949 results about "Antibacterial coating" patented technology

The invention discloses a preparation method of an antibacterial self-repairing organic silicon coating, and belongs to the technical field of organic silicon resin preparation, octamethylcyclotetrasiloxane, siloxane and / or amino silane and a catalyst are sequentially added into a four-neck flask filled with nitrogen, after stirring and heating, acid treatment is performed to obtain amino polysiloxane with a quaternary ammonium salt modified side chain, and then the amino polysiloxane with the quaternary ammonium salt modified side chain is added into the four-neck flask to obtain the antibacterial self-repairing organic silicon coating. Adding carbon tetrachloride and methyl acrylate, adding sodium hydroxide after the reaction is finished, heating and refluxing, filtering to obtain a liquid product, carrying out rotary evaporation to obtain amino acid modified polysiloxane, uniformly stirring the amino acid modified polysiloxane and a solvent to obtain a component A, uniformly stirring an antibacterial cross-linking agent and a solvent to obtain a component B, stirring the component A and the component B, coating, and drying to obtain a finished product. And curing to obtain the amino acid modified polysiloxane for self-repairing the antibacterial coating. Through synthesis of amino acid modified polysiloxane, reversible crosslinking of polysiloxane is realized through chelation of amino and carboxyl on metal ions, the reversible crosslinking can be repeated for multiple times, and the metal ions have an antibacterial effect, so that the service life of the coating is prolonged.

The invention relates to the field of new materials, and discloses an antifouling and antibacterial coating material as well as a preparation method and application thereof, and the antifouling and antibacterial coating material comprises glycidyl methacrylate, a methacrylate betaine monomer and a methacrylate quaternary ammonium salt monomer. Compared with a release type antifouling and antibacterial coating, the antifouling and antibacterial coating material adopts a bionic technology, uses sulphobetaine as a functional group, is good in biocompatibility, does not contain toxic or heavy metal antibacterial agents, can ensure that the material is non-toxic for a long time, realizes eco-friendly long-acting antifouling and antibacterial effects, can be combined with a large number of water molecules, and has the advantages of being environmentally friendly and free of pollution. The coating contains quaternary ammonium salt monomers, forms a hydration layer on the surface, keeps certain biological inertness, reduces protein adsorption, contains the quaternary ammonium salt monomers, has excellent inhibition and killing effects on various bacterial infections, overcomes the problem that the coating is easy to fall off, and realizes firm bonding of the surface of the pipeline.

The invention belongs to the technical field of biological coatings, and provides an antibacterial coating with a TaCu nano multilayer structure and a preparation method of the antibacterial coating. The antibacterial coating comprises a Cu layer and a Ta layer which are sequentially and alternately stacked on a base body, the Cu layer is in contact with the base body, and the Ta layer is the outermost layer. The Cu layers and the Ta layers are sequentially and alternately stacked on the substrate, the Cu < 2 + > layer-by-layer release delays the release rate, the cytotoxicity is reduced, and a lasting antibacterial effect is obtained; meanwhile, due to introduction of Ta, the osteogenesis performance of the matrix is effectively enhanced, and proliferation of bone cells is promoted. The antibacterial coating does not show cytotoxicity to rat bone marrow mesenchymal stem cells, can inhibit growth of staphylococcus aureus for a long time, is beneficial to promoting proliferation of osteoblasts, and can be used as an antibacterial coating for the surface of a bone implant. The preparation method of the antibacterial coating provided by the invention has the advantages of simple process, high deposition speed and high bonding strength.

