472 results about "Circulatory system" patented technology

Set forth are vascular valves and servovalves and methods of using the same that may be positioned in the circulatory system without interrupting blood flow to facilitate solid organ transplantation so as to reduce graft organ anoxia and degradation before and after harvesting and storage, thereby minimizing late-term cardiac allograft vasculopathy as a major cause of graft failure. Along the urinary tract, bypassing bladder-generated urge sensation by diverting urine directly from the ureters to a neobladder or collection bag alleviates intractable incontinence, nocturia, urethral syndrome, overactive bladder, dysuria, or frequency. Where the lower tract is missing, a prosthesis can thwart disease and preclude the degenerative metaplastic transition to carcinoma risked when gut is used to construct a conduit for urine, a neobladder, and / or high-maintenance stoma. Druglines to valves and servovalves can directly pipeline-target medication to nidi, anastomoses, or any other trouble spots.

The present invention relates generally to improved systems and methods for removing undesirable material residing in vessels. More specifically, the present invention relates to systems and methods for using at least one cannula to remove substantially en bloc, from a site of obstruction or interest, undesirable material without fragmentation and without excessive fluid loss.

The invention relates to the technical field of data monitoring and analysis, and discloses a hemodialysis care unit extracorporeal circulator monitoring method and system and a storage medium. The method comprises the steps that vital signs and identity features of a patient are collected, a sign feature data set is obtained through fusion processing, and initial dialysis parameters are generated; analyzing the sign feature data set to obtain blood vessel state parameters; adjusting a circulation system based on the blood vessel state parameters and the initial dialysis parameters to obtain circulation control data; monitoring a dialysate path by using the circulation control data, and generating a liquid path operation parameter; the circulation control data and the liquid path operation parameters are integrated to analyze the system state, and equipment early warning indexes are formed; and evaluating equipment operation according to the early warning index and generating an automatic control instruction. According to the method, deep integration of the physical sign characteristic data of the patient and the equipment operation data is realized, a data-driven objective decision basis is provided for the dialysis process, and the safety and effectiveness of dialysis treatment are improved.

The invention relates to the technical field of health management of old people, and discloses a method and a system for predicting multiple diseases of old people. The method comprises the following steps: acquiring multi-modal health monitoring data of a target old person in a preset time period, wherein the multi-modal health monitoring data comprises physiological index time sequence data, a medication record sequence and a daily activity ability evaluation result; and performing cross-modal correlation analysis on the multi-modal health monitoring data to generate a disease interaction characteristic matrix containing metabolic disease correlation degree, circulatory system disease coordination index and neurodegenerative disease progress rate. And performing hierarchical clustering processing on the feature matrix by adopting a dynamic weight distribution algorithm, and outputting potential common disease combinations of the target old people and a priority score of each common disease combination. And generating a personalized intervention strategy set including a drug interaction avoidance scheme, a rehabilitation training intensity adjustment scheme and a nutrition intake ratio scheme according to the priority score.

A method for capturing dislodged vegetative growth during a surgical procedure is provided. The method includes maneuvering, into a circulatory system, a first cannula having a distal end and an opposing proximal end, such that the first cannula is positioned to capture the vegetative growth en bloc. A second cannula is positioned in fluid communication with the first cannula, such that a distal end of the second cannula is situated in spaced relation to the distal end of the first cannula. A suction force is provided through the distal end of the first cannula so as to capture the vegetative growth. Fluid removed by the suction force is reinfused through the distal end of the second cannula. Subsequent to becoming dislodged, the vegetative growth is captured by the first cannula. A method for capturing a vegetative growth during removal of a pacemaker lead is also provided.

The invention provides a damp heat-oxygen-internal pressure-load coupled non-metal pipeline aging device and a method capable of evaluating the service life of an in-service non-metal pipeline. The non-metal pipeline aging device comprises six parts, namely an inner cavity, a box body temperature control system, a box body humidity control system, a pipeline internal pressure control system, a pipeline external load loading device and an air supply circulating system, and an accelerated aging test of a non-metal pipeline under different working condition combinations of four factors, namely damp heat, oxygen, internal pressure and load can be carried out by virtue of the aging device. Measuring oxidation induction periods before and after aging of the in-service non-metal pipeline and the non-metal pipeline with the same mark through a differential heat scanning method, substituting the oxidation induction periods into a non-metal pipeline aging life prediction formula coupled with damp heat-oxygen-internal pressure-load factors, and calculating to obtain the service aging life. According to the method, damp heat-oxygen-internal pressure-external load multi-factor coupling is realized, so that an actual service environment is accurately simulated, and comprehensive technical support can be provided for safe operation of the non-metal pipeline.

