548 results about "Needle free" patented technology

A vial adapter having a needle-free valve, a sharpened cannula used to perforate a vial's rubber stopper, and a circular array of claws of different lengths to engage vial closures of different diameters. The array of claws includes a first set of claws each having a first length extending inwardly from the periphery of the housing of the adapter and a second set of claws alternating with the first set of claws and each having a longer length. The second set of claws are mounted so that they deflect and plastically deform out of the way in the case where the adapter is engaged with a vial that exceeds a predetermined size. The housing includes a shroud that is at least as long as the sharpened cannula to protect medical personnel who use the adapter from inadvertent punctures. The needle-free valve includes a resiliently deformable piston element with a naturally open bore. The interior of the piston provides a fluid flow path through the adapter. In one embodiment, the first set of claws of the adapter may be used with a vial closure of at approximately 20 mm in diameter and the second set of claws may be used with a vial closure of approximately 13 to 17 mm in diameter.

Method and surgical instrument for treating prostate tissue including a surgical instrument having a main body, a needle deployment port, a needle, first and second handles and a lockout release mechanism to limit needle extension. Additionally, a kit includes the surgical instrument, together with a cystoscope, and optionally a syringe and reservoir of ethanol. The method includes needle-less injection and visualizing the ethanol injection by delivering both an echogenic agent and ethanol either by needle or needle-less injection or by providing an ultrasonically visible marker near the tip of the ethanol delivery cannula. The method also includes extending the needle transversely of the instrument housing using a link assembly.

A catheter integral with a valved needle-free connector provides a safety catheter device configured to receive a blunt cannula and sharp needle forming an insertion mechanism. The sharp needle is mounted within a needle tube and a control handle is used to slide the sharp needle out of and into the protective needle tube. When the insertion mechanism is mounted to the connector and the control handle is used to slide the sharp needle out of the tube, a blunt cannula first moves into contact with and enters the bore of the valve mechanism of the connector opening it and protecting it from damage that may be caused by the sharp needle. The sharp needle is then extended through the connector and extends out the distal end of the catheter so that a venipuncture procedure may be performed to properly locate the catheter in the patient's circulatory system. Once located, the needle may be retracted into the insertion mechanism, the insertion mechanism disconnected from the connector, and discarded.

A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.

A septum (1) is held in the cavity of a cover (6) and mounted on a pedestal (7) forming part of a flow channel, and comprises a main body having a through passageway and compression ribs formed in the sides thereof. In the main body, the vertical diameter of the cross section orthogonal to the through passageway is longer than the transverse diameter, and the through passageway includes a vertical diameter direction slit (4) formed in the vicinity of the outer end surface of the main body, and a hole (5) that is formed in a region extending from the slit to the inner end surface of the main body and whose cross section is spindle-shaped having a longer axis extending in the vertical diameter direction. The compression ribs are formed in the opposite sides of the main body in the transverse diameter direction, and the cavity of the cover is of circular cross section whose diameter is shorter than the outer surface spacing between the compression ribs. With the septum mounted, a space is defined between part of the surface of the main body and the inner wall surface of the cover. Further, the hole is closed by a compressive force acting on the septum from the inner wall surface of the cover through the compression ribs. The through passageway in the septum hardly forms a dead space that would cause a residual liquid therein, and the slit in the septum surface hardly opens even at the time of pressurization.

A needle-free medical connector includes a housing with a first port and a second port. The connector also includes a piston element defining a fluid passageway between the first and second ports. The piston element is movable between flow and non-flow positions. The piston element has an expandable section having a variable inner width and volume that forms a part of the flow path through the connector. As the piston is compressed to the flow position, the expandable section is expanded in width by movement over a flow post thereby maintaining or increasing the volume of the fluid passageway through the connector. The expandable section has a configuration permitting the continuous flow of fluid through its entirety.

