23 results about "Healing time" patented technology

The invention discloses a titanium-magnesium hollow screw system capable of promoting fracture healing and a manufacturing method. The titanium-magnesium hollow screw system comprises a titanium-based supporting structure and a magnesium filling layer. The titanium-based supporting structure comprises a main body part, the surface of the main body part is provided with an imitated bone trabecula part, and a plurality of bone gaps are formed in the imitated bone trabecula part; wherein bone gaps are filled with the magnesium filling layer, and the magnesium filling layer is combined with the titanium-based supporting structure in a physical embedding mode; the titanium-based supporting structure bears and maintains initial fixation and long-term bearing, so that the strength and the stability of the screw are ensured; the surface imitated bone trabecula and the communicated bone gaps increase the surface area and provide a physical channel for vascularization and bone tissue ingrowth, so that synostosis is promoted; the magnesium filling layer releases magnesium ions after being locally controllably degraded, so that osteogenesis and angiogenesis are favorably stimulated, the local biological environment is improved, instant mechanical support after an operation is ensured, bone healing is promoted through local biological activity release and structural orientation, the healing time is favorably shortened, and the healing quality is favorably improved.

Abstract Present invention discloses an oral ulcer patch which adheres to a surface of a mouth ulcer and reduces pain associated with the mouth ulcer while at the same time accelerating healing of the mouth mucosa. The oral ulcer patch comprises an anti-inflammatory agent, an analgesic agent; a healing agent; an agent that forms a protective barrier upon reacting5 with saliva in the mouth, wherein the patch adheres to the moist ulcer area inside the mouth, forms a protective barrier, releases active analgesic and anti-inflammatory agents, and wherein the application of the patch to the ulcer reduces the pain caused by the ulcer and reduces the healing time of the ulcer. 10 Abstract Present invention discloses an oral ulcer patch which adheres to a surface of a mouth ulcer and reduces pain associated with the mouth ulcer while at the same time accelerating healing of the mouth mucosa. The oral ulcer patch comprises an anti-inflammatory agent, 5 an analgesic agent; a healing agent; an agent that forms a protective barrier upon reacting with saliva in the mouth, wherein the patch adheres to the moist ulcer area inside the mouth, forms a protective barrier, releases active analgesic and anti-inflammatory agents, and wherein the application of the patch to the ulcer reduces the pain caused by the ulcer and reduces the healing time of the ulcer. 10 20 24 28 71 87 23 D ec 2 02 4 2 0 2 4 2 8 7 1 8 7 2 3 D e c 2 0 2 4 A b s t r a c t 5 1 0

The invention discloses a healing promoting agent for melon vegetable grafted seedlings. The healing promoting agent contains abscisic acid and ribulose phosphate. The effect of promoting communication of phloem and xylem of grafted seedlings can be achieved by spraying the healing promoting agent before grafting, the healing time of the melon vegetable grafted seedlings is shortened, the operation of film uncovering and film covering in the healing period is reduced, the healing period management is simplified, and the healing cost is reduced.

This invention discloses a device and method for detecting wound healing status and predicting healing time. The device includes a flexible substrate on which a photoelectric detection area and a light source area surrounding the photoelectric detection area are formed; a photoelectric detection array disposed within the photoelectric detection area, the photoelectric detection array including at least one organic photodetector; multiple light sources disposed within the light source area and spaced circumferentially thereon, each light source having its emitting surface facing the photoelectric detection area, for sequentially irradiating wound tissue located above the device with multiple preset wavelengths; a positioning area disposed on the upper surface of the flexible substrate, the planar projection of the positioning area on the flexible substrate at least partially overlapping the photoelectric detection area; at least one pressure sensor disposed within the positioning area; an angle sensor disposed on the flexible substrate and / or a circuit board below it; and a processing unit including a microprocessor integrating an analog-to-digital converter, a storage unit, and an embedded computing unit. This invention also discloses a related prediction method.