The present invention relates generally to improved systems and methods for removing undesirable material residing in vessels. More specifically, the present invention relates to systems and methods for using at least one cannula to remove substantially en bloc, from a site of obstruction or interest, undesirable material without fragmentation and without excessive fluid loss.

A method for optimizing a flow of water of a swimming pool or spa includes monitoring a parameter associated with performance of a first piece of equipment of the swimming pool or spa, such as but not limited to a heat pump, and relative to a target for the parameter. The method includes activating a bypass valve such that water bypasses the first piece equipment based on the parameter reaching or exceeding the target. The method includes controlling operation of a second piece of equipment of a circulation system responsive to activation of the bypass valve.

The invention regards an adhesive patch for oscillatory blood pressure measurements of a subject, the patch comprising: an actuator arranged for application of an external pressure onto a target part of the circulatory system of the subject; a pressure sensor arranged in connection with the actuator, wherein the pressure sensor is adapted to measure the external pressure; wherein the patch is arranged to obtain oscillatory blood pressure measurements of the target part by setting the external pressure applied to the target part above a systolic blood pressure, and thereafter gradually releasing the external pressure until it is below a diastolic blood pressure, while measuring, by the pressure sensor, resulting pressure oscillations of the actuator.

The invention discloses a pulsating pump system, a medical device implantation intervention simulation system and a control method, and relates to the technical field of medical device tests.The pulsating pump system comprises a ventricular simulation cavity, a ventricular intervention simulation cavity, a ventricular intervention simulation cavity, a ventricular intervention simulation cavity, a ventricular intervention simulation cavity and a ventricular intervention simulation cavity, a liquid inlet and a liquid outlet of the ventricular simulation cavity are respectively connected with a liquid inlet pipe and a liquid outlet pipe through one-way valves; the driving assembly is relatively and fixedly connected with the ventricular simulation cavity and is used for driving the diaphragm to do regular reciprocating motion; the flow sensor is connected to the liquid outlet pipe in series and used for detecting the flow velocity of the liquid medium of the circulating system; the pressure sensor is connected to the liquid outlet pipe in series and used for detecting the pressure of liquid at the designated position of the circulating system; according to the pulsating pump system, the medical instrument implantation intervention simulation system and the control method, the physiological waveform in the blood vessel of the human body can be accurately reproduced through closed-loop control.

The invention discloses an extracorporeal circulation system and a control method thereof, and relates to the technical field of medical instruments. The extracorporeal circulation system comprises a membrane oxygenator, a microembolus filter, a rolling pump, a first pressure detector and a second pressure detector; a liquid inlet of the membrane oxygenator is communicated with the arterial cannula; the microembolus filter is circularly communicated with the membrane oxygenator, and the liquid outlet end of the microembolus filter is communicated with the venous cannula; the rolling pump is circularly communicated with the membrane oxygenator; the first pressure detector is communicated with the rolling pump and is used for detecting the outlet liquid pressure of the rolling pump and generating a first pressure signal; the second pressure detector is communicated with the microplug filter and is used for detecting the inlet liquid pressure of the microplug filter and generating a second pressure signal; the structure of the extracorporeal circulation system and the control method of the extracorporeal circulation system are improved, the accuracy and timeliness of medical staff for judging the oxygenation effect of the membrane type oxygenator are improved, the membrane type oxygenator can be replaced in time, a large number of complications can be avoided, and the death rate of patients is reduced.

The utility model relates to an air fryer with a good heat dissipation effect, which comprises a machine body, a cooking cavity arranged in the machine body and a hot air circulation system communicated with the cooking cavity, the machine body is provided with a mounting groove, a box body with liquid storage cavities is detachably arranged in the mounting groove, and the liquid storage cavities comprise a first liquid storage cavity and a second liquid storage cavity; a mounting cavity is formed in the machine body, a liquid conveying system is arranged in the mounting cavity, and the liquid conveying system comprises a first pump and a second pump which are communicated with the first liquid storage cavity and the second liquid storage cavity respectively; a heat dissipation air channel communicated with the installation cavity is arranged in the machine body, a heat dissipation assembly is arranged in the heat dissipation air channel, and a first ventilation opening and a second ventilation opening which are communicated with the installation cavity and the atmosphere are formed in the positions, close to the first pump and the second pump, of the machine body respectively. Through the first ventilation opening and the second ventilation opening, heat dissipation of the first pump and the second pump can be achieved through external cold air, and the heat dissipation effect is effectively improved.

