332 results about "Circulatory system" patented technology

The invention relates to the technical field of health management of old people, and discloses a method and a system for predicting multiple diseases of old people. The method comprises the following steps: acquiring multi-modal health monitoring data of a target old person in a preset time period, wherein the multi-modal health monitoring data comprises physiological index time sequence data, a medication record sequence and a daily activity ability evaluation result; and performing cross-modal correlation analysis on the multi-modal health monitoring data to generate a disease interaction characteristic matrix containing metabolic disease correlation degree, circulatory system disease coordination index and neurodegenerative disease progress rate. And performing hierarchical clustering processing on the feature matrix by adopting a dynamic weight distribution algorithm, and outputting potential common disease combinations of the target old people and a priority score of each common disease combination. And generating a personalized intervention strategy set including a drug interaction avoidance scheme, a rehabilitation training intensity adjustment scheme and a nutrition intake ratio scheme according to the priority score.

A method for capturing dislodged vegetative growth during a surgical procedure is provided. The method includes maneuvering, into a circulatory system, a first cannula having a distal end and an opposing proximal end, such that the first cannula is positioned to capture the vegetative growth en bloc. A second cannula is positioned in fluid communication with the first cannula, such that a distal end of the second cannula is situated in spaced relation to the distal end of the first cannula. A suction force is provided through the distal end of the first cannula so as to capture the vegetative growth. Fluid removed by the suction force is reinfused through the distal end of the second cannula. Subsequent to becoming dislodged, the vegetative growth is captured by the first cannula. A method for capturing a vegetative growth during removal of a pacemaker lead is also provided.

The invention provides a damp heat-oxygen-internal pressure-load coupled non-metal pipeline aging device and a method capable of evaluating the service life of an in-service non-metal pipeline. The non-metal pipeline aging device comprises six parts, namely an inner cavity, a box body temperature control system, a box body humidity control system, a pipeline internal pressure control system, a pipeline external load loading device and an air supply circulating system, and an accelerated aging test of a non-metal pipeline under different working condition combinations of four factors, namely damp heat, oxygen, internal pressure and load can be carried out by virtue of the aging device. Measuring oxidation induction periods before and after aging of the in-service non-metal pipeline and the non-metal pipeline with the same mark through a differential heat scanning method, substituting the oxidation induction periods into a non-metal pipeline aging life prediction formula coupled with damp heat-oxygen-internal pressure-load factors, and calculating to obtain the service aging life. According to the method, damp heat-oxygen-internal pressure-external load multi-factor coupling is realized, so that an actual service environment is accurately simulated, and comprehensive technical support can be provided for safe operation of the non-metal pipeline.

The present invention relates generally to improved systems and methods for removing undesirable material residing in vessels. More specifically, the present invention relates to systems and methods for using at least one cannula to remove substantially en bloc, from a site of obstruction or interest, undesirable material without fragmentation and without excessive fluid loss.

The invention relates to the technical field of data analysis, can be applied to business system platforms of financial science and technology, medical treatment and health and the like, and discloses a human body state characteristic value analysis method, device and equipment and a medium. Performing system state analysis on an endocrine system, a circulatory system and a respiratory system of the user according to the physical examination data to obtain a system state characteristic value set, constructing a physiological index vector and a disease course characteristic vector according to the physical examination data, and constructing a complication incidence matrix according to case data; performing complication association analysis on the user according to the physiological index vector, the disease course feature vector and the complication association matrix to obtain a complication feature value, analyzing a criticality feature value of the user according to a system state feature value set and the complication feature value to obtain a hazard feature value set, and performing weighted summation on the hazard feature value set to obtain a complication feature value set; and obtaining a human body state characteristic value. And the accuracy of human body state characteristic value analysis is improved.

The present invention relates generally to improved systems and methods for removing undesirable material residing in vessels. More specifically, the present invention relates to systems and methods for using at least one cannula to remove substantially en bloc, from a site of obstruction or interest, undesirable material without fragmentation and without excessive fluid loss.

