433results about "Jet injection syringes" patented technology

The invention relates to an injection device (100) with needle for injecting a product, in particular a cosmetic product, the device comprising: a suction chamber (1), a support surface (4) inside the chamber (1) at a position set back from the opening (2), and a suction source, the support surface (4) comprising at least one microneedle (6) for carrying out the injection, the suction opening (2) is closed by an intermediate component (7), defining a contact surface with the target area (3), and having at least one orifice (8) designed to be passed through by the microneedle (6), when the target area (3) is suctioned towards the chamber (1).

A dispensing device for dispensing a beneficial agent configured to transition between an inactive state and an active state. The dispensing device can include a body, a pressure chamber, a primary container, and / or a diaphragm. The pressure chamber and diaphragm may both be disposed within the body, and the primary container may be disposed within the pressure chamber and engaged with the diaphragm. The primary container may include a distal end with a septum or pierceable fitment disposed on a distal side of the diaphragm. The dispensing device may be configured to transition between an inactive state and an active state when a pressurized fluid is provided to the pressure chamber by moving the primary container distally against the diaphragm to cause the diaphragm to deform, including stretching a section of the diaphragm in a distal direction.

The invention discloses an ultra-high-speed jet flow drug delivery device, and relates to the technical field of drug delivery, and the ultra-high-speed jet flow drug delivery device comprises a jet flow parameter setting module which is used for determining the direction and speed of jet flow according to drug delivery requirements; the high-energy current module is used for generating high-energy current, enabling the metal wire to instantly reach a high-temperature state and driving the medicine solution to form high-speed fluid; the nozzle is used for converting high-speed fluid into jet flow according to the jet flow direction and speed determined by the jet flow parameter setting module; the sensor module is used for monitoring the distribution condition of the medicine solution in the body in real time; the precise delivery module is used for controlling the jet flow parameter setting module to adjust the jet flow direction and speed in real time according to the distribution condition of the drug solution in the body and in combination with the drug delivery requirement. The high-speed jet flow is formed by adopting an electric explosion technology, strong kinetic energy is provided to effectively penetrate through human tissues, accurate drug delivery to a deep target area is realized, and the drug jet flow is ensured to be accurately delivered to the deep tissues in combination with a sensor.

The invention relates to the technical field of syringes, in particular to a needleless syringe which comprises a mounting unit, a needle fixing unit and a needle fixing unit. The injection unit comprises a liquid storage pipe arranged in the accommodating space and a piston rod arranged in the liquid storage pipe in a sliding manner; the driving unit comprises a driving motor arranged in the containing space, a rotating disc arranged at the end of the driving motor and a push rod arranged on the mounting shell in a sliding mode, and the push rod and the piston rod can generate relative displacement. According to the needleless injector, the control part and the elastic part are matched to control the push rod to move in a reciprocating mode, then the piston rod is controlled to move in a reciprocating mode, liquid medicine in the liquid storage pipe is sucked and discharged, the elastic part controls the push rod to collide with the piston rod when moving, the liquid medicine discharging pressure of the liquid storage pipe is increased, and skin puncturing is facilitated; meanwhile, the moving speed after collision is reduced, the liquid medicine spraying pressure is reduced, and liquid medicine injection is facilitated.

The present application discloses an ultra-high-speed jet drug delivery device, which relates to the field of drug delivery technology and includes: a jet parameter setting module for determining the direction and speed of the jet according to the drug delivery requirements; a high-energy current module for generating high-energy current to make the metal wire reach a high-temperature state instantly, driving the drug solution to form a high-speed fluid; a nozzle for converting the high-speed fluid into a jet according to the direction and speed of the jet determined by the jet parameter setting module; a sensor module for monitoring the distribution of the drug solution in the body in real time; and a precision delivery module for controlling the jet parameter setting module in real time to adjust the direction and speed of the jet according to the distribution of the drug solution in the body and the drug delivery requirements. In the present application, electric explosion technology is used to form a high-speed jet, providing powerful kinetic energy to effectively penetrate human tissue, achieve precise drug delivery to deep target areas, and combine with sensors to ensure that the drug jet is accurately delivered to deep tissues.

The present disclosure relates to a skin treatment device, the skin treatment device comprising: a main body including a control unit that controls the operation of the skin treatment device and a power source unit that supplies power to the medical skin treatment device; a transfer unit for moving the main body; and a handpiece which receives power from the power source unit of the main body, is controlled by the control unit, and has one side that comes into contact with the skin of a patient to radiate therapeutic energy below the skin surface of the patient and thus improve the skin.