This invention discloses a piezoelectric sensing adaptive internal pressure fixation bone plate system for treating tibial plateau fractures, belonging to the field of orthopedic implantable medical devices. It includes a bone plate, pressure bolts, and an external control module. The bone plate is available in three specifications according to the Schatzker classification: lateral L-type, medial T-type, and bilateral composite type, with transverse internal pressure holes. The pressure bolts embed a PZT-5H piezoelectric sensing device and have an overload-resistant groove between the head and neck, enabling real-time acquisition of the compressive stress at the bolt-bone interface. The external control module transmits signals wirelessly via Bluetooth 5.0 and uses a PID algorithm to non-contactly drive the bolts via magnetic field coupling to adaptively adjust the compressive stress to 30–50 MPa. The system has two levels of safety protection: 55 MPa coil power-off protection and 80 MPa groove breakage protection. This system eliminates the need for secondary surgery, dynamically maintains optimal stress throughout the fracture healing cycle, with a healing time ≤12.5 weeks, a complication rate ≤4%, and an excellent / good knee HSS score rate ≥88%. It is suitable for Schatzker type I-VI tibial plateau fractures.

This invention discloses an integrated method and system for wound area recognition and recovery time prediction. Belonging to the interdisciplinary fields of medical image processing, artificial intelligence, and clinical nursing, this invention aims to solve the problems of low segmentation accuracy, subjective recovery time prediction, and low operational efficiency caused by the separation of wound recognition and recovery time prediction in traditional wound assessment methods. The key technical points are: employing optimized U-Net++ network technology to achieve accurate wound segmentation, then fusing multi-dimensional features with an XGBoost model to predict recovery time, and integrating image acquisition, processing, quantification calculation, and result output functions. This system is adaptable to various scenarios such as hospital clinical assessment and home nursing monitoring, providing objective and quantifiable assessment data for acute and chronic wounds such as trauma and pressure ulcers. Simultaneously, it achieves integrated processing of wound condition assessment and recovery prediction, significantly improving the accuracy and efficiency of nursing work.

The present invention relates an ion substituted bovine-derived hydroxyapatite (ion substituted BHA) with at least one type of ion selected from F, Si, Cl, carbonate, citrate, Na, K, Ag, Mn, Zn, Zr, Cu, Co, Fe, Au, B, Ba, Al, Bi, Mg or Sr, or combinations thereof. The modified BHA by ionic doping augments the strength and biocompatibility of the bone graft, reduces healing time, and have a minimal reaction in the body after surgery. The various aspects of the ion-substituted BHA of the present invention have been described along with the FIGS. 1 to 50. The present invention also relates to a process of preparing the ion substituted bovine-derived hydroxyapatite. The invention further relates to a scaffold comprising the ion-substituted bovine-derived hydroxyapatite.

The invention discloses a traditional Chinese medicine composition capable of accelerating fracture healing and application thereof, and belongs to the technical field of traditional Chinese medicine compounds. The invention solves the technical problem of how to provide the traditional Chinese medicine composition special for accelerating fracture healing. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 40 to 300 parts of rhizoma drynariae, 15 to 150 parts of roasted ground beeltle, 15 to 150 parts of frankincense, 35 to 300 parts of radix dipsaci, 35 to 300 parts of radix angelicae sinensis, 15 to 150 parts of ophisaurus harti, 30 to 300 parts of cortex acanthopanacis, 2 to 20 parts of hippocampus and 10 to 150 parts of calcined dragon bone. The technical effect of efficiently, simply, conveniently, economically and obviously shortening the fracture healing time is achieved.

The invention belongs to the field of biomedical materials, and particularly relates to a multifunctional dressing based on photoelectric conversion electrical stimulation and a preparation method of the multifunctional dressing. The preparation method comprises the following steps: doping drug-loaded MOFs into a coaxial electrospun shell layer, forming core-shell fibers with a core layer with light-driven in-situ electrical stimulation, and dispersing the core-shell fibers into dynamic disulfide bond cross-linked hydrogel to obtain the multifunctional dressing based on photoelectric conversion electrical stimulation. The dressing has an electrical stimulation effect and a relatively strong antibacterial effect on wounds under illumination, and can inhibit inflammation and promote healing of chronic wounds. By means of the dressing, the clinical healing time of the diabetic wound can be shortened to be within two weeks, and the dynamic hydrogel and the photoresponse design are matched with the complex microenvironment of the chronic wound.

