73 results about "Wound surface" patented technology

The utility model relates to a kind of wound elastic dressing device, the wound elastic dressing device can complete the fixing of the fixed component itself, i. e. the fixed component itself can complete the fixing of the fixed component, so that the wound surface of the fixed component is driven to the wound surface of the fixed component, and the fixing process can be completed by the adhesion of the first magic tape and the second magic tape. In this way, the wound surface can be treated without being adhered to the skin, which eliminates the secondary damage to the wound surface during wound care, so that it can adapt to a larger wound surface. At the same time, since the fixing can be completed without being adhered to the skin, the formation of the adhesive surface with poor air permeability between the product and the skin is avoided, thereby avoiding discomfort on the adhesive surface and improving the use comfort of the product. In addition, different sizes of dressing components can be used for different wounds, which improves the application range of the product.

This utility model relates to the field of minimally invasive postoperative wound dressing technology, specifically a minimally invasive postoperative wound dressing with wound closure function. It includes an adhesive layer, release paper installed on both sides of the bottom of the adhesive layer, low-sensitivity adhesive tape evenly installed on both sides of the top of the adhesive layer, and a sterilization layer embedded in the middle of the adhesive layer. The improved minimally invasive postoperative wound dressing adds a first elastic band and a second elastic band. When the wound dressing is applied to the wound surface, the first and second elastic bands can be pulled to traction the sides of the adhesive layer, thereby effectively closing the wound, reducing the risk of wound dehiscence, and promoting rapid wound healing. An absorbent layer made of highly absorbent resin is also added, allowing the absorbent layer to quickly absorb tissue fluid exudated from the wound during the healing process, helping to reduce the risk of wound infection and thus promoting wound healing.

This invention belongs to the field of external application of traditional Chinese medicine preparations, specifically relating to a waterproof dressing for wound protection. It comprises plant charcoal, plant oil, and a traditional Chinese medicine ointment, wherein the plant charcoal, plant oil, and traditional Chinese medicine ointment are mixed and prepared into a paste in a weight ratio of (0.3-2.5):3:(0.5-2.7). The technical solution provided by this invention uses simple plant charcoal, plant oil, and traditional Chinese medicine ointment to form a stable protective layer on the wound surface using the wound's own exudate. Once fully cured, it does not peel off upon contact with water, greatly reducing the risk of infection. Furthermore, it allows for the easy addition of other traditional Chinese medicine ingredients to achieve other therapeutic purposes such as promoting healing and inhibiting bacteria.

The application comprises a bottom layer, a liquid absorption layer and an isolation layer which are sequentially arranged in a stacked mode, the bottom layer is provided with an inner surface facing the liquid absorption layer, an outer surface opposite to the inner surface and a plurality of through holes penetrating through the inner surface and the outer surface, and a plurality of micron-sized protrusions are arranged on the outer surface at intervals. The liquid absorption layer is a hydrophilic layer with super hydrophilicity, and the bottom layer and the isolation layer are hydrophobic layers. According to the application, a good healing environment can be provided, and the application is easy to strip from a wound surface.

This invention discloses a powder composition for the prevention and treatment of symblepharon (eyelid-eye-ball adhesion). The powder composition comprises a polymer material that cross-links with each other upon contact with an aqueous medium, forming a hydrogel isolation membrane in situ at the wound surface. This invention also discloses the application of the above-mentioned powder composition in the preparation of medicaments for the prevention and / or treatment of symblepharon. The powder composition provided by this invention, when applied to ocular surface wounds, rapidly forms a physical isolation layer in situ. This formed physical isolation layer exhibits good stability and can be gradually and gently degraded without the need for secondary surgical removal.

The application relates to the technical field of medical devices, and discloses a gynecological clinical medicine applying device, which comprises a medicine applicator body, a piston rod is slidably arranged in the medicine applicator body, a protective cover is movably sleeved at the bottom end of the medicine applicator body, an installation groove is formed in the top of the piston rod, a pressing rod is slidably arranged in the installation groove, a spring is fixedly arranged at the bottom end of the pressing rod and is limitingly and movably connected with the inner side wall of the installation groove, and an adjusting plate is limitingly and rotatably arranged at the top end of the pressing rod. The spring is stretched to store power, the pressing rod slides and impacts in the direction of the medicine powder under the action of the spring force, the piston rod is impacted to spray the medicine powder outward, a relatively stable medicine powder spraying area is achieved, the coverage of the medicine powder on a wound surface is improved, the probability that the wound healing time is prolonged due to the insufficient coverage of the medicine powder on the wound surface is reduced, and the medicine powder can play a maximum effect.