The invention discloses a portable wound surface protection brace and an application method thereof, and belongs to the technical field of medical instruments. The brace is of a cylindrical structure, is made of EVA materials, has flexibility, non-toxic characteristics and good supporting performance and is externally wrapped with cotton cloth and provided with ventilation through holes, high-density cotton strips are fixed to the two ends of the inner wall to form a hollow structure, and the circumference of the outer wall can be adjusted through at least three sets of bandages with hook-and-loop fasteners. And an antibacterial coating is added, so that clinical application is expanded. During application, a wound surface is subjected to liquid extraction and hydrogen peroxide cleaning in the earlier stage and then covered with insulin mixed normal saline gauze, and the dressing is prevented from making contact with clothes in cooperation with a brace; and smearing mupirocin ointment in the later stage and performing infrared irradiation, and continuously using the brace to keep the wound dry and zero contact. The brace can be repeatedly used, can adapt to various wound types and patient body types, effectively solves the problems of wound adhesion and friction in traditional nursing, creates a high-oxygen healing environment, remarkably shortens wound healing time, relieves pain of patients and improves life quality, and has good clinical application and popularization value.

The invention relates to the technical field of food packaging materials, in particular to a cerium dioxide nano-enzyme modified antibacterial coating and application of the cerium dioxide nano-enzyme modified antibacterial coating in food packaging. The biomimetic mineralization layer comprises the following components in percentage by weight: 35-45% of a green base material, 8-12% of dopamine modified yttrium-doped cerium dioxide nano-enzyme, 4-6% of a composite antibacterial agent, 3-4% of a natural cross-linking agent, 2-3% of a degradable plasticizer, 1-2% of a biomimetic mineralization layer precursor and the balance of deionized water, the green base material is a blend of a chitosan-polyethylene glycol graft and polylactic acid; the doping amount of Y3 in the nano enzyme is 3-4at%. The antibacterial agent is excellent and lasting in antibacterial effect, has no migration risk of the antibacterial agent, and can guarantee food safety; a green base material and a degradable plasticizer are adopted, so that natural degradation is realized, and environmental pollution is avoided; the mechanical property is good, the aging resistance is realized, and the oxygen barrier property is strong; the food packaging box is suitable for various foods, effectively prolongs the shelf life, and meets the requirement of green packaging.

The invention relates to application of ten antibacterial peptides in the antimicrobial field. The ten antibacterial peptides have strong antibacterial activity on multi-drug-resistant bacteria, including but not limited to gram-negative bacteria such as escherichia coli, pseudomonas aeruginosa, acinetobacter baumannii, klebsiella pneumoniae and the like, and gram-positive bacteria such as staphylococcus aureus, enterococcus faecalis and the like. Activity research proves that any one of the ten antibacterial peptides has a remarkable effect of inhibiting, killing or preventing microbial infection. Due to the strong antibacterial property of any antibacterial peptide, the antibacterial peptide has wide application potential in the aspects of preparing antibacterial drugs, preservatives, antibacterial coatings, antibacterial fibers, antibacterial packaging materials and the like. Due to the unique property of the antibacterial peptide in the aspect of antibacterial performance, a new direction is provided for the development of efficient and reliable antibacterial agents and antibacterial technologies and products in multiple fields.

The invention discloses a concrete sewage pipeline antibacterial anticorrosive coating material and a preparation method thereof, the concrete sewage pipeline antibacterial anticorrosive coating material is prepared from the following raw materials: water, water supply aluminum sludge ash, a water reducing agent, Portland cement, aggregate and antibacterial agents, the antibacterial agents are three antibacterial agents with different representativeness, respectively zinc oxide ZnO, copper phthalocyanine C32H16CuN8 and dihexadecyl dimethyl ammonium bromide C34H72BrN. Compared with a traditional concrete anticorrosive coating material, the prepared antibacterial anticorrosive coating material for the sewage pipeline has the advantages that the water supply aluminum sludge ash modified cement-based material is used as a carrier, and the antibacterial agent is used as a functional component to be doped to prepare a functional antibacterial coating, so that the microbial corrosion resistance and the stability of the coating are remarkably improved, and the antibacterial anticorrosive coating material is green and environment-friendly, and has a good application prospect. The method is low in cost, simple in process and convenient to prepare.

