31results about "Jet injection syringes" patented technology

Optimized bio-synchronous drug delivery begins with establishing a bio-synchronous treatment protocol that incorporates individual temporal and innate biological characteristics into a pharmacological treatment plan. The bio-synchronous treatment protocol is thereafter initiated using bioactive agent delivery device. Bio-synchronous drug delivery includes continual collection of patient data such as physical, psychological, temporal and environmental characteristics. This data is analyzed so to not only determine an initial treatment protocol but to also determining whether modification to the ongoing bio-synchronous treatment protocol is required. And, responsive to determining a modification is required the system modifies the bio-synchronous treatment protocol and use of delivery device. These modifications and treatment protocols can include reactive and proactive psychological support supplied to the patient in a variety of formats.

A needleless injector includes an injector assembly including a container that contains an injection target substance and a driver that has a mechanism that pressurizes the injection target substance to cause the injection target substance to be ejected from a nozzle formed at a top end of the container, a housing in which the injector assembly is fitted, a sensor that detects a pressing force when the nozzle is pressed against an injection target region, and a control circuit that acquires the pressing force detected by the sensor and, when the pressing force reaches a first prescribed value or more, makes a first determination that the driver is operable.

The present invention relates to a container (1) pre-filled or pre-fillable with one or more substances, such as medical fluids, the container comprising: a compressible actuated compartment (2) for containing the one or more substances; a dispensing compartment (3) comprising a first portion (31) and a second portion (32), the first portion being equipped with at least one dispensing member (311, 312, 314) for the one or more substances, wherein the second portion (32) of the dispensing compartment (3) and the actuated compartment (2) are hydrodynamically connected; and an actuator element (4) disposed within the container (1). The invention also relates to a method for dispensing at least one substance through the container (1), and a method for manufacturing the container (1).

An elastic membrane for transmitting driving pressure of a needleless syringe, and the needleless syringe using same are disclosed. The elastic membrane (500) for transmitting pressure comprises: a body (510) which has elasticity, and which is provided between a driving chamber (402) and a driven chamber (202) so as to partition the driving chamber (402) from the driven chamber (202) in a sealed state; a driven protrusion part (520) in which a pressure-side cavity (522) opened to the driving chamber (402) is formed, and which protrudes from the central portion of the body (510) toward the driven chamber (202); and a driving protrusion part (530) which is spaced a predetermined distance from the edge of the body (510) and which protrudes toward the driving chamber (402), wherein, when a pressure (F) is applied from the driving chamber (402) such that the driving protrusion part (530) is pressed toward the driven chamber (202), the edge of the body (510) facing the driven chamber (202) becomes a hinge point (H), and thus the driven protrusion part (520) transmits the pressure while deformed toward the driven chamber (202).

The present invention relates to an apparatus for administering a drug fluid, comprising: a cylinder (16, 116) having an open dispensing end (17); a piston (36) movable between a front end position and a rear end position in the cylinder (16, 116) and connected to a piston rod (35) which protrudes in a first direction beyond the rear end of the cylinder (16, 116) opposite to the open dispensing end (17) and is guided in a receiving block (10); a check valve (18) closing the open dispensing end (17); and a tensioning device (S) connected to the piston rod (35, 135) and disposed in the receiving block (10). When the piston (36) is in the front position, the tensioning device (S) can move the piston rod (35, 135) in a first direction during tensioning until the piston (36) is in the rear position, thereby filling the cylinder (16, 116) with the fluid to be administered and pre-tensioning the piston rod (35, 135) toward the open dispensing end (17). When the piston (36) is in its rear position, the tensioning device (S) can release the piston rod (35, 135) during dispensing, such that based on the applied pretension, the piston (36) moves in the opposite direction to the first direction until its front position, and thus the fluid in the cylinder (16, 116) is dispensed for administration through the check valve (18), wherein the cylinder (16, 116) together with the check valve (18) is designed as a replaceable front assembly (13, 14) which is detachably connected to the receiving block (10).

A system and method for automatically delivering a substance to an animal or fish including a positioning system that positions each animal singularly and a sensor that detects the location of a predetermined targeted area on the animal. The system further includes a delivery device for delivering a substance to the targeted area. The position of the delivery device may be adjustable. The delivery device is in communication with the sensor. The delivery device adjusts its position in response to the data received from the sensor and delivers a substance to the targeted area.

The present invention relates to polypeptide modulators of complement activity, including cyclic polypeptide modulators. Included are methods of utilizing such modulators as therapeutics.

