40 results about "Open wounds" patented technology

The present invention relates to a method for treating or preventing pathogenic infections in a subject having Cystic Fibrosis, COPD, and / or an open wound. This method involves selecting a subject having Cystic Fibrosis, COPD, and / or an open wound and administering to the selected subject a ceramidase under conditions effective to reduce ceramide and to treat or prevent the pathogenic infection. The method also involves the use of a ceramidase in combination with other drugs to reduce infection, reduce ceramide, or improve lung function in Cystic Fibrosis, COPD, and / or open wound patients.

The invention belongs to the technical field of biomedical materials, and discloses a viola philippica exosome-loaded composite hydrogel as well as a preparation method and application thereof, the composite hydrogel is prepared by mixing methacrylated polylysine (PLMA), oxidized dextran (ODex), viola philippica exosome (V-E), a photoinitiator and a physiologically compatible solvent and performing illumination crosslinking; the preparation method comprises the following steps: respectively preparing PLMA and ODex solutions, extracting and purifying V-E, adding a photo-crosslinking agent (LAP), mixing the components to obtain a precursor liquid, and carrying out in-situ curing molding through ultraviolet-visible light irradiation. The composite hydrogel provided by the invention solves the problems that the existing wound dressing is difficult to fit with irregular wounds, is antibacterial and easy to resist drugs, and lacks active anti-inflammatory and efficient healing promotion capabilities, and is suitable for repair treatment of infectious open wounds such as burns, trauma, diabetic foot ulcer and postoperative infected incisions.

The present invention provides a use of a functional thylakoid extract, particularly in combination with a physiologically acceptable carrier, for medical purposes in wound healing. The thylakoid extract can be used to treat wounds in the skin or mucosa, such as open wounds or wounds caused by physical trauma. The thylakoid extract can be used to increase the production or level of GM-CSF growth factor and / or G-CSF growth factor in the skin or mucosa of a subject after wounding (e.g., wounds in the skin, mucosa, or corneal epithelium).

A method of expanding skin adjacent to an open wound according to the present disclosure includes steps of providing a first expanding device and a second expanding device; placing the first and second expanding devices on two opposite sides of the wound; coupling the first expanding device, the skin, and the second expanding device with a suture; expanding the skin by pulling the suture to bring the expanding devices toward each other, wherein the expanding devices distribute pulling forces from the suture over the skin and bring the skin toward each other; and releasing the suture to allow the skin to relax.

A method of expanding skin adjacent to an open wound according to the present disclosure includes steps of providing a first expanding device and a second expanding device; placing the first and second expanding devices on two opposite sides of the wound; coupling the first expanding device, the skin, and the second expanding device with a suture; expanding the skin by pulling the suture to bring the expanding devices toward each other, wherein the expanding devices distribute pulling forces from the suture over the skin and bring the skin toward each other; and releasing the suture to allow the skin to relax.

The invention discloses a pharmaceutical composition and application thereof. The pharmaceutical composition contains the following components: homoplantaginin and amikacin which are stored independently or in a mixed manner of more than two of the homoplantaginin and the amikacin. According to the composition disclosed by the invention, homoplantaginin and amikacin are combined for use, and the homoplantaginin and amikacin play a synergistic effect, so that open wounds infected by methicillin-resistant staphylococcus (MRSA) can be effectively treated, and the effects of resisting inflammation, resisting oxidation and promoting healing are achieved.

The present invention discloses a detachable limb debridement table, which comprises: two table panels, one end of which is connected to a connecting seat via a universal ball joint, the connecting seat being threaded with an adjustment screw, and the locking adjustment screw can be used to position the angle of the table panels, the bottom of the connecting seat having a slot, the slot being buckled onto the side rod of the operating table, the slot being connected to a locking screw for locking the position of the connecting seat; a support plate for supporting the patient's upper limb, the two ends of the support plate respectively having downwardly bent portions, the bent portions at both ends of the support plate respectively overlapping the outer edges of the corresponding side table panels; and a waste liquid bag, the two side wings of the bag opening at the top of the waste liquid bag respectively wrapping and detachably connected to the two table panels. The present invention is simple and portable, can solve the problem of debridement surgery for batches of open wound patients in the field, and can also be used for clinical emergency debridement surgery.