The disclosure relates to devices and methods for the treatment of edema, which devices use a restrictor for flow compensation. Devices and methods of the invention further use a flow-restrictor in the circulatory system, upstream of an intravascular pump, to balance pressure changes induced by the pump and to compensate for downstream flow. The device may be provided as an indwelling, intravascular catheter with a mechanical pump such as an impeller and a selectively deployable restrictor such as an inflatable balloon. Congestive heart failure or edema is treated by\operating the pump in an innominate vein and using the restrictor for flow compensation, to restrict the upstream flow and thus amplify or maintain pressure reduction at the lymphatic outlet.

The invention relates to the technical field of data analysis, can be applied to business system platforms of financial science and technology, medical treatment and health and the like, and discloses a human body state characteristic value analysis method, device and equipment and a medium. Performing system state analysis on an endocrine system, a circulatory system and a respiratory system of the user according to the physical examination data to obtain a system state characteristic value set, constructing a physiological index vector and a disease course characteristic vector according to the physical examination data, and constructing a complication incidence matrix according to case data; performing complication association analysis on the user according to the physiological index vector, the disease course feature vector and the complication association matrix to obtain a complication feature value, analyzing a criticality feature value of the user according to a system state feature value set and the complication feature value to obtain a hazard feature value set, and performing weighted summation on the hazard feature value set to obtain a complication feature value set; and obtaining a human body state characteristic value. And the accuracy of human body state characteristic value analysis is improved.

The invention relates to the technical field of biomedical engineering, in particular to a separated type organ-like chip model and a use method thereof.The model comprises a chip, an organ-like unit module and a fluid control system, and the use method comprises the steps that firstly, the chip is assembled and prepared; step 2, cell inoculation and culture; step 3, establishing and operating a fluid circulation system; step 4, organ-like unit function detection and data acquisition; 5, analyzing an experimental result and adjusting the model; the model is connected with a micro-fluidic channel through an independent cavity, and the characteristics, cell types and culture conditions of a cell culture bracket can be regulated and controlled according to the characteristics of simulated organs. Meanwhile, the micro-fluidic channel ensures stable and ordered material exchange among the organoid units, and is beneficial to more accurately screening out effective treatment schemes and drug targets.

The present invention relates generally to improved systems and methods for removing undesirable material residing in vessels. More specifically, the present invention relates to systems and methods for using at least one cannula to remove substantially en bloc, from a site of obstruction or interest, undesirable material without fragmentation and without excessive fluid loss.

Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

The invention discloses a disposable isolated organ continuous oxygenation mechanical perfusion circulation system and a working method. A circulation pipeline of the circulation system is provided with a to-be-carried oxygen conveying pipeline and an oxygen-carrying perfusion pipeline; the output end of the organ low-temperature storage container is connected to the to-be-carried oxygen conveying pipeline, and the pump pipe and the oxygenator are arranged on the to-be-carried oxygen conveying pipeline; the organ transfer sleeve assembly is detachably mounted on the organ tray assembly; the organ tray assembly is arranged in a cavity of the organ low-temperature storage container; the output end of the oxygenator is connected to the oxygen-carrying perfusion pipeline, the automatic bubble separator installed on the oxygen-carrying perfusion pipeline is connected to the input end of the organ transfer sleeve assembly, and the pressure sensor is installed on the oxygen-carrying perfusion pipeline. The device has the following advantages: the device has an automatic bubble removal function; on the basis of a low-temperature mechanical perfusion function, the oxygenation function is achieved; light weight is taken into account, and portable transfer of perfusion equipment is facilitated; the method has higher safety and reliability.

The invention belongs to the technical field of medical instrument experiments, and particularly relates to a ventricle simulator and an in-vitro blood circulation simulation device simulating cardiac pulsation. The ventricular simulator comprises a ventricular cavity, a ventricular simulator body, a ventricular simulator body and a ventricular simulator body, the bionic ventricle is hollow, openings are formed in the two transverse ends of the bionic ventricle, the bionic ventricle can be contracted or relaxed and is transversely arranged in the ventricle cavity, and the two ends of the bionic ventricle and the two ends of the ventricle cavity are sealed and fixed through a front connecting cover and a rear connecting cover, so that the interior of the bionic ventricle is separated from the ventricle cavity; the front connecting cover and the rear connecting cover are each provided with a transverse communicating opening communicating with the interior of the bionic ventricle. The ventricle simulator innovatively realizes complete isolation of an internal circulation system and an external driving system, reduces external interference and pollution, and ensures stable operation.