This invention relates to a urinary catheter for post-prostatectomy, comprising an outer sheath, a catheter disposed inside the outer sheath, and an expansion component disposed on the surface of the outer sheath. Compared with the prior art, this invention, through the protruding structure on the surface of the balloon, allows the doctor to achieve hemostasis on the wound after prostatectomy via the balloon. The protruding structure can closely fit the uneven interior of the wound after surgery, resulting in better hemostasis compared to the smooth balloon surface in the prior art. At the same time, since the interior of the protrusion is connected to the interior of the balloon, the expansion size of the protrusion during the balloon inflation phase can be affected by the unevenness of the wound surface, avoiding excessive pressure on the post-operative wound area. In addition, the design of multiple sub-protrusions can increase the contact area after the balloon is filled with water or air, resulting in better compression hemostasis.

This invention relates to hydrogels, specifically to a hydrogel for wound repair, its preparation method, and its applications. Through material design and optimization, this invention successfully prepared a multifunctional composite hydrogel system composed of N-isopropylacrylamide, gelatin, tannic acid, poly-L-lysine, and ferric chloride, and systematically investigated its physicochemical properties and biological functions. This hydrogel possesses a unique network structure, balancing mechanical properties and flexibility, and can dynamically adapt to the wound microenvironment and closely adhere to the wound surface. Tannic acid and Fe... 3+ Coordination and complexation enhance antioxidant properties, protecting against oxidative stress damage; poly-L-lysine and tannic acid synergistically endow it with highly effective broad-spectrum antibacterial properties, inhibiting the proliferation of Staphylococcus aureus and Escherichia coli; mouse experiments show that it can significantly accelerate the healing of full-thickness skin defects. This PGTPL composite hydrogel integrates multiple functions and has great potential for application in the treatment of infected wounds.

The present application relates to a kind of multifunctional medical fiber membrane and its preparation method and application, the multifunctional medical fiber membrane is with including poly high molecular material, material with anionic group, collagen and ε-polylysine in it Material is raw material, using the electrospun fiber membrane prepared by conjugated electrospinning technology.This medical fiber membrane has the advantages of electrospun membrane and self-assembly membrane simultaneously, close to the structure of extracellular matrix, can provide a large number of cell contact points, provide better microenvironment for cell adhesion, proliferation, physiological function;It contains collagen and ε-polylysine in composition, can make it have good hydrophilicity and antibacterial property, the addition of material with anionic group makes collagen and ε-polylysine more stably combined on fiber membrane, so that it slowly releases, while its own good characteristics make product can be directly attached in clinical use, more effectively induce cell growth and tissue regeneration, and then effectively promote the repair of wound surface.

This invention relates to a topical agent for preventing and treating poplar canker and its application method. The topical agent, by weight percentage, comprises the following ingredients: 0.1-0.2% pyraclostrobin; 1-3% wetting and dispersing agent; 0.2%-0.8% thickener; 2-4% antifreeze agent; 0.01%-0.3% micronutrient fertilizer; 0.1%-0.3% defoamer; and the balance being deionized water. Before application, first use a scraper to clean the ulcerated areas on the poplar branches and trunks, thoroughly scraping away the rotten tissue, extending 2-3 cm beyond the diseased area on both the upper and lower surfaces. Then, evenly and promptly apply the topical agent to the treated wound surface, cover it with breathable non-woven fabric, and then apply another layer of topical agent over the non-woven fabric, ensuring close adhesion to the branches and trunk. The topical agent of this invention is simple to use, highly effective, and can effectively control canker, reduce the impact on poplar growth, and achieve efficient prevention and treatment of poplar canker.

