206results about "Jet injection syringes" patented technology

A pre-filled dual-chamber medical agent delivery system assembled and configured to allow delivery of a single dose of a combined therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular design consisting of separately constructed components cooperatively arranged and coupled to one another, such as to facilitate delivery of a reconstituted lyophilized agent to a patient.

An injector including: a housing, a cap detachably coupled to the housing, a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly including a trigger engagement member, an energy source associated with the ram for powering the ram to expel medicament from the medicament container, a trigger member disposed about an axis, the trigger member moveable between a pre-firing configuration and a firing configuration, wherein medicament is expelled from the medicament container when the trigger member is in the firing configuration, a needle guard moveably coupled to the housing, the needle guard movable between a storage position and a pre-injection position, wherein the needle guard moves from the storage position to the pre-injection position as the cap is detached from the housing.

Optimized bio-synchronous drug delivery begins with establishing a bio-synchronous treatment protocol that incorporates individual temporal and innate biological characteristics into a pharmacological treatment plan. The bio-synchronous treatment protocol is thereafter initiated using bioactive agent delivery device. Bio-synchronous drug delivery includes continual collection of patient data such as physical, psychological, temporal and environmental characteristics. This data is analyzed so to not only determine an initial treatment protocol but to also determining whether modification to the ongoing bio-synchronous treatment protocol is required. And, responsive to determining a modification is required the system modifies the bio-synchronous treatment protocol and use of delivery device. These modifications and treatment protocols can include reactive and proactive psychological support supplied to the patient in a variety of formats.

The present invention provides an auxiliary device or system for a needleless syringe that uses the force of an elastic body to eject the injectable solution from the ampoule, and that can automatically perform the charging of the elastic body and the loading of the ampoule. [Solution] The auxiliary device 1 or system for the needleless syringe includes a holding unit 3 for holding the needleless syringe 10, an elastic body energy storage unit 5 for storing energy in the elastic body of the needleless syringe, an ampoule loading unit 6 for loading a pre-filled ampoule into the needleless syringe, a drive unit 7 for relatively moving the holding unit, and a control unit 8 for controlling the operation of the drive unit, and sequentially moves the needleless syringe to a position where the elastic body can be stored and to a position where the pre-filled ampoule can be loaded.

The utility model relates to a needleless injector device capable of preventing injection shaking and conducting injection in batches, which belongs to the field of needleless injectors and comprises a reset motor, a reset screw rod, a reset block, a sliding block, a trigger, a sliding block positioning groove, a driving hammer, a driving hammer spring, an injection motor, an injection screw rod, a machine frame and a sliding sleeve. The reset screw is in threaded fit with a reset block, one face of the output end of the reset motor is installed on one side of the rack, the sliding block is located in the rack, the sliding block positioning groove is formed in the end of one side of the sliding block, the trigger is installed on the rack, the sliding sleeve is installed in the rack, the driving hammer is installed in the rack, and the head of the driving hammer is installed in the sliding sleeve in a sliding mode. The driving hammer spring is installed at the tail of the driving hammer, the injection motor is fixed in the rack, the output end of the injection motor is connected with the injection screw rod, and by arranging the pushing motor and the injection screw rod, the problems that multiple times of injection cannot be achieved, and medicine leakage or injection position deviation is caused by shaking during injection are solved.

The invention relates to an electromagnetic needleless injector based on a series excited motor, which comprises a cavity structure with an injector and a circuit main body structure integrated in a portable box body, and the circuit main body structure is electrically connected with a motor and a monitoring assembly in the cavity structure through a cable and is used for intelligently controlling the motor; the circuit main body structure comprises an MCU, a motor driving circuit, an energy storage module, a surge current suppression circuit and a communication module. The motor driving circuit isolates a control signal of the MCU from a high-voltage side MOS tube, and converts a control signal of a low-voltage side into a driving voltage of the motor; the energy storage module provides instantaneous large current during injection for a motor corresponding to the motor driving circuit; the surge current suppression circuit is used for suppressing surge current by adopting a two-stage charging mode when the circuit main body structure is started; and the MCU interacts with a cloud through the communication module and is used for issuing a control signal matched with an instruction to the motor driving circuit according to the instruction issued by the cloud so as to realize accurate control of the range of the motor.

