24 results about "Open wounds" patented technology

The invention belongs to the technical field of biomedical materials, and discloses a viola philippica exosome-loaded composite hydrogel as well as a preparation method and application thereof, the composite hydrogel is prepared by mixing methacrylated polylysine (PLMA), oxidized dextran (ODex), viola philippica exosome (V-E), a photoinitiator and a physiologically compatible solvent and performing illumination crosslinking; the preparation method comprises the following steps: respectively preparing PLMA and ODex solutions, extracting and purifying V-E, adding a photo-crosslinking agent (LAP), mixing the components to obtain a precursor liquid, and carrying out in-situ curing molding through ultraviolet-visible light irradiation. The composite hydrogel provided by the invention solves the problems that the existing wound dressing is difficult to fit with irregular wounds, is antibacterial and easy to resist drugs, and lacks active anti-inflammatory and efficient healing promotion capabilities, and is suitable for repair treatment of infectious open wounds such as burns, trauma, diabetic foot ulcer and postoperative infected incisions.

The present invention provides a use of a functional thylakoid extract, particularly in combination with a physiologically acceptable carrier, for medical purposes in wound healing. The thylakoid extract can be used to treat wounds in the skin or mucosa, such as open wounds or wounds caused by physical trauma. The thylakoid extract can be used to increase the production or level of GM-CSF growth factor and / or G-CSF growth factor in the skin or mucosa of a subject after wounding (e.g., wounds in the skin, mucosa, or corneal epithelium).

A method of expanding skin adjacent to an open wound according to the present disclosure includes steps of providing a first expanding device and a second expanding device; placing the first and second expanding devices on two opposite sides of the wound; coupling the first expanding device, the skin, and the second expanding device with a suture; expanding the skin by pulling the suture to bring the expanding devices toward each other, wherein the expanding devices distribute pulling forces from the suture over the skin and bring the skin toward each other; and releasing the suture to allow the skin to relax.

A method of expanding skin adjacent to an open wound according to the present disclosure includes steps of providing a first expanding device and a second expanding device; placing the first and second expanding devices on two opposite sides of the wound; coupling the first expanding device, the skin, and the second expanding device with a suture; expanding the skin by pulling the suture to bring the expanding devices toward each other, wherein the expanding devices distribute pulling forces from the suture over the skin and bring the skin toward each other; and releasing the suture to allow the skin to relax.

The invention relates to an insulin pump for supplying medicine through a magnetic control capsule robot. The insulin pump comprises an implantable main body and the magnetic control capsule robot which can be taken orally and is filled with an insulin medicament, the implantable main body comprises a sealed shell, and a magnetic control module, a puncture module, a storage and transportation module and a power supply module which are integrated in the sealed shell. When the magnetic control capsule robot arrives near the right curve of the colon of the right inferior belly along the digestive tract, the magnetic control module of the implantable main body adsorbs and fixes the magnetic control capsule robot through magnetism; the puncture module punctures a shell of the magnetic control capsule robot through a puncture needle to establish a medicine channel; the storage and delivery module extracts insulin in the magnetic control capsule robot through negative pressure and stores the insulin, and then the insulin is pumped into the abdominal cavity of a patient through the piezoelectric micropump. According to the intraperitoneal infusion system, long-term wound opening caused by traditional in-vitro infusion is avoided for a type I diabetes patient needing to continuously supply insulin in a mode of orally taking the magnetic control capsule robot, non-invasive and accurate intraperitoneal infusion of insulin is achieved, and the wound infection risk of the type I diabetes patient can be remarkably reduced.

A wound closure system and a method of reducing the size of an open wound are disclosed. A suture line is sutured through body tissue adjacent an open wound, the suture line sutured so as to pass into the body tissue at an entry point and exit at an exit point, the suture line including a plurality of barbs extending outwardly at an acute angle with respect to a surface of the suture line. A biasing member applies a continuous pulling force on the suture line for stretching the body tissue toward the open wound, wherein the biasing member is configured to take up any slack of the suture line during stretching of the body tissue and keep the suture line taut.

