146 results about "Secondary surgery" patented technology

The present invention relates to a corrosion-resistant high-toughness zinc-magnesium alloy implanting material capable of being absorbed by human body. The alloy material comprises 96-99.998 wt% of Zn and 0.002-4 wt% of Mg. According to the present invention, the alloy material of the present invention is applied for the absorbable medical implant, particularly the vascular stent and the orthopedic implant (bone nail or bone plate and the like); the prepared zinc-magnesium alloy material of the present invention can be absorbed in the human body environment, such that the pain of the secondary surgery on the patient can be avoided; the corrosion resistance of the prepared zinc-magnesium alloy material is much higher than the corrosion resistance of the magnesium alloy, the degradation speed is substantially reduced, and the long-term mechanical support can be provided, such that the failure of the vascular stent, the bone nail and other implants in advance can be avoided; and the mechanical strength of the prepared zinc-magnesium alloy material is much higher than the mechanical strength of the polymer, and the prepared zinc-magnesium alloy material has characteristics of high toughness, easy manufacturing, good elastic modulus matching with human body, and simultaneous high corrosion resistance and high toughness achieving.

The invention discloses a vena cava filter. The vena cava filter comprises a filtering part, a binding part and a combining part, wherein the filtering part is arranged in the mode that the filtering part partially abuts against the inner wall of the vena cava; the binding part is made of biodegradable materials and is arranged in the mode that the binding part is connected with the filtering part at multiple positions and binds the filtering part; the combining part is arranged in the mode that the adjacent positions of the filtering part are connected with one another. Before the binding part is degraded, the vena cava filter is bound by the binding part to be of a cutting structure suitable for cutting thrombus flowing through the vena cava, and after the binding part is completely degraded, the vena cava filter is transformed into a support structure suitable for supporting the vena cava. The vena cava filter can be transformed into the support structure from the cutting structure more accurately after a period of preset time. The vena cava filter has the advantages of a conventional vena cava filter, for example, the vena cava filter is arranged in a minimally invasive surgery, the pain of a patient is little, and the side effects are low. A secondary surgery caused by recovery of the filter is avoided, and the relevant cost and the pain of the patient are further reduced.

The invention discloses an in vivo degradable and absorbable metal encirclement device for bone fracture internal fixation, which consists of a single claw-shaped fixing part, or a plurality of claw-shaped fixing parts and connecting plates combined together alternately. The encirclement device is prepared from a degradable metal material. The encirclement device tightly encircles a bone fracture part through a fixed claw to realize engagement alignment of broken bones; the connecting plates of the encirclement device connect the claw-shaped fixing parts together to form a shape matched with that of a bone. When the bone fracture part is healed up, the connecting plates of the encirclement device are degraded gradually, and when the bone fracture part has the mechanical strength of a normal bone, claw-shaped fixing ends of the encirclement device lose the fixing effect, become fragments coated by muscles and fibrous tissues and finally are completely absorbed by an organism. On the premise of meeting the fixing effect of a magnesium alloy bone plate, the encirclement device can greatly improve the treatment effect of the magnesium alloy bone plate without using wedge-type fixing ends such as magnesium alloy bone pegs and the like, and simultaneously, the magnesium alloy bone plate is not needed to be taken out through a secondary operation, so that pains of the patient are alleviated and postoperative long-term risks of the patient are reduced.

The invention relates to a multilayer coaxial fibrous bone repairing material and a preparation method thereof, and belongs to the field of biological materials. The material is through an static spinning technology of biodegradable biodegradable aliphatic polyester and a natural polymer which have biocompatibility and are used as main raw materials through using a four-layer coaxial syringe needle. The fiber of the material has a multilayer coaxial structure, and an antibacterial and anti-inflammatory drug and an osteogenesis promoting drug can be added according to the bone repairing processat different levels. The material has an excellent biocompatibility and a controllable long-term drug release property. The drugs loaded in the fiber are released layer by layer with the proceeding of the bone repairing process in order to provide required corresponding substances for different bone repairing stages. The material can be controllably degraded in vivo as needed, so secondary surgery for taking out the material is avoided.

