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45 results about "Extravasation" patented technology

Extravasation is the leakage of a fluid out of its container. In the case of inflammation, it refers to the movement of white blood cells from the capillaries to the tissues surrounding them (leukocyte extravasation), also known as diapedesis. In the case of malignant cancer metastasis it refers to cancer cells exiting the capillaries and entering organs. It is frequently used in medical contexts, either referring to urine, or to blood.

Image-enhanced peripheral vein puncture blood vessel pressure monitoring system based on multi-modal fusion

The invention discloses a peripheral vein puncture blood vessel pressure monitoring system for image enhancement examination based on multi-modal fusion, and relates to the technical field of medical image assistion.The peripheral vein puncture blood vessel pressure monitoring system comprises the steps that image data, sensor data and personalized data of a patient are collected; generating an image feature vector, a sensor feature vector and a personalized feature vector based on the preprocessed multi-modal data, carrying out feature interaction on a multi-modal feature line, carrying out representation fusion by combining Transform with contrast learning, and generating a fusion representation vector; the maximum tolerance pressure, the extravasation risk level and the recommended injection flow rate range of the target puncture point under the current injection flow rate are predicted and evaluated in the blood vessel pressure resistance prediction model, injection suggestions and injection alarms of the target puncture point are generated, and injection parameters are automatically adjusted. According to the method, the personalized safety pressure threshold values of patients with different blood vessel conditions are accurately evaluated, and the safety and accuracy of peripheral vein puncture are remarkably improved.
Owner:SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV

Percutaneous kidney lithotripsy surgery endoscope and use method thereof

The invention discloses a percutaneous kidney lithotripsy surgery endoscope and a using method thereof. The percutaneous kidney lithotripsy surgery endoscope comprises an electronic endoscope, an endoscope sheath assembly, a guide wire and a puncture needle. The electronic endoscope and the puncture needle are both internally provided with instrument channels allowing the guide wire to penetrate through, and the electronic endoscope is provided with a two-way valve assembly matched with the guide wire to achieve two-way sealing. The two-way valve assembly comprises a two-way valve plate, the two sides of the two-way valve plate are locally sunken towards the middle to form an upper pressing face and a lower pressing face, and a sealing gap for a guide wire to penetrate through is formed between the two pressing faces. Reliable two-way sealing of the whole penetrating, staying and operating process of the guide wire is achieved, leakage of expanded cavity liquid and entering of external air can be effectively prevented, the working pressure in the kidney is stably maintained, the clear operation view is guaranteed, complications such as postoperative infection and perirenal liquid exosmosis are reduced, smooth operation of the guide wire is not hindered, the operation safety and controllability are improved, and the operation efficiency is improved. The structure is reasonable and practicability is high.
Owner:HANGZHOU HAWK OPTICAL ELECTRONICS INSTR CO LTD

A kind of high-pressure syringe device of anti-seepage and explosion-proof automatic pressure control

The application discloses an anti-seepage and anti-explosion automatic control pressure high-pressure injector device and belongs to the field of image contrast diagnosis and treatment equipment. The device comprises a driving pushing unit and an injection cylinder. A hose is connected to the discharge end of the injection cylinder through a joint. A first pressure sensor, a second pressure sensor and a buffer are sequentially installed on the hose. The first pressure sensor is close to the discharge end of the injection cylinder. The buffer is arranged downstream of the second pressure sensor. A movable block in the buffer can divide a liquid channel of the connected hose and a volume-adjustable exchange chamber. The driving pushing unit is transmissionally connected to an injection plug in the injection cylinder and is electrically connected to a control box receiving signals of the two sensors. The application can compare and distinguish two types of faults, i.e. blockage and overload in the cylinder and blockage of the distal pipeline, by means of the double sensors, so that the control system can be stopped in advance for protection, the defects of lagging and poor fault tolerance of single pressure detection and identification can be made up, medical risks such as extravasation of contrast medium, pipeline burst and blood vessel injury can be reduced, the injection pressure is stable and controllable, and medical staff need not to be on duty for a long time.
Owner:中国人民解放军总医院第八医学中心