The invention relates to an insulin pump for supplying medicine through a magnetic control capsule robot. The insulin pump comprises an implantable main body and the magnetic control capsule robot which can be taken orally and is filled with an insulin medicament, the implantable main body comprises a sealed shell, and a magnetic control module, a puncture module, a storage and transportation module and a power supply module which are integrated in the sealed shell. When the magnetic control capsule robot arrives near the right curve of the colon of the right inferior belly along the digestive tract, the magnetic control module of the implantable main body adsorbs and fixes the magnetic control capsule robot through magnetism; the puncture module punctures a shell of the magnetic control capsule robot through a puncture needle to establish a medicine channel; the storage and delivery module extracts insulin in the magnetic control capsule robot through negative pressure and stores the insulin, and then the insulin is pumped into the abdominal cavity of a patient through the piezoelectric micropump. According to the intraperitoneal infusion system, long-term wound opening caused by traditional in-vitro infusion is avoided for a type I diabetes patient needing to continuously supply insulin in a mode of orally taking the magnetic control capsule robot, non-invasive and accurate intraperitoneal infusion of insulin is achieved, and the wound infection risk of the type I diabetes patient can be remarkably reduced.

A wound closure system and a method of reducing the size of an open wound are disclosed. A suture line is sutured through body tissue adjacent an open wound, the suture line sutured so as to pass into the body tissue at an entry point and exit at an exit point, the suture line including a plurality of barbs extending outwardly at an acute angle with respect to a surface of the suture line. A biasing member applies a continuous pulling force on the suture line for stretching the body tissue toward the open wound, wherein the biasing member is configured to take up any slack of the suture line during stretching of the body tissue and keep the suture line taut.

The invention discloses a cholate synergistic effect-based open wound medicine formula and a preparation method thereof, cholate and sodium chloride are subjected to high-pressure homogenization and grinding to nanoscale, acetic acid, water and alcohol are sequentially added, after pH is adjusted, terminal filtration is carried out through a 0.22-micron filter membrane, sterility is ensured, the formula can penetrate into a corium layer to inhibit inflammatory factors (such as TNF-alpha), and the open wound medicine has a good application prospect. And an epidermal cell migration signal (such as TGF-beta 1) is activated, so that the healing period is shortened to 8-10 days. The nano-scale dispersion improves the medicine permeation efficiency, the weak acid environment inhibits the formation of a gram-positive bacterium biofilm, and the eye drops are free of sensitization, are suitable for immunodeficiency patients and have auxiliary effects on haemorrhoids and eye diseases.

The invention relates to the field of traditional Chinese medicine health care, and discloses traditional Chinese medicine health care powder for conditioning shoulders, neck, chest, waist and legs and a use method thereof.The use method comprises the following steps that S1, raw materials are prepared, specifically, 20 g of traditional Chinese medicine health care powder and 40 g of plain boiled water at the temperature of 40-45 DEG C are prepared; s2, blending with plain boiled water: stirring and mixing the plain boiled water and the traditional Chinese medicine health-care powder; s3, spreading the ointment liquid on the arthralgia part: spreading the ointment liquid on the arthralgia part by using a spreading tool through medical staff, and meanwhile, paying attention to avoiding an open wound or an eczema area. Through the unique traditional Chinese medicine formula combination, targeted conditioning of different types of shoulder, neck, chest, waist and leg problems is achieved. The basic formula of the first embodiment of the invention contains safflower, Chinese angelica and other medicinal materials, has the effects of basically promoting blood circulation to remove blood stasis and warming channels and expelling cold, is suitable for soreness and swelling of shoulders, neck, waist and legs caused by chronic strain and effectively relieves related symptoms, and experiments prove that the pain relieving effective rate of the traditional Chinese medicine composition on chronic strain type patients reaches 78.3%.