The invention relates to a degradable fiber-enhanced polycaprolactone degradable bone nail and a preparation method thereof through a solution method. The bone nail is a nail-shaped object and comprises degradable fibers and polycaprolactone resin, wherein the degradable fibers are dispersed in the bone nail. The preparation method comprises the following steps of: (1) drying a high molecular material which can be absorbed by a human body and spinning into nascent fibers in a screw extruder in a molten mode, and drawing to obtain drawn fibers; (2) dissolving the polycaprolactone and an interface cosolvent in acetic ether to prepare a polycaprolactone solution; and (3) casting and pouring the polycaprolactone solution in a mould for a plurality of times, simultaneously adding the drawn fibers and removing the solvent; after the casting is finished, shaping the mould after the solvent is removed; and demoulding and performing lathe processing to obtain the bone nail. The degradable bone nail has high mechanical performance and bioavailability; the problem that the bone nail is required to be taken out through a secondary operation can be completely solved due to the degradability; the pain of a patient can be greatly relieved; the degradation period is adjustable; the preparation method is simple; and the bone nail is suitable for industrial production.

The invention relates to a preparation method of a bone restoration material containing multiple drug-loaded slow release systems, and belongs to the field of biomaterials. The preparation method comprises the following steps: adding an antibacterial medicine and halloysite nanotubes loaded with an osteogenesis promoting medicine through intracavity loading and tube outside grafting to main raw materials comprising biocompatible degradable aliphatic polyester and natural polymer, and carrying out an electrospinning technology to prepare the bone restoration material. The material has the advantages of excellent biocompatibility, controllable and long-term drug release performance, bone defect restoration promotion effect, no secondary surgery, and inhibition of bacterial infection and inflammations easily appearing after the defect.

The invention provides a biological protein flexible nanometer friction electric generator and a preparation method thereof. The preparation method comprises the steps of preparing a biological protein solution; providing a raster template, coating the surface of the raster template with the biological protein solution, and performing drying and separating to obtain a biological protein membrane with a micro-nano raster structure on the single surface; adopting a human body implantable metal as a target material, and sputtering a friction electrode layer on the surface, without the raster structure, of the biological protein membrane; and performing cutting, taking the biological protein membrane as a first biological protein layer and a second biological protein layer, and taking the friction electrode layer as a first metal friction electrode layer and a second metal friction electrode layer to form the biological protein flexible nanometer friction electric generator. The electric generator disclosed in the invention is totally formed by human body degradable materials, so that immunoreaction is not caused after the electric generator is implanted into human body, without takingout through a secondary surgery; and through the raster structure, completeness and reflection strength of a reflective pattern can be checked, so that the output power of the electric generator canbe fed back in real time, and the degradation condition of the biological protein flexible nanometer friction electric generator can be monitored.

The embodiment of the invention relates to an oral medical appliance, and discloses a protection structure of an alveolar bone defect bone grafting region. A protection structure of the alveolar bone defect bone grafting region comprises a shield film and retention pins, wherein the shield film is used for covering and sealing the alveolar bone defect bone grafting region; the retention pins are used for fixedly connecting the shield film and the jaw; a plurality of retention pins can be installed. The shield film and each retention pin are made of degradable alloy materials capable of being absorbed by the human body. Compared with the prior art, the shield film and the plurality of retention pins jointly provide stable regeneration space for the bone regeneration; the shield film and the retention pins can be slowly degraded and absorbed by the human body, so that the shield film and the retention nails can be gradually degraded and absorbed while protecting the alveolar bone defect bone grafting region; the bone tissue regeneration is promoted, so that the injury and the risk due to that fact that the shield film and retention pin are taken out by secondary operation can be avoided.

