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49 results about "Postoperative infection" patented technology

Post-plastic-surgery infection early warning method and system based on multi-modal data fusion

The embodiment of the invention provides a multi-modal data fused postoperative plastic surgery infection early warning method and system. The method comprises the following steps: firstly, performing quality evaluation and restoration on postoperative wound images, clinical texts, wearable vital signs and baseline features; performing double-flow coding and priori segmentation on the repaired image to obtain a coarse mask; constructing a super-pixel graph, obtaining a topological consistent fine mask through a graph neural network, and quantifying the erythema / exudation area; the text and the vital signs are coded respectively and then fused with the image features and the masks through cross-attention and self-attention, and a fusion implicit vector and uncertainty are obtained through quality weight gating; an individualized dynamic threshold value is constructed by combining baseline risk, logarithmic probability calibration and a sliding window trend, a confidence band is output by using conformal prediction, and early reliable infection early warning is realized.
Owner:PLASTIC SURGERY HOSPITAL CHINESE ACADEMY OF MEDICAL SCIENCES

Postoperative infection monitoring and early warning method and system

The invention discloses a postoperative infection monitoring and early warning method and system, and relates to the technical field of clinical monitoring, and the method comprises the steps: collecting a postoperative infection multi-source alignment data set, building an individual reference model, dynamically extracting postoperative change features, building a behavioral physiological coupling model, recognizing abnormal interaction, and quantifying the infection risk. According to the method, multi-source data are fused, an individualized dynamic baseline model and a behavior-physiological coupling model are established, intelligent recognition and grading early warning of postoperative infection risks are achieved, and the method is high in practicability and easy to popularize. Model parameters are automatically corrected by utilizing a self-learning and feedback recharge mechanism, a closed-loop process of monitoring, prediction, intervention and optimization is formed, infection symptoms can be recognized in advance, manual dependence is reduced, the real-time performance and accuracy of postoperative infection prevention and control are improved, and intelligent decision support is provided for clinic.
Owner:THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIV

Composite hydrogel loaded with herba violae exosome as well as preparation method and application of composite hydrogel

The invention belongs to the technical field of biomedical materials, and discloses a viola philippica exosome-loaded composite hydrogel as well as a preparation method and application thereof, the composite hydrogel is prepared by mixing methacrylated polylysine (PLMA), oxidized dextran (ODex), viola philippica exosome (V-E), a photoinitiator and a physiologically compatible solvent and performing illumination crosslinking; the preparation method comprises the following steps: respectively preparing PLMA and ODex solutions, extracting and purifying V-E, adding a photo-crosslinking agent (LAP), mixing the components to obtain a precursor liquid, and carrying out in-situ curing molding through ultraviolet-visible light irradiation. The composite hydrogel provided by the invention solves the problems that the existing wound dressing is difficult to fit with irregular wounds, is antibacterial and easy to resist drugs, and lacks active anti-inflammatory and efficient healing promotion capabilities, and is suitable for repair treatment of infectious open wounds such as burns, trauma, diabetic foot ulcer and postoperative infected incisions.
Owner:THE FIRST AFFILIATED HOSPITAL OF GUANGDONG PHARMACEUTICAL UNIVERSITY

A post-plastic surgery infection early warning method and system based on multi-modal data fusion

The method of the embodiment of the application proposes a multi-modal data fusion postoperative infection early warning method and system. First, the postoperative wound image, clinical text, wearable vital signs and baseline features are quality evaluated and repaired. The repaired image is double-flow encoded and the coarse mask is obtained by prior segmentation. The superpixel graph is constructed and the topologically consistent fine mask is obtained by the graph neural network to quantify the erythema / effusion area. The text and vital signs are encoded and fused with the image features and the mask through cross-attention and self-attention, and the fused hidden vector and uncertainty are obtained through the quality weight gate. The individualized dynamic threshold is constructed by combining the baseline risk, the logit calibration and the sliding window trend, the shape-preserving prediction output confidence band is used to realize the early and reliable infection early warning.
Owner:PLASTIC SURGERY HOSPITAL CHINESE ACADEMY OF MEDICAL SCIENCES

A method for preparing an antibacterial biological patch for cardiac surgery and the product thereof