Intravenous monitoring system

A venous monitoring system is disclosed that can include a fluid passageway formed in a housing to receive and direct fluid through the housing, a sensor coupled to the fluid passageway to detect data of the fluid in the fluid passageway, a communication unit to communicate data sensed by the sensor, and a power source, wherein the system of the present disclosure can be used for venous monitoring when coupled to a catheter or an intravenous set, or can include a catheter needle extending from the housing, and wherein the system of the present disclosure can detect characteristics such as placement of a catheter, fluid passageway occlusion or patency, and catheter extravasation or infiltration.
Owner:CAREFUSION 303 INC

Hemostasis fixing device for blood sampling

The invention discloses a hemostasis fixing device for blood sampling, and belongs to the technical field of medical instruments, the hemostasis fixing device comprises a fixing assembly which comprises a connecting belt and a fixing belt movably connected with the connecting belt; the hemostasis component is arranged between the connecting band and the fixing band; comprising a shell arranged between the connecting band and the fixing band, a power piece penetrating through the top of the shell and movably connected with the top of the shell, an adjusting piece arranged in the shell and fixedly connected with the end of the power piece, a positioning piece arranged in the shell and arranged in the middle of the adjusting piece in a sleeving mode, and a pressing pad arranged at the end of the adjusting piece. The hemostasis device has the advantages that by arranging the fixing assembly, the hemostasis assembly can be fixed to the wound of a patient, the hemostasis assembly plays a role in pressing and hemostasis on the blood collection wound, the wound can be evenly pressed, the problem that pressure is not uniform when traditional manual pressing hemostasis is conducted is solved, and local skin extravasation or subcutaneous hematoma is effectively reduced.
Owner:NANJING DRUM TOWER HOSPITAL

System and methods for measuring patient-specific extravasation dosimetry

A system and method for determining accumulated radiation dose is presented. In some embodiments, the system and method include use of one or more RADFETs to measure and accumulated radiation dose over a desired period of time from an area of interest in a patient. In some embodiments, the one or more RADFETs may be arranged on a test strip, and electrical circuitry provided to selectively couple certain terminals of the RADFETS together to facilitate improved measurement of accumulated dose. A reader may also be utilized wherein the reader may receive a test strip, decouple the electrical connections between select terminals, inject a current into the RADFET and / or measure a voltage from the RADFET corresponding to an accumulated radiation dose.
Owner:LUCERNO DYNAMICS LLC

An outpatient infusion exosmosis risk early warning method and system

This application relates to a method and system for early warning of extravasation risk in outpatient infusions. The method includes: extracting corresponding visual frames, physiological signal data points, and medical event records from real-time acquired visual frame sequences, physiological signal sequences, and medical event streams; extracting and integrating features from these data to construct spatiotemporal sample units; inputting these spatiotemporal sample units into a gated spatiotemporal joint encoder to generate potential risk states characterizing the comprehensive risk status at the current moment; adding these potential risk states to a risk potential state sequence maintained for the patient to obtain an updated risk potential state sequence; performing risk analysis based on the updated risk potential state sequence to generate an evidence chain; and performing decision mapping based on the evidence chain to generate a decision report. This method, through multimodal spatiotemporal data fusion and a gated dynamic coding mechanism, achieves real-time and accurate perception and dynamic evolution modeling of extravasation risk, improving the intelligence level of outpatient infusion safety monitoring and the timeliness of risk intervention.
Owner:THE 958TH ARMY HOSPITAL OF THE CHINESE PEOPLES LIBERATION ARMY

A postoperative biliary fistula risk prediction system for hepatobiliary surgery patients

This invention discloses a postoperative bile fistula risk prediction system for hepatobiliary surgery patients, belonging to the field of bile fistula risk data processing technology. The system includes an evidence-driven variable acquisition module, a standardization judgment module, a time-series feature generation module, a feature screening module, and a dynamic prediction module. It performs time-series reconstruction and evolutionary feature extraction for dynamic monitoring indicators of postoperative bile extravasation. Through a structural-biochemical consistency constraint screening method, it fuses and filters features of structural risk channels, biochemical risk channels, and time-series evolution channels. Based on core predictive feature data, it constructs a bile fistula risk prediction model and dynamically predicts the probability of bile fistula occurrence at different postoperative time points through a time-series rolling update mechanism, outputting risk levels and early warning results. This invention enables early identification, dynamic assessment, and individualized intervention support for bile fistula risk, improving the accuracy of prediction results and its clinical application value.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