The invention relates to an aqueous humor drainage implant. The aqueous humor drainage implant comprises a T-shaped drainage tube and a drainage disk, which are connected, wherein a liquid inlet transverse tube of the T-shaped drainage tube has the same curvature radius as that of a limbus corneae; a drain groove is formed at the contact surface between the liquid inlet transverse tube and an aqueous humor; an aqueous humor outflow controller is formed by a drainage long tube of the T-shaped drainage wrapped along protuberant ridges of the drainage disk or by utilizing a double-leaf flap valve, so as to avoid or reduce the occurrence of shallow anterior chamber and ocular hypotension in early period of post operation; a liquid outlet end of the drainage tube is matched with an anti-fall off clamp on the drainage disk; the liquid inlet transverse tube and the drainage long tube are integrally formed, or abutted through a leak-proof clamp so as to reduce the cost of a secondary surgery and facilitate the replacement of the drainage tube when an operation fails due to blockage of the drainage tube; a 5-Fu lipidosome biological filtering membrane is attached to the inner wall of the drain groove so as to effectively control the formation of blood coagulation as well as the scarring of a surgical area; suture holes are formed at the front end of the drainage disk; and aqueous humor traffic holes are formed in the center of the drainage disk and the protuberant ridges are arranged at the periphery of the drainage disk. The novel aqueous humor drainage implant is applicable to the treatment of glaucoma, the volume of a filtering area is enlarged, and the drainage tube can be replaced, thereby reducing the difficulty of the secondary surgery.

The invention discloses an artificial four-branch elephant trunk blood vessel with a stent and components thereof. A main body blood vessel is divided into two parts. The first part is as follows: a flexural artificial blood vessel is designed according to the anatomical characteristics of an aortic arch of a human body, three branch blood vessels are divergent from the middle part on the side of a big bend, and one branch blood vessel is divergent from the side which is near to a small bend. The second part is as follows: a section of artificial blood vessel with a stent is designed, and artificial blood vessels without stents are respectively arranged on two sides of the stent for facilitating secondary operation. An outer sheath, an inner core and a cutting knife are additionally arranged for conveying and releasing the second part of the main body blood vessel. A fixing clamp is adopted for tightening a fixing ring for performing vascular anastomosis at the distal end of the aortic arch. The device is used for the operation of adding a stented elephant trunk and replacing an aortic arch, thus the number of anastomotic stomas can be reduced, the difficulty of the operation is reduced, and convenience is provided for the secondary operation.

The invention provides a removal-free temporary vena cava filter and a manufacture method thereof. A plurality of elastic support wires are arranged in the same direction by enclosing the same central axis; one end of each elastic support wire is collected and fixed on an end cap, and the other end of each elastic support wire is connected to a support ring, so that a cage-shaped structure with one end opened and the other end collected is formed; after the end cap which is made of a degradable material is degraded in a preset time, the metal wires in a collection region are restored by means of own elasticity, and attached to the vascular wall to form a structure similar to an intravascular stent, so that the vessel lomen can be completely opened, lumen inflammatory stenosis caused by the filter can be dilated, and the vascular wall is endothelialized; the metal wires supporting on the vascular wall can be embedded by the blood vessel, so that the lumen becomes smooth and clear; and only once venipuncture operation is required, and secondary surgery for taking out, and related complication and cost can be saved.

The invention discloses a preparation method of a silk fibroin material of composite nano-grade hydroxyapatite and application of the silk fibroin material in repairing bone fracture parts. The preparation method comprises the following steps: uniformly dispersing nano-grade hydroxyapatite into silk fibroin in a certain ratio, dissolving the nano-grade hydroxyapatite with hexafluoroisopropanol, pouring a mixed solution into a columnar mold, soaking with methanol, performing self-assembling regeneration on a silk fibroin molecular chain so as to obtain a composite material which is excellent inmechanical strength, and finally manufacturing medicinal bone nails from the composite material by using a mechanical processing method. According to the characteristics that the material is good inbiocompatibility, excellent in mechanical property and good in in-vivo degradation controllability, the silk fibroin material can be applied to bone fracture fixation. A silk fibroin/nano-grade hydroxyapatite composite bone fracture internal fixation material with in-vivo degradation controllability can be prepared by using a method which is simple and feasible, high in finished product rate and free of toxicity, osteoporosis symptoms caused in the bone fracture repairing process can be effectively avoided, and because of the characteristic that the material does not need to be taken out through a second time of operation, bone fracture patients can be relieved from pain.