PendingCN122624749AGlycerolPericardium
The application discloses a preparation method of an antibacterial biological patch for cardiac surgery, and comprises the following steps: first, preparing a Fib@CMC@ABX mixed solution; second, preparing a cross-linking solution, pouring the cross-linking solution on the surface of the biological patch, and sealing and storing the cross-linking solution at 4 DEG C after cross-linking reaction; third, placing; and fourth, soaking in a glycerol solution. The antibacterial coating of the antibacterial biological patch for cardiac surgery prepared by the preparation method is not easy to fall off or crack, the antibacterial coating is firmly attached to the biological patch, the continuity of the antibacterial coating is good, the antibacterial coating has long-acting antibacterial effect, can effectively inhibit bacterial growth, and can prevent postoperative infection, and is suitable for cardiac surgery scenes such as heart repair and pericardial reconstruction.
Owner:BEIJING BALANCE MEDICAL

Antibacterial gelatin microspheres with photodynamic effect as well as preparation method and application of antibacterial gelatin microspheres

The invention discloses an antibacterial gelatin microsphere with a photodynamic effect and a preparation method and application of the antibacterial gelatin microsphere, and belongs to the technical field of biomedical materials and hemostasis. An olefinic unsaturated carboxylic acid monomer is grafted to a gelatin side chain through amidation reaction to obtain modified gelatin; the modified gelatin and a cross-linking agent free radical are subjected to a copolymerization reaction to form carboxyl functionalized gelatin microspheres, and a photosensitizer is covalently immobilized on the surfaces of the carboxyl functionalized gelatin microspheres through an esterification reaction to prepare the antibacterial gelatin microspheres with the photodynamic effect. According to the antibacterial gelatin microspheres with the photodynamic effect and the preparation method and application of the antibacterial gelatin microspheres, the efficiency and stability of subsequent photosensitizer loading can be remarkably improved, the postoperative infection risk is effectively solved, and the limitation that a traditional hemostatic material only pays attention to physical plugging is broken through.
Owner:THE AFFILIATED SIR RUN RUN SHAW HOSPITAL OF SCHOOL OF MEDICINE ZHEJIANG UNIV

Postoperative chest drainage fixing device for thoracic surgery department

The utility model belongs to the technical field of medical auxiliary equipment, and particularly relates to a thoracic surgery postoperative chest drainage fixing device which comprises a shell, and the back face of the shell is connected with a surgery binding belt; the sliding grooves are formed in the side face of the shell in an annular distribution mode, clamping blocks are connected into the sliding grooves in a sliding mode, the clamping blocks are hollow, and through holes are evenly formed in the arc-shaped ends of the clamping blocks; the adjusting mechanism is arranged on the shell, and when the adjusting mechanism operates, the multiple clamping blocks are driven to be close to or away from each other; the negative pressure mechanism is connected to the clamping block; the guide rods are annularly distributed and connected to the outer surface of the shell; and the limiting mechanism is arranged at the guide rod. The drainage tube can be effectively prevented from falling off, the risk of damage to the drainage tube material is reduced, smooth discharge of gas and blood in the thoracic cavity is guaranteed, postoperative infection can be prevented, and wound healing is promoted.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Pasting film for otologic operation

ActiveCN223831190UEar treatmentSurgical drapesEar operationsThin membrane
The utility model discloses a pasting film for otology operation, which belongs to the technical field of medical consumables and comprises a film body, a liquid collecting hopper connected with the film body for forming, a connecting film, a second opening arranged on the surface of the connecting film and corresponding to the first opening, and the liquid collecting hopper is connected with the film body for forming. And a strip-shaped side opening communicated with the second opening is formed in the surface of the connecting film. The ear protection film has the beneficial effects that the connecting film, the second opening and the strip-shaped side opening are arranged, so that the second opening of the connecting film corresponds to the first opening in the film body, and the film body is firstly adhered to the ear of a patient, so that the ear penetrates out of the first opening; the connecting film is attached to the film body after being sleeved on the ear through the strip-shaped side opening, the design is tightly attached to the outline of the ear, flushing or perfusate permeation is effectively blocked, pollution of an operation area and discomfort of the ear of a patient are avoided, cleanliness and comfort of the ear operation are improved, and the postoperative infection risk is reduced.
Owner:亳州市人民医院