Multi-parameter integrated intravenous infusion extravasation early warning method and device

The invention relates to a multi-parameter integrated intravenous infusion extravasation early warning method and device. The method comprises the steps that firstly, a physiological parameter set of a patient is collected through medical equipment, and a structured feature data set is constructed through standardization processing; secondly, dynamic modeling is conducted on the feature data set through a deep learning time sequence model, and a self-adaptive datum line and a potential exosmosis risk sequence are generated; and then, carrying out signal processing on the risk sequence, extracting multi-device associated characteristics, calculating a collaborative risk coefficient, and iteratively updating the adaptive reference line to obtain a risk judgment result. And finally, determining a final extravasation risk value according to a judgment result, comparing the final extravasation risk value with a historical threshold value, and then triggering a dynamic early warning signal of a corresponding level. By means of the method, exosmosis risks can be accurately evaluated, the problem that the adaptability of fixed threshold monitoring is insufficient is effectively solved, an automatic and intelligent solution is provided for clinical infusion exosmosis prevention, the nursing burden is reduced, and the safety of a patient is improved.
Owner:LANZHOU UNIV SECOND HOSPITAL

Liquid medicine filter with anti-external leakage structure

ActiveCN224292952USemi-permeable membranesExtravasationMechanical engineering
The utility model discloses a liquid medicine filter with prevent extravasation structure, and the upper cover includes the cover body, the top surface middle part of cover body is fixedly connected with the extension piece, and extension piece sets up four in all, each extension piece all equidistance arrangement around the central axis of cover body, and each extension piece is fixedly connected with a plurality of clamping teeth on the side upper end of cover body middle part, each clamping tooth all equidistance arrangement along the length direction of extension piece, and the lower extrusion ring is still fixedly connected on the upper end of one side of extension piece away from clamping tooth, and the outer diameter of lower extrusion ring gradually increases from top to bottom, and each extension piece and clamping tooth are integrally formed, and install the upper connector on the top of upper cover, thereby convenient connection to the inside of external connecting pipeline, and the outer wall of upper connector is fixed with the anti -pull ring, and the contact area of joint and pipeline is increased, and the axial anti -pulling force is improved, and the outer side of anti -pull ring is fixed with the sealing ring made of flexible material, and then the connecting gap is reduced, and the friction between upper connector and external pipeline is also increased, and further prevent breaking away.
Owner:XI AN FENG HUA YAO YE YOU XIAN GONG SI

Dynamically generating a treatment path for extravasation or infiltration

A treatment path for extravasation or infiltration can be dynamically generated. A system can be configured to allow a clinician to select a drug that was being administered to a patient when a suspected infiltration or extravasation occurred. When the clinician selects a drug, the system can be configured to present various values for each of multiple characteristics applicable to infiltration and extravasation where sets of these values are grouped to define various grades for the infiltration or extravasation. Accordingly, the clinician can select a grade that is associated with a set of values that best represent the characteristics the patient is exhibiting. Based on the selected drug and grade, the system can dynamically generate a treatment path and present the treatment path to the clinician for immediate action. In this way, the infiltration or extravasation can be accurately and immediately treated to thereby minimize harm to the patient.
Owner:IV LEAKS LLC

Intelligent early warning type nursing fixing device for preventing extravasation during venous transfusion of critical patient

The invention provides an intelligent early-warning type nursing fixing device for preventing extravasation during venous transfusion of a critical patient, and relates to the technical field of medical nursing equipment, the intelligent early-warning type nursing fixing device comprises a flexible outer shell, an early-warning assembly for warning leakage of venous transfusion is mounted at the outer end of the flexible outer shell, and clamping grooves are formed in the front side and the rear side of the early-warning assembly; a limiting assembly is installed in a clamping groove of the early warning assembly, a groove is formed in the outer surface of the early warning assembly, a positioning assembly is arranged in the groove of the early warning assembly, the lower surface of the positioning assembly abuts against the upper surface of the limiting assembly, the flexible outer shell is attached to the outer side of the infusion position of a patient, and the device is fixed to the limb of the patient through the early warning assembly. The limiting assembly further strengthens the fitting degree of the device and the limbs, the positioning assembly locks the installation state of the limiting assembly, the device can meet the nursing requirements that the limbs of the critical patient are limited in movement and long-term infusion is needed, and therefore the nursing safety, the fixing reliability and the intelligent early warning performance of the device are improved.
Owner:HAINAN PROVINCIAL PEOPLES HOSPITAL