The application belongs to the technical field of biological medicine, and specifically discloses application of miR-184-3p in preparation of a medicine for improving repair of diabetes-related tissue damage. The miR-184-3p has a nucleotide sequence as shown in SEQ ID NO. 1. Research finds that miR-184-3p can regulate anti-inflammatory factors of a diabetes wound surface and play a role in wound repair, down-regulate expression of an inflammatory factor IFN-gamma, and up-regulate expression levels of anti-inflammatory cytokines IL-4 and IL-13. In particular, for regulating excessive inflammatory reactions of a diabetes wound surface and promoting wound healing, miR-184-3p can be used as an active ingredient to develop a diabetes wound anti-inflammatory or a medicine preparation for promoting repair of related tissue damage, and has a good application prospect.

This invention discloses a GelMA hydrogel-based repair gel for diabetic foot wounds and its preparation method, belonging to the field of biomedical polymer materials and wound repair technology. The repair gel, by weight, comprises GelMA, a photoinitiator, a composite antibacterial agent, embedded growth factors, sodium hyaluronate, an antioxidant, a mechanical modifier, and a pH buffer solvent. This invention constructs a five-pathway synergistic repair system of "antibacterial-antioxidant-anti-inflammatory-promoting angiogenesis-promoting epithelialization," solving the industry pain points of easy inactivation and lack of long-term sustained release of growth factors through liposome encapsulation technology. It can be rapidly photocured in situ on the wound surface, perfectly adapting to irregular foot wounds, and possesses excellent storage stability, light stability, biocompatibility, and controllable degradation. It can significantly improve the pathological microenvironment of diabetic foot wounds and accelerate wound healing.

The application discloses a hydrogel with antibacterial and hemostatic functions and a preparation method and application thereof. The composite hydrogel is mainly prepared by mixing polyvinyl alcohol (PVA), natural honey and a nano-silver solution. The preparation method comprises the following steps: firstly, a stable dispersed nano-silver base solution is prepared by using a high-molecular dispersant and a reducing agent, and dialysis purification is performed on the base solution; then, deionized water and PVA are added and heated and stirred until completely dissolved; after cooling, natural honey is added dropwise and uniformly mixed, and physical cross-linking molding is performed by using a freeze-thaw cycle technology after ultrasonic defoaming. The hydrogel can quickly absorb exudates on a wound surface and promote blood coagulation by using the strong and tough porous network of PVA, and can realize multiple synergistic antibacterial under a low-toxicity and safe concentration by combining the microscopic physical damage of nano-silver and the high-osmotic and slightly acidic environment of natural honey. The hydrogel preparation process is green and safe, no chemical cross-linking agent is left, and the hydrogel has excellent dynamic and non-invasive adhesion and long-acting moisturizing properties, and can be widely applied to rapid sealing, hemostasis and healing promotion treatment of complex infected wounds.

This invention provides a chitosan hemostatic material for rapid arterial hemostasis, its preparation process, and its applications, relating to the field of medical technology. The chitosan hemostatic material prepared by this invention can significantly shorten hemostasis time, maintain stable adhesion to the wound surface even under the impact of arterial blood flow, and is not easily detached, exhibiting strong wet adhesion and erosion resistance. The chitosan hemostatic material prepared by this invention not only improves the mechanical strength of the material but also provides more bioactive sites, activating intrinsic coagulation pathways and platelet aggregation, thereby improving hemostasis efficiency and showing significant advantages in emergency applications for arterial bleeding. The chitosan hemostatic material prepared by this invention combines rapid coagulation and stable hemostasis, and has good biocompatibility, controllable degradation, reduced inflammatory response, and high safety. The porous structure of the chitosan hemostatic material prepared by this invention is beneficial for tissue repair, does not adhere to other tissues, promotes healing, and has promising application prospects.

This invention provides a wound healing dressing for postoperative care of tumor patients and its preparation method, belonging to the field of postoperative dressing technology. The dressing comprises boric acid-grafted GelMA, caffeoyl tartaric acid-grafted CSMA, aldehyde-modified diallyl tartaramide, sodium alginate, catechins, ferric chloride, and calcium chloride. Its preparation process utilizes dynamic imine bonds, UV-induced covalent cross-linking, ionic cross-linking, and metal coordination to construct a multi-layered cross-linked interpenetrating network structure. The resulting dressing possesses both high strength and good toughness, allowing it to closely adhere to irregular wound surfaces. The rapid initial release of catechins provides immediate antioxidant and hemostatic effects, while catechols are continuously and slowly released under the influence of the microenvironment. Simultaneously, cationic chitosan, catechins, and iron ions synergistically provide antibacterial effects, and calcium alginate promotes coagulation, while GelMA promotes cell adhesion and proliferation, comprehensively promoting wound healing, reducing the risk of infection, and making it suitable for the care of complex wounds after tumor surgery.