Operating table with temperature control function

The operating table with the temperature control function comprises a bed frame, the bed frame at least comprises a head pillow section, a back pillow section and a leg pillow section, each area is provided with a first temperature sensor for monitoring the temperature and a temperature control structure for adjusting the temperature, and each temperature control structure comprises a heating mechanism and a cooling mechanism. The operating table further comprises a control system capable of receiving signals of the first temperature sensors so as to control the corresponding temperature control structures to adjust the temperature. Accurate temperature control can be carried out according to different surgical sites, for example, different surgical requirements that neurosurgery needs head low temperature, abdominal surgery needs trunk constant temperature and the like. Compared with a traditional single global temperature control scheme, the local overheating or supercooling risk is effectively avoided, and the intraoperative complications and the postoperative infection rate are remarkably reduced.
Owner:ZHONG SHAN PEOPLES HOSPITAL

Medical movable bath tent

The utility model discloses a medical movable bathing tent, relates to the related field of medical bathing, and aims to solve the problems that in existing medical facilities, a patient cannot obtain timely and appropriate bathing service, the risk of postoperative infection is increased, and the rehabilitation speed of the patient is possibly affected. A bathtub structure is arranged in the middle of the upper end of the heat preservation supporting bottom plate. A water storage tank is arranged at one end of the upper end of the fixed bottom plate, a conveying pump is installed at the upper end in the water storage tank, the output end of the conveying pump is connected with a shower pipe, a drainage tank is arranged at the other end of the upper end of the fixed bottom plate, a water pump is installed at the front end of the drainage tank, and the output end of the water pump is connected with a second conveying pipe. The other end of the second conveying pipe extends into the drainage tank; a supporting framework and an outer heat preservation tent body are arranged at the upper end of the heat preservation supporting bottom plate along the exterior of the bathtub structure, and the outer heat preservation tent body is located outside the supporting framework.
Owner:COMMUNITY HEALTH SERVICE CENT OF NANJING EAST ROAD STREET HUANGPU DISTRICT SHANGHAI

Calculus taking-out device for hepatobiliary surgery

The invention relates to the technical field of medical instruments, in particular to a calculus taking-out device for hepatobiliary surgery, which comprises a sleeve, a net bag structure is mounted at one end of the sleeve, a driving assembly is mounted at the other end of the sleeve, the net bag structure comprises a bag body and a distraction assembly, and the distraction assembly comprises a fixing component and a transmission component; a partition plate is fixedly connected to the middle of the inner wall of the sleeve, a through groove is formed in the partition plate, a mounting frame is arranged on one side of the partition plate, a lead screw is rotationally matched with the mounting frame, the lead screw is in threaded connection with a nut seat, the nut seat is fixedly connected with a push block, a push rod is fixedly connected to one side of the push block, and the push rod penetrates through the through groove to be fixedly connected with a side plate. The transmission part is mounted on the mounting plate; one end of the screw rod is rotationally matched with the mounting frame, and the other end is fixedly connected with the driving assembly. The calculus capturing efficiency is improved, bile duct wall injuries and postoperative infection risks are reduced, and the requirements of minimally invasive surgery for instrument accuracy, stability and safety are met.
Owner:THE AFFILIATED HOSPITAL OF GUIZHOU MEDICAL UNIV

Ultrasonic probe with drug delivery function

The utility model belongs to the technical field of medical equipment, and particularly relates to an ultrasonic probe with a drug delivery function, which comprises a bottom plate, a telescopic rod is fixedly connected to the top of the bottom plate, a circular plate is fixedly connected to the top of the telescopic rod, an ultrasonic debridement machine is mounted at the top of the circular plate, one side of the ultrasonic debridement machine is communicated with an ultrasonic delivery pipe, and the other side of the ultrasonic delivery pipe is communicated with a drug delivery pipe. The end, away from the ultrasonic debridement machine, of the ultrasonic conveying pipe is communicated with an ultrasonic probe body, one side of the ultrasonic debridement machine is fixedly connected with a water tank, a medicine conveying assembly is arranged on the water tank, a cleaning assembly is arranged in the water tank, and the medicine conveying assembly comprises a medicine injection pipe communicated to the top of the water tank; a water pump is fixedly connected to a shell of the ultrasonic debridement machine. Drug can be directly conveyed to an infected part through the probe, debridement can be helped, the anti-infection effect can be enhanced, the risk of postoperative infection is reduced, the recovery time is shortened, and the overall curative effect of a patient is improved.
Owner:BEIJING KEYI BANGN MEDICAL DEVICE TECH CO LTD +1

Hepatobiliary surgery patient rehabilitation process tracking method based on Internet of Things