The invention relates to a medicine carrying nanofiber membrane and preparation and application methods thereof. The medicine carrying nanofiber membrane is composed of polylactic acid-hydroxyacetic acid copolymer fiber, polydioxanone fiber and medicines, wherein the medicines are dispersed inside the polylactic acid-hydroxyacetic acid copolymer fiber. The preparation method of the medicine carrying nanofiber membrane comprises (1) mixing the medicines and polylactic acid-hydroxyacetic acid copolymer with solvent and then mixing polydioxanone with solvent to obtain two mixed solutions; (2) independently loading the two mixed solutions and performing electrostatic spinning with multi-spinneret electrostatic spinning equipment to obtain the medicine carrying nanofiber membrane. The obtainedmedicine carrying nanofiber membrane is prepared through electrostatic spinning and is stable in property, high in porosity and similar to extracellular matrices, and when applied to postoperative stumps, can be extracted without secondary surgery, be degradable in vivo and achieve linear release of the medicines.

The invention relates to a positioning marker made of degradable metal and a method for preparing the positioning marker. The positioning marker is made of pure magnesium or magnesium alloy. The totalcontent of impurities in the pure magnesium and the magnesium alloy is lower than 0.01% by mass fraction. At least three magnesium wires are woven to obtain the positioning marker. The positioning marker is provided with a wound end and a positioning end. The positioning end is connected to the wound end and is of a claw-shaped or anchor-shaped structure. The positioning marker and the method have the advantages that the tensile strength of the positioning marker is higher than 200 megapascal, the percentage elongation after fracture is higher than 10%, and the in-vivo degradation rate is lower than 0.5 mm/year; the positioning marker can be developed in ultrasonic and X rays, the locations of the positioning marker can be detected by the aid of ultrasonic or molybdenum target X rays in operative procedures and postoperative treatment procedures, and the positioning marker can be gradually degraded along with postoperative treatment, and can be absorbed by surrounding tissues or discharged from human bodies by means of metabolism without being taken out by means of second operation.

The present invention discloses a shower head type inter-dimensional decoupling two-dimensional wireless passive sensor, comprising a sensor bearing joint, an upper supporting cylinder, an upper showerhead rigid structure body, a rigid connecting circular plate, a curved rectangular bearing body, a curved rectangular variable ring, a lower showerhead rigid structure body, a torque deformation structure body, a curved rectangular transmission rod and a sensor bearing shaft. The shower head type inter-dimensional decoupling two-dimensional wireless passive sensor can simultaneously detect bending force component and torsion force component in coupling force, namely, structurally decouple the coupling force; does not need to be connected to a power supply line or collect data through a cableinterface; and can be applied in the medical field, and to streams of human implanted sensors, and greatly reduces steps for wire embedding or secondary surgery in a human body after the sensor is implanted into the human body.

The present invention provides a film-coated bioceramic artificial bone and a preparation method. The film-coated bioceramic artificial bone comprises a bioceramic artificial bone and a coating film wrapped on an outer surface of the bioceramic artificial bone; and a raw material for preparing the coating film is silk fibroin. The coating film on the artificial bone can effectively improve cell planting efficiency and adhesion ability of the artificial bone, at the same time avoids a bone nonunion phenomenon caused by periosteum defects, and effectively improves an osteogenic repair rate. Thecoating film is prepared by using the silk fibroin, the silk fibroin has no toxic effects on human body and can be hydrolyzed and degraded by proteases, degradation products have no toxic and side effects on tissues, and after the film-coated bioceramic artificial bone is used, no secondary surgery taking-out is needed, and pains of patients are reduced.