The invention relates to the technical field of needleless injectors, in particular to a portable needleless injector, which comprises a mounting unit, an injection unit and a control unit, the force storage unit comprises a moving rod arranged in the mounting cavity in a sliding manner, a first elastic piece arranged between the moving rod and the mounting cavity, and a driving assembly arranged in the mounting cavity and matched with the moving rod; the triggering unit comprises a limiting assembly matched with the moving rod; and the needle head unit comprises a needle tube communicated with the mounting cavity and a piston rod arranged in the needle tube in a sliding manner. According to the portable needleless injector, the moving rod can be controlled by the driving assembly to extrude the first elastic piece and then is limited by the limiting assembly to move, the effect of force storage is achieved, then the moving rod is ejected out under the elastic force of the first elastic piece by making contact with the limitation of the moving rod, and meanwhile the moving rod can control the piston rod to move to extrude and spray out liquid medicine in the needle tube.

Embodiments described herein relate to systems and methods of delivering medicinal components to target regions of an eye of a subject and / or patient. In some aspects, an apparatus includes a housing; a medicament container configured to accommodate a medicinal component; a sensor configured to measure a physical property of a subject; and an injector coupled to the medicament container and configured to produce a stream of the medicinal component directed towards a region of the eye of the subject based on the measured physical property.

The invention relates to the technical field of medical instruments, in particular to an electromagnetic needleless injector which comprises a shell, a nozzle assembly, a liquid storage assembly, a driving assembly and an intelligent control system. Firstly, a series excitation linear motor is adopted to replace a traditional needleless injector driven by a spring, and the problems that driving force is limited and elasticity is attenuated due to the spring are effectively solved. According to the series excitation linear motor, through excitation magnetic field coupling between the stator coil and the rotor coil in the motor, the rotor directly drives the plunger rod to do linear motion in the axial direction so as to complete injection, the structure is simpler, the direct drive type connection structure is adopted, the stability is higher, and force transmission is more accurate. In addition, an intelligent control system integrated in the needleless injector enables the needleless injector to be more intelligent, control precision is higher, operation is more convenient, the needleless injector can be wirelessly connected with a breeding cloud management system, rapid, accurate and painless injection of live pigs and other animals can be achieved, and breeding efficiency and injection safety are improved.

A pre-filled dual-chamber medical agent delivery system assembled and configured to allow delivery of a single dose of a combined therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular design consisting of separately constructed components cooperatively arranged and coupled to one another, such as to facilitate delivery of a reconstituted lyophilized agent to a patient.

An injector including: a housing, a cap detachably coupled to the housing, a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly including a trigger engagement member, an energy source associated with the ram for powering the ram to expel medicament from the medicament container, a trigger member disposed about an axis, the trigger member moveable between a pre-firing configuration and a firing configuration, wherein medicament is expelled from the medicament container when the trigger member is in the firing configuration, a needle guard moveably coupled to the housing, the needle guard movable between a storage position and a pre-injection position, wherein the needle guard moves from the storage position to the pre-injection position as the cap is detached from the housing.

The present invention relates to a needleless syringe comprising a body part and a nozzle part, wherein the body unit provides a pulse-type pressure of a predetermined magnitude to a drug accommodated in a drug accommodation unit in the nozzle unit, and the nozzle unit discharges, in the form of a microjet through a nozzle hole of the nozzle unit, the drug accommodated in the drug accommodation unit in response to the pulse-type pressure provided by the body unit. A nozzle unit-side connection unit in the nozzle unit, which is mounted on a connection unit of the body unit, includes an information unit configured to store, as tag information, information on equipment parameters for the operation of the needleless syringe. The body unit is provided with: a sensor capable of recognizing the information unit provided in the nozzle unit; and a control unit that automatically sets the equipment parameters for controlling the operation of the needleless syringe, on the basis of the tag information recognized by the sensor.

The invention relates to a powder needleless injection pressure monitoring device, which belongs to the technical field of medical instruments and comprises a pressure sensing needleless injector main body, a partition pressure reading recording display screen, a main body pressure sensor and a pressure sensing medicine tube. The powder needleless injection pressure monitoring device is provided with a medicine tube pressure intensity monitoring structure, an injector injection generation pressure sensing structure and a pressure value display structure at the same time; the pressure sensors arranged at the top of the injection push rod and the upper end of the injection piston push piece are used for accurately sensing the injection generation pressure intensity and the actual acting pressure intensity value, the real-time pressure during needleless injection is sensed and displayed, the actual pressure value of powder needleless injection can be accurately monitored, effective injection is guaranteed, and the injection efficiency is improved. The action pressure intensity verification sensor is used for sensing the actual action and the maximum pressure intensity value of the medicine powder, and the maximum pressure intensity value is compared with a numerical value detected through sensing, so that the monitoring accuracy is further guaranteed, and accurate and effective pressure-controlled injection is completed.