The invention relates to the technical field of medical internet of things, in particular to a hepatobiliary surgery patient rehabilitation process tracking method based on the internet of things, which comprises the following steps: acquiring electrocardiosignals of a patient based on the internet of things to judge the trend consistency, extracting multiple physical sign records to construct a boundary linkage strength grade, analyzing the temperature gradient of a thermal inductance node to evaluate the postoperative infection risk. According to the method, the abnormal heat accumulation condition of an operation area is recognized by quantifying the direction consistency proportion of the electrocardiosignals, combining the boundary distribution characteristics of various parameters and utilizing the body surface temperature gradient inversion trend; a trajectory sequence is constructed by adopting a rehabilitation task completion proportion, trend analysis is performed in combination with time delay, and a compliance fluctuation risk is judged by using a task response interval change trend, so that multi-dimensional dynamic monitoring of a rehabilitation process is realized, the recognition sensitivity of an abnormal state is improved, and the tracking reliability of the rehabilitation process is enhanced.
Owner:TANGSHAN WORKERS HOSPITAL

Liquid metal composite hydrogel dressing and preparation method and application thereof

PendingCN122251665AEfficient broad-spectrum killing effectBroad-spectrum high-efficiency antibacterial propertiesAbsorbent padsBandagesOrthopedic departmentHydrogel matrix
The present application relates to the technical field of medical dressings, in particular to a liquid metal composite hydrogel dressing, a preparation method and application thereof.The liquid metal composite hydrogel dressing comprises a functional layer; the functional layer comprises a hydrogel matrix and gallium metal micro-nano droplets dispersed in the hydrogel matrix.The present application utilizes the characteristics that gallium metal micro-nano droplets can continuously release Ga 3+ in a moist wound environment, endows the dressing with efficient and non-drug-resistant broad-spectrum antibacterial ability, and the hydrogel matrix provides an ideal moist healing environment for the wound; the dressing has good biocompatibility, can effectively prevent and treat postoperative infections in orthopedics, and promote wound healing.
Owner:YUNNAN QUJING CENTRAL HOSPITAL (QUJING FIRST PEOPLES HOSPITAL)

Achilles tendon minimally invasive suturing instrument with high applicability

PendingCN121754241ASuture equipmentsRadiationConvalescenceOperating theatres
The invention discloses a high-applicability achilles tendon minimally invasive suturing instrument, and belongs to the technical field of achilles tendon minimally invasive instruments.The high-applicability achilles tendon minimally invasive suturing instrument comprises a U-shaped arm, universal devices are installed at the two ends of the U-shaped arm, outer side arms are movably arranged on the universal devices and fixedly connected with the universal devices through fixing screws, outer side rings are fixed to one ends of the outer side arms, and outer side rings are fixed to the other ends of the outer side arms. A sleeve is movably arranged on the outer side ring; a hinge device is arranged on the U-shaped arm, the hinge device is composed of an upper hollow sleeve and a lower hollow sleeve, the upper sleeve is connected with the U-shaped arm, two measuring rods are movably arranged in the lower sleeve, the two measuring rods are fixedly connected with the sleeves through fixing screw rods respectively, and oval forceps fixers are installed at the ends, away from each other, of the two measuring rods; the device is high in adaptability and accuracy, can be matched with any oval forceps in an operating room, is remarkable in minimally invasive property, greatly reduces tissue damage, reduces the postoperative infection rate, shortens the recovery period, and is adaptive to patient groups needing rapid recovery.
Owner:SHANXI LIMINGDA TECH CO LTD +1

Flushing device with splash-proof function for interventional operation

The utility model relates to the technical field of medical flushing, and discloses an interventional operation flushing device with a splash-proof function, which comprises a water storage device, the bottom of the water storage device is communicated with a water delivery pipe, one end of the water delivery pipe far away from the water storage device is communicated with a cleaning gun, and the left side of the cleaning gun is provided with a splash-proof mechanism. The right side of the water storage device communicates with a cleaning mechanism, the splash-proof mechanism is composed of a mounting assembly and a splash-proof assembly, the splash-proof assembly comprises a splash-proof cover, the inner wall of the splash-proof cover is rotationally connected with a rotating cover, the right side of the rotating cover is fixedly connected with a rubber ring, and the mounting assembly comprises a telescopic rod. And the right side of the cleaning gun communicates with a water spraying pipe. According to the utility model, through the structures such as the telescopic rod, the splash-proof cover and the water spraying pipe, liquid splashing generated when flushing liquid is sprayed to a surgical site is blocked, so that the splashing liquid is effectively prevented from carrying germs to diffuse, the pollution of a surgical area and the surrounding environment is reduced, and the possibility of postoperative infection of a patient is reduced.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Barrier membrane for guided bone regeneration and method for its production

