689 results about "Antibacterial coating" patented technology

The invention discloses a portable wound surface protection brace and an application method thereof, and belongs to the technical field of medical instruments. The brace is of a cylindrical structure, is made of EVA materials, has flexibility, non-toxic characteristics and good supporting performance and is externally wrapped with cotton cloth and provided with ventilation through holes, high-density cotton strips are fixed to the two ends of the inner wall to form a hollow structure, and the circumference of the outer wall can be adjusted through at least three sets of bandages with hook-and-loop fasteners. And an antibacterial coating is added, so that clinical application is expanded. During application, a wound surface is subjected to liquid extraction and hydrogen peroxide cleaning in the earlier stage and then covered with insulin mixed normal saline gauze, and the dressing is prevented from making contact with clothes in cooperation with a brace; and smearing mupirocin ointment in the later stage and performing infrared irradiation, and continuously using the brace to keep the wound dry and zero contact. The brace can be repeatedly used, can adapt to various wound types and patient body types, effectively solves the problems of wound adhesion and friction in traditional nursing, creates a high-oxygen healing environment, remarkably shortens wound healing time, relieves pain of patients and improves life quality, and has good clinical application and popularization value.

The invention relates to the technical field of food packaging materials, in particular to a cerium dioxide nano-enzyme modified antibacterial coating and application of the cerium dioxide nano-enzyme modified antibacterial coating in food packaging. The biomimetic mineralization layer comprises the following components in percentage by weight: 35-45% of a green base material, 8-12% of dopamine modified yttrium-doped cerium dioxide nano-enzyme, 4-6% of a composite antibacterial agent, 3-4% of a natural cross-linking agent, 2-3% of a degradable plasticizer, 1-2% of a biomimetic mineralization layer precursor and the balance of deionized water, the green base material is a blend of a chitosan-polyethylene glycol graft and polylactic acid; the doping amount of Y3 in the nano enzyme is 3-4at%. The antibacterial agent is excellent and lasting in antibacterial effect, has no migration risk of the antibacterial agent, and can guarantee food safety; a green base material and a degradable plasticizer are adopted, so that natural degradation is realized, and environmental pollution is avoided; the mechanical property is good, the aging resistance is realized, and the oxygen barrier property is strong; the food packaging box is suitable for various foods, effectively prolongs the shelf life, and meets the requirement of green packaging.

The invention relates to application of ten antibacterial peptides in the antimicrobial field. The ten antibacterial peptides have strong antibacterial activity on multi-drug-resistant bacteria, including but not limited to gram-negative bacteria such as escherichia coli, pseudomonas aeruginosa, acinetobacter baumannii, klebsiella pneumoniae and the like, and gram-positive bacteria such as staphylococcus aureus, enterococcus faecalis and the like. Activity research proves that any one of the ten antibacterial peptides has a remarkable effect of inhibiting, killing or preventing microbial infection. Due to the strong antibacterial property of any antibacterial peptide, the antibacterial peptide has wide application potential in the aspects of preparing antibacterial drugs, preservatives, antibacterial coatings, antibacterial fibers, antibacterial packaging materials and the like. Due to the unique property of the antibacterial peptide in the aspect of antibacterial performance, a new direction is provided for the development of efficient and reliable antibacterial agents and antibacterial technologies and products in multiple fields.

The invention discloses a concrete sewage pipeline antibacterial anticorrosive coating material and a preparation method thereof, the concrete sewage pipeline antibacterial anticorrosive coating material is prepared from the following raw materials: water, water supply aluminum sludge ash, a water reducing agent, Portland cement, aggregate and antibacterial agents, the antibacterial agents are three antibacterial agents with different representativeness, respectively zinc oxide ZnO, copper phthalocyanine C32H16CuN8 and dihexadecyl dimethyl ammonium bromide C34H72BrN. Compared with a traditional concrete anticorrosive coating material, the prepared antibacterial anticorrosive coating material for the sewage pipeline has the advantages that the water supply aluminum sludge ash modified cement-based material is used as a carrier, and the antibacterial agent is used as a functional component to be doped to prepare a functional antibacterial coating, so that the microbial corrosion resistance and the stability of the coating are remarkably improved, and the antibacterial anticorrosive coating material is green and environment-friendly, and has a good application prospect. The method is low in cost, simple in process and convenient to prepare.