The invention relates to a self-healing implementation method and device and electronic equipment, and the method comprises the steps: obtaining an alarm event of a unitized service system, extracting a first event attribute of the alarm event, and obtaining an event strategy set, each event strategy in the event strategy set being configured with a corresponding second event attribute, and under the condition that the first event attribute is matched with the second event attribute, determining a self-healing process corresponding to the target event strategy, and performing self-healing processing on the target business service according to the self-healing process. The method effectively makes up the defect that a traditional unitized architecture lacks a self-healing mechanism, remarkably reduces the dependence of fault processing on manual operation, shortens the fault recovery time, reduces the operation and maintenance cost and pressure, adapts to a complex scene of a privatized environment based on the characteristics of the unitized architecture, greatly improves the system stability and service continuity, and improves the user experience. And a powerful support is provided for reliable operation of enterprise-level applications in a privatized deployment mode.

The invention relates to the technical field of traditional Chinese medicine compositions, and discloses a traditional Chinese medicine composition for treating stress injury, a preparation method and foam excipients, the traditional Chinese medicine composition for treating stress injury comprises the following raw materials by weight: 4-10 parts of safflower, 15-20 parts of Chinese angelica, 13-17 parts of Radix Astragali, 3-5 parts of borneol, 3-7 parts of Rhizoma Bletillae, 2-6 parts of lithospermum and 12-14 parts of red peony root. The traditional Chinese medicine composition can remarkably shorten the healing time of the first-stage stress injury and reduce the morbidity of high-risk groups.

The invention discloses a fault self-healing and resource optimization method and system for a medical image SaaS platform, and the method comprises the steps: obtaining multi-source observation data in the operation process of the medical image SaaS platform, and constructing a digital twinborn model of the platform; based on the digital twinborn model and multi-source observation data, performing intelligent identification and root cause positioning on an abnormal state of the platform so as to execute cognitive analysis on a platform operation problem; and executing a preset corresponding fault repair operation and a resource optimization strategy according to the result of the cognitive analysis. The full-link transparency of the medical image SaaS platform is realized by constructing the digital twinborn model, the fault recovery time is greatly shortened, and the capabilities of the platform for automatically sensing, diagnosing and repairing system abnormity and adaptively optimizing resources are realized.

The application belongs to the technical field of biological medicine, and discloses a kind of pharmaceutical composition for oral mucositis and preparation method thereof.The pharmaceutical composition is composed of traditional Chinese medicine extract component 55~70wt% and chemical component 30~45wt%, traditional Chinese medicine extract component is composed of white and extract 30~44wt%, Huangqin extract 20~28wt%, Huangqi extract 15~22wt%, Huanglian extract 8~15wt%, borneol 3~5wt%, and chemical component is composed of sodium hyaluronate 25~38wt%, D-panthenol 22~30wt%, allantoin 18~25wt%, dipotassium glycyrrhizinate 15~22wt%.The traditional Chinese medicine extract component in the application follows the compatibility principle of monarch, minister, assistant and messenger, and has integrated treatment effect of anti-inflammatory, repair, pain relief and infection prevention after being matched with chemical component, can significantly reduce the level of inflammation factor of oral mucositis, and significantly shorten the healing time of oral mucositis.