PendingCN122272919ANanowireOsteoproliferation
This invention discloses a barrier membrane for guiding bone regeneration and its preparation method, relating to the field of materials technology for guiding bone regeneration. The barrier membrane comprises a stacked nanowire functional layer and a barrier layer, wherein the nanowire functional layer includes a Cu-loaded surface. 2+ Sr 2+ The barrier membrane, doped with hydroxyapatite nanowires, comprises polylactic acid as the barrier layer. This invention provides a barrier membrane that combines sequential ion release, directional ion release, immune regulation, angiogenesis promotion, osteoproliferation, and antibacterial adhesion functions, adapting to the stage-specific needs of bone repair and guiding bone regeneration. This invention effectively solves the problems of existing barrier membranes, which only provide physical barrier function, lack biological activity, are difficult to actively promote bone regeneration, have a single mode of active metal ion release, are difficult to achieve sequential regulation, have a high risk of postoperative infection, exhibit disordered diffusion of active components, and have limited functionality.
Owner:SHANDONG UNIV

A biodegradable spinal cage with osteoinductive microporous structure

The application discloses a degradable spinal fusion cage with a bone inductive microporous structure and belongs to the technical field of orthopedic implant medical devices. The fusion cage is integrally made of a degradable polymer composite material, the inside of the main body is provided with a bionic gradient microporous structure which is interconnected, and the surface of the fusion cage is provided with an active coating layer with a slow-release function. The mechanical property of the product is adapted to the physiological bearing requirement of the spine, the product can be steadily degraded along with the bone tissue regeneration process after being implanted into the human body, can effectively guide the bone tissue and microvessels to grow in, and can improve the intervertebral fusion efficiency; meanwhile, the problems of stress shielding, postoperative infection and the need for secondary removal surgery existing in traditional metal implants are solved, the product has good biocompatibility, the structure is reasonable, the preparation process is simple, and the product is suitable for clinical intervertebral fusion surgery of the spine.
Owner:李艳

Preparation and use method of radix sophorae flavescentis soaking and washing soup bag for patients with lower limb bone diseases before operation

The invention relates to a preparation and use method of a radix sophorae flavescentis soaking and washing soup bag for patients with lower limb bone diseases before an operation. The radix sophorae flavescentis soaking and washing soup bag for patients with lower limb bone diseases before operation comprises 30 parts of radix sophorae flavescentis, 30 parts of raw rhubarb, 15 parts of fructus gardeniae and 15 parts of rhizoma coptidis. The using method of the radix sophorae flavescentis soaking and washing soup bag for the patient with the lower limb bone disease before the operation comprises the following steps: step 1, putting the radix sophorae flavescentis soaking and washing soup bag into a pot, adding 1500ml of clear water, boiling with big fire, and decocting with small fire for 30-40 minutes; secondly, after decoction in the first step is completed, residues are removed, juice is taken and bagged for standby application, one bag comprises four bags, one bag is 100 ml, and the total volume is 400 ml; thirdly, when soaking and washing are needed, the patient is in the supine position, and the novel foot soaking device is used for soaking the foot on the side needing the operation. According to the device, the leg angle can be adjusted to meet the supine position requirement, and single-side soaking is achieved; according to the soaking and washing soup bag and the using method, the requirements of preoperative cleaning and disinfection of patients with lower limb bone diseases with different diseases can be met in a targeted mode, the postoperative infection risk is reduced through the drug efficacy and thermal action, and secondary damage caused during soaking and washing is avoided.
Owner:LUOYANG ORTHOPEDIC TRAUMATOLOGICAL HOSPITAL

Heart postoperative complication early warning system and method based on deep learning

The invention discloses a heart postoperative complication early warning system and method based on deep learning, and relates to the technical field of medical artificial intelligence, the system comprises a data acquisition module, a data preprocessing module, a feature extraction module, a feature fusion module, a complication prediction module and an early warning output module, the data acquisition module acquires electrocardiosignals, echocardiography images and vital sign data, the feature extraction module adopts a convolutional neural network to extract image space features and adopts a bidirectional long-short-term memory network to extract time sequence features, and the feature fusion module realizes multi-modal feature fusion through an attention mechanism. The complication prediction module predicts the occurrence probability of arrhythmia, low cardiac rejection syndrome, pericardial packing, postoperative infection and postoperative bleeding, the early warning output module carries out three-level early warning according to the probability value, continuous monitoring and early complication early warning on a cardiac postoperative patient are achieved, and the clinical nursing safety is improved.
Owner:THE FIRST AFFILIATED HOSPITAL OF ANHUI MEDICAL UNIV +1