The invention discloses a cholate synergistic effect-based open wound medicine formula and a preparation method thereof, cholate and sodium chloride are subjected to high-pressure homogenization and grinding to nanoscale, acetic acid, water and alcohol are sequentially added, after pH is adjusted, terminal filtration is carried out through a 0.22-micron filter membrane, sterility is ensured, the formula can penetrate into a corium layer to inhibit inflammatory factors (such as TNF-alpha), and the open wound medicine has a good application prospect. And an epidermal cell migration signal (such as TGF-beta 1) is activated, so that the healing period is shortened to 8-10 days. The nano-scale dispersion improves the medicine permeation efficiency, the weak acid environment inhibits the formation of a gram-positive bacterium biofilm, and the eye drops are free of sensitization, are suitable for immunodeficiency patients and have auxiliary effects on haemorrhoids and eye diseases.

Disclosed is an artificial scaffold material for a wound applied to the wound in order to cure the wound while suppressing scarring in a living body. The scaffold material includes: a biomaterial having a property to which progenitor cells of myofibroblasts of the living body adhere; and an anti-fibrotic agent contained and retained in the biomaterial, the anti-fibrotic agent being gradually released from the biomaterial as the biomaterial dissolves in the living body. The wound includes at least one of an open wound and a closed wound in the living body. The anti-fibrotic agent has a low molecular weight, and inhibits the progenitor cells from differentiating into the myofibroblasts in the living body. The scaffold material for a wound is placed on a target surface of at least one of the wound surface of the open wound, the wound surface of the closed wound, and a portion of the surface of the living body where the closed wound is exposed, thereby allowing the anti-fibrotic agent to be locally administered to the target surface.

There is provided methods for insect control, including controlling myiasis, in animals by affixing to the animal an elastomeric band having infused or contained within an insecticide, an insect repellent, lidocaine, or any combination thereof. The insect control may be a dual-mode control and may be in respect of existing or impending open wounds, including open wounds caused by castration, tail docking, umbilical cord ligation, or dehorning of an animal. There is also provided methods for castration, docking, umbilical cord ligation, or dehorning of an animal with concurrent insect control. Also provided are elastomeric bands for insect control and methods for preparing such elastomeric bands.

The invention provides a detection device for an open wound. The detection device comprises a bottom plate (1); the laser module (2) is provided with at least one laser head, and the laser head is movably and rotatably arranged on the bottom plate (1) and used for emitting a detection laser signal to a to-be-detected part; the plurality of detection modules (3) are arranged on the bottom plate (1) and comprise a detection panel (301) and a plurality of photoelectric detectors (302) arranged on the detection panel; the receiving module is used for receiving returned feedback laser signals; the hemostasis laser module (4) is arranged on the bottom plate (1) and used for emitting hemostasis laser; and the signal processing module is in electric signal connection with the laser module (2), the plurality of detection panels (3) and the hemostasis laser module (4) through a communication module (9), determines the contour of a wound according to the frequency change between the detection laser signal and the feedback laser signal, and controls the hemostasis laser module (4) to emit hemostasis laser according to the contour of the wound.

The invention discloses an open wound flushing and dressing changing device and method for emergency treatment, and belongs to the technical field of flushing and dressing changing devices. A liquid separation barrel, a liquid separation barrel II and a liquid separation barrel III are correspondingly used with a flow dividing part I, a flow dividing part II and a flow dividing part III in a waste liquid collecting box; the bottom of the operation panel is communicated with the waste liquid collection box, and the three liquid separation and classification collection boxes are correspondingly communicated with the first flow dividing part, the second flow dividing part and the third flow dividing part, so that corresponding flushing liquid corresponds to the same waste liquid collection structure, and the functions of waste liquid classification and waste liquid flow dividing are achieved; the limiting frame on the outer side of the operation plate and the outer ring of the waste liquid collecting box are covered with waterproof pads used for preventing moisture and absorbing dirt, the waste liquid collecting box is of a flushing liquid collecting structure, one side of the waste liquid collecting box sinks inwards, and the three sides of the waste liquid collecting box protrude outwards, so that the function of preventing splashing and overflowing of sight can be achieved while the wound limb limiting function is achieved.