The application discloses a kind of external formula for bacteriostatic anti-inflammatory and treating scald and preparation device thereof, including yellow wax 31.2 parts, camphor oil 40.2 parts, pearl powder 14 parts, sanqi powder 14 parts, phenol 0.3 parts, chloramine acid 0.3 parts, the yellow wax is royal jelly wax, the camphor oil is refined sesame oil, the pearl powder is nanoscale pearl powder, the sanqi powder is superfine sanqi powder, the phenol and chloramine acid are all medicinal grade raw materials;The bacteriostatic anti-inflammatory effect of external ointment prepared by the present formula is remarkable, the bacteriostatic rate of staphylococcus aureus, escherichia coli, pseudomonas aeruginosa and candida albicans is all ≥99.5%, and the bacteriostatic ring diameter is better than existing sulfadiazine silver ointment, while having good quick anti-inflammatory effect, accelerates the healing time of Ⅱ degree scald wound, reduces scar formation rate, while greatly reducing local irritation and allergic reaction, far lower than existing western medicine, with good wound healing and safety advantage.

The invention provides a biological dressing as well as a preparation method and application thereof. The preparation method comprises the following steps: thawing in still water; unhairing and degreasing; cutting and segmenting; fine trimming and punching; performing iodophor soaking treatment; soaking in purified water; soaking in a mixed solution of protease and alkali metal hydroxide; soaking in purified water; antibacterial agent brushing treatment is carried out; and packaging and irradiating. The product obtained by the invention can be used for purifying, cleaning and protecting wound surfaces, promoting granulation tissue growth, covering granulation wound surfaces, chronic ulcers and bedsores, shortening the healing time and improving the healing effect.

The invention discloses a postoperative recovery time determination method and device, equipment, a medium and a program product, and is applied to the technical field of artificial intelligence. The method comprises the following steps: acquiring user parameters of a user; the user parameters comprise physiological feature parameters used for representing the physiological state of the user, disease risk level parameters used for representing the disease of the user, operation related parameters, anesthesia related parameters and medical team ability evaluation parameters; the user parameters are input into an intraoperative anesthesia mode determining model, an intraoperative anesthesia mode output by the intraoperative anesthesia mode determining model is obtained, and the intraoperative anesthesia mode comprises a non-general anesthesia mode or a general anesthesia mode; according to the intraoperative anesthesia mode and the user parameters, the postoperative recovery time of the user is determined. According to the method, the postoperative recovery time of the user is determined through the user parameters of the user in multiple dimensions and the intraoperative anesthesia mode, and the problem that the accuracy is low when the postoperative recovery time of the user is predicted only through the physiological feature data in a single dimension can be solved.

The application relates to the technical field of medical imaging, and discloses a spine intervertebral fusion detection device and method based on deep learning, which aims to solve the problem of poor accuracy of existing intervertebral fusion detection methods, and mainly comprises the following steps: acquiring a spine image of a patient; performing image recognition and segmentation on the spine image based on a deep convolutional neural network model to obtain a first bone bridge image and adjacent upper and lower vertebral body images in the spine image; generating a spine healing image of the patient according to the first bone bridge image and the adjacent upper and lower vertebral body images and based on an adversarial generative network model, and determining a second bone bridge image in the spine healing image; determining the similarity of the first bone bridge image and the second bone bridge image, and determining the intervertebral fusion state of the spine of the patient according to the similarity. The application improves the accuracy of intervertebral fusion detection, can also predict healing trends and healing time, and is particularly suitable for patients after a spine fusion operation.

The invention relates to the technical field of medicines, in particular to a traditional Chinese medicine compound ointment for wound healing and a preparation method thereof. The traditional Chinese medicine compound ointment for wound healing comprises the following effective components: cortex pseudolaricis, radix et rhizoma rhei, flos carthami and radix salviae miltiorrhizae. According to the composition with the optimal ratio determined by the invention, all the medicines supplement one another, and a remarkable synergistic effect is generated. Experiments prove that the wound healing promoting effect of the traditional Chinese medicine compound ointment is obviously better than that of any single component and simple mixtures in equal proportion, and the healing time can be greatly shortened. The traditional Chinese medicine compound ointment can effectively improve the wound healing rate, promote tissue regeneration and inhibit inflammatory response.