The invention discloses a pressure-adjustable needleless injector based on double springs, and belongs to the technical field of needleless injectors.The technical scheme is that the pressure-adjustable needleless injector comprises an injection head shell, an injection cavity is formed in the injection head shell, and an open hole communicating the outside with the injection cavity is formed in the front end of the injection head shell; an injection push rod extending into the injection cavity is arranged at the rear end of the injection head shell; a transmission assembly is arranged between the driving mechanism and the injection push rod, the transmission assembly comprises a first barrel and a second barrel which are parallel to each other, transmission push rods are arranged in the first barrel and the second barrel in a sliding mode, the two transmission push rods are sleeved with percussion springs, and the two percussion springs are consistent in parameter but different in initial compression amount; the switching connection between the two transmission push rods and the injection push rod is realized by the two transmission push rods through a detachable switching piece; switching connection between the two transmission push rods and the driving mechanism is achieved through detachable connecting pieces. The pressure-adjustable needleless injector has the beneficial effect that the pressure-adjustable needleless injector based on the double springs is provided.

A needleless injector includes an injector assembly including a container that contains an injection target substance and a driver that has a mechanism that pressurizes the injection target substance to cause the injection target substance to be ejected from a nozzle formed at a top end of the container, a housing in which the injector assembly is fitted, a sensor that detects a pressing force when the nozzle is pressed against an injection target region, and a control circuit that acquires the pressing force detected by the sensor and, when the pressing force reaches a first prescribed value or more, makes a first determination that the driver is operable.

The utility model provides a needleless injector main body and a needleless injector. The needleless injector body includes: a base; the lens is arranged on the side surface of the base; an upper cover mounted on a side surface of the base and provided with a lens receiving hole to receive and expose the lens; wherein the lens comprises a main body and an installation base which is arranged below the main body and extends outwards in the radial direction to exceed the main body, the upper cover comprises a fixing edge which protrudes downwards from the lens containing hole, and when the upper cover is installed on the base, the fixing edge abuts against the installation base.

A device for applying fluid is provided, comprising: a cylinder (13); a piston (26) movable within the cylinder (13) between a front end position and a rear end position and connected to a piston rod (25); and a tensioning device (S) connected to the piston rod (25); wherein the tensioning device (S) has a ramp (42) rotatable by a motor (51) and a ramp path (41) extending along a helical line; wherein the tensioning device (S) further comprises a roller (40) contacting the ramp path (41) and rotatably mounted in a driver (31) connected to the piston rod (25), such that when the ramp (42) rotates in a first rotation direction (52), the ramp path (41) travels below the rotating roller (40); wherein a dose setting device (36) is provided, comprising a spacer (70) and a moving unit, wherein when the moving unit... When the plug (26) is in its rear end position, the moving unit can move the spacer (70) from the neutral position where the spacer (70) is not located between the driver (31) and the cylinder (13) into the working position between the driver (31) and the cylinder (13), such that the driver (31) is stopped by the spacer (70) after the roller (40) passes through the transition area (46), thereby resulting in a shorter piston stroke during the movement of the piston (26) toward the open distribution end compared to when the spacer (70) is in its neutral position; wherein the spacer (70) has a through hole (140) in which a spindle (143) having a spindle thread (142) is guided, wherein the spacer (70) has a pin (141) protruding into the spindle thread (142), and wherein the spindle thread (142) is inserted into an annular groove (144, 145) at at least one of its two ends.

Systems and methods for treating and / or preventing metabolic disorders and / or other medical conditions in patients (e.g., felines) are described, by administering a liquid pharmaceutical composition, preferably containing one or more SGLT-2 inhibitor compounds, to the patient via a delivery system including a syringe. The syringe is characterized by facilitating the simple, safe, and effective dosage of small volume measurements of the liquid pharmaceutical composition to the patient during administration.