The invention provides an orthopedic plaster as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicines, the orthopedic plaster comprises frankincense, myrrh, Sichuan notopterygium root, eucommia ulmoides, rhizoma cyperi, ox's teasel root, safflower, angelica sinensis, radix curcumae, rhizoma atractylodis, radix saposhnikoviae, dipsacus root, radix aconiti, radix aconiti agrestis, rhubarb, ephedra, drynaria baronii, semen strychni, catechu, radix sophorae flavescentis, rosin, borneol and dragon's blood. The multiple components cooperatively intervene in multiple pathological links such as inflammatory response, pain conduction and tissue repair through different action ways, the fracture healing period can be shortened, hyperostosis can be treated, the postoperative infection incidence rate can be reduced, muscle atrophy caused by long-term bed lying can be relieved, the joint movement function can be improved, and analgesic drug dependence can be reduced; the method is suitable for treating open wounds with damaged skin integrity.

The present application provides a kind of hydrogel composition, hydrogel and its preparation method and purposes.The hydrogel composition includes: buffer system, the buffer system includes polyacid and biological buffer agent;And, gel component, the gel component includes plant polyphenol and sulfur-containing fatty acid compound;Wherein, the mass ratio of plant polyphenol and sulfur-containing fatty acid compound is 1:2-10, preferably 1:2.5~5.The hydrogel composition of the present application can be used to prepare hydrogel, the hydrogel has antibacterial, antioxidant, anti-radical and the like performance.And, the hydrogel also has good self-repairing performance, tissue adhesion and biocompatibility, is suitable for bacterial infection type wound, local hemorrhage and open wound healing.

The present disclosure is concerned with compositions comprising insulin and a pharmaceutically acceptable topical carrier. The present disclosure is also concerned with methods of using these compositions for the treatment of a skin ailment such as a diabetic ulcer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Provided is a method for detecting information for measuring a biomolecule in which noise in a detection result can be suppressed when detecting information about light emitted on a living body and measuring the biomolecule on the basis of the detection result. The method for detecting information for measuring a biomolecule includes: emitting light on epidermis (7) of a secondarily-cured open wound in a living body (6); and detecting information about the light emitted on the epidermis (7).

The application relates to the technical field of medical instruments, in particular to a medical dressing for large-area wound treatment, which comprises a protective layer adhered to a wound and a closing mechanism arranged in the protective layer and used for closing the wound, wherein the closing mechanism comprises a pair of fixed patches symmetrically adhered to two sides of the wound, the length direction of the fixed patches is arranged along the length direction of the wound, a plurality of closing blocks are uniformly arranged on the fixed patches along the length direction, and a tensioning line used for tightly closing the skin on the two sides of the wound is connected to the two closing blocks oppositely arranged on the two fixed patches. The application has the effect of improving the treatment effect of the medical dressing on open wound treatment.

The invention belongs to the technical field of medical apparatus and instruments, and provides a hemostasis device for open wounds of maxillofacial regions, which comprises an adhesive patch, a plurality of air bag groups, a pressure patch, an air supply component, a plurality of electromagnetic switches and a control chip, each air bag group comprises a plurality of air bags which are closely arrayed and communicated, an air inlet is formed in one air bag, the pressure patches are pasted on the air bags in a one-to-one correspondence mode, an air outlet pipe of the air supply component is communicated with the air inlets in the air bag groups, and the electromagnetic switches are arranged on the air outlet pipe in a one-to-one correspondence mode. The control chip is fixed to the non-sticky side of the sticky patch and is in communication connection with the electromagnetic switch and the pressure patch. According to the invention, continuous manual compression by medical personnel is not needed, the edge area of the wound can be automatically identified and targeted compression can be performed, and secondary injury easily caused when a patient is transferred in a traditional hemostasis mode is avoided.

This invention discloses a synergistic active and passive antibacterial and healing-promoting dressing, its preparation method, and its application, belonging to the field of burn dressing technology. The technical solution is as follows: the dressing is a dopamine-sodium alginate-zinc ion composite functional dressing based on short-cycle, cyclic cross-linking coating technology. The preparation method includes the following steps: 1) compounding dopamine with polyurethane sponge; 2) short-cycle, cyclic cross-linking of sodium alginate and zinc ions to form a gelled coating; 3) drying the cross-linked dressing to obtain the synergistic active and passive antibacterial and healing-promoting dressing. This invention obtains a synergistic active and passive antibacterial dressing through short-time, multiple-cycle cross-linking technology, achieving a highly efficient antibacterial effect that integrates active and passive antibacterial principles. It also achieves multiple functions, including absorbing exudate and promoting healing, and is suitable for the production and application of dressings for open wounds such as burns and scalds.