An early determination method of infusion extravasation and related equipment

The application discloses a kind of early determination methods and related equipment of infusion extravasation, the method constructs local space temperature gradient distribution around infusion puncture point, and establishes the space temperature distribution model that can update with time with puncture point as center, time series analysis is carried out to the space temperature distribution model in preset time window, and characteristic parameters such as temperature gradient change quantity and abnormal temperature region space diffusion rate are extracted.By comparing the characteristic parameters with preset determination threshold, and combining duration condition, early risk state of infusion extravasation is determined and early warning signal is output.The application realizes early, continuous and objective identification of infusion extravasation risk by jointly analyzing the space distribution characteristics and time evolution law of skin temperature, does not depend on patient complaint or artificial patrol, and can effectively reduce false alarm rate.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH

A traditional Chinese medicine composition for improving hand-foot-mouth disease

PendingCN122229968AAntiviralsPlant ingredientsEnterovirusMedicinal herbs
This invention discloses a traditional Chinese medicine composition for assisting in the improvement of hand-foot-mouth disease in infants and young children, belonging to the field of traditional Chinese medicine technology. The composition consists of eight medicinal herbs: lotus leaf, coix seed, angelica dahurica, kudzu root, platycodon root, agastache rugosa, cimicifuga rhizome, and dandelion, with a defined optimal medicinal ratio. Based on the seasonal differences in the pathogenesis of hand-foot-mouth disease, this invention targets the core pathologies of winter (cold congestion of microvessels, water and sodium retention, and internal heat generation) and spring and summer (hypothalamic sympathetic activation, increased heart rate, and visceral heat overload). It also addresses the technical deficiencies of clinical Western medicine, cold-natured traditional Chinese medicine, calamine lotion, and diuretics, such as vasoconstriction, kidney damage, central nervous system disorders, increased skin exudation, and rebound water retention. This invention employs a combination of warming and cooling herbs, regulating the ascending and descending functions, and promoting diuresis and protecting the body's vital energy. The synergistic effects of these herbs can dilate spasmodic microvessels, improve renal perfusion, stabilize abnormal heart rates, stabilize the hypothalamic center, and assist in antagonizing enteroviruses. By targeting and reducing abnormal permeability of skin capillaries with Angelica dahurica and Platycodon grandiflorus, it reduces blood extravasation and inhibits the formation and exudation of herpes from the root cause. This invention has mild medicinal properties, is suitable for all seasons, and has high safety. It can effectively improve symptoms of hand-foot-mouth disease such as fever, herpes, irritability, and cold extremities, reduce the risk of severe illness, antagonize the toxic side effects of commonly used clinical drugs, and is suitable for the delicate constitution of infants and young children, possessing good prospects for clinical application and promotion.
Owner:YINGXUAN TRADITIONAL CHINESE MEDICINE TECHNOLOGY (HENGZHOU) CO LTD

Extravasation detection device, extravasation detection system, and program

Provided are an extravasation detection device, extravasation detection system, and program, which are capable of more easily detecting extravasation even when detection in a peripheral blood vessel is difficult. An extravasation detection device 1 acquires, from a blood flow measurement device 4, a measurement value related to a blood flow state in the heart H of a patient P with an indwelling needle inserted at a predetermined site 7 of the body before and after administration of an infusion solution trough the indwelling needle, determines whether or not the infusion solution is correctly administered on the basis of the acquired measurement value, and outputs a determination result.
Owner:KOJIMA TAIKI +1