Recyclable multifunctional hair collection skin preparation device

The invention relates to the technical field of medical instruments, and provides a recyclable multifunctional hair collecting and skin preparing device which is characterized by comprising a grab handle, a holding handle serving as the skin preparing device and a built-in power assembly serving as a power source, a negative pressure chamber is fixedly connected to the rear side of the front end of the grab handle, turbine fan blades are rotatably connected to the interior of the negative pressure chamber, and the turbine fan blades are connected to the rear side of the front end of the grab handle. And the power assembly is used for driving the cutting work of the skin preparation device and making the turbine fan blades rotate to produce negative pressure in the negative pressure chamber. According to the skin preparation device, only the hair of the surgical part of a patient is cut off, the skin is not scraped by a blade to remove the hair, the infection risk of the skin of the patient caused by scraping of the blade is reduced, repeated utilization of the skin preparation device and reasonable combination of disposable components are achieved through the modular design, the skin preparation device can be repeatedly used, and the cost is reduced. And the collected hair can be quickly discarded through a modularized disposable component, so that the preparation workload before and after an operation is reduced, and the postoperative infection risk is effectively reduced.
Owner:THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV

Pressure measuring sheath for percutaneous nephroscope

The pressure measuring sheath for the percutaneous nephroscope comprises a sheath tube body and a pressure measuring sensor, the pressure measuring sensor comprises a pressure measuring chip, a sensor guide wire and a pressure reader, the pressure measuring chip is arranged at one end of the outer wall of the sheath tube body, and a first through hole is formed in the end, close to the pressure measuring chip, of the wall of the sheath tube body. A second through hole is formed in the end, away from the pressure measuring chip, of the wall of the sheath tube body, the sensor guide wire is located in the sheath tube body, the first end of the sensor guide wire penetrates through the first through hole to be electrically connected with the pressure measuring chip, and the second end of the sensor guide wire penetrates through the second through hole to be electrically connected with the pressure reader. The pressure measuring chip is integrated at the tail end of the sheathing canal body, and is connected to the pressure reader through the sensor guide wire arranged in the sheathing canal body, so that the internal pressure of the renal pelvis can be detected in real time in an operation process; the stone breaking and removing efficiency in the percutaneous nephroscope operation process can be improved, the operation time is shortened, the internal pressure of the renal pelvis is controlled, and the risk of postoperative infection is reduced.
Owner:王大伟

Atomizer for preventing infection after hot steam operation and medicine suction monitoring method

The invention relates to the technical field of nebulizer medicine suction monitoring, in particular to a nebulizer for preventing hot steam postoperative infection and a medicine suction monitoring method. According to the method, clinical analysis of medicine suction pressure data in the medicine suction process is adjusted through the influence of the number of times of the real-time medicine suction process and the severity degree of respiratory diseases, and respiratory pressure abnormity judgment is conducted; the real-time local medicine suction effectiveness of the patient is obtained based on the relation between the leading-in efficiency of the real-time atomization pressure and the atomized medicine flow and the historical medicine suction process, then the effective abnormity of the patient is determined, abnormity warning is conducted, and the medicine suction amount is adjusted. According to disease information of a patient and real-time changes and deviations of medicine suction efficiency and pressure, the hot steam ablation action condition is analyzed, abnormity monitoring, timely alarming and medicine suction conditioning are carried out in the aspects of respiration intensity and medicine suction flow, the effectiveness of the atomization medicine administration process is ensured, and the effect of preventing hot steam postoperative infection is better.
Owner:SHENZHEN GUANGMING DISTRICT PEOPLES HOSPITAL (SHENZHEN GUANGMING SCI CITY HOSPITAL)

Anchoring mechanism and device for percutaneous interventional treatment of hydrocephalus