The invention discloses a stainless steel material for a food-grade straw and a preparation process of the stainless steel material, and relates to the technical field of stainless steel material plating. The silver coating and the antibacterial coating are arranged on the surface of the stainless steel material, and the stainless steel material has good wear resistance and antibacterial performance through the action of the double protective layers. Sulfonated polyphenylene sulfide is added into a silver plating solution, a plating layer is formed after electroplating, the surface of a stainless steel material is not prone to being scratched, the wear resistance of stainless steel is improved, quaternary ammonium salt modified tea polyphenol-nano-silver composite particles are added into the antibacterial coating, and through the synergistic antibacterial effect of quaternary ammonium salt, tea polyphenol and nano-silver, the wear resistance of the stainless steel material is improved. The broad-spectrum antibacterial property is realized, and the efficient antibacterial effect is achieved.

The invention relates to the technical field of polyether-ether-ketone composite materials, in particular to a conjugated polythiophene-polyether-ether-ketone-based high-antibacterial coating and a preparation method thereof.The preparation method comprises the steps that hydroxyl modified boron nitride with photocatalytic capacity and aminated PEEK are subjected to melt blending to generate chemical bonding, and a BN-OH / PEEK-NH2 composite fine powder material is formed; then carrying out oxidative polymerization on the BN-OH / PEEK-NH2 composite fine powder and a thiophene monomer under the action of an oxidizing agent, carrying out in-situ synthesis to obtain a polythiophene / BN-OH / PEEK-NH2 conjugated composite material, and subsequently spraying the polythiophene / BN-OH / PEEK-NH2 conjugated composite material to the surface of a base material to prepare a composite coating with excellent antibacterial property, high thermal stability and low friction coefficient; the antibacterial rate of the coating on escherichia coli and staphylococcus aureus under illumination reaches 90% or above, and the coating is suitable for the medical antibacterial field.

The invention discloses a method and a system for detecting an antibacterial coating micro guide wire. The method comprises the following steps: applying a composite stress field to a guide wire to obtain stress distribution data; determining a stress response abnormal area according to the stress distribution data and applying dual-frequency vibration excitation to obtain nonlinear vibration response data and vibration energy dissipation data; force-sensitive fluorescent molecules are applied to the stress response abnormal area for treatment, and conformational changes of the stress response abnormal area are monitored to obtain preliminary spatial distribution data of the microcracks; injecting a multi-ion fluorescent tracer into the micro-crack area, and monitoring the migration rule of the multi-ion fluorescent tracer to obtain pH value distribution data and oxidation-reduction potential distribution data; bacterial suspension with specific fluorescence response is injected into the micro-crack area, and antibacterial activity evaluation data is obtained by monitoring the fluorescence response of the bacterial suspension. According to the technical scheme, the microcracks on the surface of the antibacterial coating micro guide wire are accurately detected and positioned, and the influence degree of the microcracks on the antibacterial function can be accurately evaluated.

The invention discloses a hydrophobic antibacterial polymer, a preparation method and application in a hydrophobic antibacterial coating, and belongs to the technical field of high polymer materials, and the preparation method comprises the following steps: mixing a component A with a first organic solvent to obtain a solution 1, and mixing a component B with a second organic solvent to obtain a solution 2; blending the solution 1 and the solution 2, adding a component C and an initiator, and reacting to obtain a hydrophobic antibacterial polymer; dissolving the hydrophobic antibacterial polymer in a third organic solvent to obtain a solute solution; and coating the surfaces of fabrics, silicon wafers, steel and wood with the dissolved matter solution through spraying, dispensing and dipping, and curing to obtain the self-healing high-durability hydrophobic antibacterial coating capable of being freely coated. The preparation method disclosed by the invention is simple in process and low in cost, the obtained coating has excellent hydrophobicity, antibacterial property and environmental stability and also has self-repairing property and free coating property, and the service life and the use convenience of the coating are remarkably improved.