Improved infusion apparatus for monitoring venous exosmosis

The invention relates to the technical field of medical equipment, and discloses an improved infusion apparatus for monitoring venous exosmosis, comprising: a Murphy's dropper made of an elastic material, the Murphy's dropper having a cavity for forming liquid drops; a first electrode and a spiral flow guide rib are arranged in the cavity of the Murphy dropper; the first electrode is used for monitoring dripping of liquid drops, and the first electrode is fixed in an interference fit mode through a mounting hole in the center of the spiral flow guide rib; moreover, the host is configured to ignore a signal as invalid data when identifying that the change rate of the liquid dropping interval exceeds 10 times of a normal threshold value and the duration time is less than 2 seconds. By integrally forming the elastic cleaning scraper on the inner wall of the Murphy's dropper, an electrode cleaning mechanism which is extremely simple, reliable and low in cost is provided, and medical staff can effectively and physically scrape and clean an electrode as required and timely remove liquid medicine residues attached to the surface of the electrode only through simple dropper pressing action.
Owner:自贡市第一人民医院

Anti-exosmosis ascites collection device

The utility model is suitable for the technical field of medical equipment, and provides an anti-exosmosis ascites collecting device. Comprising a chassis, an ostomy bag, a drainage tube and a drainage bag, the chassis comprises an outer ring, an inner ring arranged in the middle of the outer ring and a plurality of threaded caps, a through hole is formed in the inner ring, a threaded boss is further arranged in the middle of the inner ring, mounting through holes are formed in the middles of the threaded caps, and the diameters of the mounting through holes of the threaded caps are unequal; the thread cap is used for being installed on the thread boss. The ostomy bag is arranged on the base plate, the ostomy bag is of an annular structure, the outer edge of the ostomy bag is installed on the outer ring, and the inner side of the ostomy bag is installed on the inner ring; the ostomy bag is communicated with the drainage bag through the flow guide tube, the drainage tube penetrates through the through hole in the inner ring and the installation through hole of the threaded cap, and one end of the drainage tube is communicated with the drainage bag through the drainage extension tube.
Owner:ZHONGSHAN HOSPITAL AFFILIATED TO FUDAN UNIV XIAMEN HOSPITAL

Intelligent infusion management method, system and application

The invention belongs to the technical field of infusion management, and provides an intelligent infusion management method and system and application, and the method comprises the steps: obtaining static feature data and chemotherapy treatment data of a patient; obtaining time sequence monitoring data of the puncture area, and performing preprocessing and feature extraction on the time sequence monitoring data to obtain a dynamic feature vector; inputting the static characteristic data and the chemotherapy treatment data into a first machine learning model for processing, and outputting a baseline risk probability; inputting the dynamic feature vector into a second machine learning model for processing and outputting a real-time abnormal probability; fusing the baseline risk probability and the real-time abnormal probability to obtain a comprehensive risk score; dynamically adjusting an early warning threshold based on the baseline risk probability; when the comprehensive risk score exceeds the adjusted early warning threshold value, generating and pushing an early warning signal; and optimizing and updating the first machine learning model and the second machine learning model based on the early warning signal and the corresponding clinical verification result. The chemotherapeutic drug extravasation early warning system can realize early and accurate early warning of chemotherapeutic drug extravasation.
Owner:JILIN UNIV FIRST HOSPITAL

Extravascular leakage detection device, extravascular leakage detection system, and program

This invention provides an extravasation detection device, an extravasation detection system, and a program that enable easier detection of extravasation, even in cases where detection in peripheral blood vessels is difficult. [Solution] The extravasation detection device 1 includes: a first measurement value acquisition unit 11 that acquires a first measurement value related to the blood flow state during the administration of intravenous fluid from the indwelling needle 5 at a first measurement position B1 in the blood vessel L near the insertion position A1 where the indwelling needle 5 is inserted into the blood vessel L of patient P; a second measurement value acquisition unit 12 that acquires a second measurement value related to the blood flow state before and after the administration of intravenous fluid from the indwelling needle 5 at a second measurement position B2 corresponding to the first measurement position B1; a determination unit 14 that determines whether or not intravenous fluid administration is being performed normally by comparing the first measurement value acquired by the first measurement value acquisition unit 11 and the second measurement value acquired by the second measurement value acquisition unit 12; and a determination result output unit 15 that outputs the determination result from the determination unit 14.
Owner:JMS CO LTD