Ingestible devices can directly deliver therapeutic agents to desired tissue(s) of the GI tract of a subject, such as the submucosa, the mucosa, and / or the mucus layer of the GI tract, and methods of using the same. The ingestible devices can deliver therapeutic agents in a safe, effective, and reliable manner. The disclosure also provides pharmaceutical compositions for use in methods of treating a disease or condition.

A semi-automated veterinary medicine delivery device may sense whether and how much air may have been incorporated into a dose delivered to an animal. The device may also sense an incomplete injection in some cases and may cause a second dose to be administered to make up for the incomplete dose. The device may compare a position sensor on a syringe in combination with a current sensor on a motor attached to the syringe to detect any abnormalities. In the case of an improper dose, the device may alert the user and administer a second dose.

Optimized bio-synchronous drug delivery begins with establishing a bio-synchronous treatment protocol that incorporates individual temporal and innate biological characteristics into a pharmacological treatment plan. The bio-synchronous treatment protocol is thereafter initiated using bioactive agent delivery device. Bio-synchronous drug delivery includes continual collection of patient data such as physical, psychological, temporal and environmental characteristics. This data is analyzed so to not only determine an initial treatment protocol but to also determining whether modification to the ongoing bio-synchronous treatment protocol is required. And, responsive to determining a modification is required the system modifies the bio-synchronous treatment protocol and use of delivery device. These modifications and treatment protocols can include reactive and proactive psychological support supplied to the patient in a variety of formats.

The present invention provides an auxiliary device or system for a needleless syringe that uses the force of an elastic body to eject the injectable solution from the ampoule, and that can automatically perform the charging of the elastic body and the loading of the ampoule. [Solution] The auxiliary device 1 or system for the needleless syringe includes a holding unit 3 for holding the needleless syringe 10, an elastic body energy storage unit 5 for storing energy in the elastic body of the needleless syringe, an ampoule loading unit 6 for loading a pre-filled ampoule into the needleless syringe, a drive unit 7 for relatively moving the holding unit, and a control unit 8 for controlling the operation of the drive unit, and sequentially moves the needleless syringe to a position where the elastic body can be stored and to a position where the pre-filled ampoule can be loaded.

A minimally invasive body sculpting system and method is provided using a numbing component, a helium plasma component, and an NIL component. An NIL cannula of the NIL component is insertable into the body to remove the fat cell via nutational movement thereof and suction there through. Skin tightening is achieved through the subcutaneous exposure of the skin to helium plasma.

The present invention provides a quantitative needle-free syringe, comprising a medicine core assembly, a handle sleeve and a stepping piston assembly; an impact rod is provided on the rear end face of the syringe push rod, the stepping piston assembly is arranged at the rear end of the impact rod, and the stepping piston assembly pushes the impact rod to move forward; a non-return locking combination for locking and unlocking the impact rod and the handle sleeve is provided between the impact rod and the inner wall of the handle sleeve, the stepping piston assembly comprises a cylinder sleeve, a pneumatic piston and a main impact rod; a magnet and a magnet seat are fixed at the rear end of the pneumatic piston. The present invention has a reasonable structural design, can effectively stop and lock the impact rod, and realizes step-by-step excitation of the impact rod through the stepping piston assembly inside, the excitation is good, the pressure of the drug solution is stable, and the quantitative injection effect is excellent.