The invention discloses a stainless steel material for a food-grade straw and a preparation process of the stainless steel material, and relates to the technical field of stainless steel material plating. The silver coating and the antibacterial coating are arranged on the surface of the stainless steel material, and the stainless steel material has good wear resistance and antibacterial performance through the action of the double protective layers. Sulfonated polyphenylene sulfide is added into a silver plating solution, a plating layer is formed after electroplating, the surface of a stainless steel material is not prone to being scratched, the wear resistance of stainless steel is improved, quaternary ammonium salt modified tea polyphenol-nano-silver composite particles are added into the antibacterial coating, and through the synergistic antibacterial effect of quaternary ammonium salt, tea polyphenol and nano-silver, the wear resistance of the stainless steel material is improved. The broad-spectrum antibacterial property is realized, and the efficient antibacterial effect is achieved.

The invention relates to the technical field of materials, and discloses an antibacterial aluminum profile and a processing method thereof.The aluminum profile comprises an aluminum profile base body and an antibacterial coating, the antibacterial coating is formed by coating the surface of the aluminum profile base body with an antibacterial coating and curing the antibacterial coating, the antibacterial coating is prepared by taking acrylic resin emulsion as a film forming substance, and the antibacterial coating is prepared by curing the acrylic resin emulsion. The acrylic resin emulsion is formed by mixing acrylic resin emulsion, an inorganic filler, a dispersing agent and the like, an acrylic resin molecular chain in the acrylic resin emulsion is high in crosslinking density and large in cohesion, and the adhesive force and the impact resistance of the coating can be enhanced in cooperation with a large number of ether bonds and rigid biphenyl and heterocyclic structures provided by the crosslinking type reinforcing monomer; the advantages of the coating can be efficiently exerted by adding the inorganic filler, the hardness and other mechanical properties of the coating are improved, in addition, a large number of quaternary ammonium salt functional groups can endow the coating with a broad-spectrum antibacterial effect, and the aluminum profile can maintain a sterile environment.

The invention relates to the technical field of polyether-ether-ketone composite materials, in particular to a conjugated polythiophene-polyether-ether-ketone-based high-antibacterial coating and a preparation method thereof.The preparation method comprises the steps that hydroxyl modified boron nitride with photocatalytic capacity and aminated PEEK are subjected to melt blending to generate chemical bonding, and a BN-OH / PEEK-NH2 composite fine powder material is formed; then carrying out oxidative polymerization on the BN-OH / PEEK-NH2 composite fine powder and a thiophene monomer under the action of an oxidizing agent, carrying out in-situ synthesis to obtain a polythiophene / BN-OH / PEEK-NH2 conjugated composite material, and subsequently spraying the polythiophene / BN-OH / PEEK-NH2 conjugated composite material to the surface of a base material to prepare a composite coating with excellent antibacterial property, high thermal stability and low friction coefficient; the antibacterial rate of the coating on escherichia coli and staphylococcus aureus under illumination reaches 90% or above, and the coating is suitable for the medical antibacterial field.

The invention discloses a method and a system for detecting an antibacterial coating micro guide wire. The method comprises the following steps: applying a composite stress field to a guide wire to obtain stress distribution data; determining a stress response abnormal area according to the stress distribution data and applying dual-frequency vibration excitation to obtain nonlinear vibration response data and vibration energy dissipation data; force-sensitive fluorescent molecules are applied to the stress response abnormal area for treatment, and conformational changes of the stress response abnormal area are monitored to obtain preliminary spatial distribution data of the microcracks; injecting a multi-ion fluorescent tracer into the micro-crack area, and monitoring the migration rule of the multi-ion fluorescent tracer to obtain pH value distribution data and oxidation-reduction potential distribution data; bacterial suspension with specific fluorescence response is injected into the micro-crack area, and antibacterial activity evaluation data is obtained by monitoring the fluorescence response of the bacterial suspension. According to the technical scheme, the microcracks on the surface of the antibacterial coating micro guide wire are accurately detected and positioned, and the influence degree of the microcracks on the antibacterial function can be accurately evaluated.

