-adjustable breast cancer postoperative lymphedema wearable treatment device which comprises a tail end positioning mechanism located on a shoulder circumference sleeve frame, a second damping hydraulic part and an extending hinge frame are matched and used for fixing the forearm area of a patient, and the straight state of the arm is guaranteed; the pressing and limiting mechanism is located on the shoulder circumference sleeve frame and is matched with the big arm opposed frame, the double-helix screw and the limiting sleeve to form a multi-direction pressing structure for the big arm edema part of the patient; the pressing driving mechanism is located on the shoulder circumference sleeve frame and matched with a fixed shaft structure of the limiting sleeve, the oppositely-arranged parallel channels, the embedded ring frame and the inward-extending sliding frame. Through the independent air bag structure of the forearm ring sleeve and the attached arc plate, automatic inflation and deflation are achieved according to the perimeter of the limb, postoperative limb swelling changes are adapted, basic mechanical pressure is provided through radial movement of the inward-extending sliding frame, pressure distribution is finely adjusted through air bag filling, and compression blind areas are eliminated.

The invention discloses a traditional Chinese medicine composition, a plaster and a preparation method and application thereof. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 25-60 parts of fennel, 25-60 parts of semen plantaginis, 25-60 parts of fried semen raphani, 50-150 parts of fried lindera aggregata and 50-150 parts of piper cubeba. The prepared traditional Chinese medicine composition, namely the combined spicebush root-siza powder, can improve complications such as postoperative urinary retention, abdominal distension, anal pendant expansion, wound pain, hemafecia, seepage and edema of a patient, can promote postoperative wound healing, effectively shortens the hospitalization days, and fundamentally solves the problems of surgical pain and difficult healing of the patient.

The invention relates to the technical field of arthritis treatment jackets, in particular to a rheumatoid arthritis hand auxiliary treatment jacket which comprises a glove, the glove is divided into a palm face and a hand back face, a wrist is constructed on one side of the glove, and a pressure control piece is arranged on the glove; the pressure control part comprises a cavity constructed in the glove, the cavity divides the glove into an outer layer and an inner layer, the outer layer is made of a heat preservation material, and the inner layer is made of an elastic material; a water injection valve communicated with the cavity is arranged on the glove, and liquid is allowed to enter and exit from the cavity by opening and closing the water injection valve; the three pressure control modes of wrist air bag pressurization and hand movement dynamic pressurization are adjusted through the liquid medicine injection amount, a patient can autonomously select pressure gears according to the illness state and the scene, low-gear mild pressurization is conducted during daily office mild movement, slight aching pain is relieved, operation is not affected, middle-gear moderate pressurization is conducted when joint swelling pain is aggravated, and therefore the patient can feel more comfortable. During night rest, middle and low gears can be flexibly selected, and morning stiffness is relieved while constraint feeling is avoided.

The present application belongs to the technical field of medical devices, and relates to medical consumables for treating spinal cord injury, in particular to a double-layer core-shell structure artificial fiber dura mater for spinal cord injury and a preparation method thereof. The double-layer core-shell structure artificial fiber is used to form a film structure, the double-layer core-shell structure artificial fiber is composed of an outer shell structure and an inner core structure, the material of the outer shell structure is composed of PLGA and PEG, the outer shell structure is loaded with NM, the material of the inner core structure is PLA, and the inner core structure is loaded with NT3. The double-layer core-shell structure artificial fiber dura mater provided by the present application has the advantages of reducing spinal cord edema, preventing fiber adhesion, improving the microenvironment, promoting the repair of spinal cord injury, and the like.

An apparatus for treating or preventing venous deficiency, thrombus development, orthostatic intolerance, lymphedema, and / or edema comprising a sleeve wearable on a limb of a user; an upper bracket and a lower bracket releasably couplable to the limb; an actuator coupled to one of the upper or lower brackets; a shaft coupled to the actuator and the other of the upper or lower brackets; a plurality of cams fixedly coupled to, and longitudinally spaced along, the shaft; and a respective plurality of flexible elements each coupled to one of the plurality of cams and to the sleeve. Rotational motion of the actuator about an axis of rotation causes the plurality of cams, via the respective plurality of flexible elements, to induce a peristaltic pressure wave in the limb.