PendingCN122057151AWound drainsSubarachnoid spaceHydrocephalus
The invention relates to an anchoring mechanism and a device for percutaneous interventional therapy of hydrocephalus, the device comprises a shunting unit, the shunting unit comprises a shunting tube body, a one-way valve and an anchoring mechanism, the anchoring mechanism comprises a fixing part and an anchoring rod, one end of the anchoring rod is connected with the fixing part, the other end of the anchoring rod is a free end, and the anchoring mechanism is connected with the other end of the anchoring rod in an anchoring state. And the anchoring rod deviates relative to the fixed part, or the anchoring rod deviates from the shunting pipe body, so that a space for anchoring is formed. The invention provides a brand new anchoring mechanism which does not relate to an expansion structure, so that the volume of the device in the subarachnoid space can be reduced, and the intracranial occupation is reduced; the device can be used for treating hydrocephalus through an intervention method, open surgical operation is not involved, trauma is reduced during operation, surgical operation time is saved, the contact area of the device and blood is reduced, and therefore the risk of central nervous system injury and blood-related complications is reduced; and the possibility of postoperative infection can be greatly reduced by matching with an anchoring mechanism.
Owner:QINGZHOU MEDICAL TECHNOLOGY (SUZHOU) CO LTD

Precursor protein capable of expressing recombinant cat lactoferrin, nucleotide molecule, recombinant expression vector, stably transfected cell strain and construction method and application of stably transfected cell strain

The invention discloses a precursor protein capable of expressing recombinant cat lactoferrin (rfLF), a nucleotide molecule, a recombinant expression vector, a stably transfected cell strain and a construction method and application thereof, and relates to the technical field of recombinant protein expression. The amino acid sequence of the rfLF precursor protein comprises a heterologous secretion signal peptide and a mature fLF sequence as shown in SEQ ID NO: 1; the heterologous secretion signal peptide selects a sequence of a signal peptide OST1, INU1, SUC2, IGK1 or PPIB to replace a sequence of a leader peptide alpha-factor or a K28 alpha subunit, so that the secretion efficiency of the rfLF in a stably transfected cell strain can be remarkably improved. A recombinant expression vector containing an rfLF precursor protein gene, a CMV promoter, an SV40 terminator and a puromycin resistance gene is constructed, the recombinant expression vector is stably integrated into a CHO-K1Q cell genome in a multi-copy mode, and the stably transfected cell strain capable of efficiently and stably expressing the rfLF is obtained. The obtained rfLF has a cat specific glycosylation mode, and can be used for preparing drugs or products for preventing or treating cat stomatitis, stress soft stool and postoperative infection.
Owner:CHANGCHUN WEISHI TESTING TECH SERVICE CO LTD

Tibia drilling guider for posterior cruciate ligament repair

PendingCN121370302ABone drill guidesTibial bonePosterior cruciate ligament
The invention relates to the technical field of medical instruments, and discloses a posterior cruciate ligament repair tibia drilling guider which comprises a positioning frame, a positioning curet and a positioning rod. The positioning frame comprises an arc-shaped handle, an arc-shaped sliding rail and a guide handle are installed at the two ends of the arc-shaped handle respectively, the positioning curette is matched with the arc-shaped sliding rail, the position of the positioning curette on the arc-shaped sliding rail is adjustable, a through guide hole is formed in the guide handle, the positioning rod penetrates through the guide hole in a sliding mode, and a drilling channel for a bone drill to penetrate through is formed in the positioning rod. The guide handle is provided with a locking fastener for limiting one-way sliding of the positioning rod; and the end part of the positioning rod is sleeved with a sealing shaft. The positioning curette is inserted from a rear side incision, slides along the guide handle and is locked to complete tibia positioning, before drilling, the sealing shaft slides to form an annular sealing structure, blood is prevented from interfering with the surgical field, during drilling, sterilization liquid can be conveyed to the drilling position through the elastic piston part, sterilization is achieved, the influence of the external environment is reduced, and the operation efficiency is improved. The postoperative infection risk is reduced, and the operation quality and safety are improved.
Owner:ZHEJIANG UNIV

Graphene-modified antibacterial hernia patch composite screen cloth fabric and preparation method thereof

The invention discloses a graphene-modified antibacterial hernia patch composite screen cloth fabric and a preparation method thereof, and belongs to the technical field of surface modification of high polymer material fabrics. The fabric is composed of high polymer material multifilament woven mesh cloth and graphene modified on the fiber surface of the high polymer material multifilament woven mesh cloth. The preparation method comprises the following steps: firstly dissolving graphene oxide in a solvent to prepare a suspension, and then carrying out chemical reduction; then stranding two strands of high polymer material monofilaments to form multifilaments, and weaving the multifilaments into mesh cloth; and finally, under the inert gas atmosphere, the net cloth is arranged above the reduced mixed solution to be subjected to low-temperature fumigation treatment and dried. Graphene is firmly modified on the surface of the multifilament through a fumigation method, and the technological process is simple and controllable. Compared with a traditional monofilament fabric, the obtained multifilament fabric is softer, small in stress response after implantation, high in strength, good in durability and lasting and broad-spectrum in antibacterial function, and the postoperative infection risk is effectively reduced.
Owner:SHAOXING RES INST OF ZHEJIANG UNIV