The invention relates to the technical field of human body blood gas monitoring, and discloses a blood gas monitoring method and system of an extracorporeal circulation system.The method comprises the steps that current blood gas data of a patient is collected, cleaning is conducted, blood gas features are extracted, the features are input into a blood gas prediction model, and the change trend of the blood gas data of the patient in the future effective intervention period is predicted; if it is monitored that the blood gas data of the patient tends to be bad in the time period, parameters of the oxygenator are actively adjusted; meanwhile, according to the basic information of the patient and the current blood gas data, a corresponding oxygenation parameter adjustment strategy is screened, the change trend of the blood gas data of the patient is continuously predicted, and whether the oxygenation parameter adjustment strategy is replaced or not is judged according to the updated prediction result until the predicted blood gas data of the patient is in a good change trend; the technical problem that existing blood gas monitoring lacks effective early warning is solved.

The invention discloses an indoor ventilation and air purification circulation system for an operating room. The indoor ventilation and air purification circulation system comprises S1, a fresh air introduction module; s2, a primary filtering module; s3, a secondary filtering module; s4, a terminal filtering module; s5, a disinfection module; s6, checking the module; s7, an air supply module; s8, an air outlet module; s9, a discharging module; the S1 fresh air introduction module comprises a fresh air inlet, an electric air valve arranged in the fresh air inlet, and a rainproof shutter and an insect-proof net which are arranged on the outer side of the fresh air inlet, and the S1 fresh air introduction module is responsible for introducing fresh air from the outside and providing sufficient fresh air for the operating room; through a multi-stage composite filtering structure and an advanced sterilization technology, various pollutants in air can be effectively removed, the air quality of an operating room is remarkably improved, the operation infection risk is reduced, meanwhile, a unique airflow organization design is adopted, ventilation dead corners are eliminated, sufficient circulation of indoor air is guaranteed, and a stable air environment is provided for an operation.

The invention relates to the technical field of biological medicine, in particular to construction and application of a candida patient death risk prediction model. The model is based on traditional SOFA scoring, core variables are screened through single-factor and multi-factor logistic analysis and LASSO regression analysis, respiratory system, blood coagulation function and circulatory system SOFA scoring and key indexes such as the maximum lactic acid value, the minimum albumin value and the maximum blood urea nitrogen (BUN) are integrated, and a prediction model is constructed through logistic regression. Through multi-center data verification, the AUC of an internal verification queue reaches 0.826, the AUC of an external verification queue is 0.813, and a calibration curve shows that the predicted death rate is highly consistent with the actual death rate. Patients can be divided into a high risk group and a low risk group through a 13-score threshold value, and the 28-day survival rate difference is significant (plt; 0.05) of the method. An efficient and convenient early risk assessment tool is provided for critical candida patients, and clinical precise intervention and prognosis improvement are assisted.

The inhalation suspension preparation containing the SGC receptor stimulant comprises the SGC receptor stimulant with an effective therapeutic dose or pharmaceutically acceptable salt of the SGC receptor stimulant, and pharmaceutically acceptable auxiliary materials of the suspension preparation, the pharmaceutically acceptable auxiliary materials of the suspension preparation comprise at least one of a surfactant, a pH regulator, an osmotic pressure regulator and a metal complexing agent; the inhalation suspension preparation containing the riociguat shows good lung absorption efficiency, is beneficial to reaching the same or better treatment level by reducing the administration dosage, can directly act on a diseased region through an administration route, takes effect more quickly compared with oral administration of the riociguat, and has a good application prospect. Gastrointestinal discomfort and systemic hypotension side effects caused by gastrointestinal tract contact and absorption entering a circulatory system can be avoided, the treatment cycle of an oral dosage form dosage titration administration scheme is shortened, and a better treatment scheme is provided for relieving dyspnea and syncope symptoms of pulmonary hypertension patients treated at home.

The invention discloses a dynamic area adjustment-based surgical operation box and a fluid self-adaptive control method thereof.The dynamic area adjustment-based surgical operation box comprises a box body, a fluid circulating system and a control system, the box body comprises at least two sets of wall plates capable of relatively moving, and the wall plates are connected through a telescopic guide mechanism to form a variable-volume cavity; an area adjustment driving assembly is arranged between the wall plates and comprises a linear actuator and a displacement sensor; the fluid circulation system comprises a fluid pump communicated with the variable volume cavity, a pressure regulating valve and a multi-parameter sensor group; the multi-parameter sensor group comprises a pressure sensor, a flow sensor and a temperature sensor; the control system comprises a main control module and a self-adaptive algorithm module, the main control module is connected with the area adjustment driving assembly and the fluid circulation system, and the self-adaptive algorithm module is configured to establish a dynamic balance model, output a cooperative control signal through a resolving model and preferentially trigger a wallboard displacement compensation mechanism when it is detected that pressure fluctuation exceeds a threshold value.