The invention relates to a flexible and high-strength composite piezoelectric fiber film as well as a preparation method and application thereof, and the preparation method comprises the following steps: dissolving PVDF (Polyvinylidene Fluoride) or a copolymer thereof in a solvent to obtain a first solution; dissolving a strong dipole moment asymmetric polar inorganic metal salt in a solvent to obtain a second solution; uniformly mixing the first solution and the second solution, adding the multifunctional bio-based polymer, performing ultrasonic stirring until a uniform composite spinning solution is formed, and performing electrostatic spinning to obtain the composite piezoelectric fiber film. The fiber film provided by the invention integrates the mechanical strength and chemical stability of PVDF and copolymer thereof and the flexibility and water absorption of bio-based polymer. Meanwhile, inorganic metal salt is introduced to play a role of a beta-phase nucleating agent in the electrostatic spinning PVDF crystallization process, the piezoelectric output performance of the electrostatic spinning PVDF nano piezoelectric composite film is enhanced, and the mechanical performance of the fiber film is improved through the metal coordination effect of metal ions and hydroxyl or carboxyl on the bio-based polymer; the application potential in the fields of sensors, battery diaphragms, antibacterial coatings and the like is expanded.

The invention discloses a hydrophobic antibacterial polymer, a preparation method and application in a hydrophobic antibacterial coating, and belongs to the technical field of high polymer materials, and the preparation method comprises the following steps: mixing a component A with a first organic solvent to obtain a solution 1, and mixing a component B with a second organic solvent to obtain a solution 2; blending the solution 1 and the solution 2, adding a component C and an initiator, and reacting to obtain a hydrophobic antibacterial polymer; dissolving the hydrophobic antibacterial polymer in a third organic solvent to obtain a solute solution; and coating the surfaces of fabrics, silicon wafers, steel and wood with the dissolved matter solution through spraying, dispensing and dipping, and curing to obtain the self-healing high-durability hydrophobic antibacterial coating capable of being freely coated. The preparation method disclosed by the invention is simple in process and low in cost, the obtained coating has excellent hydrophobicity, antibacterial property and environmental stability and also has self-repairing property and free coating property, and the service life and the use convenience of the coating are remarkably improved.

The invention relates to the technical field of biomedicine, and discloses a triclosan antibacterial coating surgical suture and a preparation method thereof.The suture comprises a base material and a surface antibacterial coating, the base material is selected from one of an absorbable single-strand material, an absorbable multi-strand material, a non-absorbable single-strand material and a non-absorbable multi-strand material, and the surface antibacterial coating is selected from one of an absorbable multi-strand material and a non-absorbable multi-strand material; the antibacterial coating comprises triclosan, a high-molecular carrier and an auxiliary agent, the surface energy of a hydrophobic material is improved, the porosity of a hydrophilic material is increased, the adhesive force between the coating and different base materials is ensured, the base materials can be covered, the uniformity deviation of the coating is avoided, and the coating is free of cracking or falling off through the combination of plasma cleaning and roughening treatment on the surface of the base materials. A synergistic system is formed by triclosan, nano-silver and titanium dioxide, a dual mechanism of targeted destruction of bacterial cell membranes and free radical oxidation is achieved, the antibacterial rate is increased, the MRSA inhibition rate is increased, the degradation rate is regulated and controlled through the polylactic acid-glycolic acid copolymer carrier molecular weight and the lactic acid / glycolic acid proportion, and a curing dynamic formula is combined.

The invention discloses an IPNs anti-corrosion antibacterial coating in a marine environment as well as a preparation method and application thereof, and belongs to the technical field of coatings. The coating comprises a semi-finished product A and a semi-finished product B in a weight ratio of 1: 1; the semi-finished product A comprises the following raw materials in parts by mass: 35-45 parts of acrylic acid, 1-4 parts of an antibacterial agent and 3-12 parts of a dispersing agent; the semi-finished product B comprises the following raw materials in parts by mass: 6-12 parts of a curing agent, 3-8 parts of a film-forming agent and 8-15 parts of a pH regulator; 20 to 32 parts of a filling agent; the curing agent comprises an organic silicon curing agent and a fatty acid anhydride curing agent in a mass ratio of (4-7): (2-6). The invention further provides a preparation method of the coating and application of the coating in marine operation equipment. The marine operation equipment comprises a naval vessel, an anchor chain, drilling equipment, an instrument and a culture net cage. The anti-corrosion and antibacterial performance of the coating is effectively improved, the curing time is short, the subsequent coating method is simple and easy to implement, and the coating is suitable for large-scale production.