A needle-free injector including dose setting apparatus. The needle-free injector includes a hammer housing, a mainspring positioned within the hammer housing, and a hammer assembly engaged with the mainspring. The hammer assembly may include a hammer sleeve and a hammer engaged with the hammer sleeve, where the engagement between the hammer sleeve and the hammer provides for a forward or rearward position of the hammer with respect to the hammer sleeve be changed to select an injection dose from two or more available injection doses. Additional embodiments include methods of varying or setting the dose delivered by a needle-free injector.

A system for atomizing and ejecting a formula including a tank, a nozzle fluidly connected to the tank including a Venturi tube and a tip, a cylinder with an outlet hole, the outlet hole fluidly connected to an inlet the Venturi tube, a piston arranged in the cylinder so as to be displaceable in the cylinder, a driving unit for the displacing of the piston in a direction in which a volume of an air intake space in the cylinder increases, an elastic member deformed according to the displacement of the piston and that stores an elastic energy while the piston is being displaced, where the driving unit includes an elastic energy release mechanism that releases the elastic energy, causing the piston to rush in and a vibration, and a dampener on the nozzle, positioned between the Venturi tube and the tip, where the dampener reduces the vibration.

The utility model provides a cap for needleless injection equipment and a needleless injection component, the needleless injection equipment comprises an injector main body and an injection head, and the injection head is constructed to be capable of being installed on the injector main body for medicine suction and injection. The cap has a proximal end and a distal end, wherein the cap includes a body member and a pressing member. The main body piece is arranged at the far end of the cap and can be arranged on the syringe main body in a sleeving mode. The pressing piece is arranged at the near end of the cap and connected to the main body piece, the pressing piece comprises a sleeving part and a peripheral part arranged on the periphery of the sleeving part, the sleeving part is constructed to be capable of sleeving the injection head, an annular groove part is formed between the peripheral part and the sleeving part, and the peripheral part and the sleeving part are connected together through the groove part; an opening of the groove portion faces the proximal end of the cap. According to the scheme, the skin around the injection part can be automatically pinched up by the groove part when the needleless injection equipment performs injection operation, so that the stability during injection is improved.

Embodiments of the invention provided methods and systems for collagen remodelling of an area of skin of a subject using a collagen remodelling device. The method may comprise heating, by a heater unit of the device, a liquid to a temperature configured to cause micro burns to the skin of the subject when the liquid is in contact with the skin of the subject and injecting the liquid, using a needleless injection unit of the device, from a liquid reservoir of the device into the area of skin of the subject.

A syringe with an arc-shaped plunger handle that can be fitted both inside and outside the barrel. This ensures that the plunger is pushed straight, and, combined with the hinged plunger head, allows the handle to be folded outwards from the barrel, minimizing its volume. A rotating cap attached to the handle covers the dispensing end of the syringe, sealing the tip.

The application discloses an injector, which comprises a shell, a mounting channel extending in a first direction arranged at one end of the shell, an injection assembly arranged at a first end of the mounting channel, an energy storage assembly movably arranged in the first direction in the mounting channel, a first end of the energy storage assembly being adapted to be connected with the injection assembly to drive the injection assembly to inject or suck liquid, a second end of the energy storage assembly being provided with a first elastic member, the first elastic member being retractable in the first direction, a control assembly movably arranged between a first position and a second position in the shell, the control assembly being provided with a transmission part, in the case that the control assembly is in the first position, the transmission part is matched with the energy storage assembly to drive the energy storage assembly to compress the first elastic member in the first direction and make the injection assembly suck liquid, and in the case that the control assembly is in the second position, the transmission part is disengaged from the energy storage assembly, the first elastic member drives the energy storage assembly to make the injection assembly inject liquid.

For an applicator for needleless injection of an active medium (WM), which permits a high injection pressure and ensures a reliable and secure separation of the injectable active medium (WM) from the actuation of the device (1), an injection valve (20) is provided in the applicator (B) and a working medium (AM) with a working pressure (pA) can be applied at an inlet (27) of the injection valve, a pressure volume (21) is provided in the applicator (B), and the pressure volume (21) is filled with working medium (AM) at an initial pressure less than the working pressure (pA), the operational injection valve (20) is configured to inject into the pressure volume (21) a predetermined injection quantity of the working medium (AM) with an injection pressure (pE) between the working pressure (pA) and the initial pressure, and there is provided in the applicator (B) a movably arranged plunger (22), which at a first end has a plunger piston (26) that at least partially delimits the pressure volume (21), and which, with an opposite second end, bears on the pressure piston (25) such that the operational plunger (22) is movable in the direction of the pressure piston (25) in order to move the pressure piston (25) so as to deliver an active-medium pulse from at least nozzle opening (29)m, (FIG. 2).