An intravitreal drug delivery tool (50) for positioning a needleless syringe for injecting a substance to be injected into the vitreous body of an eyeball without passing through an injection needle, the intravitreal drug delivery tool (50) being provided with: a guide (54) at least a part of which is formed in a shape corresponding to the outer edge of the cornea in the eyeball; and a positioning part (51) that is connected to the guide (54) and the needleless syringe, and that positions the needleless syringe when the guide (54) is disposed so as to be aligned with the outer edge of the cornea. The positioning unit (51) positions an injection port (77) from which the injection target substance is injected in the needleless injector at a position separated from the outer edge of the cornea toward the rear of the eyeball by a predetermined distance.

The present invention relates to a container (1) pre-filled or pre-fillable with one or more substances, such as medical fluids, the container comprising: a compressible actuated compartment (2) for containing the one or more substances; a dispensing compartment (3) comprising a first portion (31) and a second portion (32), the first portion being equipped with at least one dispensing member (311, 312, 314) for the one or more substances, wherein the second portion (32) of the dispensing compartment (3) and the actuated compartment (2) are hydrodynamically connected; and an actuator element (4) disposed within the container (1). The invention also relates to a method for dispensing at least one substance through the container (1), and a method for manufacturing the container (1).

The needle-free injector includes a dose setting device. The needle-free injector includes a hammer housing, a main spring positioned within the hammer housing, and a hammer assembly that engages with the main spring. The hammer assembly can include a hammer sleeve and a hammer that engages with the hammer sleeve, where engagement between the hammer sleeve and the hammer results in changing the forward or rearward position of the hammer relative to the hammer sleeve to select one injection dose from two or more available injection doses. Further embodiments include methods of varying or setting the dose delivered by the needle-free injector.

An elastic membrane for transmitting driving pressure of a needleless syringe, and the needleless syringe using same are disclosed. The elastic membrane (500) for transmitting pressure comprises: a body (510) which has elasticity, and which is provided between a driving chamber (402) and a driven chamber (202) so as to partition the driving chamber (402) from the driven chamber (202) in a sealed state; a driven protrusion part (520) in which a pressure-side cavity (522) opened to the driving chamber (402) is formed, and which protrudes from the central portion of the body (510) toward the driven chamber (202); and a driving protrusion part (530) which is spaced a predetermined distance from the edge of the body (510) and which protrudes toward the driving chamber (402), wherein, when a pressure (F) is applied from the driving chamber (402) such that the driving protrusion part (530) is pressed toward the driven chamber (202), the edge of the body (510) facing the driven chamber (202) becomes a hinge point (H), and thus the driven protrusion part (520) transmits the pressure while deformed toward the driven chamber (202).

A method of manufacturing an on-skin wearable device includes assembling electronic circuitry into an interior volume of a housing, the electronic circuitry configured to detect a signal generated by an electrochemical reaction under a subject's skin at a working electrode of an analyte sensor, wirelessly transmitting data derived from the detected signal to the outside of the housing for processing and / or display by a separate device; after the electronic circuitry is assembled into the interior volume of the housing, the proximal portion of the analyte sensor is attached to an external electrical interface coupled to the electronic circuitry such that the electronic circuitry is connected to the analyte sensor to receive a signal from the analyte sensor without opening the housing, the external electrical interface is formed in a recess in an external bottom surface of the housing, the external bottom surface being configured to directly contact a patch for coupling the housing to a subject's skin; a curable liquid is dispensed into the recess to seal the attachment of the proximal end portion of the analyte sensor to the external electrical interface.

The utility model provides a needleless injector main body and a needleless injector. The needleless injector body includes a locking mechanism for the injection actuator, the locking mechanism including: a pressing member provided on a side of the base; the blocking component comprises at least one vertical arm, and each vertical arm comprises a groove; the pivot component is arranged between the pressing component and the blocking component and comprises a pivot shaft and a first pivot arm and a second pivot arm which extend on the two sides of the pivot shaft, the first pivot arm is connected with the pressing component, the second pivot arm is connected with the blocking component, the injection actuator comprises at least one stop protrusion, and in the locking state, the stop protrusion is connected with the pressing component. During unlocking, the pressing component is pressed to drive the first pivoting arm to move downwards, the second pivoting arm moves upwards and drives the blocking component to move upwards, so that the grooves are aligned with the corresponding locking protrusions, and the corresponding locking protrusions are allowed to pass through. Thereby allowing the injection actuator to move from the non-actuated position to the actuated position.