The invention discloses an active and passive synergistic antibacterial and healing-promoting dressing as well as a preparation method and application thereof, and belongs to the technical field of burn dressings. According to the technical scheme, the dressing is a dopamine-sodium alginate-zinc ion composite functional dressing based on a short-period and cyclic cross-linked coating technology. The preparation method comprises the following steps: 1) compounding dopamine and polyurethane sponge; (2) sodium alginate-zinc ions are subjected to short-period, cyclic and repeated cross-linking, and a gelation coating is formed; and (3) drying the crosslinked dressing, so as to obtain the active and passive synergistic antibacterial and healing-promoting dressing. The active and passive synergistic antibacterial dressing is prepared through a short-time multi-cycle cross-linking technology, the efficient antibacterial effect integrating active and passive antibacterial principles is achieved, meanwhile, the multiple functions of absorbing seepage and promoting healing are achieved, and the active and passive synergistic antibacterial dressing is suitable for production and application of dressing related to open wounds such as burns and scalds.

Disclosed is a treatment apparatus (100) for treatment of an open wound (OW) (102). The treatment apparatus comprises: processor (104), light source (LS) (106) and distance measurement device (DMD) (118) arranged to emit light (108) towards OW when in use, wherein DMD is 5 configured to measure distance between LS and OW. The processor is configured to control LS to emit: during first period (202) of time, light comprising first wavelength ranges (WRs), wherein first WR(s) is first disinfecting WR (DWR) of light (760) having first radiant power (RP); and during second period (204) of time, light comprising second WRs, wherein 10 second WR(s) is first disinfecting range having first RP a second DWR (762) of light having second RP, wherein first time period and second time period are between 30 to 90 seconds, and wherein each respective RP is RP of respective WR of light at open wound.

A method of expanding skin adjacent to an open wound according to the present disclosure includes steps of providing a first expanding device and a second expanding device; placing the first and second expanding devices on two opposite sides of the wound; coupling the first expanding device, the skin, and the second expanding device with a suture; expanding the skin by pulling the suture to bring the expanding devices toward each other, wherein the expanding devices distribute pulling forces from the suture over the skin and bring the skin toward each other; and releasing the suture to allow the skin to relax.

Methods are provided for insect control, including controlling fly maggot disease, in an animal by securing to the animal an elastic band impregnated or containing therein an insecticide, an insect repellant, lidocaine, or any combination thereof. The insect control may be dual mode control, and may be directed against existing or impending open wounds, including open wounds caused by castration, tagging, umbilical ligation, or chamfering of animals. Also provided are methods for castration, tail cutting, umbilical cord ligation, or chamfering of animals while insect control. Elastic bands for insect control and methods of making such elastic bands are also provided.

Disclosed is an artificial scaffold material for a wound applied to the wound in order to cure the wound while suppressing scarring in a living body. The scaffold material includes: a biomaterial having a property to which progenitor cells of myofibroblasts of the living body adhere; and an anti-fibrotic agent contained and retained in the biomaterial, the anti-fibrotic agent being gradually released from the biomaterial as the biomaterial dissolves in the living body. The wound includes at least one of an open wound and a closed wound in the living body. The anti-fibrotic agent has a low molecular weight, and inhibits the progenitor cells from differentiating into the myofibroblasts in the living body. The scaffold material for a wound is placed on a target surface of at least one of the wound surface of the open wound, the wound surface of the closed wound, and a portion of the surface of the living body where the closed wound is exposed, thereby allowing the anti-fibrotic agent to be locally administered to the target surface.

According to the technical scheme, the multifunctional medical external fixator comprises a soft silica gel plate, the soft silica gel plate is provided with a through hole, a notch and a mounting groove, and fixing grooves are formed in a plurality of corners of the soft silica gel plate; the elastic fixing band is provided with a plurality of fixing ends, fixing hooks are movably installed in the fixing ends, and the fixing hooks hook the fixing grooves so that the elastic fixing band can be connected with the soft silica gel plate; the dressing piece is detachably installed in the installation groove and makes contact with the human body, and auxiliary openings corresponding to the through holes and the notches in position are formed in the dressing piece. According to the fixator, the catheter can be firmly fixed through friction force of the soft silica gel plate, displacement or falling of the catheter is prevented, or emergency hemostasis is achieved, open wounds are protected and the like, meanwhile, the stress area is increased through the soft silica gel plate, and compression and damage to the skin of a patient can be reduced; the elastic fixing belt can prevent the fixator from being excessively tightened or rubbed, and irritation to the skin is reduced; the elastic fixing band is flexible in style and can be suitable for different parts of a patient; the fixator is simple in structure, convenient to operate and capable of improving working efficiency.