The utility model provides needle-free injection equipment. The needleless injection device includes an operating portion disposed at a distal end of the needleless injection device and having an operating portion housing and an injection portion. The injection part is arranged at the near end of the needleless injection device and provided with an injection part shell, the injection part is connected to the operation part, and the near end of the injection part is provided with a first opening used for installing a medicine tube. Wherein the operating part is configured to be rotatably mounted to the injection part and can reciprocate relative to the injection part when the operating part rotates relative to the injection part, and the cross section of at least one part of the outer side wall of the operating part shell is in a non-circular shape, and / or the cross section of at least one part of the outer side wall of the operating part shell is in a non-circular shape. The cross section of at least one part of the outer side wall of the injection part shell is in a non-circular shape. According to the scheme, a user can conveniently carry out operations such as holding and screwing on the operation part or the injection part of the needleless injection equipment.

The invention concerns improvements in needle-free devices for the delivery of therapeutic and / or prophylactic agents, such as solid dose drugs, including vaccines. The needle-free devices disclosed herein comprises novel structural arrangements and modes of actuation and operation, resulting in enhanced functionality and benefits to the user and / or patient.

The utility model relates to medical instrument technical field discloses a needleless injector, including main part, needleless injection head and liquid outlet valve, the main part is equipped with transition chamber, liquid outlet chamber and power chamber, transition chamber is used for pre -filling liquid medicine, power chamber is coaxial with transition chamber, liquid outlet chamber is established, and the cross section area of transition chamber is less than the cross section area of power chamber, the needleless injection head is equipped with injection chamber, and the injection micropore that communicates injection chamber with outside, the one end of needleless injection head away from injection micropore stretches into liquid outlet chamber, and will liquid outlet valve and set up in liquid outlet chamber, liquid outlet valve includes first valve body and first valve core, the one end of first valve body near transition chamber is sealed with liquid outlet chamber arrangement, first valve body is equipped with first guide chamber, the outer periphery of first valve body is equipped with first through -hole, the outer periphery of first valve body and the inside wall of liquid outlet chamber have first gap, first gap and injection chamber, first through -hole are communicated, first valve core can reciprocate in first guide chamber, to make transition chamber and first through -hole communicate or disconnect. The needleless injector of the utility model is simple structure, and the processing cost is low, and the stable injection effect.

An intravitreal administration tool (50) is provided which positions a needleless injector that injects a substance to be injected into a vitreous body of an eyeball without using an injection needle. The intravitreal administration tool includes a guide (54), at least a part of which is formed in a shape corresponding to the outer edge of a cornea of the eyeball, and a positioning portion (51) that is connected to the guide (54) and the needleless injector and that positions an ejection port (77), of the needleless injector, from which the substance to be injected is ejected, at a position away from the outer edge of the cornea by a predetermined distance rearward of the eyeball when the guide (54) is disposed in alignment with the outer edge of the cornea.

We provide ingestible drug delivery devices. [Solution] A drug delivery device 100 for administration to a target may include a reservoir 110 containing an active pharmaceutical ingredient and a potential energy source. The drug delivery device may also include a trigger 112 operationally associated with the potential energy source. The trigger 112 may be configured to activate at a predetermined location within the target and deploy a spray of the active pharmaceutical ingredient into the tissue of an adjacent portion of the gastrointestinal tract. In some cases, the spray may be deployed into the tissue of the stomach and / or small intestine of the target. Furthermore, in some embodiments, the operating parameters of the spray may be selected so that the spray penetrates the tissue of the gastrointestinal tract and forms a depot of the active pharmaceutical ingredient that is disposed within the tissue.

The utility model provides a kind of needleless injector main body and needleless injector.The needleless injector main body includes the auxiliary medicine suction mechanism for storing bottle, auxiliary medicine suction mechanism is arranged between storage bottle and main push rod, and auxiliary medicine suction mechanism includes: auxiliary push member, configured to engage with the piston of storage bottle before medicine suction operation;Actuating spring is arranged between auxiliary push member and main push rod, wherein, before medicine suction operation, actuating spring is in compressed state, the piston of storage bottle remains stationary relative to main push rod, during medicine suction operation, the piston of storage bottle moves forward relative to main push rod, and auxiliary push member is pushed forward the piston of storage bottle under the action of actuating spring.