A jet injector that includes a prefilled syringe. The syringe includes a fluid chamber that contains a medicament. The syringe also has an injection-assisting needle, and a plunger is movable within the fluid chamber. A housing is configured for allowing insertion of the needle to a penetration depth. An energy source is configured for biasing the plunger to produce an injecting pressure in the medicament in the fluid chamber of between about 80 and 1000 p.s.i. to jet inject the medicament from the fluid chamber through the needle to an injection site.

The present invention relates to an apparatus for administering a drug fluid, comprising: a cylinder (16, 116) having an open dispensing end (17); a piston (36) movable between a front end position and a rear end position in the cylinder (16, 116) and connected to a piston rod (35) which protrudes in a first direction beyond the rear end of the cylinder (16, 116) opposite to the open dispensing end (17) and is guided in a receiving block (10); a check valve (18) closing the open dispensing end (17); and a tensioning device (S) connected to the piston rod (35, 135) and disposed in the receiving block (10). When the piston (36) is in the front position, the tensioning device (S) can move the piston rod (35, 135) in a first direction during tensioning until the piston (36) is in the rear position, thereby filling the cylinder (16, 116) with the fluid to be administered and pre-tensioning the piston rod (35, 135) toward the open dispensing end (17). When the piston (36) is in its rear position, the tensioning device (S) can release the piston rod (35, 135) during dispensing, such that based on the applied pretension, the piston (36) moves in the opposite direction to the first direction until its front position, and thus the fluid in the cylinder (16, 116) is dispensed for administration through the check valve (18), wherein the cylinder (16, 116) together with the check valve (18) is designed as a replaceable front assembly (13, 14) which is detachably connected to the receiving block (10).

To provide a technology for injecting at least an injection object substance intracutaneously.SOLUTION: A device assembly for needleless syringe intracutaneously injects an injection object substance not via an injection needle, in which an energy value of gas generated when an igniter and a gas generating agent the device assembly are combusted, is within a prescribed range.SELECTED DRAWING: Figure 1

The present invention provides a method for determining a characteristic of a target area (15) of a material (10), the target area (15) being within a range of 100 μm 2 ~100mm 2 and the method comprises an exposure step comprising providing a liquid jet (20) to the target area (15), the liquid jet (20) having a jet speed selected from the range of 2 to 150 m / s, a measurement step comprising detecting deformations (16) of the material in the target area (15) and providing a related signal, and an analysis step comprising determining a characteristic of the target area (15) based on the related signal.

The utility model provides a needleless injector main body and a needleless injector. The needleless injector body includes a locking mechanism for the injection actuator, the locking mechanism being configured to lock the injection actuator in a non-actuated position in a locked state and to allow the injection actuator to move from the non-actuated position to an actuated position in an unlocked state, the locking mechanism including: a pressing member provided on a side of the base; the blocking component is arranged below one end of the pressing component and comprises at least one vertical arm, each vertical arm comprises a groove, the injection actuator comprises at least one stop protrusion, in the locking state, the grooves and the corresponding stop protrusions are staggered, in the unlocking state, the pressing component is pressed, the pressing component drives the blocking component to move downwards, and in the locking state, the blocking component drives the injection actuator to move downwards. The groove is aligned with the corresponding stop protrusion and allows the corresponding stop protrusion to pass through, so that the injection actuator is allowed to move from the non-actuating position to the actuating position.

The invention discloses a reversible multi-nozzle needleless injection ampoule with a turbulent flow mixing function, and belongs to the technical field of medical instruments. Due to the design of the integrally-formed nozzle base, all dynamic sealing interfaces which may fail under high pressure are eliminated, so that the pressure resistance of the ampoule is greatly improved, and the service life of the ampoule is greatly prolonged; according to intelligent switching of the injection modes, a user can switch between the deep precise injection mode and the superficial broad-spectrum coverage mode through simple rotating operation, unprecedented clinical adaptability is given to the ampoule, clear tactile / auditory feedback is achieved in the switching process, the clinical adaptability is high, and operation is convenient and fast. The multifunctional injector integrates the functions of injection mode switching, liquid medicine mixing and front-end medicine taking, and the clinical adaptability and operation convenience are improved.