The invention relates to a completely-degradable net-shaped nasolacrimal stent. The completely-degradable net-shaped nasolacrimal stent comprises a sleeve-shaped net-shaped body made of biodegradable high polymer materials and provided with holes; a medicine coating is arranged on the surface of the net-shaped body; the net-shaped body is composed of a first net-shaped body part and a second net-shaped body part which are connected; in the compression state, the first net-shaped body part and the second net-shaped body part are the same in diameter; and in the expansion state, the diameter of the first net-shaped body part is larger than the diameter of the second net-shaped body part. After lumen rebuilding is completed, water and carbon dioxide are finally generated by the completely-degradable net-shaped nasolacrimal stent to be discharged through the nasal cavity; and second operations and pains of a patient are avoided. The nasolacrimal stent is suitable for approaching the body from the nasal cavity, so that injuries, caused by the fact that the nasolacrimal stent approaches the body from the positions above the eyes, to the lacrimal ductile and the nasolacrimal canal inner membrane are avoided. By means of the completely-degradable net-shaped nasolacrimal stent, the medicine slow release effect is achieved through the medicine coating; and continuous treatment on the nasolacrimal canal for a long time is accordingly achieved.

The invention discloses an intestinal anastomotic stoma protecting device which is used for supplying protection to the rectum after intestinal anastomosis surgery. The intestinal anastomotic stoma protecting device comprises a hollow elastic support part, a shielding cover which is connected with the elastic support part and provided with openings at the two ends and a traction part detachably connected with the elastic support part; when the intestinal anastomotic stoma protecting device is in the state of protecting an anastomotic stoma, the elastic support part is arranged at the far end of the anastomotic stoma, the shielding cover circumferentially shields the anastomotic stoma in the intestine, and the near end of the traction part penetrates through the shielding cover to be exposed out of a human body. According to the intestinal anastomotic stoma protecting device, the anastomotic stoma can be effectively protected and prevented from being polluted by excreta; in addition, after the physiological tissue of the anastomotic stoma grows well, the intestinal anastomotic stoma protecting device can be directly taken out without needing secondary surgery, convenience and rapidness are achieved, and secondary hurt cannot be caused to a patient.

The invention discloses a simultaneous planting guide plate device, which comprises a fixing plate and a planting guide plate, and the fixing plate and the planting guide plate are simultaneously installed and fixed in the oral cavity of the patient after transplanting bone to reconstruct the patient's jawbone or alveolar bone, and the fixing plate and the planting bone As well as the connection and retention of the healthy bone of patients on both sides of the grafted bone, at least one of the implant guide plate and the fixation plate or the healthy bone of the patient on both sides of the grafted bone is connected and retained. The simultaneous implantation guide plate device provided by the present invention can realize the simultaneous implantation of dental implants in the jaw bone or alveolar bone surgery of patients with transplanted bone reconstruction, thereby avoiding the need for later implantation of dental implants after bone graft reconstruction surgery. The second operation reduces the number of operations and the trauma to the patient's oral cavity.

The invention discloses a flexible intramedullary nail, which pertains to the technical field of orthopedic medical devices and aims at providing a flexible intramedullary nail which can spare secondary operation, eliminate stress shielding, promote fracture healing and has the advantages of simple structure, practicality and low cost. The technical proposal of the invention is that a nail pole of the intramedullary nail consists of a proximal-end nail body, a distal-end nail body and a spring body, wherein, the proximal-end nail body and the distal-end nail body are positioned at both ends of the nail pole respectively and a proximal-end fixed screw hole and a distal-end fixed screw hole are arranged on the two ends; the spring body is arranged in the middle of the nail pole and both ends of the spring body are tightly connected with the proximal-end nail body and the distal-end nail body respectively; the length and quantity of the spring body can be adjusted according to the characteristics of a long bone and the diameter of the spring body can be 2mm to 6mm and can be adjusted according to the requirements of fracture fixing. The flexible intramedullary nail has simple structure and innovative design, resolves the problems of eliminating stress shielding, promoting fracture healing, avoiding secondary operation, and the like after the intrameduallary nail is put in the body, and also has the advantages of simple structure, practicality and low cost.