An apparatus for the handling of hazardous fluids includes a collection vessel, a collection vessel connector, a dose control connector, a unit dose container, a delivery control connector, and a delivery site access device. The collection vessel contains the fluid prior to dispensing, the unit dose container contains a predetermined amount of the fluid for dispensing, the delivery site access device provides access to an intended delivery site, and the connector attaches pieces of the apparatus to one another. The method of the invention allows needle-free connections to be made for the apparatus, using a predetermined arrangement of the pieces of the apparatus, and in one embodiment, employs deformable elastomeric valves capable of creating a decreased pressure at a valve surface, so that upon closure of said valves, a fluid on the surface on the valves is withdrawn within the connector.

A syringe assembly including an adapter, a sheath and filling spike for connecting to said adapter and an intravenous connector for intravenously administering medicine to a patient. The barrel may be connected to the adapter and the filling spike for filling the barrel with medicine. The medicine can then be injected into a patient through either the needleless intravenous injection system or through a retractable needle assembly.

A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.

A needleless additive control valve for use with a fluid container containing an infusion liquid and having an intravenous (IV) port for administrating the infusion liquid, and an additive transfer device containing a liquid additive and having a male connector for administrating the liquid additive. The needleless additive control valve includes a trifurcated connector body having an IV spike for sealing insertion into the IV port, an outlet port, and a needleless additive port with a female connector for sealingly receiving the additive transfer device's male connector wherein the IV spike, the outlet port and the needleless additive port are in 3 way direct and continuous fluid communication thereby enabling the additive transfer device's liquid additive to be either mixed with the infusion liquid or directly administered to a patient.

A catheter integral with a valved needle-free connector provides a safety catheter device configured to receive a blunt cannula and sharp needle forming an insertion mechanism. The sharp needle is mounted within a needle tube and a control handle is used to slide the sharp needle out of and into the protective needle tube. When the insertion mechanism is mounted to the connector and the control handle is used to slide the sharp needle out of the tube, a blunt cannula first moves into contact with and enters the bore of the valve mechanism of the connector opening it and protecting it from damage that may be caused by the sharp needle. The sharp needle is then extended through the connector and extends out the distal end of the catheter so that a venipuncture procedure may be performed to properly locate the catheter in the patient's circulatory system. Once located, the needle may be retracted into the insertion mechanism, the insertion mechanism disconnected from the connector, and discarded.

A needle free medical connector includes a housing with a first port and a second port. The connector also includes a piston element defining a fluid passageway between the first and second ports. The piston element is movable between flow and non-flow positions. The piston element has a compressible section having a variable inner width that forms a part of the flow path through the connector. As the piston is compressed to the flow position, the compressible section self-expands in width thereby maintaining or increasing the volume of the fluid passageway through the connector. The compressible section has a configuration permitting the continuous flow of fluid through its entirety.

The present invention discloses a medical injector and medicament loading system for use therewith. The medicament loading system includes cap for a medicament cartridge. The cap has a post for causing movement of the cartridge stopper toward the seal when the cap engages the medicament cartridge to thereby eliminate adhesion between the medicament chamber and the stopper. The medical injector according to the present invention includes the medicament loading system, i.e., a cartridge assembly, a needle free syringe assembly, and a power pack assembly.

A vial adapter having a needle-free valve, a sharpened cannula used to perforate a vial's rubber stopper, and a circular array of claws of different lengths to engage vial closures of different diameters. The array of claws includes a first set of claws each having a first length extending inwardly from the periphery of the housing of the adapter and a second set of claws alternating with the first set of claws and each having a longer length. The second set of claws are mounted so that they deflect and plastically deform out of the way in the case where the adapter is engaged with a vial that exceeds a predetermined size. The housing includes a shroud that is at least as long as the sharpened cannula to protect medical personnel who use the adapter from inadvertent punctures. The needle-free valve includes a resiliently deformable piston element with a naturally open bore. The interior of the piston provides a fluid flow path through the adapter. In one embodiment, the first set of claws of the adapter may be used with a vial closure of at approximately 20 mm in diameter and the second set of claws may be used with a vial closure of approximately 13 to 17 mm in diameter.

A needle free medical connector includes a housing with a first port and a second port. The connector also includes a piston element defining a fluid passageway between the first and second ports. The piston element is movable between flow and non-flow positions. The piston element has a compressible section having a variable inner width that forms a part of the flow path through the connector. As the piston is compressed to the flow position, the compressible section self-expands in width thereby maintaining or increasing the volume of the fluid passageway through the connector. The compressible section has a configuration permitting the continuous flow of fluid through its entirety.