A system and method for automatically delivering a substance to an animal or fish including a positioning system that positions each animal singularly and a sensor that detects the location of a predetermined targeted area on the animal. The system further includes a delivery device for delivering a substance to the targeted area. The position of the delivery device may be adjustable. The delivery device is in communication with the sensor. The delivery device adjusts its position in response to the data received from the sensor and delivers a substance to the targeted area.

The invention relates to a device for administering a fluid, comprising a barrel (13), a plunger (26) which can be moved in the barrel (13) between a front and rear end position and which is connected to a plunger rod (25), and a clamping device (S) which is connected to the plunger rod (25), said clamping device (S) having a ramp (42) which can be rotated by means of a motor (51) and comprises a ramp track (41) extending along a helical line. The clamping device (S) additionally has a roller (40) which contacts the ramp track (41) and is rotatably mounted in a driver (31) connected to the plunger rod (25) such that when the ramp (42) is rotated along a first rotational direction (52), the ramp track (41) passes under the roller (40), which is thereby rotating. A metering setting device (36) is provided which comprises a spacer (70) and a movement unit, wherein the movement unit can move the spacer (70) from a neutral position, in which the spacer (70) is not positioned between the driver (31) and the barrel (13), into an active position, in which the spacer is positioned between the driver (31) and the barrel (13), when the plunger (26) is in the rear end position so that the driver (31) is stopped by the spacer (70) after the roller (40) passes over the transition region (46) and thus the plunger stroke is shorter during a movement of the plunger (26) towards the open dispensing end in comparison to when the spacer (70) is in the neutral position. The spacer (70) has a through-bore (140) in which a spindle (143) with a spindle thread (142) is guided, and the spacer (70) has a pin (141) which engages into the spindle thread (142), said spindle thread (142) opening into an annular groove (144, 145) at at least one of the two ends of the spindle thread. Figure for the abstract: Fig. 27D

A device for administering a fluid can include a cylinder, a piston connected to a piston rod, and a tensioning device connected to the piston rod. The tensioning device includes a ramp which is rotatable via a motor, a ramp track, and a roller which is in contact with the ramp track and which is mounted rotatably in a driver. The driver can be connected to the piston rod via a joint. In a tensioning procedure, the ramp track is rotated such that the roller runs on the region of inclination as far as the second plateau and the piston is thereby moved to its rear end position. In a dispensing procedure, the ramp track is rotated until the roller runs over a transfer region and, on account of the tensioning, is accelerated toward the first plateau and, as a result, the piston is moved toward the an dispensing end.

The invention belongs to the field of injectors, and particularly relates to a multi-hole needleless injector driven by a same-air-source double-channel Laval nozzle, which comprises a compressed air source and a control valve, the two Laval nozzles are arranged in parallel and have different structural parameters, and inlets of the two Laval nozzles are both communicated with the compressed air source; the pneumatic cavities are respectively communicated with outlets of the two Laval spray pipes; the pistons are arranged in the cavities; the liquid medicine storage chamber is connected with the piston of the transmission assembly; the injection spray head assembly is connected with an outlet of the liquid medicine storage chamber and comprises a central main spray hole and a plurality of peripheral auxiliary spray holes arranged around the central main spray hole, the central main spray hole corresponds to the piston driven by one path of high-pressure air flow, and the peripheral auxiliary spray holes correspond to the piston driven by the other path of low-pressure air flow. Under the condition that a needle head is not needed, the subcutaneous distribution uniformity of liquid medicine is remarkably improved, the injection precision is improved, and the tissue damage risk is reduced.

Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and / or distribution of density (or mass) which, for example, enables the self- righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and / or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject) such as a liquid pharmaceutical agent. In some cases, upon contact of the tissue with the tissue engaging surface of the article, the self-righting article may be configured to release one or more tissue interfacing components. In some cases, the tissue interfacing component is associated with a self- actuating component. For example, the self-righting article may comprise a self-actuating component configured, upon exposure to a fluid, to release the tissue interfacing component from the self-righting article.