The application discloses a preparation method of a composite hydrogel dressing, and is characterized by comprising the following step A1. raw material preparation: 20-40 parts of Astragalus membranaceus, 10-20 parts of Atractylodes macrocephala, 10-20 parts of Angelica sinensis, 5-15 parts of Carthamus tinctorius, 3-10 parts of dragon's blood, and 5-15 parts of Bai Zhi. The prepared composite hydrogel dressing has the characteristics of softness and hydrophilicity, can be closely attached to a wound surface of various shapes, and can well cover a flat wound surface or an irregular wound surface, so that a moist healing environment is provided for the wound surface. The moist environment is favorable for the proliferation and migration of wound cells, promotes wound healing, and can also reduce pain during dressing change. The dried hydrogel can form a porous sponge structure, the structure has strong water absorption, can quickly absorb exudates of the wound surface, keeps the wound surface dry, prevents infection caused by accumulation of the exudates, and is convenient for management of the exudates.

This invention provides a partially detachable orthopedic splint, belonging to the field of medical device technology. It includes a positioning and adjustment structure, and splint fixing structures located at both ends of the positioning and adjustment structure. Auxiliary positioning structures are provided on both sides of the splint fixing structure. By using the splint fixing structure in conjunction with the auxiliary positioning structures, during dressing changes, rotating the telescopic ring causes the two splints to move away from each other through the adjustment frame and support arm. This exposes the wound surface at the splint-covered area of ​​the fracture. Simultaneously, as the two adjustment frames move continuously, the two longitudinal sleeves move closer together, causing the positioning ring frames on both sides to move closer together, fixing the upper and lower sides of the limb fracture site. This ensures that while the wound surface is being cleaned and dressing changed, the ends of the fractured limb still have fixing structures supporting the original fixation position, greatly reducing the problem of secondary bone damage during debridement.

The application provides a VSD suction pipeline, which comprises a suction disc, a first pipeline and a second pipeline. The middle part of the suction disc is formed into a cavity which is upwardly convex. The first pipeline is communicated with the suction disc and is used for being connected to a negative pressure source. The second pipeline is communicated with the suction disc and is used for being connected to a flushing device to flush a wound surface. The VSD suction pipeline further comprises a third pipeline. The first end of the third pipeline is connected to the suction disc and the third pipeline is communicated with the suction disc. The second end of the third pipeline is connected with a pressure measuring gauge head which is used for measuring the negative pressure value in the cavity of the suction disc. The VSD suction pipeline directly measures the negative pressure value at the cavity of the suction disc by the pressure measuring gauge head, so that the medical staff can directly master the negative pressure condition of the wound surface in the suction disc.

The application discloses a kind of for cancerous ulcer wound surface closed negative pressure drainage deodorization device and its use method, it is related to medical instrument application technical field, including: wound surface fitting module, it includes by the fitting layer made of medical high polymer film, the inside surface central region of fitting layer is equipped with for covering the low-pressure distribution area of wound surface, low-pressure distribution area is equipped with micro drainage channel in, the center of micro drainage channel is communicated with drainage tube, the surface of micro drainage channel is covered with anti-adhesion layer, the inside surface edge area of fitting layer is equipped with for with the skin sealingly fitted of wound surface medical adhesive layer;1、The present application integrates multilayer filter element at the top of the liquid storage bag, and the double treatment of physical adsorption and chemical neutralization is carried out before the escape of foul gas, the activated carbon adsorbs organic foul gas in a broad spectrum, and the iron / zinc compound specifically neutralizes hydrogen sulfide and other acidic gases, completely eliminates odor from the source, solves the social and psychological distress of patients caused by foul odor, and maintains the dignity of patients.