The utility model provides a negative pressure suction and local hyperbaric oxygen therapy combined device, which relates to the technical field of medical treatment and comprises a rescue box, a partition plate is fixedly connected inside the rescue box, and the inside of the rescue box is partitioned by the partition plate. The second collecting frame and the negative pressure suction machine body are combined in the rescue box, the problems of wound debridement and oxygen deficit can be solved at the same time, bacteria, toxins and wound necrotic tissue in seawater can be effectively removed for a wound soaked in the seawater and a chronic wound infected by anaerobic bacteria, and the wound debridement and oxygen deficit can be effectively removed for the wound soaked in the seawater and the chronic wound infected by anaerobic bacteria. Compared with a pure NPWT or TOT technology, the negative pressure suction machine has the advantages that the cure rate is greatly increased, the healing time is shortened, certain portability can be achieved due to the fact that the second collecting frame and the negative pressure suction machine body are combined in the rescue box, and when a user uses the negative pressure suction machine, the negative pressure suction machine can be conveniently used by the user. And the device can be quickly moved.

This invention belongs to the field of suture technology, specifically relating to a drug-loaded suture and its preparation method. The drug-loaded suture provided by this invention includes a matrix and a drug loaded on the surface of the matrix; the matrix has a core-skin structure, the core layer of the matrix being polylactic acid filaments; the skin layer of the matrix is ​​a nanofiber membrane, the nanofiber membrane being composed of polycaprolactone and polyglycolic acid; the polyglycolic acid accounts for 10-90% of the mass percentage of the nanofiber membrane. The skin layer of the drug-loaded suture provided by this invention is prepared from two biodegradable materials with different degradation rates, polycaprolactone and polyglycolic acid. By limiting the ratio of polycaprolactone and polyglycolic acid in the skin layer, this invention can control the degradation cycle and drug release cycle of the drug-loaded suture, thereby adapting to different types of wounds with different healing times. Simultaneously, the core-skin structure of the drug-loaded suture provided by this invention provides excellent mechanical properties.

The invention relates to the technical field of biomedical materials, in particular to a double-response MXene / HAP composite material and a preparation method and application thereof. According to the preparation method, the amide regulating agent is introduced, the hydroxyapatite is induced in situ on the surface of MXene to grow in a preferred orientation mode in the crystallographic c-axis direction, effective control over the orientation structure of the hydroxyapatite is achieved, and therefore the piezoelectric response performance of the hydroxyapatite under low-intensity ultrasonic stimulation is remarkably enhanced; the near-infrared light absorption and conduction characteristics of MXene enable the composite material to generate synergistically amplified physical signals under the action of light stimulation and sound stimulation, the material can dynamically adjust the cell function state in a biological microenvironment under a mild external field condition, and the functional response efficiency is remarkably improved while good biocompatibility is guaranteed; and dynamic sequential regulation and balance of the immune microenvironment are facilitated, so that the immune repair and bone repair efficiency is improved, and the healing time is shortened.

The invention discloses a fault prediction and self-healing method and system for intelligent operation and maintenance of an e-commerce platform, and relates to the technical field of intelligent operation and maintenance of computers. The method comprises the following steps: collecting multi-dimensional heterogeneous telemetry data, carrying out space-time alignment by utilizing a link tracking identifier, and constructing a unified feature vector containing service semantics and resource states; inputting the unified feature vector into a fault prediction model, and generating an early warning signal containing a fault type and a probability by analyzing a time sequence trend; in response to the early warning signal, matching a target self-healing strategy in a self-healing strategy library by using a causal inference logic; and finally, realizing closed-loop repair through an automatic arrangement interface execution strategy. According to the method, the data island problem is solved through multi-modal data alignment, the dynamic baseline or graph neural network is utilized to effectively distinguish the e-commerce large promotion flow and the system fault, the safety of the self-healing decision is ensured through a causal inference mechanism, the false alarm rate is remarkably reduced, and the fault recovery time is shortened.