The invention provides for a cleansable, i.e., swabbable, access pot, formed by a stopper having a bore extending from an entry position to an exit position; and a plug in the bore at the entry position and movable in the bore; whereby the location of the plug at the entry position of the stopper permits the cleansing or swabbing of the outer surfaces of the plug and the stopper before the plug is depressed into the bore of the stopper for a vial or container in order to reduce the danger of contamination of the bore by pathogens. To convert from single-use vial access, to multiple-use vial access, the plug is replaced by a swabbable, needleless, multiple-use lock connector in which the plug contains a slit that is closed upon initial depression but is thereafter openable to permit flow through the connector into a vial or container.

Vial assemblages having a vial and a pre-attached fluid transfer device for use with a needleless syringe for enabling flow communication between the syringe and the vial. The fluid transfer device includes an elongated tubular flow member having a connector for sealing flow communication with the needleless syringe and a spike having a spike end for puncturing the vial for enabling flow communication between the needleless syringe and vial interior. The spike end is in intimate sealing contact with the vial's stopper. The fluid transfer device also includes a manually removable closure for initially sealing the connector and, on removal, exposing the connector.

The invention discloses a saw tooth type needle-free electrostatic spinning device, which comprises a liquid supply system, a spinning system, a power supply system, a receiving system, a transmission system and a control system. The device is characterized in that the spinning system comprises a spinning manifold body, a spinning component and a center shaft; the exterior of the spinning manifold body has a horizontal cuboidal shape, and a horizontal cylindrical cavity is formed in the spinning manifold body; a main body of the center shaft is arranged in the cavity, and the two ends of the center shaft extend from the spinning manifold body, and are connected with the transmission system; the spinning component has an axially continuous or parallel thin rack structure, and points of a rack are outwards arranged on the center shaft, and can be driven by the center shaft to rotate; distances of 1 to 3mm are reserved between the points and the inner wall of the spinning manifold body; a liquid inlet pipe orifice of the spinning manifold body is communicated with a spinning metering pump of the liquid supply system, and an overflow port of the spinning manifold body is connected to a liquid storage device of the liquid supply system through a pipe, and is reserved between the bottom of the spinning component and the center shaft; and rectangular spinning openings are reserved in positions opposite to the highest parts of the spinning component on the upper surface of the spinning manifold body.

A needle free hypodermic injector comprising a hand manipulatable elongate housing, an impact impulse injection mechanism within the housing, a suction generating means within the housing and cooperable with the impact impulse injection mechanism, a safety interlock mechanism, at least one medicament containing ampule cooperable with the impact impulse injection mechanism and the suction generating means and having a jet orifice through which medicament is injectable through a skin surface in response to an impulse placed on the medicament by the impact impulse injection mechanism, and means to receive and hold the ampule on the injector in registration with the impact impulse injection mechanism and in communication with the suction generating means; whereby the injector is adapted to expel the medicament from the ampule in a jet stream of sufficient velocity to penetrate skin tissue held against the orifice by the suction generating means and to deposit the medicament intradermally, subcutaneously or intramuscularly based on the position and angle of the jet orifice.

Systems and methods are described for treating un-met medical needs in migraine and related conditions such as cluster headache. Included are treatments that are both rapid onset and long acting, which include sustained release formulations, and combination products. Also included are treatments for multiple symptoms of migraine, especially headache and nausea and vomiting. Systems that are self contained, portable, prefilled, and simple to self administer at the onset of a migraine attack are disclosed, and preferably include a needle-free injector and a high viscosity formulation, to eliminate such issues as fear of self administration with needles, and needle stick and cross contamination.