The invention relates to the technical field of biomedicine, and discloses a triclosan antibacterial coating surgical suture and a preparation method thereof.The suture comprises a base material and a surface antibacterial coating, the base material is selected from one of an absorbable single-strand material, an absorbable multi-strand material, a non-absorbable single-strand material and a non-absorbable multi-strand material, and the surface antibacterial coating is selected from one of an absorbable multi-strand material and a non-absorbable multi-strand material; the antibacterial coating comprises triclosan, a high-molecular carrier and an auxiliary agent, the surface energy of a hydrophobic material is improved, the porosity of a hydrophilic material is increased, the adhesive force between the coating and different base materials is ensured, the base materials can be covered, the uniformity deviation of the coating is avoided, and the coating is free of cracking or falling off through the combination of plasma cleaning and roughening treatment on the surface of the base materials. A synergistic system is formed by triclosan, nano-silver and titanium dioxide, a dual mechanism of targeted destruction of bacterial cell membranes and free radical oxidation is achieved, the antibacterial rate is increased, the MRSA inhibition rate is increased, the degradation rate is regulated and controlled through the polylactic acid-glycolic acid copolymer carrier molecular weight and the lactic acid / glycolic acid proportion, and a curing dynamic formula is combined.

The invention discloses a preparation method of a coating loaded with an antibacterial coating. The preparation method comprises the following steps: pretreating a titanium sheet, preparing an electrolyte, preparing Ti (at) col-I, preparing Carat UiO-66, preparing a Ti (at) col-I (at) Carat UiO-66 coating, and preparing a Ti (at) col-I (at) Carat UiO-66 (at) LBL coating. According to the coating preparation method and the implant provided by the invention, the carvacrol-loaded UiO-66 mineralized collagen coating is prepared by utilizing an electrochemical deposition and layer-by-layer self-assembly technology, so that the surface osseointegration capability of a titanium-based material is improved, the surface of the titanium-based material is endowed with antibacterial capability, and infection around the implant is reduced; the initial stability and the clinical curative effect are improved.

The invention provides a super-lubricity antibacterial coating material and a preparation method and application thereof, and relates to the technical field of medical implant materials, and the preparation method comprises the following steps: S1, respectively pretreating silver nanoparticles and polyethylene glycol; s2, the pretreated silver nanoparticles are placed in a first solvent, a silver nanoparticle solution is obtained, then a silane reagent and a catalyst are added, a silanization reaction is carried out, and activated silver nanoparticles are obtained; s3, placing a hydrophilic monomer in a second solvent, and then adding the activated silver nanoparticles to obtain a silver nanoparticle modified hydrophilic monomer; s4, putting the pretreated polyethylene glycol and an activating agent into a third solvent, and carrying out activating treatment to obtain an activated polyethylene glycol solution; and S5, putting the hydrophilic monomer modified by the silver nanoparticles into the activated polyethylene glycol solution to obtain the super-lubricity antibacterial coating material. When the surface of a silica gel catheter is coated with the super-lubricity antibacterial coating material, the lubricity and antibacterial property of the catheter are remarkably improved.

The invention provides a fluorescent antibacterial acrylic emulsion as well as a preparation method and application thereof. The fluorescent antibacterial acrylic emulsion comprises an acrylic monomer, AIE fluorescent micromolecules, an antibacterial quaternary ammonium salt monomer, a nonionic emulsifier, a cationic emulsifier, an initiator, a stabilizer and deionized water. The cosolvent of the water-based acrylic coating is water, no VOC (volatile organic compound) is discharged when the water-based acrylic coating is used, and harm to the environment and human bodies is reduced to the minimum; meanwhile, the antibacterial coating is prepared in a positive ion and ROS joint antibacterial mode, and the antibacterial effect is more excellent; and a convenient detection method for reflecting the change of the antibacterial property of the coating through the fluorescence change of the coating avoids the trouble of professional biological detection.

The invention discloses an antibiotic-loaded lubricating antibacterial medical coating as well as a preparation method and application thereof. The preparation method comprises the following steps: coating a polymer substrate embedded with an initiator with a prepolymer solution, and carrying out ultraviolet irradiation reaction to prepare a lubricating hydrogel coating; the preparation method comprises the following steps: sequentially carrying out ultrasonic cleaning in an ethanol solution and an aqueous solution, drying, soaking in an antibiotic solution, regulating and controlling the loading capacity of antibiotics by controlling the pH value of the antibiotic solution, taking out, washing with the aqueous solution, and drying to obtain the lubricating antibacterial coating. According to the method, a hydrogel coating loading platform for loading the antibiotics only through post-adsorption is constructed, the loading capacity of the antibiotics in the coating can be regulated and controlled through the pH value of an antibiotic solution in the post-adsorption process, and the method effectively widens the adjustable range of the loading capacity of the antibiotics such as rifampicin; according to the invention, on-demand regulation and control of antibiotic load and related release curves in the hydrogel coating under different application scenes can be realized, and an effective multifunctional strategy is provided for reducing related infection of interventional medical catheters.