Device for compressing femoral artery or femoral vein

ActiveCN223799803UTourniquetsFemoral arteryBandage
The utility model provides a device for compressing a femoral artery or a femoral vein. The device comprises a bandage, a compression plate, a rotating shaft, a moving piece and a compression belt. Wherein the hydrogel coating is arranged on the surface of the compression belt, the hydrogel coating can form adhesion and antibacterial protection effects, and the postoperative infection risk can be reduced. The compression belt can be pressed on the thigh of the patient through elastic tightening of the binding belt, and it is guaranteed that the compression body of the compression belt presses the puncture point. The rotating shaft drives the moving pieces on the two sides of the compression plate to move, so that the compression belt clamps the thigh, the compression belt is prevented from rotating around the thigh to enable the compression body to leave a puncture point, and it is ensured that the compression belt and the compression body are fixed for a long time after an operation and do not shift. Therefore, the femoral artery and vein compression hemostasis device is suitable for femoral artery or femoral vein compression hemostasis after minimally invasive intervention, integrates compression, antibiosis, healing promotion and comfort, can effectively solve the problems of hematoma, infection and the like in nursing after minimally invasive intervention, and has wide clinical application value.
Owner:KUNMING YANAN HOSPITAL (KUNMING CADRE NURSING HOME)

Coating composition for surgical electrode with electrocision temperature lower than 37 DEG C and surgical electrode

The invention discloses a coating composition for an operation electrode with the electric excision temperature lower than 37 DEG C and the operation electrode, and relates to the technical field of electrode coating curing paint. The invention relates to a coating composition for an operation electrode with an electrocision temperature lower than 37 DEG C. The antibacterial coating is prepared from the following components in parts by mass: 25 to 35 parts of epoxy resin, 15 to 25 parts of polyurethane resin, 5 to 10 parts of graphene, 3 to 8 parts of polytetrafluoroethylene powder, 2 to 5 parts of silicon dioxide nanoparticles, 1 to 3 parts of a silane coupling agent, 30 to 50 parts of an organic solvent and 1 to 2 parts of a long-acting antibacterial agent. In order to overcome the defects that an existing antibacterial coating is short in antibacterial time efficiency and prone to proceeding along with an operation or aging failure, the composite coating has long-acting antibacterial capacity, the antibacterial effect can still be well reserved even after multiple times of related aging treatment, the whole operation process can be better covered, and the postoperative infection possibility is reduced.
Owner:DONGYUE MEDICAL DEVICE (WUHAN) CO LTD

A postoperative infection risk early warning system for craniocerebral trauma patients

The application discloses a kind of postoperative infection risk early warning system of craniocerebral trauma patient.The system uses "multimodal perception-privacy computing-interpretable early warning-closed loop intervention" four-layer integrated architecture, including multimodal perception and fusion module, privacy computing hub module, interpretable early warning engine and intelligent closed loop intervention module connected in turn.Communication connection is integrated millimeter wave radar, flexible sensor array and MS@SLET sensor chip in multimodal perception and fusion module, realize multidimensional data high-fidelity acquisition;Privacy computing hub module is based on improved FlexFair federated learning framework, and data privacy protection and group prediction fairness are considered;Interpretable early warning engine realizes accurate early warning and generates structured attribution report by the CNN-Transformer hybrid model of stage perception attention mechanism;Intelligent closed loop intervention module realizes hierarchical early warning, individualized scheme matching and model incremental optimization.The application solves the bottleneck of the prior art, such as insufficient timeliness of early warning, imbalance between data utilization and privacy fairness, uninterpretable decision and early warning intervention fragmentation, shortens the infection index detection time to within 30 seconds, the system response time is less than 200 ms, the infection-related mortality rate is reduced by 65.4%, fully meets the requirements of laws and regulations such as "Personal Information Protection Law", and has very high clinical application value.
Owner:NANJING DRUM TOWER HOSPITAL