The invention discloses a preparation method of a coating loaded with an antibacterial coating. The preparation method comprises the following steps: pretreating a titanium sheet, preparing an electrolyte, preparing Ti (at) col-I, preparing Carat UiO-66, preparing a Ti (at) col-I (at) Carat UiO-66 coating, and preparing a Ti (at) col-I (at) Carat UiO-66 (at) LBL coating. According to the coating preparation method and the implant provided by the invention, the carvacrol-loaded UiO-66 mineralized collagen coating is prepared by utilizing an electrochemical deposition and layer-by-layer self-assembly technology, so that the surface osseointegration capability of a titanium-based material is improved, the surface of the titanium-based material is endowed with antibacterial capability, and infection around the implant is reduced; the initial stability and the clinical curative effect are improved.

The utility model discloses a composite antibacterial polyester filament, belongs to the technical field of textiles, and solves the problems that if the composite antibacterial polyester filament is required to have antibacterial performance from inside to outside, natural fibers are required to be combined together when the composite antibacterial polyester filament is required to be changed into spinning, and for pure physical spinning, the composite antibacterial polyester filament cannot have antibacterial performance inside and outside at present. Comprising a special-shaped section core wire and a plurality of outer wrapping wires, a plurality of spacing bar grooves are formed in the outer ring of the special-shaped section core wire, the spacing bar grooves are filled with a plurality of antibacterial particles, the special-shaped section core wire is arranged in a self-twisting mode, the outer wrapping wires are all arranged on the outer ring of the special-shaped section core wire, and the outer sides of the outer wrapping wires are coated with antibacterial coatings. Antibacterial particles are contained in the spacing bar grooves, openings of the spacing bar grooves are covered with the outer wrapping filaments, the particles are clamped after the special-shaped cross section core filaments are self-twisted, the internal and external antibacterial effect is ensured, natural fibers do not need to be added, and the purity of the polyester filaments is kept.

The invention provides a super-lubricity antibacterial coating material and a preparation method and application thereof, and relates to the technical field of medical implant materials, and the preparation method comprises the following steps: S1, respectively pretreating silver nanoparticles and polyethylene glycol; s2, the pretreated silver nanoparticles are placed in a first solvent, a silver nanoparticle solution is obtained, then a silane reagent and a catalyst are added, a silanization reaction is carried out, and activated silver nanoparticles are obtained; s3, placing a hydrophilic monomer in a second solvent, and then adding the activated silver nanoparticles to obtain a silver nanoparticle modified hydrophilic monomer; s4, putting the pretreated polyethylene glycol and an activating agent into a third solvent, and carrying out activating treatment to obtain an activated polyethylene glycol solution; and S5, putting the hydrophilic monomer modified by the silver nanoparticles into the activated polyethylene glycol solution to obtain the super-lubricity antibacterial coating material. When the surface of a silica gel catheter is coated with the super-lubricity antibacterial coating material, the lubricity and antibacterial property of the catheter are remarkably improved.

The invention provides a fluorescent antibacterial acrylic emulsion as well as a preparation method and application thereof. The fluorescent antibacterial acrylic emulsion comprises an acrylic monomer, AIE fluorescent micromolecules, an antibacterial quaternary ammonium salt monomer, a nonionic emulsifier, a cationic emulsifier, an initiator, a stabilizer and deionized water. The cosolvent of the water-based acrylic coating is water, no VOC (volatile organic compound) is discharged when the water-based acrylic coating is used, and harm to the environment and human bodies is reduced to the minimum; meanwhile, the antibacterial coating is prepared in a positive ion and ROS joint antibacterial mode, and the antibacterial effect is more excellent; and a convenient detection method for reflecting the change of the antibacterial property of the coating through the fluorescence change of the coating avoids the trouble of professional biological detection.