The application provides a kind of promoting healing muscle ointment and its preparation method, the ointment is composed of PLGA slow-release microspheres encapsulating active ingredients, sodium alginate freeze-dried microspheres encapsulating EGF, ointment base and excipients, active ingredients include various raw materials such as Coptis extract, dragon's blood extract, etc., and the excipients are azone, vitamin E and polysorbate 80.The preparation method includes raw material pretreatment, preparation of two kinds of microspheres, base melting, mixed emulsification and post-processing, wherein the EGF freeze-dried microspheres are prepared by microfluidic encapsulation technology, and emulsification is carried out by microfluidic pulse homogenizer.The application realizes the multiple effects of antibacterial and anti-inflammatory, removing corruption and promoting healing, and repairing wound surface through the synergistic effect of components, can effectively protect the stability of active ingredients, prolong the efficacy, and the process is scientific and controllable.The ointment can be used for preparing drugs for promoting the healing of difficult-to-heal wounds with chronic inflammation, solving the problems of poor targeting and low healing efficiency of existing drugs, and has important clinical value and application prospect.

The application discloses a post-cesarean section anti-slipping wound compression hemostasis device and belongs to the technical field of medical devices. The device comprises an elastic band, a third air bag installed on the inner side of the elastic band, and a compression mechanism located on the outer wall of the elastic band and used for expanding the third air bag to stop bleeding of a patient's wound. The compression mechanism comprises an auxiliary component arranged on the outer wall of the elastic band. The third air bag is flexibly connected to the surface of the wound and has no sharp edges or hard points, so that friction and tearing of the sutured wound and damaged skin can be avoided, the integrity of the wound surface is protected, skin ulcer and nerve damage (such as the "local pressure sores" risk of a traditional hemostasis band) caused by excessively high local pressure can be avoided, the third air bag can be inflated to be attached to the curved surface of the human body, the problem of poor attachment and pressure dead angle caused by rigid compression is solved, and the recovery effect of the incision of the patient after the cesarean section is improved.

This application provides a self-generating nano-silver PVDF composite fiber, comprising polyvinylidene fluoride (PVDF) and nano-silver, which are combined via electrospinning. By introducing AgNPs into the piezoelectric material PVDF and fabricating it into micro-electric nanofibers using electrospinning, this fiber possesses both the long-lasting, broad-spectrum antibacterial properties of nano-silver and the ability to continuously generate microcurrents on the wound surface. It does not rely on external devices such as fixed power supplies and electrode pads required for commonly used clinical electrical stimulation, making it highly significant and effective in reducing post-burn / traumatic infection, promoting wound healing, and ensuring patient safety and timely recovery. This solves the problem of poor stability and environmental limitations of PVDF nanocomposite membranes, which negatively impact wound healing. This application also provides a method for preparing the self-generating nano-silver PVDF composite fiber and its application in preparing dressings for treating burns and wounds.

The application discloses a kind of biological membrane dressings and its application in the treatment of multiple types of injuries, the dressing with egg white, fibrinolysin, soybean small molecule peptide as main film-forming matrix, can be selectively added to one or more active ingredients of Chinese herbal medicine, such as radix cirsii japonici, bletilla striata, portulaca oleracea, radix pteroxygoni, sophora flavescens, panax notoginseng, menthol powder, according to different wound types, can be made into ready-to-use gel or freeze-dried powder.The biological membrane dressing provided by the application can quickly form a dense protective film on the wound surface, physically seal the wound, effectively prevent fluid loss and bacterial infection, so as to skip the shock period and inflammation period.The dressing has the effects of rapid analgesia, detumescence, scabbing and promoting healing, and can significantly inhibit scar formation, and is suitable for the treatment of burns and scalds, surgical incisions, abrasions, chronic ulcers, diabetic foot, urticaria, herpes zoster, frostbite, penetrating wounds, lacerations, sprains, strains, contusions, arthritis, bone repair, animal bites, fungal infections and skin inflammation and the treatment of various injuries.

The application discloses a negative pressure drainage dressing with controllable shrinkage direction, which comprises a dressing body for covering a wound surface, a sealing film arranged on the top of the dressing body and used for fixing the dressing body at the wound surface and forming a sealed environment, a negative pressure device arranged in the dressing body and used for generating negative pressure to discharge exudate, an adjusting mechanism arranged in the middle of the dressing body, and a plurality of control lines arranged in the dressing body, one end of each control line being fixed to the edge of the dressing body and the other end being connected to the adjusting mechanism, and the adjusting mechanism driving the dressing body to uniformly shrink to the center by gathering the corresponding control lines. The negative pressure drainage dressing has the advantages of simple structure, convenient operation and controllable directional tension.