The present invention relates to a needle-free delivery solution for delivering drugs and vaccines applied in the field of human clinical care and animal health care, including a needle-free delivery device and components thereof, a system, and a related drug-instrument combination product. By means of the arrangement of multiple pores and the control of the flow rate of the jet flow of drugs and vaccines, the dispersion degree of drugs and vaccines in vivo, the number of pores, the pore size, and the distribution of the pores, the present invention can significantly improve the single-dose delivery amount of drugs and vaccines without damaging the skin, has a delivery efficiency far higher than that of existing needle-free injections, and can be applied to a wider range of application scenarios. The present invention can also accurately deliver drugs and vaccines to one or more target sites at different depths in the intracutaneous tissues, subcutaneous tissues, muscles, or human organs and enhance the dispersion effect at the target sites. The present invention can also precisely control the three-dimensional dispersion degree of drugs and vaccines at the target sites, and particularly, control and regulate the dispersion volume, the dispersion range, and the dispersion center position of drugs and vaccines at the target sites, thereby greatly improving the contact effect of drugs and vaccines with the in-vivo tissues and the bioavailability of drugs and vaccines. The needle-free delivery solution of the present invention exhibits a significantly improved drug absorption effect, effectiveness, and a significantly enhanced vaccine response effect in drug-instrument combination use with a feline triple vaccine, a human hepatitis B vaccine, a human pneumonia vaccine, a human tumor vaccine, and semaglutide, and especially after the vaccine is injected at an amount of 60% of a standard dose, the average antibody titer of the vaccine is 1.1 or more times that of a needle injection at a 100% standard dose, and 60 days after the second dose of the vaccine is injected, the average antibody titer can reach up to 6.3 or more times that of the average antibody titer of the needle injection. Therefore, a novel needle-free delivery solution featuring high efficiency, precision, and excellent bioavailability is provided for drug and vaccine delivery. This invention relates to a needle-free jet technology for the delivery of drugs and vaccines in the field of human and animal health,including needle-free delivery devices and their components,systems,and related drug-device combination products.By changing nozzle settings such as the number of pores,the size of pores,and the distribution of pores,the invention controls the jet rate and the dispersion of drugs and vaccines in the body,therefore achieves better efficiency compared to the traditional needle-based delivery method,and significantly increases quantities deliverable in a single dose without damaging the skin.The invention can accurately deliver drugs and vaccines to target depths in the skin,subcutis,muscle,or organs with enhanced dispersion of drugs and vaccines at the target depth.The invention can also accurately control the three-dimensional dispersion of drugs and vaccines at the target position.Through controlling and regulating the dispersion volume,dispersion area,and dispersion epicenter,the invention greatly improves the bioavailability of drugs and vaccines in the body.The needle-free jet delivery solution of this invention has been used in delivering multivalent cat vaccines,GLP-1 drugs,human hepatitis B vaccines,and human cancer vaccines in animal models.The drug-device combination of a polypeptide vaccine with the device shows significantly improved drug absorption and immunogenicity.For the commercially available polyvalent cat vaccine from Zoetis,60％of the standard dose was combined with the needle-free jet device,generating 1.1 times the average antibody titer of the standard dose using traditional needle-based injections.When a standard dose was combined with the needle-free jet device,the average antibody titer 60 days after the second dose of the vaccine reached up to 6.3 times the average antibody titer for the standard dose using traditional needle-based injection.The invention provides a new needle-free jet delivery solution with high efficacy,accuracy,and bioavailability for drugs and vaccines.

A disinfection tip is described for disinfecting a threaded connector of a syringe. The disinfection tip includes a cylindrical outer housing, a substantially cylindrical inner housing extending from a distal wall of the outer housing, a distal chamber defined by the outer sidewall of the inner housing, the inner wall of the outer housing and the distal wall of the outer housing, the distal chamber being in fluid communication with the cavity, the distal chamber retaining a disinfectant or antimicrobial agent when the disinfection tip is disposed within an outer wall of the luer connector of the syringe and, at least one jet orifice radially disposed on the inner rim in fluid communication with the distal chamber allowing for fluid to pass from the distal chamber through the jet orifice directing the disinfectant or antimicrobial agent towards a center of the outer housing when the disinfection tip is further inserted into the luer connector of the syringe, the insertion of the disinfection tip causing the volume of the distal chamber to reduce and expel disinfectant or antimicrobial agent through the at least one jet orifice.

The utility model relates to a needleless injector device capable of preventing injection shaking and conducting injection in batches, which belongs to the field of needleless injectors and comprises a reset motor, a reset screw rod, a reset block, a sliding block, a trigger, a sliding block positioning groove, a driving hammer, a driving hammer spring, an injection motor, an injection screw rod, a machine frame and a sliding sleeve. The reset screw is in threaded fit with a reset block, one face of the output end of the reset motor is installed on one side of the rack, the sliding block is located in the rack, the sliding block positioning groove is formed in the end of one side of the sliding block, the trigger is installed on the rack, the sliding sleeve is installed in the rack, the driving hammer is installed in the rack, and the head of the driving hammer is installed in the sliding sleeve in a sliding mode. The driving hammer spring is installed at the tail of the driving hammer, the injection motor is fixed in the rack, the output end of the injection motor is connected with the injection screw rod, and by arranging the pushing motor and the injection screw rod, the problems that multiple times of injection cannot be achieved, and medicine leakage or injection position deviation is caused by shaking during injection are solved.