The invention relates to the technical field of stainless steel bands, and particularly discloses a wear-resistant duplex stainless steel band and a processing technology thereof. The method specifically comprises the following steps that S1, the surface of a duplex stainless steel band is electroplated with an iron-nickel-copper layer, and a stainless steel band A is obtained; the plating solution comprises the following components: 40-50 g / L of nickel sulfate hexahydrate, 20-30 g / L of ferric sulfate, 30-40 g / L of copper sulfate pentahydrate, 35-45 g / L of sodium citrate dehydrate, 25-30 g / L of sodium acetate and 20-25 g / L of sodium hypophosphite; s2, uniformly mixing organic silicon resin, hydrogen-containing silicone oil, ethanol, nano silicon carbide and a corrosion-resistant antibacterial agent to obtain a corrosion-resistant antibacterial coating; s3, the surface of the stainless steel band A is coated with the corrosion-resistant antibacterial coating, drying is conducted at the room temperature, and a stainless steel band B with a corrosion-resistant antibacterial coating on the surface is obtained; and coating gallium-containing zinc oxide sol on the surface of the stainless steel band B, and carrying out heat treatment to obtain the wear-resistant duplex stainless steel band with a gallium-containing zinc oxide layer on the surface.

The invention discloses an antibiotic-loaded lubricating antibacterial medical coating as well as a preparation method and application thereof. The preparation method comprises the following steps: coating a polymer substrate embedded with an initiator with a prepolymer solution, and carrying out ultraviolet irradiation reaction to prepare a lubricating hydrogel coating; the preparation method comprises the following steps: sequentially carrying out ultrasonic cleaning in an ethanol solution and an aqueous solution, drying, soaking in an antibiotic solution, regulating and controlling the loading capacity of antibiotics by controlling the pH value of the antibiotic solution, taking out, washing with the aqueous solution, and drying to obtain the lubricating antibacterial coating. According to the method, a hydrogel coating loading platform for loading the antibiotics only through post-adsorption is constructed, the loading capacity of the antibiotics in the coating can be regulated and controlled through the pH value of an antibiotic solution in the post-adsorption process, and the method effectively widens the adjustable range of the loading capacity of the antibiotics such as rifampicin; according to the invention, on-demand regulation and control of antibiotic load and related release curves in the hydrogel coating under different application scenes can be realized, and an effective multifunctional strategy is provided for reducing related infection of interventional medical catheters.

The invention discloses a polyurethane coating and a preparation method thereof, and belongs to the technical field of antibacterial coatings. The preparation method of the polyurethane coating comprises the following steps: carrying out acyl chloride substitution reaction on a phenolic substance and a chlorine donor to obtain an intermediate reactant, and carrying out conjugate addition reaction on the intermediate reactant and an amine substance with hydroxyl groups at two ends to obtain antibacterial diol; reacting the antibacterial diol with isocyanate to obtain a polyurethane coating; the phenolic substance is selected from at least one of thymol, carvacrol, paeonol, catechol and theaflavin. The antibacterial coating is applied to the aspect of an antibacterial coating of a food contact part, the problem that the antibacterial property of an existing antibacterial coating is difficult to last is solved, and the antibacterial coating has the synergistic antibacterial effect of killing and defending bacteria.

The invention provides an antibacterial polyurethane acrylate film material embedded with N-substituted benzisothiazolinone and alkenyl functionalized quaternary phosphonium salt, and belongs to the field of organic antibacterial coatings. N-substituted alkenyl of benzisothiazolinone is functionalized, tri (4-methoxyphenyl) phosphine alkenyl is functionalized, and the antibacterial polyurethane acrylate film material is prepared. Double bonds are introduced into a benzisothiazolinone structural unit and a tri (4-methoxyphenyl) phosphine structural unit, N-substituted benzisothiazolinone (NIT) and tri (4-methoxyphenyl) (nonyl-8-ene-1-yl) phosphonium bromide (TPC9) are grafted into a polyurethane acrylate main chain at the same time, and by means of the remarkable antibacterial activity of the NIT and the TPC9 on escherichia coli and staphylococcus aureus, the polyurethane acrylate can be used for preparing the antibacterial polyurethane acrylate. A broad-spectrum antibacterial material is prepared, and a corresponding antibacterial coating can be used for modifying the surface of a base material.