Chemotherapy outpatient anti-extravasation chemotherapy dosing device

The present application relates to the technical field of medical devices, in particular to a chemotherapy outpatient anti-extravasation chemotherapy dosing device, comprising a transfusion tube, a hydraulic collection assembly is arranged on the transfusion tube, a drip speed collection assembly is arranged outside the drip tube, the hydraulic collection assembly is signal connected with a controller, the controller is electrically connected with a strain collection assembly, whether the current transfusion process is abnormal is comprehensively judged through the hydraulic change information of the drug solution delivery and the drip speed change information in the drip tube, and whether there is drug solution extravasation is judged in combination with the tension change of the patient's puncture point; a valve assembly is arranged on the transfusion tube, and a drug solution recovery assembly is further arranged below the valve assembly, when drug solution extravasation occurs in the patient's transfusion process, the valve assembly is driven to block the drug solution delivery, and the drug solution recovery assembly recovers the residual drug solution in the transfusion tube. The present application integrates hydraulic, drip speed and skin tension multi-dimensional data monitoring, when chemotherapy drug delivery extravasation is detected, the drug solution delivery is blocked, and the residual drug solution is cleaned and recovered, so that the defect of continuous drug delivery after existing drug delivery extravasation is solved.
Owner:PEOPLES HOSPITAL PEKING UNIV

Extravascular leakage detection device, extravascular leakage detection system, and program

This invention provides an extravasation detection device, an extravasation detection system, and a program that enable easier detection of extravasation, even in cases where detection in peripheral blood vessels is difficult. [Solution] The extravasation detection device 1 acquires measurements from the blood flow measuring device 4 regarding the blood flow state in the heart H of patient P, in which an indwelling needle has been inserted at a predetermined site 7 in the body, before and after the administration of intravenous fluid from the indwelling needle. Based on the acquired measurements, it determines whether or not the intravenous fluid administration is being performed normally and outputs the determination result.
Owner:小嶋 大樹 +1

Anti-exosmosis chemotherapy dosing device for medical oncology

PendingCN121846503APrecisely adjust on-offAccurately adjust flow volumeMedical devicesIV ChemotherapyTumor chemotherapy
The invention discloses an anti-exosmosis chemotherapy dosing device for medical oncology, which belongs to the technical field of tumor chemotherapy and comprises a moving rod, a support rod is fixedly mounted at the top end of the moving rod, a dosing bottle is arranged on one side of the support rod, and an infusion mechanism forming a gas-liquid pressure self-balancing system is arranged at the bottom end of the dosing bottle. The infusion mechanism comprises an injection head inserted into a bottle opening of the medicine feeding bottle, a first connecting block is arranged on the injection head, and an infusion tube is installed at the free end of the injection head in a communicating mode. Meanwhile, redundant liquid can be rapidly shunted and reflowed through the backflow pipe, the backflow pressure peak value can be effectively absorbed through a buffering bag supported by a honeycomb support in the flow slowing cavity, vortex can be avoided through a built-in flow guiding component and a flexible silica gel miniature flow limiting valve, and the problem of damage caused by too high pipeline pressure is solved to the maximum extent.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

An enterostomy device for use after complex enteroclysis

ActiveCN224505706UBowel adhesionPharmacy medicine
The utility model discloses a kind of enterostomy devices applied to complex postoperative enteric adhesion, comprising: double-layer catheter fixing assembly and stoma bag;Double-layer catheter fixing assembly is cooperated through base, main cavity pipeline and metal fixing sheet, and catheter is stably fixed, and it is prevented from slipping displacement;Main cavity pipeline three-layer structure, outer spiral layer toughening pressure resistance, middle layer air bag layer self-adapting inflation and deflation, inner hydrophobic layer smooth diversion, auxiliary cavity pipeline check valve design, it is convenient to postoperative cleaning and drug delivery, stoma bag adopts waterproof, water absorption, antibacterial three-layer structure, prevent leakage infection, capacity monitoring sensor real-time monitoring, bluetooth reminds replacement, transparent observation window is convenient for observing excrement;The utility model effectively solves the problem that catheter is not fixed in prior art, cannot be negative pressure drainage, excretion extravasation nursing is complicated, improves the comfort of patient and the convenience and safety of nursing.
Owner:CHINESE PEOPLES ARMED POLICE FORCE SHANGHAI GENERAL HOSPITAL