The invention discloses a polyurethane coating and a preparation method thereof, and belongs to the technical field of antibacterial coatings. The preparation method of the polyurethane coating comprises the following steps: carrying out acyl chloride substitution reaction on a phenolic substance and a chlorine donor to obtain an intermediate reactant, and carrying out conjugate addition reaction on the intermediate reactant and an amine substance with hydroxyl groups at two ends to obtain antibacterial diol; reacting the antibacterial diol with isocyanate to obtain a polyurethane coating; the phenolic substance is selected from at least one of thymol, carvacrol, paeonol, catechol and theaflavin. The antibacterial coating is applied to the aspect of an antibacterial coating of a food contact part, the problem that the antibacterial property of an existing antibacterial coating is difficult to last is solved, and the antibacterial coating has the synergistic antibacterial effect of killing and defending bacteria.

The invention provides an antibacterial polyurethane acrylate film material embedded with N-substituted benzisothiazolinone and alkenyl functionalized quaternary phosphonium salt, and belongs to the field of organic antibacterial coatings. N-substituted alkenyl of benzisothiazolinone is functionalized, tri (4-methoxyphenyl) phosphine alkenyl is functionalized, and the antibacterial polyurethane acrylate film material is prepared. Double bonds are introduced into a benzisothiazolinone structural unit and a tri (4-methoxyphenyl) phosphine structural unit, N-substituted benzisothiazolinone (NIT) and tri (4-methoxyphenyl) (nonyl-8-ene-1-yl) phosphonium bromide (TPC9) are grafted into a polyurethane acrylate main chain at the same time, and by means of the remarkable antibacterial activity of the NIT and the TPC9 on escherichia coli and staphylococcus aureus, the polyurethane acrylate can be used for preparing the antibacterial polyurethane acrylate. A broad-spectrum antibacterial material is prepared, and a corresponding antibacterial coating can be used for modifying the surface of a base material.

The invention discloses a slow-release antibacterial and antioxidant composite preservative film and a preparation method thereof. The slow-release antibacterial and antioxidant composite preservative film is prepared from a chitosan matrix and Chuzhou chrysanthemum essential oil nano-emulsion loaded in the chitosan matrix, the Chuzhou chrysanthemum essential oil nano-emulsion comprises Chuzhou chrysanthemum essential oil, a surfactant and a cosurfactant, and the average particle size of the Chuzhou chrysanthemum essential oil nano-emulsion is smaller than 200 nm; the composite preservative film has the function of slowly releasing the Chuzhou chrysanthemum essential oil and shows antibacterial and antioxidant activity; the preparation method comprises the following steps: firstly preparing Chuzhou chrysanthemum essential oil into a nano-emulsion by adopting a nano-encapsulation method through a high-pressure homogenization method to form the Chuzhou chrysanthemum essential oil nano-emulsion, then embedding the Chuzhou chrysanthemum essential oil nano-emulsion into chitosan to prepare an active chitosan composite film, and finally applying the antibacterial coating material to food preservation. The antibacterial coating film not only can effectively inhibit pathogenic microorganism infection in berry storage and logistics transportation in a wider spectrum, but also can regulate physiological metabolism of picked berries, delay the senescence process and reduce loss of internal moisture.

The invention discloses a gamma-polyglutamic acid and hydrophilic polysiloxane composite material and application thereof, and belongs to the technical field of medical antibacterial coating materials. The gamma-polyglutamic acid and hydrophilic polysiloxane composite material is prepared from a hydrophilic polysiloxane aqueous solution and a gamma-polyglutamic acid aqueous solution through an ionic cross-linking reaction, the hydrophilic polysiloxane is prepared by sequentially carrying out click chemical reaction and ionization modification on polysiloxane with a side chain containing vinyl and a sulfydryl-containing compound; the sulfydryl-containing compound also contains a carboxylic acid group or an amino-terminated group; when the sulfydryl-containing compound further contains carboxylic acid groups, the raw materials of the ionic cross-linking reaction further comprise an aqueous solution containing divalent metal cations. The composite material has low swelling rate and good antibacterial performance, and can be used for long-acting stable antibacterial. As an antibacterial coating, the composite material is suitable for the surfaces of medical apparatuses and instruments made of different materials, and has a wide application prospect.