The utility model relates to the technical field of outdoor medical supplies, and discloses an open wound hemostasis nursing bag which comprises an air bag cushion, a disinfection unit is arranged outside the air bag cushion, a debridement unit is arranged outside the air bag cushion, and a pressing function part is arranged outside the air bag cushion. The disinfection unit comprises a laying pocket which is fixed outside the air bag cushion and used for containing disinfectant, a disinfection bag extending to the outside of the laying pocket is arranged on the inner side of the laying pocket, and a liquid outlet valve is arranged on the side, located outside the laying pocket, of the disinfection bag; the debridement unit comprises a debridement pocket which is fixed outside the air bag cushion and is used for debridement elements, and debridement cotton swabs are inserted into the debridement pocket; the pressing function part comprises an inflation balloon which is communicated with the air bag cushion and can inflate the air bag cushion. The open wound hemostasis nursing bag has the advantage that different degrees of treatment can be carried out according to the size of a wound under the outdoor condition.

This invention discloses a method for preparing and applying a quaternized chitosan-stabilized selenium nanoparticle composite hydrogel, comprising the following components: quaternized chitosan selenium nanoparticles, chitosan, collagen, and oxidized konjac glucomannan. The collagen solution has a concentration of 1% w / v, the chitosan solution has a concentration of 2% w / v, the oxidized konjac glucomannan solution has a concentration of 2.4% w / v, and the concentrations of quaternized chitosan selenium nanoparticles are 10, 20, and 50 μg / mL. The volume ratio of collagen, chitosan, and oxidized konjac glucomannan is 1:1:1. This antibacterial hydrogel combines chitosan, collagen, oxidized konjac glucomannan, and quaternized chitosan selenium nanoparticles, exhibiting excellent antibacterial properties. The hydrogel enables the slow and continuous release of selenium nanoparticles, prolonging the antibacterial action time and improving the antibacterial efficacy and duration. It also demonstrates excellent wound-healing capabilities and shows promising application prospects in the healing of open wounds.

The compound formulations for the treatment and administration of drugs in open wounds, closed wounds and skin graft donor site wounds consists of the following: bupivacaine, tranexamic acid, adrenaline and hydrogel in the form of solution, hydrogel amorphous or hydrogel sheets. The hydrogel form consists of main ingredient drugs combined with one or more of hydrogel-forming polymers selected from a group consisting of one or more combinations of carboxymethyl cellulose, gelatin and pectin. The method for treating wounds in patients consists of applying the compound formula to the wound. The wounds are selected from a group consisting of surgical wounds, injury wounds, chronic and burn wounds. The compound formula is applied to wounds in the form of solution, hydrogel amorphous or hydrogel sheets.

The invention discloses a barrel-shaped wound self-positioning and self-cleaning negative pressure oxygen therapy device, and relates to the technical field of negative pressure oxygen therapy, the barrel-shaped wound self-positioning and self-cleaning negative pressure oxygen therapy device comprises a purification bin, electric wheels are uniformly mounted at the bottom of the purification bin, a seat is fixedly mounted on the upper surface of the purification bin, and negative pressure bins are symmetrically arranged in the middle of the upper surface of the purification bin. A first air bag and a second air bag which are driven by an electric telescopic rod and a rotatable monitoring and cleaning assembly are combined, accurate positioning, self-adaptive negative pressure isolation and automatic cleaning of a wound are achieved, and meanwhile a sterilization light band on the inner wall of a negative pressure bin guarantees cleanliness of the wound surface and the interior of the bin; the vibration isolation protection mechanism buffers vibration through cooperation of a compression spring and a sliding block, a tray pressure controller achieves starting protection of negative pressure equipment, and cleaning sewage enters a purification bin through a flow guide groove to be purified. The device integrates the functions of moving, positioning, cleaning, monitoring and vibration isolation, the treatment flexibility, accuracy and safety are improved, and the device is suitable for treatment of difficult-to-heal wounds such as diabetic foot ulcer and open wounds.