Micro-fluidic chip for simulating tumor metastasis cascade process and preparation method of micro-fluidic chip

The invention belongs to the field of biomedical engineering, and relates to a microfluidic chip for simulating a tumor metastasis cascade process, which sequentially comprises a substrate (1), a middle-layer porous film (2) and a cover plate (3) from bottom to top, a U-shaped channel (4) is formed in one surface, close to the middle-layer porous film (2), of the substrate (1); a left side channel (5) and a right side channel (6) are formed in one surface, adjacent to the middle-layer porous film (2), of the cover plate (3); the substrate (1), the middle-layer porous film (2) and the cover plate (3) are tightly bonded, the left side channel (5) is overlapped with a left side channel of the U-shaped channel (4), and the right side channel (6) is overlapped with a right side channel of the U-shaped channel (4). The micro-fluidic chip disclosed by the invention can be used for simulating a tumor primary focus and a metastasis microenvironment, and simulating a whole tumor metastasis cascade process including a plurality of stages of tumor cell infiltration, circulation, extravasation and colonization in vitro.
Owner:HENAN ACADEMY OF SCIENCES ORGANOID CHIP & DRUG TRANSLATION RESEARCH INSTITUTE

Methods and apparatus for monitoring intravenous catheter infiltration

PendingUS20250375572A1Medical devicesFlow monitorsTissue edemaVein
Embodiments are directed to an automated system that provides statistical confirmation of the non-infiltrated state of a functioning PIV and a clear signal associated with an infiltrated PIV identifying conditions associated with infiltration / extravasation before rather than after the onset of a noxious event such as tissue edema or damage.
Owner:BOARD OF RGT THE UNIV OF TEXAS SYST

Sensing catheter

The present disclosure relates to sensing catheters. A catheter system can include a catheter lumen, a first electrode and a second electrode, and a sensor in communication with the first electrode and the second electrode. The sensor can be configured to detect at least one of: an extravasation of a bolus of blood within a blood vessel and a drug from the blood vessel into soft tissue near the blood vessel. Other catheter systems can include a catheter lumen and a sensing chip coupled to the catheter lumen. The sensing chip can be configured to detect at least one of: an extravasation of a bolus of blood within a blood vessel and a drug from the blood vessel into soft tissue near the blood vessel.
Owner:BECTON DICKINSON & CO

Methods and apparatus for monitoring intravenous catheter infiltration

Embodiments are directed to an automated system that provides statistical confirmation of the non-infiltrated state of a functioning PIV and a clear signal associated with an infiltrated PIV identifying conditions associated with infiltration / extravasation before rather than after the onset of a noxious event such as tissue edema or damage.
Owner:BOARD OF RGT THE UNIV OF TEXAS SYST

Anti-exosmosis chemotherapy dosing device for medical oncology

The invention relates to an anti-exosmosis chemotherapy dosing device for medical oncology, and belongs to the field of medical instruments. Comprising a frame body and a medicine bottle, a base and two mounting boxes are arranged below the medicine bottle, the two mounting boxes are both slidably connected with the base, an annular frame is arranged above the base, and a fixing plate is fixedly connected between the annular frame and the base; and a positioning mechanism is arranged on the annular frame. By arranging the drug delivery mechanism, uniform and stable delivery of chemotherapy liquid medicine can be achieved, a driving shaft rotates to drive a first movable block on the inner wall of a movable ring to move in a guide groove, the first movable block can drive the movable ring to slowly move in the axial direction of the driving shaft under the action of a spiral groove, and meanwhile a first spring is compressed; and when the first movable block enters the strip-shaped groove from the spiral groove, the movable ring rapidly resets under the action of the elastic restoring force of the first spring, and the circulation is carried out, so that the movable ring generates axial reciprocating motion, and slow advancing and rapid retreating of the extrusion wheel are realized.
Owner:WUXI NO 2 PEOPLES HOSPITAL