A method of operating an implantable blood pump including connecting the implantable blood pump to a primary controller, the primary controller being configured to operate the implantable blood pump, and a secondary controller. The secondary controller synchronizes its own motor drive signals to a frequency and phase of the primary controller's motor drive signals, without actively contributing power to the implantable blood pump. An imminent or actual disconnection event is detected in which the primary controller is disconnected from the implantable blood pump. Uninterrupted operation of the implantable blood pump is continued with the secondary controller.

The present invention relates generally to improved systems and methods for removing undesirable material residing in vessels. More specifically, the present invention relates to systems and methods for using at least one cannula to remove substantially en bloc, from a site of obstruction or interest, undesirable material without fragmentation and without excessive fluid loss.

An implantable LVAD system includes an implantable LVAD including an outflow cannula, which is couplable in fluid communication with a circulatory system of the patient at a first site; and an inflow cannula, which is couplable in fluid communication with the circulatory system at a second site upstream of the first site. The LVAD further includes a continuous-flow pump includes a first inlet in fluid communication with the inflow cannula, and a first outlet. The LVAD still further includes a pulsatile-flow pump includes a second inlet in fluid communication with the first outlet of the continuous-flow pump, and a second outlet in fluid communication with the outflow cannula. Control circuitry is configured to activate the continuous-flow pump to provide flow without synchronization with cardiac cycles of a heart of the patient, and activate the pulsatile-flow pump to provide pulsatile flow synchronized with the cardiac cycles. Other embodiments are also described.

The present invention provides an aggregate, a preparation method thereof, and an oral insulin formulation. Specifically, an aggregate formed by the assembly of a chalcogen heterocyclic compound and insulin is provided. The aggregate can be further prepared into an oral insulin formulation. The oral formulation can be used to lower the blood glucose level of mammals and is used as part of a diabetes treatment regimen. The chalcogen heterocyclic compound in the oral insulin formulation prepared by this method can effectively protect insulin from overcoming the three major physiological barriers of the oral intake route, is stable in the gastrointestinal environment, and undergoes a dynamic chemical exchange reaction with the sulfhydryl groups of intestinal mucin in intestinal fluid and the proteins on the inner and outer sides of the epithelial cell membrane through the surface poly-chalcogen molecular bond, entering the circulatory system from intestinal epithelial cells and playing a role in lowering blood glucose. When the oral insulin formulation is administered orally, it has high bioavailability and good blood glucose lowering effect in mammals and can be used for the treatment of diabetes.

The invention discloses an automatic liquid supplementing device used in the TGV electroplating process and an electroplating system and method. The automatic liquid supplementing device comprises an electroplating cavity, an external tank body, a circulating system, a potential applying assembly, a conductivity sensor and a control module. The external tank body is divided into a left cavity (provided with a soluble anode) and a right cavity (communicated with the electroplating cavity) through an ionic membrane, and the cation concentration of the right cavity is the same as that of the electroplating cavity; the potential applying assembly can adjust the potential difference of the left and right chambers according to electroplating working conditions; the conductivity sensor detects the conductivity of the electroplating liquid in real time, the control module determines the cation consumption based on the conductivity, and the flow velocity and potential difference of the circulating system are adjusted in a closed-loop mode. According to the method, automatic, continuous and accurate supplement of positive ions is achieved through the synergistic effect of concentration difference diffusion and potential difference in combination with closed-loop control, the problems that in the prior art, manual supplement is tedious, concentration fluctuation is large, supplement lags behind and the like are solved, and the stability of the electroplating liquid, the TGV hole filling yield and the uniformity of a plating layer are effectively improved.

The embodiment of the invention provides a refrigerant supplement control method and device, refrigeration equipment and a computer readable storage medium. The refrigeration equipment comprises a refrigeration circulation system and a refrigerant supplement device. The refrigerant supplement control method comprises the steps that the outdoor environment temperature and the compressor frequency, the condenser outlet pressure and the evaporator inlet pressure of the refrigeration cycle system are obtained; according to the outdoor environment temperature, the compressor frequency, the condenser outlet pressure and the evaporator inlet pressure, the pressure deviation between the actual pressure and the target pressure of the refrigeration cycle system is calculated; and when the duration time when the absolute value of the pressure deviation between the actual pressure and the target pressure is larger than a pressure deviation threshold value reaches first preset time, the refrigerant supplementing device is controlled to supplement refrigerants to the refrigeration circulation system.