Apparatuses and methods for preventing the onset and / or progression of bowel edema during abdominal surgery and / or post-operative ileus are provided. The disclosed apparatuses comprise a structure for retracting the bowel during abdominal surgery and a means of applying negative pressure therapy to the bowel during abdominal surgery. Retracting the bowel provides unobstructed access to other regions of the abdominal cavity for the surgeon and the use of negative pressure therapy prevents the onset or progression of edema and / or ileus. Methods of preventing the onset or progression of edema and / or ileus are provided, comprising the deployment of the disclosed apparatuses and the application of negative pressure therapy.

The utility model provides a multifunctional lifting pad for preventing pressure sores and foot drop, which belongs to the field of medical equipment, and comprises an L-shaped lifting pad support, the lifting pad support comprises a lower limb supporting part and a foot supporting part, the lower limb supporting part is connected with the foot supporting part, the front side of the lower limb supporting part is provided with an arc slope, and the arc slope is connected with the lower limb supporting part. A lower limb fixing groove is formed in the lower limb supporting part, a foot fixing groove is formed in the foot supporting part, a heel groove is formed between the lower limb fixing groove and the foot fixing groove, the depth of the heel groove is larger than that of the lower limb fixing groove, and a sole covering sleeve is arranged at one end of the foot fixing groove. According to the lifting pad, the lifting pad support is arranged to be in the L shape, foot drop can be prevented, the lifting pad support is made of polymer gel, pressure sores of lower limbs can be prevented, and meanwhile the lower limbs are lifted to reduce edema.

The utility model discloses a restraint device for preventing skin injury of a patient, which comprises a first fitting glove and a second fitting glove arranged under the first fitting glove, adjusting mechanisms are uniformly distributed on the outer side edges of the first fitting glove and the second fitting glove, and limiting mechanisms are arranged on the first fitting glove and the second fitting glove. According to the restraining device for preventing the skin of the patient from being injured, the first hook-and-loop fasteners can be folded upwards to be bonded with the corresponding second hook-and-loop fasteners, and the distance between the first attaching glove and the second attaching glove can be adjusted according to the hand of the patient; the first fitting glove and the second fitting glove are kept in compression contact with the fifth hand skin surface of the patient, the multiple sets of first hook-and-loop fasteners and the multiple sets of second hook-and-loop fasteners are matched so far, fixation is firmer, meanwhile, the hand of the patient cannot be tightened, the skin of the patient is more comfortable after long-time use, and the skin edema condition cannot be caused.

The invention relates to the technical field of medical instruments, in particular to a nasal cavity insertion type trachea cannula examination and administration device which comprises a flexible outer tube, when the nasal cavity insertion type trachea cannula examination and administration device is used, one end of the outer tube is inserted into the throat position from the nasal cavity of a patient, and the other end of the outer tube is located outside the patient and electrically connected with control equipment; the observation head is arranged at one end, extending into the body of the patient, of the outer tube and is electrically connected with the control equipment; the dosing tube is arranged along the outer tube, one end of the dosing tube is fixedly connected and communicated with a liquid ring, the liquid ring is arranged at one end, close to the observation head, of the outer tube and fixedly connected with the inner wall of the outer tube in an attached mode, and liquid medicine is atomized through the liquid ring and sprayed to the throat edema position. According to the device, upper respiratory tract edema examination, administration treatment and trachea cannula and trachea gap detection can be achieved at the same time, the problems that upper respiratory tract edema examination is inconvenient, administration is not timely, and trachea cannula and trachea gap detection is lacked are solved, the operation process is simplified, the workload of medical staff is reduced, and the rehabilitation speed of a patient is increased.