The invention discloses a disposable isolated organ continuous oxygenation mechanical perfusion circulation system and a working method. A circulation pipeline of the circulation system is provided with a to-be-carried oxygen conveying pipeline and an oxygen-carrying perfusion pipeline; the output end of the organ low-temperature storage container is connected to the to-be-carried oxygen conveying pipeline, and the pump pipe and the oxygenator are arranged on the to-be-carried oxygen conveying pipeline; the organ transfer sleeve assembly is detachably mounted on the organ tray assembly; the organ tray assembly is arranged in a cavity of the organ low-temperature storage container; the output end of the oxygenator is connected to the oxygen-carrying perfusion pipeline, the automatic bubble separator installed on the oxygen-carrying perfusion pipeline is connected to the input end of the organ transfer sleeve assembly, and the pressure sensor is installed on the oxygen-carrying perfusion pipeline. The device has the following advantages: the device has an automatic bubble removal function; on the basis of a low-temperature mechanical perfusion function, the oxygenation function is achieved; light weight is taken into account, and portable transfer of perfusion equipment is facilitated; the method has higher safety and reliability.

A method of operating an implantable blood pump including connecting the implantable blood pump to a primary controller, the primary controller being configured to operate the implantable blood pump, and a secondary controller. The secondary controller synchronizes its own motor drive signals to a frequency and phase of the primary controller's motor drive signals, without actively contributing power to the implantable blood pump. An imminent or actual disconnection event is detected in which the primary controller is disconnected from the implantable blood pump. Uninterrupted operation of the implantable blood pump is continued with the secondary controller.

The present invention relates generally to improved systems and methods for removing undesirable material residing in vessels. More specifically, the present invention relates to systems and methods for using at least one cannula to remove substantially en bloc, from a site of obstruction or interest, undesirable material without fragmentation and without excessive fluid loss.

An implantable LVAD system includes an implantable LVAD including an outflow cannula, which is couplable in fluid communication with a circulatory system of the patient at a first site; and an inflow cannula, which is couplable in fluid communication with the circulatory system at a second site upstream of the first site. The LVAD further includes a continuous-flow pump includes a first inlet in fluid communication with the inflow cannula, and a first outlet. The LVAD still further includes a pulsatile-flow pump includes a second inlet in fluid communication with the first outlet of the continuous-flow pump, and a second outlet in fluid communication with the outflow cannula. Control circuitry is configured to activate the continuous-flow pump to provide flow without synchronization with cardiac cycles of a heart of the patient, and activate the pulsatile-flow pump to provide pulsatile flow synchronized with the cardiac cycles. Other embodiments are also described.

The invention discloses an automatic liquid supplementing device used in the TGV electroplating process and an electroplating system and method. The automatic liquid supplementing device comprises an electroplating cavity, an external tank body, a circulating system, a potential applying assembly, a conductivity sensor and a control module. The external tank body is divided into a left cavity (provided with a soluble anode) and a right cavity (communicated with the electroplating cavity) through an ionic membrane, and the cation concentration of the right cavity is the same as that of the electroplating cavity; the potential applying assembly can adjust the potential difference of the left and right chambers according to electroplating working conditions; the conductivity sensor detects the conductivity of the electroplating liquid in real time, the control module determines the cation consumption based on the conductivity, and the flow velocity and potential difference of the circulating system are adjusted in a closed-loop mode. According to the method, automatic, continuous and accurate supplement of positive ions is achieved through the synergistic effect of concentration difference diffusion and potential difference in combination with closed-loop control, the problems that in the prior art, manual supplement is tedious, concentration fluctuation is large, supplement lags behind and the like are solved, and the stability of the electroplating liquid, the TGV hole filling yield and the uniformity of a plating layer are effectively improved.

The embodiment of the invention provides a refrigerant supplement control method and device, refrigeration equipment and a computer readable storage medium. The refrigeration equipment comprises a refrigeration circulation system and a refrigerant supplement device. The refrigerant supplement control method comprises the steps that the outdoor environment temperature and the compressor frequency, the condenser outlet pressure and the evaporator inlet pressure of the refrigeration cycle system are obtained; according to the outdoor environment temperature, the compressor frequency, the condenser outlet pressure and the evaporator inlet pressure, the pressure deviation between the actual pressure and the target pressure of the refrigeration cycle system is calculated; and when the duration time when the absolute value of the pressure deviation between the actual pressure and the target pressure is larger than a pressure deviation threshold value reaches first preset time, the refrigerant supplementing device is controlled to supplement refrigerants to the refrigeration circulation system.

A blood circulation system for an extracorporeal blood treatment machine includes: an arterial circulation section; a venous circulation section; a dynamic bubble trap; and an air separator. The blood circulation system conducts blood, during the operation of a blood pump of the extracorporeal blood treatment machine, from a patient to a dialysis unit and from the dialysis unit to the patient. The blood circulation system also includes a recirculation or branch line connected to the bubble trap in order to return part of the blood that flows into the bubble trap into the blood circulation system, upstream of the bubble trap. An extracorporeal blood treatment machine includes the blood circulation system.