There is provided methods for insect control, including controlling myiasis, in animals by affixing to the animal an elastomeric band having infused or contained within an insecticide, an insect repellant, lidocaine, or any combination thereof. The insect control may be a dual-mode control and may be in respect of existing or impending open wounds, including open wounds caused by castration, tail docking, umbilical cord ligation, or dehorning of an animal. There is also provided methods for castration, docking, umbilical cord ligation, or dehorning of an animal with concurrent insect control. Also provided are elastomeric bands for insect control and methods for preparing such elastomeric bands.

There is provided methods for insect control, including controlling myiasis, in animals by affixing to the animal an elastomeric band having infused or contained within an insecticide, an insect repellent, lidocaine, or any combination thereof. The insect control may be a dual-mode control and may be in respect of existing or impending open wounds, including open wounds caused by castration, tail docking, umbilical cord ligation, or dehorning of an animal. There is also provided methods for castration, docking, umbilical cord ligation, or dehorning of an animal with concurrent insect control. Also provided are elastomeric bands for insect control and methods for preparing such elastomeric bands.

The invention provides a detection device for an open wound. The detection device comprises a bottom plate (1); the laser module (2) is provided with at least one laser head, and the laser head is movably and rotatably arranged on the bottom plate (1) and used for emitting a detection laser signal to a to-be-detected part; the plurality of detection modules (3) are arranged on the bottom plate (1) and comprise a detection panel (301) and a plurality of photoelectric detectors (302) arranged on the detection panel; the receiving module is used for receiving returned feedback laser signals; the hemostasis laser module (4) is arranged on the bottom plate (1) and used for emitting hemostasis laser; and the signal processing module is in electric signal connection with the laser module (2), the plurality of detection panels (3) and the hemostasis laser module (4) through a communication module (9), determines the contour of a wound according to the frequency change between the detection laser signal and the feedback laser signal, and controls the hemostasis laser module (4) to emit hemostasis laser according to the contour of the wound.

The invention discloses an open wound flushing and dressing changing device and method for emergency treatment, and belongs to the technical field of flushing and dressing changing devices. A liquid separation barrel, a liquid separation barrel II and a liquid separation barrel III are correspondingly used with a flow dividing part I, a flow dividing part II and a flow dividing part III in a waste liquid collecting box; the bottom of the operation panel is communicated with the waste liquid collection box, and the three liquid separation and classification collection boxes are correspondingly communicated with the first flow dividing part, the second flow dividing part and the third flow dividing part, so that corresponding flushing liquid corresponds to the same waste liquid collection structure, and the functions of waste liquid classification and waste liquid flow dividing are achieved; the limiting frame on the outer side of the operation plate and the outer ring of the waste liquid collecting box are covered with waterproof pads used for preventing moisture and absorbing dirt, the waste liquid collecting box is of a flushing liquid collecting structure, one side of the waste liquid collecting box sinks inwards, and the three sides of the waste liquid collecting box protrude outwards, so that the function of preventing splashing and overflowing of sight can be achieved while the wound limb limiting function is achieved.

The invention provides an orthopedic plaster as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicines, the orthopedic plaster comprises frankincense, myrrh, Sichuan notopterygium root, eucommia ulmoides, rhizoma cyperi, ox's teasel root, safflower, angelica sinensis, radix curcumae, rhizoma atractylodis, radix saposhnikoviae, dipsacus root, radix aconiti, radix aconiti agrestis, rhubarb, ephedra, drynaria baronii, semen strychni, catechu, radix sophorae flavescentis, rosin, borneol and dragon's blood. The multiple components cooperatively intervene in multiple pathological links such as inflammatory response, pain conduction and tissue repair through different action ways, the fracture healing period can be shortened, hyperostosis can be treated, the postoperative infection incidence rate can be reduced, muscle atrophy caused by long-term bed lying can be relieved, the joint movement function can be improved, and analgesic drug dependence can be reduced; the method is suitable for treating open wounds with damaged skin integrity.