The invention discloses a slow-release antibacterial and antioxidant composite preservative film and a preparation method thereof. The slow-release antibacterial and antioxidant composite preservative film is prepared from a chitosan matrix and Chuzhou chrysanthemum essential oil nano-emulsion loaded in the chitosan matrix, the Chuzhou chrysanthemum essential oil nano-emulsion comprises Chuzhou chrysanthemum essential oil, a surfactant and a cosurfactant, and the average particle size of the Chuzhou chrysanthemum essential oil nano-emulsion is smaller than 200 nm; the composite preservative film has the function of slowly releasing the Chuzhou chrysanthemum essential oil and shows antibacterial and antioxidant activity; the preparation method comprises the following steps: firstly preparing Chuzhou chrysanthemum essential oil into a nano-emulsion by adopting a nano-encapsulation method through a high-pressure homogenization method to form the Chuzhou chrysanthemum essential oil nano-emulsion, then embedding the Chuzhou chrysanthemum essential oil nano-emulsion into chitosan to prepare an active chitosan composite film, and finally applying the antibacterial coating material to food preservation. The antibacterial coating film not only can effectively inhibit pathogenic microorganism infection in berry storage and logistics transportation in a wider spectrum, but also can regulate physiological metabolism of picked berries, delay the senescence process and reduce loss of internal moisture.

The invention discloses a gamma-polyglutamic acid and hydrophilic polysiloxane composite material and application thereof, and belongs to the technical field of medical antibacterial coating materials. The gamma-polyglutamic acid and hydrophilic polysiloxane composite material is prepared from a hydrophilic polysiloxane aqueous solution and a gamma-polyglutamic acid aqueous solution through an ionic cross-linking reaction, the hydrophilic polysiloxane is prepared by sequentially carrying out click chemical reaction and ionization modification on polysiloxane with a side chain containing vinyl and a sulfydryl-containing compound; the sulfydryl-containing compound also contains a carboxylic acid group or an amino-terminated group; when the sulfydryl-containing compound further contains carboxylic acid groups, the raw materials of the ionic cross-linking reaction further comprise an aqueous solution containing divalent metal cations. The composite material has low swelling rate and good antibacterial performance, and can be used for long-acting stable antibacterial. As an antibacterial coating, the composite material is suitable for the surfaces of medical apparatuses and instruments made of different materials, and has a wide application prospect.

The invention relates to a preparation method of leather with a multi-antibacterial type long-acting antibacterial function. The preparation method comprises the following steps of wet blue leather pretreatment, antibacterial retanning, filling dyeing, fat liquoring, antibacterial treatment, drying finishing and antibacterial coating. Wherein the antibacterial retanning adopts eucalyptus oil / dialdehyde cyclodextrin as an aldehyde retanning agent for aldehyde retanning; in the antibacterial treatment, eucalyptus oil and beta-cyclodextrin are used as antibacterial agents to carry out antibacterial occurrence treatment, the eucalyptus oil and the beta-cyclodextrin take essential oil extracted from natural herbaceous plant eucalyptus leaves as clathrate compounds, the beta-cyclodextrin is used as a main body, and a modified antibacterial agent beta-cyclodextrin and eucalyptus oil clathrate compound is prepared through a molecular clathration technology. As an antibacterial agent, an occurrence process is designed for antibacterial treatment; the antibacterial coating adopts a coating containing silver ions to be applied to a leather coating process; through triple antibiosis, the leather is more durable in antibiosis performance and more efficient.