The utility model provides a nasal cavity irrigation circulation system, and relates to the field of medical instruments. The system comprises at least one flushing pump, at least one suction pump, a flushing pipeline system and a circulating pipeline system, in the flushing mode, the flushing pump pumps first liquid through the first liquid supply pipeline and supplies the first liquid to the nasal cavity on one side, and the suction pump discharges the liquid pumped out of the nasal cavity on the other side to the dirty liquid box through the first discharge pipeline. In the circulation mode, the flushing pump pumps second liquid through the second liquid supply pipeline and supplies the second liquid to the nasal cavity on one side, and the suction pump discharges the liquid pumped out of the nasal cavity on the other side to the circulation box through the second discharge pipeline; through an independent pipeline system in the system, switching between a flushing mode and a circulating mode can be achieved; the problem that in the process that a patient uses circulating equipment, excessive nasal endocrine and attached pathogens of the patient are prone to being attached to the pipeline in the equipment, and the pipeline is not thoroughly disinfected through disinfectant is solved.

There is provided a barrier valve device for a completion string. The device comprises a circulation system and a barrier system. The circulation system comprises an opening in the wall and a first valve for permitting or preventing fluid flow through the opening in the wall between a first portion of a bore of the device and outside of the device. The barrier system comprises a second valve for preventing or permitting longitudinal fluid flow through the bore between the first portion and a second portion. The device is configurable in an initial state, an intermediate state, and a final state. In the initial state, the first valve open and the second valve is closed. In the intermediate state, the first valve is closed and the second valve is closed. In the final state, the first valve is closed and the second valve is open.

The systems and methods of the present invention can remove target material (including blood clots) from body parts (including but not limited to the circulatory system) for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebral vascular embolism, and other vascular obstructions. The capture system may include a tubular body and an end having an opening and a capture guide. In some embodiments, the body or funnel tip of the catheter is expandable.

The present invention discloses a double-stage amplified DNA cascade circulation system and its application, which constructs a precise imaging system through CAR+CHA+HCR. The target is calculated by the "CAR" combination chain to determine whether to release miR-21, thereby achieving accurate detection of cancer cells. The amplification system consists of a "CHA+HCR" double cycle, where CHA consists of hairpin probes H1 and H2. When miR-21 is present, the CHA cycle is opened, and the formed H1 and H2 duplexes open the HCR cycle, thereby displaying a fluorescent signal. The HCR cycle consists of H3, H 3free The two cycles each perform their own functions and complement each other, ultimately forming a large CHA+HCR system, which further enhances the fluorescence signal.

The invention discloses a coronary artery hemodynamic information prediction method, device and equipment, a medium and a product, and relates to the field of biomechanics, and the method comprises the steps: obtaining clinical data, and segmenting the clinical data to obtain a coronary artery three-dimensional model and a heart three-dimensional model; constructing a human body blood circulation system lumped parameter model; determining a personalized human body blood circulation system lumped parameter model of the patient after assignment; constructing a 0-3-dimensional myocardial mechanical coupling model; constructing a first database; obtaining personalized systolic function parameters and diastolic function parameters of the patient based on the first mapping network; constructing a blood vessel 0-3-dimensional coupling model; constructing a second database; obtaining personalized coronary flow field information of the patient based on a second mapping network; the personalized coronary flow field information comprises a pressure field, a velocity field and concentration polarization characteristics of low-density lipoprotein on a blood vessel wall surface. Through network architecture innovation, the bottleneck of the model in the aspects of efficiency and personalization is solved, and the diagnosis precision of the coronary heart disease is improved.

This invention relates to the field of biopharmaceutical manufacturing technology, and discloses a BCMA-targeting nanobody, its preparation method, and its application. The nanobody comprises a heavy chain single-domain binding domain, a helical conformation-constrained peptide chain, and an amphiphilic self-assembled polypeptide sequence. The helical conformation-constrained peptide chain forms a steric barrier between the binding domain and the polypeptide sequence through physical length, maintaining the monomeric conformation of the polypeptide sequence in a free state. When the binding domain is anchored at the receptor binding interface, the conformation-constrained peptide chain increases the local effective concentration of the polypeptide sequence within the confined space, inducing intermolecular topological assembly. This invention utilizes a kinetic phase transition mechanism to generate a binding state jump, maintaining the conformational activity of the composition in the circulatory system, reducing off-target toxicity, and prolonging the residence time at the receptor interface.