The invention relates to a preparation method of leather with a multi-antibacterial type long-acting antibacterial function. The preparation method comprises the following steps of wet blue leather pretreatment, antibacterial retanning, filling dyeing, fat liquoring, antibacterial treatment, drying finishing and antibacterial coating. Wherein the antibacterial retanning adopts eucalyptus oil / dialdehyde cyclodextrin as an aldehyde retanning agent for aldehyde retanning; in the antibacterial treatment, eucalyptus oil and beta-cyclodextrin are used as antibacterial agents to carry out antibacterial occurrence treatment, the eucalyptus oil and the beta-cyclodextrin take essential oil extracted from natural herbaceous plant eucalyptus leaves as clathrate compounds, the beta-cyclodextrin is used as a main body, and a modified antibacterial agent beta-cyclodextrin and eucalyptus oil clathrate compound is prepared through a molecular clathration technology. As an antibacterial agent, an occurrence process is designed for antibacterial treatment; the antibacterial coating adopts a coating containing silver ions to be applied to a leather coating process; through triple antibiosis, the leather is more durable in antibiosis performance and more efficient.

The invention belongs to the technical field of tensile experiments, and discloses product tensile test mechanical experiment equipment which comprises a base, a detection groove is formed in the surface of the base, fixing plates are symmetrically installed on the two sides of the inner wall of the detection groove, and driving structures are fixedly installed on the opposite sides of the two fixing plates. The device is provided with a trapezoidal block, a coating detection head, a fixing rod and the like, during detection, the driving structure drives the lifting plate to enable the trapezoidal block to move downwards, the coating detection head at the bottom is used for detecting the thickness of an antibacterial coating on the surface of an unstretched antibacterial suture line, then the trapezoidal block continues to move downwards, the thickness of the antibacterial coating on the surface of the unstretched antibacterial suture line is detected, and the thickness of the antibacterial coating on the surface of the unstretched antibacterial suture line is detected. And then the antibacterial suture line is extruded to be changed into a V shape, so that the stretched antibacterial suture line is in contact with the coating detection heads on the two sides of the trapezoidal block, and the influence of stretching on the antibacterial coating on the surface of the antibacterial suture line can be judged by comparing data detected at the bottom and the side parts for multiple times.

The invention relates to the technical field of packaging materials, in particular to a preparation method of a food heat-preservation environment-friendly quick-transportation packaging bag. The prepared quick-transportation packaging bag sequentially comprises an outer film layer, a heat preservation layer, an aluminum foil layer and an inner film layer from outside to inside. The outer film layer and the inner film layer are made of a blend of polylactic acid, carboxymethyl starch and glycerol, the thermal insulation layer is formed by compounding a phase change capsule, silicon dioxide aerogel and a polyurethane adhesive on an aluminum foil layer, the phase change capsule takes a mixture of n-octadecane and paraffin as a core material and takes Arabic gum as a wall material, and the outer surface of the wall material is coated with a stearic acid film layer; an antibacterial coating containing microwave modified beewax, a functional additive and 3-aminopropyltriethoxysilane is sprayed on the inner surface of the inner film layer; the prepared quick-transportation packaging bag has excellent heat preservation performance and antibacterial performance, also has good degradability, is environmentally friendly and can meet multiple requirements of modern food logistics for packaging.

The invention relates to an enzyme response antibacterial carbon dot and a preparation method and application thereof.The carbon dot takes a copper-doped carbon dot as a core and is covalently grafted with a hyaluronic acid shell layer through amidation reaction to form a composite nano material Cu-CDs (at) HA, specifically, soluble copper salt and folic acid are subjected to a hydrothermal reaction to obtain the copper-doped carbon dot, carboxyl is activated through EDC / NHS in a buffer system, and the carbon dot is prepared. And performing grafting reaction with hyaluronic acid to obtain a target product. The hyaluronidase-containing antibacterial composition can be specifically degraded and release antibacterial components under the action of hyaluronidase, shows good bacterial responsive bactericidal performance, has the minimum inhibitory concentrations of 8 g / mL and 16 g / mL for staphylococcus aureus and escherichia coli respectively, and has peroxidase-like activity and free radical scavenging capacity. The antibacterial carbon dots can be used for preparing intelligent wound dressings, antibacterial coatings and other biomedical materials, and have the advantages of responsive drug release, efficient antibacterial property and promotion of wound repair.