The utility model discloses a kind of wearable undershirt type abdominal belt after axillary lymph node dissection, including abdominal belt main body and reinforcing belt, abdominal belt main body is the undershirt body with suspender body, one end of reinforcing belt is passed from one side axillary after with other end detachable connection in the upper arm of other side near shoulder, reinforcing belt is rotated in the outer circumferential side of abdominal belt main body.The utility model is convenient to wear, and dressing process is convenient, can reduce the burden of medical staff, ensure the comfort and functionality of patient in wearing process, facilitate patient to carry out postoperative limb function exercise;External adjustable reinforcing belt can better reasonably and accurately fix position, increase effective pressurizing effect, can accurately carry out part pressurizing by adjusting position, effectively reduce the effect of ideal caused by abdominal belt slackening or inaccurate pressurizing position;Adopt non full package structure, easy to observe patient bleeding and effusion and limb edema condition, be favorable to medical staff to the state of patient in rehabilitation process carries out real-time monitoring and adjustment.

The invention discloses a neurotumor postoperative rehabilitation nursing device, which comprises an elastic net cap, an elastic net cap, a main body frame assembly, an elastic net cap, a rehabilitation nursing device, a rehabilitation nursing device and a rehabilitation nursing device, the elastic net cap is provided with air holes, and the main body frame assembly is arranged below the elastic net cap; a limiting rod is slidably arranged on the main body frame assembly, one end of the limiting rod is fixedly connected with a push plate, and the front surface of the push plate is fixedly connected with a supporting soft cushion; by means of the components, the driving sleeves are rotated to be connected with the winding sleeves, the frame can be contracted and expanded to be matched with the head shape and edema changes, the threaded sleeves are connected, pressure can be adjusted in a partitioned mode (pressurization of an edema area and pressure reduction of a wound area), the device does not need to be replaced, and the wound problem is avoided; the U-turn surrounding / pressure regulating function shares the driving sleeve, operation can be conducted only by rotating the sleeve, extra parts are not needed, the device is suitable for patients and medical care, and errors are avoided.

The utility model discloses an adjustable exercise rehabilitation soft brace which comprises a soft brace body, a supporting soft plate is arranged on one side of the soft brace body, air holes are evenly distributed in the supporting soft plate, bandages are evenly distributed on the supporting soft plate, an adjusting mechanism is arranged in the center of one side of the supporting soft plate, and the adjusting mechanism is arranged on the other side of the supporting soft plate. A neck support is arranged above the adjusting mechanism, the dismounting and mounting mechanism is arranged at the top of the adjusting mechanism, and the bottom end of the neck support is connected with the dismounting and mounting mechanism through a mounting piece. By installing the soft brace body, the binding band, the supporting soft plate, the adjusting mechanism, the neck support, the shell, the lifting sleeve, the micro motor and the lead screw, the soft brace body is worn through the binding band, the neck of a patient is supported on the neck support, the neck support is lifted and supported, and then the cervical vertebra of the patient is pulled and fixed; and the traction degree can be automatically adjusted, so that the cervical traction device is more flexible to use.

The invention provides a lower limb lymphedema rehabilitation training device which comprises a supporting plate, a first rotating plate is rotatably installed on one side of the supporting plate, a second rotating plate is rotatably installed on the side, away from the supporting plate, of the first rotating plate, and protection assemblies are arranged on the side face of the first rotating plate and the side face of the second rotating plate. A training assembly with adjustable resistance is arranged between the first rotating plate and the supporting plate, and an elastic positioning assembly is arranged between the first rotating plate and the second rotating plate. The lower limb lymphedema rehabilitation training device is used for lower limb training when a patient lies in bed, lymph backflow is assisted by raising legs, rehabilitation treatment of the lower limb lymphedema patient is facilitated, medical staff can adjust the strength of the training device according to the physical quality of the patient in the training process, and the lower limb lymphedema rehabilitation training device is suitable for being used by different staff; meanwhile, the training device can be used for massaging the shanks of the patient, dredging channels and promoting lymph backflow, has ventilation and perspiration functions and is convenient for the patient to use.