The present application provides a kind of hydrogel composition, hydrogel and its preparation method and purposes.The hydrogel composition includes: buffer system, the buffer system includes polyacid and biological buffer agent;And, gel component, the gel component includes plant polyphenol and sulfur-containing fatty acid compound;Wherein, the mass ratio of plant polyphenol and sulfur-containing fatty acid compound is 1:2-10, preferably 1:2.5~5.The hydrogel composition of the present application can be used to prepare hydrogel, the hydrogel has antibacterial, antioxidant, anti-radical and the like performance.And, the hydrogel also has good self-repairing performance, tissue adhesion and biocompatibility, is suitable for bacterial infection type wound, local hemorrhage and open wound healing.

The present disclosure is concerned with compositions comprising insulin and a pharmaceutically acceptable topical carrier. The present disclosure is also concerned with methods of using these compositions for the treatment of a skin ailment such as a diabetic ulcer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

The invention belongs to the technical field of hemostatic materials, and particularly relates to a double-crosslinking injectable photo-thermal hemostatic hydrogel and a preparation method and application thereof.The preparation method includes the following steps that phenyl 2, 4, 6-trimethylbenzoyl lithium phosphate serves as a photoinitiator, methacrylated gelatin, aldehydelated hyaluronic acid and polydopamine serve as raw materials, and the double-crosslinking injectable photo-thermal hemostatic hydrogel is prepared through a hydrothermal method; the hydrogel is prepared through Schiff base bonds and ultraviolet crosslinking. The injectable hydrogel prepared by the invention can be injected into an internal hemorrhage part, or can be directly applied to open wound non-compressible hemorrhage after cross-linking is completed, and a rapid hemostasis effect is achieved through a photothermal effect.

Provided is a method for detecting information for measuring a biomolecule in which noise in a detection result can be suppressed when detecting information about light emitted on a living body and measuring the biomolecule on the basis of the detection result. The method for detecting information for measuring a biomolecule includes: emitting light on epidermis (7) of a secondarily-cured open wound in a living body (6); and detecting information about the light emitted on the epidermis (7).

The application relates to the technical field of medical instruments, in particular to a medical dressing for large-area wound treatment, which comprises a protective layer adhered to a wound and a closing mechanism arranged in the protective layer and used for closing the wound, wherein the closing mechanism comprises a pair of fixed patches symmetrically adhered to two sides of the wound, the length direction of the fixed patches is arranged along the length direction of the wound, a plurality of closing blocks are uniformly arranged on the fixed patches along the length direction, and a tensioning line used for tightly closing the skin on the two sides of the wound is connected to the two closing blocks oppositely arranged on the two fixed patches. The application has the effect of improving the treatment effect of the medical dressing on open wound treatment.

The invention belongs to the technical field of medical apparatus and instruments, and provides a hemostasis device for open wounds of maxillofacial regions, which comprises an adhesive patch, a plurality of air bag groups, a pressure patch, an air supply component, a plurality of electromagnetic switches and a control chip, each air bag group comprises a plurality of air bags which are closely arrayed and communicated, an air inlet is formed in one air bag, the pressure patches are pasted on the air bags in a one-to-one correspondence mode, an air outlet pipe of the air supply component is communicated with the air inlets in the air bag groups, and the electromagnetic switches are arranged on the air outlet pipe in a one-to-one correspondence mode. The control chip is fixed to the non-sticky side of the sticky patch and is in communication connection with the electromagnetic switch and the pressure patch. According to the invention, continuous manual compression by medical personnel is not needed, the edge area of the wound can be automatically identified and targeted compression can be performed, and secondary injury easily caused when a patient is transferred in a traditional hemostasis mode is avoided.

1. Name of the design product: Chest sealing patch. 2. Use of the design product: Used for treating open chest wounds, open chest wounds caused by penetrating chest injuries, and possible tension pneumothorax that may result. 3. Design key points of the design product: Lies in the combination of shape and pattern. 4. Picture or photo that best shows the design key points: Stereogram. 5. This design product is a thin product, and other views are omitted.