The invention relates to a preparation method of a placenta trophoblast-derived transporter and application of the placenta trophoblast-derived transporter in a medicine for treating spontaneous abortion, which comprises the following steps of: taking out a placenta of a suckling mouse, cutting the placenta into fine tissue blocks, resuspending by using digestive juice, digesting in a water bath kettle at 37 DEG C for 20 minutes, and then stopping digestion by using 1640 culture containing high-temperature heat-inactivated fetal calf serum; diluting and neutralizing collagenase digestive juice according to 5 times of volume; and centrifuging the collagenase digestive juice for multiple times to obtain a precipitate, namely the exosome. And carrying out density gradient centrifugation on the coarse migration body by using Optiprep as a density medium, washing, precipitating and centrifuging by using PBS on an ultra-high-speed centrifuge by using a horizontal rotor to obtain the placental trophoblast source migration body. The invention finds that the generation of the placental trophoblast cell source migration body is related to the physiological process of pregnancy for the first time, and the placental trophoblast cell source migration body can enter the circulatory system and reach the placenta through in-vitro supplementation.

The application provides an atomizer, which comprises a liquid bottle, a flow limiting device and an atomizing system, the liquid bottle, the flow limiting device and the atomizing system form a circulation system, liquid in the liquid bottle can spontaneously enter the atomizing system through the flow limiting device under the action of gravity, and is diffused into air after being atomized by the atomizing system, the atomizing system has a liquid inlet and a discharge outlet, and the discharge outlet of the atomizing system is communicated with the liquid bottle, the atomizer has the advantages of simple structure, difficulty in discoloration, peculiar smell, mixed smell and liquid leakage, and the atomizer has the advantage of more energy saving.

The utility model relates to an adult simulation load device for online calibration of an extracorporeal membrane oxygenation system. The system comprises a left ventricular artery system simulation box, a right atrial vein system simulation box, a resistance device, a V-A ECMO treatment mode artery perfusion cannula, a V-V ECMO treatment mode vein perfusion cannula, a vein drainage cannula, a bottom plate, a right atrial vein system simulation box hydraulic monitoring sensor, a left ventricular artery system simulation box hydraulic monitoring sensor and a manual pressure release valve. And a ball valve pressurizing device and a vertical partition plate. The left ventricular artery system simulation box, the resistance device and the right atrial vein system simulation box are sequentially connected through pipelines. The device is simple in structure, convenient and practical to operate and capable of accurately simulating the blood volume of a patient, the pressure difference between a venous system and an arterial system and the resistance of a blood circulation system when an adult patient adopts a V-A ECMO treatment mode and a V-V ECMO treatment mode respectively, and has practical value; calibration data has clinical guiding significance, the measurement accuracy of key parameters of equipment is effectively guaranteed, and clinical risks are reduced.

The utility model discloses a material circulating system. A placing rack is provided with a material placing station and a material taking station; the stock bin module is arranged on the containing frame and used for containing materials. Each carrier is provided with a material cavity used for containing materials. The feeding module is used for taking out materials in the stock bin module and placing the materials in a material cavity of the carrier located at the discharging station. The detection module is used for detecting whether materials are placed in the material cavity of each carrier located on the discharging station or not. The driving module is arranged on the placing frame and is used for transferring the carrier with the materials placed in the material cavity from the material placing station to the material taking station according to the detection result of the detection module and remaining the carrier without the materials placed in the material cavity at the material placing station; the material taking module is used for taking out materials in the carrier located on the material taking station, and the driving module is used for conveying the carrier located on the material taking station to the material placing station after the material taking module takes out the materials. According to the manufacturing method, the manufacturing efficiency of the medical catheter assembly is improved.

A piston assembly for a fluid circulation system includes a piston housing separated by a piston (70) into a first chamber and a second chamber. A piston (70) fluidly separates the first chamber from the second chamber and is movable to vary the volume of the first and second chambers. At least one chamber includes two fluid ports spaced apart from each other. When the piston (70) moves to one side of the first chamber, a passage (82a) on the piston communicates the two fluid ports while maintaining a seal of the first chamber from the second chamber. A piston (70) for a piston assembly is also disclosed. A piston (70) provides a bypass passage through the two fluid ports while allowing pressurization of each chamber.