The invention relates to an electromagnetic needleless injector based on a series excited motor, which comprises a cavity structure with an injector and a circuit main body structure integrated in a portable box body, and the circuit main body structure is electrically connected with a motor and a monitoring assembly in the cavity structure through a cable and is used for intelligently controlling the motor; the circuit main body structure comprises an MCU, a motor driving circuit, an energy storage module, a surge current suppression circuit and a communication module. The motor driving circuit isolates a control signal of the MCU from a high-voltage side MOS tube, and converts a control signal of a low-voltage side into a driving voltage of the motor; the energy storage module provides instantaneous large current during injection for a motor corresponding to the motor driving circuit; the surge current suppression circuit is used for suppressing surge current by adopting a two-stage charging mode when the circuit main body structure is started; and the MCU interacts with a cloud through the communication module and is used for issuing a control signal matched with an instruction to the motor driving circuit according to the instruction issued by the cloud so as to realize accurate control of the range of the motor.

The invention discloses a pressure-adjustable needleless injector based on double springs, and belongs to the technical field of needleless injectors.The technical scheme is that the pressure-adjustable needleless injector comprises an injection head shell, an injection cavity is formed in the injection head shell, and an open hole communicating the outside with the injection cavity is formed in the front end of the injection head shell; an injection push rod extending into the injection cavity is arranged at the rear end of the injection head shell; a transmission assembly is arranged between the driving mechanism and the injection push rod, the transmission assembly comprises a first barrel and a second barrel which are parallel to each other, transmission push rods are arranged in the first barrel and the second barrel in a sliding mode, the two transmission push rods are sleeved with percussion springs, and the two percussion springs are consistent in parameter but different in initial compression amount; the switching connection between the two transmission push rods and the injection push rod is realized by the two transmission push rods through a detachable switching piece; switching connection between the two transmission push rods and the driving mechanism is achieved through detachable connecting pieces. The pressure-adjustable needleless injector has the beneficial effect that the pressure-adjustable needleless injector based on the double springs is provided.

A needleless injector includes an injector assembly including a container that contains an injection target substance and a driver that has a mechanism that pressurizes the injection target substance to cause the injection target substance to be ejected from a nozzle formed at a top end of the container, a housing in which the injector assembly is fitted, a sensor that detects a pressing force when the nozzle is pressed against an injection target region, and a control circuit that acquires the pressing force detected by the sensor and, when the pressing force reaches a first prescribed value or more, makes a first determination that the driver is operable.

The utility model provides a needleless injector main body and a needleless injector. The needleless injector body includes: a base; the lens is arranged on the side surface of the base; an upper cover mounted on a side surface of the base and provided with a lens receiving hole to receive and expose the lens; wherein the lens comprises a main body and an installation base which is arranged below the main body and extends outwards in the radial direction to exceed the main body, the upper cover comprises a fixing edge which protrudes downwards from the lens containing hole, and when the upper cover is installed on the base, the fixing edge abuts against the installation base.

Injection systems comprising a powered injector and one or more hazardous agents are disclosed.

A device for applying fluid is provided, comprising: a cylinder (13); a piston (26) movable within the cylinder (13) between a front end position and a rear end position and connected to a piston rod (25); and a tensioning device (S) connected to the piston rod (25); wherein the tensioning device (S) has a ramp (42) rotatable by a motor (51) and a ramp path (41) extending along a helical line; wherein the tensioning device (S) further comprises a roller (40) contacting the ramp path (41) and rotatably mounted in a driver (31) connected to the piston rod (25), such that when the ramp (42) rotates in a first rotation direction (52), the ramp path (41) travels below the rotating roller (40); wherein a dose setting device (36) is provided, comprising a spacer (70) and a moving unit, wherein when the moving unit... When the plug (26) is in its rear end position, the moving unit can move the spacer (70) from the neutral position where the spacer (70) is not located between the driver (31) and the cylinder (13) into the working position between the driver (31) and the cylinder (13), such that the driver (31) is stopped by the spacer (70) after the roller (40) passes through the transition area (46), thereby resulting in a shorter piston stroke during the movement of the piston (26) toward the open distribution end compared to when the spacer (70) is in its neutral position; wherein the spacer (70) has a through hole (140) in which a spindle (143) having a spindle thread (142) is guided, wherein the spacer (70) has a pin (141) protruding into the spindle thread (142), and wherein the spindle thread (142) is inserted into an annular groove (144, 145) at at least one of its two ends.