The application discloses a high-performance corrugated carton with waterproof and antibacterial functions and a preparation process thereof, and the process comprises the following steps: S1, providing a corrugated paperboard substrate; S2, coating a barrier-enhanced coating liquid on the inner and outer surfaces of the corrugated paperboard substrate respectively, and forming a barrier-enhanced coating layer after solidification; S3, coating a composite antibacterial coating liquid, and forming a composite antibacterial coating layer after solidification to obtain a composite corrugated paperboard; and S4, using the composite corrugated paperboard to make a corrugated carton. The composite antibacterial coating layer can improve the waterproof performance of the composite corrugated paperboard and endow the composite corrugated paperboard with excellent antibacterial performance. Through cooperation of the barrier-enhanced coating layer and the composite antibacterial coating layer and with the excellent barrier effect of the barrier-enhanced coating layer, the waterproof performance of the composite corrugated paperboard can be further improved while avoiding the risk that active oxygen brought by the composite antibacterial coating layer may damage the performance of the corrugated paperboard substrate, and the mechanical strength of the composite corrugated paperboard can be improved, so that the service life of the composite corrugated paperboard can be ensured.

The invention discloses an antibacterial coating which comprises a component A and a component B. The component A comprises the following raw materials in parts by weight: 40-60 parts of epoxy resin, 15-35 parts of polyamide resin, 5-10 parts of tea tree essential oil, 1-3 parts of di (2-ethylhexyl) phthalate, 1-2 parts of fumed silica, 1-2 parts of acrylate, 1-2 parts of sodium phosphate and 1-2 parts of polyvinyl ether. The component B comprises the following raw materials in parts by weight: 20-30 parts of modified nano zinc oxide, 40-60 parts of an antibacterial curing agent, 15-20 parts of butanol and 2-10 parts of acetone. The weight ratio of the component A to the component B is 8: (2-4), and the water-resistant coating is excellent in mechanical property, high in adhesive force and good in water resistance.

The application relates to a modified polylactic acid oligomer and a preparation method and application thereof. The modified polylactic acid oligomer has the structure shown in the following formula (I). The modified polylactic acid oligomer obtained by copolymerization of 5-hydroxy-2-hexenoic acid and lactic acid has more excellent and stable and persistent antibacterial activity, the antibacterial efficiency is greatly improved, the sterilization rate is improved, and the sterilization time is shortened; when the modified polylactic acid oligomer is applied to various antibacterial coatings and textile finishing, the surface no longer has a wet sticky feeling, the commercialization and wide application of the material are more beneficial, and the modified polylactic acid oligomer has higher affinity to a target substrate, so that the persistence, stability and washability of a surface coating can be improved.

The invention discloses an antibacterial coating and a preparation method and application thereof in DUWLs pipelines, and relates to the technical field of medical materials, the antibacterial coating comprises PDA, SBMA and AgNPs; the antibacterial coating has high protein adsorption resistance, and adsorption of protein in the DUWLs pipeline can be effectively inhibited; the antibacterial coating has a good antibacterial effect and can effectively inhibit the proliferation of bacteria in the DUWLs pipeline and prevent the formation of a biological membrane; the antibacterial rate to staphylococcus aureus and escherichia coli reaches 100%, the bacterial form is incomplete, and cytoplasm leaks; meanwhile, the antibacterial coating can reduce erosion damage of the disinfectant to the DUWLs pipeline, and the antibacterial coating has important application value for solving the problem of DUWLs pollution.

The invention relates to the technical field of medical sutures, and particularly discloses a PDO barb suture with an antibacterial coating and a preparation method of the PDO barb suture. According to the PDO barb suture line with the antibacterial coating, a PDO mixed suture line base body with good mechanical performance is obtained by blending, spinning and weaving L-polylactic acid and poly (p-dioxanone) according to a certain proportion; hyaluronic acid is used as a gel matrix, 4-(oxirane-2-yl methoxyl) butyl acrylate is grafted to hyaluronic acid for alkenyl modification, then the hyaluronic acid is mixed with quercetin-3-O-glucoside and TCS-ZIF-8 loaded with oridonin, and the antibacterial gel coating is obtained. And finally, dipping the PDO mixed suture line matrix into the antibacterial gel coating and carrying out ultraviolet irradiation in the presence of a photoinitiator to prepare the PDO mixed suture line. The suture line prepared by the invention has the advantages of smooth coating, efficient and lasting antibacterial performance, high strength, good flexibility, small friction force and high operability.