This invention provides a female medical coupling port with an integrated port guide to enable more accurate and precise coupling of a male port coupling (such as the cannula of a syringe) and to prevent port exposure to non-sterile objects. The male and female ports can be arranged according to standard dimensions for male and female luer taper fittings recognized by ANSI and by ISO. This guide-shielded port is usable with the standard ANSI and ISO male cannula widely used in the medical field. In an embodiment the female port is used in medical fluid systems to receive a blunt male cannula, such as those found in the luer lock fitting of needle-less syringes and IV tubing systems to establish a mechanical coupling. Female ports allow coupling of devices (e.g. syringes and IV tubing) to a variety of medical applications including stopcocks, minimum fluid displacement medical couplings, female-to-female adapters, port dead-end caps, IV extension sets, pressure-monitoring devices, etc. The port guide can be constructed as a unitary part of the port, or can be a retrofittable structure that is either snapped into place on, for example, a female port stem, or slid onto a port, such as a minimum displacement fluid coupling. Appropriate drain ports can be provided in the port guide to prevent capture of excess fluid.

A device for delivering a drug includes a housing; at least one nozzle at a portion of the housing; a source of drug in the housing; and an energy source for providing a pressure of up to about 2,000 psi for driving the drug through the at least one nozzle and out of the housing. The drug is delivered to tissue under microjet propulsion. The device is particularly useful for drug delivery applications such as transdermal and ocular by way of example.

A one way valve assembly has an inlet and an outlet, the inlet forming one end of a tubular passageway, a valve member which is slideable along the tubular passageway between a closed position where fluid is unable to flow through the valve assembly, and an open position, the valve member having an outer end and an inner end, and biasing means to bias the valve member to the closed position, characterized in that when the valve member is in the closed position, the outer end is substantially at the inlet of the valve assembly to close of the tubular passageway and to allow the inlet area to be sterilized.

Aqueous cyclodextrin-free solution of meloxicam suitable for administration by needleless injection, containing a pharmacologically acceptable meloxicam salt of an organic or inorganic base and one or more suitable excipients, the content of dissolved meloxicam salt being from 35 to 100 mg / ml. The formulation according to the invention has a shelf-life of up to 24 months or more.

A needle-free transdermal transport device includes a chamber (900) for holding the substance to be injected, a nozzle (910) in fluid communication with the chamber, and a drug reservoir (950) for storing the substance to be transferred to the chamber. The needle-free transdermal transport device also includes a controllable magnet and coil electromagnetic actuator (242) in communication with the chamber. The actuator receives an electrical input and generates in response a force. The force then causes a needle-free transfer of the substance from the chamber to the biological body. The force is variable responsive to variations in the received input during actuation. The actuator draws the substance from the drug reservoir or alternatively, the substance can be pressurized from the drug reservoir into the chamber by a pressure source.

Embodiments of luer-type needle-free valve devices are disclosed. One of the novel aspects of the invention is its ability to transform from an open state to a closed state. The open position eliminates the potential for a differential pressure to exist between the volume connected to the inlet and outlet of the valve fitting. The closed position enables the device to maintain a differential pressure between the volume connected to the inlet and outlet of the valve fitting. The invention is useful in manufacturing sterile medical devices by allowing all surfaces to communicate with the sterilizing agent when the valve is in an open configuration when it is in a closed position.

Formulations are described that are viscous and will benefit from needle-free delivery at high driving pressures. Conventional delivery of these viscous formulations by hypodermic syringes is inconvenient as well as painful. Formulations include those which have a viscosity of about 5 cS or more at about 20° C. and which can have 0.5 ml or more administered by a needle-free injector in about 0.1 second±0.02 seconds.

A needleless connector for controllably permitting fluid communication between a cannula and a port usually associated with a patient catheter or line. The connector is made from three parts, two of which form an elongated housing for a valve part. The valve part comprises a domed slit valve which is in a closed state before a cannula is inserted into the housing. Insertion of the cannula inverts the dome valve to open a slit permitting fluid communication there through. Insertion of the cannula also displaces the valve part about and along a post internally disposed in the housing. Assembled, the valve part is initially disposed about the post in a compressive sealed relationship to form a secure pathway therebetween. The post is shaped to store greater energy by stretching portions of the valve part as the valve part is displaced therealong. Upon removal of the cannula, stored energy is released from the stretched portion of the valve part to return the valve part to an original state, presenting a closed and cleanable surface to a user.