A degradable rib fixator relates to a medical instrument, is adjustable in size, degradable in the human body, free of damage to bone mass, free of secondary surgery, simple in forming process, convenient in surgical operation and safe and reliable, and is provided with a center ridge plate and lateral fixing claws. A plurality of cylindrical holes are arranged at the center of the center ridge plate, and the lateral fixing claws are distributed on the left side and the right side of the center ridge plate. The tip end faces of the lateral fixing claws are circular preferably, and cross parts of the lateral fixing claws are arc-shaped. The center ridge plate and the lateral fixing claws are integrated by injection molding and are made of biomedical high-polymer poly-L-lactic acid with fine biological compatibility and degradable in the human body.

The invention provides an intelligent deformable method for an artificial prosthesis based on a shape memory polymer, and belongs to the technical field of medical equipment plastic surgery implants. The method solves problems that an existing plastic artificial prosthesis implantation process has large trauma, and adjusting prosthesis states again is difficult. The method comprises: 1, shaping an intelligent deformable prosthesis which has shape memory, and folding and compressing the prosthesis; 2, performing external stimulation to drive so the prosthesis is in a deformed unfolded state, to complete. The intelligent deformable prosthesis with shape memory is a shape memory polymer with good biocompatibility and physiological inert, and implantation wound is small, recovery process is fast, risk is low, and pain of a patient is reduced. If the patient is not satisfied on a plastic state, the intelligent deformable prosthesis can be driven to continue to deform and unfold through external stimulation, and deformation recovery rate of the prosthesis is controlled, to obtain deformation states in different degrees, until the patient is satisfied on the plastic state. The method prevents risks of a secondary surgery, and reduces pain of the patient.

The invention provides a positioning measuring device used for hip replacement surgery and a measuring method. Through the using of a high-precision sensor and a high-performance microprocessor to measure, the problems of manual error and body position error of rulers can be solved; and the measuring device can be installed and fixed on the anterior superior iliac spines of the hip pelvis of a patient with corresponding supporting tools to carry out measuring with the moving of the pelvis, and the patient is the measured target, so that the influences of patient standing positions on data canbe reduced. Through the measuring device and measuring method, surgery can be high in flexibility, for the specific conditions of the patient, surgical programs can be planned in advanced, so that suitable supine and lateral positions can be selected; and the data can be measured in real time during operation, through two-way data comparison and verification, better clinical curative effects can be achieved, and the probability of reoperation can be reduced. Based on a three-dimensional motion data model, the position plane of a human coronal plane can be accurately obtained according to three-dimensional motion data, so that the processing of angles can be more accurate.

The invention discloses a magnesium alloy sheet (strip)-reinforced absorbable intrabony fixing composite material and a preparation method thereof. The preparation method comprises the following steps of: dispersing and arranging magnesium alloy sheets or thin strips which are subjected to micro arc oxidation in an absorbable high molecular material serving as a substrate in an oriented way to enhance the mechanical performance of the absorbable composite material; mixing degradable polymer substrates such as poly(lactic acid) and the like with a magnesium alloy sheets or thin strip reinforced phase; manufacturing a bar and a plate by performing die pressing or extruding at the temperature of 80-235 DEG C under the pressure of 0.5-40 MPa; and performing subsequent machining to obtain various intrabony fixing products. The method has the characteristic of easiness in operating process conditions; a product has excellent mechanical performance, high biocompatibility, and safe, stable and controllable product degradation, is suitable for intrabony fixing products of various shapes, and has a wide market prospect; and pain of a patient caused by the need of secondary surgery or advanced failure of an orthopaedic fixing product.

The artificial pulmonary artery with valve includes one section of ox jugular vein with venous valve, and one or two sections of pipes made of artificial material and connected to the ox jugular vein. The artificial pulmonary artery with valve is coated with medical polymer material. The artificial pulmonary artery with valve is superior to available artificial pulmonary artery of ox jugular vein tissue alone, and the latter has the demerits of over reaction, over calcification, etc. The present invention has greatly improved long term treatment effect.