The embodiment of the invention provides an emergency clinical data real-time sharing method and system based on the Internet of Things. Wherein the biological parameters of the wound part are monitored in real time by using the intelligent dressing integrated with the antibacterial coating, and the data are transmitted to the emergency clinical data collaboration platform through the low-power wide area network. According to the relationship between the aperture of the antibacterial coating and the drug release rate, an optimal drug release curve is screened out. In combination with cross-mechanism wound infection historical data, federal learning is adopted to construct an infection risk evolution model, and infection risk quantitative parameters are generated. The data are comprehensively analyzed, the drug release rate and the effective time window are dynamically adjusted, and the abnormal correlation threshold value is corrected. And based on the analysis result, automatically generating a wound infection early warning instruction and an emergency treatment data sharing instruction so as to assist in clinical decision making. According to the technical scheme provided by the embodiment of the invention, the efficiency and accuracy of real-time sharing of emergency clinical data can be improved.

The invention discloses a pH / temperature dual-response type quaternary ammonium salt-nano silver-zinc oxide composite antibacterial coating material as well as a preparation method and application thereof, and belongs to the technical field of antibacterial materials. The antibacterial effective life of the coated product is at least up to 5 years. The coating product is preferably a gastrointestinal endoscope, efficient bacteriostasis is achieved under the condition that the light transmittance of the gastrointestinal endoscope is not affected, biocompatibility is good, safety is high, precise controlled release of silver ions is achieved, and biotoxicity caused by sudden release of the silver ions is avoided. The quaternary ammonium salt-nano silver-zinc oxide composite coating material with the pH / temperature dual-response antibacterial effect is finally obtained through the steps of preparing a composite carrier material, loading antibacterial metal elements, constructing a pH / temperature dual-response polymer network and the like in sequence. A high-performance, safe and environment-friendly antibacterial coating system which is rapid in sterilization, precise in controlled release and long-acting in interference resistance is constructed, and an antibacterial solution with high technical adaptability is provided for the fields of medical treatment, food, water treatment and the like.

The invention discloses an antibacterial coating for a concrete surface as well as a preparation method and application of the antibacterial coating, and relates to the technical field of functional polymers. The antibacterial coating for the concrete surface is prepared from the following raw materials in parts by weight: 100 parts of a monomer mixture, 0.7 to 3.1 parts of an initiator, 0.3 to 2.0 parts of a chain transfer agent and 75 to 125 parts of a solvent, wherein the monomer mixture comprises a methacrylate monomer, an acrylate monomer, sodium acrylate, a urea methacrylate monomer and a capsaicin derivative in a molar ratio of (12-60): (20-60): (2-10): (2-10): (1-5). The antibacterial coating for the concrete surface is easy to prepare and operate, low in cost and environmentally friendly, and raw materials are easy to obtain; the capsaicin derivative monomer is introduced into the antibacterial coating for the concrete surface, so that the antibacterial activity of the resin is improved, and the problem of biological fouling of a concrete structure in marine infrastructure is solved.

The invention provides metal organic framework loaded guanidyl polymer nanoparticles as well as a preparation method and application thereof. The nanoparticles comprise a copper-based metal-organic framework material and a guanidyl-containing polymer loaded on the surface of the copper-based metal-organic framework material; the copper-based metal-organic framework material comprises a copper trimesic acid complex, the copper trimesic acid complex has a porous structure and an octahedral structure, and the guanidyl-containing polymer is distributed in the porous structure and on the surface of the octahedral structure; the nanoparticles are insoluble in water, and the particle size of the nanoparticles is nanoscale. When the antibacterial agent is added into the resin, the non-dissolution antibacterial coating can be prepared, the guanidyl-containing polymer is not easy to dissolve out, the antibacterial coating is endowed with good antibacterial property, and the problems that the hydrophilic guanidyl-containing polymer and the coating resin are poor in compatibility and easy to leach out are solved.