At a minimum, the following is provided. An injector capable of forming a space in a target is provided. The problem is solved by an injector for injecting a liquid and a gas into a target from an injector body without performing injection through a predetermined structure in a state in which the predetermined structure is inserted into the target, the injector including a storage to store the liquid and the gas, a nozzle in communication with the storage and including an ejection port for ejecting the liquid and gas toward the target, and a pressurizer to pressurize the liquid and gas stored in the storage to eject the liquid and gas from the ejection port toward the target when activated. The ratio of the volume of the gas to the total volume of the liquid and gas is more than 60 % and 80 % or less.

A system (10) for atomizing and ejecting a formula including a tank (100), a nozzle (910) fluidly connected to the tank (100) including a Venturi tube (200) and a tip (270), a cylinder (300) with an outlet hole (330), the outlet hole (330) fluidly connected to an inlet (232) the Venturi tube (200), a piston (400) arranged in the cylinder (300) so as to be displaceable in the cylinder (300), a driving unit (500) for the displacing of the piston (400) in a direction in which a volume of an air intake space in the cylinder (300) increases, an elastic member (600) deformed according to the displacement of the piston (400) and that stores an elastic energy while the piston (400) is being displaced, where the driving unit (500) includes an elastic energy release mechanism that releases the elastic energy, causing the piston (400) to rush in and a vibration, and a dampener (800) on the nozzle (910), positioned between the Venturi tube (200) and the tip (270), where the dampener (800) reduces the vibration.

Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

The application discloses an intelligent needleless injector, and particularly relates to the field of needleless injection technology, which comprises an outer shell, a support is arranged in the inner cavity of the outer shell, a motor seat is linearly and slidingly arranged in the inner cavity of the thick end of the support, a driving motor is arranged in the motor seat, an energy storage mechanism is driven at the output end of the driving motor, the energy storage mechanism is always abutted against a driving spring extending towards the driving motor, the other end of the driving spring is abutted against the inner cavity step of the support, and the driving spring is abutted against a pressure sensor at any end, a dose adjusting motor is fixedly arranged at the end of the energy storage mechanism close to the driving motor, a medicine taking mechanism is driven at the output end of the dose adjusting motor, a connecting rod of the medicine taking mechanism is connected with a push rod, a medicine storage cylinder is connected to the slender end of the support, and the end of the push rod away from the medicine taking mechanism is connected with a piston, even if the elasticity of the driving spring decreases after long-term use, the initial injection pressure can be accurately controlled, and the skin can be ensured to be punctured.

An injection device is provided for delivering a liquid medicament. The injection device includes a housing with a first chamber for storing a supply of the medicament. The first chamber and a second chamber are coupled within the housing. The second chamber is in fluid communication with the first chamber. The system also includes an outlet port for dispensing the medicament outside the housing. The outlet port is coupled to the housing and in fluid communication with one of the first and second chambers.

The present application provides a holding device for a storage container of a needleless injector, which can be switched between a locked state and an unlocked state, in the locked state, the holding device can prevent the storage container from being mounted to or removed from an injector body of the needleless injector; in the unlocked state, the holding device can allow the storage container to be mounted to or removed from the injector body, the holding device comprises: an operable part operated by an operator to switch the locked state and the unlocked state; a linkage mechanism switched between a first state and a second state in response to the operation of the operable part. The needleless injector comprising the holding device is also provided. According to the holding device and the needleless injector of the present application, the built-in medicine storage bottle can be freely mounted and taken out in the injector, and the built-in medicine storage bottle can be easily taken out or placed without using a separate tool, which provides convenience for the operator to use the needleless injector.

The present application relates to the technical field of medical devices, in particular to a kind of pneumatic needleless injector, it includes: shell;Liquid path component, including drug liquid pump cylinder, striker, first check valve, second check valve and jet head;Gas path component, including pneumatic piston and pilot two-position five-way electromagnetic valve;Circuit component, including power supply, trigger switch and anti-misoperation switch, trigger switch and anti-misoperation switch are connected in series, and are electrically connected with power supply and pilot two-position five-way electromagnetic valve;Handle component, including handle and handle seat;Solve the machining difficulty big, complex structure, heavy and the problem of operation jam of existing pneumatic continuous needleless injector.