The invention belongs to the technical field of tensile experiments, and discloses product tensile test mechanical experiment equipment which comprises a base, a detection groove is formed in the surface of the base, fixing plates are symmetrically installed on the two sides of the inner wall of the detection groove, and driving structures are fixedly installed on the opposite sides of the two fixing plates. The device is provided with a trapezoidal block, a coating detection head, a fixing rod and the like, during detection, the driving structure drives the lifting plate to enable the trapezoidal block to move downwards, the coating detection head at the bottom is used for detecting the thickness of an antibacterial coating on the surface of an unstretched antibacterial suture line, then the trapezoidal block continues to move downwards, the thickness of the antibacterial coating on the surface of the unstretched antibacterial suture line is detected, and the thickness of the antibacterial coating on the surface of the unstretched antibacterial suture line is detected. And then the antibacterial suture line is extruded to be changed into a V shape, so that the stretched antibacterial suture line is in contact with the coating detection heads on the two sides of the trapezoidal block, and the influence of stretching on the antibacterial coating on the surface of the antibacterial suture line can be judged by comparing data detected at the bottom and the side parts for multiple times.

The invention relates to the technical field of packaging materials, in particular to a preparation method of a food heat-preservation environment-friendly quick-transportation packaging bag. The prepared quick-transportation packaging bag sequentially comprises an outer film layer, a heat preservation layer, an aluminum foil layer and an inner film layer from outside to inside. The outer film layer and the inner film layer are made of a blend of polylactic acid, carboxymethyl starch and glycerol, the thermal insulation layer is formed by compounding a phase change capsule, silicon dioxide aerogel and a polyurethane adhesive on an aluminum foil layer, the phase change capsule takes a mixture of n-octadecane and paraffin as a core material and takes Arabic gum as a wall material, and the outer surface of the wall material is coated with a stearic acid film layer; an antibacterial coating containing microwave modified beewax, a functional additive and 3-aminopropyltriethoxysilane is sprayed on the inner surface of the inner film layer; the prepared quick-transportation packaging bag has excellent heat preservation performance and antibacterial performance, also has good degradability, is environmentally friendly and can meet multiple requirements of modern food logistics for packaging.

The invention relates to an enzyme response antibacterial carbon dot and a preparation method and application thereof.The carbon dot takes a copper-doped carbon dot as a core and is covalently grafted with a hyaluronic acid shell layer through amidation reaction to form a composite nano material Cu-CDs (at) HA, specifically, soluble copper salt and folic acid are subjected to a hydrothermal reaction to obtain the copper-doped carbon dot, carboxyl is activated through EDC / NHS in a buffer system, and the carbon dot is prepared. And performing grafting reaction with hyaluronic acid to obtain a target product. The hyaluronidase-containing antibacterial composition can be specifically degraded and release antibacterial components under the action of hyaluronidase, shows good bacterial responsive bactericidal performance, has the minimum inhibitory concentrations of 8 g / mL and 16 g / mL for staphylococcus aureus and escherichia coli respectively, and has peroxidase-like activity and free radical scavenging capacity. The antibacterial carbon dots can be used for preparing intelligent wound dressings, antibacterial coatings and other biomedical materials, and have the advantages of responsive drug release, efficient antibacterial property and promotion of wound repair.

The invention belongs to the technical field of medical interventional catheters, and particularly relates to a modified parylene-based antibacterial coating and a preparation method thereof, and is characterized in that a monomer molecular structure of a high-molecular compound is formed by carboxyl-containing parylene and parylene N through a gas deposition process together to form a parylene polymer with the surface containing carboxyl, and the modified parylene-based antibacterial coating is prepared from the modified parylene-based antibacterial coating and the preparation method of the modified parylene-based antibacterial coating. Then guanidine salt or antibacterial peptide reacts with carboxyl and is grafted on the parylene polymer coating. The composite material can be applied to the related aspects of biological medicine, has excellent antibacterial and anti-adhesion properties, and also has the beneficial effects of water resistance, moisture resistance, solid lubrication, small friction force, relatively low interface constant and the like; the preparation method is simple and low in cost.