The utility model discloses a novel circumcision anastomat which comprises an inner ring and an outer ring, the inner ring is used for supporting the inner side of a prepuce, the outer ring is composed of a pair of outer ring lock catches which can be mutually locked, a dull knife is arranged on the inner side of each outer ring lock catch, a drainage assembly is arranged on each dull knife, and the outer ring lock catches are buckled on the outer side of the inner ring. The blunt knife extrudes the foreskin tissue on the outer side of the inner ring, the to-be-cut tissue and the reserved tissue are isolated through the arranged inner ring and the locking mechanism, so that the to-be-cut tissue necroses and falls off, then cutting is completed, in addition, tissue fluid is guided out to be away from the isolation belt through the drainage assembly, and it is guaranteed that the position nearby the tissue fluid is kept dry; lymph accumulation and flowing around are avoided, and cross infection is reduced, so that edema is relieved, and healing is faster.

Disclosed herein, in part, is a method for administering a liquid pharmaceutical formulation containing a loop diuretic to a patient via subcutaneous injection. Methods for treating conditions such as fluid overload, congestion, edema, and hypertension in a patient in need thereof are also provided.

This invention relates to the field of leg and foot elevation pad technology and discloses a leg and foot elevation pad, including a base plate and a support plate located above the base plate. The top surface of the support plate is recessed to form a leg support groove, and an inner cavity is formed inside the support plate. A sliding cabinet is slidably installed in the inner cavity along the length direction of the support plate. Side rods are movably and retractably provided at both ends of the sliding cabinet. The ends of the side rods are connected to the insertion rods through connecting rods. A floating side pressure plate is provided at the close ends of the two insertion rods. This leg and foot elevation pad, by setting a side pressure plate structure in the leg support groove that can be linked to changes in lateral edema of the lower leg, and connecting the displacement of the side pressure plate to a lifting adjuster, enables the device to automatically drive the support plate to rise based on changes in the degree of edema in the lower leg of patients with heart failure, thereby achieving adaptive elevation in response to changes in edema in patients with heart failure without the need for frequent manual adjustments by nursing staff.

A method and formulations are developed for enhancing solubility and improving the permeability of bumetanide across a mucosal membrane. The formulation includes bumetanide in various water-cosolvent mixtures, which include at least one of an alcohol, polyether, glyceride, pyrrolidone, or any combination thereof. In some embodiments, the formulation has a pH of about 3.5 to about 8.0. In some embodiments, the formulation enhances the solubility and permeability of the bumetanide. Also disclosed is a use of the formulation for rapidly achieving effective bumetanide plasma concentration leading to diuresis. In some embodiments, the formulation can be administered to a subject conveniently without injection in the treatment of edema associated with heart failure or other conditions.

The utility model relates to a block-up device for preventing edema after internal arteriovenous fistula forming, which is characterized by comprising a base, a support component, a cushion block, a control panel, an adjusting component, a locking component, rollers and the like, the support component is rotatably connected onto the base and is in contact with a patient, the rollers are rotatably connected to the bottom of the support component, the cushion block is connected to the rear side of the base, and the control panel is arranged on the control panel. A control panel is installed on the left side of the base, an adjusting assembly used for adjusting the height of the supporting assembly is arranged in the base and is in extrusion fit with the rollers, and a locking assembly used for limiting rotation of the supporting assembly is arranged on the side edge of the base. The device has the advantages that through the cooperation of the motor, the lead screw and the wedge-shaped push block, medical staff can flexibly adjust the inclination angle of the supporting assembly according to the specific requirements of the surgical site of a patient, the purpose of adjusting the angle of the supporting assembly is achieved, and more fit and comfortable support is provided for the arm of the patient.