Provided is an extracorporeal circulation system, which includes an arterial sheath, an inflow tube, a handle, an outflow tube, and a venous sheath that are connected in sequence. The arterial sheath is used for connecting to a carotid artery, and the venous sheath is used for connecting to a vein. The handle includes a housing, as well as a flow controller, a blood filter, and a one-way check valve that are arranged in the housing and are communicated in sequence. The flow controller is connected to the end of the inflow tube away from the arterial sheath, and the one-way check valve is connected to the end of the outflow tube away from the venous sheath. The flow controller includes one body element with a flow-through channel and a flow control element. At least part of the flow control element is received in the body element and is movably connected to the flow-through channel. The flow control element reduces or increases the circulation area of the flow-through channel under an external force. Reverse blood flow from the carotid artery to the femoral vein can be established by using the extracorporeal circulation system of the present invention, thereby preventing a falling thrombus from entering the brain during surgery.

The present invention relates to a breathing gas circulation system to be connected to a water chamber of a respiratory assist device to guide a heated / humidified breathing gas to a patient, wherein a circuit unit comprises: an intake tube, one lengthwise end of which connects to a water chamber so as to communicate therewith, and which delivers a heated / humidified breathing gas to the patient; a branch unit which connects to the other lengthwise end of the intake tube so as to communicate therewith, and which connects to a breathing mask worn on the patient, so as to communicate therewith; and a discharge tube, one lengthwise end of which connects to the branch unit so as to communicate therewith, and the other lengthwise end of which connects to an artificial respirator to guide thereto the gas generated subsequent to the breathing of the patient.

The present disclosure features imaging media including a contrast agent encapsulated within a biodegradable nanoparticle matrix. The particles are sized such that they avoid excretion via urinary excretion (e.g., at least 5 nm in diameter) during an imaging procedure or an image-guided procedure. Instead, the particles are predominantly removed from circulation by the reticuloendothelial system of the liver. This results in a buildup of contrast agent in the liver, allowing for a highly specific imaging modality for liver imaging. Further, the bulk of the imaging media is excreted into the bowel, reducing in-vivo toxicity of the imaging media. Finally, because of their size, the nanoparticles of the imaging media have a higher circulation half-life.

The application provides a circulating system equipped with a diving cylindrical linear induction electromagnetic pump, the electromagnetic pump is arranged in a container filled with liquid metal in a longitudinal direction, an inert gas tank is arranged for sealing, and a heat dissipation fin structure is arranged outside an external stator of the electromagnetic pump. The diving electromagnetic pump circulating system significantly reduces the floor area and weight of the liquid metal circulating loop, greatly improves the service life of the liquid metal circulating loop under different working conditions, and can effectively solve the requirements of equipment in robustness and light weight in extreme environments such as deep sea and deep space.

1. Name of the product in this design: Display screen panel with a graphical user interface for disease screening. 2. Purpose of this design: To display a graphical user interface. 3. The key design features of this product are its graphical user interface. 4. The image or photograph that best illustrates the design's key features: the front view. 5. The display screen panel uses a standard design, omitting other views. 6. Purpose of the graphical user interface: Used for screening diseases after a physical examination. Human-computer interaction and state changes in the graphical user interface: The upper part of the main view displays a 3D human body model, and the "Respiratory System" button is lit. The lower part displays a floating window introducing the symptoms corresponding to the respiratory system. Swiping left or right on the 3D human body model in the main view allows you to rotate and view the model. For example, swiping left on the 3D human body model leads to state change diagram 1. Clicking the "Circulatory System" button in the main view leads to state change diagram 2. The lower part of state change diagram 2 displays a floating window introducing the symptoms corresponding to the circulatory system. Swiping up on the floating window in state change diagram 2 leads to state change diagram 3, where the floating window becomes longer. Swiping down on the longer floating window in state change diagram 3 returns you to state change diagram 2. In the interface change state diagram 3, the gray blocks represent replaceable content screens. 7. Other situations requiring explanation: This display panel can be used with desktop computers, laptops, tablets, televisions, and mobile phones.

The present invention relates generally to improved systems and methods for removing undesirable material residing in vessels. More specifically, the present invention relates to systems and methods for using at least one cannula to remove substantially en bloc, from a site of obstruction or interest, undesirable material without fragmentation and without excessive fluid loss.